Sample cross-contamination protection device for a genetic analysis instrument

Abstract

The utility model relates to sample storage technical field discloses a sample cross -contamination protection device of genetic analysis instrument, include: sample storage cabinet, negative pressure anti -pollution mechanism, negative pressure anti -pollution mechanism sets up at the back of sample storage cabinet, negative pressure anti -pollution mechanism can make the inside of sample storage cabinet produce negative pressure, open and close mechanism, open and close mechanism sets up at the front of sample storage cabinet, open and close mechanism is used for to the front of sample storage cabinet carries out half -closed. The utility model discloses the design of negative pressure anti -pollution mechanism whole, pipeline air -suction fan works, can extract air from the inner chamber of sample storage cabinet, if sample produces leakage, will with air extraction of sample's leakage, then through the component in the filtration cabin to its filtration, avoid the problem that the cross -contamination between sample is easy to appear, avoid the problem that sample can cause the pollution of indoor, guarantee sample subsequent analysis result's accuracy, increase the security in sample storage process.

Description

Technical Field

[0001] This utility model relates to the field of sample storage technology, specifically to a sample cross-contamination protection device for a gene analysis instrument. Background Technology

[0002] Gene analysis instruments are a class of high-tech devices used to detect, sequence, and analyze the DNA / RNA sequences of organisms. They utilize molecular biology techniques to perform functions such as gene mutation screening, genetic disease diagnosis, and pathogen typing. Their core components include high-throughput sequencers and capillary electrophoresis systems, and they are widely used in medical research, clinical diagnosis, and agricultural testing.

[0003] Samples awaiting use in gene analysis instruments are temporarily stored in cabinets. Traditional cabinets do not have the function of preventing cross-contamination. If the sample is not properly sealed, it may leak, leading to cross-contamination and affecting the accuracy of subsequent analysis results. Utility Model Content

[0004] The purpose of this invention is to provide a sample cross-contamination protection device for gene analysis instruments, which solves the problem in the prior art that if samples are leaked when temporarily stored in a cabinet, cross-contamination may occur.

[0005] This utility model provides the following technical solution: a sample cross-contamination protection device for a gene analysis instrument, comprising: Sample storage cabinet; A negative pressure anti-contamination mechanism is installed on the back of the sample storage cabinet, which can generate negative pressure inside the sample storage cabinet. An opening and closing mechanism is provided on the front of the sample storage cabinet, and the opening and closing mechanism is used to partially close the front of the sample storage cabinet. The negative pressure anti-contamination mechanism includes a connecting cover, which is fixedly connected to the back of the sample storage cabinet. A ducted suction fan is fixedly connected to the back of the connecting cover, and a filter chamber is fixedly connected to the back of the ducted suction fan. A support arm is fixedly installed on the outer wall of the filter chamber, and the end of the support arm is fixedly installed on the outer wall of the connecting cover. A door is rotatably connected to the top of the filter chamber, and an exhaust pipe is fixedly connected to the back of the filter chamber.

[0006] As a preferred embodiment of the above technical solution, an inner support frame is fixedly installed on the inner wall of the filter chamber, a connecting frame is fixedly connected to the back of the inner support frame, and a HEPA filter is movably inserted into the inner cavity of the connecting frame.

[0007] As a preferred embodiment of the above technical solution, a limiting block is fixedly installed on the front of the inner support frame, a coarse filter frame is movably inserted into the inner side of the limiting block, and a magnetic block is fixedly installed on the inner wall of the coarse filter frame, the magnetic block being magnetically connected to the inner support frame.

[0008] As a preferred embodiment of the above technical solution, a track rod is fixedly installed between the two sides of the inner wall of the sample storage cabinet, a movable partition frame is slidably connected to the outer wall of the track rod, a handle is welded to the outer wall of the movable partition frame, and a partition is fixedly installed on the inner wall of the movable partition frame.

[0009] As a preferred embodiment of the above technical solution, the opening and closing mechanism includes a front door panel, which is fixedly installed on the front of the sample storage cabinet. The front of the front door panel has through holes and through slots, and a support block is fixedly installed on the front of the front door panel.

[0010] As a preferred embodiment of the above technical solution, a servo motor is fixedly installed on the top of the support block, a bidirectional lead screw is rotatably connected to the inner wall of the support block, the output shaft of the servo motor is fixedly connected to the end of the bidirectional lead screw, a moving block is threadedly connected to the outer wall of the bidirectional lead screw, and a movable strip is fixedly installed on the outer wall of the moving block.

[0011] Compared with the prior art, the beneficial effects of this utility model are: This invention utilizes a negative pressure anti-contamination mechanism. After the duct fan is activated, it can extract air from the inner cavity of the sample storage cabinet. If a sample leaks, the leaked sample will be extracted along with the air and then filtered by components inside the filter chamber. This prevents cross-contamination between samples and avoids contamination of the room by the samples, ensuring the accuracy of subsequent analysis results and increasing the safety of sample storage. Attached Figure Description

[0012] Figure 1 This is a perspective view of the present utility model; Figure 2 This is a schematic diagram of the negative pressure anti-pollution mechanism of this utility model; Figure 3 This is a schematic diagram of the internal structure of the filter chamber of this utility model; Figure 4 This is a schematic diagram of the opening and closing mechanism of this utility model; Figure 5 This is a schematic diagram of the internal structure of the sample storage cabinet of this utility model.

[0013] In the diagram: 1. Sample storage cabinet; 11. Track rod; 12. Movable partition frame; 13. Handle; 14. Partition; 2. Negative pressure anti-contamination mechanism; 21. Connecting cover; 22. Duct suction fan; 23. Filter chamber; 231. Inner support frame; 232. Limiting block; 233. Coarse filter frame; 234. Magnetic block; 235. Connecting frame; 236. HEPA filter; 24. Support arm; 25. Door; 26. Exhaust pipe; 3. Opening and closing mechanism; 31. Front door panel; 311. Through hole; 312. Through groove; 32. Support block; 33. Servo motor; 34. Two-way lead screw; 35. Moving block; 36. Movable strip. Detailed Implementation

[0014] The technical solutions of the present invention will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present invention.

[0015] like Figures 1-5 As shown, this utility model provides a technical solution: a sample cross-contamination protection device for a gene analysis instrument, comprising: Sample storage cabinet 1; Negative pressure anti-contamination mechanism 2 is installed on the back of sample storage cabinet 1. Negative pressure anti-contamination mechanism 2 can generate negative pressure inside sample storage cabinet 1. The opening and closing mechanism 3 is located on the front of the sample storage cabinet 1 and is used to partially close the front of the sample storage cabinet 1. The negative pressure anti-contamination mechanism 2 includes a connecting cover 21, which is fixedly connected to the back of the sample storage cabinet 1. A duct suction fan 22 is fixedly connected to the back of the connecting cover 21, and a filter chamber 23 is fixedly connected to the back of the duct suction fan 22. A support arm 24 is fixedly installed on the outer wall of the filter chamber 23, and the end of the support arm 24 is fixedly installed on the outer wall of the connecting cover 21. A door 25 is rotatably connected to the top of the filter chamber 23, and an exhaust pipe 26 is fixedly connected to the back of the filter chamber 23. After the sample is stored inside the sample storage cabinet 1, the duct suction fan 22 is controlled to work and draw air from the inner cavity of the sample storage cabinet 1. If a sample leaks, the leaked sample will be drawn out with the air and then filtered by the components inside the filter chamber 23 to avoid cross-contamination between samples. The end of the exhaust pipe 26 can be connected to an air pipe of appropriate length to exhaust the air to the outside.

[0016] As one implementation method in this embodiment, such as Figure 3As shown, an inner support frame 231 is fixedly installed on the inner wall of the filter chamber 23. A connecting frame 235 is fixedly connected to the back of the inner support frame 231. A HEPA filter 236 is movably inserted into the inner cavity of the connecting frame 235. The HEPA filter 236 is used to purify the exhaust air and prevent environmental pollution. The HEPA filter 236 is positioned in the connecting frame 235 by bolts on the connecting frame 235. After opening the chamber door 25, the HEPA filter 236 can be disassembled by loosening the bolts for cleaning, replacement and other maintenance.

[0017] As one implementation method in this embodiment, such as Figure 3 As shown, a limiting block 232 is fixedly installed on the front of the inner support frame 231. A coarse filter frame 233 is movably inserted into the inner side of the limiting block 232. A magnetic block 234 is fixedly installed on the inner wall of the coarse filter frame 233. The magnetic block 234 is magnetically connected to the inner support frame 231. The coarse filter frame 233 is used to pre-filter the air passing through the HEPA filter 236, reduce the filtration load of the HEPA filter 236, and extend its service life. The magnetic block 234 is embedded inside the coarse filter frame 233. The coarse filter frame 233 is magnetically installed on the inner support frame 231 through the magnetic block 234. After opening the hatch 25, the user can disassemble and maintain the coarse filter frame 233.

[0018] As one implementation method in this embodiment, such as Figure 5 As shown, a track rod 11 is fixedly installed between the two sides of the inner wall of the sample storage cabinet 1. A movable partition frame 12 is slidably connected to the outer wall of the track rod 11. A handle 13 is welded to the outer wall of the movable partition frame 12. A partition 14 is fixedly installed on the inner wall of the movable partition frame 12. The user can slide the movable partition frame 12 on the track rod 11 to adjust the position of the partition 14, thereby dividing the inner cavity of the sample storage cabinet 1 so that each sample is in a separate cavity to prevent cross-contamination. After the position of the movable partition frame 12 is adjusted, the bolts on the movable partition frame 12 can be tightened to lock its position.

[0019] As one implementation method in this embodiment, such as Figure 4 As shown, the opening and closing mechanism 3 includes a front door panel 31, which is fixedly installed on the front of the sample storage cabinet 1. The front of the front door panel 31 has a through hole 311 and a through groove 312. A support block 32 is fixedly installed on the front of the front door panel 31. When the duct fan 22 is running, the inner cavity of the sample storage cabinet 1 can be filled with air through the through hole 311 or the through groove 312. If the indoor air quality of the environment is poor, a HEPA filter needs to be installed at the through hole 311 on the inside of the front door panel 31. The installed HEPA filter can cover the through hole 311. The design of the through groove 312 makes it convenient for users to store and retrieve samples in the inner cavity of the sample storage cabinet 1.

[0020] As one implementation method in this embodiment, such as Figure 4 As shown, a servo motor 33 is fixedly installed on the top of the support block 32, and a bidirectional lead screw 34 is rotatably connected to the inner wall of the support block 32. The output shaft of the servo motor 33 is fixedly connected to the end of the bidirectional lead screw 34. A moving block 35 is threadedly connected to the outer wall of the bidirectional lead screw 34, and a movable strip 36 is fixedly installed on the outer wall of the moving block 35. In the initial state, the two movable strips 36 are closed on the front of the through slot 312. If it is necessary to store or retrieve the sample, the servo motor 33 can be controlled to work, drive the bidirectional lead screw 34 to rotate, and drive the two moving blocks 35 to move away from each other. At this time, the movable strip 36 will be withdrawn from the front of the through slot 312 and moved to the vicinity of the through hole 311, so that the sample can be stored or retrieved. The front door panel 31 and the movable strip 36 are both made of transparent plastic, which makes it easy for users to observe the status of the samples inside the sample storage cabinet 1.

[0021] Working principle: When samples need to be stored or retrieved, the servo motor 33 can be controlled to rotate the bidirectional lead screw 34, driving the two moving blocks 35 to move away from each other. At this time, the movable strip 36 will be withdrawn from the front of the through slot 312 and moved to the vicinity of the through hole 311, so that samples can be stored or retrieved. The user can slide the movable partition frame 12 on the track rod 11 to adjust the position of the partition 14 and divide the inner cavity of the sample storage cabinet 1 so that each sample is in a separate cavity to prevent cross-contamination. After the sample is stored or retrieved, the servo motor 33 is controlled to drive the movable strip 36 to reset, and the duct suction fan 22 is controlled to work to extract air from the inner cavity of the sample storage cabinet 1. If the sample leaks, the leaked sample will be extracted with the air. The HEPA filter 236 is used to purify the exhaust air to prevent environmental pollution.

[0022] The above embodiments are only used to illustrate the technical solution of this utility model, and are not intended to limit it.

Claims

1. A sample cross-contamination protection device for a gene analysis instrument, characterized in that, include: Sample storage cabinet (1); Negative pressure anti-contamination mechanism (2) is installed on the back of the sample storage cabinet (1), and the negative pressure anti-contamination mechanism (2) can generate negative pressure inside the sample storage cabinet (1); The opening and closing mechanism (3) is located on the front of the sample storage cabinet (1) and is used to partially close the front of the sample storage cabinet (1). The negative pressure anti-pollution mechanism (2) includes a connecting cover (21), which is fixedly connected to the back of the sample storage cabinet (1). A duct suction fan (22) is fixedly connected to the back of the connecting cover (21). A filter chamber (23) is fixedly connected to the back of the duct suction fan (22). A support arm (24) is fixedly installed on the outer wall of the filter chamber (23). The end of the support arm (24) is fixedly installed on the outer wall of the connecting cover (21). A door (25) is rotatably connected to the top of the filter chamber (23). An exhaust pipe (26) is fixedly connected to the back of the filter chamber (23).

2. The sample cross-contamination protection device for a gene analysis instrument according to claim 1, characterized in that: An inner support frame (231) is fixedly installed on the inner wall of the filter chamber (23), and a connecting frame (235) is fixedly connected to the back of the inner support frame (231). A HEPA filter (236) is movably inserted into the inner cavity of the connecting frame (235).

3. The sample cross-contamination protection device for a gene analysis instrument according to claim 2, characterized in that: A limiting block (232) is fixedly installed on the front of the inner support frame (231). A coarse filter frame (233) is movably inserted into the inner side of the limiting block (232). A magnetic block (234) is fixedly installed on the inner wall of the coarse filter frame (233). The magnetic block (234) is magnetically connected to the inner support frame (231).

4. The sample cross-contamination protection device for a gene analysis instrument according to claim 1, characterized in that: A track rod (11) is fixedly installed between the two sides of the inner wall of the sample storage cabinet (1). A movable partition frame (12) is slidably connected to the outer wall of the track rod (11). A handle (13) is welded to the outer wall of the movable partition frame (12). A partition plate (14) is fixedly installed on the inner wall of the movable partition frame (12).

5. The sample cross-contamination protection device for a gene analysis instrument according to claim 4, characterized in that: The opening and closing mechanism (3) includes a front door panel (31), which is fixedly installed on the front of the sample storage cabinet (1). The front of the front door panel (31) has a through hole (311) and a through groove (312), and a support block (32) is fixedly installed on the front of the front of the front door panel (31).

6. The sample cross-contamination protection device for a gene analysis instrument according to claim 5, characterized in that: A servo motor (33) is fixedly installed on the top of the support block (32). A bidirectional lead screw (34) is rotatably connected to the inner wall of the support block (32). The output shaft of the servo motor (33) is fixedly connected to the end of the bidirectional lead screw (34). A moving block (35) is threadedly connected to the outer wall of the bidirectional lead screw (34). A movable strip (36) is fixedly installed on the outer wall of the moving block (35).

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