Hollow fiber membrane with improved separation performance and production of a hollow fiber membrane with improved separation performance
Patent Information
- Authority / Receiving Office
- DE · DE
- Patent Type
- Patents
- Current Assignee / Owner
- FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH
- Filing Date
- 2017-12-08
- Publication Date
- 2026-05-07
AI Technical Summary
Existing methods for sterilizing hollow fiber membranes made of polysulfone and polyvinylpyrrolidone for medical use, particularly in blood treatment, cause deterioration of permeation properties due to PVP mobilization and pore blockage, leading to inconsistent separation performance and sharpness, especially in the medium molecular weight range.
A method involving steam sterilization with transmembrane fluid transfer, specifically using water vapor or steam, is employed to prevent PVP deposition and membrane clumping, maintaining high sterility and blood compatibility while ensuring homogeneous performance across the membrane filter.
The method results in hollow fiber membranes with improved separation efficiency and sharpness in the medium molecular weight range, maintaining high retention of high molecular weight proteins like albumin, and uniform permeation properties throughout the filter, enhancing overall filtration performance and biocompatibility.