Method for stabilizing the combination of ascorbic acid and ferulic acid

Abstract

Method for stabilizing the combination of ascorbic acid and ferulic acid. The present invention relates to a method for preparing a cosmetic composition comprising ascorbic acid or one of its derivatives and ferulic acid or one of its derivatives, comprising the extemporaneous mixing of: (i) a first aqueous composition comprising ascorbic acid or one of its derivatives and polyquaternium-67, with (ii) a second composition comprising, in at least one glycol, ferulic acid or one of its derivatives. It also relates to a method for the treatment of keratinous materials, in particular skin, comprising the preparation and then the application of such a mixture. Figure for the abstract: none

Description

Title of the invention: Process for stabilizing the combination of ascorbic acid and ferulic acid

[0001] The present invention relates to a process for preparing a composition ensuring the stabilization of the association of ascorbic acid or one of its derivatives and ferulic acid or one of its derivatives.

[0002] In cosmetic applications, it is common to add ascorbic acid (vitamin C) as an active ingredient which, thanks to its collagen synthesis stimulating properties, improves skin firmness. Ascorbic acid is also known for its antioxidant properties. It is also common to use ferulic acid or its derivatives to improve the texture, hydration, regularity, suppleness and / or homogeneity, transparency and / or radiance of the complexion of weakened skin.

[0003] However, ascorbic acid and ferulic acid are compounds that are difficult to stabilize in aqueous media, and the stabilization conditions are different for ascorbic acid and ferulic acid. In particular, the best stability condition for ascorbic acid is at pH 6, while the best stability condition for ferulic acid is at pH less than 4. There is no common formulation zone in terms of pH for the co-formulation of these two acids.

[0004] There is therefore a need for an aqueous cosmetic composition comprising ascorbic acid and ferulic acid which is stable over a period of use of at least one month.

[0005] The present application aims to resolve the incompatibility of stabilization in the same product of the association of ascorbic acid and ferulic acid.

[0006] Surprisingly, the Applicant has demonstrated that the combination of a composition comprising ascorbic acid or one of its derivatives and poly-quaternium-67, and a composition comprising ferulic acid or one of its derivatives and a glycolic solvent, by an extemporaneous process, makes it possible to obtain a composition which is stable for at least 30 days.

[0007] Thus, the present invention relates to a process for preparing a cosmetic composition comprising ascorbic acid or one of its derivatives and ferulic acid or one of its derivatives, comprising the extemporaneous mixture of:

[0008] (i) a first aqueous composition comprising ascorbic acid or one of its derivatives and polyquaternium-67, with

[0009] (ii) a second composition comprising, in at least one glycol, ferulic acid or one of its derivatives.

[0010] In particular, said extemporaneous mixture is produced at room temperature.

[0011] By "room temperature" is meant a temperature of approximately 20°C to 25°C.

[0012] The cosmetic composition according to the invention, after mixing the first and second compositions (i) and (ii), has a pH of between 4 and 8, preferably between 5 and 7. Preferably, the composition according to the invention has a pH of 6.

[0013] The composition according to the invention is stable.

[0014] Preferably, the cosmetic composition according to the invention is stable at room temperature.

[0015] A composition is said to be stable when its macroscopic appearance (clarity and homogeneity) does not change after at least 30 days. In particular, the composition according to the invention has a clear and homogeneous appearance.

[0016] For the purposes of the present invention, the term “clear” means a composition having a transparent appearance.

[0017] For the purposes of the present invention, the term “homogeneous” means a composition consisting of a single phase, in other words monophasic.

[0018] The invention also relates to a stable cosmetic composition (hereinafter “stable cosmetic composition”) comprising, relative to the total weight of the composition:

[0019] - from 0.1 to 15% by weight of ascorbic acid or one of its derivatives, and

[0020] - from 0.01 to 1% by weight of ferulic acid or one of its derivatives,

[0021] said composition having a pH between 4 and 8, preferably between 5 and 7, preferably pH 6.

[0022] According to one embodiment, the composition according to the invention is substantially free of tocopherol. By "substantially free of tocopherol" is meant that the composition according to the invention has a tocopherol content of less than or equal to 2% by weight relative to the total weight of the composition, preferably less than or equal to 1% by weight, preferentially between 0.01% and 2% by weight. Preferably, the composition according to the invention is completely free of tocopherol.

[0023] According to one embodiment, the composition according to the invention is substantially free of vitamin E. By "substantially free of vitamin E" is meant that the composition according to the invention has a vitamin E content of less than or equal to 2% by weight relative to the total weight of the composition, preferably less than or equal to 1% by weight, preferentially between 0.01% and 2% by weight. Preferably, the composition according to the invention is completely free of vitamin E.

[0024] The invention also relates to a cosmetic process for caring for keratin materials, in particular the skin, which comprises (1) the process for preparing a cosmetic composition according to the invention, then (2) the application of this composition cosmetic on keratin materials, particularly the skin.

[0025] In particular, step (2) of applying the cosmetic composition takes place at the latest one month (i.e. at the latest 30 or 31 days) after step (1) of preparing said composition.

[0026] Furthermore, the invention also relates to the use of said composition in the cosmetic field, in particular for the care of keratin materials, in particular the skin.

[0027] For the purposes of the present invention, keratin materials mean skin.

[0028] By “skin” is meant the skin of the face and / or body, and the scalp.

[0029] The invention also relates to a kit for the care and / or treatment of keratin materials, in particular the skin, comprising (i) a first aqueous composition comprising ascorbic acid or one of its derivatives and polyquatemium-67, and (ii) a second composition comprising, in at least one glycol, ferulic acid or one of its derivatives. First aqueous composition (i)

[0030] The invention comprises a first aqueous composition (i) comprising ascorbic acid or one of its derivatives and polyquaternium-67.

[0031] Ascorbic acid or one of its derivatives

[0032] The ascorbic acid according to the invention can be in D or L form.

[0033] Preferably, ascorbic acid within the meaning of the invention corresponds to L-ascorbic acid, or vitamin C. It has the following structure:

[0034] [Chem.l] HQ t HAM HO OH

[0035] Composition (i) may also comprise an ascorbic acid derivative which is an ascorbic acid salt, for example sodium ascorbate, magnesium or sodium ascorbylphosphate, and glycosylated ascorbic acid.

[0036] Composition (i) may also comprise a derivative of ascorbic acid. Examples that may be mentioned are ose esters of ascorbic acid and metal salts of phosphorylated ascorbic acid.

[0037] Among the ose esters of ascorbic acid, mention may be made of the glycosylated, mannosylated, fructosylated, fucosylated, galactosylated N-acetylglucosamine, N-acetylmuramic derivatives of ascorbic acid and their mixtures and more especially ascorbyl-2 glucoside or 2-O-aD glucopyranosyl of L-ascorbic acid or 6-O-[3-D-galactopyranosyl] L-ascorbic acid. These latter compounds and their preparation processes are described in particular in documents EP 487 404, EP 425 066 and J05213736.

[0038] The metal salt of phosphorylated ascorbic acid may be chosen from alkali metal ascorbyl phosphates, alkaline earth metal ascorbyl phosphates and transition metal ascorbyl phosphates.

[0039] Ascorbic acid is notably available under the commercial reference Ascorbic Acid (L) from the company Reckon Organics, and under the reference Ascorbic Acid Ultra Fine Powder from the company DSM Nutritional Products.

[0040] Suitable ascorbic acid derivatives according to the present invention may be chosen from 5,6-di-O-dimethylsilylascorbate marketed under the reference PRO-AA by the company Exsymol, the potassium salt of dl-alpha-tocopheryl-dl-ascorbyl-phosphate marketed under the reference Sepivital EPC by the company Senju Pharmaceutical, magnesium ascorbyl phosphate, sodium ascorbyl phosphate marketed under the reference Stay-C 50 by the company Roche and ascorbyl glucoside marketed by the company Hayashibara.

[0041] Preferably, the first composition (i) comprises from 0.12% to 20% by weight of ascorbic acid or one of its derivatives relative to the total weight of the composition (i), preferably from 1% to 18% by weight, preferably from 10% to 17% by weight.

[0042] The stable cosmetic composition according to the invention comprises from 0.1% to 15% by weight of ascorbic acid or one of its derivatives relative to the total weight of the composition, preferably from 1% to 14% by weight, preferably from 5% to 13% by weight.

[0043] Polyquaternium-67

[0044] Preferably, the first composition (i) comprises from 0.1 to 1% by weight of poly-quaternium-67 relative to the total weight of the composition (i), preferably from 0.2 to 0.8% by weight, preferably from 0.2 to 0.5% by weight.

[0045] Polyquaternium-67 is for example marketed under the reference Softcat Polymer SL-100 by Amerchol (Dow Chemical).

[0046] Preferably, the stable cosmetic composition according to the invention comprises from 0.1 to 1% by weight of polyquaternium-67 relative to the total weight of composition, preferably from 0.2% to 0.8% by weight, preferably from 0.2% to 0.6% by weight.

[0047] Water

[0048] Preferably, the first composition (i) comprises at least 40% water by weight relative to the total weight of the composition (i), preferably at least 45% water by weight, preferably at least 50% water by weight, preferably at least 55% water by weight, preferably at least 60% water by weight.

[0049] The water used may be sterile demineralized water and / or a floral water such as rose water, cornflower water, chamomile water or linden water, and / or a natural thermal or mineral water, such as: Vittel water, Vichy basin water, Uriage water, Roche Posay water, Bourboule water, Enghien-les-Bains water, Saint Gervais-les-Bains water, Néris-les-Bains water, Allevar-les-Bains water, Digne water, Maizières water, Neyrac-les-Bains water, Lons-le-Saunier water, Eaux Bonnes, Rochefort water, Saint Christau water, Fumades water and Tercis-les-Bains water, Avène water.

[0050] Preferably, the composition (i) according to the invention is an aqueous solution. Preferably, the composition according to the invention is single-phase. By "single-phase" is meant that the composition according to the invention does not have a dispersed phase (also called a discontinuous phase) in the form of droplets in a dispersing phase (also called a continuous phase). Such a composition may be called a "serum". By "serum" is meant a composition with a fluid, runny texture.

[0051] Solvents

[0052] Preferably, the composition (i) according to the invention comprises at least one water-soluble organic solvent.

[0053] Preferably, by water-soluble organic solvent is meant organic solvents chosen from alcohols, polyols and their mixtures.

[0054] Among the alcohols, mention may be made of C1-C10 alcohols, more preferably C1-C5, such as ethanol, isopropanol, propanol and butanol.

[0055] The polyol may be chosen from polyols having from 2 to 20 carbon atoms, such as glycerol, diglycerol, propylene glycol, isoprene glycol, dipropylene glycol, butylene glycol, caprylyl glycol, hexylene glycol, 1,3-propanediol, pentylene glycol, polyethylene glycols having from 2 to 200 ethylene oxide units and mixtures thereof.

[0056] In particular, composition (i) comprises at least one organic solvent chosen from glycerol, pentylene glycol, caprylyl glycol and mixtures thereof.

[0057] Preferably, composition (i) comprises a mixture of glycerol, pentylene glycol and caprylyl glycol.

[0058] Preferably, the composition (i) according to the invention comprises from 0.1% to 35% by weight, preferably from 1% to 30% by weight, preferably from 5% to 25% by weight, preferably from 10% to 20% by weight, preferably from 15% to 19% by weight of organic solvent relative to the total weight of the composition (i).

[0059] Base

[0060] Composition (i) may optionally comprise at least one base.

[0061] The base may be an organic base or a mineral base.

[0062] As an example of an organic base, mention may be made of primary, secondary or tertiary alkylamines, for example triethylamine or butylamine.

[0063] As an example of a mineral base, we can cite metal hydroxides or

[0064]

[0065]

[0066]

[0067]

[0068]

[0069]

[0070]

[0071]

[0072]

[0073]

[0074]

[0075]

[0076] ammonium, such as LiOH, NaOH, KOH, Ca(OH)2, NH4OH, Mg(OH)2 or Zn(OH)2. Preferably, the base is chosen from mineral bases, preferably from alkali metal hydroxides, preferably sodium hydroxide or potassium hydroxide, advantageously sodium hydroxide. Preferably, when it comprises a base, composition (i) comprises from 0.1% to 10% by weight of base relative to the total weight of composition (i), preferably from 0.5% to 6% by weight, preferably from 1% to 5% by weight, preferentially from 2% to 4% by weight. Composition (i) may also comprise one or more additive(s) conventionally used in cosmetic compositions, preferably chosen from active ingredients, chelating agents, preservatives and perfumes. Preferably, among the additives which can be used, adenosine, sodium hyaluronate, trisodium ethylenediamine disuccinate, hydroxyacetophenone or mixtures thereof are preferred. Second composition (ii) The invention comprises a second composition (ii) comprising, in at least one glycol, ferulic acid or one of its derivatives. Ferulic acid Composition (ii) according to the invention comprises ferulic acid or one of its derivatives. Ferulic acid is the common name for [(4-hydroxy-3-methyl-3-phenyl]-3-propene-2-oic acid. It has the following structure formula (II): [Chem. 2] By "derivatives" of ferulic acid, we mean in particular its esters and / or salts and / or plant extracts containing it. Examples of ferulic acid "esters" include esters of ferulic acid and C1-C30 alcohols, in particular methyl ferulate, ethyl ferulate, isopropyl ferulate, octyl ferulate and oryzanyl ferulate. Examples of "salts" of ferulic acid include organic salts of ferulic acid, particularly sodium salts such as sodium ferulate and sodium isoferulate. Examples of "plant extracts" containing ferulic acid include: Rice, wheat, barley, oats, tree bark, poplar buds, asparagus, olives, berries. Preferably, the bran fraction of rice, wheat, barley, or oats will be used. In a particular method, wheat bran extract will be used.

[0077] Preferably, the ferulic acid derivatives are chosen from esters of ferulic acid and C1-C30 alcohols, organic salts of ferulic acid, plant extracts containing ferulic acid, and mixtures thereof.

[0078] Ferulic acid is notably available under the commercial reference Oryza Ferulix from the company Oryza Oil & Fat Chemicals.

[0079] Preferably, the second composition (ii) according to the invention comprises from 0.04 to 5% by weight of ferulic acid or one of its derivatives, relative to the total weight of the composition (ii), preferably from 0.5 to 4% by weight, and even more preferably from 1 to 3% by weight.

[0080] The stable cosmetic composition according to the invention comprises from 0.01 to 1% by weight of ferulic acid or one of its derivatives relative to the total weight of the composition, preferably from 0.1% to 0.8% by weight, preferably from 0.3% to 0.7% by weight.

[0081] Glycol

[0082] Composition (ii) according to the invention comprises at least one glycol. By glycol is meant a diol in which the two hydroxyl groups are carried by two different carbon atoms.

[0083] The glycol may be chosen from polyols having from 2 to 20 carbon atoms, such as glycerol, diglycerol, propylene glycol, isoprene glycol, dipropylene glycol, butylene glycol, caprylyl glycol, hexylene glycol, 1,3-propanediol, pentylene glycol, polyethylene glycols having from 2 to 200 ethylene oxide units or mixtures thereof.

[0084] Preferably, the glycol is dipropylene glycol.

[0085] Dipropylene glycol is notably available under the commercial reference Di-propylene Glycol from the company Ineos.

[0086] Preferably, the composition (ii) according to the invention comprises at least 20% by weight, preferably at least 30% by weight, preferably at least 40% by weight, preferably at least 50% by weight, preferably at least 60% by weight, preferably at least 70% by weight, preferably at least 80% by weight, preferably at least 85% by weight, preferably at least 90% by weight, preferably at least 95% by weight, preferably at least 98% by weight of glycol relative to the total weight of the composition (ii).

[0087] The composition in accordance with the invention can be obtained in a conventional manner by a person skilled in the art.

[0088] The expressions “between ... and ...” and “ranging from ... to ...” must be understood inclusively, unless otherwise specified.

[0089] The following examples will allow a better understanding of the invention, without however being limiting in nature. The raw materials are named by their chemical or INCI name. The quantities indicated are in % by weight of raw materials relative to the total weight of composition (% w / w), unless otherwise stated. EXAMPLES

[0090] I - Preparation of an extemporaneous composition according to the invention

[0091] A first composition (i) Cl based on ascorbic acid and a second composition (ii) C2 based on ferulic acid, according to the invention, are prepared according to the ingredients of the following table 1:

[0092] [Tables 1] Inventive composition of ascorbic acid (first composition (i)) Inventive composition of ferulic acid (second composition (ü)) Ingredients (% w / w) Cl C2 SODIUM HYDROXIDE Qs - DIPROPYLENE GLYCOL - Qsp 100 ASCORBIC ACID 16 - WATER Qsp 100 - SODIUM HYA-LURONATE 0.07 - GLYCERIN 6.67 - CAPRYLYL GLYCOL 0.4 - ADENOSINE 0.13 - POLYQUATERNIUM-67 0.31 - FERULIC ACID - 2 TRISODIUM ETHYLENEDIAMINE DI-SUCCINATE 0.27 - Preservative(s) Qs - PENTYLENE GLYCOL 10.67 -

[0093] A composition II (stable cosmetic composition according to the invention) is then prepared by extemporaneous mixing of 75% by weight of Cl and 25% by weight of C2 relative to the total weight of the mixture C1+C2. The composition obtained is as follows:

[0094] [Tables2] II Ingredients (%w / w) Composition after extemporaneous mixing of 75% Cl+ 25% C2 SODIUM HYDROXIDE 2.76 DIPROPYLENE GLYCOL 24.50 ASCORBIC ACID 12 WATER Qsp 100 SODIUM HYA-LURONATE 0.05 GLYCERIN 5.00 CAPRYLYL GLYCOL 0.30 ADENOSINE 0.10 POLYQUATERNIUM-67 0.23 FERULIC ACID 0.50 TRISODIUM ETHYL NEDIAMINE DI-SUCCINATE 0.20 Preservative(s) Qs PENTYLENE GLYCOL 8.00

[0095] II - Stability of the extemporaneous composition according to the invention

[0096] The stability of composition II (stable cosmetic composition according to the invention) was tested according to duplicated tests.

[0097] To evaluate the stability of the composition, the chemical losses of ascorbic acid and ferulic acid are evaluated on day 1, day 4, day 7, day 14, day 21, day 30 and day 60 after mixing Cl + C2, and at room temperature.

[0098] Measurement of chemical losses:

[0099] Chemical losses of ascorbic acid and ferulic acid are measured by a liquid chromatography method combined with UV detection, according to the following parameters:

[0100] Column: ACQUITY UPLC HSS T3 RP18 100x2.1mm in l.7pm

[0101] Eluent: Di-Sodium Hydrogen Phosphate Buffer at 0.006 mol / L, pH 2.1 / ACN (20 / 80 v / v)

[0102] Flow rate: 0.35ml / min

[0103] Injection volume: 1 pl

[0104] Temperature: 50°C

[0105] X-ray detection: UV from 200 to 300 nm:

[0106] The extraction of ascorbic acid is at 250nm, and the extraction of ferulic acid is at 320nm.

[0107] The results obtained are grouped in the following table 3:

[0108] [Tables3] Dosage (%w / w) Day 0 Day 1 Day 4 Day 7 Day 14 Day 21 Day 30 Day 60 Trial 1 Ascorbic acid 12.20 12.30 12.01 12.03 11.99 11.73 11.56 9.88 Ferulic acid 0.46 0.47 0.46 0.45 0.43 0.42 0.40 0.32 Trial 2 Ascorbic acid 12.30 12.30 12.30 12.02 11.91 11.75 11.70 10.08 Ferulic acid 0.47 0.47 0.47 0.45 0.43 0.42 0.41 0.33

[0109] Vitamin C (ascorbic acid) is stable for up to 2 months at room temperature (chemical loss <20%).

[0110] The stability of ferulic acid is consistent at room temperature for up to 1 month (at 3 weeks of use: 10% loss; at 4 weeks: 13% loss). From 2 months, the chemical loss is 30% which is no longer acceptable.

[0111] In conclusion, good stability of ascorbic acid and ferulic acid in composition II is observed for up to 1 month at room temperature after the first use (5 drops per day) of the extemporaneous mixture at pH6.

[0112] II - Stability of the extemporaneous composition according to the invention as a function of temperature

[0113] The stability of composition II (stable cosmetic composition according to the invention) has was tested at room temperature (RT) and at 45°C according to two independent tests.

[0114] To evaluate the stability of the composition, the chemical losses of ascorbic acid and ferulic acid are evaluated on day 7, day 14, day 21, day 28, day 21 and day 60 after mixing Cl + C2, at room temperature or at 45°C (protocol above).

[0115] Test 1:

[0116] [T ables 4] Temperature (°C) Dosage (%w / w) Day 0 Day 7 Day 14 Day 21 Day 28 Day 60 TA Ascorbic acid 12.20 12.07 12.12 11.90 11.70 11.30 Ferulic acid 0.46 0.47 0.46 0.44 0.43 0.34 45 Ascorbic acid 12.20 11.90 11.30 11.30 11.20 10.50 Ferulic acid 0.46 0.32 0.19 0.12 0.09 0.02

[0117] Test 2:

[0118] [Tables5] Temperature (°C) Dosage (%w / w) Day 0 Day 7 Day 14 Day 21 Day 28 Day 60 TA Ascorbic acid 12.30 12.00 11.95 11.90 11.90 11.30 Ferulic acid 0.47 0.47 0.45 0.44 0.43 0.35 45 Ascorbic acid 12.30 11.90 11.30 11.30 11.30 10.60 Ferulic acid 0.47 0.32 0.19 0.13 0.09 0.02

[0119] It is found that at room temperature, ascorbic acid is stable for up to two months (less than 9% loss), and ferulic acid is stable for at least 4 weeks.

[0120] At a temperature of 45°C, ascorbic acid remains stable for at least 4 weeks, but ferulic acid degrades significantly after 1 week (30% loss). A loss of ferulic acid of more than 96% is observed after 2 months at 45°C.

Claims

Claims

1. A process for preparing a cosmetic composition comprising ascorbic acid or one of its derivatives and ferulic acid or one of its derivatives, comprising the extemporaneous mixing of: (i) a first aqueous composition comprising ascorbic acid or one of its derivatives and polyquaternium-67, with (ii) a second composition comprising, in at least one glycol, ferulic acid or one of its derivatives.

2. A method according to claim 1, wherein the first composition (i) comprises between 0.12 and 20% by weight of ascorbic acid or one of its derivatives relative to the total weight of the composition (i), preferably from 1 to 18% by weight, preferably from 10 to 17% by weight.

3. A method according to claim 1 or 2, wherein the first composition (i) comprises at least 40% water by weight relative to the total weight of the composition (i), preferably at least 45% water by weight, preferably at least 50% water by weight, preferably at least 55% water by weight, more preferably at least 60% water by weight.

4. Method according to one of the preceding claims, in which the first composition (i) comprises from 0.1 to 1% by weight of poly-quaternium-67 relative to the total weight of the composition (i), preferably from 0.2 to 0.8% by weight, preferably from 0.2 to 0.5% by weight.

5. Method according to one of the preceding claims, in which the second composition (ii) comprises between 0.04 and 5% by weight of ferulic acid or one of its derivatives, relative to the total weight of the composition (ii), preferably from 0.5 to 4% by weight, preferably from 1 to 3% by weight.

6. Method according to one of the preceding claims, in which the second composition (ii) comprises, relative to the total weight of the composition (ii), at least 20% by weight, preferably at least 30% by weight, preferably at least 40% by weight, preferably at least 50% by weight, preferably at least 60% by weight, preferably at least 70% by weight, preferably at least 80% by weight, preferably at least 85% by weight, preferably at least 90% by weight, preferably at least 95% by weight, preferably at least 98% by weight of glycol preferably chosen from polyols having from 2 to 20 carbon atoms, such as glycerol, diglycerol, propylene glycol, isoprene glycol, dipropylene glycol, butylene glycol, caprylyl glycol, hexylene glycol, 1,3-propanediol, pentylene glycol, polyethylene glycols having from 2 to 200 ethylene oxide units and mixtures thereof, preferably the glycol is dipropylene glycol.

7. Method according to one of the preceding claims, in which the cosmetic composition obtained has a pH of between 4 and 8, preferably between 5 and 7, preferably a pH of 6.

8. Process for caring for keratin materials, in particular the skin, which comprises (1) the process for preparing a cosmetic composition according to one of the preceding claims, then (2) the application of the cosmetic composition to the keratin materials, in particular the skin.

9. Care method according to claim 8, in which step (2) of applying the cosmetic composition takes place at the latest one month after step (1) of preparing said composition.

10. Stable cosmetic composition comprising, relative to the total weight of the composition: - from 0.1 to 15% by weight of ascorbic acid or one of its derivatives, and - from 0.01 to 1% by weight of ferulic acid or one of its derivatives, said composition having a pH of between 4 and 8, preferably between 5 and 7, preferably of pH 6.

11. Cosmetic composition according to claim 10, characterized in that it is stable at room temperature, i.e. between 20°C and 25°C.

12. Kit for the care and / or treatment of keratin materials, in particular the skin, comprising (i) a first aqueous composition comprising ascorbic acid or one of its derivatives and polyquaternium-67, and (ii) a second composition comprising, in at least one glycol, ferulic acid or one of its derivatives.