Composition containing valerian

Abstract

To provide a composition containing valerian with reduced unpleasant odor and a method for reducing the unpleasant odor derived from the valerian.SOLUTION: A method includes adding enzymatically decomposed lecithin and / or cyclodextrin to valerian, which reduces unpleasant odor derived from the valerian.SELECTED DRAWING: None

Description

[Technical field]

[0001] The present invention relates to a valerian-containing composition having reduced unpleasant odor. [Background technology]

[0002] Valerian (Valeriana officinalis) is a perennial plant of the Valeriana genus in the family Valeriaceae, and is also called valeriana, valerian officinalis, or valerian grass. Extracts of the roots and rhizomes of valerian contain valerenic acid, which is known to be effective in improving insomnia and anxiety.

[0003] On the other hand, valerian has a strong, unpleasant odor that is problematic when ingesting valerenic acid, a functional component of valerian, and reducing the odor is an issue in increasing its versatility. Patent Document 1 discloses an oral composition that contains 10% or more by weight of valerian powder and Cnidium officinalis powder, which contains a high content of valerian powder but has a reduced strong, unpleasant odor that is characteristic of valerian powder. [Prior art documents] [Patent documents]

[0004] [Patent Document 1] JP 2023-095489 A Summary of the Invention [Problem to be solved by the invention]

[0005] The present invention provides a valerian-containing composition having reduced unpleasant odor and a method for reducing the unpleasant odor derived from valerian. [Means for solving the problem]

[0006] The inventors discovered that the unpleasant odor derived from valerian can be reduced by adding enzymatically decomposed lecithin and / or cyclodextrin to valerian, and thus completed the present invention.

[0007] That is, the present invention relates to the following aspects [1] to [7]. [1] A valerian-containing composition comprising valerian and enzymatically decomposed lecithin and / or cyclodextrin. [2] The valerian-containing composition described in [1], which contains 1 to 200 parts by weight of enzymatically decomposed lecithin and / or 10 to 300 parts by weight of cyclodextrin per 100 parts by weight of valerian. [3] A valerian-containing composition according to [1] or [2], in which the unpleasant odor derived from valerian is reduced. [4] A method for reducing unpleasant odors derived from valerian, characterized by combining enzymatically hydrolyzed lecithin and / or cyclodextrin with valerian. [5] A method for reducing an unpleasant odor derived from valerian described in [4], comprising blending 1 to 200 parts by weight of enzymatically decomposed lecithin and / or 10 to 300 parts by weight of cyclodextrin per 100 parts by weight of valerian. [6] A method for reducing the unpleasant odor derived from valerian described in [4] or [5], which reduces the unpleasant odor by suppressing the volatilization of isovaleric acid. [7] A food, beverage, or pharmaceutical product comprising the valerian-containing composition described in any one of [1] to [3]. Effect of the Invention

[0008] INDUSTRIAL APPLICABILITY The present invention makes it possible to provide a valerian-containing composition in which the unpleasant odor derived from valerian has been reduced, making it possible to use the composition in a wide range of products. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0009] In the present invention, the unpleasant odor derived from valerian is reduced by blending enzymatically decomposed lecithin and / or cyclodextrin with valerian, and the valerian-containing composition of the present invention contains valerian and enzymatically decomposed lecithin and / or cyclodextrin, and preferably contains enzymatically decomposed lecithin and cyclodextrin.

[0010] The valerian according to the present invention is a dried product of the root or rhizome of valerian, such as valerian powder, which is used as a herbal medicine.Furthermore, it may be a valerian extract, such as a commercially available valeriana root dry extract obtained by drying an extract extracted from valerian.

[0011] The enzymatically decomposed lecithin described in the present invention is not particularly limited as long as the valerian-containing composition of the present invention can be obtained, but examples thereof include enzymatically decomposed lecithin obtained by decomposing soybean lecithin, sunflower lecithin, egg yolk lecithin, etc. with phospholipase A1 or A2, which is a type of lecithin decomposition enzyme, and commercially available products may be used. The phospholipid content in the enzymatically decomposed lecithin is preferably 40% by weight or more, more preferably 60% by weight or more, and particularly preferably 80% by weight or more. The content of the enzymatically decomposed lecithin relative to 100 parts by weight of valerian is preferably 1 to 200 parts by weight, more preferably 2 to 100 parts by weight, and even more preferably 3 to 80 parts by weight, and the unpleasant odor derived from valerian can be reduced by adding the enzymatically decomposed lecithin.

[0012] The cyclodextrin described in the present invention may be any dextrin having a cyclic structure produced by enzymatic conversion of starch, and is preferably a cyclodextrin having good solubility that mainly contains α-cyclodextrin or γ-cyclodextrin, and a commercially available product can be used. The content of cyclodextrin relative to 100 parts by weight of valerian is preferably 10 to 300 parts by weight, more preferably 20 to 200 parts by weight, and even more preferably 30 to 100 parts by weight, and the unpleasant odor derived from valerian can be reduced by adding enzymatically decomposed lecithin.

[0013] The valerian-containing composition of the present invention can be produced by blending valerian with enzymatically decomposed lecithin and / or cyclodextrin, and by mixing and dissolving valerian, enzymatically decomposed lecithin and / or cyclodextrin, and water, and further drum drying, air drying, spray drying, vacuum drying, and / or freeze drying, etc., may be carried out to produce a concentrated or dried product, and a powder is preferable, and a granule product can be produced using a granulator, etc., if necessary. Also, an excipient such as dextrin may be added and dried.

[0014] In the present invention, by blending enzymatically hydrolyzed lecithin and / or cyclodextrin with valerian, the unpleasant odor derived from valerian can be reduced and the volatilization of isovaleric acid can be suppressed. For example, in a valerian-containing composition, the unpleasant odor can be reduced by suppressing the volatilization of isovaleric acid.

[0015] As described above, the valerian-containing composition of the present invention contains valerian and enzymatically decomposed lecithin and / or cyclodextrin, thereby reducing the unpleasant odor derived from valerian, and is a versatile valerian-containing composition that can be widely used in various foods and beverages such as functional foods and supplements, medicines, quasi-drugs, etc. The content of valerenic acid in the valerian-containing composition is not particularly limited, but is preferably 0.01 to 5% by weight, more preferably 0.02 to 3% by weight, and even more preferably 0.03 to 1% by weight. The amount of the valerian-containing composition added to various foods and beverages, medicines, quasi-drugs, etc. is not particularly limited, but is preferably 0.01 to 50% by weight, more preferably 0.05 to 30% by weight, and even more preferably 0.1 to 10% by weight. EXAMPLES

[0016] The present invention will be described in detail below with reference to examples, but the present invention is not limited to the following examples. In the present invention, all % is by weight unless otherwise specified.

[0017] [Example 1] Valerian-containing compositions (valerenic acid content: 0.065%) of Examples 1-1 to 1-6 were obtained by mixing and dissolving the valerian extract Valeriana root dried extract (valerenic acid content: 0.65%, Ask Pharmaceutical Co., Ltd.) as valerian, enzymatically hydrolyzed lecithin SLP (registered trademark) White Lyso (phospholipid content: 92% or more, Tsuji Oil Mills Co., Ltd.), cyclodextrin Dixie Pearl (registered trademark) α-100 (α-cyclodextrin content: 98% or more, Shiozuiko Sugar Refining Co., Ltd.) or Dixie Pearl (registered trademark) γ-100 (γ-cyclodextrin content: 98% or more, Shiozuiko Sugar Refining Co., Ltd.) as cyclodextrin, and tap water in the formulation shown in Table 1.

[0018] [Comparative Example 1] Using the formulation shown in Table 1, a valerian-containing composition (valerenic acid content: 0.065%) as Comparative Product 1 was obtained in the same manner as in Example 1.

[0019] [Evaluation test] For the valerian-containing compositions of the working samples 1-1 to 1-6 and the comparative sample 1, the peak area ratio (isovaleric acid / IS) of isovaleric acid, one of the unpleasant odor components, to the internal standard substance (IS: cyclohexanol) was calculated using the solid phase microextraction gas chromatography mass spectrometry (SPME / GC / MS) described below. In addition, for the aqueous solutions in which each valerian-containing composition was added at 1% to tap water, the unpleasant odor intensity was sensorily evaluated on a five-point scale, with 5 being the strongest unpleasant odor and 1 being the weakest unpleasant odor. The results are shown in Table 1.

[0020] <Solid-phase microextraction gas chromatography mass spectrometry> SPME fiber: DVB / PDMS (Agilent Technologies) SPME extraction conditions: 50℃, 30 minutes Injection conditions: 260℃, splitless Column: DB-WAX (30 m × φ0.25 mm, film thickness 0.25 μm) (Agilent Technologies) Column temperature: 40°C → 3°C / min → 230°C (held for 10 minutes)

[0021] [Table 1]

[0022] As shown in Table 1, the valerian-containing compositions of the implementation products 1-1 to 1-3 containing valerian extract and enzymatically decomposed lecithin, the valerian-containing compositions of the implementation products 1-4 and 1-5 containing valerian extract and cyclodextrin, and the valerian-containing compositions of the implementation products 1-6 containing valerian extract, enzymatically decomposed lecithin and cyclodextrin had smaller peak area ratios to the internal standard substance (IS: cyclohexanol) of isovaleric acid and weaker unpleasant odors than the valerian-containing composition of the comparative product 1 consisting only of valerian extract. Therefore, it was found that the volatilization of isovaleric acid in the valerian extract was suppressed by the enzymatically decomposed lecithin and / or cyclodextrin, and a valerian-containing composition with reduced unpleasant odors was obtained.

[0023] [Example 2] Valerian extract, valerian root dried extract (valerenic acid content: 0.65%), enzymatically hydrolyzed lecithin, SLP (registered trademark) White Lyso (phospholipid content: 92% or more), cyclodextrin, Dixie Pearl (registered trademark) α-100 (α-cyclodextrin content: 98% or more) or Dixie Pearl (registered trademark) γ-100 (γ-cyclodextrin content: 98% or more), and tap water were mixed and dissolved in the formulation shown in Table 2, and then dried / powdered using a spray dryer to obtain valerian-containing composition (valerenic acid content: 0.32%), Example 2-1 or 2-2.

[0024] [Comparative Example 2] Valerian extract, valerian root dried extract, dextrin, Sandec (registered trademark) #100 (Sanwa Starch Industry Co., Ltd.) as an excipient, and tap water were mixed and dissolved in the formulation shown in Table 2, and then dried / powdered using a spray dryer to obtain a valerian-containing composition (valerenic acid content: 0.32%) as comparison product 2.

[0025] For the valerian-containing compositions of the embodiment products 2-1, 2-2 and the comparison product 2, the peak area ratio to the internal standard substance of isovaleric acid was calculated according to the above evaluation test, and the unpleasant odor was evaluated. The results are shown in Table 2.

[0026] [Table 2]

[0027] As shown in Table 2, the valerian-containing compositions of the embodiment products 2-1 and 2-2, which contain valerian extract, enzymatically decomposed lecithin and cyclodextrin, have a smaller peak area ratio to the internal standard substance of isovaleric acid and a weaker unpleasant odor than the valerian-containing composition of the comparison product 2, which is made of valerian extract and dextrin. Therefore, it was found that by powdering the valerian extract using enzymatically decomposed lecithin and cyclodextrin, the volatilization of isovaleric acid in the valerian extract is suppressed, and a powdered valerian-containing composition with reduced unpleasant odor can be obtained.

Claims

1. A valerian-containing composition comprising valerian and enzymatically decomposed lecithin and / or cyclodextrin.

2. The valerian-containing composition according to claim 1, comprising 1 to 200 parts by weight of enzymatically decomposed lecithin and / or 10 to 300 parts by weight of cyclodextrin per 100 parts by weight of valerian.

3. The valerian-containing composition according to claim 1 or 2, which has a reduced unpleasant odor derived from valerian.

4. A method for reducing unpleasant odors derived from valerian, comprising blending enzymatically decomposed lecithin and / or cyclodextrin with valerian.

5. The method for reducing unpleasant odors derived from valerian according to claim 4, comprising blending 1 to 200 parts by weight of enzymatically decomposed lecithin and / or 10 to 300 parts by weight of cyclodextrin with respect to 100 parts by weight of valerian.

6. The method for reducing the unpleasant odor derived from valerian according to claim 4 or 5, wherein the unpleasant odor is reduced by suppressing the volatilization of isovaleric acid.

7. A food, drink, or medicine comprising the valerian-containing composition according to claim 1 or 2.

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