Deformation member, method for manufacturing deformation member, mask, capsule and catheter

Abstract

To provide a deformation member that can be more easily produced.SOLUTION: A deformation member 10 is a plate-shaped deformation member made of a swelling gel that swells by swelling a liquid, and a plurality of grooves 11 extend in parallel on one surface thereof.SELECTED DRAWING: Figure 1

Description

Technical Field

[0001] The present invention relates to a deformable member, a method for manufacturing the deformable member, a mask, a capsule, and a catheter.

Background Art

[0002] In conventional 3D modeling, an object was assumed not to deform during use and was treated as a rigid body. In contrast, a new concept called 4D printing was proposed by Skylar Tibbits. In 4D printing, an object changes its shape, etc. over time according to the surrounding environment, and various studies are being conducted in the field of soft robotics.

[0003] Non-Patent Document 1 discloses a plate-shaped composite material. By wetting this composite material, it bends toward the gel material with a low swelling rate and functions as a driving element for deforming an object.

Prior Art Documents

Non-Patent Documents

[0004]

Non-Patent Document 1

Summary of the Invention

Problems to be Solved by the Invention

[0005] The deformable member described in Non-Patent Document 1 performs 3D modeling by curing a gel solution with ultraviolet rays using a 3D printer. At this time, by forming a gradient in the crosslinking density in the thickness direction, the swelling rate is changed. Therefore, in order to form a gradient in the crosslinking density, it is necessary to control the irradiation of the UV laser, and there is a problem that many parameters must be set, which is time-consuming.

[0006] The present invention has been made in view of the above problems, and an object thereof is to provide a deformable member that can be manufactured more easily.

Means for Solving the Problems

[0007] As a result of intensive studies, the inventors have found that by providing a plurality of grooves in parallel on one surface of a flat plate-shaped wet gel, the flat plate-shaped gel is curved so that the surface on the side where the grooves are formed faces inward. The present invention is based on this finding.

[0008] According to one aspect of the present invention, there is provided a plate-shaped deformable member made of a swellable gel that swells by impregnating with a liquid, wherein a plurality of grooves extend in parallel on one surface.

[0009] According to this aspect, when the swellable gel swells, it curves toward the side where the groove is formed. And the curvature of the swellable gel according to this aspect is due to the shape rather than the gradient of the crosslinking density of the gel, so that the deformable member can be easily manufactured. When such a deformable member is manufactured by, for example, a 3D printer, since the crosslinking density is constant, there is no need to set complicated parameters. Also, even without using a 3D printer, it is possible to manufacture using a mold. Furthermore, the deformable member described in Non-Patent Document 1 has different elasticities in part because the crosslinking density varies from part to part, but according to the deformable member of this aspect, since the crosslinking density is constant, the elasticity becomes uniform and it becomes easier to control the deformation by changing the shape of the groove. Furthermore, the deformable member described in Non-Patent Document 1 has different colors (for example, transparency) in part because the crosslinking density varies from part to part, but according to this aspect, since the crosslinking density is constant, there is no difference in the crosslinking density between parts and the color becomes constant.

[0010] According to one aspect of the present invention, the deformable member is composed of a swellable gel having a constant single-layer crosslinking density.

[0011] According to one aspect of the present invention, the plurality of grooves extend in parallel.

[0012] According to one aspect of the present invention, the groove has a polygonal cross-sectional shape.

[0013] According to one aspect of the present invention, the groove has a rectangular or hexagonal cross-sectional shape that is symmetric about the left and right.

[0014] According to one aspect of the present invention, the ratio (A / C) of the width A of the groove to the interval C between the grooves is 0.5 or more, and the ratio (B / F) of the depth B of the groove to the thickness F of the deformable member is 0.5 or more.

[0015] According to one aspect of the present invention, the deformation speed per unit length of the deformable member is 0.06 degrees / sec·mm or more.

[0016] According to one aspect of the present invention, the Young's modulus of the swellable gel is 50 to 100 kPa.

[0017] According to one aspect of the present invention, the swellable gel includes a first polymer, a photoinitiator, a monomer that forms a second polymer by polymerization using the photoinitiator, and a light absorber, and the first polymer and the second polymer constitute the gel.

[0018] According to one aspect of the present invention, there is provided a method for manufacturing a plate-shaped deformable member made of a swellable gel that swells by impregnating a liquid, wherein a plurality of grooves are arranged in parallel on one surface of the deformable member, and a step of forming an inversion mold having a concave portion obtained by inverting a mold using a 3D printer, a step of filling the inversion mold with an inversion mold material to form a mold having a convex portion corresponding to the groove of the deformable member, and a step of filling the mold with a material and crosslinking the material to form the deformable member.

[0019] According to one aspect of the present invention, the mold includes silicone.

[0020] According to one aspect of the present invention, there is provided a mask including at least a part of the above-described deformable member.

[0021] According to one aspect of the present invention, there is provided a capsule including at least a part of the above-described deformable member, accommodating a drug in an internal space, and opening the internal space to the outside when the deformable member deforms.

[0022] According to one aspect of the present invention, there is provided a catheter including at least a part of the above-described deformable member, and expanding outward when the deformable member gets wet while being disposed in a blood vessel.

Advantages of the Invention

[0023] According to the present invention, it is possible to provide a deformable member that can be manufactured more easily.

Brief Description of the Drawings

[0024]

Figure 1

Figure 2

Figure 3

Figure 4

Figure 5

Figure 6

Figure 7

Figure 8

Figure 9

Figure 10

Figure 11

Figure 12

Mode for Carrying Out the Invention

[0025] <Deformable Member According to the First Embodiment> Hereinafter, the deformable member according to the first embodiment of the present invention will be described. FIGS. 1 and 2 show a deformable member according to the first embodiment, FIG. 1 is a perspective view, and FIG. 2 is a side view. The deformable member 10 of the present embodiment is made of a swellable gel formed in an elongated flat plate shape. As shown in FIGS. 1 and 2, the deformable member 10 has a plurality of grooves 11 formed on the surface (one surface). The plurality of grooves 11 are formed in parallel in the longitudinal direction and each extends in the width direction. The deformable member 10 of the present embodiment has a single-layer structure made of one type of swellable gel. Further, the swellable gel constituting the deformable member has a substantially constant crosslinking density regardless of the position.

[0026] These grooves 11 are defined between adjacent protrusions 12 formed by arranging a plurality of protrusions 12 in the longitudinal direction and extending in the width direction. In the present embodiment, the cross-sectional shape of the groove 11 is a rectangular shape that is symmetric about the left and right, and the cross-sectional shape of the protrusion 12 is also a rectangular shape. The groove 11 and the protrusion 12 each extend in the width direction perpendicular to the longitudinal direction of the deformable member 10. The width A and the depth B of these plurality of grooves 11 are constant, and the interval C between adjacent grooves 11 is constant.

[0027] The deformable member 10 of the present embodiment swells when immersed in a liquid such as water. The swelling here means absorbing a solvent and expanding in volume in a state of being immersed in a liquid. Further, the swelling gel in the present invention means a gel having such a swelling property. Note that the solvent for swelling the swelling gel may be any liquid, not limited to only water, and examples include liquids containing moisture, monohydric alcohols such as ethanol, and polyhydric alcohols. Note that water may contain an electrolyte component.

[0028] In the present embodiment, the grooves 11 are formed only on the surface. Thereby, by swelling the deformable member 10, the portion on the back surface side expands in the longitudinal direction. On the other hand, since the grooves 11 are formed on the surface of the deformable member 10, in the portion on the surface side, although the protrusions 12 expand in the longitudinal direction of the deformable member 10, they can enter into the grooves 11. For this reason, the portion on the back surface side expands greatly with respect to the portion on the surface side, and as a result, the deformable member 10 bends toward the surface side.

[0029] In addition, in this embodiment, the case where the deformation member 10 is a flat member is described. However, the present invention is not limited to this. As long as the deformation member has a shape with a front surface and a back surface (hereinafter, such a shape is referred to as a plate shape), it may have a curved shape or the like. For example, it is also possible to use a deformed member in a plate shape with rounded edges. Further, the planar shape of the deformation member 10 is not limited to a rectangular shape as in this embodiment, and may be, for example, a circular shape, an elliptical shape, or the like. When the deformation member is flat as in this embodiment, the deformation member becomes curved from flat by swelling. On the other hand, when the deformation member has rounded edges and a groove is formed on the outer side of the curvature, the deformation member deforms so as to approach flatness when it swells.

[0030] Also, in this embodiment, the case where the grooves 11 extend in parallel is described. However, the arrangement of the grooves 11 is not limited to this, and the plurality of grooves 11 may extend in parallel. The fact that the plurality of grooves 11 extend in parallel as used herein means that the plurality of grooves 11 are arranged side by side. The shape of the grooves 11 is not limited, and the arrangement may generally extend in the same direction. For example, arc-shaped grooves may extend concentrically, or zigzag-shaped grooves may extend at intervals.

[0031] Also, in this embodiment, the case where the grooves 11 extend in the same direction in parallel is described. However, the present invention is not limited to this, and a plurality of grooves 11 may be formed in a lattice shape. Thereby, the deformation member can be deformed three-dimensionally.

[0032] Also, in this embodiment, the case where the grooves 11 are formed only on one surface is described. However, the present invention is not limited to this, and grooves may be formed on both surfaces. In this case, for example, by narrowing the interval between the grooves on one surface and forming a large number of grooves, it is possible to cause curvature when swelling.

[0033] By changing the shape and arrangement of the grooves in this way, it is possible to control the curvature and deformation shape of the deformation member during deformation.

[0034] <Dimensions of the deformation member> The preferred dimensions of the deformation member 10 of this embodiment are as follows.

[0035] The length D and width E of the deformation member 10 are not particularly limited. As an example, the length D can be 50 mm and the width E can be 10 mm. The thickness F (FIG. 1) of the deformation member 10 is preferably 2 to 6 mm, more preferably 3 to 5 mm, and most preferably 4 mm. The width A of the groove 11 of the deformation member 10 is preferably 0.5 to 3 mm, more preferably 1.1 to 2 mm. The depth B of the groove 11 of the deformation member 10 is preferably 0.5 to 5 mm, more preferably 1 to 3 mm. The interval C between the grooves 11 of the deformation member 10 is preferably 1 to 15 mm, more preferably 2 to 10.5 mm. The ratio (A / C) of the width A to the interval C of the groove 11 of the deformation member 10 is preferably 0.1 to 0.7, more preferably 0.2 to 0.6. In particular, the ratio (A / C) of the width A to the interval C of the groove 11 of the deformation member 10 is preferably 0.5 or more. The ratio (B / F) of the depth B of the groove 11 to the thickness F of the deformation member 10 is preferably 0.1 to 0.9, more preferably 0.5 to 0.8. In particular, the ratio (B / F) of the depth B of the groove 11 to the thickness F of the deformation member 10 is preferably 0.5 or more. Also, the ratio of the upper surface area (the area of the portion other than the groove 11) to the lower surface area of the deformation member 10 is preferably 0.3 to 0.9, more preferably 0.3 to 0.8. In addition, when the deformation member is curved in an arc shape, the width A and the interval C may be, for example, the lengths on the arc along the surface where the groove is formed, and the depth C may be the length in the radial direction. Also, when the deformation member is curved in an arc shape, the length D may be the circumferential length at the center in the thickness direction. Also, when the shape of the groove 11 is a polygon or the like, the width A may be the average width of the entire groove, or since the influence of the width on the surface is large, it may be the width on the surface. In this case, it is preferable that at least the average width of the entire groove and the width on the surface are within the above ranges, and it is more preferable that both are within the above width ranges.

[0036] The elasticity (Young's modulus) of the swelling gel constituting the deformation member 10 is preferably 50 to 100 kPa. Further, as the crosslinking density of the swelling gel constituting the deformation member 10, it is 4.42×10 21 ~8.85×10 21 (m -3 ) is preferable.

[0037] If the area occupied by the groove 11 in the deformation member 10 is too small, the deformation member 10 approaches a flat plate shape, so the deformation force becomes small. Also, when the area occupied by the groove 11 in the deformation member 10 is too large, the deformation member 10 approaches a flat plate shape, so the deformation force becomes small. Also, if the depth of the groove 11 is too small, the deformation member 10 approaches a flat plate shape, so the deformation force becomes small. On the other hand, when the depth of the groove 11 is too large, the thickness of the bottom part where the groove of the deformation member 10 is not formed becomes too small, and the deformation force becomes small. When the depth of the groove of the deformation member 10 is too large, even with a slight deformation, the tip of the adjacent protrusion 12 of the deformation member 10 comes into contact, and the deformation does not progress. Therefore, in order to sufficiently deform the deformation member 10 when wet, it is preferable that the dimensions (ratio) of the groove 11 of the deformation member 10 be within the above-mentioned range. In this embodiment, the intervals, widths, and depths of the plurality of grooves 11 are constant, but the present invention is not limited to this, and the intervals, widths, and depths of the grooves 11 may be partially changed. In this case, it is preferable that the intervals, widths, and depths of at least some of the grooves 11 be within the above-mentioned range. By partially changing the intervals, widths, and depths of the grooves 11, the magnitude of the deformation and the speed of the deformation during swelling can be partially changed.

[0038] <Deformation speed> FIG. 3 is a diagram for explaining the bending angle of the deformation member. As shown in FIG. 3, the deformation member 10 is deformed into a substantially arc shape by swelling, and hardly deforms when the deformation member 10 is sufficiently swollen. In the present invention, the bending angle θ of the arc-shaped deformation member 10 is divided by the time taken for the deformation, and the bending angle per unit time is defined as the deformation speed. Further, since the deformation angle θ of the deformation member depends on the total length of the deformation member, the deformation speed was divided by the total length of the deformation member 10 to calculate the deformation speed per unit length of the deformation member.

[0039] The deformation speed of the deformation member 10 preferably deforms from 30 degrees to 120 degrees per 10 seconds when the total length of the deformation member 10 is 50 mm. That is, when the total length is 50 mm, the deformation speed is preferably 3 degrees / sec (=30 / 10) or more and 12 degrees / sec (=120 / 10) or less. Further, when the total length of the deformation member 10 is 50 mm, the deformation speed is more preferably 6 degrees / sec or more and 12 degrees / sec.

[0040] Furthermore, the deformation speed per unit length of the deformation member is preferably 0.06 degrees / sec·mm (=3 / 50) or more and 0.24 degrees / sec·mm (=12 / 50) or less, and more preferably 0.12 degrees / sec·mm or more and 0.24 degrees / sec·mm or less.

[0041] As swelling progresses, the deformation speed decreases, but it is preferable that at least the deformation speed is within the above range in the state where it is the fastest.

[0042] <Swelling gel used for the deformation member> As the gel material that can be used as the swelling gel used for the deformation member 10, any gel having water absorption and swelling by absorbing water can be used. As the swelling gel used for the deformable member 10, for example, a polymer using acrylic acid (Acrylic acid (AA)) as a monomer can be used. After adding a crosslinking agent, a photopolymerization initiator, sodium hydroxide, etc. to acrylic acid (Acrylic acid (AA)) and mixing them, the swelling gel can be produced by irradiating with UV.

[0043] As the monomer, instead of acrylic acid (Acrylic acid (AA)), methacrylic acid, methyl methacrylate, diacid acrylate, di-tert-butyl acrylate, 2-ethylhexyl acrylate, diethylene glycol diacrylate, ethyl acrylate, n-butyl acrylate, hydroxypropyl acrylate, diethylene glycol diacrylate, dimethylaminoethyl acrylate can be used.

[0044] As the crosslinking agent, for example, N, N-methylene bis acrylamide (MBAA) can be used. As the photopolymerization initiator, diphenyl (2,4,6-trimethyl benzoyl)phosphine oxide (TPO) can be used.

[0045] After adding a monomer, a crosslinking agent, and a photoinitiator to water and stirring, further add sodium hydroxide to water to prepare a pregel solution, and the above-mentioned swellable gel can be prepared by irradiating this pregel solution with UV light.

[0046] Furthermore, as the swellable gel, for example, the hydrogel described below can be used. The hydrogel contains a first polymer, a photoinitiator, a monomer that forms a second polymer by polymerization using this photoinitiator, and a light absorber, and is composed of the first polymer and the second polymer.

[0047] The first polymer is obtained by using, as a raw material monomer, for example, a sodium 2-acrylamido-2-methyl-1-propanesulfonate solution (NaAMPS), 2-acrylamido-2-methylpropanesulfonic acid (AMPS), acrylamide (AAm), acrylic acid (AA), methacrylic acid, N-isopropylacrylamide, vinylpyridine, hydroxyethyl acrylate, vinyl acetate, dimethylsiloxane, styrene (St), methyl methacrylate (MMA), trifluoroethyl acrylate (TFE), styrenesulfonic acid (SS), or dimethylacrylamide such as N,N-dimethylacrylamide.

[0048] Alternatively, it may be obtained by using a fluorine-containing monomer such as 2,2,2-trifluoroethyl methyl acrylate, 2,2,3,3,3-pentafluoropropyl methacrylate, 3-(perfluorobutyl)-2-hydroxypropyl methacrylate, 1H,1H,9H-hexadecafluorononyl methacrylate, 2,2,2-trifluoroethyl acrylate, 2,3,4,5,6-pentafluorostyrene, or vinylidene fluoride.

[0049] Furthermore, polysaccharides such as gellan, hyaluronic acid, carrageenan, chitin, or alginic acid, or proteins such as gelatin or collagen may be used as the first polymer.

[0050] The first polymer preferably has a network structure. The first polymer is also preferably fine particles.

[0051] The monomer for forming the second polymer can be polymerized using a photoinitiator, for example, 2-acrylamido-2-methylpropanesulfonic acid (AMPS), N,N-dimethylacrylamide (DMAAm), 2-(dimethylamino)ethyl methacrylate, lauryl acrylate (LA), stearyl acrylate (SA), acrylic acid (AA), methacrylic acid, styrenesulfonic acid, or salts thereof, such as sodium 2-acrylamido-2-methylpropanesulfonate, sodium acrylate, sodium styrenesulfonate, etc.

[0052] Preferred examples of the second polymer include polyacrylamide-2-methylpropanesulfonic acid polymerized with 2-acrylamido-2-methylpropanesulfonic acid (AMPS) as a monomer, sodium polyacrylamide-2-methylpropanesulfonate polymerized with sodium 2-acrylamido-2-methylpropanesulfonate (NaAMPS) as a monomer, poly-N,N-dimethylacrylamide (PDMAAm) polymerized with N,N-dimethylacrylamide (DMAAm) as a monomer, and the like.

[0053] The second polymer preferably has a network structure.

[0054] Furthermore, the hydrogel composed of the first polymer and the second polymer preferably has a structure in which the second polymer penetrates into the network structure of the first polymer. Moreover, it preferably has a network structure in which the first polymer and the second polymer penetrate into each other.

[0055] The photoinitiator may be any substance that can initiate the polymerization of the above monomers by light such as ultraviolet light or visible light. For example, it may be α-ketoglutaric acid, benzophenone, acetophenone benzyl, benzyldimethyl ketone, benzoin, benzoin methyl ether, benzoin ethyl ether, benzoin isopropyl ether, dimethoxyacetophenone, dimethoxyphenylacetophenone, diethoxyacetophenone, diphenyldisulfite, methyl orthobenzoylbenzoate, ethyl 4-dimethylaminobenzoate, 2,4-diethylthioxanthone, 2-methyl-1-[4-(methyl)phenyl]-2-morpholinopropanone-1, tetra(t-butylperoxycarbonyl)benzophenone, benzyl, 2-hydroxy-2-methyl-1-phenyl-propan-1-one, 4,4-bisdiethylaminobenzophenone, 2,2'-bis(2-chlorophenyl)-4,5,4’,5’-tetraphenyl-1,2’-biimidazole, etc.

[0056] In this specification, the "light absorber" means a substance that absorbs light and converts it into thermal energy, and does not include substances that emit light like a fluorescent brightener even if they absorb light. The ultraviolet absorber used in the present invention may be a benzotriazole-based one such as KEMISORB 71, KEMISORB 73, KEMISORB 74, KEMISORB 79, KEMISORB 279 manufactured by Chemipro Kasei Co., Ltd., a benzophenone-based one such as KEMISORB 10, KEMISORB 11, KEMISORB 11S, KEMISORB 12, KEMISORB 111, or a triazine-based ultraviolet absorber such as KEMISORB 102. Benzophenone-based ultraviolet absorbers are particularly preferred.

[0057] In the above hydrogel, the light absorber is preferably contained in an amount of 1:3 to 3:1 in molar ratio with respect to the photoinitiator.

[0058] The above hydrogel may further contain a crosslinking agent for crosslinking the second polymer. As the crosslinking agent, a polyfunctional vinyl monomer having two or more radically polymerizable unsaturated groups can be used. Divinyl compounds such as N,N'-methylenebisacrylamide (MBAA), ethylene glycol dimethacrylate (EDMA), and N,N'-diethylene glycol dimethacrylate (DEGDMA) can be preferably used.

[0059] The method for preparing the above hydrogel is not particularly limited, and for example, the following method can be adopted.

[0060] That is, first, the first monomer, crosslinking agent, and photoinitiator are mixed at a predetermined molar ratio (for example, 1:4:0.1), and bubbling is performed using nitrogen for about 10 minutes. Then, UV light is irradiated for about 7 hours to produce the first polymer. The produced first polymer is dried and pulverized into fine particles.

[0061] Next, the second monomer, crosslinking agent, and photoinitiator are mixed at a predetermined molar ratio (for example, 1:0.01:0.01), and a light absorber such as an ultraviolet absorber is mixed therein at a predetermined molar ratio to prepare a mixed solution for forming the second polymer. The prepared mixed solution and the first polymer fine particles are mixed so that the weight ratio becomes 30:1, and the first polymer and the second polymer are irradiated with light to prepare a gel material that constitutes a gel.

[0062] In a 3D gel printer, the gel material before UV irradiation can be placed in a bathtub-shaped container, and only the irradiated portion by UV laser irradiation is radically polymerized and gelled to produce a swellable gel.

[0063] <Manufacturing method of the deformable member> Hereinafter, the manufacturing method of the deformable member will be described. FIG. 4 is a diagram for explaining the manufacturing method of the deformable member according to the first embodiment. First, as shown in FIG. 4(A), an inversion mold 100 for manufacturing a molding die is molded. The inversion mold 100 is formed by 3D printing. The inversion mold 100 is for manufacturing the molding die described later, and has a container portion 110 having a side wall, a front wall, a rear wall, and a bottom plate, and a convex portion 120 formed in the container portion 110. The convex portion 120 has a shape corresponding to the shape of the deformable member 10 finally manufactured. A space (recess) 130 corresponding to the shape of the molding die 140 is formed between the container portion 110 and the convex portion 120. The inversion mold 100 can be manufactured using, for example, an ABS resin, a PLA resin, or the like.

[0064] Next, the molding die 140 is manufactured using the inversion mold 100. The recess 130 of the inversion mold 100 is filled with a base polymer blended with a crosslinking agent, and further, a vulcanizing agent is added and heated. Thereby, the base polymer is crosslinked, and the molding die 140 can be manufactured. Then, the molding die 140 is removed from the inversion mold 100. The molding die is preferably formed of a flexible material such as a material containing silicone. Thereby, when the deformable member is released from the molding die, damage to the deformable member can be suppressed.

[0065] FIG. 4(B) shows the manufactured molding die. As shown in FIG. 4(B), the molding die 140 has a container portion 150 having a side wall, a front wall, a rear wall, and a bottom plate, and a convex portion 160 formed on the bottom surface. The convex portion 160 has a shape corresponding to the groove 11 of the deformable member 10. A space (recess) 170 corresponding to the shape of the deformable member 10 is formed between the container portion 150 and the convex portion 160.

[0066] Next, the deformable member 10 is manufactured using the molding die 140. The recess 170 of the molding die 140 is filled with the gel material prepared as described above, and the gel material is irradiated with a UV laser. The portion irradiated with the UV laser undergoes radical polymerization and gelation. Then, the deformable member 10 can be manufactured by releasing the gelled material from the molding die 140.

[0067] <Deformable Member of the Second Embodiment> The following describes the deformation member of the second embodiment. The deformation member of the second embodiment is different from that of the first embodiment in that the cross-sectional shape of the groove is hexagonal.

[0068] FIGS. 5 and 6 show the deformation member according to the second embodiment, FIG. 5 is a perspective view, and FIG. 6 is a side view. As shown in FIGS. 5 and 6, the deformation member 201 has a plurality of grooves 211 formed on the surface (one surface). The plurality of grooves 211 are arranged in parallel in the longitudinal direction and extend in the width direction. The cross-sectional shape of the groove 211 is a vertically long hexagonal shape, which is symmetric about the vertical and horizontal axes. These grooves 211 are formed by the protrusions 212 having a shape such that the width narrows at an intermediate height between the grooves 211 extending in the width direction. The widths A and depths B of the plurality of grooves 211 are constant, and the intervals C between the plurality of grooves 211 are constant.

[0069] Also in this embodiment, the grooves 211 are formed only on the surface. As a result, when the deformation member 201 is swollen, the portion on the back side expands in the longitudinal direction. On the other hand, since the grooves 211 are formed on the surface, in the portion on the surface side, although the protrusions 212 expand in the longitudinal direction of the deformation member 201, they can expand freely within the grooves 211. Therefore, the portion on the back side expands greatly with respect to the portion on the surface side, and as a result, it curves toward the surface side.

[0070] Note that the shape of the deformation member, the arrangement and shape of the grooves can be changed in the same manner as in the first embodiment. Also, it is preferable that the dimensions, arrangement, etc. of the grooves be the same values as in the first embodiment.

[0071] By making the cross-sectional shape of the groove hexagonal as in the deformation member 201 of this embodiment, the surface area inside the groove increases, so the swelling rate increases. Therefore, by changing the cross-sectional shape of the groove, it becomes possible to control the deformation speed.

[0072] Note that the shape of the groove formed in the deformation member is not limited to the shapes described in the first and second embodiments, and may be a semi-circular shape, a triangular shape, a polygonal shape, a star shape, or the like.

[0073] <Example> The following is an explanation of an experiment conducted to confirm that the deformable member is deformed so as to bend by wetting the deformable member. First, the inventors manufactured Examples 1 to 6 described below by the manufacturing method described above, and the side views of each example are shown in FIG. 7.

[0074] Example 1 As shown in FIG. 7(A), Example 1 was the deformable member 201 of the second embodiment. The dimensions of Example 1 are as follows. Length of deformable member: 50 mm Width of deformable member: 10 mm Thickness of deformable member: 4 mm Depth of groove: 2 mm Width of groove: 1.155 mm Interval between grooves: 4.016 mm

[0075] Example 2 As shown in FIG. 7(B), Example 2 was the deformable member 201 of the second embodiment. The dimensions of Example 2 are as follows. Length of deformable member: 50 mm Width of deformable member: 10 mm Thickness of deformable member: 4 mm Depth of groove: 3 mm Width of groove: 1.732 mm Interval between grooves: 3.246 mm

[0076] Example 3 As shown in FIG. 7(C), Example 3 was the deformable member 201 of the second embodiment. The dimensions of Example 3 are as follows. Length of deformable member: 50 mm Width of deformable member: 10 mm Thickness of deformable member: 4 mm Depth of groove: 1 mm Width of groove: 0.577 mm Interval between grooves: 4.786 mm

[0077] Example 4 As shown in Fig. 7(D), Example 4 used the deformation member 201 of the second embodiment. The dimensions of Example 4 are as follows. Length of the deformation member: 50 mm Width of the deformation member: 10 mm Thickness of the deformation member: 4 mm Depth of the groove: 2 mm Width of the groove: 1.15 mm Spacing between the grooves: 2.169 mm

[0078] Example 5 As shown in Fig. 7(E), Example 5 used the deformation member 201 of the second embodiment. The dimensions of Example 5 are as follows. Length of the deformation member: 50 mm Width of the deformation member: 10 mm Thickness of the deformation member: 4 mm Depth of the groove: 2 mm Width of the groove: 1.15 mm Spacing between the grooves: 10.479 mm

[0079] Example 6 As shown in Fig. 7(F), Example 6 used the deformation member 10 of the first embodiment. The dimensions of Example 1 are as follows. Length of the deformation member: 50 mm Width of the deformation member: 10 mm Thickness of the deformation member: 4 mm Depth of the groove: 2 mm Width of the groove: 2 mm Spacing between the grooves: 2.889 mm

[0080] For Examples 1 to 6, Acrylic acid (AA) was used as the polymer, N, N-methylene bis acrylamide (MBAA) was used as the crosslinking agent, diphenyl (2,4,6-trimethyl benzoyl)phosphine oxide (TPO) was used as the photoinitiator, and Sodium hydroxide (NaOH) was added and used. The Young's modulus of the materials of Examples 1 to 6 is 50 to 100 kPa.

[0081] When manufacturing Examples 1 to 6, 4M AA and 0.5 mol% MBAA were added to water and stirred for 5 minutes using a magnetic stirrer. Subsequently, 0.25 mol% TPO was added and stirring was continued for another 5 minutes. Finally, 3 mol% NaOH was gradually added to neutralize the solution. NaOH was added in four equal portions, and the solution was stirred until it was completely dissolved. After all the NaOH was added, the solution was covered with a glass plate and stirred for about 30 to 40 minutes. As a result, a transparent pre-gel solution was obtained. All measurement steps were performed inside a glove box under reduced pressure. Thereafter, the pre-gel solution was poured into a silicone mold and UV irradiation was performed for about 8 minutes. By this process, Examples 1 to 6 were formed.

[0082] The deformed members of Examples 1 to 6 were immersed in water and swollen. Figure 8 is a photograph showing the shapes of the deformed members of Examples 1 to 6 at 10 seconds, 20 seconds, 30 seconds, and 40 seconds after immersion in water. As shown in Figure 8, in all of Examples 1 to 6, the deformed members are curved in an arc shape such that the surface with the groove is on the inside. It can be said that the final bending angles are large for Examples 2 and 4, and the larger the groove depth (depth B) and the narrower the groove interval (interval C), the larger the bending angle.

[0083] That is, when it is desired to increase the bending angle of the deformed member, it is preferable to increase the groove depth (groove depth B / thickness F of the deformed member) and decrease the groove interval (increase the groove width A / groove interval C).

[0084] Also, Figure 9 is a graph showing the time change of the bending angles of Examples 1 to 6. As shown in Figure 9, Example 2 has a particularly high initial deformation rate, and Examples 1, 4, and 6 have a high deformation rate as a whole. Therefore, when it is desired to increase the deformation rate of the deformed member, it is preferable to increase the groove depth (groove depth B / thickness F of the deformed member), and it is also preferable to increase the groove width and decrease the groove interval (increase the groove width A / groove interval C).

[0085] <Application to Mask> Next, the application of the deformable member of the present embodiment will be described. FIG. 10 shows a mask for impregnating a cosmetic liquid using the deformable member of the present invention. The mask 500 for impregnating a cosmetic liquid includes a water-containing sheet 510 as a base material.

[0086] As the sheet 510, for example, a gel sheet can be used. As the gel constituting the gel sheet, a gel having a polymer as a hydrogel composition can be used, and the polymer includes one or more selected from the group consisting of polysaccharides (galactomannan, glucomannan, guar gum, locust bean gum, pluronic (registered trademark), agar, agar, algin, acacia gum, carrageenan, gellan gum, carrageenan, xanthan gum, cellulose, etc.), carbomer, polyacrylate, polyethylene, polyvinyl alcohol, polyvinylpyrrolidone, polyether, and polyester graft polyacrylate copolymer.

[0087] In addition to the polymer component, the gel may appropriately contain components usually used in cosmetics, such as surfactants, lower alcohols, oils, water, aqueous components, thickeners other than the polymer, powders, sequestering agents, cooling agents, antioxidants, antibacterial agents, colorants, various fragrances, etc., according to the purpose.

[0088] As surfactants, as anionic surfactants other than the above, salts of fatty acids such as lauric acid, myristic acid, palmitic acid, stearic acid, isostearic acid, sodium polyoxyethylene lauryl ether sulfate, ammonium polyoxyethylene lauryl ether sulfate, triethanolamine polyoxyethylene lauryl ether sulfate, etc.; alkyl sulfates such as sodium lauryl sulfate and triethanolamine lauryl sulfate; α-olefin sulfonates such as sodium tetradecene sulfonate and potassium tetradecene sulfonate; acyl isethionates such as sodium N-lauroyl isethionate and potassium N-lauroyl isethionate; N-acyl polypeptide salts such as sodium N-coconut oil fatty acid methyl taurate, sodium N-lauroyl methyl taurate, potassium N-coconut oil fatty acid methyl taurate, and sodium lauroyl hydrolyzed silk; and sulfosuccinic acids such as sodium sulfosuccinate. As amphoteric surfactants, as betaine acetate type surfactants, octyldimethylamino betaine, lauryldimethylamino betaine, coconut oil fatty acid amidopropyl betaine, coconut oil fatty acid alkyldimethylamino betaine, myristyldimethylamino betaine, cetyl dimethylamino betaine, coconut oil fatty acid amidopropyldimethylamino betaine, lauric acid amidopropyldimethylamino betaine, lauryldihydroxyethylamino betaine, cetyl dihydroxyethylamino betaine, etc. can be mentioned. Also, as imidazoline type surfactants, sodium N-coconut oil fatty acid acyl-N-carboxymethyl-N-hydroxyethyl ethylenediamine, disodium N-coconut oil fatty acid acyl-N-carboxymethoxyethyl-N-carboxymethyl ethylenediamine, etc. can be mentioned. Also, sodium lauryl aminodiacetate, etc. can also be mentioned.As cationic surfactants, amine salts such as alkylamine salts, polyamines, and amino alcohol fatty acid derivatives, alkyl quaternary ammonium salts, aromatic quaternary ammonium salts, pyridinium salts, imidazolium salts, etc., include stearyltrimethylammonium chloride, behenyltrimethylammonium chloride, cetyltrimethylammonium chloride, distearyldimethylammonium chloride, dibehenyldimethylammonium chloride, enka dicetyldimethylammonium chloride, stearyldimethylbenzylammonium chloride, dilauryl dimethylammonium chloride, dipolyoxyethylene (15 EO) coconut oil alkylmethylammonium chloride, dipolyoxyethylene (4 EO) lauryl ether dimethylammonium chloride, dicocoylethylhydroxyethylmonium sulfate, distearoylethylhydroxyethylmonium methosulfate, distearoylethylhydroxyethylmonium methosulfate, dipalmitoylethylhydroxyethylmonium methosulfate, palmitamidopropyltrimonium chloride, and phospholipids.Examples of nonionic surfactants include sorbitan fatty acid esters, glycerin fatty acid esters, polyglycerin fatty acid esters, propylene glycol fatty acid esters, polyethylene glycol fatty acid esters, sucrose fatty acid esters, polyoxyethylene alkyl ethers, polyoxypropylene alkyl ethers, polyoxyethylene alkyl phenyl ethers, polyoxyethylene fatty acid esters, polyoxyethylene sorbitan fatty acid esters, polyoxyethylene sorbitol fatty acid esters, polyoxyethylene glycerin fatty acid esters, polyoxyethylene propylene glycol fatty acid esters, polyoxyethylene castor oil, polyoxyethylene hydrogenated castor oil, polyoxyethylene phytostanol ether, polyoxyethylene phytosterol ether, polyoxyethylene cholestanol ether, polyoxyethylene cholesteryl ether, polyoxyalkylene-modified organopolysiloxane, polyoxyalkylene-alkyl copolymer-modified organopolysiloxane, lauric acid diethanolamide, coconut oil fatty acid diethanolamide, coconut oil fatty acid monoethanolamide, polyoxyethylene coconut oil fatty acid monoethanolamide, lauric acid monoisopropanolamide, coconut oil fatty acid monoisopropanolamide, polyoxypropylene coconut oil fatty acid monoisopropanolamide, alkanolamide, sugar ether, sugar amide, etc.

[0089] As the oil agent, oily components such as higher alcohols, hydrocarbon oils, ester oils, fats and oils, and silicone oils can be used. For example, higher alcohols such as lauryl alcohol, myristyl alcohol, palmityl alcohol, stearyl alcohol, behenyl alcohol, hexadecyl alcohol, oleyl alcohol, isostearyl alcohol, hexyl dodecanol, octyl dodecanol, cetostearyl alcohol, 2-decyltetradecynol, cholesterol, phytosterol, sitosterol, lanosterol, monostearyl glycerin ether (batyl alcohol), hydrocarbons such as ozokerite, squalane, squalene, ceresin, paraffin, paraffin wax, liquid paraffin, pristane, polyisobutylene, microcrystalline wax, petrolatum, ester oils such as diisobutyl adipate, 2-hexyldecyl adipate, di-2-heptylundecyl adipate, N-alkyl glycol monoisostearate, isocetyl isostearate, trimethylolpropane triisostearate, ethylene glycol di-2-ethylhexanoate, cetyl 2-ethylhexanoate, trimethylolpropane tri-2-ethylhexanoate, pentaerythritol tetra-2-ethylhexanoate, cetyl octanoate, octyldodecyl gum ester, oleyl oleate, octyldodecyl oleate, decyl oleate, neopentyl glycol dicaprate, triethyl citrate, 2-ethylhexyl succinate, isocetyl stearate, butyl stearate, diisopropyl sebacate, di-2-ethylhexyl sebacate, cetyl lactate, myristyl lactate, isopropyl palmitate, 2-ethylhexyl palmitate, 2-hexyldecyl palmitate, 2-heptylundecyl palmitate, cholesteryl 12-hydroxystearate, dipentaerythritol fatty acid ester, isopropyl myristate, octyldodecyl myristate, 2-hexyldecyl myristate, myristyl myristate, hexyl dodecyl dimethyloctanoate, ethyl laurate, hexyl laurate, diisostearyl malate, waxes such as beeswax, carnauba wax, candelilla wax, sperm whale oil, palm oil, palm kernel oil, olive oil, safflower oil,Vegetable oils represented by soybean oil, cottonseed oil, etc., animal oils such as beef tallow, beef foot tallow, beef bone tallow, hardened beef tallow, hardened oil, turtle oil, lard, horse fat, mink oil, liver oil, egg yolk oil, lanolin, liquid lanolin, reduced lanolin, lanolin alcohol, hard lanolin, lanolin acetate, lanolin fatty acid isopropyl and other lanolin derivatives, polyether-modified polysiloxane, polyoxyalkylene·alkylmethylpolysiloxane·methylpolysiloxane copolymer, alkoxy-modified polysiloxane, alkyl-modified polysiloxane, crosslinked organopolysiloxane, fluorine-modified polysiloxane, amino-modified polysiloxane, glycerin-modified polysiloxane, higher alkoxy-modified silicone, higher fatty acid-modified silicone, etc. may be mentioned.,

[0090] As the powder, any powder can be used as long as it is used in ordinary cosmetics, regardless of its shape (spherical, needle-like, plate-like, etc.), particle size (smoky, fine particles, pigment grade, etc.), and particle structure (porous, non-porous, etc.). For example, as inorganic powders, magnesium oxide, barium sulfate, calcium sulfate, magnesium sulfate, calcium carbonate, magnesium carbonate, talc, synthetic mica, mica, kaolin, sericite, muscovite, synthetic mica, phlogopite, biotite, lithia mica, silicic acid, anhydrous silicic acid, aluminum silicate, magnesium silicate, magnesium aluminum silicate, calcium silicate, barium silicate, strontium silicate, metal tungstate, hydroxyapatite, vermiculite, hydrillaite, montmorillonite, zeolite, ceramic powder, dicalcium phosphate, alumina, aluminum hydroxide, boron nitride, boron nitride, etc.; as organic powders, polyamide powder, polyester powder, polyethylene powder, polypropylene powder, polystyrene powder, polyurethane powder, benzoguanamine powder, polymethylbenzoguanamine powder, tetrafluoroethylene powder, polymethyl methacrylate powder, cellulose powder, silk powder, nylon powder, 12 nylon powder, 6 nylon powder, styrene-acrylic acid copolymer powder, divinylbenzene-styrene copolymer powder, vinyl resin powder, urea resin powder, phenol resin powder, fluororesin powder, silicone resin powder, acrylic resin powder, melamine resin powder, epoxy resin powder, polycarbonate resin powder, microcrystalline fiber powder, lauroyl lysine, silicone resin powder, etc.; as colored pigments, inorganic red pigments such as iron oxide, iron hydroxide, and iron titanate, inorganic brown pigments such as γ-iron oxide, inorganic yellow pigments such as yellow iron oxide and loess, inorganic black pigments such as black iron oxide and carbon black, inorganic purple pigments such as manganese violet and cobalt violet, inorganic green pigments such as chromium hydroxide, chromium oxide, cobalt oxide, and cobalt titanate, inorganic blue pigments such as ultramarine and ultramarine blue, lake pigments of tar-based pigments, lake pigments of natural pigments, and composite powders obtained by compounding these powders, etc.;Examples of pearl pigments include titanium oxide-coated mica, titanium oxide-coated mica, bismuth oxychloride, titanium oxide-coated bismuth oxychloride, titanium oxide-coated talc, fish scale foil, titanium oxide-coated colored mica, etc.; examples of metal powder pigments include aluminum powder, copper powder, stainless steel powder, etc.; examples of tar dyes include Red No. 3, Red No. 104, Red No. 106, Red No. 201, Red No. 202, Red No. 204, Red No. 205, Red No. 220, Red No. 226, Red No. 227, Red No. 228, Red No. 230, Red No. 401, Red No. 505, Yellow No. 4, Yellow No. 5, Yellow No. 202, Yellow No. 203, Yellow No. 204, Yellow No. 401, Blue No. 1, Blue No. 2, Blue No. 201, Blue No. 404, Green No. 3, Green No. 201, Green No. 204, Green No. 205, Orange No. 201, Orange No. 203, Orange No. 204, Orange No. 206, Orange No. 207, etc.; examples of natural pigments include powders selected from carminic acid, laccaic acid, carthamin, brazilein, crocin, etc., and powders obtained by compounding these powders or surface-treating them with an oil agent, silicone, or fluorine compound, etc.

[0091] The aqueous component may be any component soluble in water. For example, glycols such as propylene glycol, 1,3-butylene glycol, dipropylene glycol, and polyethylene glycol, glycerols such as glycerin, diglycerin, and polyglycerin, sugar alcohols such as sorbitol, maltitol, and glucose, lower alcohols such as ethanol, etc. may be mentioned. The water is not particularly limited, and examples include tap water, purified water, hot spring water, deep water, and plant extracts such as aloe vera, witch hazel, hamamelis, cucumber, lemon, lavender, and rose, and one kind or two or more kinds can be used. The content of the aqueous component in the present invention is not particularly limited, but is preferably 30 to 80% by mass. When it is within this range, the stability over time is better.

[0092] Examples of antibacterial agents include benzoic acid, sodium benzoate, salicylic acid, phenol, sorbic acid, potassium sorbate, parachlorometacresol, hexachlorophene, benzalkonium chloride, chlorhexidine chloride, trichlorocarbanilide, photosensitizer, zinc bis(2-pyridylthio-1-oxide), isopropylmethylphenol, etc. Examples of preservatives include paraoxybenzoic acid esters, phenoxyethanol, etc.

[0093] Note that the sheet 510 is not necessarily limited to a gel sheet, and a sheet made of a material such as a non-woven fabric can also be used.

[0094] Furthermore, on a part of the mask 500 for impregnating a lotion, a deformation member 520 is attached to the surface on the side that contacts the user's face. The deformation member 520 is formed in an elongated shape, and a plurality of grooves extending in the short side direction are formed at intervals in the long side direction. The deformation member is attached so that the surface on the side where the grooves are formed is located on the face side.

[0095] In the mask 500 of the present embodiment, as described below, the deformation member 520 is attached corresponding to the positions on the face where wrinkles are likely to occur. First, the deformation member 520 is provided to be inclined so that the interval expands downward symmetrically from the glabella to the side part of the bridge of the nose. Also, the deformation member 520 is provided to be inclined so that the interval expands upward symmetrically from the glabella to above the eyes. Also, the deformation member 520 is provided to be inclined upward from the outer corner of the eye toward the side. Two deformation members 520 are provided on each of the left and right outer corners of the eye. Also, the deformation member 520 is provided to expand downward along the left and right nasolabial folds.

[0096] The deformable member 520 is provided at portions on the surface of the face having unevenness and at portions where wrinkles are likely to occur where a lifting effect is expected. At a location corresponding to a portion where the surface of the face of the mask 500 is concave, it is preferable to provide the deformable member 520 such that a surface without a groove formed thereon faces the face side. At a location corresponding to a portion where the surface of the face of the mask 500 is convex, it is preferable to provide the deformable member 520 such that a surface with a groove formed thereon faces the face side. At a location corresponding to a portion where a lift-up of the mask 500 is expected, it is preferable to provide the deformable member 520 such that a surface with a groove formed thereon faces the face side.

[0097] The mask 500 is used by impregnating the mask 500 with a cosmetic liquid in a state where the mask 500 is attached to the face such that the surface on the side where the deformable member 520 is exposed contacts the face. Note that the mask 500 may be attached to the face after impregnating the mask 500 with the cosmetic liquid. As the cosmetic liquid to be impregnated, a liquid obtained by adding active ingredients such as pharmaceutical ingredients, moisturizing ingredients, and beauty ingredients to purified water, ethanol, etc. is used.

[0098] When the mask 500 is impregnated with the cosmetic liquid, the deformable member 520 gets wet together with the sheet 510 of the mask 500, and the deformable member 520 bends along the unevenness of the face. Thereby, the mask 500 fits to the face and the sheet 510 adheres closely. Further, portions where wrinkles are likely to occur such as nasolabial folds, crow's feet, and between the eyebrows are pulled, and a lifting effect is obtained.

[0099] In the present embodiment, a face mask that covers the entire face is described as an example of the mask. However, the present invention is not limited thereto, and the present invention can also be applied to a patch type that covers a part of the face such as crow's feet, and such a patch type is also included in the mask. Further, the mask is not limited to a face mask that covers the face, and also includes patches used to cover the décolletage and the like.

[0100] <Application to a stent> The deformable member of the present invention can also be used as a stent. FIG. 11 is a diagram for explaining an embodiment in which the deformable member of the present invention is used as a stent. As shown in FIG. 11, for example, when a part 320 of the blood vessel wall 310 protrudes inward, the stent 300 of this embodiment can be used to expand the protruding part 320 outward. The stent 300 is composed of the deformable members 10 and 201 described above.

[0101] For example, the stent 300 of this embodiment in a state before wetting is transported by a catheter to a location where the blood vessel wall 310 protrudes inward, the stent 300 is released into the blood vessel, and attached to the protruding part 320 facing inward. At this time, the stent 300 is attached such that the surface on the side where the groove of the deformable member is formed is located inside the blood vessel and the direction in which the groove extends is along the direction in which the blood vessel extends. Then, the stent 300 attached in this way swells due to the blood flowing through the blood vessel and deforms into an arc shape. As a result, the protruding part 320 facing inward is pushed and expanded by the stent 300.

[0102] Note that although the entire stent 300 of this embodiment is composed of a deformable member, it may be configured to include a deformable member in part.

[0103] <Application to Medicinal Capsules> The deformable member of the present invention can also be used as a medicinal capsule. FIG. 12 is a diagram showing a medicinal capsule using the deformable member according to the present invention. The medicinal capsule 400 according to this embodiment contains a drug 440 and is used, for example, to release the drug 440 at a desired organ in the body after oral ingestion of the medicinal capsule. As shown in FIG. 12, the medicinal capsule 400 has a bottom surface 410, a side wall 420, and a pair of upper lids 430. These bottom surface 410, side wall 420, and upper lids 430 are integrally formed of, for example, the same wettable gel material.

[0104] The bottom surface 410 is, for example, rectangular, and the side walls 420 are erected perpendicular to the bottom surface 410 along the periphery of the bottom surface 410. A pair of upper lids 430 extend from the upper edges of the opposing side walls 420 so as to face each other. These pair of upper lids 430 are each composed of the above-described deformation members 10, 201. Each upper lid has a groove formed on the outer surface side of the medicinal capsule 400. In the state before wetting, the inner edges of the upper lids 430 of the medicinal capsule 400 are in contact with each other.

[0105] According to such a medicinal capsule 400, when the medicinal capsule 400 reaches an organ such as the stomach, for example, and is wetted by gastric juice, the deformation members constituting the upper lid 430 curve outward. As a result, the medicinal capsule can be opened and the medicine 440 accommodated inside can be released.

Explanation of Signs

[0106] 10: Deformation member 11: Groove 12: Protrusion 100: Inverted type 110: Container part 120: Convex part 130: Concave part 140: Molding die 150: Container part 160: Convex part 170: Concave part 201: Deformation member 211: Groove 212: Protrusion 300: Stent 400: Medicinal capsule 410: Bottom surface 420: Side wall 430: Upper lid 440: Medicine 500: Mask 510: Sheet 520: Deformation member

Claims

1. A plate-shaped deformable member made of a swellable gel that swells by impregnation with a liquid, wherein a plurality of grooves extend in parallel on one surface.

2. The deformable member is made of a swellable gel having a constant cross-linking density in a single layer. The deformable member according to Claim 1.

3. The plurality of grooves extend in parallel. The deformable member according to Claim 1.

4. The groove has a polygonal cross-sectional shape. The deformable member according to Claim 1.

5. The groove has a rectangular or hexagonal cross-sectional shape that is symmetric about a vertical axis. The deformable member according to Claim 1.

6. The ratio (A / C) of the width A of the groove to the interval C between the grooves is 0.5 or more, and the ratio (B / F) of the depth B of the groove to the thickness F of the deformable member is 0.5 or more. The deformable member according to Claim 3.

7. The deformation speed per unit length of the deformable member is 0.06 degrees / sec·mm or more. The deformable member according to Claim 1.

8. The Young's modulus of the swellable gel is 50 to 100 kPa. The deformable member according to Claim 1.

9. The swellable gel includes a first polymer, a photoinitiator, a monomer that forms a second polymer by polymerization using the photoinitiator, and a light absorber, and the first polymer and the second polymer form a gel. The deformable member according to Claim 1.

10. A method for manufacturing a plate-shaped deformable member made of a swellable gel that swells by impregnation with a liquid, wherein a plurality of grooves are arranged in parallel on one surface of the deformable member, comprising the steps of: forming an inversion mold having a recess with an inversion of a molding die using a 3D printer; filling the inversion mold with an inversion mold material to form a molding die having a convex portion corresponding to the groove of the deformable member; filling the molding die with a material and cross-linking the material to form the deformable member. The method for manufacturing a deformable member.

11. The molding die includes silicone. The method for manufacturing a deformable member according to Claim 10.

12. A mask including at least a part of the deformable member according to any one of Claims 1 to 9.

13. A capsule including at least a part of the deformable member according to any one of Claims 1 to 9, accommodating a drug in an internal space, and opening the internal space to the outside when the deformable member deforms.

14. ​ A catheter including at least a part of the deformable member according to any one of claims 1 to 9, wherein the deformable member expands outward when it gets wet in a state of being disposed within a blood vessel.

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