Transfer equipment

Abstract

To provide transfer equipment capable of easily sticking a sheet-like material onto an inner wall of a luminal organ.SOLUTION: Transfer equipment includes: an outer cylinder for defining a through-hole penetrating in an axial direction; and an expansion shaft including a cylinder part for defining an insertion hole penetrating in the axial direction, which is inserted into the through-hole; and a moving shaft including a shank and a main carrier continued to a distal end of the shank on which a sheet-like material can be placed, which is inserted into the insertion hole. The expansion shaft includes an expansion arm supported swingably at the distal end of the cylinder part and a movable part for moving the distal end of the expansion arm in a radial direction of the outer cylinder.SELECTED DRAWING: Figure 1

Description

[Technical Field]

[0001] The present disclosure relates to a transfer device. [Background technology]

[0002] BACKGROUND ART A transfer device for transferring a sheet-like material such as a cell sheet to a treatment target site in a living body is known. Patent Document 1 discloses this type of transfer device.

[0003] The transfer device disclosed in Patent Document 1 includes a first carrier member including a first shaft and a first support member provided at the tip of the first shaft and having a first support surface, and a second carrier member including a moving member including a second shaft extending along the axial direction of the first shaft and a second support member provided at the tip of the moving member and having a second support surface smaller than the first support surface. In the transfer device disclosed in Patent Document 1, the first support surface supports an overhanging portion of the medical sheet that overhangs outward from the second support surface when the second support member is positioned above the first support surface, and the second carrier member is movable relative to the first carrier member from a first position where the entire second support surface is positioned above the first support surface to a second position where the second support surface is positioned distal to the tip of the first support member. [Prior art documents] [Patent documents]

[0004] [Patent Document 1] International Publication No. 2023 / 234380 Summary of the Invention [Problem to be solved by the invention]

[0005] According to the transfer device of Patent Document 1, by moving the second carrier member from the first position to the second position, the second support part is moved from above the first support part onto the target area of ​​the living body, placing the protruding part of the medical sheet on the target area, and then pulling out the second support part from between the medical sheet and the target area, the entire medical sheet can be brought into contact with the target area. This allows the medical sheet to be transferred efficiently to the target area.

[0006] However, when using a transfer device such as that described in Patent Document 1 to attach a sheet-like material to the inner wall of a hollow organ such as the large intestine, it may be difficult to attach the sheet-like material if the inner wall of the hollow organ is in a relaxed state.

[0007] An object of the present disclosure is to provide a transfer device that can easily attach a sheet-like material to the inner wall of a hollow organ. [Means for solving the problem]

[0008] A transfer device according to a first aspect of the present disclosure includes: (1) an outer cylinder defining a through hole that penetrates in the axial direction; an expansion shaft having a cylindrical portion that defines an insertion hole that penetrates in the axial direction and is inserted into the through hole; a moving shaft that is inserted through the insertion hole and includes a shaft portion and a main carrier that is connected to a distal end of the shaft portion and on which a sheet-like object can be placed; The expansion shaft an extension arm swingably supported at the distal end of the cylindrical portion; a movable part that moves the distal end of the expansion arm in the radial direction of the outer tube.

[0009] In one embodiment of the present disclosure, a transfer device comprises: (2) the movable portion includes a slider and a connecting portion that connects the slider and the expansion arm and is supported so as to be swingable relative to the slider and the expansion arm, The movable part is a transfer device as described in (1) above, in which the slider moves in the axial direction relative to the tubular part, thereby swinging the extension arm via the connecting part and moving the distal end of the extension arm in the radial direction.

[0010] In one embodiment of the present disclosure, a transfer device comprises: (3) The transfer device according to (2) above, wherein the outer cylinder is provided with a stopper portion that restricts the movement of the slider toward the distal side.

[0011] In one embodiment of the present disclosure, a transfer device comprises: (4) The transfer device according to any one of (1) to (3) above, wherein the extension arm defines a suction channel having a suction port that opens at the distal end of the extension arm.

[0012] In one embodiment of the present disclosure, a transfer device comprises: (5) The transfer device according to (4) above includes a connecting tube that defines a connecting flow path that connects the suction flow path and a pressure reduction flow path defined in the peripheral wall of the cylindrical portion.

[0013] In one embodiment of the present disclosure, a transfer device comprises: (6) In the transferring device according to any one of (1) to (5) above, a plurality of the expansion arms are provided at different positions in the circumferential direction of the outer cylinder.

[0014] In one embodiment of the present disclosure, a transfer device comprises: (7) the expansion shaft includes a support carrier connected to a distal end of the tubular portion; The support carrier is a transfer device described in any one of (1) to (6) above, which is capable of placing an overhanging portion of the sheet-like object that is not placed on the main carrier when the sheet-like object is placed on the main carrier.

[0015] In one embodiment of the present disclosure, a transfer device comprises: (8) The main carrier is the transferring device according to any one of (1) to (6) above, on which the entire sheet-like material can be placed. [Effects of the Invention]

[0016] According to the present disclosure, a transfer device can be provided that can easily attach a sheet-like material to the inner wall of a hollow organ. [Brief explanation of the drawings]

[0017] [Figure 1] 1 illustrates a transfer device according to one embodiment of the present disclosure. [Figure 2A] FIG. 2 shows details of the carrier deployment configuration of the delivery device of FIG. 1. [Figure 2B] 2B is a cross-sectional view of the transfer device at the position of line II in FIG. 2A. [Figure 3A] FIG. 2 shows details of the delivery configuration of the delivery device of FIG. 1. [Figure 3B] 3B is a cross-sectional view of the transfer device taken along line II-II of FIG. 3A. [Figure 4A] FIG. 2 shows details of the suction mechanism of the transfer device of FIG. 1. [Figure 4B] 4B is a cross-sectional view of the transfer device taken along line III-III of FIG. 4A. [Figure 5A] FIG. 10 illustrates the delivery device being inserted into the large intestine in the delivery configuration. [Figure 5B] 5B shows the state of FIG. 5A, with the delivery device in the carrier deployment configuration. [Figure 5C] FIG. 5C is a diagram showing a state in which the main carrier has been moved distally relative to the support carrier from the state shown in FIG. 5B, and the sheet-like material has been placed at the treatment target site. [Figure 5D] 10 is a diagram showing a state in which the main carrier is moved closer to the sheet-like material and then pulled out from the sheet-like material. FIG. [Figure 6A]FIG. 10 illustrates details of a carrier deployment configuration of a delivery device according to one embodiment of the present disclosure. [Figure 6B] 6B is a cross-sectional view of the transfer device taken along line IV-IV of FIG. 6A. [Figure 7A] FIG. 6B shows details of the delivery configuration of the delivery device of FIG. 6A. [Figure 7B] 7B is a cross-sectional view of the transfer device taken along line VV in FIG. 7A. DETAILED DESCRIPTION OF THE INVENTION

[0018] DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Hereinafter, an embodiment of a transfer device according to the present disclosure will be described by way of example with reference to the drawings, in which the same components are designated by the same reference numerals.

[0019] First Embodiment FIG. 1 is a diagram showing a transfer device 1 as one embodiment of a transfer device according to the present disclosure. The transfer device 1 is a medical device for transferring a sheet-like material 80 to a treatment target site on the inner wall of a hollow organ. As will be described in detail below, the transfer device 1 is used, for example, to treat damage to the inner wall W of the large intestine 90. In this case, the sheet-like material 80 is transferred by the transfer device 1 to the treatment target site on the inner wall W of the large intestine 90. The sheet-like material 80 is then separated from the transfer device 1 and released, and attached to the treatment target site. In this way, the sheet-like material 80 is used to treat the treatment target site.

[0020] The sheet-like material 80 is not particularly limited as long as it is a sheet-like material used for treating a treatment target site. The sheet-like material 80 may be, for example, tissue made of a biological material; a cell culture; or a material made of various materials such as plastic, paper, woven fabric, nonwoven fabric, metal, polymer, or lipid. When the sheet-like material 80 is a cell sheet containing cells, the cells contained in the cell sheet include, for example, somatic stem cells (adult stem cells), or differentiated cells derived from ES cells (embryonic stem cells) or iPS cells (induced pluripotent stem cells). Somatic stem cells include, for example, mesenchymal stem cells, vascular endothelial cells (endothelial stem / progenitor cells), and skeletal myoblasts (myoblast cells). Differentiated cells include, for example, cardiomyocytes and fibroblast cells. In addition, cells may include, for example, cell lines, genetically-modified cells.

[0021] As described above, the sheet-like material 80 may be any type of sheet-like substance and is not particularly limited. However, with the transfer device 1, even a fragile sheet-like material 80 that is easily deformed or damaged, such as a cell sheet, can be easily transferred to the treatment target site and released toward the treatment target site. Therefore, the transfer device 1 is particularly useful when used to transfer a fragile sheet-like material 80 that is easily deformed or damaged, such as a cell sheet.

[0022] When a cell sheet is used as the sheet-like material 80, the thickness of the cell sheet may be, for example, about 100 μm. The diameter of the cell sheet may be, for example, about 60 mm. However, the thickness and diameter (size) of the cell sheet can be set as appropriate.

[0023] The sheet-like material 80 may also be a cell sheet to be transplanted into a hollow organ other than the large intestine 90, such as the small intestine or esophagus. The sheet-like material 80 may also be, for example, a plastic sheet used to prevent adhesion of organs.

[0024] As shown in FIG. 1, delivery device 1 comprises an outer tube 10, an extension shaft 20, and a moving shaft 50. FIG. 2A is a diagram showing details of the delivery device 1 of FIG. 1 in the carrier deployment configuration. FIG. 2B is a cross-sectional view of delivery device 1 taken along line II in FIG. 2A. Note that FIG. 2B does not show the shaft 31 of extension arm 30. FIG. 3A is a diagram showing details of the delivery configuration of delivery device 1 of FIG. 1. FIG. 3B is a cross-sectional view of delivery device 1 taken along line II-II in FIG. 3A.

[0025] [Outer cylinder 10] The outer cylinder 10 is a cylindrical member that defines a through hole 10a therein. Hereinafter, the direction parallel to the central axis O of the outer cylinder 10 will be referred to as the "axial direction A of the outer cylinder 10" or simply as the "axial direction A." Furthermore, the direction around the central axis O of the outer cylinder 10 will be referred to as the "circumferential direction B of the outer cylinder 10" or simply as the "circumferential direction B." Furthermore, the radial direction of a circle around the central axis O of the outer cylinder 10 will be referred to as the "radial direction C of the outer cylinder 10" or simply as the "radial direction C." The through hole 10a of the outer cylinder 10 penetrates in the axial direction A. The outer shape of the cross section of the outer cylinder 10 perpendicular to the axial direction A is not particularly limited. The outer shape of the cross section of the outer cylinder 10 perpendicular to the axial direction A may be, for example, a circular shape or an oval shape such as an ellipse.

[0026] The outer cylinder 10 is made of a flexible material. The material of the outer cylinder 10 is not particularly limited, but examples thereof include polyethylene, polypropylene, fluororesin, polyethylene terephthalate, polymethyl methacrylate, polyamide resin, polystyrene, polycarbonate, polyimide, polyetherimide, polyether ether ketone, polyvinyl chloride, ABS resin, etc. The outer cylinder 10 may also be made of a metal material.

[0027] [Extended shaft 20] The extension shaft 20 is inserted into the through-hole 10a of the outer cylinder 10. The extension shaft 20 of this embodiment includes a cylindrical portion 21, a support carrier 25, an extension arm 30, a movable portion 35, and a suction mechanism 40.

[0028] (Cylinder part 21) The tubular portion 21 is a cylindrical member extending along the axial direction A. The tubular portion 21 defines an insertion hole 21a that penetrates in the axial direction A. The length of the tubular portion 21 in the axial direction A of the present embodiment is longer than the length of the outer tube 10 in the axial direction A. The tubular portion 21 in the present embodiment includes a proximal protrusion 22 that protrudes from the proximal end of the outer tube 10. Furthermore, the outer shape of a cross section of the tubular portion 21 that is perpendicular to the axial direction A is not particularly limited. The outer shape of the cross section of the tubular portion 21 that is perpendicular to the axial direction A may be, for example, a circular shape or an oval shape such as an ellipse.

[0029] The cylindrical portion 21 is made of a flexible material, similar to the outer cylinder 10. The material of the cylindrical portion 21 is not particularly limited, and examples thereof include the various resin materials exemplified above as the material of the outer cylinder 10. The cylindrical portion 21 may also be made of a metal material.

[0030] (Support Carrier 25) The support carrier 25 is connected to the distal end of the tubular portion 21. As will be described in detail later, when the sheet-like material 80 is placed on the main carrier 55, the support carrier 25 can place an overhanging portion 80a (see FIG. 2B) of the sheet-like material 80 that is not placed on the main carrier 55.

[0031] The support carrier 25 of this embodiment is a flexible sheet member. The support carrier 25 may be made of, for example, a resin material. The constituent material of the support carrier 25 is not particularly limited, but examples thereof include polycarbonate, polyamide, polystyrene, polypropylene, polyacetal resin, polyimide, polyether ether ketone, polyethylene terephthalate, and fluororesin. Furthermore, the support carrier 25 preferably has transparency in the thickness direction. The thickness of the support carrier 25 is not particularly limited, but is preferably, for example, 100 μm or more and 200 μm or less.

[0032] The support carrier 25 and the cylindrical portion 21 may be connected to each other by, for example, an adhesive. The adhesive is not particularly limited, but examples thereof include UV adhesives and instant adhesives (e.g., cyanoacrylate instant adhesives). The support carrier 25 and the cylindrical portion 21 may also be connected to each other by, for example, heat fusion of the support carrier 25 to the cylindrical portion 21.

[0033] (extension arm 30) The expansion arm 30 of this embodiment includes an expansion shaft portion 31 and a suction portion 32 connected to the distal end of the expansion shaft portion 31.

[0034] The expansion shaft 31 of this embodiment is a rod-shaped member that extends linearly. The proximal end of the expansion shaft 31 of this embodiment is supported to be swingable relative to the distal end of the tubular portion 21. The expansion shaft 31 of this embodiment is supported to be swingable relative to the tubular portion 21 at the distal end thereof via a support shaft 23 provided at the distal end of the tubular portion 21. The constituent material of the expansion shaft 31 is not particularly limited, and examples thereof include the various resin materials exemplified as constituent materials of the outer tube 10 described above. The expansion shaft 31 may also be made of a metal material.

[0035] The suction section 32 is connected to the distal end of the expansion shaft section 31 and forms the distal end of the expansion arm 30. A suction port 32a is defined in the suction section 32. The suction section 32 can adhere to the inner wall of a hollow organ by performing suction through the suction port 32a. This will be described in detail later. The suction section 32 is preferably made of a flexible material. Examples of materials that can be used to make the suction section 32 include the various resin materials exemplified above as materials for making the outer tube 10. The suction section 32 may also be made of a metal material.

[0036] As shown in FIG. 3B , three extension arms 30 are provided at different positions in the circumferential direction B of the outer tube 10. However, the number of extension arms 30 is not particularly limited and may be, for example, one, two, or four or more. When there are two extension arms 30, the extension arms 30 may be arranged so that their distal ends (the suction section 32 in this embodiment) are spaced apart from each other in the carrier-deployed form of the delivery device 1, which will be described later. When there are three extension arms 30, as in this embodiment, the extension arms 30 may be arranged so that their distal ends (the suction section 32 in this embodiment) are located at the vertices of a right triangle or an isosceles triangle when viewed from the axial direction A in the carrier-deployed form of the delivery device 1, which will be described later. When there are four extension arms 30, the extension arms 30 may be arranged so that their distal ends (the suction section 32 in this embodiment) are located at the vertices of a square or a rhombus when viewed from the axial direction A in the carrier-deployed form of the delivery device 1, which will be described later.

[0037] (Movable part 35) The movable portion 35 includes a slider 36 and a connecting portion 37. The slider 36 is supported by the cylindrical portion 21 so as to be movable in the axial direction A relative to the cylindrical portion 21. More specifically, the slider 36 of this embodiment is a cylindrical member that defines a hollow portion that penetrates in the axial direction A. The slider 36 of this embodiment has an inner circumferential surface 36a (see FIGS. 2A and 3A) that defines this hollow portion, which is fitted into the outer circumferential surface 21c of the cylindrical portion 21. The inner circumferential surface 36a (see FIGS. 2A and 3A) of the slider 36 is slidable in the axial direction A relative to the outer circumferential surface 21c of the cylindrical portion 21.

[0038] The connecting part 37 connects the slider 36 and the extension arm 30. In this embodiment, the connecting part 37 is a rod-shaped member that extends linearly so as to straddle the slider 36 and the extension arm 30. The connecting part 37 is supported so as to be swingable relative to both the slider 36 and the extension arm 30. More specifically, the proximal end of the connecting part 37 is supported at the distal end of the slider 36 via a first shaft member 38a (see FIGS. 2A and 3A) that is inserted into the mounting hole of the slider 36 so as to be swingable relative to the slider 36. Furthermore, the distal end of the connecting part 37 is supported at the middle of the extension arm 30 via a second shaft member 38b (see FIGS. 2A and 3A) that is inserted into the mounting hole of the extension shaft part 31 of the extension arm 30 so as to be swingable relative to the extension arm 30.

[0039] By having such a slider 36 and connecting portion 37, the movable portion 35 can swing the extension arm 30 via the connecting portion 37 by moving the slider 36 in the axial direction A relative to the tubular portion 21, and move the distal end of the extension arm 30 in the radial direction C.

[0040] The material of the movable part 35 is not particularly limited, but examples thereof include the various resin materials exemplified above as the material of the outer cylinder 10. The movable part 35 may also be made of a metal material.

[0041] (Suction mechanism 40) The suction mechanism 40 is a mechanism for adsorbing the suction part 32, which is the distal end of the extension arm 30, to the inner wall of a hollow organ. FIG. 4A is a diagram showing details of the suction mechanism 40 of this embodiment. FIG. 4B is a cross-sectional view of the transfer instrument 1 at the position of line III-III in FIG. 4A. As shown in FIG. 4A, the suction mechanism 40 of this embodiment includes a tubular part 21, an extension arm 30, and a connecting tube 41.

[0042] As shown in Figures 4A and 4B, the tubular portion 21 of this embodiment defines a pressure reduction channel 21b in its peripheral wall. The pressure reduction channel 21b of this embodiment extends along the axial direction A. The expansion arm 30 of this embodiment also defines a suction channel 30a therein. The suction channel 30a of this embodiment extends along the length of the expansion shaft portion 31 of the expansion arm 30. The suction channel 30a of this embodiment includes a suction port 32a that opens into the suction portion 32, which serves as the distal end of the expansion arm 30. A connecting tube 41 connects the tubular portion 21 and the expansion arm 30. More specifically, the proximal end of the connecting tube 41 of this embodiment is connected to the tubular portion 21, and the distal end is connected to the expansion shaft portion 31 of the expansion arm 30. The connecting tube 41 of this embodiment defines a connecting channel 41a that connects the suction channel 30a and the pressure reduction channel 21b when the expansion shaft portion 31 and the tubular portion 21 of the expansion arm 30 are connected. That is, the suction flow path 30a and the decompression flow path 21b are connected via the connecting flow path 41a. Therefore, in the suction mechanism 40 of this embodiment, the suction flow path 30a can be decompressed via the connecting flow path 41a by decompressing the decompression flow path 21b using an external device such as a decompression pump connected to the transfer instrument 1. As a result, suction is performed from the suction port 32a, and the suction unit 32, which is the distal end of the expansion arm 30, can be adsorbed onto the inner wall of a hollow organ.

[0043] The connecting tube 41 of this embodiment is a flexible tubular member. The constituent material of the connecting tube 41 is not particularly limited, but examples thereof include the various resin materials exemplified as constituent materials of the outer tube 10 described above. The connecting tube 41 may also be made of a metal material. [Moving shaft 50] The moving shaft 50 is inserted through the insertion hole 21a of the cylindrical portion 21. The moving shaft 50 includes a shaft portion 51 and a main carrier 55 connected to the distal end of the shaft portion 51.

[0044] (shaft 51) The shaft portion 51 extends along the axial direction A. The length of the shaft portion 51 in the axial direction A in this embodiment is longer than the lengths of the outer tube 10 and the tubular portion 21 in the axial direction A. The shaft portion 51 in this embodiment has a proximal protrusion 52 that protrudes from the proximal end of the tubular portion 21. The outer shape of the cross section of the shaft portion 51 perpendicular to the axial direction A is not particularly limited. The outer shape of the cross section of the shaft portion 51 perpendicular to the axial direction A may be, for example, a circular shape or an oval shape such as an ellipse.

[0045] The shaft portion 51 is made of a flexible material, similar to the above-described outer tube 10 and tube portion 21. The material of the shaft portion 51 is not particularly limited, and examples thereof include the various resin materials exemplified as the material of the above-described outer tube 10. The shaft portion 51 may also be made of a metal material.

[0046] (Main carrier 55) The main carrier 55 is connected to the distal end of the shaft portion 51 and forms the distal end of the moving shaft 50. The main carrier 55 of this embodiment is a flexible sheet member, similar to the support carrier 25 described above. The constituent material of the main carrier 55 is not particularly limited, but examples thereof include the various resin materials exemplified as constituent materials of the support carrier 25 described above. Furthermore, it is preferable that the support carrier 25 is transparent in the thickness direction. The thickness of the support carrier 25 is not particularly limited, but is preferably, for example, 100 μm or more and 200 μm or less.

[0047] The connection between the main carrier 55 and the shaft portion 51 may be, for example, by adhesive. The adhesive is not particularly limited, but examples thereof include UV adhesive and instant adhesive (e.g., cyanoacrylate instant adhesive). The connection between the main carrier 55 and the shaft portion 51 may also be, for example, by heat fusion of the main carrier 55 to the shaft portion 51.

[0048] 2A and 2B show the carrier-deployed form of the transfer device 1, in which the main carrier 55 and support carrier 25 of the transfer device 1 are in an unfolded state. As shown in FIGS. 2A and 2B, in the carrier-deployed form of the transfer device 1, the main carrier 55 protrudes from the distal end of the outer tube 10 and the cylindrical portion 21 of the extension shaft 20, and is in an unfolded state on which a sheet-like object 80 can be placed. Also, as shown in FIGS. 2A and 2B, in the carrier-deployed form of the transfer device 1, the support carrier 25 protrudes from the distal end of the outer tube 10, and is in an unfolded state on which, with the sheet-like object 80 placed on the main carrier 55, the protruding portion 80a of the sheet-like object 80 that is not placed on the main carrier 55 can be placed.

[0049] 2A and 2B, the extension arm 30 protrudes from the distal end of the outer tube 10. At this time, as shown in FIG. 2A, the extension arm 30 is swung by the movable part 35, and the distal end of the extension arm 30 is moved outward in the radial direction C from the inner circumferential surface 10b of the outer tube 10.

[0050] 3A and 3B show the transfer form of the transfer instrument 1, which is the form in which the transfer instrument 1 is transferred to the vicinity of a treatment target site in a hollow organ. In the transfer form of the transfer instrument 1, the main carrier 55 is rolled up into a cylindrical shape from the unfolded state shown in FIGS. 2A and 2B and is housed within the outer tube 10. In addition, in the transfer form of the transfer instrument 1, the support carrier 25 is rolled up into a cylindrical shape from the unfolded state shown in FIGS. 2A and 2B and is housed within the outer tube 10. Note that the extension arm 30 of this embodiment does not come into contact with the main carrier 55 and the support carrier 25 when housed within the outer tube 10 (transfer form of the transfer instrument 1).

[0051] 3A and 3B, the extension arm 30 is swung by the movable part 35 from the state shown in FIG. 2A, and the distal end of the extension arm 30 is moved inward in the radial direction C from the inner circumferential surface 10b of the outer tube 10. In this state, the extension arm 30, together with the main carrier 55 and the support carrier 25, is housed within the outer tube 10.

[0052] Furthermore, the transfer device 1 of this embodiment includes an operating portion 60 and a stopper portion 65 .

[0053] [Operation unit 60] The operating unit 60 includes a first handle portion 61, a second handle portion 62, and a third handle portion 63.

[0054] The first handle portion 61 of this embodiment is provided at the proximal end of the outer tube 10. The first handle portion 61 of this embodiment is slightly larger than the outer tube 10 in the radial direction C. The first handle portion 61 of this embodiment defines a recess 61a into which the proximal end of the outer tube 10 is fitted and fixed, and a retaining hole 61b that is connected to the proximal side of this recess 61a and through which the tubular portion 21 of the extension shaft 20 is inserted. The outer peripheral surface 21c of the tubular portion 21 is fitted into the inner peripheral surface of the first handle portion 61 that defines the retaining hole 61b. This prevents the tubular portion 21 from shifting in the radial direction C relative to the outer tube 10. Furthermore, when the first handle portion 61 is moved in the axial direction A, the extension shaft 20 can be moved together with the outer tube 10 in the axial direction A due to frictional resistance (static friction force) acting between the outer peripheral surface 21c of the tubular portion 21 and the inner peripheral surface of the first handle portion 61 that defines the retaining hole 61b. On the other hand, by sliding the outer surface 21c of the tubular portion 21 in the axial direction A against the inner surface of the first handle portion 61 that defines the retaining hole 61b, the extension shaft 20 can be moved in the axial direction A relative to the outer tube 10.

[0055] The second handle portion 62 of this embodiment is provided at the proximal end of the tubular portion 21 of the expansion shaft 20. The second handle portion 62 of this embodiment is slightly larger in the radial direction C than the tubular portion 21 of the expansion shaft 20. The second handle portion 62 of this embodiment defines a recess 62a into which the proximal end of the tubular portion 21 of the expansion shaft 20 is fitted and fixed, and a retaining hole 62b that is connected to the proximal side of this recess 62a and through which the shaft portion 51 of the movable shaft 50 is inserted. The outer peripheral surface 51a of the shaft portion 51 of this embodiment is fitted into the inner peripheral surface of the second handle portion 62 that defines the retaining hole 62b. This makes it possible to prevent the shaft portion 51 from shifting in the radial direction C relative to the tubular portion 21. Furthermore, when the second handle portion 62 is moved in the axial direction A, the frictional resistance (static friction force) acting between the outer peripheral surface 51a of the shaft portion 51 and the inner peripheral surface of the second handle portion 62 that defines the retaining hole 62b causes the movable shaft 50 to move in the axial direction A together with the extension shaft 20. On the other hand, by sliding the outer peripheral surface 51a of the shaft portion 51 in the axial direction A against the inner peripheral surface of the second handle portion 62 that defines the retaining hole 62b, the movable shaft 50 can be moved in the axial direction A relative to the extension shaft 20.

[0056] The third handle portion 63 of this embodiment is provided at the proximal end of the shaft portion 51 of the moving shaft 50. The third handle portion 63 of this embodiment is one size larger in the radial direction C than the shaft portion 51 of the moving shaft 50.

[0057] A user such as a doctor can move the extension shaft 20 and the movable shaft 50 in the axial direction A relative to the outer tube 10 by gripping the first handle portion 61 to fix the position of the outer tube 10 and moving the second handle portion 62 in the axial direction A. A user such as a doctor can also move the movable shaft 50 in the axial direction A relative to the outer tube 10 and the extension shaft 20 by gripping the second handle portion 62 to fix the positions of the outer tube 10 and the extension shaft 20 and moving the third handle portion 63 in the axial direction A.

[0058] The constituent material of the operating portion 60 is not particularly limited, but examples thereof include the various resin materials exemplified above as constituent materials of the outer cylinder 10. The operating portion 60 may also be made of a rubber material or a metal material.

[0059] [Stopper part 65] The stopper portion 65 of this embodiment is provided on the outer tube 10 and restricts the movement of the slider 36 toward the distal side. The stopper portion 65 of this embodiment is a protrusion that protrudes inward in the radial direction C from the inner circumferential surface 10b of the outer tube 10 in a part of the circumferential direction B. Three stopper portions 65 of this embodiment are provided at different positions in the circumferential direction B. However, the configuration of the stopper portions 65 is not particularly limited as long as it is possible to restrict the movement of the slider 36 toward the distal side. For example, the stopper portion 65 may be configured to protrude inward in the radial direction C from the inner circumferential surface 10b of the outer tube 10 over the entire area of ​​the circumferential direction B.

[0060] The constituent material of the stopper portion 65 is not particularly limited, but examples thereof include the various resin materials exemplified above as constituent materials of the outer cylinder 10. The stopper portion 65 may also be made of a rubber material or a metal material.

[0061] (How to use) Next, an example of how to use the transfer device 1 will be described. First, as shown in FIG. 2A , the transfer device 1 is placed in the carrier-deployed state. Specifically, the support carrier 25 of the extension shaft 20 and the main carrier 55 of the moving shaft 50 are protruded from the distal end of the outer tube 10, and the support carrier 25 and the main carrier 55 are placed in the deployed state. In this embodiment, the deployed state of the support carrier 25 and the main carrier 55 refers to the state of the support carrier 25 and the main carrier 55 shown in FIGS. 2A and 2B . In this state, the sheet-like object 80 is placed on the main carrier 55 and the support carrier 25. More specifically, in this embodiment, the sheet-like object 80 is placed on the main carrier 55, and the protruding portion 80a of the sheet-like object 80 protruding from the main carrier 55 is placed on the support carrier 25.

[0062] Next, as shown in FIGS. 3A and 3B, the transfer instrument 1 is put into the transfer configuration. When changing the configuration of the transfer instrument 1 from the carrier deployment configuration (see FIGS. 2A and 2B) to the transfer configuration (see FIGS. 3A and 3B), the first handle portion 61 is grasped to fix the position of the outer tube 10, while the second handle portion 62 is moved proximally. This moves the expansion shaft 20 and the moving shaft 50 proximally relative to the outer tube 10, and the main carrier 55, the support carrier 25, and the sheet-like material 80 placed on the main carrier 55 and the support carrier 25 are pulled into the outer tube 10. At this time, the main carrier 55 and the support carrier 25 abut against the distal end of the outer tube 10, and are rolled into a cylindrical shape together with the sheet-like material 80 placed thereon, and are pulled into the outer tube 10. In this transfer configuration, the transfer instrument 1 is inserted into the vicinity of the treatment target site of the luminal organ. In addition, in the carrier-deployed form of the transfer instrument 1, the expansion arm 30 of this embodiment is located on the upper surface side of the support carrier 25 (the surface side on which the sheet-like material 80 is placed) with respect to the support carrier 25. In addition, in the transfer form of the transfer instrument 1, the expansion arm 30 of this embodiment is housed inside the support carrier 25, which has been rolled into a cylindrical shape, as shown in Fig. 3B. Below, with reference to Figs. 5A to 5D, an example will be described in which the transfer instrument 1 is inserted into the large intestine 90, which is a tubular organ, in the transfer form and used.

[0063] Fig. 5A is a diagram showing a state in which the transfer instrument 1 is inserted into the large intestine 90 in the transfer form. Fig. 5B is a diagram showing a state in which the transfer instrument 1 is in the carrier deployed form from the state of Fig. 5A. Fig. 5C is a diagram showing a state in which the main carrier 55 has been moved distally relative to the support carrier 25 from the state of Fig. 5B, and the sheet-like material 80 has been placed at the treatment target site. Fig. 5D is a diagram showing a state in which the main carrier 55 has been moved proximally relative to the sheet-like material 80, and the main carrier 55 has been pulled out from the sheet-like material 80.

[0064] As shown in FIG. 5A, when delivery device 1 is inserted into large intestine 90 in the delivery configuration, the inner wall W of large intestine 90 is in a relaxed state.

[0065] Next, as shown in FIG. 5B, the transfer instrument 1 is returned to the carrier-deployed configuration. Specifically, with the distal end of the outer tube 10 positioned near the treatment target site on the inner wall W of the large intestine 90, the first handle portion 61 is grasped to fix the position of the outer tube 10, while the second handle portion 62 is moved distally. This moves the expansion shaft 20 and the movable shaft 50 distally, causing the main carrier 55 and the support carrier 25 to protrude from the distal end of the outer tube 10. At this time, the main carrier 55 and the support carrier 25 are in the deployed state, returning to the state shown in FIG. 2A. In other words, with the distal end of the outer tube 10 positioned near the treatment target site on the inner wall W of the large intestine 90, the transfer instrument 1 is transformed from the transfer configuration to the carrier-deployed configuration.

[0066] When the delivery device 1 is returned to the carrier deployment form, as the tubular portion 21 moves distally, the slider 36 of the movable portion 35 also moves distally. However, while the slider 36 is moving the tubular portion 21 distally, its distal movement is restricted by a stopper portion 65 provided on the outer tube 10. After the distal movement of the slider 36 is restricted by the stopper portion 65, the tubular portion 21 moves distally relative to the slider 36. As a result, the expansion arms 30 are swung via the connecting portions 37 of the movable portion 35, and the distal ends of the expansion arms 30 move outward in the radial direction C. As a result, as shown in FIG. 5B , a portion of the inner wall W of the large intestine 90 is pushed open by the distal ends of the expansion arms 30, resulting in an expanded state.

[0067] Furthermore, when a portion of the inner wall W of the large intestine 90 is pushed open by the distal end of the expansion arm 30, suction is performed in advance from the suction port 32a in the suction unit 32 serving as the distal end of the expansion arm 30. Specifically, before the transfer instrument 1 is put into the carrier expanded form, an external device such as a vacuum pump connected to the transfer instrument 1 is driven. This reduces the pressure in the vacuum flow path 21b of the tubular portion 21, the connecting flow path 41a of the connecting tube 41, and the suction flow path 30a of the expansion arm 30, and suction is performed from the suction port 32a. By performing suction from the suction port 32a in advance in this way, the suction unit 32 can be adsorbed to the inner wall W of the large intestine 90 when a portion of the inner wall W of the large intestine 90 is pushed open by the suction unit 32.

[0068] Next, as shown in FIG. 5C , the main carrier 55 is moved distally relative to the support carrier 25, and the sheet-like material 80 placed on the main carrier 55 is placed at the treatment target site. Specifically, while the second handle portion 62 is gripped to fix the positions of the outer tube 10 and the extension shaft 20, the third handle portion 63 is moved distally. This moves the main carrier 55 distally relative to the support carrier 25, and the sheet-like material 80 placed on the main carrier 55 can be placed at the treatment target site. At this time, the protruding portion 80a (see FIG. 2B ) of the sheet-like material 80 that protrudes from the main carrier 55 is placed at the treatment target site. By placing (contacting) the protruding portion 80a of the sheet-like material 80 on (with) the treatment target site in this manner, it is possible to prevent the sheet-like material 80 from moving together with the main carrier 55 when the main carrier 55 is later pulled away from the sheet-like material 80.

[0069] Next, as shown in Fig. 5D, the main carrier 55 is pulled out from the sheet-like material 80. Specifically, while the second handle portion 62 is grasped to fix the positions of the outer tube 10 and the extension shaft 20, the third handle portion 63 is moved proximally. This moves the main carrier 55 proximally relative to the sheet-like material 80, and the main carrier 55 is pulled out from the sheet-like material 80. By the above operation, the sheet-like material 80 can be attached to the treatment target area.

[0070] [Action and effect] As described above, the expansion shaft 20 of the transfer device 1 of this embodiment comprises the expansion arm 30 that is swingably supported on the distal end of the tubular portion 21, and the movable portion 35 that moves the distal end of the expansion arm 30 in the radial direction C of the outer tube 10. According to the above configuration, by using the movable portion 35 to move the distal end of the expansion arm 30 outward in the radial direction C, the distal end of the expansion arm 30 can expand the inner wall of a hollow organ such as the large intestine 90. Then, by attaching the sheet-like material 80 to the inner wall of the hollow organ in a state where the inner wall of the hollow organ is expanded, the sheet-like material 80 can be easily attached to the inner wall of the hollow organ.

[0071] The movable section 35 of this embodiment comprises a slider 36 and a connecting section 37 that connects the slider 36 and the expansion arm 30 and is supported so as to be swingable relative to the slider 36 and the expansion arm 30. Furthermore, the slider 36 of this embodiment moves in the axial direction A relative to the tubular section 21, thereby swinging the expansion arm 30 via the connecting section 37 and moving the distal end of the expansion arm 30 in the radial direction C. With the above configuration, it is possible to easily realize a movable section 35 that moves the distal end of the expansion arm 30 in the radial direction C of the outer tube 10.

[0072] The outer tube 10 of this embodiment is provided with a stopper portion 65 that restricts the distal movement of the slider 36. According to the above configuration, it becomes easy to move the tube portion 21 distally relative to the slider 36.

[0073] The expansion arm 30 of this embodiment defines a suction flow path 30a having a suction port 32a that opens at the distal end of the expansion arm 30. According to the above configuration, by performing suction through the suction port 32a, the distal end of the expansion arm 30 (the suction unit 32 in this embodiment) can be adsorbed to the inner wall of the hollow organ. This prevents slippage between the inner wall of the hollow organ and the distal end of the expansion arm 30 (the suction unit 32 in this embodiment), ensuring expansion of the inner wall of the hollow organ by the distal end of the expansion arm 30 (the suction unit 32 in this embodiment).

[0074] The transfer device 1 of this embodiment includes a connecting tube 41 that defines a connecting flow path 41a that connects the suction flow path 30a to the pressure reduction flow path 21b defined in the peripheral wall of the tubular portion 21. With the above configuration, the pressure in the suction flow path 30a can be reduced via the pressure reduction flow path 21b and the connecting flow path 41a. This allows for easy suction from the suction port 32a.

[0075] In this embodiment, multiple expansion arms 30 (three in this embodiment) are provided at different positions in the circumferential direction B of the outer tube 10. With the above configuration, the distal end of the expansion arm 30 can more reliably expand the inner wall of the hollow organ compared to when only one expansion arm 30 is provided. Furthermore, in the carrier-deployed form of the transfer device 1, the expansion arm 30 in this embodiment is arranged so that its distal end (the suction section 32 in this embodiment) is located at the vertex of a right triangle or an isosceles triangle when viewed from the axial direction A. With the above configuration, a triangular three-dimensional space can be formed inside the hollow organ by expanding the inner wall of the hollow organ with the expansion arm 30. Furthermore, by positioning the main carrier 55 at the flat base of this triangular space, the main carrier 55 can be easily advanced distally.

[0076] The expansion shaft 20 of this embodiment includes a support carrier 25 connected to the distal end of the tubular portion 21. The support carrier 25 of this embodiment is capable of placing the protruding portion 80a of the sheet-like material 80 that is not supported by the main carrier 55 when the sheet-like material 80 is placed on the main carrier 55. With the above configuration, it is possible to prevent wrinkles from occurring in the protruding portion 80a of the sheet-like material 80 before the sheet-like material 80 is transferred to the treatment target site of the tubular organ.

[0077] Second Embodiment Next, referring to Figures 6A to 7B, a description will be given of a transfer device 101 as another embodiment of a transfer device according to the present disclosure. Transfer device 101 of this embodiment differs from the above-described transfer device 1 mainly in the configuration of the main carrier and the presence or absence of a support carrier, but the other configurations are the same. Here, the above-described differences will be mainly described, and a description of the configurations common to transfer device 1 will be omitted.

[0078] Fig. 6A is a diagram showing details of the carrier deployment configuration of delivery device 101. Fig. 6B is a cross-sectional view of the delivery device taken along line IV-IV in Fig. 6A. Note that Fig. 6B does not show the shaft 31 of extension arm 30. Fig. 7A is a diagram showing details of the delivery configuration of delivery device 101. Fig. 7B is a cross-sectional view of the delivery device taken along line VV in Fig. 7A.

[0079] As shown in Figures 6A and 6B, the expansion shaft 120 of this embodiment does not include a support carrier. More specifically, in the above-described delivery device 1, a support carrier 25 is connected to the distal end of the tubular portion 21 of the expansion shaft 20, whereas in this embodiment, a support carrier is not connected to the distal end of the tubular portion 21. Therefore, in the carrier-expanded form of the delivery device 101 of this embodiment (see Figures 6A and 6B), only the main carrier 155 protrudes from the outer tube 10 and the distal end of the tubular portion 21 of the expansion shaft 120, and the delivery device 101 is in an expanded state in which a sheet-like material 80 can be placed thereon.

[0080] 6A and 6B, the main carrier 155 of the moving shaft 150 of this embodiment is capable of carrying the entire sheet-like material 80. This makes it possible to prevent wrinkles from forming in the sheet-like material 80 before it is transferred to the treatment target site of the hollow organ, even if the expansion shaft 120 does not include a support carrier.

[0081] Next, an example of how to use the transfer device 101 will be described. First, as shown in FIG. 6A, the transfer device 101 is put into the carrier deployed state. Specifically, the main carrier 155 of the moving shaft 150 is protruded from the distal end of the outer tube 10, and the main carrier 155 is put into the deployed state. In this embodiment, the deployed state of the main carrier 155 refers to the state of the main carrier 155 shown in FIGS. 6A and 6B. In this state, the entire sheet-like material 80 is placed on the main carrier 155.

[0082] 7A and 7B, the transfer instrument 101 is put into the transfer configuration. This operation is the same as that of the transfer instrument 1 described above, so a detailed description will be omitted. In this transfer configuration, the transfer instrument 101 is inserted to the vicinity of the treatment target site of the hollow organ.

[0083] Next, with the delivery device 101 inserted into the hollow organ, as shown in Figures 6A and 6B, the delivery device 101 is again put into the carrier deployment form. This operation is similar to that of the delivery device 1 described above, so a detailed explanation will be omitted. As a result, the inner wall of the hollow organ is pushed open by the distal ends of the expansion arms 30, and the hollow organ is put into an expanded state. Note that, as shown in Figure 7B, the delivery device 1 of this embodiment is provided with two expansion arms 30. Therefore, in this embodiment, the inner wall of the hollow organ is pushed open into an oval shape by the two expansion arms 30.

[0084] Next, the sheet-like material 80 is placed opposite the treatment target area on the inner wall of the hollow organ. Specifically, the moving shaft 150 is operated to adjust the position of the main carrier 155 so that the sheet-like material 80 faces the treatment target area. Next, the moving shaft 150 is operated to press the sheet-like material 80 placed on the main carrier 155 against the treatment target area on the inner wall of the hollow organ. Finally, the moving shaft 150 is operated to move the main carrier 155 away from the sheet-like material 80. By the above operations, the sheet-like material 80 can be attached to the treatment target area on the inner wall of the hollow organ.

[0085] In this way, the above-described transferring device 1 and the transferring device 101 of this embodiment can be used differently depending on the method of attaching the sheet-like material 80 to the inner wall of the hollow organ.

[0086] The transfer device according to the present disclosure is not limited to the specific configurations shown in the above-described embodiments, and various modifications, changes, and combinations are possible without departing from the scope of the claims. [Industrial Applicability]

[0087] The present disclosure relates to a transfer device. [Explanation of symbols]

[0088] 1, 101: Transfer equipment 10: Outer cylinder 10a: Through hole 20, 120: Extension shaft 21:Cylinder part 21a: Insertion hole 21b: Pressure reduction channel 21c: Outer surface of the cylindrical part 22: Proximal protrusion of the tube 23: Support shaft part 25: Support Carrier 30: Extended Arm 30a: Suction channel 31: Extended shaft 32: Suction part 32a: Suction port 35: Moving part 36: Slider 36a: Inner surface of slider 37:Connection part 38a: First shaft member 38b: 2nd shaft member 40:Suction mechanism 41: Connecting tube 41a: connecting flow path 50, 150: Moving shaft 51: Shaft 52: Proximal protrusion of shaft 55, 155: Main carrier 60:Operation unit 61: First handle part 61a: Recessed portion of first handle portion 61b: Retaining hole of first handle part 62: Second handle part 62a: Recessed portion of second handle 62b: Retaining hole of second handle part 65: Stopper part 80: Sheet-like member 90: Large intestine A: Axial direction of the outer cylinder B: Circumferential direction of the outer cylinder C: Radial direction of outer cylinder O: Center axis of the outer cylinder W: Inner wall of the large intestine

Claims

1. an outer cylinder defining a through hole that penetrates in the axial direction; an expansion shaft having a cylindrical portion that defines an insertion hole that penetrates in the axial direction and is inserted into the through hole; a moving shaft that is inserted through the insertion hole and includes a shaft portion and a main carrier that is connected to a distal end of the shaft portion and on which a sheet-like object can be placed; The expansion shaft an extension arm swingably supported at the distal end of the cylindrical portion; a movable portion that moves the distal end of the extension arm in a radial direction of the outer cylinder.

2. the movable portion includes a slider and a connecting portion that connects the slider and the expansion arm and is supported so as to be swingable relative to the slider and the expansion arm, The delivery device of claim 1 , wherein the movable portion swings the extension arm via the connecting portion when the slider moves in the axial direction relative to the cylindrical portion, thereby moving the distal end of the extension arm in the radial direction.

3. 3. The transfer device of claim 2, wherein the outer cylinder is provided with a stopper portion that restricts distal movement of the slider.

4. 4. A transfer device according to any one of claims 1 to 3, wherein the extension arm defines a suction channel having a suction port opening at a distal end of the extension arm.

5. The transfer device according to claim 4 , further comprising a connecting tube defining a connecting flow path connecting the suction flow path and a pressure reduction flow path defined in the peripheral wall of the cylindrical portion.

6. The transfer device according to any one of claims 1 to 3, wherein a plurality of the expansion arms are provided at different positions around the circumference of the outer cylinder.

7. the expansion shaft includes a support carrier connected to a distal end of the tubular portion; A transfer device according to any one of claims 1 to 3, wherein the support carrier is capable of supporting a protruding portion of the sheet-like object that is not placed on the main carrier when the sheet-like object is placed on the main carrier.

8. 4. The transfer device according to claim 1, wherein the main carrier is capable of placing the entire sheet-like object thereon.

Images