Triglyceride detergent

Abstract

To provide a detergent having excellent detergency against triglyceride.SOLUTION: A detergent against triglyceride for scalp and / or hair use comprises at least one selected from the group consisting of polyoxyethylene fatty acid glyceryl and / or alkyl glucoside. Also, a detergent for scalp and / or hair use comprises polyoxyethylene (capryl / capric acid) glyceryl, and (b) at least one selected from the group consisting of taurine, Coptis japonica extract, Phellodendron amurense extract, and Rubus suavissimus extract.SELECTED DRAWING: None

Description

[Technical Field]

[0001] The present invention relates to a detergent having excellent detergency against triglycerides. [Background technology]

[0002] Human scalp sebum is made up of triglycerides, free fatty acids, squalene, wax esters, etc. It is composed of approximately 40% of triglycerides, which are the main components. It has been reported (Non-Patent Document 1). Sebum covers the surface of the skin and prevents the intrusion of foreign substances from the outside. It plays a physiological role in preventing excess secretion of skin oils and preventing water leakage from the body. Oil can cause various scalp problems (bad odor, dandruff, stickiness, inflammation, etc.). In recent years, with the increasing trend of people becoming more conscious of cleanliness, hair cleansers (such as shampoos) with excellent sebum-cleansing properties have become increasingly popular. Daily care is required.

[0003] Surfactants are essential ingredients for hair cleansers to have a cleansing effect on sebum stains. Examples of the cleaning mechanisms of surfactants include rolling up, emulsification, and solubilization. Solubilization is involved in the cleaning mechanism of hair cleansing agents such as shampoo, and other mechanisms are involved. Therefore, in order to effectively remove sebum stains, To achieve this, it is necessary to add a sufficient amount of surfactant to solubilize the sebum components. However, excessive use of surfactants can wash away the intercellular lipids that are responsible for the skin's natural barrier function, leading to poor health. From the above perspective, even a small amount can be used to sufficiently remove sebum stains. It has excellent cleaning power against sebum stains (especially triglycerides, which are its main component) so that It is necessary to select a cleaning agent that is suitable for the purpose, but such research has not yet been sufficient. [Prior art documents] [Non-patent literature]

[0004] [Non-Patent Document 1] Oil Chemistry Vol.37(No.10),827-831,1988 [Non-patent document 2] Introduction to Hair Care Science, 1st Edition, Fragrance Journal, 2011 Summary of the Invention [Problem to be solved by the invention]

[0005] The present invention provides a cleaning agent that has excellent detergency against triglycerides, which are the main components of sebum stains. The present invention aims to provide a drug. [Means for solving the problem]

[0006] The present inventors have investigated the solubilization of various components in triolein, a type of triglyceride. A screening evaluation of triglyceride detergents was carried out by measuring the limiting concentration. As a result, polyoxyethylene fatty acid glyceryl and alkyl glucoside have outstanding properties. It was found that it has cleaning power against triglycerides. By combining Caprylic / Capric Glyceryl with certain ingredients or extracts, The present invention was completed based on the discovery that the cleaning power of

[0007] That is, the present invention provides: (1) Polyoxyethylene fatty acid glyceryl and / or alkyl glucoside, Cleansing agents for triglycerides, characterized in that they are for skin and / or hair, (2) The cleaning agent according to (1), wherein the triglyceride is triolein. (3) Polyoxyethylene fatty acid glyceride is polyoxyethylene coconut oil fatty acid glyceride or polyoxyethylene (caprylic / capric acid) glyceryl (1) or (2) The cleaning agent according to (4) Any of (1) to (3) in which the alkyl glucoside is alkyl (8-16) glucoside A cleaning agent according to any one of the preceding claims. (5) (a) polyoxyethylene (caprylic / capric acid) glyceryl, and (b) tau a small amount selected from the group consisting of phosphorus, coptis extract, Phellodendron bark extract, and Tencha extract a cleansing agent for scalp and / or hair, which contains at least one of the above-mentioned compounds; is. [Effects of the Invention]

[0008] The present invention provides a detergent having excellent detergency against triglycerides. It has become possible. DETAILED DESCRIPTION OF THE INVENTION

[0009] The triglyceride detergent of the present invention contains polyoxyethylene fatty acid glyceryl and / or acetylated glyceryl. It contains alkyl glucoside and is used for the scalp and / or hair. The cleaning agent of the present invention contains polyoxyethylene (caprylic / capric acid) glyceryl, and , taurine, Coptis Rhizome extract, Phellodendron Bark extract, and Tencha extract. The composition contains at least one of the above and is used for the scalp and / or hair. The above ingredients should be of the same quality as those normally used in pharmaceuticals, quasi-drugs, or cosmetics. It is possible.

[0010] Polyoxyethylene fatty acid glyceryl is a safe, non-ionic surfactant with excellent emulsifying and dispersing properties. It is an anionic surfactant and can be used for a variety of purposes in the cosmetic field. Specific examples of oxyethylene fatty acid glyceryl include polyoxyethylene coconut oil fatty acid glyceryl. Lyceryl, Polyoxyethylene (Caprylic / Capric Acid) Glyceryl, Polyoxyethylene Glyceryl Caprylate, Polyoxyethylene Glyceryl Laurate, Polyoxyethylene Examples include glyceryl monooleate, polyoxyethylene monococonut oil fatty acid glyceryl, etc. It can be used in a variety of applications, including polyoxyethylene coconut oil fatty acid glyceryl, polyoxyethylene (caprylic / capric triglyceride), It is more preferable to use glyceryl / caprate. Two or more of them may be used in combination as appropriate.

[0011] The content of polyoxyethylene fatty acid glyceryl is sufficient to provide the desired effect. Although there is no particular limitation, the amount of the surfactant in the cleaning agent of the present invention is preferably 0.01 to 20% by mass, more preferably The content is preferably 0.1 to 10% by mass.

[0012] Alkyl glucosides are non-ionic surfactants derived from natural ingredients, in which sugars and higher alcohols are glycosidicly bonded. It is a carboxylic surfactant and is known as a cleaning ingredient with excellent foaming properties and safety. Specific examples of alkyl glucosides include alkyl (8-16) glucosides. It is more preferable to use one having an alkyl group having 8 to 10 carbon atoms. These may be used alone or in combination of two or more. .

[0013] The content of alkyl glucoside is not particularly limited as long as the desired effect is sufficiently imparted. However, in the cleaning agent of the present invention, the amount is preferably 0.01 to 20 mass %, more preferably 0.1 It is about 10% by mass.

[0014] Taurine (also known as aminoethylsulfonic acid, 2-aminoethanesulfonic acid) is Cas No. 107 -35-7, and can be synthesized by general chemical synthesis or by fish and shellfish, especially mollusks (octopus). It can be extracted from various reagent and raw material manufacturers. It is also possible to use products purchased from

[0015] The content of taurine is not particularly limited as long as the desired effect is sufficiently imparted, but In the detergent of the present invention, the amount is preferably 0.001 to 10 mass %, more preferably 0.01 to 5 mass %. % by volume.

[0016] Coptis japonica Makino extract is extracted from the rhizomes of Coptis japonica Makino or other plants of the same genus. The extract is obtained from Phellodendron amurense (scientific name: Phellodendron amurense Rup. It is an extract obtained from the bark of the tree (Tencha spp.) or other plants of the same genus after removing the periderm. The extract is obtained from the leaves of the plant Rubus suavissimus, which belongs to the Rosaceae family. The extraction method for the above extract is not particularly limited, and can be carried out according to a conventional method. The extraction solvent used in the above step can be either a polar solvent or a non-polar solvent. For example, water, ethanol, propylene glycol, 1,3-butylene glycol, and the like. The above extract may be used as the extracted solution, or may be used in a liquid mixture as needed. Depending on the requirements, the product may be concentrated, diluted, filtered, decolorized with activated carbon, deodorized, or precipitated with ethanol. Furthermore, the extracted solution may be subjected to processes such as concentration to dryness, spray drying, freeze drying, etc. Alternatively, commercially available products may be used.

[0017] The content of the Coptis Rhizome extract, Phellodendron Bark extract or Tencha extract is adjusted to a level that satisfies the desired effect. There is no particular limitation as long as it is added, but in the detergent of the present invention, it is preferable to add 0.0001 The content is preferably from 0.001 to 5% by mass, and more preferably from 0.001 to 3% by mass.

[0018] In addition to the above-mentioned components, the detergent of the present invention may contain other conventional ingredients within the range that does not impair the effects of the present invention. Various ingredients used in cosmetics, quasi-drugs, pharmaceuticals, etc. can be added. For example, Anionic surfactants (N-acylmethylalanine salts, N-acylglutamate salts, N- Amino acid salts such as acylaspartates and N-acyltaurates, α-olefin sulfonates, Sulfonates, fatty acid salts, sulfosuccinates, alkyl ether carboxylates, acyl lactates , alkyl sulfates, alkyl ether sulfates, polyoxyethylene alkyl ether sulfates Salt, polyoxyethylene alkyl ether acetate, higher fatty acid alkanolamide sulfate etc.), amphoteric surfactants (alkyl betaine type, alkyl amide betaine type, amide sulfonate Betaine type, amino acid type, imidazoline type, amine oxide type, etc.), nonionic surfactants Detergents (polyoxyethylene alkyl ether, polyoxypropylene alkyl ether, Polyethylene glycol fatty acid ester, polyethylene glycol fatty acid diester, Glycerin ester, polyoxyethylene polyoxypropylene alkyl ether, fatty acid Alkanolamide, glycerin fatty acid ester, polyglycerin fatty acid ester, sucrose Sugar fatty acid ester, propylene glycol fatty acid ester, sorbitan fatty acid ester, Polyoxyethylene sorbitan mono fatty acid ester, polyoxyethylene sorbitan fat Acid ester, polyoxyethylene sorbitan fatty acid ester, polyoxyethylene hardened hydroxybenzoate Mashi oil, etc.), cationic polymers (cationized cellulose, cationic guar gum, cationic Polychlorinated xanthan gum, polychlorinated dimethylmethylene piperidinium, dimethyldiallyl chloride Ammonium-acrylamide copolymer, acrylamide-acrylic acid-dimethyl chloride Allyl ammonium copolymer, etc.), excipients, fragrances, freshening agents (menthol, peppermint oil, influenza, etc.), anti-inflammatory agents (guaiazulene, salicylic acid, glycyrrhizinate, glycyrrhetinic acid, acid, etc.), disinfectants (chlorhexidine gluconate, isopropyl methylphenol, Quaternary ammonium salts, piroctone olamine, etc.), preservatives (parabens (methylparaben, Ethylparaben, butylparaben, propylparaben, etc.), benzoic acid or its salts, aldehyde Sodium acetate, phenoxyethanol, hinokitiol, etc., moisturizers (hyaluronic acid or or its salts, chondroitin sulfate, etc.), extracts of various animals and plants, vitamins (retinol acetate , ascorbic acid, thiamine nitrate, cyanocobalamin, biotin, riboflavin, etc.), Oxidizing agents (dibutylhydroxytoluene, sodium pyrosulfite, tocopherol, edetate) sodium carbonate, ascorbic acid, isopropyl gallate, etc.), solubilizers (various vegetable oils, Various animal oils, alkyl glyceryl ethers, hydrocarbons, etc.), metabolic activators, gelling agents (water Water-soluble polymers, adhesives, etc. can be blended as appropriate depending on the purpose.

[0019] The cleaning agent of the present invention can be used for cosmetics, quasi-drugs, pharmaceuticals, etc. The cleanser is preferably used as a shampoo or scalp cleanser. [Example]

[0020] The present invention will be explained in more detail below with reference to examples, comparative examples and test examples. The present invention is not limited in any way by these examples. Represents "mass %."

[0021] (Test Example 1) The solubility limit concentration of various components is measured for triolein, a type of triglyceride. The cleaning power was evaluated by this test.

[0022] Purified water, triolein, and the various components listed in Table 1 were added at a final concentration of 1%. The solution was weighed to a concentration of 0.1 to 0.001%, and 10 g of mixed aqueous solutions of various concentrations were prepared. The mixture was shaken at room temperature for 1 hour, then left to stand overnight at room temperature. The surface activity of each sample was measured using a UV-visible spectrophotometer (UV-2450, Shimadzu Corporation). The absorbance at 600 nm of the aqueous solution of the activator / triolein mixture was measured as turbidity. The turbidity value is plotted against the concentration of ethanol, and the point where the turbidity begins to increase rapidly (inflection point) is determined. The triolein concentration obtained was calculated as the triolein solubilization limit concentration.

[0023] (Test results) Those with a triolein solubilization limit concentration of 0.001% or more were considered to have excellent cleaning power (○). The results of the evaluation are shown in Table 1. .

[0024] [Table 1]

[0025] Examples 1 to 3 are made of polyoxyethylene fatty acid glyceryl or alkyl glucoside. It has a high triolein solubilization limit concentration and excellent cleaning power against triolein. On the other hand, in Comparative Examples 1 to 16 in which other ingredients were used, the triolein solubilization limit was It was found that the concentration was low and the cleaning power against triolein was insufficient.

[0026] (Test Example 2) By measuring the solubilization limit concentration when various ingredients are combined, we can evaluate the effect of improving cleaning power. went.

[0027] Purified water, triolein, polyoxyethylene (caprylic / capric acid) glyceryl and The various components listed in Table 2 were added at the final concentrations listed in Table 2, and the final triolein concentration was 0.07 to 0.0 The mixture was weighed out so that the concentration was 0.1%, and 10 g of mixed aqueous solutions of various concentrations were prepared. The mixture was shaken and then left to stand overnight at room temperature. After mixing by inversion, the mixture was left to stand for at least one more hour (to degas). , polyoxyethylene (capsules) was measured using an ultraviolet-visible spectrophotometer (UV-2450, Shimadzu Corporation). The absorbance at 600 nm of a mixed aqueous solution of glyceryl (glyceryl / caprate) / triolein was measured as a turbidity index. The turbidity values ​​were plotted against the triolein concentration, and the turbidity increased rapidly. The triolein concentration at the point where the inflection point begins is calculated as the triolein solubilization limit concentration. did.

[0028] (Test results) Compared with Example 2, the improvement rate of the triolein solubilization limit concentration was 10% or more. Combinations with excellent detergency improvement effect (○), those with an improvement rate of 0 to less than 10% were considered to have improved detergency. Combinations with insufficient effect (△), and combinations with negative improvement rates are those with no effect on improving cleaning power. The evaluation results are shown in Table 2.

[0029] [Table 2]

[0030] In Examples 4 to 7, the triolein solubilization limit concentration was dramatically improved compared to Example 2, and the washing On the other hand, the comparative example in which other ingredients were combined Combinations 17 to 20 do not improve the triolein solubilization limit concentration and are insufficient in improving cleaning power. Therefore, it was found that polyoxyethylene (capryl / capric Glyceryl acetate, taurine, coptis extract, Phellodendron bark extract, and Tencha extract It has been revealed that the combination of ingredients selected from the above ingredients is an excellent cleanser for the scalp or hair. It became like this. [Industrial Applicability]

[0031] This invention provides excellent cleansing power against triglycerides, the main component of sebum stains on the scalp. It has become possible to provide a cleaning agent having the above properties.

Claims

1. Polyoxyethylene fatty acid glyceryl and / or alkyl glucoside A triglyceride containing at least one of the compounds of the present invention, which is for scalp and / or hair. Cleansing agent for lycerides.

2. 2. The cleaning agent of claim 1, wherein the triglyceride is triolein.

3. The polyoxyethylene fatty acid glyceryl is polyoxyethylene coconut oil fatty acid glyceryl 3. The composition according to claim 1 or 2, wherein the compound is polyoxyethylene caprylic / capric acid glyceryl. Detergent listed.

4. 4. The method according to claim 1, wherein the alkyl glucoside is an alkyl (8-16) glucoside. The cleaning agent according to any one of claims 1 to 4.

5. (a) polyoxyethylene (caprylic / capric acid) glyceryl, and (b) taurine , Coptis japonica extract, Phellodendron bark extract, and Zhenjiang tea extract A cleansing agent characterized by containing one of the above and being for scalp and / or hair.

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