Hydrogen-containing inhalable pharmaceutical composition for preventing, ameliorating, or treating cognitive dysfunction

An inhalable hydrogen composition suppresses oxidative stress and inflammation, inducing nerve growth factors to treat cognitive impairment, using a system for consistent hydrogen delivery.

JP2025169420APending Publication Date: 2025-11-12GOOTZ CO LTD
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Patent Information

Application Number
JP2025139933
Authority / Receiving Office
JP · JP
Patent Type
Applications
Current Assignee / Owner
Priority Date
2023-07-25
Filing Date
2025-08-25
Publication Date
2025-11-12

AI Technical Summary

Technical Problem

The effectiveness of hydrogen gas in preventing, improving, or treating cognitive impairment is unknown, and there is a need for a system that can supply patients with a constant hydrogen concentration for medical use.

Method used

An inhalable pharmaceutical composition containing 1% to 5% hydrogen gas, which can suppress the production of nitric oxide and reactive oxygen species, and induce the production of nerve growth factors, is administered via a system that includes a hydrogen gas generation module, chamber, flow control units, and a gas mixer to maintain a constant hydrogen-air mixture.

Benefits of technology

The composition effectively prevents, improves, or treats cognitive impairment by reducing oxidative stress and inflammation in nerve cells, inducing nerve growth factors, and stabilizes the hydrogen-air mixture for consistent administration.

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Abstract

To provide an inhalable pharmaceutical composition for treating cognitive dysfunction.SOLUTION: A system for producing an inhalable pharmaceutical composition for treatment which contains hydrogen and is capable of treating cognitive dysfunction by inhibiting the production of nitric oxide and the accumulation of reactive oxygen species due to oxidative stress in nerve cells comprises: a control module 600; a hydrogen gas production module 100 which produces hydrogen gas by electrodialysis of water; a hydrogen chamber 200 which stores hydrogen gas supplied from the hydrogen gas production module; a hydrogen flow adjustment unit 300 which adjusts the flow of the hydrogen gass discharged from the hydrogen chamber; an accumulator 400 which stores air supplied from the outside; an air flow adjustment unit 500 which adjusts the flow of the air discharged from the accumulator; and a gas mixing unit 700 which is provided so as to make the hydrogen gas and the air discharged from the hydrogen chamber and the accumulator flow therein and mixes the flowed-in hydrogen gas and the flowed-in air.SELECTED DRAWING: Figure 1
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Citation Information

Patent Citations

  • hydrogen-oxygen mixing gas generator and system for generating hydrogen-oxygen mixing gas using the same

    KR101344047B1