Electron pencil beam-based magnetic adjustment electron ray treatment apparatus and system

Abstract

To enable irradiation even when electron ray irradiation is required for a site located outside a linear irradiation range of an electron ray.SOLUTION: The present invention relates to an electron pencil beam-based magnetic adjustment electron ray treatment apparatus. The apparatus comprises: an electron ray output part for outputting an electron ray; a catheter part receiving application of the electron ray, which is output from the electron ray output part, and passing the electron ray through a hollow tunnel of a catheter; a magnetic field generation part for generating a magnetic field for refracting the electron ray passing through the hollow tunnel of the catheter; and a joint driving part having one side connected to the electron ray output part and the other side connected to a power source part, and enabling the electron ray output part, the catheter, and the magnetic field generation part to move with respect to the power source part. The catheter part adjusts movement and a rotational angle of the catheter in response to control by a control part, and can adjust a distribution of the electron ray irradiated to a treatment target while moving the magnetic field generation part together with the catheter in response to control by the control part.SELECTED DRAWING: Figure 3

Description

[Technical Field]

[0001] The present invention relates to an electron beam therapy device and system, particularly to a deep subcutaneous and spherical electron beam therapy device and system in a patient's body. The direction and dose of the electron beam can be adjusted to cover areas outside the linear irradiation range of the electron beam, such as curved surfaces. It is possible to irradiate electron beams while minimizing electron beam losses and reducing power consumption. This invention relates to a sagittal pencil beam based magnetically modulated electron beam therapy device and system. [Background technology]

[0002] In recent years, with the advent of an aging society, the standard of living of the people has improved, and the need to live a healthy life has become more important. Therefore, there is a tendency for interest in early diagnosis and treatment of diseases to gradually increase.

[0003] In particular, a radiotherapy device is a medical device that uses radiation to treat illnesses, and can be used for X-rays, electrons, etc. The use of radiation such as neutrons and protons to slow or destroy the growth of malignant tumor tissue such as cancer. It is a destructive treatment device.

[0004] However, when normal tissues in the human body are exposed to excessive amounts of high-energy radiation, This can cause the death of important tissue cells, or lead to genetic defects or even cancer.

[0005] When normal tissue and tumor tissue are close to each other, the side effects of radiation can make it difficult to administer sufficient radiation therapy doses. A malfunction occurs where the light cannot be emitted for a certain period of time.

[0006] Therefore, it is important to ensure that the tumor to be destroyed during radiation therapy receives sufficient radiation and that the tumor is removed. It must be adjusted to minimize damage to surrounding normal tissue.

[0007] Electron beam therapy, a type of radiation therapy used to treat tumors, is more effective than X-ray therapy. High radiation levels are present in the skin, which is the surface of the human body, and in the deep layers below the skin (e.g., 1-5 cm below the skin). It can deliver radiation dose.

[0008] In addition, the amount of radiation irradiated to normal tissue deeper than the treatment target is minimized. It has the advantage of being miniaturizable.

[0009] However, conventional electron beam therapy can only treat the planar area of ​​the treatment target, and the uterus When it is necessary to enter a narrow passage such as in the case of cancer, or when it is necessary to enter a narrow passage such as in the case of oral cancer, the electron beam is irradiated from the linear range. If irradiation is required in a bending direction to a part that is in a blind spot area, treatment may be impossible. There was a limit to what could be done.

[0010] In addition, the size of the tumor and the degree of progression of the disease vary depending on the location of the treatment target, and the radiation dose However, with conventional electron beam therapy, it is difficult to adjust the radiation dose depending on the position. There were drawbacks.

[0011] In particular, electron intraopera In the case of tive radiation therapy (electron IORT), For breast cancer, brain tumors, etc., the surface of the treatment target is spherical or U-shaped, and the front Minimally incisional surgery, laparoscopic / thoracoscopic surgery for organs such as the prostate, lungs, liver, pancreas, and colon , the difficulty of performing electron beam therapy in deep spaces through narrow passages in robotic surgery, etc. There was.

[0012] 1 and 2 are cross-sectional views illustrating the operation of a conventional electron beam therapy device. FIG. 1 shows an electron beam output unit 10, an electron scattering unit 20, a first applicator (electron a applicator / cone) 30, skin and treatment target. It includes an output section 10, an electron scattering section 20, a second applicator 40, skin and a treatment target.

[0013] First, in FIG. 1, an electron beam output unit 10 generates, accelerates, and outputs an electron beam. The electron scattering unit 20 located below the line output unit 10 receives this signal and scatters the electrons. It emits multiple electron beams.

[0014] The first applicator 30 located below the electron scattering unit 20 scatters the electrons scattered by the electron scattering unit 20. The electron beam is guided by the application of multiple electron beams, and the electron beam is not emitted outside the electron beam therapy device. Shield it like this.

[0015] The multiple electron beams guided through the first applicator 30 penetrate the skin and the treatment target. is irradiated.

[0016] At this time, among the multiple electron beams irradiated, as shown in FIG. 1, there are electron scattering units 20 and There is a problem that a large number of electron beams are absorbed by the first applicator 30, resulting in an output loss. It was.

[0017] Taking such power loss into consideration, the electron beam must reach the treatment target with a certain intensity or more. To do this, the electron beam output unit 10 may require a large amount of power.

[0018] In addition, as shown in Figure 1, there are many electron beams that reach the skin and subcutaneous tissue other than the treatment target. The problem is that radiation exposure to normal tissues is harmful to the patient's body. There was.

[0019] Furthermore, according to FIG. 2, unlike FIG. 1, the width of the second applicator 40 is too narrow to fit the treatment target. The target is not guided and irradiated to the entire area, but only to a part of it. However, there was a limitation in that electron beam therapy was insufficient. Summary of the Invention [Problem to be solved by the invention]

[0020] The present invention has been made in view of the above circumstances, and its object is to provide a therapeutic agent for treating a patient's body. When it is necessary to penetrate deep subcutaneous tissue, spherical curved surfaces, or narrow passages, Even when electron beam irradiation is required to reach blind spots outside the linear irradiation range of the electron beam, Magnetically adjustable electron beam therapy based on electron pencil beam that allows treatment while adjusting the direction and dose The present invention aims to provide a medical device and system.

[0021] The problems to be solved by the present invention are not limited to the problems mentioned above, and Further problems will be clearly understood by those skilled in the art from the following description. [Means for solving the problem]

[0022] The magnetic tuning of the electron pencil beam substrate according to the present invention to achieve the above technical object is as follows. The electron beam therapy device includes an electron beam output unit that generates, accelerates, and outputs an electron beam, and a The catheter is connected to an electron beam output unit and receives the electron beam output from the electron beam output unit. a catheter portion that passes through a hollow tunnel of the catheter; a magnetic field generating unit that generates a magnetic field for refracting the electron beam passing through the electron beam output unit; a joint drive unit that provides the force unit, the catheter, and the magnetic field generating unit with a degree of freedom of movement; and the catheter portion is configured to move and rotate the catheter in response to a control by a control unit. The angle can be adjusted.

[0023] At this time, the catheter section adjusts the position of the catheter in response to the control of the control section. While fixed at a certain depth, the refraction angle of the magnetic field generating unit is adjusted to target the treatment. The distribution of the irradiated electron beam can be adjusted.

[0024] The catheter unit controls the magnetic field generating unit to the catheter in response to the control of the control unit. The radiation is irradiated to the treatment target by moving the heater up and down, left and right, and rotating it. The distribution of the electron beam can be adjusted.

[0025] On the other hand, the electron beam output unit can output a pencil beam-shaped electron beam.

[0026] The magnetic field generating unit includes a permanent magnet, an electromagnet, and the permanent magnet at both ends of one side of the catheter. A first magnetic pole of any one of the hybrid forms in which a permanent magnet and an electromagnet are used together, and That is, the magnetic field generating unit can be configured in the form of a permanent magnet. In this case, the positions of the first and second magnetic poles and the distance between the first and second magnetic poles are adjusted. The refraction angle of the electron beam can be adjusted by the above. In this case, the pulsed electromagnet generates a magnetic field synchronized with the electron beam pulse. The refraction angle of the electron beam can be adjusted by adjusting the strength and direction of the magnetic field.

[0027] In addition, the present invention provides an electron pencil beam substrate for achieving the above-mentioned technical object. The magnetically regulated electron beam therapy system generates and accelerates electron beams and outputs them in the form of a pencil beam. The output electron beam is passed through the hollow tunnel of the catheter and irradiated onto the treatment target. and a remote control for remotely controlling the electron beam therapy device. a control unit for controlling the electron beam therapy device and a power supply unit for supplying a power supply voltage required for the electron beam therapy device in response to the control of the control unit; and a source unit, and the electron beam therapy device is configured to move the catheter in response to control by the control unit. The catheter can be driven by adjusting the movement and rotation angle.

[0028] At this time, the control unit controls the energy intensity, dose, speed and output timing of the electron beam. The strength, direction and output timing of the magnetic field generated by the magnetic field generating unit in the electron beam therapy device can be controlled.

[0029] The control unit may also control the magnetic field while the position of the catheter is fixed at a certain depth. The refraction angle of the generating section is adjusted to adjust the distribution of the electron beam irradiated onto the treatment target. can be controlled.

[0030] Furthermore, the control unit controls the magnetic field generation unit to move the catheter up and down, left and right, and rotate The electron beam moves together with the target and is controlled to adjust the distribution of the electron beam irradiated onto the treatment target. Can be controlled.

[0031] The magnetic field generating unit includes a permanent magnet, an electromagnet, and the permanent magnet at both ends of one side of the catheter. A first magnetic pole of any one of the hybrid forms in which a permanent magnet and an electromagnet are used together, and That is, the magnetic field generating unit can be configured in the form of a permanent magnet. In this case, the positions of the first and second magnetic poles and the distance between the first and second magnetic poles are adjusted. The refraction angle of the electron beam can be adjusted by the above. In this case, the pulsed electromagnet generates a magnetic field synchronized with the electron beam pulse. The refraction angle of the electron beam can be adjusted by adjusting the strength and direction of the magnetic field.

[0032] Further, the electron beam therapy device is configured to: The electron beam can be applied to the module through the electron beam output unit. It is Noh. [Effects of the Invention]

[0033] According to the present invention, the electron scattering section and applicator are not required, thereby reducing losses or leakage. Therefore, if the same electron beam output is the target, the electron beam output section This reduces the power consumption and improves the output of the electron beam when the same power consumption is used. This has the effect of making it possible to

[0034] In addition, it can detect not only flat areas of the patient's body, but also deep subcutaneous areas and spherical curved areas. This makes it possible to perform electron beam therapy in the targeted area of ​​treatment, and allows medical professionals to This provides the effect of enabling accurate and appropriate electron beam therapy while adjusting the radiation dose.

[0035] Furthermore, since a pencil beam of electrons is generated, the size of the space requiring a magnetic field is small. This allows the magnetic field generator to be miniaturized, enabling treatment to be performed in a narrow space inside the patient's body. This has the effect of enabling the device to enter.

[0036] In addition, when used during radiation therapy during surgery, the reduction of leakage electron beams will improve patient and medical outcomes. The risk of radiation exposure to workers is reduced, and the increased output of the electron beam reduces radiation exposure during surgery. This has the effect of shortening the treatment time.

[0037] The effects of the present invention are not limited to those mentioned above, and further effects not mentioned include: The following description will be clear to those skilled in the art. [Brief explanation of the drawings]

[0038] [Figure 1] 10A and 10B are cross-sectional views illustrating the operation of a conventional electron beam therapy device. [Figure 2] 10A and 10B are cross-sectional views illustrating the operation of a conventional electron beam therapy device. [Figure 3] 1 is a schematic diagram of an electron pencil beam-based magnetically regulated electron beam therapy system according to the present invention; [Figure 4] 1 is a schematic cross-sectional view illustrating the operation of an electron pencil beam-based magnetically adjusted electron beam therapy device according to the present invention; [Figure 5] 5 is a diagram showing an experimental model fabricated for the magnetically adjusted electron beam therapy apparatus 100 shown in FIG. 4 and a curved treatment target. FIG. [Figure 6] 5A to 5C are cross-sectional views showing various modes of electron beams irradiated onto a planar treatment target a and a curved treatment target b by vertical movement of a magnetic field generating unit 140 in the magnetically adjusted electron beam therapy apparatus shown in FIG. 4. [Figure 7] 5A to 5C are cross-sectional views showing various modes of electron beams irradiated onto a treatment target by the left and right movement of a magnetic field generating unit 140 in the magnetically adjusted electron beam therapy apparatus shown in FIG. 4. [Figure 8] 5A to 5C are cross-sectional views showing various modes of electron beams irradiated onto a planar treatment target a and a curved treatment target b depending on the refraction angle of the magnetic field generating unit 140 in the magnetically adjusted electron beam therapy device shown in FIG. 4. [Figure 9a] 5 is a diagram showing, from multiple angles, the state in which the magnetically adjusted electron beam therapy device shown in FIG. 4 is manufactured into a modular form and a magnetic field generating unit is attached. [Figure 9b] 5 is a diagram showing, from multiple angles, the state in which the magnetically adjusted electron beam therapy device shown in FIG. 4 is manufactured into a modular form and a magnetic field generating unit is attached. [Figure 9c]5 is a diagram showing, from multiple angles, the state in which the magnetically adjusted electron beam therapy device shown in FIG. 4 is manufactured into a modular form and a magnetic field generating unit is attached. [Figure 10] FIG. 5 is a diagram showing that an electron beam can be refracted at multiple angles by a magnetic field using the electron beam output unit 110, catheter 130, and magnetic field generating unit 140 shown in FIG. [Figure 11a] FIG. 9 is a diagram showing the traces of the electron beam displayed on the subject 400 as a result of the experiment shown in FIG. 8. [Figure 11b] FIG. 9 is a diagram showing the traces of the electron beam displayed on the subject 400 as a result of the experiment shown in FIG. 8. [Figure 11c] FIG. 9 is a diagram showing the traces of the electron beam displayed on the subject 400 as a result of the experiment shown in FIG. 8. DETAILED DESCRIPTION OF THE INVENTION

[0039] The advantages and features of the present invention and the manner in which they are achieved are described in detail below in conjunction with the accompanying drawings. However, the present invention will be elucidated with reference to the embodiments disclosed below. However, the present invention is not limited to the above and may be embodied in various different forms. The examples will be provided so that the disclosure of the present invention will be complete and easy for ordinary skilled in the art to which the present invention pertains. The present invention is defined by the appended claims. It is only defined by

[0040] The terms used in this specification are intended to describe the embodiments and are not intended to limit the present invention. In this specification, the singular includes the plural unless specifically stated otherwise. As used in the specification, "comprises" and / or "comprises" "rising" refers to the presence or addition of one or more other elements in addition to the element being mentioned. The same reference numerals refer to the same elements throughout the specification, and the like are used interchangeably with "and / or "includes each and every combination of one or more of the listed elements. Although "first," "second," etc. are used to describe various components, Of course, the components are not limited by these terms. Therefore, the following terms are used to distinguish one component from another. It goes without saying that one component may also be a second component within the technical concept of the present invention.

[0041] Unless otherwise defined, all terms (including technical and scientific terms) used herein are used in a way that can be commonly understood by those skilled in the art to which the present invention pertains. In addition, terms defined in commonly used dictionaries are not expressly defined. Unless otherwise stated, it should not be interpreted ideally or excessively.

[0042] Spatially relative terms such as "below," "beneath," and " "lower", "above", "upper", etc. are not illustrated. As shown in the figure, it is used to easily describe the correlation between one component and another. Spatially relative terms may be used in conjunction with the illustrated orientation and may be configured in use or operation. It should be understood that the terms encompass different orientations of the elements. When flipping a component, it is recommended to use the "below" or "beneath" position of the other component. Components described as "neat" are placed "above" other components. Thus, the exemplary term "below" includes an orientation of both below and above. The components can also be oriented in other directions, which allows for spatially relative The general terms can be interpreted in terms of orientation.

[0043] Hereinafter, embodiments of the present invention will be described in detail with reference to the accompanying drawings.

[0044] FIG. 3 shows a schematic diagram of the electron pencil beam-based magnetically regulated electron beam therapy system according to the present invention. 1 is a schematic diagram of the configuration of an electron beam therapy device 100, a control unit 200, and a power supply unit 300.

[0045] The electron beam therapy device 100 includes an electron beam output unit 110, a catheter unit 120, and a catheter 13. 0, a magnetic field generating unit 140, and a joint driving unit 150.

[0046] Referring to FIG. 3, the electron pencil beam-based magnetically adjusted electron beam therapy system according to the present invention is The system can be briefly explained as follows:

[0047] The electron beam therapy device 100 generates and accelerates a pencil beam of electrons, and The radiation is passed through 130 hollow tunnels and directed to the treatment target.

[0048] The control unit 200 is located apart from the electron beam therapy device 100 and controls the electron beam therapy device 100 and the power supply unit 3 It is a user terminal that can remotely control the 00 and has input means such as a keyboard and mouse and a display. It is equipped with output means such as a play unit.

[0049] That is, the control unit 200 controls the energy intensity of the electron beam output from the electron beam output unit 110, The dose, speed, and output timing are generated from the magnetic field generating unit 140 in the electron beam therapy device 100. The strength, direction and output timing of the magnetic field are controlled.

[0050] The power supply unit 300 responds to the control of the control unit 200 to supply the power supply voltage required for the electron beam therapy apparatus 100. Supply pressure.

[0051] FIG. 4 illustrates the operation of the electron pencil beam-based magnetically regulated electron beam therapy device according to the present invention. 1 is a schematic cross-sectional view illustrating an electron beam output unit 110, a catheter unit 120, a catheter 130, a magnetic field generating unit 140, including the skin and the treatment target.

[0052] FIG. 5 shows the electron beam therapy device 100 shown in FIG. 4 and the curved treatment target T. A photograph of an experimental model showing an electron beam output unit 110, a catheter unit 120, and a catheter 130. , a magnetic field generating unit 140 and a treatment target model.

[0053] In the treatment target model, the U-shaped white area at the bottom represents the area inside the patient's body. The yellow-green area T within the white area represents the area requiring radiation therapy. This is a model of the target.

[0054] FIG. 6 shows the vertical movement of the magnetic field generating unit 140 in the magnetically adjusted electron beam therapy apparatus 100 shown in FIG. The various patterns of electron beams irradiated onto the flat treatment target a and the curved treatment target b are 1 is a cross-sectional view of the magnetic field generating units 140-1 to 140-6, the skin, and the treatment target. include.

[0055] FIG. 7 shows the left and right movement of the magnetic field generating unit 140 in the magnetic adjustment electron beam therapy apparatus 100 shown in FIG. 10A and 10B are cross-sectional views of various aspects of an electron beam being irradiated onto a treatment target by a magnetic field generator; The living parts 140-1' to 140-3' include skin and a treatment target.

[0056] FIG. 8 shows the results of the electron beam therapy using the magnetic field generator 140 in the magnetically adjusted electron beam therapy apparatus shown in FIG. The electron beam is irradiated onto the flat treatment target a and the curved treatment target b in various forms. 14 is a cross-sectional view of the magnetic field generating units 140-7 and 140-8, the skin, and the treatment target.

[0057] 3 to 8, the magnetically adjustable electron beam control device for the electron pencil beam according to the present invention is The configuration and function of each component of the treatment device will be briefly described below.

[0058] The electron beam output unit 110 generates, accelerates, and outputs an electron beam.

[0059] The catheter part 120 is connected to the lower part of the electron beam output part 110 on one side (upper side) and to the lower part of the electron beam output part 110 on the other side (lower side). The catheter 130 is connected to the side of the catheter 130, and receives the electron beam output from the electron beam output unit 110. and passes it through the hollow tunnel 135 of the catheter 130.

[0060] The magnetic field generating unit 140 is connected to one side (lower side) of the catheter 130. A magnetic field is generated to refract the electron beam passing through the hollow tunnel 135 .

[0061] The joint drive unit 150 is connected at one side to the electron beam output unit 110. This provides the freedom of movement of the electric conductor 130 and the magnetic field generating unit 140 .

[0062] At this time, the catheter section 120 responds to the control of the control section 200 to The catheter 130 is driven by adjusting the movement and rotation angle.

[0063] 9a to 9c show the magnetically adjusted electron beam therapy device shown in FIG. 4, which is manufactured in a modular form. 9a is a diagram showing the magnetic field generating unit attached at various angles, and FIG. 9b is a diagram showing the magnetic adjustment unit shown in FIG. The position of the magnetic field generating part of the electron beam therapy device is set at a predetermined (or already set) angle. 9b shows the state where the upper part is photographed downward at a predetermined (or already set) angle. Figure 9c shows the state where the lower part of the magnetically adjusted electron beam therapy device is photographed from the front. The device includes a catheter 130 and a magnetic field generating unit 140, and the magnetic field generating unit 140 It includes first and second magnetic poles 141 and 142 .

[0064] FIG. 10 shows the electron beam output unit 110, the catheter 130, and the magnetic field generating unit 140 shown in FIG. This shows that electron beams can be refracted at various angles by a magnetic field using The electron beam output unit 110, the catheter 130, the magnetic field generating unit 140, and the subject 400 are included. .

[0065] FIG. 11 shows the experimental results shown in FIG. 10, and the electron beam traces displayed on the subject 400. This is a photo.

[0066] 3 to 11, the magnetically adjusted electron beam of the electron pencil beam base according to the present invention is shown. The treatment device will be described in detail below.

[0067] In FIG. 3, an electron beam output unit 110 generates an electron beam in the shape of a pencil beam. The electron beam is accelerated and output.

[0068] In this case, the energy of the electron beam can be set to 1 to 15 MeV, and the diameter can be set to 0.1 to 3 cm. It can be set.

[0069] The catheter unit 120 is connected to the bottom of the electron beam output unit 110. The output electron beam is applied to adjust the movement and rotation angle of the catheter 130, and a magnetic field is generated. The refraction angle of the raw portion 140 is adjusted.

[0070] The catheter 130 has a hollow tunnel 135, which is a cylindrical empty space in the center. It is connected to the lower part of the catheter part 120 and responds to the control of the catheter part 120 as shown in FIG. The electron beam passes through the rotating motion.

[0071] At this time, the catheter 130 is in a modular form and is driven independently of the electron beam output unit 110. They can be moved independently or can be fixed integrally to the electron beam output unit 110 and move up and down together. You can also move around while doing other things.

[0072] In addition, in order to reduce scattering of the electron beam passing through the inside of the catheter 130, The gas composition can be changed to, for example, helium gas or vacuum.

[0073] The magnetic field generating unit 140 is connected to one end of the catheter 130 and controls the catheter unit 120. Electron beams passing through the interior space of catheter 130 to adjust the angle of refraction in response. A magnetic field is generated to refract the light.

[0074] The electron beam whose refraction angle is adjusted by the magnetic field generated by the magnetic field generating unit 140 is shown in FIG. In this way, the electron beam is irradiated uniformly to various areas of the treatment target, and the distribution of the electron beam irradiation is adjusted. .

[0075] At this time, the magnetic field generating unit 140 moves together with the up and down movement of the catheter 130. The distribution of electron beam irradiation can be adjusted from the catheter 130, and the position of the catheter 130 can be fixed at a certain depth. The refraction angle can be adjusted in this state to adjust the distribution of electron beam irradiation.

[0076] That is, as shown in FIG. 6(a), the treatment target is present on the surface of the patient's body part. In some cases (e.g., skin cancer, large organ surgery, etc.), the catheter 130 may be moved up and down. The position of the magnetic field generating unit 140 varies from the first depth to the third depth 140-1 to 140-3. By irradiating the electron beam through the planar shape of the treatment target, Treatment can be carried out uniformly.

[0077] In addition, as shown in Figure 6(b), the treatment target is located at a specific depth from the patient's subcutaneous tissue. If the tumor is located on a spherical curved surface at a certain position (e.g., breast cancer, brain tumor, etc.), the catheter 130 By the vertical movement of the magnetic field generating unit 140, the position of the magnetic field generating unit 140 is changed to the fourth depth 140-4 to the sixth depth 140-6. 6, electron beam irradiation is performed at a constant rate, so that all areas of the treatment target are uniformly irradiated. Treatment can be performed.

[0078] Alternatively, as shown in FIG. 7, the catheter 130 may be moved left and right to change the position of the magnetic field generating unit 140. The position changes from the first position to the third position 140-1' to 140-3', and the magnetic field generated by the magnetic field generating unit 140 The amount of radiation to be delivered is lower than at least one of the standards already established, or The electron beam is irradiated by adjusting the dose to a higher level than the normal dose, or by avoiding certain areas. Therefore, the treatment target area with a flat (or curved) shape can be treated with different intensities at different positions. Treatment can be performed.

[0079] Alternatively, as shown in Figure 8(a), when the treatment target is on the surface of the patient's skin, Even if the position of the catheter 130 is fixed at the already set depth 140-7, The electron beam is irradiated while adjusting the refraction angle of the magnetic field generating unit 140 in various ways. This allows uniform treatment to be performed on all areas of the treatment target having a planar shape.

[0080] Also, as shown in Figure 8(b), the treatment target is positioned at a specific depth from the patient's subcutaneous tissue. Even if the catheter 130 is on a spherical curved surface in the position, the position of the catheter 130 is already set. While the depth 140-8 is fixed, the bending angle of the magnetic field generating unit 140 is adjusted in various ways. By irradiating the electron beam from the surface, the entire treatment target with a spherical curved surface is Treatment can be performed uniformly over the area.

[0081] This allows for sufficient electron beam treatment deep under the skin and on spherically curved surfaces of the patient's body. This allows for the medical professional to target the entire or partial area of ​​the therapeutic area. This allows electron beam therapy to be performed accurately and appropriately while adjusting the radiation dose.

[0082] At this time, in order to secure sufficient treatment space, balloons and pumps are placed in the space close to the treatment target. It is also possible to attach auxiliary medical devices such as plastic polyhedrons.

[0083] Additionally, due to the risk of radiation exposure to medical personnel, radiation therapy during surgery is generally not recommended. During surgery, medical staff must be in a separate space from the patient, The longer the radiation therapy time, the greater the risk to the patient. This may shorten radiation treatment time during treatment and reduce risks to the patient.

[0084] The magnetic field generating unit 140 may be a permanent magnet, an electromagnet, or a hybrid magnet in which both the permanent magnet and the electromagnet are used. It can be configured in any one of the following hybrid forms:

[0085] In this case, if the magnetic field generating unit 140 is configured in the form of a permanent magnet, the electron beam output unit 110 The refraction angle of the electron beam can be adjusted by adjusting the velocity of the electron beam generated by the electron beam generating element.

[0086] In addition, when the magnetic field generating unit 140 is configured in the form of a permanent magnet, the first and second magnetic poles (ma The positions of the first and second magnetic poles 141, 142 are adjusted to 142 is moved out of the path of the electron beam, The influence of the magnetic field in the field generating unit 140 can be reduced.

[0087] Furthermore, when the magnetic field generating unit 140 is configured in the form of a permanent magnet, the first and second magnetic poles (ma The refraction angle of the electron beam is adjusted by adjusting the distance between the magnetic poles 141 and 142. That is, the distance between the first and second magnetic poles 141 and 142 can be adjusted. Increasing the distance reduces the strength of the magnetic field, and decreasing the distance increases the strength of the magnetic field.

[0088] On the other hand, when the magnetic field generating unit 140 is composed of an electromagnet, it is used as a pulsed electromagnet. The magnetic field is generated by synchronizing with the laser beam, and the strength and direction of the generated magnetic field are adjusted to control the electric field. The angle of refraction of the sagittal line can be adjusted.

[0089] This allows for a reduction in heat generation when the same magnetic field is generated, and under the same heat generation conditions In this case, the magnetic field power can be increased.

[0090] The strength of the magnetic field generated by the magnetic field generating unit 140 is set to 0.1 to 1.0 Tesla. can.

[0091] The control unit 200 not only controls the operations of the electron beam output unit 110 and the magnetic field generation unit 140, but also The moving distance and speed of the catheter 130, the rotation angle and angular velocity, the bending of the magnetic field generating unit 140, Adjust the angle of refraction to deliver a preset radiation dose to each part of the treatment target. This allows for the adjustment of radiation dose depending on the location of the affected area, which is not possible with conventional electron beam therapy equipment. Electron beams for various shapes and positions, including spherical, narrow passages, and curved areas Treatment of

[0092] The joint driving unit 150 is connected to the electron beam output unit 110 on one side and to the power supply unit 300 on the other side. The electron beam output unit 110, the catheter 130, and the magnetic field generating unit 140 are connected so that they move organically. This provides the freedom to:

[0093] As described above, the magnetically regulated electron beam therapy apparatus of the present invention has the same functions as the conventional electron beam therapy apparatus. Since the electron scattering unit and the applicator that were previously required are no longer required, the electron beam generated in the electron beam output unit 110 can be Among the electron beams that enter the device, there are no electron beams that are absorbed by the electron scattering section and the applicator, and they are lost. Therefore, when the same output is targeted, the electron beam output unit 110 can This reduces the power consumption, and improves the output of the electron beam when the same power consumption is used. .

[0094] The electron beam therapy device 100 of the present invention is based on an electron pencil beam. Large overall area (e.g. 40x40cm) 2 Conventional electron beam therapy simultaneously treats In contrast to conventional electron beam therapy, the pencil beam-based electron beam therapy of the present invention can be applied to a small unit area (e.g., 0.5×0.5cm 2 After concentrating on the following positions, irradiate the following positions in order to treat the entire area. It is characterized by its treatment.

[0095] In addition, the radiation dose absorption rate in the conventional electron scattering area is around 50%, and at the same time, The area covered is 6,400 times larger than conventional treatment (40x40cm) 2 Pencil beam treatment surface area Considering that the area decreases by a multiple of 0.5 × 0.5 cm2, each unit area (0.5 × 0.5 cm2) m 2 ) it can be seen that the treatment speed increases by about 10,000 times compared to conventional methods.

[0096] Therefore, the output of general radiation therapy is 0.1 Gy / s, and under special conditions it is 10 Gy Considering that the electron beam pencil beam is about / s, the electron beam therapy of the present invention is based on The device 100 is capable of outputting 1,000-100,000 Gy / s, and can output more than 40 Gy / s. The flash effect known to occur during treatment is obtained at a speed of By lowering a part of the device, it can be made smaller and more portable, which makes it easier to release the device during surgery. It can also be used in radiation therapy.

[0097] The electron pencil beam can enter a narrow space via the catheter 130. The electron pencil beam is irradiated with a small diameter, so the size of the space where a magnetic field is required is small. The magnetic field generating unit 140 can be miniaturized, and the distance between the catheter and the magnetic field generating unit can be reduced. This also makes it possible to enter narrow spaces inside the patient's body.

[0098] As shown in FIGS. 9a to 9c, the electron beam therapy device 100 of the present invention has an electron beam output 5. It can be fabricated as a stand-alone device including the unit 110, or can be integrated into existing electronic devices, as shown in FIG. It can also be manufactured as a modular device that can receive electron beams at a distance from the electron beam generator. There is an advantage to being there.

[0099] 9a to 9c, one side of the catheter 130 having a certain shape First and second magnetic poles 141 and 142 of a magnetic field generating unit 140 are attached to both ends, respectively.

[0100] As shown in FIG. 10, the electron beam therapy device 100 of the present invention is integrated with an electron beam output unit 110. The electron beam is generated in this state, and the control unit 200 controls the refraction angle of the magnetic field generating unit 140 in various ways. Electron beams can be irradiated while

[0101] As shown in FIG. 10, when the electron beam therapy device 100 is integrated with the electron beam output unit 110, The rotation of the catheter 130 and the magnetic field generating unit 140 is controlled by the catheter unit 120. The downward movement involves the entire electron beam modular therapy device 100 moving together.

[0102] As shown in Figure 11a, when no magnetic field is applied, the electron beam traces displayed on the subject is displayed at the first position P1, which is the lowest position.

[0103] As shown in FIG. 11b, the magnetic field generating unit 140 generates a magnetic field in response to the control of the control unit 200. If so, it is displayed at the second position P2, which is an intermediate height.

[0104] As shown in FIG. 11c, the refraction angle of the magnetic field generating unit 140 is adjusted by the control of the control unit 200. and / or adjust the position of the magnetic field generating unit 140 to increase the height at which the electron beam is irradiated by 1. When the electron beam is irradiated after moving 5 cm upward, the electron beam reaches the third position P3, which is the highest position. You can see that it is displayed.

[0105] Thus, the present invention is directed to the treatment target in the patient's body, which is deep subcutaneous tissue and spherical curvature. When it is necessary to enter a narrow passage or a surface area, it is a blind spot area outside the direct irradiation range of the electron beam. Even when electron beam irradiation is required for a specific area, treatment can be performed by adjusting the direction and dose of the electron beam. The present invention provides an electron beam therapy device and system based on an electron pencil beam.

[0106] This eliminates the need for an electron scattering unit and an applicator, minimizing the loss or leakage of electron beams. Therefore, when the same electron beam output is targeted, the power consumed by the electron beam output section is Therefore, the output of the electron beam can be improved when the same power consumption is used.

[0107] In addition, it can detect not only flat areas of the patient's body, but also deep subcutaneous areas and spherical curved areas. This allows electron beam therapy to be performed in the area of ​​the treatment target that medical professionals intend. This allows electron beam therapy to be performed accurately and appropriately while adjusting the radiation dose.

[0108] Furthermore, since a pencil beam of electrons is generated, the size of the space requiring a magnetic field is small. This allows the magnetic field generator to be miniaturized, enabling treatment to be performed in a narrow space inside the patient's body. The device becomes accessible.

[0109] In addition, when used during radiation therapy during surgery, the reduction of leakage electron beams will improve patient and medical outcomes. The risk of radiation exposure to workers is reduced, and the increased output of the electron beam reduces radiation exposure during surgery. Treatment time is reduced.

[0110] The embodiments of the present invention have been described above with reference to the accompanying drawings. A person skilled in the art would understand that the present invention can be realized without changing the technical idea or essential features thereof. Therefore, the above-described embodiment can be embodied in the following specific forms: It should be considered in all respects as illustrative and not restrictive.

Claims

1. an electron beam output unit that outputs an electron beam; a catheter portion that receives the electron beam output from the electron beam output portion and passes the electron beam through a hollow tunnel of the catheter; a magnetic field generating unit that generates a magnetic field for refracting the electron beam passing through the hollow tunnel of the catheter; a joint driving unit having one side connected to the electron beam output unit and the other side connected to a power supply unit, and configured to move the electron beam output unit, the catheter, and the magnetic field generating unit relative to the power supply unit; Including, The catheter portion adjusting the movement and rotation angle of the catheter in response to control by a control unit; The magnetic field generating unit can be moved together with the catheter in response to control by the control unit to adjust the distribution of the electron beam irradiated onto the treatment target. A magnetically regulated electron beam therapy device based on an electron pencil beam.

2. The catheter portion 2. The electron pencil beam-based magnetically regulated electron beam therapy device of claim 1, characterized in that the distribution of the electron beams irradiated to the treatment target is adjusted by adjusting the refraction angle of the magnetic field generator while fixing the position of the catheter at a certain depth in response to the control of the control unit.

3. The electron beam output unit includes:

2. The electron beam pencil beam-based magnetically regulated electron beam therapy device according to claim 1, wherein the electron beam is output in the form of a pencil beam.

4. The magnetic field generating unit is 3. The electron pencil beam-based magnetically regulated electron beam therapy device according to claim 2, wherein a first magnetic pole and a second magnetic pole of any one of a permanent magnet, an electromagnet, and a hybrid in which both the permanent magnet and the electromagnet are used are respectively attached to both ends of one side of the catheter.

5. The magnetic field generating unit is 5. The electron pencil beam-based magnetically adjustable electron beam therapy device according to claim 4, wherein, in the case of the permanent magnet form, the refraction angle of the electron beam is adjusted by adjusting the positions of the first and second magnetic poles and the distance between the first and second magnetic poles.

6. The magnetic field generating unit is 5. The electron pencil beam-based magnetically controlled electron beam therapy device of claim 4, wherein, in the case of the electromagnet form, a pulsed electromagnet generates a magnetic field synchronized with the electron beam pulse, and the refraction angle of the electron beam is adjusted by adjusting the strength and direction of the generated magnetic field.

7. an electron beam therapy device that irradiates the output electron beam onto a treatment target by passing the output electron beam through a hollow tunnel in a catheter; a control unit that is spaced apart from the electron beam therapy apparatus and remotely controls the electron beam therapy apparatus; a power supply unit that supplies a power supply voltage required for the electron beam therapy device in response to control by the control unit; Including, the electron beam therapy device adjusts the movement and rotation angle of the catheter in response to control by the control unit; The control unit The electron beam therapy device is characterized by controlling the energy dose and output timing of the electron beam, and the output timing of the magnetic field generated by the magnetic field generating unit in the electron beam therapy device. A magnetically controlled electron beam therapy system based on an electron pencil beam.

8. The control unit 8. The electron pencil beam-based magnetically regulated electron beam therapy system of claim 7, wherein the refraction angle of the magnetic field generator is adjusted while the position of the catheter is fixed at a certain depth, thereby controlling the distribution of the electron beam irradiated to the treatment target.

9. The control unit 8. The electron pencil beam-based magnetically regulated electron beam therapy system of claim 7, wherein the magnetic field generator controls the catheter to move in accordance with its vertical, horizontal and rotational movements, thereby adjusting the distribution of the electron beams irradiated onto the treatment target.

10. The magnetic field generating unit is The electron beam pencil beam-based magnetically regulated electron beam therapy system of claim 7, wherein a first magnetic pole and a second magnetic pole of any one of a permanent magnet, an electromagnet, and a hybrid in which both the permanent magnet and the electromagnet are used are respectively attached to both ends of one side of the catheter.

11. The magnetic field generating unit is 11. The electron pencil beam-based magnetically adjustable electron beam therapy system of claim 10, wherein, in the case of the permanent magnet, the refraction angle of the electron beam is adjusted by adjusting the positions of the first magnetic pole and the second magnetic pole and the distance between the first magnetic pole and the second magnetic pole.

12. The magnetic field generating unit is 11. The electron pencil beam-based magnetically controlled electron beam therapy system of claim 10, wherein, in the case of the electromagnet form, a pulsed electromagnet generates a magnetic field synchronized with the electron beam pulse, and the refraction angle of the electron beam is adjusted by adjusting the strength and direction of the generated magnetic field.

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