A method for manually locking inserted line take-up equipment to prevent premature retraction

Abstract

A fluid transfer device including a housing, a distal introducer portion configured to penetrate a needleless access connector of a vascular access device, and a wheel member rotatable relative to the housing and operably coupled to the probe to advance and retract the probe through the distal introducer portion. The fluid transfer device also includes a connector member disposed proximate to the distal introducer portion, the connector member including a pair of opposing distal clip portions, a pair of opposing proximal clip portions, and a locking member. The locking member is operably coupled to the wheel member and configured to prevent actuation of at least a portion of the connector member when the wheel member is rotated to a first position and to allow actuation of at least a portion of the connector member when the wheel member is rotated to a second position.

Description

[Technical field]

[0001] The present disclosure relates generally to blood collection devices and associated assemblies, systems, and methods for use in drawing blood via existing vascular access devices (VADs), such as peripheral intravenous catheters (PIVCs). Specifically, the blood collection devices of the present disclosure are configured to prevent premature retraction and / or removal of the device. [Background technology]

[0002] This application claims priority to U.S. Provisional Patent Application No. 63 / 326,001, entitled “Device for Manually Locking an Inserted Line Draw Device to Prevent Premature Retraction,” filed March 31, 2022, which is incorporated herein by reference.

[0003] Vascular access devices (VADs), such as catheters, are commonly used to infuse fluids into a patient's vascular system. For example, catheters can be used to infuse normal saline, various medications, or total parenteral nutrition. In some instances, the VAD may be an over-the-needle peripheral venous catheter (PIVC).

[0004] In addition to infusion, VADs may also be used to withdraw blood from a patient, although they are not typically designed and optimized for this purpose. In light of the challenges associated with withdrawing blood from a VAD, fluid transfer devices have been developed to mitigate potential catheter collapse, reduced blood flow due to debris accumulating on or within the catheter, etc. Examples of such fluid transfer devices are presented and described in U.S. Patent Application Publication No. 2021 / 0290905, which is incorporated herein by reference.

[0005] 1 illustrates a fluid transfer device 18 similar to that shown and described in U.S. Patent Application Publication No. 2021 / 0290905. The fluid transfer device 18 is configured to be releasably coupled to an adapter 14 having a needleless access connector 16, which is coupled to a catheter adapter 10 having a catheter 12 extending therefrom and configured for vascular access. The fluid transfer device 18 includes a housing 20 having a connector 24, a distal introducer portion 26 disposed at a distal end portion, and a vacuum tube receiver 28 disposed at a proximal end portion, the vacuum tube receiver 28 configured to receive a blood collection device, such as, for example, a BD VACUTAINER® blood collection tube, to draw a blood sample from a patient via the VAD. Although not shown, fluid transfer device 18 includes an elongated probe (e.g., a nickel titanium wire) that can be selectively advanced distally beyond the distal end of adapter 14, catheter adapter 10, and catheter 12 to provide a fluid channel that allows blood to be drawn into a blood collection device within vacuum tube receptacle 28. Advancement of the probe of fluid transfer device 18 is controlled by a rotatable wheel 22 within housing 20, such that a clinician can use their thumb to rotate wheel 22 in a first direction to advance the probe and in an opposite, second direction to retract (retract) the probe.

[0006] Prior to deployment of the probe, the fluid transfer device 18 is coupled to the adapter 14 and the distal introducer portion 26 is inserted through the septum of the needleless access connector 16. Once the distal introducer portion 26 has been inserted sufficiently distally into the needleless access connector 16, a lever lock clip-shaped connector 24 is configured to clip onto the adapter 14 and secure the fluid transfer device 18 in place. Once secured, the probe can be advanced from the fluid transfer device 18 by rotation of the wheel 22.

[0007] Typically, the probe is retracted into the fluid transfer device 18 by rotation of the wheel 22 in the opposite direction after blood collection, at which point the connector 24 can be disconnected from the adapter 14 by pinching the proximal clip portions 5A, 25B together to release the "alligator clip" distal connection of the connector 24 from the adapter 14. However, in some cases, a clinician or other user may disconnect the connector 24 from the adapter 14 and retract the distal introducer portion 26 while the probe remains advanced within the adapter 14, catheter adapter 10, and / or catheter 12. Such premature retraction and / or removal of the fluid transfer device 18 may result in undesirable exposure to blood or other bodily fluids and / or damage to the probe.

[0008] The subject matter claimed herein is not limited to embodiments that solve the shortcomings or that operate only in environments such as those described above. Rather, this background is only provided to describe one example technology area where some embodiments described herein may be practiced. Summary of the Invention [Means for solving the problem]

[0009] In one embodiment of the present disclosure, a fluid transfer device for delivering a probe to a patient's vasculature is disclosed. The fluid transfer device includes a housing, a distal introducer portion disposed at a distal end portion of the housing and configured to penetrate a needleless access connector of a vascular access device, and a wheel member rotatable relative to the housing, the wheel member operably coupled to the probe to advance and retract the probe through the distal introducer portion based on a direction of rotation of the wheel member. The fluid transfer device also includes a connector member disposed proximate the distal introducer portion and configured for releasable connection to at least one surface of the needleless access connector, the connector member including a pair of opposing distal clip portions and a pair of opposing proximal clip portions. The fluid transfer device further includes a locking member operably coupled to the wheel member and configured to prevent actuation of at least one of the pair of opposing proximal clip portions upon rotation of the wheel member to a first position and to allow actuation of at least one of the pair of opposing proximal clip portions upon rotation of the wheel member to a second position.

[0010] In some embodiments, the wheel member includes a clocking member, and the locking member is operably coupled to the clocking member.

[0011] In some embodiments, the locking member includes an arm coupled to the clocking member.

[0012] In some embodiments, one end of the arm includes a post configured to ride within a cam groove formed in the clocking member.

[0013] In some embodiments, the locking member includes a ring member that is longitudinally slidable over at least a portion of the housing.

[0014] In some embodiments, the locking member includes a biasing member configured to bias the locking member in one direction.

[0015] In some embodiments, the fluid transfer device further includes a rack member and a pinion gear, the pinion gear operably coupled to the wheel member and the rack member coupled to the locking member to longitudinally displace the locking member based on a direction of rotation of the wheel member.

[0016] In some embodiments, the locking member includes at least one tab, the at least one tab being displaceable by a wire operably coupled to the wheel member.

[0017] In some embodiments, the locking member includes at least one proximal arm member and the wheel member includes at least one slot disposed in a radial surface of the wheel member, the at least one slot having a size and configuration to accommodate at least a portion of the at least one proximal arm member.

[0018] In some embodiments, the locking member further includes at least one living hinge coupled at a first end to at least one of the pair of opposing proximal clip portions and coupled at a second end to the at least one proximal arm member.

[0019] In some embodiments, the locking member further includes a ramped distal member.

[0020] In some embodiments, the locking member is manually displaceable by a user.

[0021] In some embodiments, the locking member includes a distal block portion and a proximal button portion, the proximal button portion configured as a user interface.

[0022] In another aspect of the present disclosure, a fluid transfer device for needleless delivery of a probe to a patient's vasculature is disclosed. The fluid transfer device includes a housing, a distal introducer portion disposed at a distal end portion of the housing and configured to penetrate a needleless access connector of a vascular access device, and a wheel member rotatable relative to the housing, the wheel member operably coupled to the probe to advance and retract the probe through the distal introducer portion based on a direction of rotation of the wheel member. The fluid transfer device also includes a connector member disposed proximate the distal introducer portion and configured for releasable connection to at least one surface of the needleless access connector, and a locking member configured to prevent disconnection of the connector member from the needleless access connector when the wheel member is rotated to a first position and to allow disconnection of the connector member when the wheel member is rotated to a second position.

[0023] In some embodiments, the locking member includes a sleeve member.

[0024] In some embodiments, the sleeve member is configured to extend over at least a portion of the connector member when the wheel member is rotated to the first position.

[0025] In some embodiments, at least a portion of the locking member is configured to extend beneath at least a portion of the connector member when the wheel member is in the first position.

[0026] In some embodiments, the wheel member further includes a pair of opposing slots on opposing sides of the wheel member, and the locking member includes a pair of opposing inward protrusions on a proximal portion of the connector member, the pair of opposing inward protrusions configured to engage with the pair of opposing slots when the wheel member is rotated to the second position.

[0027] In some embodiments, the apparatus further includes a protruding member extending from at least one side of the probe, the protruding member configured to allow movement of the locking member based on a position of the probe within the housing.

[0028] In some embodiments, the locking member is manually displaceable by a user, the locking member including a distal block portion and a proximal button portion, the proximal button portion configured as a user interface.

[0029] It should be understood that both the foregoing general description and the following detailed description are exemplary and explanatory, and are not intended to limit the invention as claimed. It should be understood that the various embodiments are not limited to the arrangements and instruments shown. It should also be understood that the embodiments may be combined or other embodiments may be utilized, and structural changes may be made without departing from the scope of the various embodiments of the present invention, unless otherwise claimed. Therefore, the following detailed description should not be taken in a limiting sense. Exemplary embodiments are described with additional specificity and detail in the accompanying drawings. [Brief description of the drawings]

[0030] [Figure 1] FIG. 1 is a perspective view of a prior art vascular access arrangement and fluid transfer device. [Diagram 2] FIG. 1 is a side cross-sectional view of a fluid transfer device according to one embodiment of the present disclosure. [Diagram 3] FIG. 13 is a top cross-sectional view of a fluid transfer device according to another aspect of the present disclosure. [Figure 4] FIG. 4 is a side cross-sectional view of the fluid transfer device of FIG. 3. [Diagram 5] FIG. 13 is a top cross-sectional view of a fluid transfer device according to another aspect of the present disclosure. [Figure 6] 6 is a side cross-sectional view of the fluid transfer device of FIG. 5. [Figure 7]FIG. 13 is a side view of a clocking member having an external cam for use with a wheel member according to an aspect of the present disclosure. [Figure 8] FIG. 8 is an end view of the clocking member with external cam of FIG. 7. [Figure 9] FIG. 2 is a cross-sectional side view of a fluid transfer device according to another embodiment of the present disclosure in a first orientation. [Figure 10] 10 is a side cross-sectional view of the fluid transfer device of FIG. 9 in a second configuration. [Figure 11] FIG. 13 is a top cross-sectional view of a fluid transfer device according to another aspect of the present disclosure. [Figure 12] FIG. 12 is a side view of a wheel member and rack and pinion arrangement for use with the fluid transfer device of FIG. [Figure 13] FIG. 13 is a top view of a fluid transfer device according to another aspect of the present disclosure. [Figure 14] FIG. 14 is a perspective cross-sectional view of the fluid transfer device of FIG. 13. [Figure 15] FIG. 2 is a side view of a wheel member according to one embodiment of the present disclosure. [Figure 16] 1 is a partial cross-sectional side view of a fluid transfer device according to another aspect of the present disclosure. [Figure 17] FIG. 17 is a perspective view showing the wire member and tab configuration of the fluid transfer device of FIG. 16. [Figure 18] 17 is a side view of the connector member and tab arrangement of the fluid transfer device of FIG. 16. [Figure 19] FIG. 13 is a top cross-sectional view of a fluid transfer device according to another aspect of the present disclosure. [Figure 20] 11 is a side cross-sectional view of a locking member for use with a fluid transfer device according to another aspect of the present disclosure. FIG. [Figure 21] 13 is a side cross-sectional view of another locking member for use with a fluid transfer device according to another aspect of the present disclosure. FIG. [Figure 22] 13 is a side cross-sectional view of another locking member for use with a fluid transfer device according to another aspect of the present disclosure. FIG. [Figure 23]13 is a side cross-sectional view of another locking member for use with a fluid transfer device according to another aspect of the present disclosure. FIG. [Figure 24] 13 is a side view of another locking member for use with a fluid transfer device according to another aspect of the present disclosure. FIG. [Diagram 25] FIG. 13 is a side view of a ring-shaped locking member for use with a fluid transfer device according to another aspect of the present disclosure. [Figure 26] FIG. 26 is an end view of the ring-shaped locking member of FIG. 25. [Figure 27] 1 is a partial cross-sectional side view of a fluid transfer device according to another embodiment of the present disclosure in a first orientation. [Figure 28] 28 is a partial cross-sectional side view of the fluid transfer device of FIG. 27 in a second configuration. [Figure 29] FIG. 2 is a top view of a fluid transfer device according to another embodiment of the present disclosure in a first configuration. [Diagram 30] FIG. 30 is a top view of the fluid transfer device of FIG. 29 in a second configuration. [Diagram 31] FIG. 2 is a partial cross-sectional view of a fluid transfer device according to another embodiment of the present disclosure in a first configuration. [Diagram 32] FIG. 2 is a partial cross-sectional view of a fluid transfer device according to another embodiment of the present disclosure in a first configuration. [Diagram 33] 33 is a partial cross-sectional view of the fluid transfer device of FIG. 32 in a second configuration. [Diagram 34] FIG. 2 is a partial cross-sectional view of a fluid transfer device according to another embodiment of the present disclosure in a first configuration. [Diagram 35] FIG. 35 is a partial cross-sectional view of the fluid transfer device of FIG. 34 in a second configuration. [Diagram 36] FIG. 2 is a partial cross-sectional view of a fluid transfer device according to another embodiment of the present disclosure in a first configuration. [Figure 37] FIG. 37 is a partial cross-sectional view of the fluid transfer device of FIG. 36 in a second configuration. [Figure 38] FIG. 13 is a partial top view of a fluid transfer device according to another aspect of the present disclosure. [Figure 39] FIG. 39 is a top view of the proximal button portion of the fluid transfer device of FIG. 38. [Diagram 40]FIG. 2 is a partial cross-sectional view of a fluid transfer device according to another embodiment of the present disclosure in a first configuration. [Diagram 41] 1A-1C are top views of a fluid transfer device according to another embodiment of the present disclosure in a first and second configuration. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0031] The following description is provided to enable a person skilled in the art to make and use the described embodiments contemplated for carrying out the invention. However, various modifications, equivalents, variations, and alternatives will remain readily apparent to those skilled in the art. All such modifications, variations, equivalents, and alternatives are intended to be within the spirit and scope of the present disclosure.

[0032] In the following description, the terms "upper", "lower", "right", "left", "longitudinal", "horizontal", "top", "bottom", "transverse", "longitudinal", and derivatives thereof, refer to the present invention as oriented in the drawings. It should be understood, however, that the present invention may assume various alternative modifications unless expressly stated to the contrary. It should also be understood that the specific devices illustrated in the accompanying drawings and described in the following specification are merely exemplary embodiments of the present invention. Accordingly, specific dimensions and other physical characteristics relating to the embodiments disclosed herein are not to be considered as limiting.

[0033] In this disclosure, a distal end of a component or device means the end furthest from a user's hand when the component or device is in a position for use, i.e., when a user is holding the fluid transfer device while preparing for use or during use, and a proximal end means the end closest to the user's hand. Similarly, in this application, the terms "distally" and "distally" mean the direction toward the connector portion of the fluid transfer device, and the terms "proximally" and "proximally" mean the direction opposite to the direction of the connector.

[0034] Although not shown or described herein, it should be understood that the fluid transfer devices described below may be utilized to withdraw blood from any suitable vascular access device, such as, for example, the BD Nexiva™ Closed IV Catheter System, the BD Catena™ Catheter System, the BD Venflon™ Prosafe Shield IV Catheter System, the BD Neoflon™ IV Cannula System, the BD Insight™ Autoguard™ BC Shield IV Catheter System, or other suitable vascular access device.

[0035] Referring to FIG. 2, a fluid transfer device 100 according to one embodiment of the present disclosure is illustrated. The fluid transfer device 100 includes a housing 102 and a wheel member 104. Although not shown in FIG. 2, the wheel member 104 interacts with an elongated flexible probe to advance or retract (retract) the probe through a distal introducer portion 106 located at a distal end portion of the housing 102. That is, rotation of the wheel member 104 in a first direction advances the probe through the distal introducer portion 106, allowing the probe to enter the patient's vasculature when the fluid transfer device 100 is coupled to a vascular access device. Conversely, rotation of the wheel member 104 in an opposite second direction retracts the probe through the distal introducer portion 106, ultimately removing the probe from the patient's vasculature.

[0036] In some embodiments, the probe is configured as a guidewire (e.g., a nickel titanium wire). However, in other embodiments, the probe may be configured as any flexible member or instrument that can be advanced through a catheter, such as, for example, a tube, a secondary catheter, one or more sensors, an obturator, or any combination thereof. Additionally, in some embodiments, the distal introducer portion 106 is configured as a blunt plastic cannula that can be used with a needleless connector of a vascular access device. However, in other embodiments, the distal introducer portion 106 may be configured as a male luer connector and / or a needleless connector (NFC), a needle access connector (PRN), a luer access port (or female luer), or a needle or cannula that can access a septum, such as, for example, a BD Nexiva™ needle septum.

[0037] The fluid transfer device 100 also includes a connector member 108 configured to selectively couple the fluid transfer device 100 to a needleless access connector, for example, of an adapter coupled to a vascular access device. The connector member 108 is configured as an alligator clip type connector, and opposing distal clip portions 109A, 109B allow the fluid transfer device 100 to be secured to a surface of the needleless access connector. The pair of proximal clip portions 110A, 110B are sized and configured to be clamped or otherwise manipulated by a user. Manipulation of the proximal clip portions 110A, 110B causes the distal clip portions 109A, 109B to pivot away from one another, thereby disengaging the distal clip portions 109A, 109B from engagement with the needleless access connector. In some embodiments, the proximal clip portions 110A, 110B may have inward protrusions 111A, 111B to provide a stop or limit to the inward movement of each of the proximal clip portions 110A, 110B relative to the housing 102. Additionally, although not shown, in some embodiments the proximal clip portions 110A, 110B may include textured surfaces and / or indicators to provide an indication to a user regarding the functionality of the connector member 108.

[0038] 2, the fluid transfer device 100 further includes an arm member 112 having a distal end portion coupled to (or otherwise associated with) a sleeve member 116 and a proximal end portion extending to a clocking member 120 rotatable with the wheel member 104. The clocking member 120 includes clocking protrusions 122, 124 which may interact with a retainer 118 located at or near the proximal end portion of the arm member 112.

[0039] With the wheel member 104 in the first position and the probe retracted into the housing 102, the arm member 112 is held by the clocking lug 122 of the clocking member 120 and the sleeve member 116 is retracted proximally away from the connector member 108. In this position (shown in FIG. 2), the proximal clip portions 110A, 110B of the connector member 108 can be clamped to release the distal clip portions 109A, 109B from engagement with the needleless access connector, thus allowing the fluid transfer device 100 to be removed from engagement with the needleless access connector.

[0040] Conversely, when the wheel member 104 is rotated toward the second position and the flexible probe is advanced through the distal introducer portion 106, the clocking protrusion 122 of the clocking member 120 releases the arm member 112, allowing the sleeve member 116 to move distally along the housing 102 toward the connector member 108. In some embodiments, a biasing member 114 (e.g., a spring) may be provided to bias the sleeve member 116 distally. In this manner, the sleeve member 116 is configured to be positioned substantially below at least the inward protrusions 111A, 111B of the proximal clip portions 110A, 110B when the wheel member 104 is rotated toward the second position. The sleeve member 116 has a size and configuration that substantially limits inward movement of the proximal clip portions 110A, 110B when clamped.

[0041] By limiting / preventing the inward movement of the proximal clip portions 110A, 110B, the user cannot release the distal clip portions 109A, 109B from engagement with the needleless access connector and therefore cannot remove the fluid transfer device 100 from the needleless access connector when the flexible probe is in the advanced position. However, upon rotating the wheel member 104 back to the first position to retract the flexible probe, the arm member 112 can again interact with the clocking protrusions 122 of the clocking member 120 and overcome the biasing force of the biasing member 114 to pull the sleeve member 116 proximally away from the connector member 108. Upon rotating the wheel member 104 such that the flexible probe is at or near a retracted position within the distal introducer portion 106 and / or housing 102, the sleeve member 116 is correspondingly positioned away from the connector member 108, again allowing inward movement of the proximal clip portions 110A, 110B, thereby allowing disengagement of the distal clip portions 109A, 109B from the needle-free access connector, thus allowing removal of the fluid transfer device 100 from the needle-free access connector when the flexible probe is at or near the retracted position. In this manner, premature removal of the fluid transfer device 100 from the needle-free access connector can be substantially avoided.

[0042] 3 and 4, a fluid transfer device 150 is illustrated according to another aspect of the present disclosure. Similar to the fluid transfer device 100 described above with respect to FIG. 2, the fluid transfer device 150 includes a housing 152 and a wheel member 154. The wheel member 154 is configured to interact with an elongated flexible probe (not shown) to advance and retract the probe through a distal introducer portion 157 located at a distal end portion of the housing 152.

[0043] The fluid transfer device 150 also includes a connector member 158 configured to selectively couple the fluid transfer device 150 to a needleless access connector, for example, of an adapter coupled to a vascular access device (not shown). The connector member 158 is configured as an alligator clip type connector, with opposing distal clip portions allowing the fluid transfer device 150 to be secured to a surface of the needleless access connector. The pair of proximal clip portions 159A, 159B are sized and configured to allow the distal clip portions to be pinched or otherwise manipulated by a user to pivot away from one another to release the connector member 158 from engagement with the needleless access connector. In some embodiments, the proximal clip portions 159A, 159B may each have an inward protrusion to provide a stop or limit to the inward movement of each of the proximal clip portions 159A, 159B relative to the housing 152. Additionally, although not shown, in some embodiments, the proximal clip portions 159A, 159B may include textured surfaces and / or indicators to provide an indication to a user regarding the functionality of the connector member 158.

[0044] The fluid transfer device 150 further includes an L-shaped arm member movably coupled to the housing 152, the arm member including an elongated first portion 160 and a second portion 166 disposed at a proximal end of the first portion 160. A distal end portion of the first portion 160 extends toward the connector member 158 while a proximal end portion of the second portion 166 extends toward a clocking member 156 rotatable with the wheel member 154. The clocking member 156 includes a clocking protrusion 155 that may interact with a proximal end portion of the second portion 166. The first portion 160 further includes slots 161A, 161B formed therethrough, the slots 161A, 161B being sized and configured to receive fixed pins 164A, 164B extending from the housing 152. Slots 161A, 161B allow longitudinal movement of the L-shaped arm members relative to housing 152, and pins 164A, 164B provide limits to the longitudinal movement of the L-shaped arm members.

[0045] When the wheel member 154 is in the first position and the probe is retracted into the housing 152, a stop 169 may hold the second portion 166 of the L-shaped arm member in a retracted (retracted) position in which the distal end portion of the first portion 160 is retracted proximally away from the connector member 158. In this position, the proximal clip portions 159A, 159B of the connector member 158 are clamped together to release the distal clip portions from engagement with the needleless access connector, thus allowing the fluid transfer device 150 to be removed from engagement with the needleless access connector.

[0046] Meanwhile, upon rotating the wheel member 154 towards the second position to advance the flexible probe through the distal introducer portion 157, the clocking protrusion 155 of the clocking member 156 releases the second portion 166 from engagement with the stop 169, allowing the L-shaped arm member including the first portion 160 to move distally along the housing 152 and towards the connector member 158 relative to the pins 164A, 164B. In some embodiments, a biasing member 168 (e.g., a spring) may be provided to bias the L-shaped arm member in the distal direction. In this manner, upon rotating the wheel member 154 towards the second position, the distal end portion of the first portion 160 of the L-shaped arm member is configured to be located substantially below the proximal clip portions 159A, 159B and has a size and configuration that substantially limits the inward movement of the proximal clip portions 159A, 159B when clamped. It should be appreciated that although only a single L-shaped arm member is shown in FIGS. 3 and 4, in some embodiments a second arm member may be provided on the opposite side of the housing 152 .

[0047] To pinch the proximal clip portions 159A, 159B to remove the fluid transfer device 150 from engagement with the needleless access connector, the user must first return the probe to a fully or substantially retracted position within the housing 152 by rotating the wheel member 154 back toward the first position. Once the probe is retracted, the user then manually returns the L-shaped arm member to engagement with the stop 169 by sliding a thumb grip 162 on the exterior of the housing 152 proximally, thereby allowing the distal end portion of the first portion 160 of the L-shaped arm member to move proximally away from the connector member 158. This position of the L-shaped arm member is only possible when the probe is substantially or fully retracted, allowing the user to pinch the proximal clip portions 159A, 159B to remove the fluid transfer device 150 from engagement with the needleless access connector.

[0048] 5 and 6, a fluid transfer device 170 according to another embodiment of the present disclosure is illustrated. The fluid transfer device 170 includes a housing 172 and a wheel member 174. The wheel member 174 is configured to interact with an elongated flexible probe (not shown) to advance and retract the probe through a distal introducer portion 187 located at a distal end portion of the housing 172. The fluid transfer device 170 further includes a connector member 185 configured to selectively couple the fluid transfer device 170 to a needleless access connector of, for example, an adapter coupled to a vascular access device (not shown). The connector member 185 is configured as an alligator clip type connector, with opposing distal clip portions allowing the fluid transfer device 170 to be secured to a surface of the needleless access connector, and a pair of proximal clip portions 186A, 186B sized and configured to release the connector member 185 from engagement with the needleless access connector by a user's pinching or other manipulation.

[0049] Fluid transfer device 170 further includes an L-shaped arm member movable relative to housing 172, the arm member having an elongated first portion 182 and a second portion 180 disposed at a proximal end of first portion 182. A distal end portion of first portion 182 extends toward a connector member 185 and is coupled at its distal end to a locking member 188. Locking member 188 may be any suitable shape, for example, ring-shaped, H-shaped, etc.

[0050] A proximal end portion of second portion 180 extends to a clocking member 176 rotatable with wheel member 174, the clocking member 176 including a clocking protrusion 178. In addition, clocking member 176 includes a cam groove 177 formed therein such that a pin or other member on the proximal end portion of second portion 180 is configured to interact with cam groove 177.

[0051] First portion 182 further includes slots 183A, 183B formed therethrough that are sized and configured to receive fixed pins 184A, 184B extending from housing 172. Slots 183A, 183B allow longitudinal movement of the L-shaped arm members relative to housing 172, and pins 184A, 184B provide a limit to longitudinal movement of the L-shaped arm members.

[0052] When the wheel member 174 is in the first position and the probe is retracted into the distal introducer portion 187 and housing 172, the clocking member 176 is rotated to advance the second portion 180 of the L-arm member along the cam groove 177 and hold the L-arm member in a retracted (retracted) position. In this retracted position, the locking member 188 is retracted proximally away from the connector member 185, thereby pinching the proximal clip portions 186A, 186B of the connector member 185 and allowing the distal clip portions to be released from engagement with the needleless access connector, thus allowing the fluid transfer device 170 to be removed from engagement with the needleless access connector.

[0053] Conversely, when the wheel member 174 is rotated toward the second position and the flexible probe is advanced through the distal introducer portion 187, the second portion 180 of the L-shaped arm member advances along the cam groove 177 of the correspondingly rotating clocking member 176, causing the first portion 182 and locking member 188 to move distally along the housing 172 relative to the pins 184A, 168B and toward the connector member 185.

[0054] Thus, in this "advanced" position of the wheel member 174, the locking member 188 is configured to be located substantially below the proximal clip portions 186A, 186B, substantially limiting inward movement of the proximal clip portions 186A, 186B when clamped. To clamp the proximal clip portions 186A, 186B and remove the fluid transfer device 170 from engagement with the needleless access connector, the user must first rotate the wheel member 174 back toward the first position to return the probe to a fully or substantially retracted (retracted) position within the housing 172. This rotation of the wheel member 174 results in a corresponding rotation of the clocking member 176, and thus a proximal movement of the L-arm member due to the interaction between the second portion 180 and the cam groove 177 of the clocking member 176. Thus, retraction of the probe via the wheel member 174 results in proximal displacement of the locking member 188 away from the connector member 185, thereby enabling a user to clamp the proximal clip portions 186A, 186B to remove the fluid transfer device 170 from engagement with the needleless access connector.

[0055] It should be understood that as an alternative to a clocking member incorporating a cam groove as shown and described above with respect to Figures 5 and 6, a clocking member associated with a wheel member may utilize an external cam. For example, with reference to Figures 7 and 8, a clocking member 190 for use with a wheel member (not shown) of a fluid transfer device may incorporate an external cam surface 192 and a clocking protrusion 194. The external cam surface 192 may interact with an L-shaped arm member, for example, to longitudinally move a connector locking member relative to an alligator clip type connector.

[0056] 9 and 10, a fluid transfer device 200 according to another embodiment of the present disclosure is illustrated. The fluid transfer device 200 includes a housing 202 and a wheel member 204. The wheel member 204 is configured to interact with an elongated flexible probe 218 (shown in FIG. 10) to advance and retract the probe 218 through a distal introducer portion 216 located at a distal end portion of the housing 202. The fluid transfer device 200 may further include a connector member 214. The connector member 214 may be configured to selectively couple the fluid transfer device 200 to a needleless access connector 220 of an adapter coupled to a vascular access device (not shown), for example. The connector member 214 is configured as a collet-type connector, and opposing distal clip portions 215A, 215B may secure the fluid transfer device 200 to a surface of the needleless access connector 220.

[0057] The fluid transfer device 200 further includes an arm member 208 that is movable relative to the housing 202. The arm member 208 includes a rack member 210 disposed on a proximal surface portion, while a distal portion of the arm member 208 is coupled to a sleeve member 212. The rack member 210 is configured to engage a pinion gear member 206 that is rotatable with the wheel member 204. When the wheel member 204 is in a first position and the probe is retracted into the distal introducer portion 216 and the housing 202 (as shown in FIG. 9 ), the rack member 210 of the arm member 208 interacts with the pinion gear member 206 to pull the arm member 208 and sleeve member 212 proximally away from the connector member 214. In this retracted position, the distal clip portions 215A, 215B flex outwardly to allow release of engagement of the distal clip portions 215A, 215B with the needleless access connector, and thus removal of the fluid transfer device 200 from engagement with the needleless access connector 220.

[0058] However, upon rotation of the wheel member 204 towards the second position to advance the flexible probe 218 through the distal introducer portion 216, the rack member 210 advances along the pinion gear member 206 to move the arm member 208 and the sleeve member 212 in a distal direction, with the sleeve member 212 at least partially encircling the distal clip portions 215A, 215B. Thus, in this "advanced" position of the wheel member 204, the sleeve member 212 is configured to substantially prevent outward movement of the distal clip portions 215A, 215B, thereby preventing removal of the fluid transfer device 200 from the needle-free access connector 220 when the probe 218 is in the "advanced" position.

[0059] To remove the fluid transfer device 200 from engagement with the needle-free access connector 220, the user must rotate the wheel member 204 toward the first position to return the probe to a fully or substantially retracted position within the housing 202. This rotation of the wheel member 204 results in a corresponding rotation of the pinion gear member 206 and thus, due to the interaction between the pinion gear member 206 and the rack member 210, a proximal movement of the arm member 208 and the sleeve member 212. Thus, retraction of the probe 218 via the wheel member 204 results in a proximal displacement of the sleeve member 212 away from the connector member 214, thereby allowing disengagement and removal of the fluid transfer device 200 from the needle-free access connector 220.

[0060] 11 and 12, a fluid transfer device 230 according to another embodiment of the present disclosure is shown. The fluid transfer device 230 includes a housing 232 and a wheel member 234. The wheel member 234 is configured to interact with an elongated flexible probe (not shown) to advance and retract the probe through a distal introducer portion 248 located at a distal end portion of the housing 232.

[0061] The fluid transfer device 230 further includes a connector member 244 configured to selectively couple the fluid transfer device 230 to a needleless access connector of, for example, an adapter coupled to a vascular access device (not shown). The connector member 244 is configured as an alligator clip type connector with opposing distal clip portions 246A, 246B allowing for securing the fluid transfer device 230 to a surface of the needleless access connector and a pair of proximal clip portions 245A, 245B sized and configured to release the connector member 244 from engagement with the needleless access connector by squeezing or otherwise manipulating the connector member 244 by a user.

[0062] The fluid transfer device 230 further includes a locking mechanism including a pinion gear member 236, a rack member 238, an arm member 240 coupled to a distal end of the rack member 238, and a locking ring 242. The pinion gear member 236 includes a plurality of teeth configured to mesh with corresponding teeth of the wheel member 234 as well as the plurality of teeth of the rack member 238. Thus, rotation of the wheel member 234 in a first direction results in rotation of the pinion gear member 236 in a second direction (opposite the first direction), resulting in longitudinal movement of the rack member 238.

[0063] Upon rotating the wheel member 234 to the first position to retract the probe into the distal introducer portion 248 and housing 232, the rack member 238 interacts with the pinion gear member 236 to pull the arm member 240 and locking ring 242 proximally away from the connector member 244. In this retracted (retracted) position, the locking ring 242 is pulled proximally away from the connector member 244, thereby pinching the proximal clip portions 245A, 245B of the connector member 244 and releasing the distal clip portions 246A, 246B from engagement with the needleless access connector, thereby allowing the fluid transfer device 230 to be removed from engagement with the needleless access connector.

[0064] Conversely, upon rotating the wheel member 234 to the second position to advance the flexible probe through the distal introducer portion 248, the rack member 238 interacts with the pinion gear member 236 to move the arm member 240 and the locking ring 242 distally toward the connector member 244 until the locking ring 242 is ultimately disposed beneath the proximal clip portions 245A, 245B. Thus, in this "advanced" position of the wheel member 234, the locking ring 242 is configured to substantially prevent inward movement (i.e., pinching) of the proximal clip portions 245A, 245B, thus preventing removal of the fluid transfer device 230 from the needleless access connector when the probe is in the "advanced" position.

[0065] 13 and 14, a fluid transfer device 250 according to another embodiment of the present disclosure is shown. The fluid transfer device 250 includes a housing 252 and a wheel member 254. The wheel member 254 is configured to interact with an elongated flexible probe (not shown) to advance and retract the probe through a distal introducer portion 264 located at a distal end portion of the housing 252. A connector member 260 is provided and configured to selectively couple the fluid transfer device 250 to a needleless access connector of, for example, an adapter coupled to a vascular access device (not shown). The connector member 260 is configured as an alligator clip type connector, with opposing distal clip portions 262A, 262B allowing the fluid transfer device 250 to be secured to a surface of the needleless access connector, and a pair of proximal clip portions 261A, 261B sized and configured to release the connector member 260 from engagement with the needleless access connector by pinching or otherwise manipulating the connector member 260 by a user.

[0066] The fluid transfer device 250 further includes a locking mechanism including a pinion gear member 255, a rack member 256, and a pair of segment gear members 258A, 258B. The pair of segment gear members 258A, 258B are disposed on opposing surfaces located on the sides of the rack member 256. The pinion gear member 255 includes a plurality of teeth configured to mesh with corresponding teeth of the wheel member 254 as well as the plurality of teeth of the rack member 256. Thus, rotation of the wheel member 254 in a first direction results in rotation of the pinion gear member 255 in a second direction opposite to the first direction, resulting in longitudinal movement of the rack member 256. Additionally, longitudinal movement of the rack member 256 also results in pivot-type movement of each of the segment gear members 258A, 258B.

[0067] Upon rotating the wheel member 254 to the first position to retract the probe into the distal introducer portion 264 and housing 252, the rack member 256 interacts with the pinion gear member 255 to move the rack member 256 proximally away from the connector member 260, which also causes the segmented gear members 258A, 258B to pivot inwardly away from the connector member 260. The pivoting of the segmented gear members 258A, 258B away from the connector member 260 pinches the proximal clip portions 261A, 261B of the connector member 260, allowing the distal clip portions 262A, 262B to be released from engagement with the needleless access connector, and thus allowing the fluid transfer device 250 to be removed from engagement with the needleless access connector.

[0068] Meanwhile, upon rotating the wheel member 254 towards the second position to advance the flexible probe through the distal introducer portion 264, the rack member 256 interacts with the pinion gear member 255 to pivot the segmented gear members 258A, 258B outwardly and towards the connector member 260 to position each portion of the segmented gear members 258A, 258B beneath the proximal clip portions 261A, 261B. Thus, in this "advanced" position of the wheel member 254, the segmented gear members 258A, 258B are configured to substantially prevent inward movement (i.e., pinching) of the proximal clip portions 261A, 261B, thus preventing removal of the fluid transfer device 250 from the needleless access connector when the probe is in the "advanced" position.

[0069] 15-18, components of a fluid transfer device according to another embodiment of the present disclosure are illustrated. The fluid transfer device includes a wheel member 300 disposed within a housing 301 having a distal end portion (i.e., nozzle) 309. As shown in FIG. 18, a connector member 310 may be provided at or near the distal end portion 309 to enable engagement of the fluid transfer device with a needleless access connector (not shown).

[0070] Additionally, the wheel member 300 may include a separate rotating member 302 that may be coupled to and configured to rotate with the wheel member 300. The rotating member 302 has a post member 304 extending laterally therefrom. Similarly, a wire 306 is provided having a first end coupled to the post member 304 and a second end coupled to one or more longitudinally slidable tabs 308 disposed at a distal end portion 309 of the housing 301.

[0071] Upon rotating the wheel member 300 to a first position to retract the flexible probe into the distal end portion 309 and housing 301, the wire 306 is at its maximum extension, allowing the tab 308 to remain in its distal-most position relative to the distal end portion 309. This distal-most position of the tab 308 allows the proximal clip portions 311A, 311B of the connector member 310 to be pinched together, releasing the distal clip portions 311A, 311B from engagement with the needleless access connector, and thus removing the fluid transfer device from engagement with the needleless access connector.

[0072] However, as shown in Figures 17 and 18, upon rotating the wheel member 300 towards the second position and advancing the flexible probe through the distal end portion 309 of the housing 301, the rotating member 302 correspondingly rotates, pulling the wire 306 by the post member 304 and displacing the tab 308 proximally. As the wheel member 300 advances to the second position, the tab 308 is ultimately positioned below the proximal clip portions 311A, 311B. Thus, in this "advanced" position of the wheel member 300, the tab 308 is configured to substantially prevent inward movement (i.e., pinching) of the proximal clip portions 311A, 311B, thus preventing removal of the fluid transfer device from the needleless access connector when the probe is in the "advanced" position.

[0073] Although not shown in Figures 15-18, it should be understood that the wire 306 may be configured to have sufficient column strength and / or support structure to enable the wire 306 to push the tab 308 back to a distal-most position relative to the distal end portion 309 when the wheel member 300 is rotated back toward the first position to retract the flexible probe.

[0074] 19, which illustrates a fluid transfer device 320 according to another aspect of the present disclosure. The fluid transfer device 320 includes a housing 322 and a rotatable wheel member 324. The wheel member 324 is configured to interact with an elongated flexible probe (not shown) to advance and retract the probe through a distal introducer portion (not shown) located at a distal end portion of the housing 322. The fluid transfer device 320 further includes a connector member 330 configured to selectively couple the fluid transfer device 320 to, for example, a needleless access connector of an adapter coupled to a vascular access device (not shown). The connector member 330 is configured as an alligator clip type connector, with opposing distal clip portions 332A, 332B enabling the fluid transfer device 320 to be secured to a surface of the needleless access connector 334, and a pair of proximal clip portions 331A, 331B sized and configured to release the connector member 330 from engagement with the needleless access connector by clamping or otherwise manipulating the connector member 330 by a user.

[0075] The fluid transfer device 320 also includes a locking mechanism including a linear actuator member 326 and a pair of post members 328A, 328B disposed at or near a distal end portion of the linear actuator member 326. The linear actuator member 326 is configured to be displaced longitudinally along the housing 322 by any suitable means that cooperates with rotation of the wheel member 324, such as, for example, a rack and pinion mechanism, a worm gear mechanism, or any other suitable mechanism.

[0076] In rotating the wheel member 324 to the first position to retract the probe into the distal introducer portion and housing 322, the linear actuator 326 interacts (either directly or indirectly) with the wheel member 324 to pull the posts 328A, 328B proximally away from the connector member 330, thus pinching the proximal clip portions 331A, 331B of the connector member 330 and releasing the distal clip portions 332A, 332B from engagement with the needleless access connector 334, allowing the fluid transfer device 320 to be removed from engagement with the needleless access connector 334. Meanwhile, in rotating the wheel member 324 towards the second position to advance the flexible probe through the distal introducer portion, the linear actuator 326 interacts (either directly or indirectly) with the wheel member 324 to move the posts 328A, 328B distally towards the connector member 330. This prevents the proximal clip portions 331A, 331B from being pinched inwardly when the probe is in the "advanced" position, preventing the fluid transfer device 320 from being removed from the needle-free access connector 334.

[0077] 20-26, various interfaces between connector members and "blocking" features configured to limit the use of the connector members according to aspects of the present disclosure are illustrated. Initially, FIG. 20 illustrates a portion of a fluid transfer device 350 having a housing 364, a distal introducer portion 363, and a connector member 360. The connector member 360 includes opposing distal clip portions 362A, 362B that allow the fluid transfer device 350 to be secured to a surface of a needleless access connector, and a pair of proximal clip portions 361A, 361B that are sized and configured to be pinched together by a user to release the connector member 360. A locking member 352 is provided on the fluid transfer device, and the locking member 352 has a protruding portion 354 that can prevent (or substantially prevent) the proximal clip portions 361A, 361B from being pinched together in certain configurations. In some embodiments, the locking member 352 may be configured as a ring and may be symmetrical. In other embodiments, the locking member may be asymmetric and / or may block only one of the two proximal clip portions.

[0078] 21 illustrates a fluid transfer device 370 according to another embodiment, which includes a locking member having a straight portion 372 and one or more angled surfaces 374. The angled surfaces 374 are configured to mimic the shape of corresponding surfaces of the proximal clip portions 361A, 361B.

[0079] 22, another embodiment of a fluid transfer device 380 is illustrated. The fluid transfer device 380 includes a locking member having a straight portion 382 and one or more protrusions 384. The protrusions 384 are positioned, dimensioned, and configured to mate with corresponding recesses 385A, 385B of the respective proximal clip portions 361A, 361B.

[0080] FIG. 23 shows a fluid transfer device 390 according to another embodiment, which includes a locking member having a straight portion 392 and one or more curved surfaces 394 configured to mimic the shape of corresponding curved inner surfaces of the proximal clip portions 361A, 361B.

[0081] 24, there is illustrated a locking member 400 according to another aspect of the present disclosure. The locking member 400 is not ring-shaped, but instead includes a pair of opposing posts 401A, 401B extending from a straight portion 402 to selectively block movement of a proximal clip portion (not shown).

[0082] 25 and 26 illustrate the locking member 410 configured as a ring-shaped member. It should be appreciated that the locking member 410 may be configured to extend around the distal end portion of the housing 364 to selectively block actuation of the connector member 360.

[0083] 27 and 28, a fluid transfer device 420 according to another aspect of the present disclosure is illustrated. The fluid transfer device 420 includes a housing 422 and a wheel member 424. The wheel member 424 is configured to interact with an elongated flexible probe (not shown) to advance and retract the probe through a distal introducer portion 429 located at a distal end portion of the housing 422. Also provided is a connector member 426 configured to selectively couple the fluid transfer device 420 to, for example, a needleless access connector of an adapter coupled to a vascular access device (not shown). The connector member 426 is configured as an alligator clip type connector, with opposing distal clip portions 428A, 428B enabling the fluid transfer device 420 to be secured to a surface of the needleless access connector, and a pair of proximal clip portions 427A, 427B sized and configured to release the connector member 426 from engagement with the needleless access connector by being clamped or otherwise manipulated by a user.

[0084] The fluid transfer device 420 further includes a locking mechanism including at least one living hinge member 431 coupled at a distal end thereof to at least one of the proximal clip portions 427A, 427B. The living hinge member 431 includes a proximal end portion 430, both of which are movable upon inward movement of the proximal clip portions 427A, 427B of the connector member 426.

[0085] Additionally, the wheel member 424 includes a slot 425 disposed in a radial surface thereof. The slot 425 is sized and configured to receive at least a portion of the proximal end portion 430 of the locking mechanism when the wheel member 424 is in a particular orientation. For example, as shown in FIGS. 27 and 28 , the proximal end portion 430 of the locking mechanism is substantially aligned with the slot 425 formed in the wheel member 424 upon rotation of the wheel member 424 to a first position to retract the probe into the distal introducer portion 429 and housing 422. Thus, when the proximal clip portions 427A, 427B of the connector member 426 are clamped, the living hinge member 431 pivots to guide the proximal end portion 430 into the slot 425, thereby fully clamping the proximal clip portions 427A, 427B and releasing the distal clip portions 428A, 428B from engagement with the needleless access connector, and thus releasing the fluid transfer device 420 from engagement with the needleless access connector. In addition, the spring-like action of the connector member 426 pulls the living hinge member 431 distally when the proximal clip portions 427A, 427B are released, thereby also allowing the proximal end portion 430 to be retracted away from the slot 425 when the proximal clip portions 427A, 427B are released by the user.

[0086] Conversely, although not shown, it should be understood that upon rotation of the wheel member 424 towards the second position to advance the flexible probe through the distal introducer portion 429, the proximal end portion 430 of the locking mechanism is not aligned with the slot 425 formed in the wheel member 424. In this position, upon clamping the proximal clip portions 427A, 427B of the connector member 426, the living hinge member 431 pivots to direct the proximal end portion 430 into the wheel member 424, but the proximal end portion 430 does not enter the slot 425 but instead is blocked by the radial surface of the wheel member 424, thereby preventing clamping of the proximal clip portions 427A, 427B from allowing release of the distal clip portions 428A, 428B. Thus, in this "advanced" position of the wheel member 424, a locking mechanism including the living hinge member 431 and the proximal end portion 430 interacts to substantially prevent inward movement (i.e., clamping) of the proximal clip portions 427A, 427B, thus preventing removal of the fluid transfer device 420 from the needleless access connector when the probe is in the "advanced" position.

[0087] Although the locking mechanism described above and shown in Figures 27 and 28 includes a living hinge member 431 and a proximal end portion 430, it should be understood that the locking mechanism is not so limited and may include, for example, a multi-part hinge instead of a living hinge, etc.

[0088] 29 and 30, a fluid transfer device 440 according to another aspect of the present disclosure is illustrated. The fluid transfer device 440 includes a housing 442 and a wheel member 444. The wheel member 444 is configured to interact with an elongated flexible probe (not shown) to advance and retract the probe through a distal introducer portion 452 located at a distal end portion of the housing 442. Similarly, a connector member 448 is provided and configured to selectively couple the fluid transfer device 440 to, for example, a needleless access connector of an adapter coupled to a vascular access device (not shown). The connector member 448 is configured as an alligator clip type connector, with opposing distal clip portions 450A, 450B enabling the fluid transfer device 440 to be secured to a surface of the needleless access connector, and a pair of proximal clip portions 449A, 449B sized and configured to release the connector member 448 from engagement with the needleless access connector by being clamped or otherwise manipulated by a user.

[0089] The fluid transfer device 420 further includes a locking mechanism including a proximal arm member 446 and a pair of distal arm members 447A, 447B pivotally coupled to the proximal arm member 446. The proximal arm member 446 is coupled to a wheel member 444 by any suitable mechanism (e.g., a rack and pinion mechanism, a worm gear mechanism, etc.), such that rotation of the wheel member 444 in either direction results in longitudinal displacement of the proximal arm member 446. In addition, the distal arm members 447A, 447B are configured to pivot relative to the proximal arm member 446 depending on the longitudinal position of the proximal arm member 446. That is, when the proximal arm member 446 is displaced in a proximal direction, the distal arm members 447A, 447B are configured to pivot inwardly (i.e., toward each other), while when the proximal arm member 446 is displaced in a distal direction, the distal arm members 447A, 447B are configured to pivot outwardly.

[0090] 29, when the wheel member 444 is rotated to a first position to retract the probe into the distal introducer portion 452 and the housing 442, the proximal arm member 446 is pulled proximally away from the connector member 448, thereby pivoting the distal arm members 447A, 447B inwardly relative to each other. Thus, when the proximal clip portions 449A, 449B of the connector member 448 are clamped, the distal arm members 447A, 447B do not act as a blocker. This allows the proximal clip portions 449A, 449B to be fully actuated to release the distal clip portions 450A, 450B from engagement with the needleless access connector, thereby allowing the fluid transfer device 440 to be removed from engagement with the needleless access connector.

[0091] 30, on the other hand, when the wheel member 444 is rotated toward the second position to advance the flexible probe through the distal introducer portion 452, the proximal arm member 446 is forced distally toward the connector member 448, thereby pivoting the distal arm members 447A, 447B outwardly relative to one another. In some embodiments, a wedge or ramp 454 is provided that contacts the ramp 454 as the proximal arm member 446 is pushed distally, urging the distal arm members 447A, 447B outward. Alternatively, in other embodiments, one or more springs may be coupled to each distal arm member 447A, 447B to urge the distal arm members 447A, 447B outwardly when the proximal arm member 446 is pushed distally. In this position, when the proximal clip portions 449A, 449B of the connector member 448 are clamped, the distal arm members 447A, 447B act as a blocker preventing the proximal clip portions 449A, 449B from being clamped to allow the distal clip portions 450A, 450B to be released. Thus, in this "advanced" position of the wheel member 444, a locking mechanism including the proximal arm member 446 and the pair of distal arm members 447A, 447B interact to substantially prevent inward movement (i.e., clamping) of the proximal clip portions 449A, 449B and thus, removal of the fluid transfer device 440 from the needleless access connector when the probe is in the "advanced" position.

[0092] 31 , a fluid transfer device 460 according to another embodiment of the present disclosure is illustrated. The fluid transfer device 460 includes a housing 462 and a wheel member 464. The wheel member 464 is configured to interface with an elongated flexible probe (not shown) to advance and retract the probe through a distal introducer portion 478 located at a distal end portion of the housing 462.

[0093] Also provided is a connector member 472 configured to selectively couple the fluid transfer device 460 to, for example, a needleless access connector of an adapter coupled to a vascular access device (not shown). The connector member 472 is configured as an alligator clip type connector with opposing distal clip portions 476A, 476B allowing the fluid transfer device 460 to be secured to a surface of the needleless access connector and a pair of proximal clip portions 473A, 473B sized and configured to release the connector member 472 from engagement with the needleless access connector by squeezing or otherwise manipulating the connector member 472 by a user. In some embodiments, the proximal clip portions 473A, 473B can include respective inward projections 474A, 474B.

[0094] The fluid transfer device 460 further includes a locking mechanism including an angled distal member 470 and an arm member 466, where the angled distal member 470 is biased in a distal direction via a biasing member 468 (e.g., a spring). As discussed further below, the angled surface of the angled distal member 470 is configured in some configurations to interact with at least the inward protrusions 474A, 474B of the proximal clip portions 473A, 473B to displace the angled distal member 470 and the arm member 466 in a proximal direction upon inward movement of the proximal clip portions 473A, 473B of the connector member 472.

[0095] The wheel member 464 includes a slot 465 disposed in a radial surface thereof. The slot 465 is sized and configured to receive at least a portion of the arm member 466 of the locking mechanism when the wheel member 464 is in a particular orientation. For example, when the wheel member 464 is rotated to a first position to retract the probe into the distal introducer portion 478 and the housing 462, at least a proximal portion of the arm member 466 of the locking mechanism is substantially aligned with the slot 465 formed in the wheel member 464. Thus, when the proximal clip portions 473A, 473B of the connector member 472 are clamped, the angled distal member 470 is displaced proximally against the biasing force of the biasing member 468, and the arm member 466 is also displaced proximally such that at least a portion of the arm member 466 enters the slot 465 of the wheel member 464. Such a configuration allows the proximal clip portions 473A, 473B to be fully clamped to release the distal clip portions 476A, 476B from engagement with the needleless access connector, and thus allow the fluid transfer device 460 to be removed from engagement with the needleless access connector.

[0096] Conversely, although not shown, it should be understood that upon rotating the wheel member 464 towards the second position to advance the flexible probe through the distal introducer portion 478, the arm member 466 of the locking mechanism is not aligned with the slot 465 formed in the wheel member 464. In this position, upon clamping the proximal clip portions 473A, 473B of the connector member 472, the angled distal member 470 is unable to displace proximally against the biasing force of the biasing member 468 and the arm member 466 of the locking mechanism is unable to enter the slot 465 and is blocked by the radial surface of the wheel member 464. This blocking of proximal displacement of the angled distal member 470 prevents the proximal clip portions 473A, 473B from being fully clamped to allow release of the distal clip portions 476A, 476B. Thus, in this "advanced" position of the wheel member 464, the locking mechanism including the angled distal member 470 and the arm member 466 interact to substantially prevent inward movement (i.e., clamping) of the proximal clip portions 473A, 473B, thus preventing removal of the fluid transfer device 460 from the needleless access connector when the probe is in the "advanced" position.

[0097] 32 and 33, a fluid transfer device 480 according to another aspect of the present disclosure is illustrated. The fluid transfer device 480 includes a housing 482 and a wheel member 484. The wheel member 484 is configured to interact with an elongated flexible probe (not shown) to advance and retract the probe through a distal introducer portion 493 located at a distal end portion of the housing 482. A connector member 490 is also provided and is configured to selectively couple the fluid transfer device 480 to, for example, a needleless access connector of an adapter coupled to a vascular access device (not shown). The connector member 490 is configured as an alligator clip style connector with opposing distal clip portions 492A, 492B allowing the fluid transfer device 480 to be secured to a surface of the needleless access connector and a pair of proximal clip portions 491A, 491B sized and configured to be pinched or otherwise manipulated by a user to release the connector member 490 from engagement with the needleless access connector. The proximal clip portions 491A, 491B include respective inward projections 494A, 494B.

[0098] Unlike the fluid transfer devices described above with respect to Figures 2-31 which include a separate locking mechanism for selectively preventing actuation of the connector members, the fluid transfer device 480 relies on a direct interaction between the proximal clip portions 491A, 491B and the wheel member 484 to selectively prevent (or allow) actuation of the connector members. Specifically, as shown in Figures 32 and 33, the wheel member 484 includes a pair of slots 486A, 486B on opposing sides thereof. It should be appreciated that, alternatively, in other embodiments, the slots 486A, 486B may be configured as multiple recesses or a single through hole extending entirely through the wheel member 484.

[0099] Each slot 486A, 486B is sized and configured to receive at least a portion of an inward projection 494A, 494B of the wheel member 484 when the wheel member 484 is in a particular orientation. For example, with reference to FIG. 32, when the wheel member 484 is rotated to a first position to retract the probe into the distal introducer portion 493 and housing 482, the inward projections 494A, 494B are substantially aligned with the slots 486A, 486B formed in the wheel member 484. Thus, when the proximal clip portions 491A, 491B of the connector member 490 are clamped, the inward projections 494A, 494B can at least partially enter the slots 486A, 486B. With such a configuration, the proximal clip portions 491A, 491B can be fully clamped to release the distal clip portions 492A, 492B from engagement with the needleless access connector, and thus the fluid transfer device 480 can be removed from engagement with the needleless access connector.

[0100] 33, however, upon rotating the wheel member 484 toward the second position to advance the flexible probe through the distal introducer portion 493, the inner projections 494A, 494B are no longer aligned with the slots 486A, 486B formed in the wheel member 484. In this position, when the proximal clip portions 491A, 491B of the connector member 490 are clamped, the inner projections 494A, 494B are blocked by the opposing sides of the wheel member 484, thereby preventing the proximal clip portions 491A, 491B from fully clamping to enable release of the distal clip portions 492A, 492B. Thus, in this "advanced" position of the wheel member 484, the connector member 490 and the wheel member 484 interact to substantially prevent inward movement (i.e., clamping) of the proximal clip portions 491A, 491B, thus preventing removal of the fluid transfer device 480 from the needleless access connector when the probe is in the "advanced" position.

[0101] 34 and 35, a fluid transfer device 500 according to another aspect of the present disclosure is illustrated. The fluid transfer device 500 includes a housing 502 and a probe advancement mechanism (not shown) including, for example, a wheel member, a linear advancement member, etc. The probe advancement mechanism is configured to operatively advance and / or retract a flexible probe 504 toward and / or from a distal introducer portion 517 located at a distal end portion of the housing 502.

[0102] Also provided is a connector member 514 configured to selectively couple the fluid transfer device 500 to a needleless access connector of, for example, an adapter coupled to a vascular access device (not shown). The connector member 514 is configured as an alligator clip style connector with opposing distal clip portions 516A, 516B allowing the fluid transfer device 500 to be secured to a surface of the needleless access connector and a pair of proximal clip portions 515A, 515B sized and configured to be clamped or otherwise manipulated by a user to release the connector member 514 from engagement with the needleless access connector.

[0103] 2-33, which utilize interaction with a probe advancement mechanism (e.g., a wheel member) to selectively prevent disengagement of the connector members, the fluid transfer device 500 utilizes the probe 504 itself to control prevention of connector member disengagement. In particular, the probe 504 includes a protruding member 506 extending from at least one side of the probe 504 in proximity to the connector member 514. The protruding member 506 may be integrally formed as part of the probe 504 or may be a separate component coupled to the probe 504 by any suitable connection method.

[0104] The fluid transfer device 500 further includes a locking member 508 configured to move longitudinally along the housing 502, the longitudinal movement being based on the position of the probe 504. The locking member 508 includes a proximal end portion 512 and a protruding portion 510. The proximal end portion 512 is configured to provide an interface between the locking member and the protruding member 506 as the probe 504 advances from the distal introducer portion 517. Although not shown, it should be understood that the locking member 508 may be biased in a proximal direction (i.e., away from the connector member 514), for example, via a spring.

[0105] 34, when the probe 504 is in a first position such that it is retracted into the distal introducer portion 517 and housing 502, the protruding member 506 does not contact the proximal end portion 512 of the locking member 508, thereby allowing the locking member 508 to be biased toward its proximal-most position. Thus, when the proximal clip portions 515A, 515B of the connector member 514 are clamped, one or more of the proximal clip portions 515A, 515B do not contact the protruding portion 510 of the locking member 508, allowing the proximal clip portions 515A, 515B to be fully clamped and the distal clip portions 516A, 516B to be released from engagement with the needleless access connector, and therefore the fluid transfer device 500 to be removed from engagement with the needleless access connector.

[0106] 35, on the other hand, upon advancing the probe 504 towards the second position through the distal introducer portion 517, the protruding member 506 is configured to urge the locking member 508 distally such that the protruding portion 510 of the locking member 508 is aligned substantially below one or more of the proximal clip portions 515A, 515B. In this position, when the proximal clip portions 515A, 515B of the connector member 514 are clamped, the protruding portion 510 prevents the proximal clip portions 515A, 515B from being fully clamped. Thus, in this "advanced" position of the probe 504, the locking mechanism 508 acts to substantially prevent inward movement (i.e., clamping) of the proximal clip portions 515A, 515B, thus preventing removal of the fluid transfer device 500 from the needleless access connector.

[0107] 36 and 37, a fluid transfer device 520 according to another embodiment of the present disclosure is illustrated. The fluid transfer device 520 includes a housing 522 and a probe advancement mechanism (not shown) comprising, for example, a wheel member, a linear advancement member, or the like. The probe advancement mechanism is configured to operatively advance and / or retract a flexible probe 524 toward and / or from a distal introducer portion 537 located at a distal end portion of the housing 522.

[0108] Also provided is a connector member 534 configured to selectively couple the fluid transfer device 520 to a needleless access connector of, for example, an adapter coupled to a vascular access device (not shown). The connector member 534 is configured as an alligator clip style connector with opposing distal clip portions 536A, 536B allowing the fluid transfer device 520 to be secured to a surface of the needleless access connector and a pair of proximal clip portions 535A, 535B sized and configured to be clamped or otherwise manipulated by a user to release the connector member 534 from engagement with the needleless access connector.

[0109] 34 and 35, the fluid transfer device 520 utilizes the probe 524 itself to control prevention of disengagement of the connector member 534. In particular, the probe 524 includes a protruding member 526 extending from at least one side of the probe 524 proximate the connector member 534. The protruding member 526 may be integrally formed as part of the probe 524 or may be a separate component coupled to the probe 524 by any suitable connection method.

[0110] The fluid transfer device 520 further includes a locking member 528 configured to move laterally relative to the housing 522, substantially transverse to the direction of the probe 524. The lateral movement of the locking member 528 is based on the position of the probe 524, and the locking member 528 can be biased radially outwardly by a biasing member 530 (e.g., a spring). The biasing member 530 may be offset to avoid interference with the probe 524 within the housing 522.

[0111] 36, when the probe 524 is in a first position retracted into the distal introducer portion 537 and the housing 522, the protrusion member 526 does not contact any portion of the locking member 528, nor does the protrusion member 526 contact the retaining member 532 associated with the locking member 528. Thus, when the proximal clip portions 535A, 535B of the connector member 534 are clamped together, the retaining member 532 acts to hold the locking member 528 and the biasing member 530 in a compressed position within the housing 522, such that one or more of the proximal clip portions 535A, 535B do not come into contact with the locking member 528. This position of the locking member 528 allows the proximal clip portions 535A, 535B to be fully clamped, releasing the distal clip portions 536A, 536B from engagement with the needleless access connector, and thus allowing the fluid transfer device 520 to be removed from engagement with the needleless access connector.

[0112] 37, upon advancing the probe 524 towards the second position and through the distal introducer portion 537, the protrusion member 526 is configured to urge the retaining member 532 distally, thereby releasing the locking member 528 from engagement with the retaining member 532 and the biasing member 530 biases the locking member 528 radially outwardly to align at least a portion of the locking member 528 substantially beneath one or more of the proximal clip portions 535A, 535B. In this position, when the proximal clip portions 535A, 535B of the connector member 534 are clamped, the locking member 528 prevents one or both of the proximal clip portions 535A, 535B from being fully clamped, thereby preventing removal of the fluid transfer device 520 from the needleless access connector.

[0113] 38 and 39, a fluid transfer device 540 according to another aspect of the present disclosure is illustrated. The fluid transfer device 540 includes a housing 542 and a probe advancement mechanism 544 including, for example, a wheel member. The probe advancement mechanism 544 is configured to operatively advance and / or retract a flexible probe (not shown) between a distal introducer portion 554 located at a distal end portion of the housing 542. Also provided is a connector member 550 configured to selectively couple the fluid transfer device 540 to, for example, a needleless access connector of an adapter coupled to a vascular access device (not shown). The connector member 550 is configured as an alligator clip type connector, with opposing distal clip portions 552A, 552B enabling the fluid transfer device 540 to be secured to a surface of the needleless access connector, and a pair of proximal clip portions 551A, 551B sized and configured to release the connector member 550 from engagement with the needleless access connector by being clamped or otherwise manipulated by a user.

[0114] The fluid transfer device further includes a locking member 548 disposed on the housing 542 adjacent the connector member 550, the locking member 548 being slidable longitudinally along the housing 542. The locking member 548 can include a proximal button portion 546 configured, for example, as an interface for a user's thumb or finger. The locking member 548 can also include a distal blocking portion 549 extending therefrom.

[0115] The locking member 548 may be biased to a predetermined position to position the distal blocking portion 549 beneath one or both of the proximal clip portions 551A, 551B, thereby preventing actuation (i.e., pinching) of the proximal clip portions 551A, 551B upon insertion of the fluid transfer device 540. Only after the user manually retracts the locking member 548 by pulling the proximal button portion 546 in a proximal direction does the distal blocking portion 549 move away from the connector member 550, thereby allowing the proximal clip portions 551A, 551B to release the connector member 550 from engagement with the needleless access connector as a result of pinching or otherwise being manipulated by the user.

[0116] As shown in FIG. 39, in some embodiments, the proximal button portion 546 (and / or other portions of the locking member 548) may include written instructions or other visual indicators to remind the user that the probe must be retracted (e.g., via rotation of the probe advancement mechanism 544) prior to disengaging the locking member 548 and retracting the fluid transfer device 540 from the needleless access connector.

[0117] 40, there is shown a fluid transfer device 560 according to another aspect of the present disclosure. The fluid transfer device 560 includes a housing 562 and a wheel member 564. The wheel member 564 is configured to operatively advance and / or retract a flexible probe (not shown) between a distal introducer portion 574 located at a distal end portion of the housing 562.

[0118] Also provided is a connector member 570 configured to selectively couple the fluid transfer device 560 to a needleless access connector of, for example, an adapter coupled to a vascular access device (not shown). The connector member 570 is configured as an alligator clip style connector with opposing distal clip portions 572A, 572B allowing the fluid transfer device 560 to be secured to a surface of the needleless access connector and a pair of proximal clip portions 571A, 571B sized and configured to be clamped or otherwise manipulated by a user to release the connector member 570 from engagement with the needleless access connector.

[0119] The fluid transfer device further includes a slide lock member 568 disposed on or within the housing 562 adjacent the connector member 570, the slide lock member 568 being slidable longitudinally along a portion of the housing 562. The slide lock member 568 can include at least one protrusion 569 configured, for example, as an interface for a user's thumb or finger. The slide lock member 568 can also include an arm member 566 extending proximally therefrom.

[0120] The wheel member 564 includes a slot 565 sized and configured to selectively receive at least a portion of the arm member 566 therein. A portion of the arm member 566 can be aligned and received within the slot 565 only when the wheel member 564 is rotated to retract the probe into the distal introducer portion 574 and the housing 562. Thus, when the arm member 566 and the slot 565 are aligned, the user can manually retract the sliding lock member 568 proximally, thereby pinching the pair of proximal clip portions 571A, 571B to disengage the connector member 570 from the needleless access connector. With the arm member 566 at least partially within the slot 565 in this position, the wheel member 564 is prevented from rotating, thereby preventing the advancement or retraction of the probe when the connector member 570 is disengageable.

[0121] However, if the user wishes to advance or retract the probe via rotation of the wheel member 564, the user must move the sliding lock member 568 distally to disengage the arm member 566 from the slot 565. This distal movement of the sliding lock member 568 also causes the distal "ring" portion of the sliding lock member 568 to move substantially below one or more of the proximal clip portions 571A, 571B, thereby preventing actuation of the connector member 570 and removal of the fluid transfer device 560 from the needleless access connector while the wheel member 564 is capable of rotation and thus the probe is capable of being advanced beyond the distal introducer portion 574.

[0122] 41, a fluid transfer device 580 according to another embodiment of the present disclosure is shown. The fluid transfer device 580 includes a housing 582 and a wheel member 584 configured to operatively advance and / or retract a flexible probe (not shown) between a distal introducer portion (not shown) located at a distal end portion of the housing 582. Also provided is a connector member 590 configured to selectively couple the fluid transfer device 580 to a needleless access connector 594 of, for example, an adapter coupled to a vascular access device (not shown). The connector member 590 is configured as an alligator clip type connector, with opposing distal clip portions 592A, 592B allowing the fluid transfer device 580 to be secured to a surface of the needleless access connector 594, and a pair of proximal clip portions 591A, 591B sized and configured to release the connector member 590 from engagement with the needleless access connector by pinching or otherwise manipulating the connector member 590 by a user.

[0123] Fluid transfer device 580 further includes a locking member 586 disposed on or partially within housing 582 between connector member 590 and wheel member 584, where locking member 586 is configured to be slidable longitudinally along housing 582. Locking member 586 can include a proximal button portion 587 configured, for example, as an interface for a user's thumb or finger, and a distal blocking portion 588 extending therefrom.

[0124] 41, the wheel member 584 may include a slot or other interface that is interlockable with a portion of the locking member 586. That is, a portion of the locking member 586 may be aligned and receivable within an interlocking interface with the wheel member 584 only when the wheel member 584 is rotated such that the probe is retracted into the distal introducer portion and housing 582. Thus, upon proximal retraction of the locking member 586 such that an interlock exists between the locking member 586 and the wheel member 584, the distal blocking portion 588 of the locking member 586 may be moved proximally away from the connector member 590, thereby pinching the pair of proximal clip portions 591A, 591B to release the connector member 590 from engagement with the needleless access connector 594. Additionally, the interlock between the locking member 586 and the wheel member 584 prevents rotation of the wheel member 584, thereby preventing advancement or retraction of the probe when the connector member 590 is removable from the needleless access connector 594.

[0125] Conversely, if a user wishes to advance or retract the probe by rotation of the wheel member 584, the user must move the locking member 586 distally to release the interlock between the locking member 586 and the wheel member 584. This distal movement of the locking member 586 also moves the at least one protruding portion 588 substantially below one or more of the proximal clip portions 591A, 591B, thereby preventing actuation of the connector member 590 and removal of the fluid transfer device 580 from the needleless access connector while the wheel member 584 is rotatable and thus the probe is advanceable beyond the distal introducer portion.

[0126] Although not shown in FIG. 41 , it should be appreciated that in some embodiments, the proximal button portion 587 (and / or other portions of the locking member 586) may include written instructions or other visual indicators to remind the user that the probe must be retracted (e.g., via rotation of the probe advancement mechanism 584) prior to disengaging the locking member 586 and removing the fluid transfer device 580 from engagement with the needleless access connector.

[0127] All examples and conditional statements incorporated herein are intended for educational purposes to aid the reader in understanding the concepts contributed by the inventor to further develop the present invention and the art, and are not to be construed as being limited to those specifically incorporated examples and conditions. Although the embodiments of the present invention have been described in detail, it should be understood that various changes, substitutions, and alterations can be made herein without departing from the spirit and scope of the present invention.

Claims

1. 1. A fluid transfer device for delivering a probe to a patient's vascular system, the fluid transfer device comprising: Housing; a distal introducer portion disposed at a distal end portion of the housing and configured to penetrate a needleless access connector of a vascular access device; a wheel member rotatable relative to the housing, the wheel member operably coupled to the probe to advance and retract the probe through the distal introducer portion based on a direction of rotation of the wheel member; a connector member disposed adjacent the distal introducer portion and configured to releasably connect to at least one surface of the needleless access connector, the connector member including a pair of opposing distal clip portions and a pair of opposing proximal clip portions; a locking member operably coupled to the wheel member and configured to prevent actuation of at least one of the pair of opposing proximal clip portions when the wheel member is rotated to a first position and to allow actuation of at least one of the pair of opposing proximal clip portions when the wheel member is rotated to a second position; A fluid transfer device comprising:

2. 2. The fluid transfer device of claim 1, wherein the wheel member includes a clocking member, and the locking member is operatively connected to the clocking member.

3. 3. The fluid transfer device of claim 2, wherein the locking member includes an arm connected to the clocking member.

4. 4. The fluid transfer device of claim 3, wherein one end of the arm includes a post configured to ride within a cam groove formed in the clocking member.

5. 2. The fluid transfer device of claim 1, wherein the locking member comprises a ring member longitudinally slidable over at least a portion of the housing.

6. 2. The fluid transfer device of claim 1, wherein the locking member includes a biasing member configured to bias the locking member in one direction.

7. 2. The fluid transfer device of claim 1, further comprising a rack member and a pinion gear, the pinion gear operably coupled to the wheel member, and the rack member coupled to the locking member to longitudinally displace the locking member based on a direction of rotation of the wheel member.

8. 10. The fluid transfer device of claim 1, wherein the locking member includes at least one tab displaceable by a wire operatively coupled to the wheel member.

9. 2. The fluid transfer device of claim 1, wherein the locking member includes at least one proximal arm member, and the wheel member includes at least one slot provided in a radial surface of the wheel member, the at least one slot having a size and configuration to accommodate at least a portion of the at least one proximal arm member.

10. 10. The fluid transfer device of claim 9, wherein the locking member further comprises at least one living hinge, the living hinge being connected at a first end to at least one of the pair of opposing proximal clip portions and at a second end to the at least one proximal arm member.

11. 10. The fluid transfer device of claim 9, wherein the locking member further comprises an angled distal member.

12. 2. The fluid transfer device of claim 1, wherein the locking member is manually displaceable by a user.

13. 13. The fluid transfer device of claim 12, wherein the locking member includes a distal blocking portion and a proximal button portion, the proximal button portion configured as a user interface.

14. 1. A fluid transfer device for needle-free delivery of a probe to a patient's vascular system, the fluid transfer device comprising: Housing; a distal introducer portion disposed at a distal end portion of the housing and configured to penetrate a needleless access connector of a vascular access device; a wheel member rotatable relative to the housing, the wheel member operably coupled to the probe to advance and retract the probe through the distal introducer portion based on a direction of rotation of the wheel member; a connector member disposed proximate the distal introducer portion and configured to releasably connect to at least one surface of the needleless access connector; a locking member that prevents disengagement of the connector member from the needleless access connector when the wheel member is rotated to a first position and allows disengagement of the connector member when the wheel member is rotated to a second position; A fluid transfer device comprising:

15. 15. The fluid transfer device of claim 14, wherein the locking member comprises a sleeve member.

16. 16. The fluid transfer device of claim 15, wherein the sleeve member is configured to extend over at least a portion of the connector member when the wheel member is rotated to the first position.

17. 15. The fluid transfer device of claim 14, wherein at least a portion of the locking member is configured to extend beneath at least a portion of the connector member when the wheel member is in the first position.

18. 15. The fluid transfer device of claim 14, wherein the wheel member further includes a pair of opposing slots on opposing sides of the wheel member, and the locking member includes a pair of opposing inward protrusions on a proximal portion of the connector member, the pair of opposing inward protrusions configured to engage with the pair of opposing slots when the wheel member is rotated to the second position.

19. 15. The fluid transfer device of claim 14, further comprising a protruding member extending from at least one side of the probe, the protruding member configured to permit movement of the locking member based on a position of the probe within the housing.

20. 15. The fluid transfer device of claim 14, wherein the locking member is manually displaceable by a user, and further wherein the locking member comprises a distal blocking portion and a proximal button portion, the proximal button portion being configured as a user interface.

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