Electrochemical detection chip

The electrochemical detection chip addresses stability and positioning issues by using a linked Ag/AgCl reference electrode and multiple support arms, ensuring stable reference potential and accurate specimen placement for improved embryo health assessment.

JP2026015311APending Publication Date: 2026-01-29CHUNG SHAN MEDICAL UNIVERSITY +1
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Patent Information

Application Number
JP2025121257
Authority / Receiving Office
JP · JP
Patent Type
Applications
Current Assignee / Owner
Priority Date
2024-07-18
Filing Date
2025-07-18
Publication Date
2026-01-29

AI Technical Summary

Technical Problem

Existing electrochemical detection chips face challenges in reference potential stability and analyte immobilization, particularly due to the proximity of working and reference electrodes, which can affect the physiological function of the analyte and cause specimen manipulation difficulties.

Method used

The electrochemical detection chip incorporates a reference material layer with a linked Ag/AgCl reference electrode in a fluidically independent reference groove, connected by a salt bridge, and a first structural layer with multiple support arms to guide the specimen, enhancing stability and positioning accuracy.

Benefits of technology

This design stabilizes the reference potential, prevents electrolyte leakage, reduces specimen manipulation difficulties, and improves detection performance by accurately positioning embryos for reliable oxygen consumption rate measurements.

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Abstract

To provide a new electrochemical detection chip used for evaluation of cell respiration activity and improved in reference potential, fixation stability of a specimen, and the like.SOLUTION: An electrochemical detection chip includes a base layer, an electrode chip, an insulation layer, a reference material layer, a first structure layer installed on the insulation layer and including a plurality of bottom part support arms whose end parts are adjacent to each other to define a specimen storage area together, a coating layer, and a salt bridge connection layer. The electrochemical detection chip of the present invention can be used to detect the respiration activity of embryos.SELECTED DRAWING: Figure 1
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Citation Information

Patent Citations

  • Manufacturing method of electrochemical measuring device

    JP2009174948A

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