External composition for skin or hair care

A skin or hair care composition with hexylresorcinol and ethyl linoleate addresses the inadequacies of existing preparations by reducing acne and pigmentation, achieving smooth and bright skin through anti-inflammatory and antibacterial actions.

JP2026019948APending Publication Date: 2026-02-05IKEDA BUSSAN CO
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Patent Information

Application Number
JP2024135143
Authority / Receiving Office
JP · JP
Patent Type
Applications
Current Assignee / Owner
Filing Date
2024-07-26
Publication Date
2026-02-05

AI Technical Summary

Technical Problem

Existing topical preparations for acne and pigmentation have not been satisfactory in preventing and improving these skin issues.

Method used

A skin or hair care composition containing a mixture of hexylresorcinol and ethyl linoleate, which provides anti-inflammatory, antibacterial, and melanin production inhibitory effects.

Benefits of technology

The composition effectively reduces acne and pigmentation, maintaining smooth and bright skin by incorporating hexylresorcinol and ethyl linoleate, with synergistic effects from additional ingredients.

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Abstract

The skin located in the outermost layer of a living body is routinely stimulated by external ultraviolet rays, bacteria, chemical substances, and the like, and when the homeostasis of the skin is disturbed, inflammation, pigmentation, and the like due to acne and the like occur. Acne is caused by proliferation of Propionibacterium acnes, and it is said that Propionibacterium acnes decomposes triglyceride in sebum, and the produced fatty acid causes inflammation. On the other hand, melanin, which is synthesized for UV protection, is excessively produced by a large amount of ultraviolet light and causes skin pigmentation. Under such circumstances, studies on ingredients for preventing and improving acne and pigmentation have been carried out and external preparations have been developed, but the effects thereof are not necessarily satisfactory SOLUTION: The present invention provides a novel external preparation composition for skin or hair care that prevents acne and pigmentation and improves the skin to a smooth and bright state by blending a mixture of hexylresorcinol and ethyl linoleate.SELECTED DRAWING: Figure 1
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Description

[Technical Field]

[0001] The present invention relates to a topical skin or hair care composition containing a mixture of hexylresorcinol and ethyl linoleate. Here, the topical skin or hair care composition refers to skin care cosmetics such as face washes, lotions, creams, and packs; makeup cosmetics such as foundations, lipsticks, and mascaras; hair care cosmetics such as shampoos, conditioners, hair styling agents, hair growth agents, hair colorants, and permanent wave agents; body care cosmetics such as body soaps, slimming agents, UV protection agents, bath agents, and antiperspirants; and fragrance cosmetics such as perfumes and colognes, including legal cosmetics, quasi-drugs, and pharmaceuticals. [Background technology]

[0002] The skin, located at the outermost layer of the body, is exposed to external stimuli such as ultraviolet rays, bacteria, and chemicals on a daily basis, and when the skin's homeostasis is disturbed, inflammation such as acne and pigmentation occur.

[0003] Acne is caused by excessive sebum secretion and abnormal keratinization, which clogs pores and causes sebum accumulation, leading to the proliferation of acne bacteria, a type of skin flora. It is said that acne bacteria break down the triglycerides in sebum, and the fatty acids they produce cause inflammation.

[0004] On the other hand, melanin, which is synthesized by melanocytes to protect against ultraviolet rays, is produced in excess when exposed to large amounts of ultraviolet rays, causing pigmentation.

[0005] To maintain smooth, bright, and ideal skin, skin care that prevents acne and pigmentation is effective.

[0006] To prevent acne, it is effective to cleanse the skin by washing the face or cleansing it, remove sebum from pores, and use topical agents with moisturizing, anti-inflammatory, antibacterial, and astringent properties. To prevent pigmentation caused by melanin production, it is useful to apply sunscreen to protect the skin from UV rays, as well as to inhibit the UV-induced melanin production pathway.

[0007] As a means of preventing acne, Patent Document 1 discloses the anti-acne effect of a natural molecule present in a plant (Artocarpus hirsutus), and Patent Document 2 discloses the melanin production inhibitory effect of a peptide consisting of a specific amino acid sequence. [Prior art documents] [Patent documents]

[0008] [Patent Document 1] Special Publication No. 2020-512394 [Patent Document 2] Japanese Patent Publication No. 2022-106946 DISCLOSURE OF THE INVENTION [Problem to be solved by the invention]

[0009] Against this background, research into ingredients that prevent and improve acne and pigmentation has progressed, and topical preparations have been developed, but the effects have not always been satisfactory. [Means for solving the problem]

[0010] The present invention has been made under the above circumstances and provides a novel skin or hair care topical composition that prevents both acne and pigmentation and improves skin to a smooth and bright state by incorporating a mixture of hexylresorcinol and ethyl linoleate.

[0011] The first aspect of the present invention is a skin or hair care composition containing a mixture of hexylresorcinol and ethyl linoleate.

[0012] Claim 2 of the present invention is the external skin or hair care composition according to claim 1, wherein the mixture of hexylresorcinol and ethyl linoleate is 0.01 to 20.0% by mass. [Effects of the Invention]

[0013] Of the mixture of hexylresorcinol and ethyl linoleate of the present invention, hexylresorcinol has anti-inflammatory, antibacterial, post-inflammatory pigmentation reduction, melanin production inhibitory effects, etc., while ethyl linoleate has anti-acne and tyrosinase protein decomposition promoting effects, etc. Due to these effects, when incorporated into an external preparation composition, acne and pigmentation are improved, and smooth and bright skin can be maintained. [Brief explanation of the drawings]

[0014] [Figure 1] Figure 1 shows the acne-improving effect of the mixture of hexylresorcinol and ethyl linoleate of the present invention. When a lotion containing 3% of the mixture of the present invention (commercially available raw materials "Synactin AC" or "Asintra SL") was applied twice a day for 3 and 6 weeks, acne was reduced and pore size was also improved. [Figure 2] Figure 2 shows the skin lightening effect of the mixture of hexylresorcinol and ethyl linoleate of the present invention. When a lotion containing 2% of the mixture of the present invention (commercially available raw materials "Synactin AC" or "Asintra SL") was applied twice daily for four weeks, it was found to improve ITA° (Individual Typology Angle), an index of skin lightness. DETAILED DESCRIPTION OF THE INVENTION

[0015] The present invention will be described in detail below. The method for producing the mixture of hexylresorcinol and ethyl linoleate used in the present invention is not particularly limited, but a solution of synthetically obtained hexylresorcinol and caprylic / capric triglyceride of plant-derived ethyl linoleate is available as a commercial raw material "Synactin AC" or "Asyntra SL" from Sytheon Ltd., USA.

[0016] The blending amount of the mixture of hexylresorcinol and ethyl linoleate of the present invention is 0.01 to 20.0% by mass, preferably 0.1 to 4.0% by mass, based on the total amount of the topical skin or hair care composition using the above-mentioned commercially available raw materials. When preparing a typical topical skin or hair care composition, if the blending amount is less than 0.01% by mass, the effects of preventing acne and pigmentation and improving skin condition will not be achieved. Although blending in amounts exceeding 4.0% by mass up to 20.0% by mass is conceivable, this is not preferred because the effects commensurate with the blending amount will gradually saturate.

[0017] The effects of the topical skin or hair care composition of the present invention include preventing the occurrence of acne and skin pigmentation, and maintaining smooth and bright skin. Therefore, further effects can be expected by combining the topical skin or hair care composition of the present invention with ingredients that have antibacterial, anti-inflammatory, keratolytic / exfoliating, or whitening effects. Examples of such ingredients include salicylic acid, allantoin, glycolic acid, vitamin C and its derivatives, arbutin, tranexamic acid, and plant extracts.

[0018] In addition to the essential ingredients described above, the topical skin or hair care composition of the present invention may contain other ingredients that are typically used in topical skin or hair care compositions, such as cosmetics and pharmaceuticals. Examples of such other ingredients include the following. The topical skin or hair care composition of the present invention is produced by blending one or more of these ingredients with the essential ingredients described above in accordance with a conventional method.

[0019] The oily components include the following: Avocado oil, apricot kernel oil, olive oil, cocoa butter, beef tallow, sesame oil, wheat germ oil, camellia oil, safflower oil, hydrogenated moringa oil, soybean oil, tea seed oil, evening primrose oil, camellia oil, glycolipids, triglyceride (C10-18) glyceryl triphosphate, peppermint leaf oil, palm kernel oil, palm oil, castor oil, sunflower seed oil, boswellia serrata oil, macadamia seed oil, manuka oil, horse fat, melia azadirachta seed oil, cottonseed oil, Japan wax, (moringa oil / hydrogenated moringa oil) esters, coconut oil, lemon fruit oil, phospholipids, horseradish perilla seed oil, etc. Waxes such as carnauba wax, candelilla wax, rice bran wax, hydrogenated jojoba oil, sunflower seed wax, acacia dealbata flower wax, partially hydrogenated jojoba oil, jojoba ester, jojoba seed oil, beeswax, and lanolin. Hydrocarbons such as isoparaffin, hydrogenated polyisobutene, squalane, squalene, ceresin, paraffin, microcrystalline wax, liquid paraffin, and petrolatum. Higher fatty acids such as isostearic acid, oleic acid, stearic acid, palmitic acid, hydroxystearic acid, behenic acid, myristic acid, lauric acid, linoleic acid, and linolenic acid. Higher alcohols such as isostearyl alcohol, 2-octyldodecanol, oleyl alcohol, cholesterol, stearyl alcohol, cetyl alcohol, cetearyl alcohol, soybean sterol, phytosterols, behenyl alcohol, jojoba alcohol, myristyl alcohol, and lanolin alcohol. Alkyl glyceryl ethers such as chimyl alcohol and batyl alcohol. Isostearyl Isostearate, Phytostearyl Isostearate, Propylene Glycol Isostearate, Cetyl 2-Ethylhexanoate, Ethoxydiglycol Behenate, Ethoxydiglycol Oleate, Hydrolyzed Jojoba Esters, Triethyl Citrate, Diethylene Glycol Monoethyl Ether, Isosorbide Dicaprylate, Glycol Distearate, Propylene Glycol Dinonanoate, Cholesteryl Stearate, Stearyl Stearate, Caprylic / Capric Triglyceride, Triheptanoate Esters such as glyceryl tri-2-hexanoate, ethylhexyl palmitate, behenyl / oleic acid esters, pentaerythritol tetraester, isopropyl jojoba oil, jojoba oil / macadamia seed oil esters, ethyl macadamiate, phytosteryl macadamiate, isopropyl myristate, octyldodecyl myristate, butylene glycol coconut oil fatty acid, propylene glycol laurate, and diisostearyl malate. Silicones such as amino-modified silicone, alkyl-modified silicone, cyclic dimethyl silicone oil, silicone rubber, methylhydrogenpolysiloxane, methylphenylpolysiloxane, and methylpolysiloxane.

[0020] Examples of polyhydric alcohols include ethoxydiglycol, octanediol, polyglycerols such as glycerin, diethylene glycol and diglycerin, dipropylene glycol, 1,3-butylene glycol, propylene glycol, hexanediol, heptanediol, pentanediol, polyethylene glycol, and the like.

[0021] Examples of sugars include xylitol, sucrose, sorbitol, trehalose, lactose, fructose, maltitol, mannitol, and rhamnose.

[0022] Examples of the polymer compound include the following: Natural polymers such as Alcaligenes polysaccharides, alginic acid, casein, curdlan, carrageenan, agar, xanthan gum, chitosan, guar gum, quince seed, collagen, sclerotium gum, gelatin, dextrin, starch, hyaluronic acid, pullulan, pectin, and mannan. Natural polymer derivatives such as acetylated hyaluronic acid, ethyl cellulose, cationized guar gum, cationized cellulose, carboxymethyl cellulose, stearoxyhydroxypropyl methylcellulose, nitrocellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, hydroxypropyl methylcellulose, polyquaternium-10, polyquaternium-67, and methyl cellulose. Synthetic polymers such as POE-POP copolymer, alkyl acrylate copolymer, acrylic acid-acrylic acid amide-ethyl acrylate copolymer, acrylic resin alkanolamine, alkyl acrylate-vinyl acetate copolymer, acrylates copolymer Na, carboxyvinyl polymer, highly polymerized polyethylene glycol, polymeric silicone, silicone resin, (styrene / acrylates) copolymer, vinyl methyl ether-ethyl maleate copolymer, polyacrylic acid amide, polyacrylic acid sodium, polydimethylpiperidinium chloride, polyoxypropylene butyl ether, polyvinyl acetate, polyvinyl alcohol, and polyvinylpyrrolidone.

[0023] The surfactants include the following: Anionic surfactants such as acyl N-methyl taurine salts, POE alkyl ether carboxylates, POE alkyl ether sulfates, alkyl ether phosphate ester salts, alkylbenzenesulfonates, alkyl sulfate ester salts, N-acyl amino acid salts, α-olefin sulfonates, higher fatty acid soaps, sodium stearoyl glutamate, and sodium stearoyl lactylate. Cationic surfactants such as alkyltrimethylammonium chloride, dialkyldimethylammonium chloride, and benzalkonium chloride. Amphoteric surfactants such as alkylamidopropyldimethylaminoacetic acid betaine, alkylamidobetaine, 2-alkyl-N-carboxymethyl-N-hydroxyethylimidazolinium betaine, alkyldimethylaminoacetic acid betaine, hydrogenated lecithin, lysolecithin, and lecithin. POE Alkylamine / Fatty Acid Amide, POE Alkyl Ether, POE / POP Alkyl Ether Alkylamine Oxide, Alkyl Glucoside, PEG-6 Isostearate, Polyglyceryl-6 Isostearate, Ethoxydiglycol, PEG-8 Caprylic / Capric Glycerides, (Candelilla / Jojoba / Rice Bran) Polyglyceryl-3 Esters, Glycerin Fatty Acid Esters, POE Glycerin Fatty Acid Esters, Polyglyceryl-3 Diisostearate, Polyglyceryl-3 Dioleate, Polyglyceryl-6 Distearate, Fatty Acid Alkanolamides, PEG Fatty Acid Esters, PEG-40 Hydrogenated Castor Oil, Hydrogenated Sunflower Seed Oil Glyceryl Esters, Hydrogenated Sunflower Seed Oil Polyglyceryl-3 Esters, PEG-6 Stearate, PEG-32 Stearate, PEG Stearate Nonionic surfactants such as -75, glyceryl stearate, polyglyceryl-6 stearate, polyglyceryl-10 stearate, steareth-20, ceteth-20, sorbitan fatty acid esters, POE sorbitan fatty acid esters, POE sorbitan fatty acid esters, triisostearin PEG-6 esters, tribehenin PEG-20 esters, POE castor oil / hydrogenated castor oil, PEG-10 sunflower glycerides, glyceryl behenate, jojoba wax PEG-80 esters, jojoba wax PEG-120 esters, jojoba oil PEG-150 esters, polyoxyethylene beeswax, polyglyceryl-3 beeswax, polysorbate 80, polyglyceryl-6 polyhydroxystearate, polyglyceryl-6 polyricinoleate, PEG-16 macadamia glycerides, and PEG-8 beeswax.

[0024] Examples of coloring materials, powders, and particles include the following. Coloring materials such as inorganic pigments such as yellow iron oxide, carbon black, black iron oxide, red iron oxide, and ultramarine, pearl pigments, organic pigments, tar dyes, and natural dyes. Inorganic powders such as zinc oxide, alumina, (alumina / iron oxide / titanium oxide / mica) complex, (alumina / titanium oxide / sodium silicate / silica) complex, (alumina / titanium oxide / silica) complex, (alumina / titanium oxide / silica / dimethicone) complex, (alumina / silica) complex, (alumina / silica / talc) complex, mica, titanium mica, kaolin, magnesium aluminum silicate, titanium oxide, (titanium oxide / zirconium oxide / silica) complex, (titanium oxide / silica) complex, (titanium oxide / talc) complex, iron oxide, (iron oxide / titanium oxide / silica / mica) complex, (iron oxide / titanium oxide / mica) complex, (iron oxide / silica) complex, (iron oxide / silica / dimethicone) complex, silica, (silica / polyurethane-15 / mica) complex, (silica / mica) complex, zeolite, talc, hectorite, bentonite, mica, (mica / polyurethane-15) complex, and magnesium sodium silicate. Organic powders such as silk powder, cellulose powder, nylon powder, and polyethylene powder. Granules of fatty acid esters, cellulose, natural products, nylon, polyethylene, wax, etc.

[0025] Ingredients of natural origin include the following: Elastin, hydrolyzed casein, hydrolyzed keratin, hydrolyzed collagen, hydrolyzed silk, hydrolyzed soy protein, hydrolyzed pearl, chitin, chitosan, collagen, sodium chondroitin sulfate, water-soluble collagen, lactose, sodium hyaluronate, whey protein, peptides, and other substances of animal and microbial origin. Acacia Victoria Fruit Extract, Acacia Victoria Seed Extract, Actinidia Deliciosa Fruit Extract, Acronitia Acidula Fruit Extract, Asparagopsis Armata Extract, Acerola Fruit Extract, Anigozanthus Mangresi Flower Extract, Anigozanthus Flavidus Flower / Leaf Extract, Anetrea Anisata Leaf Extract, Alaria Esculenta Extract, Arctium Majus Root Extract, Arnica Montana Flower Extract, Aloe Ferox Leaf Extract, Aloe Vera Leaf Extract, Italian Cypress Leaf / Fruit / Stem Oil, Strawberry Fruit Extract, Ginkgo Biloba Leaf Extract, Iris Root Extract, Witha Nia somnifera root extract, Urtica dioica extract, Uva-ursi leaf extract, Ecklonia radiata extract, Rubus rubra fruit extract, Barley bark extract, Oriental thistle flower / leaf / stem extract, Barley seed extract, Panax ginseng root extract, Lamium extract, Amaranth flower extract, Orange fruit extract, Orange fruit water, Chamomile flower extract, Chamomilla recutita (matricaria) extract, Hydrolyzed wheat protein, Hydrolyzed soy protein, Oat kernel extract, Guarana seed extract, Carrot extract, Beta-carotene, Licorice root extract, Rubus idaeus extract, Rubus idaeus fruit Fruit extract, kiwi fruit extract, kiwi fruit water, Kigelia africana fruit extract, Yellow Amaranth extract, Caviar lime extract, Cucumber fruit extract, Leptospermum officinalis branch / leaf extract, Quillaja bark extract, Guava fruit extract, Wolfberry fruit extract, Sophora flavescens root extract, Cranberry fruit water, Grevillea speciosa flower extract, Grapefruit fruit water, Kunzea pomifera fruit extract, Caper fruit extract, Coconut water, Yeast extract, Rice bran water, Viola tricolor extract, Zanthoxylum piperitum seed extract, Santalum acuminatum fruit extract, Lithospermum root extract Ingredients: Syzygium reumanii fruit extract, Citrus glauca fruit extract, Ginger water, Birch extract, Horsetail extract, Japanese cedar bud extract, Black cherry fruit water, Spirulina platensis extract, Ivy leaf / stem extract, Horse chestnut seed extract, Ash bark extract, Sambucus nigra flower extract, Yarrow extract, Peppermint extract, Sage leaf extract, Mallow flower / leaf / stem extract, Rosa centifolia flower extract, Jasminum officinale flower / leaf extract, Tasmannia lanceolata fruit extract, Tasmannia lanceolata fruit / leaf extract,Davidsonia pruriens fruit extract, dulse extract, tea leaf extract, passionflower flower extract, centella asiatica extract, tea tree leaf extract, tea tree leaf oil, terminalia ferdinandiana fruit extract, angelica extract, calendula officinalis flower extract, carrot extract, tomato fruit / leaf / stem extract, kaede root extract, carrot root extract, garlic root extract, pineapple fruit extract, hibiscus flower extract, bakuchiol, bakuhousia anisa Leaf extract, Backhousia citriodora leaf extract, Lotus root water, Lotus flower extract, Papaya fruit extract, Hamamelis virginiana extract, Hamamelis virginiana bark / leaf / branch extract, Chayote fruit extract, Banksia serrata flower extract, Bambusa arundinacea stem, Daisy flower extract, Hinokitiol, Fucus extract, Hippophae rhamnoides extract, Himantaria elongata extract, Loquat leaf extract, Grape fruit water, Grape leaf extract, Beech tree seedling extract, Plumeria flower extract , Pleioginium timolense fruit extract, Luffa extract, Safflower extract, Cucurbita pepo fruit extract, Persian Walnut seed extract, Henna flower / fruit / leaf extract, Podocarpus elatus fruit extract, Madake extract, Mangifera indica fruit extract, Microcitrus australasica fruit extract, Microcitrus austris fruit extract, Mimosa tenuiflora bark extract, Pufferfish bamboo shoot water, Peach leaf extract, Cornflower flower extract, Vegetable oil, Willow herb flower Plant-based ingredients such as: / leaf / stem extract, eucalyptus extract, European birch bark extract, European beech bud extract, Ranunculus ficaria extract, Laventula hybrida oil, Labdanum oil, lavender flower / leaf / stem extract, apple fruit extract, apple fruit water, Rumex occidentalis extract, lemon fruit extract, lemon fruit water, lemon myrtle leaf, rose water, rosemary leaf extract, lowbush blueberry fruit extract, wine extract, etc. Mineral origins such as extracts of olivine, malachite, hematite, smithsonite, rhodochrosite, etc.

[0026] Examples of disinfectants and preservatives include: Benzoic acid and its salts, benzalkonium chloride, isopropylmethylphenol, chlorhexidine, salicylic acid and its salts, zinc pyrithione, sorbic acid and its salts, dehydroacetic acid and its salts, triclosan, 4-terpineol, trichlorocarbanilide, parahydroxybenzoic acid esters (methylparaben, ethylparaben, butylparaben, etc.), piroctone olamine, phenoxyethanol, hexachlorophene, hexylresorcinol, methylisothiazolinone, methylchloroisothiazolinone, etc.

[0027] Antioxidants include the following: Sodium bisulfite, vitamin C and its derivatives, vitamin E (tocopherols), butylhydroxyanisole, butylhydroxytoluene, gallic acid esters, etc. Antioxidant aids such as ascorbic acid, citric acid, cephalin, succinic acid, phytic acid, malonic acid, maleic acid, phosphoric acid, etc.

[0028] Examples of sequestering agents include: edetate, citrate, hydroxyethanediphosphonate, phytic acid, malate, etc.

[0029] Examples of UV protection agents include the following: Examples of suitable antiperspirants include urocanic acid, ethylhexyl triazone, octocrylene, ethylhexyl salicylate, diethylaminohydroxybenzoylhexyl benzoate, para-aminobenzoic acid, octyl paradimethylaminobenzoate, bisethylhexyloxyphenol methoxyphenyl triazine, 2-hydroxy-4-methoxybenzophenone, 2-hydroxy-4-methoxybenzophenone-5-sulfonic acid, phenylbenzimidazole sulfonic acid, t-butyl methoxydibenzoylmethane, homosalate, polysilicone-15, methylenebisbenzotriazolyltetramethylbutylphenol, ethylhexyl methoxycinnamate, and 2-methylphenyl 4-methoxycinnamate.

[0030] Examples of pH adjusters include the following: Organic and inorganic alkaline agents such as aminomethylpropanol, aminomethylpropanediol, ammonia water, potassium hydroxide, sodium hydroxide, sodium carbonate, triethanolamine, tromethamine, monoethanolamine, and arginine. Organic and inorganic acids such as citric acid, lactic acid, phosphoric acid, malic acid, and HCl.

[0031] The various physiologically active ingredients include the following: To prevent rough skin, it contains polyhydric alcohols such as glycerin and POE methyl glucoside, and sugars such as trehalose and pullulan. Biopolymers such as elastin, chitin / chitosan, sodium chondroitin sulfate, and sodium hyaluronate. Moisturizers such as amino acids, sodium lactate, urea, betaine, and PCA-Na. Lipid components such as cholesterol, sphingolipids, ceramides, and phospholipids. Anti-inflammatory agents such as ε-aminocaproic acid, allantoin, lysozyme chloride, guaiazulene, glycyrrhizinic acid derivatives, β-glycyrrhetinic acid, and hydrocortisone. Other ingredients include allantoin and antihistamines. Various UV protection agents for anti-aging purposes. Antioxidants such as acetylcysteine, acetylzingerone, oxothiazolidine, ethylbisiminomethylguaiacol manganese chloride, caffeic acid derivatives, carotenoids, glutathione, tannins, vitamins (B2, C, E), hydroxyethylmethylthiopropenamide, flavonoids, ubiquinone, lignans, and lycopene. Cell activators such as alpha-hydroxy acids. Blood flow promoters such as gamma-oryzanol and vitamin E and its derivatives. For the purpose of whitening, derivatives of vitamin C, sodium ascorbate, magnesium ascorbyl phosphate, ascorbic acid glucoside, etc. Melanin inhibitors such as arbutin, ellagic acid, kojic acid, linoleic acid, linolenic acid, lactic acid, tranexamic acid, etc. Other ingredients include aminoethylphosphinic acids, sulfur, glutathione, placenta extract, etc. Alpha-hydroxy acids such as citric acid, glycolic acid, tartaric acid, lactic acid, and malic acid, and retinoids (vitamin A derivatives) for the purpose of preventing wrinkles. For hair growth, vasodilators such as capronium chloride and nicotinic acid benzyl ester, local stimulants such as capsicum tincture and ginger tincture, female hormones such as estradiol and ethinylestradiol, and sebum secretion inhibitors such as pyridoxine hydrochloride. Climbazole, zinc pyrithione, piroctone olamine, etc. are used to prevent dandruff and itching. For the purpose of preventing acne, keratolytic and exfoliating agents such as sulfur, salicylic acid, and resorcinol, and disinfectants such as benzalkonium chloride and halocarban. Antiperspirants such as aluminum chloride, aluminum chlorohydrate, and zinc oxide are used to prevent underarm odor. For the purpose of various other physiological activities, vitamins such as pantothenic acid, pantethine, vitamin A and its derivatives, nicotinamide, vitamin B2 and its derivatives, vitamin B6 hydrochloride, vitamin B6 dioctanoate, vitamin B6 tripalmitate, vitamin B12, vitamin B15 and its derivatives, vitamin C such as ascorbic acid, ascorbic acid dipalmitate, ascorbic acid phosphate ester (salt), vitamin D, vitamin E such as α-tocopherol, β-tocopherol, γ-tocopherol, vitamin E acetate, vitamin E nicotinate, and vitamin H are also included. Amino acids and their derivatives, such as asparagine, aspartic acid, acetylcitrullamidoarginine, alanine, arginine, carboxyethylaminobutyric acid, glycine, glutamylamidoethylimidazole, glutamylamidoethylindole, glutamine, serine, taurine, tyrosine, decarboxycarnosine HCl, threonine, valine, histidine, hydroxyproline, pyroglutamylamidoethylindole, phenylalanine, prolinamidoethylindole, methylpropylamidoacetylmethionine, and leucine. Protein-related substances, such as acetyl tetrapeptide-2, acetyl hexapeptide-1, trifluoroacetyl tripeptide-2, tripeptide-1, nanopeptide-1, and palmitoylpeptide-1. Silanol derivatives such as ascorbyl methylsilanol pectin, aspartic acid methylsilanol hydroxyproline, alginic acid siloxanetriol, glutamic acid silanediol, salicylic acid silanediol, dioleyl tocopheryl methylsilanol, dimethyl oxobenzodioxasilane, silanetriol, silanetriol alginate, silanetriol trehalose ether, hyaluronic acid dimethylsilanol, polysilicone-3, methylsilanol acetyl tyrosine, methylsilanol sodium lactate, mannuronate acefylline methylsilanol, mannuronate methylsilanol, lysine silanetriol, PCA copper methylsilanol, and slimming-related ingredients such as caffeine and dulse extract.

[0032] The formulation of the topical skin or hair care composition of the present invention may be in the form of a liquid, emulsion, cream, gel, mist, aerosol foam, solid, powder dispersion, or the like, which is typically used as a topical skin or hair care composition. [Example]

[0033] The present invention will now be described in more detail with reference to examples. However, the present invention is not limited to these examples. The blending amounts are expressed in mass % unless otherwise specified.

[0034] Example 1 Table 1 illustrates an example of an anti-acne cream formulation. [Table 1]

[0035] Example 2 Table 2 shows an example of a skin care cream (W / O) formulation. [Table 2]

[0036] Example 3 Table 3 shows an example of the formulation of an oil beauty serum. [Table 3]

[0037] Example 4 Table 4 illustrates a facial cream formulation. [Table 4]

[0038] Example 5 Table 5 illustrates a skin care gel formulation. [Table 5]

[0039] Example 6 Table 6 shows an example of a hair cream formulation. [Table 6] [Industrial Applicability]

[0040] The present invention can be widely used in the industries of producing and selling external preparation compositions such as cosmetics, quasi-drugs, and pharmaceuticals.

Claims

1. A topical skin or hair care composition comprising a mixture of hexylresorcinol and ethyl linoleate.

2. 2. The external skin or hair care composition according to claim 1, wherein the mixture of hexylresorcinol and ethyl linoleate is present in an amount of 0.01 to 20.0% by mass.

Citation Information

Patent Citations

  • Natural molecules from Artocarpus hirsutus, their isolation methods and their anti-acne potential

    JP2020512394A

  • Peptides with skin whitening activity and their uses

    JP2022106946A