Clean room system

Abstract

To provide a clean room system.SOLUTION: The clean room system comprises a plurality of clean room modules, a plurality of docking windows and an automated guided vehicle. Each clean room module includes a plurality of dividers for quick assembly to form an interior space and an exterior area. The docking windows are respectively disposed on one of the partition plates of each clean room module, and each docking window is used as a passage of the corresponding internal space and external area. The automated guided vehicle travels in the external area. The automated guided vehicle is configured to transport an item through a passage corresponding to the docking window. Compared with the prior art, the clean room system of the present invention can be applied to a cell factory, and can also quickly and flexibly allocate production lines and traffic lines based on the schedule of the cell factory, thereby improving the production efficiency of the cell factory.SELECTED DRAWING: Figure 1

Description

[Technical Field]

[0001] The present invention relates to clean room systems, particularly those that can be quickly assembled or disassembled, and Contract development and manufacturing service format This refers to a clean room system that can be applied to cell factory manufacturing by Contract Development and Manufacturing Organization (CDMO). [Background technology]

[0002] In recent years, with the continuous advances in biotechnology and medical engineering, the demand for cell therapy in clinical applications has increased significantly. In particular, in the field of regenerative medicine, it has become possible to treat previously intractable diseases such as diabetes, neurological disorders, cardiovascular diseases, and cancer, providing patients with more treatment options. Furthermore, with the development and maturation of cell therapy products, the market is placing greater demands on large-scale, standardized cell production, and the demand for cell factories is also increasing day by day.

[0003] However, the active ingredient in cell products is the effect of live cells. Therefore, the cell pharmaceutical industry must address the specifics and unique characteristics of each cell product. For example, the growth of live cells is affected by many factors, including the cell source, culture reagents, culture environment, culture steps, personnel skills, and the complexity of the manufacturing process. Furthermore, because the cell culture process methods, appropriate environmental conditions, and parameters are not all the same, cell manufacturing factories cannot produce all cell products using the same process; laboratories must be re-planned according to the cell characteristics. Furthermore, cell culture operations require a large number of manual laboratories. However, the cell manufacturing process often involves human and subjective judgments (e.g., differences in cell density assessments due to the lack of a unified standard) and operator-to-operator errors (e.g., different operating techniques and habits of each operator), which increase uncertainty in the production process and further affect product stability and production efficiency.

[0004] Furthermore, currently, conventional cell product manufacturing processes require the transportation of raw materials and waste materials, and if the raw materials and waste materials cannot be effectively separated during transportation, there is a risk of cross-contamination, which may further affect product quality and increase the difficulty of factory quality control.

[0005] In addition, all conventional cell product manufacturing equipment on the market faces the problem of periodic downtime. When equipment in a certain area needs to be shut down or repaired, it often affects the production schedule of the entire factory, causing the entire production line to stall, increasing time costs and operational burdens. Style In this case, the suspended operation lacks flexibility, and as a result, it is not possible to adjust in real time according to different orders and equipment status, which affects production delivery dates.

[0006] Therefore, it is necessary to provide a clean room system that can quickly and flexibly adjust the factory schedule allocation according to the demand of the production line, and at the same time solve the production problems caused by cross-infection of raw materials and contaminants and equipment downtime. Summary of the Invention [Means for solving the problem]

[0007] In view of this, the present invention provides a clean room system including a plurality of clean room modules, a plurality of docking windows, and an automated guided vehicle. Quickly assembled Forming the interior space and exterior area Ruta The clean room is equipped with a plurality of partitions for transporting goods. A docking window is installed on one of the partitions of each clean room module, and each docking window is used as a passageway between the corresponding internal space and the external area. An automated guided vehicle travels in the external area. The automated guided vehicle transports goods through the passageway corresponding to the docking window.

[0008] Here, the clean room system is applied to the cell factory. Contract development and manufacturing service format This is a cell factory of a CDMO (Chemical Manufacturing Organization), and each partition is a movable partition, and the internal space of each clean room module is an airtight space. By maintaining positive pressure and laminar flow in the airtight space, the internal space of the clean room module can reach the specified cleanliness class.

[0009] Here, the clean room system further includes a main gas electrotransport device and a plurality of cell incubators. The cell incubators are installed in clean room modules among the clean room modules, and the main gas electrotransport device is installed on any of the movable partition plates among the movable partition plates of the clean room modules. The main gas electrotransport device is connected to the clean room modules and the cell incubators.

[0010] Here, the main gas electrotransport device further comprises a gas piping unit and an electrical wiring unit, and the cell culture vessels form a unified supply source for each cell culture vessel through the main gas electrotransport device.

[0011] Here, each docking window further includes a first docking window and a second docking window. Preparation The articles further include a first article and a second article, the automated guided vehicle is for transporting the first article to the interior space through the first docking window and the second article to the exterior space through the second docking window, and further, the geometric shape of the first docking window is different from the geometric shape of the second docking window.

[0012] Here, each clean room module further comprises a manipulator, the manipulator comprising a first chuck and a second chuck, the first chuck for clamping a first item and the second chuck for clamping a second item.

[0013] Here, the manipulator is for recognizing and positioning the first item, the second item, the first docking window, the second docking window, and the cell culture vessel using AI vision.

[0014] Here, the manipulator further includes a gravity sensor unit for distinguishing between the first article and the second article.

[0015] Here, the first item is raw material and the second item is waste.

[0016] Here, when the cell factory assigns a shutdown or production schedule, the clean room modules match a particular one of the clean room modules to the shutdown or production schedule by quickly removing the movable partition based on the shutdown or production schedule. [Effects of the Invention]

[0017] As described above, the present invention provides a cleanroom system whose cleanroom modules can be quickly and flexibly assembled or disassembled to suit the production line configuration based on the schedule of a CDMO cell factory. Furthermore, the present invention distinguishes between docking windows depending on the transported items. For example, raw materials are delivered only through specific automated guided vehicles and corresponding geometric windows. This effectively avoids the risk of cross-contamination between raw materials and waste. Furthermore, each cleanroom module in the cleanroom system of the present invention is independent and isolated. Therefore, when the cleanroom system of the present invention is applied to a CDMO cell factory, even if equipment in the cell factory needs to be shut down, it can be shut down independently or sequentially based on the shutdown cycle of the equipment within each cleanroom module. Furthermore, the flow paths of each cleanroom and automated guided vehicle within the cell factory can be re-adjusted based on the current schedule. Compared to prior art, the cleanroom system provided by the present invention effectively solves the problem of the entire production line stalling due to shutdowns. In addition, the modules of each clean room module can be flexibly adjusted based on the production line plan, which can effectively improve the production capacity of the entire cell factory.

[0018] Each clean room module in the clean room system of the present invention further includes a manipulator. By combining the manipulator with AI vision recognition, the accuracy of raw material transportation can be reconfirmed. The manipulator in the clean room module can also perform precise cell culture operations on the cell culture vessels inside. Compared with prior art, the clean room system of the present invention can improve production capacity and stabilize the production yield of the cell factory. In addition, the clean room system of the present invention can also install a main gas electrotransport device in a specific clean room module, connecting each cell culture vessel in the clean room module through the main gas electrotransport device to form a unified supply system. This reduces the complex verification requirements after replacing the cell culture vessel, thereby improving work and production efficiency. [Brief explanation of the drawings]

[0019] [Figure 1] 1 is a schematic diagram showing a clean room system according to a specific embodiment of the present invention; [Figure 2] FIG. 2 is a schematic diagram showing a docking window in a specific embodiment of the present invention. [Figure 3A] FIG. 1 is a schematic diagram showing a clean room system according to another specific embodiment of the present invention. [Figure 3B] FIG. 1 is a schematic diagram showing a clean room system according to another specific embodiment of the present invention. [Figure 3C] FIG. 1 is a schematic diagram showing a clean room system according to another specific embodiment of the present invention. [Figure 4] FIG. 10 is a schematic diagram showing a clean room module according to another specific embodiment of the present invention. [Figure 5] FIG. 10 is a schematic diagram showing a clean room module according to another specific embodiment of the present invention. DETAILED DESCRIPTION OF THE INVENTION

[0020] In order to make the advantages, spirit, and features of the present invention more easily and clearly understood, specific embodiments will be described and examined in detail below with reference to the accompanying drawings. It should be noted that these specific embodiments are merely representative examples of the present invention, and the specific methods, devices, conditions, materials, etc. exemplified do not limit the present invention or the corresponding specific embodiments. Furthermore, the components in the drawings are used only to indicate their relative positions and are not drawn to scale. Furthermore, the step numbers of the present invention are merely used to distinguish different steps, and do not represent the order of the steps. The above will be explained in advance.

[0021] Please refer to Figure 1. Figure 1 is a schematic diagram showing a clean room system 1 according to a specific embodiment of the present invention. As shown in Figure 1, the clean room system 1 according to this specific embodiment includes a plurality of clean room modules 11, a plurality of docking windows 12, and an automated guided vehicle 13. Each clean room module 11 is 、 Quickly assemble with each other Be Then, a step for forming an inner space 112 and an outer area 113 is performed. Equipped with a plurality of partition plates 111 The docking windows 12 are installed on the partitions 111 of the partitions 111 of each clean room module 11, and each docking window 12 is used as a passage (not shown) between the corresponding internal space 112 and external area 113. An automated guided vehicle 13 travels in the external area 113. The automated guided vehicle 13 transports an outer box 90 containing an item 91 through the passage corresponding to the docking window 12.

[0022] In practice, clean room system 1 is applied to a cell factory. Contract development and manufacturing service format (Contract Development and Manufacturing Organization, CDMO) cell factory. Here, each partition plate is a movable partition plate, and the material of the partition plate may be stainless steel, aluminum alloy, high pressure laminate (HPL), or other composite material. Each partition plate is , ShiQuickly attach or detach dividers via connecting members such as bolt strips, tenons, or connecting clips. and make it possible Furthermore, the internal space of a clean room system that combines multiple movable partitions is an airtight space, and by maintaining positive pressure and laminar flow, the internal space's cleanliness class can reach Class 4 (compliant with ISO8 standards). In practice, the materials and connecting members of the partitions are not limited to these and can be adjusted based on production needs or specifications.

[0023] For example, the periphery of each partition is medical-grade. Noshi A cooling strip is provided. . The cooling strip is fixed to the periphery of the partition board through a slot or recessed design, and the partition boards are connected with fastening elements (e.g., tenons, joint clamps, concealed joints, magnetic fasteners, etc.), thereby realizing a strong connection and ensuring good airtightness. In another embodiment, each partition board further has a concave-convex structure on the periphery, and the surface of each concave-convex structure has a concave-convex structure on the entire surface. Teshi The rail strip is laid and precise docking of the uneven structure is performed. and With the aid of rail strips, the partition plates can be firmly connected to one another. In another embodiment, rails, circuit modules, and sensors are further provided inside the cell factory. The circuit modules are used in combination with the rails to automatically transport the partition plates to a designated position, and sensors are also used to perform real-time airtightness inspection of the joints. As a result, the clean room system provided by the present invention can not only improve the efficiency of assembling and removing partition plates, but also quickly and flexibly plan the space required for each schedule according to production demand, and quickly and automatically assemble multiple internal areas. By Improve the flexibility and production efficiency of the entire cell factory too can.

[0024] Furthermore, the partitions, which can be quickly assembled and removed, allow each clean room module to be independent and isolated. Therefore, when the clean room system of the present invention is applied to a CDMO cell factory, even if equipment in the cell factory needs to be shut down, the number of clean room modules can be adjusted or the clean room modules can be moved to different positions depending on the length of the downtime maintenance period or the situation of the current equipment. death Alternatively, each clean room module can be shut down independently or in rotation depending on the equipment inside, and the traffic routes of each clean room and automated guided vehicle within the cell factory can be readjusted based on the current schedule. In this way, when the cell factory faces a need for shutdown, the clean room system of the present invention not only effectively avoids the conventional situation in which the entire factory must be shut down and production lines are halted, but also allows the clean room modules within the cell factory to be moved to appropriate positions according to the adjusted production line routes, or to be quickly removed and the allocation of internal production lines adjusted. In this way, the clean room system provided by the present invention not only improves the flexibility of the traffic routes within the cell factory as a whole, but also provides necessary adjustments to meet future market demands, allowing the cell factory to maintain a certain production capacity.

[0025] When an automated guided vehicle (AGV) is applied to a cell factory, Interior cabin The system can maintain laminar flow and positive pressure to ensure cleanliness and safety during transport of goods (e.g., raw materials). Interior cabinThe automated guided vehicles are equipped with sterilization equipment such as hydrogen peroxide sterilization and ultraviolet disinfection to further prevent cross-contamination. Furthermore, automated guided vehicles can be docked with various specialized equipment, including isolators, restricted access barrier systems (RABS), biosafety cabinets (BSCs), and material airlocks (MALs). This allows for further separation of raw materials and waste through the above-specified automated guided vehicles. In another embodiment, when an automated guided vehicle transports different materials, corresponding light signals or traffic lights can be displayed on the automated guided vehicle to further avoid confusion. Furthermore, to further ensure the production environment within the cell factory, the automated guided vehicles are further equipped with a particle monitoring function, which can monitor the surrounding particle count in real time and ensure that the cleanliness of the environment during travel meets the standard. The automated guided vehicle system also has a smart scheduling function, which can automatically adjust the power and Interior cabin This allows for automatic allocation of transport tasks according to the sterilization status of the container, improving transport efficiency within the cell factory.

[0026] The automated guided vehicle of the present invention can transport articles by the following several methods. In an embodiment, rails can be pre-installed in the clean room system. The automated guided vehicle can travel along the pre-installed rails, and the rails are magnetic strip Alternatively, the automated guided vehicle may be mounted on actual rails, ensuring that the automated guided vehicle travels along a fixed route. In another embodiment, the automated guided vehicle may be positioned on a non-rail system, such as by laser light, visual recognition, or by using a map of the CDMO cell factory. By , allowing automated guided vehicles to move freely within CDMO cell factories without relying on physical rails. It may be This allows for flexible scheduling or changes in equipment configuration within the CDMO cell factory. By doing , suitable for more complex and diverse production environments can beIn another embodiment, the automated guided vehicles are further integrated with the CDMO cell factory's central control system, allowing for remote control of the transportation and dispatch of the automated guided vehicles, and also real-time monitoring of the running status and power status of each automated guided vehicle. This not only improves transportation efficiency, but also makes it possible to monitor whether there are any errors in the automated guided vehicle's transportation routes and schedules. As a result, it is possible to achieve highly efficient and highly accurate automatic transportation of raw materials and waste.

[0027] Please refer to Figure 2. Figure 2 is a schematic diagram showing the docking window 12 in a specific embodiment of the present invention. As shown in Figure 2, the docking window 12 on each clean room module teeth Each cell factory may further include a first docking window 121 and a second docking window 122. It should be noted that the geometric shape of the first docking window 121 is different from that of the second docking window 122. As shown in FIG. 2, the geometric shape of the first docking window 121 is rectangular, and the geometric shape of the second docking window 122 is circular. Furthermore, the cross section of the first outer box 901 containing the first item is rectangular, and the cross section of the second outer box 902 containing the second item is circular. The automated guided vehicle can transport the first item (e.g., raw materials) to the internal space through the first docking window 121 and the second item (e.g., waste) to the external area through the second docking window 122. Therefore, the difference in the outer shapes of the two docking windows helps to distinguish them during transportation, further avoiding the risk of the automated guided vehicle mistakenly transporting or picking up the first or second item, and improving accuracy during cell factory operation. sex Further improve do.In another embodiment, the clean room system includes a first automated guided vehicle and a second automated guided vehicle, each of which transports a different type of specific item. For example, the first automated guided vehicle transports a first item (e.g., raw materials) and is dedicated to entering the interior space through the first docking window, while the second automated guided vehicle transports a second item (e.g., waste) and is dedicated to transporting the second item to the exterior area through the second docking window. In this way, the clean room system of the present invention can effectively improve the accurate transportation of materials and also effectively reduce the risk of cross-contamination.

[0028] In addition, various production Style To meet the production demands of the above, the present invention also provides other forms of clean room systems. Please refer to Figures 3A, 3B, and 3C. Figure 3A is a schematic diagram of a clean room system 2 according to another specific embodiment of the present invention, Figure 3B is a schematic diagram of a clean room system 3 according to another specific embodiment of the present invention, and Figure 3C is a schematic diagram of a clean room system 4 according to another specific embodiment of the present invention. Please note that for clarity of the drawings, Figures 3A, 3B, and 3C only show clean room modules, partitions, and automated guided vehicles. As shown in Figure 3A, the number of partitions 111 used in each clean room module 11 is four, and the number of clean room modules 11 in the clean room system 2 of this embodiment is six. The automated guided vehicles 13 travel in the external area and can automatically transport items (e.g., raw materials) into designated clean room modules according to a schedule. As shown in Figure 3B, the number of partitions 111 used in each clean room module 14 is three, and BookIn the embodiment, the clean room system 3 includes six clean room modules 14. The automated guided vehicles 13 travel through the external area and automatically transport items (e.g., raw materials) into designated clean room modules according to a schedule. As shown in FIG. 3C, a pair of partitions 111 are shared between each clean room module 15. Therefore, the number of clean room modules 15 is four. Furthermore, the docking windows of some clean room modules 15 are located in the first external area 113A, and the docking windows of the other clean room modules 15 are located in the second external area 113B. The first automated guided vehicle 131A travels only in the first external area 113A and transports only specific items (e.g., raw materials). The second automated guided vehicle 131B travels only in the second external area 113B and transports only specific items (e.g., waste). The first automated guided vehicle 131A and the second automated guided vehicle 131B can also travel in the directions indicated by the arrows in FIG. 3C. Therefore, the clean room system provided by the present invention can be configured with different numbers of partition plates according to production needs. Adjust the Shows different configurations Ruko This allows for the space utilization rate of the CDMO cell factory to be maximized. Furthermore, the routes of the production lines or automated guided vehicles can be flexibly updated, adjusted, and allocated according to the shutdown status of different equipment, thereby meeting the various production demands of the CDMO cell factory. The number of partitions in the clean room module of the present invention is not limited to these, and in another embodiment, three partitions are used. 1 Consists of four faces of Dividers create a larger space of Clean Room Module Configured as Note that it is also good.

[0029] Please refer to FIG. 4. FIG. 4 is a schematic diagram showing a clean room module 16 according to another specific embodiment of the present invention. As shown in FIG. 4, the clean room module 16 further includes a manipulator 114, which includes a first chuck 1141 and a second chuck (not shown). The first chuck is used to clamp a first outer box 901 containing a first item, and the second chuck is used to clamp a second outer box containing a second item. In practice, the manipulator 114 can accurately identify the first item, the second item, the first outer box, the second outer box, the first docking window, the second docking window, and the cell culture vessel using AI vision recognition. Furthermore, when the manipulator 114 needs to be replaced to clamp a different object, it automatically replaces the chuck corresponding to the raw material or waste (i.e., the first and second items), thereby avoiding cross-contamination. The manipulator transports the first item from the first docking window. Re "This effectively double-checks whether the first outer box delivered is accurate. Furthermore, the manipulator also allows precise cell culture or other cell manufacturing processes to be performed on different cell culture vessels within each clean room module, effectively improving yields and standards within the CDMO cell factory."

[0030] The manipulator can then reconfirm identified items, such as transported raw materials or waste, using AI vision recognition. In practice, AI vision recognition uses deep learning, such as convolutional neural networks (CNNs), to collect a large number of videos or images of raw materials and waste, label them en masse, extract their respective features, and then classify and locate the items based on their characteristics. Furthermore, the manipulator can also recognize and analyze raw materials using AI vision recognition. Furthermore, by integrating with the manipulator system, the manipulator can accurately position cells in a petri dish and perform complex steps, such as cell microinjection, liquid addition, and cell separation. In this way, the cleanroom system of the present invention can achieve automation and perform even more precise operations. It can also effectively improve production yields during operations and reduce the risk of contamination caused by human manipulation in conventional technologies.

[0031] Furthermore, in large-scale CDMO factories, the cell manufacturing process may not be performed on only one floor. When cellular materials in a certain space need to be transported to other floors, the cleanliness of the internal space, the transport process, and the environmental specifications after transport all affect the quality of the materials after transport. The present invention also provides other embodiments. Please refer to FIG. 5. FIG. 5 is a schematic diagram showing a clean room module 17 of another specific embodiment of the present invention. The clean room system further includes a main gas electrotransport device 115 and multiple cell incubators 116. As shown in FIG. 5, the cell incubators 116 in this specific embodiment are installed in the clean room module 17. The main gas electrotransport device 115 is installed on one of the movable partitions of the clean room module 17. Furthermore, the main gas electrotransport device 115 can be reconnected to or mounted on an external main cable device. In practice, when the cell incubators 116 in the clean room module 17 need to be moved to a different floor due to production demand, the clean room modules 17 are combined with a movable partition and the two sets of cell incubators 116 are installed in the clean room module 17. Therefore, there is no need to separately remove the two sets of cell incubators 116 from the clean room module 17, and the clean room module 17 can be moved directly to another floor. Therefore, the cell incubators 116 tooThe clean room module 17 is not contaminated by moving the cell culture vessels 116. Furthermore, the main gas electrotransport device 115 is installed on the clean room module 17 and simultaneously connects to the two cell culture vessels 116 therein. Therefore, when the clean room module 17 is moved to another floor, the main gas electrotransport device 115 on the clean room module 17 can be directly connected to the electrical wiring and gas piping of that floor. After connection, the clean room module 17 simultaneously connects the air pressure and electrical wiring of the two cell culture vessels 116 therein via the gas piping unit 1151 and the electrical wiring unit 1152 of the main gas electrotransport device 115, in accordance with the power and gas transmission specifications of that floor. This not only ensures uniform and stable gas and power supply within the clean room module, but also meets the flexible and diverse production needs of the cell factory. While the number of cell culture vessels in this embodiment is two, it should be noted that in practice, the number and size of the cell culture vessels and the specifications of the main gas electrotransport device can all be adjusted or designed according to usage needs.

[0032] As described above, the present invention provides a cleanroom system whose cleanroom modules can be quickly and flexibly assembled or disassembled to suit the production line configuration based on the schedule of a CDMO cell factory. Furthermore, the present invention distinguishes between docking windows depending on the transported items. For example, raw materials are delivered only through specific automated guided vehicles and corresponding geometric windows. This effectively avoids the risk of cross-contamination between raw materials and waste. Furthermore, each cleanroom module in the cleanroom system of the present invention is independent and isolated. Therefore, when the cleanroom system of the present invention is applied to a CDMO cell factory, even if equipment in the cell factory needs to be shut down, it can be shut down independently or sequentially based on the shutdown cycle of the equipment within each cleanroom module. Furthermore, the flow paths of each cleanroom and automated guided vehicle within the cell factory can be re-adjusted based on the current schedule. Compared to prior art, the cleanroom system provided by the present invention effectively solves the problem of the entire production line stalling due to shutdowns. In addition, the modules of each clean room module can be flexibly adjusted based on the production line plan, which can effectively improve the production capacity of the entire cell factory.

[0033] Each clean room module in the clean room system of the present invention further includes a manipulator. By combining the manipulator with AI vision recognition, the accuracy of raw material transportation can be reconfirmed. The manipulator in the clean room module can also perform precise cell culture operations on the cell culture vessels inside. Compared with prior art, the clean room system of the present invention can improve production capacity and stabilize the production yield of the cell factory. In addition, the clean room system of the present invention can also install a main gas electrotransport device in a specific clean room module, connecting each cell culture vessel in the clean room module through the main gas electrotransport device to form a unified supply system. This reduces the complex verification requirements after replacing the cell culture vessel, thereby improving work and production efficiency.

[0034] The detailed description of the preferred specific embodiments above is intended to more clearly explain the features and spirit of the present invention, and the preferred specific embodiments disclosed above are not intended to limit the scope of the present invention. On the contrary, the intention is to include all modifications and equivalent structures within the scope of the claims to be filed by the present invention. Therefore, the scope of the claims to be filed by the present invention should be interpreted in the broadest possible manner based on the above description so as to include all possible modifications and equivalent structures. [Explanation of symbols]

[0035] 1, 2, 3, 4: Cleanroom system 11, 14, 15, 16, 17: Clean room modules 111: Partition board 112: Interior space 113: External Area 113A: First External Area 113B: Second External Area 114: Manipulator 1141: First chuck 115: Main gas electric transmission equipment 1151: Gas piping unit 1152: Electrical wiring unit 116: Cell culture vessel 12: Docking window 121: First docking window 122: Second docking window 13:Automated guided vehicle 131A: First automated guided vehicle 131B: 2nd automated guided vehicle 90: Outer box 901: First outer box 902: Second outer box 91: Goods

Claims

1. 1. A clean room system comprising: a plurality of cleanroom modules with a plurality of dividers for rapid assembly to form an interior space and an exterior area; a plurality of docking windows respectively installed on the partitions of the partitions of each clean room module and used as passages between the corresponding internal spaces and the external areas; A clean room system comprising an automated guided vehicle that travels through the external area and transports items through the passageway corresponding to the docking window.

2. The clean room system of claim 1, wherein the clean room system is applied to a cell factory, the cell factory being a cell factory of a contract development and manufacturing organization (CDMO), each partition plate is a movable partition plate, the internal space of each clean room module is an airtight space, and positive pressure and laminar flow are maintained in the airtight space so that the internal space of the clean room module reaches a predetermined cleanliness class.

3. 3. The clean room system of claim 2, further comprising a main gas electrotransport device and a plurality of cell incubators, wherein the cell incubators are installed within a clean room module of the clean room modules, and the main gas electrotransport device is installed on one of the movable partition plates of the clean room module, and the main gas electrotransport device is connected to the clean room module and the cell incubators.

4. 4. The clean room system according to claim 3, wherein the main gas electrotransport device further comprises a gas piping unit and an electrical wiring unit, and the cell culture vessels form a unified supply source for each cell culture vessel through the main gas electrotransport device.

5. The clean room system of claim 3, wherein each docking window further comprises a first docking window and a second docking window, the items further comprise a first item and a second item, the automated guided vehicle is for transporting the first item to the interior space through the first docking window and the second item to the exterior area through the second docking window, and the geometric outline of the first docking window is different from the geometric outline of the second docking window.

6. 6. The clean room system of claim 5, wherein each clean room module further comprises a manipulator, the manipulator comprising a first chuck and a second chuck, the first chuck for clamping the first item, and the second chuck for clamping the second item.

7. The clean room system of claim 6, wherein the manipulator is configured to recognize and position the first item, the second item, the first docking window, the second docking window, and the cell culture vessel using AI vision.

8. The clean room system according to claim 6 , wherein the manipulator further comprises a gravity sensor unit for distinguishing between the first item and the second item.

9. The clean room system according to claim 5, wherein the first item is a raw material and the second item is a waste material.

10. The clean room system of claim 2, wherein when the cell factory assigns a shutdown or production schedule, the clean room module quickly removes the movable partition panel to match a particular one of the clean room modules to the shutdown or production schedule based on the shutdown or production schedule.

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