Anti-allergen agent, Anti-allergen coating composition, laminate, Anti-allergen resin composition, and molded article

Abstract

To provide an anti-allergen agent having high compatibility with a resin and high anti-allergenicity, and reducing the influence on the appearance of an application object.SOLUTION: The anti-allergen agent contains a fatty acid metal salt of a fatty acid having 1-22 carbon atoms and a metal, and the metal is copper or bismuth.SELECTED DRAWING: None

Description

[Technical Field]

[0001] The present invention relates to an antiallergenic agent, an antiallergenic coating composition, a laminate, an antiallergenic resin composition, and a molded article. [Background technology]

[0002] Many people suffer from allergic diseases such as asthma, atopic dermatitis, and allergic rhinitis, and the incidence of these diseases has been increasing in recent years. These allergic diseases are caused by various allergens present in the environment, including dust mites, pet hair, pollen, and mold, which are well-known as typical inhalant allergens.

[0003] A widely known method for removing airborne allergens is to use air conditioners or air purifiers to filter the air. However, this results in the allergens collecting in the filter, and there is a risk of the allergens being re-dispersed when the filter is replaced. Similarly, while vacuum cleaners are effective for removing allergens that have accumulated on the floor, they simply collect the allergens in a dust bag, and there is a risk of the allergens being re-dispersed when the bag is discarded.

[0004] In addition to the above, masks are commonly used to prevent inhaling pollen from cedar and other grains, but the allergenicity of pollen that adheres to the mask does not disappear, and there is a risk that it will be absorbed when it is re-dispersed.

[0005] Conventional countermeasures against allergens have mainly involved collecting the allergens, and there has been a demand for a means to inactivate the allergenicity of the allergens themselves. In response to this demand, various anti-allergen agents have been proposed (e.g., Patent Documents 1 and 2). [Prior art documents] [Patent documents]

[0006] [Patent Document 1] Japanese Patent Application Laid-Open No. 2006-241431 [Patent Document 2] Japanese Patent Application Laid-Open No. 2007-145742 Summary of the Invention [Problem to be solved by the invention]

[0007] The antiallergenic agent in Patent Document 1 is an inorganic salt compound, and when added to a coating composition containing a binder resin, for example, the inorganic salt compound has the problem of becoming cloudy and impairing the appearance due to insufficient compatibility with the binder resin, and also has the problem of the antiallergenicity of the coating surface being easily reduced due to the inorganic salt compound being water-soluble. The titanium oxide used as the anti-allergen agent in Patent Document 2 utilizes its photocatalytic effect, and therefore sufficient anti-allergenicity cannot be expected, for example, in dark indoor locations. In addition, like the inorganic salt compound in Patent Document 1, titanium oxide has insufficient compatibility with binder resins, which causes the agent to become cloudy and impairs the appearance.

[0008] The problem to be solved by the present invention is to provide an antiallergen agent that has high compatibility with resins, high antiallergenicity, and reduced impact on the appearance of the object to which it is applied. Another problem to be solved by the present invention is to provide an antiallergenic coating composition that can provide an antiallergenic coating without impairing the surface appearance. Another problem to be solved by the present invention is to provide a laminate and a molded article that can exhibit antiallergenicity without impairing the surface appearance. [Means for solving the problem]

[0009] As a result of intensive research to solve the above problems, the inventors discovered that an anti-allergen agent containing a specific fatty acid metal salt exhibits high anti-allergenic properties while ensuring high compatibility with resins, and thus completed the present invention.

[0010] That is, the present invention relates to the following antiallergen agents, etc. 1. An antiallergen agent containing a fatty acid metal salt of a fatty acid having 1 to 22 carbon atoms and a metal, An antiallergen agent wherein the metal is copper or bismuth. 2. The antiallergen agent according to 1, wherein the fatty acid is 2-ethylhexanoic acid, neodecanoic acid, isononanoic acid, naphthenic acid, lauric acid, stearic acid, palmitic acid, myristic acid, isostearic acid or oleic acid. 3. An antiallergenic coating composition containing the antiallergenic agent according to 1 or 2 and a binder resin. 4. The anti-allergenic coating composition according to claim 3, wherein the binder resin is one or more selected from the group consisting of acrylic resin, vinyl acetate resin, styrene resin, vinyl chloride resin, olefin resin, urethane resin, urea resin, urethane urea resin, epoxy resin, melamine resin, phenol resin, polyester resin, alkyd resin, silicone resin, acrylonitrile / styrene copolymer resin, and acrylonitrile / butadiene copolymer resin. 5. The antiallergenic coating composition according to 3 or 4, wherein the metal derived from the antiallergen agent is contained in an amount of 0.01 to 30 parts by mass per 100 parts by mass of the resin solid content. 6. A laminate having a substrate and a coating layer of the antiallergenic coating composition according to any one of 3 to 5. 7. An antiallergenic resin composition containing the antiallergenic agent according to 1 or 2 and a resin. 8. A molded article obtained by molding the antiallergenic resin composition according to 7. [Effects of the Invention]

[0011] The present invention can provide an antiallergen agent that has high compatibility with resins, high antiallergenicity, and reduced impact on the appearance of the object to which it is applied. The present invention provides an antiallergenic coating composition that can be used to form an antiallergenic coating without impairing the surface appearance. The present invention can provide a laminate and a molded article that can exhibit antiallergenicity without impairing the surface appearance. DETAILED DESCRIPTION OF THE INVENTION

[0012] An embodiment of the present invention will be described below. The present invention is not limited to the following embodiment, and can be implemented by making appropriate modifications within the scope that does not impair the effects of the present invention. The compounds in this specification may be derived from fossil resources or biological resources.

[0013] [Antiallergen] The anti-allergen agent of the present invention can reduce the activity of allergens at the site of application.Here, allergens include, for example, antigens that specifically react with the antibodies of people with allergic diseases.Representative allergens include house dust, animal allergens (mites, pets, livestock and their excrement, hair, etc.), plant allergens (tree pollen such as cedar and cypress, grass plant pollen, etc.), fungal allergens, and bacterial allergens.More specifically, pollen allergens include Cry j1, Cry j2, Amb a1, Phl p5, Bet v1, etc.; mite allergens such as Der f1, Der f2, Der p1, Der p2, etc.

[0014] The above-mentioned allergen substances are basically composed of proteins, and the anti-allergen agent of the present invention contains a fatty acid metal salt. It is presumed that the protein coordinates with the metal of the fatty acid metal salt, thereby denaturing the protein and reducing its allergenic activity. The fatty acid metal salt having a fatty chain has high compatibility with the binder resin, and the antiallergenic agent does not precipitate from the coating portion (described later) and impair the appearance. Furthermore, since the fatty acid metal salt is water-insoluble, the fatty acid metal salt on the coating surface (described later) does not dissolve in water and significantly reduce the antiallergenicity. The antiallergen agent of the present invention will now be described.

[0015] (Fatty acid metal salts) The antiallergen agent of the present invention contains a fatty acid metal salt of a fatty acid having 1 to 22 carbon atoms and a metal, and the metal is copper or bismuth. Hereinafter, the fatty acid metal salt may be referred to as the "fatty acid metal salt of the present invention."

[0016] The fatty acid metal salt of the present invention is preferably a compound represented by the following general formula (1).

[0017] [ka] (In the general formula (1), R 1 is a hydrogen atom or an alkyl group having 1 to 21 carbon atoms, n1 is an integer ranging from 1 to 4, M 1 is copper or bismuth.

[0018] In the general formula (1), when n1 is an integer of 2 or more, a plurality of R 1 may be the same as or different from each other.

[0019] R 1 The alkyl group having 1 to 21 carbon atoms may be a linear alkyl group, a branched alkyl group, or may contain an alicyclic structure. R 1 The alkyl group having 1 to 21 carbon atoms may have one or more carbon-carbon unsaturated bonds.

[0020] R 1 The hydrogen atom or alkyl group having 1 to 21 carbon atoms is used in the production of the fatty acid metal salt. 1It corresponds to a carboxylic acid residue obtained by removing the carboxyl group (COOH) from a carboxylic acid having 1 to 22 carbon atoms, represented by COOH. Examples of the carboxylic acid residue include formic acid residue, acetic acid residue, propionic acid residue, butanoic acid residue, pentanoic acid residue, hexanoic acid residue, 2-ethylbutyric acid residue, heptanoic acid residue, octanoic acid residue, acrylic acid residue, methacrylic acid residue, octylic acid residue (2-ethylhexanoic acid residue), neodecanoic acid residue, naphthenic acid residue, isononanoic acid residue, tung oil acid residue, tall oil fatty acid residue, coconut oil fatty acid residue, soybean oil fatty acid residue, linseed oil fatty acid residue, safflower oil fatty acid residue, dehydrated castor oil fatty acid residue, tung oil fatty acid residue, lauric acid residue, myristic acid residue, palmitic acid residue, myristic acid residue, stearic acid residue, isostearic acid residue, and oleic acid residue.

[0021] R 1 The alkyl group having 1 to 21 carbon atoms is preferably an alkyl group having 1 to 18 carbon atoms, more preferably an alkyl group having 6 to 15 carbon atoms, and even more preferably an alkyl group having 7 to 11 carbon atoms.

[0022] R 1 is preferably a 2-ethylhexanoic acid residue, a neodecanoic acid residue, an isononanoic acid residue, a naphthenic acid residue, a lauric acid residue, a stearic acid residue, a palmitic acid residue, a myristic acid residue, an isostearic acid residue, or an oleic acid residue, and from the viewpoint of transparency, is more preferably a 2-ethylhexanoic acid residue, a neodecanoic acid residue, an isononanoic acid residue, a naphthenic acid residue, or an isostearic acid residue.

[0023] M 1 is preferably bismuth. 1 When the antiallergen is bismuth, the antiallergenic agent can suppress coloration derived from the metal and ensure high transparency.

[0024] n1 is M 1 is a value determined by the ionic valence of the metal atom, for example, M 1 If it is bismuth, n1 will be 3.

[0025] The fatty acid metal salt contained in the antiallergen agent of the present invention may be one type alone, or may be two or more types of fatty acid metal salts having mutually different structures.

[0026] The antiallergen agent of the present invention may contain the fatty acid metal salt of the present invention, and may, for example, consist essentially of the fatty acid metal salt of the present invention. Here, "consist essentially of" means that the content of the fatty acid metal salt is 90% by mass or more, 95% by mass or more, 98% by mass or more, or 100% by mass of the total amount of the antiallergen agent of the present invention.

[0027] The fatty acid metal salt of the present invention can be produced by a known method, and commercially available products may also be used.

[0028] (metal complexes) The fatty acid metal salt of the present invention may be in the form of a metal complex coordinated with a heteroatom-containing ligand.

[0029] The heteroatom-containing ligand that forms the metal complex may be a ligand that contains one or more heteroatoms selected from the group consisting of nitrogen, oxygen, sulfur, and phosphorus in the molecule. Examples of such heteroatom-containing ligands include N-methylmorpholine, pyridine, 1,8-diazabicyclo[5.4.0]undecene-7 (DBU), 1,5-diazabicyclo[4.3.0]nonene-5 (DBN), 1,4-diazabicyclo[2.2.2]octane (DABCO), 4-dimethylaminoamine (DMAP), dicyandiamide (DICY), tri-n-butylamine, dimethylbenzylamine, butylamine, 1,2-propanediamine, 1,2-cyclohexanediamine, octylamine, monoethanolamine, diethanolamine, triethanolamine, 2-[[(2-dimethylamino)ethyl]methylamino]ethanol, picolinic acid, 2,2'-[propane-1,2-diylbis(azanylylidenemethanylylidene)]diphenoxyethanol alcohol, imidazole, 1-methylimidazole, 2-methylimidazole, 4-methylimidazole, 2,4-dimethylimidazole, 1,4-diethylimidazole, 3-aminopropyltrimethoxysilane, 3-aminopropyltriethoxysilane, 3-(N-phenyl)aminopropyltrimethoxysilane, 3-(2-aminoethyl)aminopropyltrimethoxysilane, 3-(2-aminoethyl)aminopropylmethyldimethoxysilane, tetramethylammonium hydroxide, 8-quinolinol amine compounds such as 5-chloro-8-quinolinol, 2,2'-bipyridyl and its derivatives, 2,2'-[propane-1,2-diylbis(azanylylidenemethanylylidene)]diphenol and its derivatives, and 2,2'-methylenebis[6-(2h-benzotriazol-2-yl)-4-tert-octylphenol]; quaternary ammonium salts such as trioctylmethylammonium chloride and trioctylmethylammonium acetate; phosphine compounds such as trimethylphosphine, tributylphosphine, and triphenylphosphine; phosphonium salts such as tetramethylphosphonium chloride, tetraethylphosphonium chloride, tetrapropylphosphonium chloride, tetrabutylphosphonium chloride, tetrabutylphosphonium bromide, trimethyl(2-hydroxypropyl)phosphonium chloride, triphenylphosphonium chloride, and benzylphosphonium chloride; and sulfur-based compounds such as thiolactic acid, 2-aminothiophenol, and 2,2'-dithiodianiline.

[0030] The heteroatom-containing ligand is preferably one or more amine ligands selected from picolinic acid, 2-{[(2-dimethylamino)ethyl]methylamino}ethanol, 1,2-propanediamine, 1,2-cyclohexanediamine, monoethanolamine, diethanolamine, triethanolamine, imidazole, 1-methylimidazole, 2-methylimidazole, 4-methylimidazole, 2,4-dimethylimidazole, 1,4-diethylimidazole, 8-quinolinol, 5-chloro-8-quinolinol, 2,2′-bipyridyl and its derivatives, and 2,2′-[propane-1,2-diylbis(azanylylidenemethanylylidene)]diphenol and its derivatives.

[0031] The heteroatom-containing ligand that forms the metal complex may be of one type alone or of two or more types that are different in structure from each other.

[0032] In the metal complex, the ratio (molar ratio) of the fatty acid metal salt to the heteroatom-containing ligand is, for example, in the range of 0.1 to 12 moles, preferably 0.3 to 10 moles, and more preferably 0.5 to 10 moles, of the heteroatom-containing ligand per mole of the metal atom of the fatty acid metal salt.

[0033] The metal complex of a fatty acid metal salt and a heteroatom-containing ligand can be produced by a known method, for example, by reacting a fatty acid metal salt with a heteroatom-containing ligand. Alternatively, a commercially available metal complex may be used.

[0034] [Coating composition] The coating composition of the present invention contains the antiallergen agent of the present invention and a binder resin. Since the antiallergen agent of the present invention has high compatibility with binder resins, the coating layer obtained from the coating composition containing the antiallergen agent of the present invention exhibits antiallergenic properties, while at the same time reducing the effects on the surface appearance of the coating layer, such as damage to the surface appearance due to precipitation of the antiallergen agent, etc.

[0035] The content of the antiallergen agent of the present invention in the coating composition of the present invention is not particularly limited, and for example, the metal derived from the antiallergen agent may be contained in a range of 0.01 to 30 parts by mass per 100 parts by mass of resin solid content, preferably in a range of 0.01 to 20 parts by mass per 100 parts by mass of resin solid content, more preferably in a range of 0.05 to 10 parts by mass per 100 parts by mass of resin solid content, even more preferably in a range of 0.1 to 5 parts by mass per 100 parts by mass of resin solid content, and particularly preferably in a range of 0.1 to 3 parts by mass per 100 parts by mass of resin solid content. Here, the term "resin solid content" refers to the total amount of solid content such as binder resin other than the solvent contained in the coating composition.

[0036] The curing properties of the binder resin contained in the coating composition of the present invention are not particularly limited. For example, when the binder resin is an acrylic resin, the acrylic resin may be a thermosetting acrylic resin or an active energy ray-curable acrylic resin. The binder resin is not particularly limited in form, and may be an emulsion resin or a latex resin.

[0037] The binder resin may be either a water-based resin or a water-insoluble resin (solvent-based resin). In this application, the term "water-soluble resin" means that the amount of water required to dissolve 1 g of resin at 20° C. is less than 10 ml. The term "water-insoluble resin" refers to a resin that is not one of the aforementioned "water-soluble resins."

[0038] Specific examples of binder resins include acrylic resin, vinyl acetate resin, styrene resin, vinyl chloride resin, olefin resin, urethane resin, urea resin, urethane urea resin, acrylic urethane resin, epoxy resin, melamine resin, phenol resin, polyester resin, alkyd resin, silicone resin, polyphenylene sulfide resin, acrylonitrile / styrene copolymer resin, acrylonitrile / butadiene copolymer resin, and acrylonitrile / butadiene / styrene copolymer (ABS) resin. The binder resin also includes modified versions of the above resins, and for example, in the case of phenolic resin, it also includes rosin-modified phenolic resin.

[0039] The binder resin contained in the coating composition of the present invention may be one type alone or two or more types.

[0040] The content of the binder resin in the coating composition of the present invention is not particularly limited, and may be appropriately set within the range of, for example, 10 to 99.9 mass % of the total solid content of the coating composition.

[0041] The coating composition of the present invention only needs to contain the antiallergen agent of the present invention and a binder resin, and may further contain a dispersion medium. The dispersion medium is added for the purpose of adjusting the viscosity of the coating composition, and may be either an aqueous medium or an oil-based medium.

[0042] Specific examples of the dispersion medium include water, monofunctional alcohols such as 1-butanol, isobutanol, 1-pentanol, 2-methyl-2-pentanol, 3-methyl-3-pentanol, methyl ethyl ketone, methanol, ethanol, n-propyl alcohol, and isopropyl alcohol, various diols, polyhydric alcohols such as glycerin, ethylene glycol, 1,2-propanediol, 1,3-propanediol, 1,4-butanediol, 1,6-hexanediol, 1,8-octanediol, and 1,9- Diols such as nonanediol, 1,10-decanediol, 1,12-dodecanediol, propylene glycol, 1,2-butanediol, 3-methyl-1,3 butanediol, 1,2-pentanediol, 2-methyl-1,3 propanediol, 1,2-hexanediol, dipropylene glycol, and diethylene glycol; aromatic diols which are adducts of bisphenol A with alkylene oxides having 2 or 3 carbon atoms (average number of added moles: 1 to 16); and hydrogenated bisphenol A. alicyclic diols such as polyoxypropylene-2,2-bis(4-hydroxyphenyl)propane, polyoxyethylene-2,2-bis(4-hydroxyphenyl)propane, cyclohexanediol, ethylene glycol monomethyl ether, ethylene glycol monoisopropyl ether, ethylene glycol monobutyl ether, ethylene glycol monoisobutyl ether, diethylene glycol monomethyl ether, diethylene glycol monoisopropyl ether, diethylene glycol monobutyl ether, diethylene glycol monoisobutyl ether, propylene glycol monomethyl ether, propylene glycol monopropyl ether, dipropylene glycol monomethyl ether, tripropylene glycol monomethyl ether, diethylene glycol dimethyl ether, diethylene glycol methyl ethyl ether, diethylene glycol diethyl ether, triethylene glycol dimethyl ether, ethyl carbitol, γ-butyrolactone, and various fatty acids.

[0043] The dispersion medium contained in the coating composition of the present invention may be one type alone or two or more types.

[0044] The content of the dispersion medium in the coating composition of the present invention is not particularly limited, and may be appropriately set so that the solid content of the coating composition falls within the range of 30 to 80% by mass, for example.

[0045] The coating composition of the present invention may further contain a plasticizer. Addition of a plasticizer to the coating composition can impart flexibility to the resulting coating layer and improve its ability to conform to the substrate.

[0046] The plasticizer is not particularly limited, and examples thereof include phthalate esters, non-aromatic dibasic acid esters, aliphatic esters, esters of polyalkylene glycols, phosphate esters, trimellitate esters, chlorinated paraffins, hydrocarbon oils, process oils, polyethers, epoxy plasticizers, and polyester plasticizers, with phthalate esters being preferred. Specific examples of plasticizers include dibutyl phthalate, diheptyl phthalate, di(2-ethylhexyl) phthalate, dioctyl phthalate, dioctyl adipate, dioctyl sebacate, dibutyl sebacate, isodecyl succinate, tricresyl phosphate, tributyl phosphate, epoxidized soybean oil, and benzyl epoxy stearate.

[0047] The coating composition of the present invention may contain one type of plasticizer alone or two or more types of plasticizers.

[0048] The content of the plasticizer in the coating composition of the present invention is not particularly limited, and may be appropriately set within the range of, for example, 0.1 to 50 parts by mass per 100 parts by mass of the resin solid content of the coating composition.

[0049] The coating composition of the present invention only needs to contain the antiallergen agent of the present invention, a binder resin, and optionally a dispersion medium and / or a plasticizer, and may also contain other additives within a range that does not impair the effects of the present invention. Examples of such other additives include pigments, matting agents, curing agents, curing accelerators, antifoaming agents, dispersants, leveling agents, thickeners, antioxidants, weathering agents, flame retardants, antistatic agents, lubricants, preservatives, antibacterial and antiviral agents, antialgal agents, antiallergens, antibiofilm agents, antifungal agents, and preservatives.

[0050] The coating layer of the coating composition of the present invention may be a cured film obtained by curing the coating composition, or may be an uncured film of the coating composition. When the coating layer is a cured coating film of a coating composition, the coating composition of the present invention may be applied to the surface of a substrate, and the resulting coating film may be cured by a method suitable for the binder resin (thermal curing, active energy ray curing, etc.).

[0051] The coating composition can be applied by any known and commonly used coating method, such as a roll coater, electrostatic coating, bar coater, gravure coater, knife coater, dipping coating, or spray coating.

[0052] The substrate to be coated is not particularly limited, and examples thereof include paper, synthetic paper, steel plate, aluminum foil, glass, wood, woven fabric, knitted fabric, nonwoven fabric, gypsum board, wooden board, and resin substrate.

[0053] Specific examples of the resin substrate include polyethylene terephthalate (PET) film, polystyrene film, polyamide film, polyacrylonitrile film, polyethylene film (LLDPE: low-density polyethylene film, HDPE: high-density polyethylene film), polypropylene film (CPP: unstretched polypropylene film, OPP: biaxially oriented polypropylene film), polyvinyl alcohol film, ethylene-vinyl alcohol copolymer film, polycarbonate film, polyethylene terephthalate film, polymethyl methacrylate film, polystyrene film, polyester film, polyolefin film, epoxy resin film, melamine resin film, triacetyl cellulose resin film, polyvinyl alcohol film, ABS resin film, norbornene-based resin film, cyclic olefin-based resin film, polyimide resin film, polyvinyl fluoride resin film, polyvinylidene fluoride resin film, ethylene-vinyl acetate copolymer film, etc. The resin substrate to be used may be subjected to a surface treatment such as a corona treatment.

[0054] [Resin composition] The resin composition of the present invention contains the antiallergen agent of the present invention and a resin. The resin composition containing the antiallergenic agent of the present invention can be used not only for coating applications, but also for molding into a molded article exhibiting antiallergenic properties, and can be applied to locations in the living environment where people may come into contact with the article.

[0055] The resin contained in the resin composition of the present invention can be the same as the binder resin contained in the coating composition of the present invention. Furthermore, the resin composition of the present invention can contain the same components as those that can be contained in the coating composition of the present invention.

[0056] The resin composition of the present invention can be molded by any molding method suitable for the resin used, including melt molding methods such as injection molding, extrusion molding, pressure molding (press molding), compressed air molding, and vacuum molding, and casting methods.

[0057] The coating layer obtained using the coating composition of the present invention and the molded article obtained using the resin composition of the present invention can be used as materials having antiallergenic properties.

[0058] The above-mentioned application areas include textile products (clothing, carpets, sofas, etc.), interior items (wallpaper, curtains, etc.), bedding (futon covers, futon batting, sheets, pillowcases, mats, etc.), automotive parts (car seats, car mats, ceiling and floor materials, etc.), nonwoven fabric products (wet cleaning wipers, masks, filter materials, vacuum cleaner dust bags, etc.), stuffed toys, etc.

[0059] The antiallergen agent of the present invention can also be used in fabric softeners, deodorants, antifungal agents, disinfectants, insecticides, paints, adhesives, etc. to reduce allergens in the living environment. [Example]

[0060] The present invention will be specifically described below with reference to examples and comparative examples. The present invention is not limited to the following examples.

[0061] (Synthesis Example 1: Preparation of bismuth octoate) 330.6 parts by mass of octylic acid and 125.0 parts by mass of bismuth oxide were reacted at 130°C, and after dehydration under reduced pressure at 130°C, 439.5 parts by mass of a bismuth octylate (bismuth 2-ethylhexanoate) solution was obtained. The bismuth content in the obtained bismuth octylate was 25% by mass.

[0062] (Synthesis Example 2: Preparation of copper neodecanoate) 217.1 parts by mass of neodecanoic acid and 36.0 parts by mass of sodium hydroxide were reacted at 80°C, and 100.0 parts by mass of copper sulfate was added and reacted at 80°C. After washing the by-product sodium sulfate with water, the mixture was dehydrated under reduced pressure at 130°C, and 76.2 parts by mass of a petroleum hydrocarbon was added to obtain 301.6 parts by mass of a copper neodecanoate solution. The copper content in the obtained copper neodecanoate was 8% by mass.

[0063] Comparative Synthesis Example 1: Preparation of neodymium neodecanoate 224.8 parts by mass of neodecanoic acid and 60.0 parts by mass of neodymium oxide were reacted at 130°C, and after dehydration under reduced pressure at 130°C, 306.9 parts by mass of cyclohexane was added to obtain 570.0 parts by mass of a neodymium neodecanoate solution. The neodymium content in the resulting neodymium neodecanoate was 8.8% by mass.

[0064] (Examples 1 and 2 and Comparative Example 1: Production of urethane resin coated substrate) The antiallergen agent shown in Table 1 was added to a urethane resin (DIC Corporation's "Burnoc 16-416") in the amount shown in Table 1 to prepare each coating composition. The prepared coating composition was applied to a 50 mm x 50 mm x 2 mm glass plate using an applicator to a wet film thickness of 152 μm, and the resulting coated substrate was dried overnight at room temperature, followed by additional drying at 80 ° C for 1 hour to produce an anti-allergen sample, which is a laminate of a urethane resin coating layer and a glass plate. The urethane resin coating layers of Examples 1 and 2 were both clear and transparent, and Example 1 was not colored. The following antiallergenicity test was carried out using the produced antiallergenic samples, and the results are shown in Table 1.

[0065] (mite allergen test) The mite allergen Derf1 (mite (Df) culture medium extract, manufactured by ITEA Corporation) was dissolved in phosphate buffer solution (PBS-T) to prepare a 30 ng / ml Derf1 solution as a test solution. 0.4 ml of this test solution was dropped onto the coating layer of the anti-allergen sample, covered with polyethylene film, and left to stand at a temperature of 25°C and a humidity of 90% or higher for 24 hours. The test solution was then recovered from the anti-allergen sample, and the amount of Derf1 (sample allergen amount) was measured by sandwich ELISA (enzyme-linked immunosorbent assay) using a Derf1 ELISA kit (ITEA Corporation). Separately, the amount of Derf1 (blank allergen amount) in the test solution was measured after leaving it undisturbed for 24 hours at a temperature of 25°C and a humidity of 90% or more without contacting the anti-allergen sample, and the allergen reduction rate was calculated as 100 x (blank allergen amount - sample allergen amount) / blank allergen amount. The results are shown in Table 1.

[0066] (Pollen allergen test) The pollen allergen test was conducted in the same manner as the mite allergen test, except that the cedar pollen allergen Cryj1 was used instead of the mite allergen Derf1, and the Cryj1 ELISA kit (ITEA Corporation) was used instead of the Derf1 ELISA kit, and the allergen reduction rate was calculated. The results are shown in Table 1.

[0067] [Table 1]

[0068] Regarding the metal content in Table 1, the numbers indicate the percentage of metal content derived from fatty acid metal salts. For example, in Example 1, this means that the content of bismuth derived from bismuth octoate was 0.313 mass % of the total resin solid content of the coating composition.

[0069] As can be seen from Table 1, both bismuth octoate and copper neodecanoate achieved sufficient allergen reduction rates. Example 1 also shows that a high effect can be achieved with a small amount of addition. On the other hand, Comparative Example 1 uses neodymium neodecanoate, a metal soap, but it can be seen that no anti-allergenic properties are achieved at all simply because the metal type is different.

Claims

1. An antiallergen agent containing a fatty acid metal salt of a fatty acid having 1 to 22 carbon atoms and a metal, An antiallergen agent wherein the metal is copper or bismuth.

2. 2. The antiallergen agent according to claim 1, wherein the fatty acid is 2-ethylhexanoic acid, neodecanoic acid, isononanoic acid, naphthenic acid, lauric acid, stearic acid, palmitic acid, myristic acid, isostearic acid, or oleic acid.

3. An antiallergenic coating composition comprising the antiallergenic agent according to claim 1 or 2 and a binder resin.

4. 4. The antiallergenic coating composition according to claim 3, wherein the binder resin is at least one selected from the group consisting of acrylic resins, vinyl acetate resins, styrene resins, vinyl chloride resins, olefin resins, urethane resins, urea resins, urethane urea resins, epoxy resins, melamine resins, phenolic resins, polyester resins, alkyd resins, silicone resins, acrylonitrile / styrene copolymer resins, and acrylonitrile / butadiene copolymer resins.

5. 4. The antiallergenic coating composition according to claim 3, wherein the metal derived from the antiallergen agent is contained in an amount of 0.01 to 30 parts by mass per 100 parts by mass of the resin solid content.

6. A laminate comprising a substrate and a coating layer of the antiallergenic coating composition according to claim 3.

7. An antiallergenic resin composition comprising the antiallergenic agent according to claim 1 or 2 and a resin.

8. A molded article obtained by molding the antiallergenic resin composition according to claim 7.

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