Aerosol generating substrate for vapor absorption, including a semi-solid substrate.

Abstract

To provide an alternative that can offer a more comfortable smoking and / or vaping experience. [Solution] An aerosol generating substrate for vapor inhalation, comprising a semi-solid substrate, is provided, wherein up to about 1.0% of the total weight percentage of the aerosol generating substrate is composed of one or more carboxylic acids dissolved in an alcohol solution. The invention also relates to a method for manufacturing the aerosol generating substrate and its use in an aerosol generating substrate for vapor inhalation.

Description

Technical Field

[0001] The present invention relates to an aerosol generating substrate and a method for producing the same. The present invention also relates to an aerosol generating article containing the aerosol generating substrate.

Background Art

[0002] In recent years, various types of aerosol generating articles and devices for use as a novel form of smoking have been increasing rapidly and are commercially available in the market. These include electrically heated electronic cigarettes (vaping), one of the most well-known novel forms in which an aerosol is generated by heat transfer from a heating element of an aerosol generating device to an aerosol generating substrate or material.

[0003] In non-combustion heated aerosol generating articles, the aerosol forming substrate is reported to be heated at a relatively low temperature, for example, less than 350°C, in order to avoid their combustion. Then, the charge of the inhalable aerosol can be released from the aerosol generating article. The released aerosol is derived from an aerosol forming agent incorporated into a tobacco material that can be particulate or granular.

[0004] Some tobacco blends, especially those provided in the form of e-juice, often cause coughing (also known as a coughing fit) during vaping. One of the reasons contributing to such coughing fits is probably due to the fact that electronic cigarettes have a very large number of inhalation methods for most smokers. Some irritants present in e-liquid may also contribute to coughing fits.

Summary of the Invention

Problems to be Solved by the Invention

[0005] Therefore, it would be desirable to provide a solution to overcome the above problems and to provide an alternative that can provide a more comfortable smoking and / or vaping experience.

[0006] In a further embodiment, an object of the present invention is also to provide a solution for improving the sensory characteristics of the above-mentioned consumables. [Means for solving the problem]

[0007] The inventors of this invention have found a solution to the above problem through an aerosol generating substrate for an aerosol generating article.

[0008] Accordingly, a first aspect of the present invention is to provide an aerosol generating substrate for vapor absorption, comprising a semi-solid substrate, wherein up to about 1.0% by weight of the total weight percent of the aerosol generating substrate is composed of a carboxylic acid-containing alcohol solution, one or more carboxylic acids dissolved in the alcohol solution, and the semi-solid substrate is provided in the form of a foam.

[0009] Accordingly, a second aspect of the present invention is a method for preparing an aerosol generating substrate for vapor absorption, comprising a semi-solid substrate in the form of a foam, a. A step of providing an aerosol generating substrate comprising one or more components selected from the list consisting of propylene glycol, 1,3-propanediol, glycerol, and water. b. Provide one or more carboxylic acids in an alcohol solution, and subsequently, up to about 1% by weight of the total weight percent of the aerosol generating substrate, the alcohol solution containing one or more carboxylic acids is used. The process involves incorporating one or more carboxylic acid-containing alcohol solutions into an aerosol generating substrate to form a mixture. c. Optionally, adding one or more components selected from the list consisting of gum, nicotine, flavorings, and binders to the mixture. d. A process of continuously mixing the mixture for a specific period of time and heating the mixture to a temperature slightly above room temperature, thereby producing a semi-solid substrate in the form of a foam. The objective is to provide a method that includes this.

[0010] A third aspect of the present invention is to provide an aerosol generating substrate according to the present invention for use in reducing coughing fits caused by inhaling vapor.

[0011] A fourth aspect of the present invention is to provide an aerosol generating substrate that can be obtained according to the present invention.

[0012] The inventors have found that the aerosol generating substrate according to the present invention consists of a small amount of carboxylic acid dissolved in an alcohol solution (up to 1.0% by weight of the total weight percent of the aerosol generating substrate is composed of one or more carboxylic acid-containing alcohol solutions), and that the aerosol generating substrate comprises a semi-solid substrate provided in the form of a foam or tobacco mousse, and that the aerosol generating substrate according to the present invention unexpectedly reduces coughing fits to an acceptable level. Furthermore, it was found that it also has a smooth taste without any unpleasant aftertaste. This effect of reducing coughing fits is particularly pronounced when one or more carboxylic acids, such as stearic acid and / or decanoic acid, are present in the alcohol solution of the aerosol generating substrate.

[0013] According to some embodiments, the aerosol generating substrate comprises a carboxylic acid-containing alcohol solution in an amount of 0.2% to 1% by weight based on the total weight percentage of the aerosol generating substrate, preferably about 0.2%, 0.5%, 0.8% or 1.0% by weight of the carboxylic acid-containing alcohol solution in an amount of 0.0% by weight based on the total weight percentage of the aerosol generating substrate. These ranges or amounts of carboxylic acid present in the mixture are sufficient to reduce throat / cough irritation to an acceptable level.

[0014] According to some embodiments, the carboxylic acid-containing alcohol solution is provided at a concentration of about 0.05 v / v% to about 0.2 v / v%, preferably 0.08 v / v% to 0.15 v / v%, or more preferably about 0.1 v / v%. The concentrations used herein may be provided, for example, as volume percentage (v / v%), molar, or mass percentage.

[0015] According to some embodiments, the carboxylic acid has a hydrocarbon chain length of 9 to 30 carbon atoms, preferably 10 to 20 carbon atoms.

[0016] According to some embodiments, the carboxylic acid is selected from a list consisting of benzoic acid, levulinic acid, D / L-tartaric acid, capric acid, pyruvic acid, citric acid, fumaric acid, D / L-lactic acid, D / L-malic acid, sorbic acid, adipic acid, L-aspartic acid, L-glutamic acid, succinic acid, gluconic acid, linoleic acid, saccharic acid, 3,7-dimethyl-6-octenoic acid, 2-methylpentanoic acid, trans-2-hexenoic acid, caprylic acid, lauric acid, stearic acid, butyric acid, linolenic acid, malonic acid, myristic acid, oleic acid, palmitic acid, phenylacetic acid, propionic acid, valeric acid, decanoic acid, hexanoic acid, and octanoic acid.

[0017] According to some embodiments, the carboxylic acid-containing alcohol solution preferably contains only saturated fatty acids such as stearic acid and / or decanoic acid in stearic acid / decanoic acid ratios of 10 / 90, 20 / 80, 30 / 70, 40 / 60, and 50 / 50.

[0018] According to some embodiments, the carboxylic acid-containing alcohol solution comprises only stearic acid or decanoic acid.

[0019] According to several embodiments, the alcohol solution preferably contains only stearic acid and decanoic acid in stearic acid / decanoic acid ratios of 10 / 90, 20 / 80, 30 / 70, 40 / 60, and 50 / 50. The inventors have found that these two compounds are particularly effective in suppressing throat inflammation, and that stearic acid / decanoic acid ratios from 20 / 80 to 50 / 50 are particularly effective in reducing coughing fits.

[0020] According to some embodiments, the aerosol generating substrate further comprises one or more components selected from the group consisting of propylene glycol, 1,3-propanediol, glycerol, water, gum, fragrance, additives, nicotine, and binder.

[0021] According to some embodiments, the solvent has a pH value in the range of 6 to 7, preferably 6.2 to 6.8, more preferably 6.3 to 6.5. In other embodiments, for example, an acidic state of 4 to 6.9 is preferred.

[0022] According to some variations, the carboxylic acid-containing alcohol solution can be prepared, for example, by first weighing the weights of the components (e.g., the solvent, the solute in either solid or liquid form), mixing the mixture in a bottle, leaving the mixture to stand at room temperature for at least 24 hours until the solute is completely dissolved in the solvent, and finally mixing the mixture before using it for foam production.

[0023] According to some embodiments, the mixture is heated at about 45 °C and / or aerated or mixed over about 5 minutes.

[0024] According to other embodiments, an aerosol-generating substrate in the form of a foam can be prepared, for example, as follows: - A step of preparing a mixture of an aerosol-generating substrate containing propylene glycol, glycerin, water, and a 0.1% carboxylic acid-containing alcohol solution; - A step of mixing the mixture at 45 °C for 6 minutes (e.g., using speed "6" on a Krups machine); - A step of adding gum (preferably within 1 minute) and further mixing at 45 °C for 6 minutes (e.g., using speed "6" on a Krups machine); - A step of adding a tobacco-containing material (preferably within 2 minutes) and further mixing the mixture at 45 °C for 6 minutes (e.g., using speed "6" on a Krups machine); - A step of adding a binder (preferably within 1 minute) and further mixing the mixture at 45 °C for 5 minutes (e.g., using speed "6" on a Krups machine); - A step of putting the foamed aerosol-generating substrate into a mold and heating it in an oven at about 50 °C for about 18 hours.

[0025] "About" or "approximately" with respect to a given numerical value means a value within 10% of the specified value. Unless the context clearly dictates otherwise, all values given in this disclosure are to be understood as being supplemented by the word "about". Under more restrictive conditions, the term is used to include values within 5% of the specified value.

[0026] The indefinite articles "a" or "an" do not exclude a plurality and thus should be treated in a broad sense.

[0027] Unless otherwise defined, technical and scientific terms used in this specification have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. field.

[0028] A tobacco-containing material can be any compound, mixture, particulate matter, and / or solution that contains and / or carries tobacco constituents, such as tobacco, tobacco particles, tobacco flavor, and / or nicotine, whether artificially included or naturally contained in tobacco. In contrast, an example of a non-tobacco-specific flavor that is artificially added would be menthol.

[0029] As used herein, the term "aerosol-generating article" refers to an aerosol-generating article for manufacturing an aerosol that includes an aerosol-generating material that is intended to be heated rather than burned to release a volatile compound capable of forming an aerosol.

[0030] As used herein, the term "aerosol-generating substrate" refers to a material that, when heated, can release a volatile compound capable of forming an aerosol. The aerosol generated from the aerosol-generating material of the aerosol-generating article described herein can be visible or invisible and can include vapors (e.g., fine particles of a substance in gaseous state that are normally liquid or solid at room temperature) as well as droplets of gas and condensed vapor.

[0031] The aerosol-forming agent may be any compound, mixture, or solution that can form an aerosol when heated and / or in a mixture with a tobacco-containing agent. Well-known examples include humectants such as glycerin and propylene glycol, and other alcohols such as ethanol.

[0032] As used herein, the term “semi-solid substrate” refers to a substrate state that is highly viscous and slightly more viscous than a semi-liquid. In other words, a semi-solid substrate does not include solid materials (i.e., rigid and stable shapes), nor liquids or fluids. Examples of “semi-solid substrates” in this invention are, for example, foams, gels, mousses, or highly viscous mucus.

[0033] As used herein, the terms “foam” and “mousse” are interchangeable. In this context, foam refers to an element containing pockets of air or gas trapped in a liquid or non-solid material. For example, a continuous-pore foam should be understood as a foam that can be considered to be formed from a plurality of interconnected pores (formed from a structural material derived from a foam-forming agent cooperating with interacting components such as a foam stabilizer), which may contain a mixture of fluid, particularly foam / liquid aerosol-forming substrate and air, and in contrast to a closed-cell foam, at least a substantial portion of the pores in the foam (e.g., more than 50% by volume) are fluidically connected to one another, and the majority of the pores form separate pockets, each completely enclosed by the pore-forming material to substantially prevent fluid from freely passing between the pores. The mousse formed as described herein is primarily a continuous void mousse, as, after cooling or heating of the aerosol-generating material, vapor is released from the mousse, and based on measurements of the weight of the mousse portion before and after heating, it appears that substantially all of the humectant has been released. This is currently considered inexplicable if the humectant could not reach the surface of the mousse portion by passing through adjacent voids. However, alternative explanations cannot be completely ruled out—for example, closed cells may be opened by rupturing the closed cell walls, perhaps as a result of the pressure of the vaporized gas.

[0034] The electronic cigarette (e-cigarette) or electronic pipe or similar device referred to in the present invention, such as a heated device, is not particularly limited and may be used to provide a user with an aerosol for inhalation. According to a particular embodiment, it includes a mouthpiece, heater, storage section, such as a pod, stick, capsule and housing.

[0035] Where used herein, weight percent should be understood as a weight percent based on the total weight percent of the aerosol-generating substrate, unless otherwise specified. In this disclosure, all quantities are expressed in weight percent unless otherwise explicitly stated or evident from the context. In this disclosure, all quantities further expressed in weight percent are at most 100% by weight. Thus, weight percent are calculated by dividing the mass of each component by, for example, the total mass of the substrate, unless otherwise indicated or evident from the context. In this case, chemical compounds may also be expressed in volume percent, which, accordingly, is within the ordinary capabilities of those skilled in the art.

[0036] Where used herein, volume percent is understood as a volume percent based on the total volume of the substrate unless otherwise specified. In this disclosure, all amounts expressed in volume percent in a particular substrate total 100 volume percent. Thus, volume percent is calculated by dividing the volume of each component by the total volume of the substrate unless otherwise specified or evident from the context.

[0037] Similarly, the permeability value (also known as void volume as used herein) represents the volume percentage of foam or mousse composed of air. The actual permeability value of a sample is estimated using the following procedure: A sample of "foam" is prepared without any action to aerate the "foam" (e.g., foaming or aeration using a venting machine), and the known volume of this unfoamed "foam" / material is measured. Then, a sample of foam is prepared after an aeration process (e.g., a process such as foaming or aeration using a venting machine), and the same known volume of the aerated foam is weighed again, and the percentage reduction in weight is calculated. By assuming that the aeration of the unfoamed material is zero and that air has a negligible weight, this directly leads to an estimate of the permeability value by assuming that the measured weight reduction rate results from the substitution of the unfoamed material with (weightless) air. For example, if it is observed that the weight of the foam is 4% less than that of the same volume of unfoamed material compared to the volume of unfoamed material, it is considered that 4% of the unfoamed material has been replaced with air, meaning that the volume percentage of air is 4%.

[0038] The particle size disclosed in this invention can be measured by any suitable method, such as sieving or laser diffraction, preferably sieving.

[0039] As used herein, (dynamic) viscosity refers to the flow behavior of a liquid. Dynamic viscosity is defined as the internal frictional resistance of a liquid to the application of pressure or shear stress. Dynamic viscosity is expressed in millipascal seconds (mPas) and determined using a rotational viscometer. Viscosity measurements are performed at room temperature, i.e., 22°C.

[0040] As used herein, “cooling step” should be understood as having a temperature of room temperature (approximately 22–24°C) for at least 60 minutes, or a temperature of less than 16°C for at least 10 minutes, or more preferably a temperature of less than 12°C for at least 5 minutes.

[0041] As used herein, “ventilation” should be understood as the introduction of air or gas into a material through an external process. Ventilation is, for example, in Krups Prep&Cook The foaming, beating, mixing, or aeration can be carried out using an aeration machine such as the HP 5031 Mousse Foaming Shuffle, or by spraying air using an aeration machine such as the Mondomix aeration machine. Aeration can be carried out at any suitable temperature. The aeration time may be, for example, 1, 2, 3, 4, 5 or 10 minutes or more. [Modes for carrying out the invention]

[0042] The present invention relates to an improved aerosol generating substrate and a method for producing the aerosol generating substrate. When the aerosol generating (tobacco-containing) substrate of the present invention contains up to 1.0% by weight of carboxylic acid (dissolved in an alcohol solution) of the total weight percent of the aerosol generating substrate, the carboxylic acid-containing aerosol generating substrate has been found to remarkably reduce throat irritation or coughing fits.

[0043] Coughing from vaping is not uncommon among vapers, especially those new to e-cigarettes. Inhaling vapor can trigger unpleasant coughing fits; that is, inhaling the aerosol produced by heating the base material can irritate the urge to cough. Several factors can contribute to such coughing fits. For example, some vapers may be affected by the pure nicotine contained in e-cigarettes, or coughing may be triggered by inhaling too deeply or too quickly, or the advanced settings of the vaporizer may not be fine-tuned accordingly.

[0044] While certain throat irritations are welcomed by tobacco-based aerosols (similar to the so-called "throat kick" desired by tobacco smokers, which is not observed in e-cigarette aerosols), the irritation caused by the aerosol needs to be controlled to avoid the actual urge to cough while consuming e-cigarette materials such as tobacco mousse bases.

[0045] In this case, the inventors investigated possible alternative formulations for aerosol-generating substrates, particularly those aimed at reducing coughing fits. The inventors found that when up to about 1.0% of the total weight percentage of the aerosol-generating substrate consisted of one or more carboxylic acids in an alcohol solution, a remarkable effect was observed in reducing coughing fits (or reducing throat irritation).

[0046] When the aerosol generating substrate includes a semi-solid substrate, the reduction of coughing fits is particularly evident, and it is further disclosed herein that the aerosol generating substrate may be provided in the form of a semi-solid substrate, such as a foam or mousse or a gel. Aerosol generating substrates containing carboxylic acids (especially stearic acid and / or decanoic acid) are thought to be able to vaporize or release the carboxylic acids more efficiently due to a higher surface-to-volume ratio compared to when the aerosol generating substrate is provided in a liquid or solid form, when they are in a semi-solid state, i.e., a foam or gel.

[0047] In the present invention, a foam stabilizer may be further introduced into the aerosol generating substrate. The foam stabilizer is not particularly limited as long as it can stabilize the foam to some extent after its formation. According to certain embodiments, the foam stabilizer of the foam is selected from the group consisting of cellulose gum, hydroxyalkylated carbohydrates, and mixtures thereof. Neither cellulose gum nor hydroxyalkylated carbohydrate is particularly limited. According to certain preferred embodiments, the foam stabilizer is cellulose gum, particularly carboxymethylcellulose, or a derivative thereof. Exemplary preferred cellulose gums that may be used in the present invention are CEKOL® 2000 and / or Ceroga 4550C (CERoeper GmbH), each being purified sodium carboxymethylcellulose. Another class of suitable foam stabilizers is hydroxyalkylated carbohydrates, more preferably cellulose ethers, and derivatives thereof. The cellulose ethers or derivatives thereof that may be used may have at least one substituent selected from the group consisting of methyl, ethyl, hydroxyethyl, and hydroxypropyl groups. It can be further substituted with a linear or branched substituted or unsubstituted alkyl group having 1 to 20 carbon atoms, or an aralkyl group having 7 to 20 carbon atoms. Such groups are preferably bonded by ether bonds. Suitable substituents may be, for example, a hydroxyl group, a carboxyl group having 1 to 4 carbon atoms, etc. According to a particular embodiment, the cellulose ether is hydro The materials are selected from hydroxyethylcellulose, methylcellulose, methylhydroxyethylcellulose, ethylhydroxyethylcellulose, and mixtures thereof. Furthermore, various cellulose gums, mixtures of various hydroxyalkylated carbohydrates, mixtures of one or more cellulose gums and one or more hydroxyalkylated carbohydrates, and derivatives of one or any of them can be used. Further derivatives include salts of these cellulose ethers, preferably alkali metal salts thereof, such as sodium salts and / or potassium salts thereof.

[0048] Similarly, foam-forming agents can be further added to the mixture of aerosol-generating substrates. The foam-forming agents are not particularly limited. According to certain embodiments, the foam-forming agents of the foam are selected from, but are not limited to, agar, gellan gum, lecithin, polyglycerol esters of fatty acids, glycerol esters of fatty acids, sorbitan esters of fatty acids, and / or mixtures thereof. A preferred foam-forming agent is gellan gum. Glycerol esters can be prepared by standard esterification methods. When glycerol esters of fatty acids are used, the foam-forming agents may be compounds such as glycerol monostearate and / or glycerol monooleate. Polyglycerol esters may be prepared by polymerizing glycerin under alkaline conditions and then reacting them with specific fatty acids. Suitable polyglycerol esters may be hexaglycerol monooleate, octaglycerol monostearate, and / or octaglycerol monooleate. The sorbitan ester of the fatty acid used in certain embodiments of the present invention may be sorbitan monostearate, sorbitan monooleate, and / or sorbitan monopalmitate. Furthermore, any possible combination of compounds belonging to the above categories can be used.

[0049] The method of the present invention may also be realized by having a step of mixing an aerosol-generating substrate that is aerated after the addition of a foam stabilizer and / or after the cooling of the mixture. This does not preclude the carrying out of other aeration steps, and according to certain embodiments, one, two, or preferably all of the optional aeration steps are carried out in this method. It is also not precluded that aeration has already been carried out in conjunction with the mixing and / or addition steps.

[0050] The method of aeration is not particularly limited and may include, for example, air injection, air foaming - for example, mixing with a sufficiently large paddle / shuffle and / or sufficient paddle movement and / or a sufficiently slower speed - so that air can be introduced into the mixture and the air can be foamed through the mixture. For example, aeration can be carried out by using a sufficient mixer similar to a mixer for preparing mousse, for example, a Krups Prep&Cook HP 5031 mousse foaming shuffle and / or by air injection using an aeration device such as a Mondomix aeration device. Aeration can be carried out at a suitable temperature, for example, room temperature (approximately 20-24°C), 30-80°C, for example, 35-75°C, preferably 30-60°C (including both ends). In this method, aeration may be carried out, for example, in conjunction with the mixing of ingredients and / or in the step of adding ingredients, when foaming is used.

[0051] For this purpose, it is emphasized that the aerosol generating substrate claimed herein can be converted into a semi-solid state, i.e., a foam, mousse, gel, etc., by the method described above, without further addition of foam-forming agents and / or foam stabilizers. In other words, the aerosol generating substrate of the present invention is a semi-solid substrate.

[0052] According to some embodiments of the present invention, the components for forming the aerosol-generating foam, such as an aerosol-forming agent, a foam-forming agent, a foam stabilizer, a tobacco-containing agent, an inhalant, at least one non-tobacco flavoring, and a solvent, are not particularly limited. The gas used for ventilation is also not particularly limited. It is not limited to, for example, air. Further components may also be mixed in. However, according to certain embodiments, the further components or further components are not mixed in essentially.

[0053] The aerosol-forming agent may further contain water. However, according to certain embodiments, water is not included because water in the aerosol form may burn the user's mouth. Water may be included in an amount of 0 to 15% by weight, for example, 5 to 10% by weight, of the total weight percentage of the foam or aerosol-generating substrate. The embodiments are described below. Appearance 1 Aerosol generating substrate for vapor absorption, comprising a semi-solid substrate, wherein up to about 1.0% by weight of the total weight percent of the aerosol generating substrate is composed of a carboxylic acid-containing alcohol solution, one or more carboxylic acids are dissolved in the alcohol solution, and the semi-solid substrate is provided in the form of a foam. Appearance 2 The aerosol generating substrate according to Embodiment 1, comprising 0.2% to 1% by weight of the carboxylic acid-containing alcohol solution in the total weight percentage of the aerosol generating substrate, preferably about 0.2% by weight, 0.5% by weight, 0.8% by weight, or 1.0% by weight of the carboxylic acid-containing alcohol solution in the total weight percentage of the aerosol generating substrate. Appearance 3 The aerosol generating substrate according to embodiment 1 or 2, wherein the carboxylic acid-containing alcohol solution has a concentration of about 0.05 v / v% to about 0.2 v / v%, preferably 0.08 v / v% to 0.15 v / v%, or more preferably about 0.1 v / v%. Pattern 4 The aerosol generating substrate according to any one of embodiments 1 to 3, wherein the carboxylic acid has a hydrocarbon chain length of 9 to 30 carbon atoms, preferably 10 to 20 carbon atoms. Appearance 5 The carboxylic acid is selected from the list consisting of benzoic acid, levulinic acid, D / L-tartaric acid, capric acid, pyruvic acid, citric acid, fumaric acid, D / L-lactic acid, D / L-malic acid, sorbic acid, adipic acid, L-aspartic acid, L-glutamic acid, succinic acid, gluconic acid, linoleic acid, saccharic acid, 3,7-dimethyl-6-octenoic acid, 2-methylpentanoic acid, trans-2-hexenoic acid, caprylic acid, lauric acid, stearic acid, butyric acid, linolenic acid, malonic acid, myristic acid, oleic acid, palmitic acid, phenylacetic acid, propionic acid, valeric acid, decanoic acid, hexanoic acid, and octanoic acid, as described in any one of embodiments 1 to 4. Appearance 6 The aerosol generating substrate according to any one of embodiments 1 to 5, wherein the carboxylic acid-containing alcohol solution comprises only saturated fatty acids such as stearic acid and / or decanoic acid. Appearance 7 The aerosol generating substrate according to any one of embodiments 1 to 6, wherein the alcohol solution preferably contains only stearic acid and decanoic acid in a stearic acid / decanoic acid ratio of 10 / 90, 20 / 80, 30 / 70, 40 / 60, or 50 / 50. Appearance 8 The aerosol generating substrate according to any one of embodiments 1 to 7, wherein the carboxylic acid-containing alcohol solution comprises only stearic acid or decanoic acid. Appearance 9 An aerosol generating substrate according to any one of embodiments 1 to 8, comprising one or more components selected from the group consisting of propylene glycol, 1,3-propanediol, glycerol, water, gum, fragrance, additives, nicotine, and binder. Appearance 10 An aerosol generating substrate according to any one of embodiments 1 to 9, for use in reducing coughing fits caused by inhaling vapor. Appearance 11 An aerosol generating article comprising an aerosol generating substrate as described in any one of the embodiments 1 to 10. Appearance 12 A method for preparing an aerosol generating substrate for vapor absorption, comprising a semi-solid substrate in the form of a foam, a. A step of providing an aerosol generating substrate comprising one or more components selected from the list consisting of propylene glycol, 1,3-propanediol, glycerol, and water. b. A step of providing one or more carboxylic acids to an alcohol solution, and then incorporating the one or more carboxylic acid-containing alcohol solutions into the aerosol generating substrate such that up to about 1% by weight of the total weight percent of the aerosol generating substrate consists of the one or more carboxylic acid-containing alcohol solutions, thereby forming a mixture. c. Optionally, adding one or more components selected from the list consisting of gum, nicotine, flavorings, and binders to the mixture. d. A step of continuously mixing the mixture for a specific period of time and heating the mixture to a temperature slightly above room temperature to produce the semi-solid substrate in the form of a foam. A method that includes this. Appearance 13 The method according to embodiment 12, wherein the carboxylic acid-containing alcohol solution has a concentration of about 0.05 v / v% to about 0.2 v / v%, preferably 0.08 v / v% to 0.15 v / v%, or more preferably about 0.1 v / v%. Appearance 14 The method according to embodiment 12 or 13, wherein the mixture is heated to about 45°C and / or aerated or mixed for about 5 minutes. Appearance 15 An aerosol generating substrate that can be obtained according to the method described in any one of embodiments 12 to 14. [Examples]

[0054] Example 1 The present invention will be described in detail below in relation to its embodiments. However, these embodiments are for illustrative purposes only and do not limit the scope of the present invention.

[0055] [Table 1]

[0056] Table 1 shows the results of an investigation into tobacco mousses (foams) containing alcohol solutions with various weight percentages of carboxylic acids (i.e., stearic acid and decanoic acid). To prepare exemplary foams, the components shown in each column of Table 1 were mixed and combined as follows.

[0057] Equal amounts of stearic acid and decanoic acid were used in all samples, and these carboxylic acids were dissolved in an alcohol solution. Due to their chemical similarity, it is considered that both stearic acid and decanoic acid can be used interchangeably or as substitutes. The concentration of the carboxylic acid-containing alcohol solution is 0.1%.

[0058] Firstly, a solution of propylene glycol, glycerin, carboxylic acid alcohol (containing equal parts stearic acid and decanoic acid), and optionally purified water was frothed and aerated at 45°C for 5-10 minutes, preferably 6 minutes, using a Krups Prep&Cook HP5031 mousse frothing shuffler. When frothing the mousse, the speed must be adjusted so that the volume visibly increases, small bubbles appear, and some remain in the foam. If frothing is too fast, mixing becomes dominant, and the foam structure will collapse, and thus try to return to a liquid state. One option is to start foaming slowly, gradually increase the foaming rate so that the foam begins to develop a lighter, more mousse-like texture, and then reduce the rate by about 10% when it is recognized that the mousse is losing its mousse-like texture and appears to be becoming less aerated. Rapid cooling with ice or cold water is recommended to maintain the foam structure for providing stability. Using the Krups device described above, the best results can be obtained at a rate of 60-200 rpm. Following the above description, those skilled in the art can adapt it to the best of their knowledge.

[0059] In the next step (within 1 minute of the previous step), the gum was added, the mixture was whipped, and aerated at 45°C for 5-10 minutes, preferably 6 minutes, using a Krups Prep&Cook HP5031 mousse whipping shuffler. Then, the tobacco powder was added, the mixture was whipped, and aerated at 45°C for 5-10 minutes, preferably 6 minutes, using the same method. Next, the binder was added, the mixture was whipped again, and aerated at 45°C for 5-10 minutes, preferably 6 minutes, using the same method. Finally, the mixture was placed in an oven at 50°C for 12 hours before being packaged and ready for use.

[0060] Since there are no international standards for the "sensory evaluation" of cough attacks, the scoring for the "sensory evaluation" of cough attacks is performed as follows. The results obtained from Example 1 are shown in Table 2.

[0061] [Table 2]

[0062] To establish a scoring system for the average cough attack, Sample 1 (without carboxylic acid in the consumables) was initially administered to the subjects being evaluated. Each subject inhaled 10 puffs within 3 minutes and rated the degree of throat irritation (100 for very irritated, 60 for somewhat irritated, 30 for slightly irritated, and 0 for no irritation). After Sample 1 was evaluated, Samples 2, 3, 4, and 5 were administered to the subjects in a random order. The procedure was repeated in the same manner as with the control sample (Sample 1). Cough attack scores were rated by the subjects based on their perception of throat irritation. A 60-second (or 120-second) rest period was given before a new sample was administered to the subjects.

[0063] As shown in Table 2, samples 2, 3, 4, and 5, which consisted of 0.2% by weight, 0.5% by weight, 0.8% by weight, and 1.0% by weight carboxylic acid-containing alcohol solutions in the total weight percent mixture of aerosol-generating substrates, respectively, showed lower average coughing attack scores compared to the control sample (sample 1). For example, the total weight of sample 1 (0% by weight stearic acid and decanoic acid) was 500 g.

[0064] Sample 1 (control sample), which did not contain carboxylic acid (fatty acid), recorded the highest average coughing fits score (71.25). Aerosol-generating substrates containing 0.2% to 1.0% by weight of carboxylic acid-containing alcohol solution, based on the total weight percentage of the aerosol-generating substrate, were observed to have significantly lower scores compared to control sample 1, i.e., less than 40, i.e., 36.25, 33, 39, and 37 for samples 2, 3, 4, and 5, respectively. These values ​​represent the very slight throat inflammation or coughing fits observed in samples 2–5, as reported by various subjects.

[0065] Furthermore, in addition to the reduction in cough attacks as assessed by the subjects, as observed in Sample 1 Furthermore, it was reported that samples composed of carboxylic acid-containing alcohols up to 1% by weight, based on the total weight percentage of the aerosol-generating substrate, had no unpleasant taste and exhibited a smoother flavor.

[0066] The minimum amount of carboxylic acid-containing alcohol in the aerosol-generating substrate used in the experiment was 0.2% by weight based on the total weight percentage of the aerosol-generating substrate. However, lower amounts such as 0.1% or 0.05% by weight based on the total weight percentage of the aerosol-generating substrate are thought to be equally effective in suppressing throat inflammation or reducing coughing fits.

[0067] For this purpose, it should be repeatedly mentioned that this remarkable effect of the present invention is observed only on any semi-solid substrate (foam, mousse, gel, mucus) and is not applicable to solid or liquid media.

[0068] The foams of the present invention according to the present invention are not smokeable, i.e., they are applied in a manner that does not heat them to a temperature such that they burn, but at least a portion thereof, particularly at least essentially an aerosol-forming agent and more preferably at least a portion of the tobacco-containing agent and / or inhalable agent, is evaporated. In the foam, at least some portion of the tobacco-containing agent and / or inhalable agent preferably adheres to and / or is absorbed by the foam structure, which is essentially formed by the foam-forming agent and foam stabilizer, and as a result, it can be readily released together with the aerosol-forming agent when heated. Some portion of the tobacco-containing agent and / or inhalable agent may bind to the foam structure, and the tobacco-containing agent and / or inhalable agent may be "extracted" during heating, and as a result, flavor may be released from the tobacco-containing agent and / or inhalable agent together with the aerosol-forming agent. According to certain embodiments, the tobacco-containing agent and / or inhalable agent is arranged and configured to be released together with the aerosol-forming agent when heated, simply by being essentially adsorbed to and / or absorbed into the foam structure. In this regard, the present inventors have shown that a mass loss of foam can be observed, which essentially indicates that the mass of at least the foam-forming agent and foam stabilizer remains unchanged. The structure of the foam is mainly formed by the foam-forming agent, which forms an "encapsulation" for attaching and / or absorbing the aerosol-forming agent and the tobacco component-containing agent and / or inhalable agent, while the foam stabilizer is thought to stabilize the foam in order to maintain its foam form.

Claims

1. an aerosol generating substrate for absorbing vapor, comprising a semi-solid substrate, Up to 1.0% by weight of the total weight percentage of the aerosol generating substrate, it consists of an alcohol solution of a carboxylic acid, and one or more carboxylic acids are dissolved in the alcohol solution. The carboxylic acid is selected from the list consisting of benzoic acid, levulinic acid, D / L-tartaric acid, capric acid, pyruvic acid, citric acid, fumaric acid, D / L-lactic acid, D / L-malic acid, sorbic acid, adipic acid, L-aspartic acid, L-glutamic acid, succinic acid, gluconic acid, linoleic acid, saccharic acid, 3,7-dimethyl-6-octenoic acid, 2-methylpentanoic acid, trans-2-hexenoic acid, caprylic acid, lauric acid, stearic acid, butyric acid, linolenic acid, malonic acid, myristic acid, oleic acid, palmitic acid, phenylacetic acid, propionic acid, valeric acid, decanoic acid, hexanoic acid, and octanoic acid. The aforementioned semi-solid substrate is provided in the form of a foam, and is an aerosol generating substrate.

2. The aerosol generating substrate according to claim 1, comprising 0.2% to 1% by weight of the alcohol solution of the carboxylic acid in the total weight percentage of the aerosol generating substrate.

3. The aerosol generating substrate according to claim 1 or 2, wherein the alcohol solution of the carboxylic acid has a concentration of 0.05 v / v% to 0.2 v / v%.

4. The aerosol generating substrate according to any one of claims 1 to 3, wherein the carboxylic acid has a hydrocarbon chain length of 9 to 30 carbon atoms.

5. The aerosol generating substrate according to any one of claims 1 to 4, wherein the carboxylic acid is stearic acid and / or decanoic acid.

6. The aerosol generating substrate according to any one of claims 1 to 5, wherein the alcohol solution of the carboxylic acid comprises only saturated fatty acids such as stearic acid and / or decanoic acid.

7. The aerosol generating substrate according to any one of claims 1 to 6, wherein the alcohol solution contains only stearic acid and decanoic acid in a weight ratio of 10 / 90, 20 / 80, 30 / 70, 40 / 60, or 50 / 50 stearic acid / decanoic acid.

8. The aerosol generating substrate according to any one of claims 1 to 7, wherein the alcohol solution of the carboxylic acid comprises only stearic acid or decanoic acid.

9. An aerosol generating substrate according to any one of claims 1 to 8, comprising one or more components selected from the group consisting of propylene glycol, 1,3-propanediol, glycerol, water, gum, fragrance, additives, nicotine, and binder.

10. An aerosol generating substrate according to any one of claims 1 to 9, for use in reducing coughing fits caused by inhaling vapor.

11. An aerosol generating article comprising an aerosol generating substrate according to any one of claims 1 to 10.

12. A method for preparing an aerosol generating substrate for vapor absorption, comprising a semi-solid substrate in the form of a foam, a. A step of providing an aerosol generating substrate comprising one or more components selected from the list consisting of propylene glycol, 1,3-propanediol, glycerol, and water. b. A step of providing one or more carboxylic acids to an alcohol solution, and then incorporating the one or more carboxylic acid alcohol solutions into the aerosol generating substrate such that up to 1% by weight of the total weight percentage of the aerosol generating substrate consists of the one or more carboxylic acid alcohol solutions, thereby forming a mixture. d. A step of continuously mixing the mixture for a specific period of time and heating the mixture to 30 to 80°C to produce the semi-solid substrate in the form of a foam. A method that includes this.

13. The method according to claim 12, further comprising the step of adding c. one or more components selected from the list consisting of gum, nicotine, flavorings and binders to the mixture between steps b and d.

14. The method according to claim 12 or 13, wherein the alcoholic solution of the carboxylic acid has a concentration of 0.05 v / v% to 0.2 v / v%.

15. The method according to any one of claims 12 to 14, wherein the mixture is heated at 45°C and / or aerated or mixed for 5 minutes.

16. An aerosol generating substrate that can be obtained according to the method described in any one of claims 12 to 15.

Images