Compounds and methods for reducing SPDEF expression

JP2026094239APending Publication Date: 2026-06-09IONIS PHARMACEUTICALS INC
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Patent Information

Authority / Receiving Office
JP · JP
Patent Type
Applications
Current Assignee / Owner
IONIS PHARMACEUTICALS INC
Filing Date
2026-02-24
Publication Date
2026-06-09

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Abstract

The present invention provides compounds, methods, and pharmaceutical compositions for treating asthma, chronic obstructive pulmonary disease (COPD), cystic fibrosis, pulmonary fibrosis, idiopathic pulmonary fibrosis (IPF), and ulcerative colitis. [Solution] Compounds, methods, and pharmaceutical compositions are provided for reducing the amount of SPDEF RNA in cells or a subject, and in some cases, the amount of SPDEF protein in cells or a subject.
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Claims

[Claim 1] The invention described in the present specification.