Liquid sample dissolution detection device

Abstract

A liquid sample dissolution detection device is provided that realizes mixing of the liquid sample and dissolution liquid and delivery of the mixed liquid to a reagent strip with just one depression action. [Solution] The liquid sample dissolution detection device includes a detection unit, a dissolution unit, and a removable positioning structure. The detection unit includes a detection casing, a sample collection unit, and a detection reagent strip 103. The dissolution unit includes a base 201, a puncturing sleeve 202, a sealing membrane 203, and a bottom bottle 204. The removable positioning structure is installed between the detection unit and the dissolution unit and limits the depth to which the detection unit is inserted into the top opening of the base in the initial state, preventing the puncturing sleeve from breaking the sealing membrane. In the detection state, the removable positioning structure is removed, and the puncturing sleeve is pressed against the insertion portion of the detection casing to break the sealing membrane. The sample collection unit extends into the bottom bottle.

Description

[Technical Field]

[0001] The present invention belongs to the technical field of liquid sample detection, and more particularly to a liquid sample dissolution detection device. [Background technology]

[0002] In conventional technology, if a liquid sample such as saliva is not dissolved with a solvent, some people may not produce enough saliva to detect the sample, which can affect the detection results. If a solvent is used, the saliva and solvent must be mixed and then dripped into the detection device, which is complicated and increases the risk of sample contamination during transportation.

[0003] The patent with publication number CN220194900U, entitled "Integrated Device for Collecting, Preserving, and Detecting Body Fluid Samples," provides a device that integrates dissolution and detection. However, this device requires the installation of a bottle structure to accommodate the reagent strip, resulting in a large overall size. Furthermore, during the detection process, the liquid sample must be squeezed out of the sample absorbent, which tends to leave a large amount of residue on the sample absorbent and result in waste of the liquid sample. Summary of the Invention

[0004] SUMMARY OF THE INVENTION An object of the present invention is to provide a liquid analyte dissolution detection device. The present invention provides a liquid sample dissolution detection device, which includes a sampling detection unit, a dissolution unit, and a removable positioning structure. The sampling detection unit includes a detection casing, a sample collection unit, and a detection reagent strip. The detection reagent strip is attached to the detection casing. The detection casing is divided into a gripping portion and an insertion portion. An opening is provided at the end of the insertion portion. The sample collection unit is fixed to the opening of the detection casing and contacts the sample application area of ​​the detection reagent strip. The dissolution unit includes a base, a piercing sleeve, a sealing membrane, and a bottom bottle. The bottom bottle is attached to the bottom of the base and stores the dissolution solution. A sealing membrane is installed at the top opening of the bottom bottle. The piercing sleeve is slidably connected within the base and has a sharp tip at its end facing the bottom bottle. The removable positioning structure is installed between the sampling detection unit and the dissolution unit and limits the depth to which the sampling detection unit is inserted into the top opening of the base in the initial state, preventing the piercing sleeve from breaking the sealing membrane. In the detection state, the removable positioning structure is removed, and the puncturing sleeve is pressed against the insertion portion of the detection casing to break the sealing membrane, and the specimen collection unit extends into the bottom bottle.

[0005] Preferably, the removable positioning structure is a positioning latch. The positioning latch is installed in the top opening of the base and is integrally molded with the base. The connection between the positioning latch and the base has a fragile structure that can be torn off by external force. A lateral positioning rib is provided on the side of the positioning latch facing the base. In the initial state, the lateral positioning rib provides positioning for the detection casing of the sampling detection unit.

[0006] Preferably, an elastic protrusion is fixed to the inner wall of the base. The piercing sleeve is positioned between the elastic protrusion and the bottom bottle. A first protrusion and a second protrusion are provided on the outer surface of the insertion portion of the detection casing. The first protrusion and the second protrusion are spaced apart from each other from the insertion portion toward the gripping portion. The positions of the first protrusion and the second protrusion correspond to the elastic protrusion on the inner wall of the base. In the initial state, the first protrusion on the detection casing exceeds the elastic protrusion on the inner wall of the base. In the detection state, the second protrusion on the detection casing exceeds the elastic protrusion on the inner wall of the base.

[0007] Preferably, the removable positioning structure uses a protective sleeve that is fitted over the insert of the detection casing, and in the initial state, the top opening of the base of the dissolving unit provides positioning for a stepped surface on the protective sleeve.

[0008] Preferably, an elastic protrusion is fixed to the inner wall of the base. The piercing sleeve is located between the elastic protrusion and the bottom bottle. A second protrusion is provided on the outer surface of the insertion portion of the detection casing. The position of the second protrusion corresponds to the position of the elastic protrusion. In the detection state, the second protrusion on the detection casing exceeds the elastic protrusion on the inner wall of the base.

[0009] Preferably, the elastic projection has guide inclined surfaces on both sides thereof.

[0010] Preferably, the detection casing includes a lower detection plate and an upper detection plate, the opposing sides of the lower detection plate and the upper detection plate are fixed by a plurality of sets of insertion structures, and the sample collection unit has positioning grooves on both sides, and two insertion structures in the opening of the detection casing are respectively fitted into the positioning grooves on both sides of the sample collection unit.

[0011] Preferably, the insertion structure includes an engaging pin and an engaging hole fixed to the upper detection plate and the lower detection plate, respectively, and interlocking with each other.

[0012] Preferably, the sample collection unit is made of a porous net fiber material, which is used to absorb and conduct the liquid sample.

[0013] Preferably, the detection casing is provided with an observation window, the result display area of ​​the detection reagent strip is aligned with the observation window panel, and a transparent observation window panel is fixed to the observation window.

[0014] Preferably, there is a sliding resistance between the piercing sleeve and the base to prevent the piercing sleeve from sliding freely in the absence of an external thrust.

[0015] Preferably, the piercing sleeve is positioned within the base using a locating rib and an upper locating stepped surface.

[0016] Preferably, the detection process is as follows. The sampling and detection unit is removed from the dissolution unit, and the sample collection unit of the sampling and detection unit is used to collect the liquid sample to be tested. With the removable positioning structure removed, the sampling and detection unit is inserted into the dissolving unit and pushed inward, causing the puncturing sleeve in the dissolving unit to slide inward and break the sealing membrane, and the specimen collection unit extends into the bottom bottle. The sample collection unit draws up the dissolving solution in the bottom bottle, and the dissolving solution flows onto the detection reagent strip along with the liquid sample. The detection reagent strip detects the liquid sample that it comes into contact with.

[0017] The beneficial effects of this invention are as follows: 1. This invention integrates the sample collection unit and detection reagent strip into a rectangular detection casing, and combines it with a dissolving unit, allowing the liquid sample and dissolving solution to be mixed and the mixed liquid to be delivered to the reagent strip with just one pressing motion. 2. This device adopts a pen-type structure with a lid, eliminating the need for a bottle structure to accommodate a reagent strip, realizing automatic dissolution and automatic sample addition, while also further miniaturizing the liquid sample dissolution detection device and increasing its compactness. 3. This invention installs a puncturing sleeve inside the dissolving unit, which is pushed out by the detection casing, solving the problem of the sample collection unit being insufficiently strong to break the aluminum foil. At the same time, the structure in which the puncturing sleeve covers the outside of the sample collection unit reduces or prevents the sample collection unit from being crushed, bent, or deformed by external force during the process of breaking the aluminum foil, preventing the liquid sample on the sample collection unit from being squeezed out during the dissolving process. Combined with the process in which the sample collection unit sucks up the dissolving liquid upward, this greatly improves the utilization rate of the liquid sample of this invention. 4. The present invention utilizes a positioning latch or protective sleeve to prevent the sampling detection unit from being excessively inserted into the dissolution unit in the initial state, greatly reducing the possibility of damage to the liquid sample dissolution detection device during transportation. [Brief explanation of the drawings]

[0018] [Figure 1] FIG. 1 is a schematic diagram of the overall structure of the first embodiment of the present invention. [Figure 2] FIG. 2 is an exploded view of the first embodiment of the present invention. [Figure 3] FIG. 3 is a schematic diagram of the relative positions of the sample collection unit and the detection reagent strip in the first embodiment of the present invention. [Figure 4] FIG. 4 is a schematic diagram showing the change of the melting unit before and after the positioning latch is removed in the first embodiment of the present invention. [Figure 5] FIG. 5 is a cross-sectional view of a melting unit according to a first embodiment of the present invention. [Figure 6] FIG. 6 is a cross-sectional view of the sampling and detecting unit according to the first embodiment of the present invention. [Figure 7] FIG. 7 is a schematic diagram of the detection process in the first embodiment of the present invention. [Figure 8] FIG. 8 is a schematic diagram of the overall structure of the second embodiment of the present invention. [Figure 9] FIG. 9 is an exploded view of the second embodiment of the present invention. [Figure 10] FIG. 10 is an exploded view of the third embodiment of the present invention. [Figure 11] FIG. 11 is a structural diagram of the sampling detection unit according to the third embodiment of the present invention. [Figure 12] FIG. 12 is a structural diagram of the puncture sleeve according to the third embodiment of the present invention. [Figure 13] FIG. 13 is a structural diagram of the base according to the third embodiment of the present invention. [Figure 14] FIG. 14 is a schematic diagram of the bottom bottle structure with a sealing membrane according to the third embodiment of the present invention. DETAILED DESCRIPTION OF THE INVENTION

[0019] The invention will now be further explained with reference to the drawings. Example 1 As shown in FIG. 1, the liquid specimen dissolution detection device includes a sampling detection unit 100 and a dissolution unit 200 .

[0020] 2, the sampling detection unit 100 includes a specimen collection unit 105, a lower detection plate 101, an upper detection plate 102, a detection reagent strip 103, and an observation window panel 104. The opposing sides of the lower detection plate 101 and the upper detection plate 102 are fixed by a plurality of sets of insertion structures to form a detection casing. The insertion structures are fixed to the upper detection plate 102 and the lower detection plate 101, respectively, and include interlocking engagement pins and engagement holes.

[0021] As shown in Figures 2 and 3, an opening is provided at the bottom of the detection casing. The sample collection unit 105 is fixed to the opening of the detection casing. The inner end of the sample collection unit 105 overlaps the sample input area of ​​the detection reagent strip 103, allowing the sample to be transferred to the detection reagent strip through the sampling detection unit. The outer end of the sample collection unit 105 protrudes to the outer area of ​​the detection casing. Positioning grooves are provided on both sides of the sample collection unit 105. Two symmetrical insertion structures in the opening of the detection casing are respectively fitted into the positioning grooves on both sides of the sample collection unit 105, thereby realizing the fixation between the sample collection unit 105 and the detection casing.

[0022] The sample collection unit 105 is made of a porous net fiber material and can absorb and conduct liquid samples. In this embodiment, the sample collection unit 105 can collect oral saliva or oral gum residue samples. The observation window panel 104 is made of a transparent material. An observation window is provided on the detection upper plate 102. The observation window panel 104 is fixed to the observation window. The detection reagent strip 103 is fixed in the detection casing, and the result display area of ​​the detection reagent strip 103 is aligned with the observation window panel 104.

[0023] As shown in Figures 4 and 5, the dissolution unit 200 includes a base 201, a piercing sleeve 202, a sealing membrane 203, a bottom bottle 204, and a positioning latch 205. The base 201 is hollow and has an open top and bottom. The bottom bottle 204 is attached to the bottom of the inner cavity of the base 201. A dissolution liquid storage chamber is provided in the bottom bottle 204, which can be filled with dissolution liquid. A sealing membrane 203 is attached to the top opening of the bottom bottle 204, closing the inner cavity of the bottom bottle 204. The piercing sleeve 202 is attached to the center of the inner cavity of the base 201 and is used to slide downward to pierce the sealing membrane 203. The sealing membrane 203 is made of aluminum foil.

[0024] 4, the positioning latch 205 is installed in the top opening of the base 201 and is integrally molded with the base 201. The connection between the positioning latch 205 and the base 201 has a weak structure (it is weaker than other areas of the base 201 and the positioning latch 205) and can be torn off by external force. A lateral positioning rib 206 is provided on the side of the positioning latch 205 facing the base 201. The lateral positioning rib 206 is used to restrict the sampling and detection unit 100 from moving inside the dissolving unit 200.

[0025] As shown in Figures 5 and 6, elastic protrusions 207 are fixed to two opposing side walls of the cavity in the base 201. The detection casing, which is composed of the lower detection plate 101 and the upper detection plate 102, is divided into a gripping portion and an insertion portion. The opening of the detection casing is located at the end of the insertion portion. A first protrusion 106 and a second protrusion 107 are provided on both of the two outer surfaces of the insertion portion of the detection casing. The first protrusion 106 and the second protrusion 107 are arranged with a gap between them from the insertion portion toward the gripping portion. The positions of the first protrusion 106 and the second protrusion 107 correspond to the elastic protrusion 207 on the inner wall of the base.

[0026] The elastic protrusion 207 can be deformed under pressure. Guide inclined surfaces are provided on both sides of the elastic protrusion 207, which can restrain the first protrusion 106 and the second protrusion 107, and at the same time, allow the first protrusion 106 and the second protrusion 107 to pass over the elastic protrusion 207 when the user pushes in or pulls out the sampling detection unit 100. The first protrusion 106 and the second protrusion 107 are interlocked with the elastic protrusion 207 and are used to limit the relative positions of the sampling detection unit 100 and the dissolving unit 200 in two opposing states, respectively.

[0027] The piercing sleeve 202 is slidably connected within the base 201 and is located between the elastic protrusion 207 and the bottom vial 204. A sliding resistance exists between the piercing sleeve 202 and the base 201 to prevent the piercing sleeve 202 from sliding freely when not subjected to an external thrust. The piercing sleeve 202 is installed hollow, and the specimen collection unit 105 passes through the piercing sleeve 202. The end of the piercing sleeve 202 facing the bottom vial 204 is provided with a sharp tip that can break the sealing membrane 203.

[0028] The two relative states of the sampling and detection unit 100 and the dissolving unit 200 are the initial state and the detection state, respectively. In the initial state, the insertion portion of the detection casing is inserted into the top opening of the base 201, and its end contacts the end of the piercing sleeve 202. The connection between the insertion portion of the detection casing and the gripping portion is positioned by the positioning latch 205. The first protrusion 106 on the detection casing exceeds the elastic protrusion 207 on the inner wall of the base. At this time, the elastic protrusion 207 on the inner wall of the base can restrict the first protrusion 106 of the sampling and detection unit from moving outward.

[0029] In the detection state, the positioning latch 205 has already been torn off, and the second protrusion 107 on the detection casing exceeds the elastic protrusion 207 on the inner wall of the base. The piercing sleeve 202 breaks the sealing membrane 203, and the specimen collection unit 105 extends into the bottom bottle 204. At this time, the sampling and detection unit can move further relative to the dissolving unit, and the elastic protrusion 207 on the inner wall of the base can restrict the second protrusion 107 of the sampling and detection unit from moving outward.

[0030] The method for using the liquid specimen dissolution detection device is as follows. Step 1: The sampling and detection unit 100 is removed from the dissolving unit 200, and the sample collection unit 105 of the sampling and detection unit 100 is used to collect the liquid sample to be tested. Step 2: Break the connection between the positioning latch 205 on the melting unit 200 and the base 201, and remove the positioning latch 205. Step 3: As shown in Figure 7, the dissolving unit 200 is set up vertically. The sampling and detecting unit 100 is then inserted into the dissolving unit 200 and pushed inward so that the second protrusion 107 on the detecting casing clears the elastic protrusion 207 on the inner wall of the base 201. The piercing sleeve 202 is pressed against the insertion part of the detecting casing to break the sealing membrane 203, and the specimen collection unit 105 extends into the bottom bottle 204. Step 4: The sample collection unit 105 sucks up the dissolving solution in the bottom bottle 204, and the dissolving solution flows into the sample application area of ​​the detection reagent strip 103 along with the liquid sample. Step 5: Wait for the reaction of the detection reagent strip 103, and observe the detection result through the observation window panel 104 after a predetermined time.

[0031] Example 2 As shown in FIGS. 8 and 9, the liquid specimen dissolution detection device of this embodiment differs from that of the first embodiment in the following respects. 1) The first protrusion 106 is not provided on the insertion portion of the detection casing. The sampling detection unit further includes a protective sleeve 108. The protective sleeve 108 is placed over the outside of the insertion portion of the detection casing and is positioned by the second protrusion 107. The protective sleeve 108 is used to protect the sample collection unit. In the liquid sample dissolution detection device provided in this embodiment, the protective sleeve 108 is removed before sampling the liquid sample to be tested. 2) The positioning latch 205 is not installed in the dissolving unit 200. In the initial state, the stepped surface on the protective sleeve 108 and the end surface of the top opening of the base 201 of the dissolving unit are positioned to prevent the sampling and detection unit 100 from being inserted too far into the dissolving unit 200 and the piercing sleeve 202 from breaking the sealing membrane 203.

[0032] The method for using the liquid specimen dissolution detection device is as follows. Step 1: The sampling and detection unit 100 is removed from the dissolving unit 200, and the protective sleeve 108 is removed. Then, the specimen collection unit 105 of the sampling and detection unit 100 is used to collect the liquid specimen. Step 2: Set the dissolving unit 200 vertically. Insert the sampling detection unit 100 without the protective sleeve 108 back into the dissolving unit 200 and push it inward until the second protrusion 107 on the detection casing clears the elastic protrusion 207 on the inner wall of the base 201. The puncturing sleeve 202 is pressed against the insertion part of the detection casing to break the sealing membrane 203, and the specimen collection unit 105 extends into the bottom bottle 204. Step 3: The sample collection unit 105 sucks up the dissolving solution in the bottom bottle 204, and the dissolving solution flows into the sample application area of ​​the detection reagent strip 103 along with the liquid sample. Step 4: Wait for the reaction of the detection reagent strip 103, and observe the detection result through the observation window panel 104 after a predetermined time.

[0033] Example 3 This embodiment is a liquid specimen dissolution and detection device, and differs from the first embodiment in that the sampling and detection unit 100 and the dissolution unit 200 have different structures. In this embodiment, the sampling detection unit 100 includes a sample collection unit 105, a lower detection plate 101, an upper detection plate 102, a detection reagent strip 103, an observation window panel 104, and a protective sleeve 108. The detection casing, which is composed of the lower detection plate 101 and the upper detection plate 102, does not have the first protrusion 106 and the second protrusion 107 that mate with the base 201. The insertion portion of the detection casing is inserted into the top opening of the protective sleeve 108, and the protective sleeve 108 covers the outside of the sample collection unit 105, providing a protective function and reducing the risk of contamination of the sample collection unit 105. The protective sleeve 108 and the detection casing are axially positioned by aligned positioning surfaces and are detachably fixed by a snap structure 109. The snap structure 109 includes an outer convex fastening point on the detection casing and an engaging groove 2013 on the detection casing.

[0034] In this embodiment, the dissolution unit 200 includes a base 201, a piercing sleeve 202, a sealing membrane 203, and a bottom vial 204, but does not include a positioning latch 205, and further includes a sealing ring 208. The base 201 is not provided with an elastic protrusion 207. The outer bottom of the protective sleeve 108 is inserted into the top opening of the base 201. The protective sleeve 108 and the detection casing are axially positioned by the positioning protrusion on the protective sleeve 108 and the positioning groove on the detection casing, and are detachably fixed by a snap structure 109. The piercing sleeve 202 is located between the sealing membrane 203 and the protective sleeve 108. When the protective sleeve 108 is placed over the detection casing, the detection casing cannot press down on the piercing sleeve 202 to pierce the sealing membrane 203.

[0035] A guide rib 2021 and a positioning boss 2022 are provided on the outside of the piercing sleeve 202. The guide rib 2021 is slidably fitted into a guide groove in the inner cavity of the base 201. A lower positioning rib 2011 and an upper positioning stepped surface 2012 are provided in the center of the inner cavity of the base 201. The positioning boss 2022 is located between the lower positioning rib 2011 and the upper positioning stepped surface 2012. The upper positioning stepped surface 2012 is used to prevent the positioning boss 2022 from moving toward the sampling and detection unit 100. The lower positioning rib 2011 is used to prevent the positioning boss 2022 from moving toward the sealing membrane 203. The positioning boss 2022 of the piercing sleeve 202 can deform and pass over the lower positioning rib 2011 under the action of an external thrust.

[0036] The outer wall of the bottom bottle 204 is provided with an annular groove and an engaging rib 2041. The sealing ring 208 is installed in the annular groove and is located between the bottom bottle 204 and the inner wall of the base 201 to provide a sealing effect. An engaging groove 2013 is provided at the bottom of the inner cavity of the base 201. The engaging rib 2041 of the bottom bottle 204 snaps into the engaging groove 2013 of the base 201 to secure the bottom bottle 204 and the base 201 in place. The sealing ring 208 is located between the engaging rib 2041 and the top opening of the bottom bottle 204.

[0037] The operation process of this embodiment is the same as that of the second embodiment.

Claims

1. A liquid analyte dissolution detection device, comprising: The device includes a sampling and detection unit (100), a lysis unit (200), and a removable positioning structure; The sampling detection unit (100) includes a detection casing, a specimen collection unit (105), and a detection reagent strip (103), the detection reagent strip (103) is attached to the detection casing, the detection casing is divided into a gripping portion and an insertion portion, an opening is provided at the end of the insertion portion, the specimen collection unit (105) is fixed to the opening of the detection casing, and the specimen collection unit (105) is in contact with the sample input area of ​​the detection reagent strip (103); The dissolution unit (200) includes a base (201), a puncture sleeve (202), a sealing membrane (203), and a bottom bottle (204). The bottom bottle (204) is attached to the bottom of the base (201) and stores the dissolution solution. The sealing membrane (203) is installed at the top opening of the bottom bottle (204). The puncture sleeve (202) is slidably connected within the base (201) and has a sharp tip at its end facing the bottom bottle (204). The removable positioning structure is installed between the sampling and detection unit (100) and the dissolving unit (200), and limits the depth of insertion into the top opening of the base (201) of the sampling and detection unit (100) in the initial state, thereby preventing the piercing sleeve (202) from breaking the sealing membrane (203); In the detection state, the removable positioning structure is removed, the puncture sleeve (202) is pressed against the insertion portion of the detection casing to break the sealing membrane (203), and the sample collection unit (105) extends into the bottom bottle (204).

2. The liquid sample dissolution detection device of claim 1, characterized in that the removable positioning structure is a positioning latch (205), which is installed in the top opening of the base (201) and is molded integrally with the base (201), the connection between the positioning latch (205) and the base (201) is a fragile structure that can be torn off by external force, and a lateral positioning rib (206) is provided on the side of the positioning latch (205) facing the base (201), and in the initial state, the lateral positioning rib (206) provides positioning for the detection casing of the sampling detection unit (100).

3. 3. The liquid sample dissolution detection device according to claim 2, wherein an elastic protrusion (207) is fixed to the inner wall of the base (201), the puncture sleeve (202) is positioned between the elastic protrusion (207) and the bottom bottle (204), a first protrusion (106) and a second protrusion (107) are provided on the outer surface of the insertion part of the detection casing, the first protrusion (106) and the second protrusion (107) are arranged at a distance from the insertion part toward the gripping part, the positions of the first protrusion (106) and the second protrusion (107) correspond to the elastic protrusion (207) on the inner wall of the base, and in the initial state, the first protrusion (106) on the detection casing exceeds the elastic protrusion (207) on the inner wall of the base, and in the detection state, the second protrusion (107) on the detection casing exceeds the elastic protrusion (207) on the inner wall of the base.

4. 2. The liquid specimen dissolution detection device according to claim 1, wherein the removable positioning structure uses a protective sleeve (108), and the protective sleeve (108) is fitted over an insert portion of the detection casing.

5. 5. The liquid specimen dissolution detection device according to claim 4, wherein the protective sleeve (108) and the detection casing are detachably fixed by a snap structure (109).

6. 5. The liquid sample dissolution detection device of claim 4, wherein in an initial state, the outer bottom of the protective sleeve (108) is inserted into and fitted with the top opening of the base (201) and positioned by a positioning structure, and the puncture sleeve (202) is positioned between the sealing membrane (203) and the protective sleeve (108).

7. The liquid sample dissolution detection device of claim 4, characterized in that an elastic protrusion (207) is fixed to the inner wall of the base (201), the puncture sleeve (202) is positioned between the elastic protrusion (207) and the bottom bottle (204), a second protrusion (107) is provided on the outer surface of the insertion portion of the detection casing, the position of the second protrusion (107) corresponds to the elastic protrusion (207), and in the detection state, the second protrusion (107) on the detection casing exceeds the elastic protrusion (207) on the inner wall of the base.

8. 8. The liquid specimen dissolution detection device according to claim 3, wherein both sides of said elastic projection (207) are provided with guide inclined surfaces.

9. 2. The liquid sample dissolution detection device according to claim 1, wherein the detection casing includes a lower detection plate (101) and an upper detection plate (102), the opposing sides of the lower detection plate (101) and the upper detection plate (102) are fixed by a plurality of sets of insertion structures, and the sample collection unit (105) has positioning grooves on both sides, and the two insertion structures in the opening of the detection casing respectively fit into the positioning grooves on both sides of the sample collection unit (105).

10. 10. The liquid specimen dissolution detection device according to claim 9, wherein the insertion structure includes an engagement pin and an engagement hole fixed to the upper detection plate (102) and the lower detection plate (101), respectively, and interlocking with each other.

11. 2. The liquid sample dissolution detection device according to claim 1, wherein the sample collection unit (105) is made of a porous net fiber material and is used to absorb and conduct the liquid sample.

12. 2. The liquid sample dissolution detection device according to claim 1, wherein a sliding resistance exists between the puncturing sleeve (202) and the base (201) to prevent the puncturing sleeve (202) from sliding freely in the absence of an external thrust.

13. The liquid sample dissolution detection device of claim 1, characterized in that a positioning boss (2022) is provided on the outside of the puncture sleeve (202), a lower positioning rib (2011) and an upper positioning stepped surface (2012) are provided in the center of the inner cavity of the base (201), the positioning boss (2022) is located between the lower positioning rib (2011) and the upper positioning stepped surface (2012), and the positioning boss (2022) is movable over the lower positioning rib (2011) in a direction approaching the sealing membrane (203) under the action of an external thrust force.

14. 2. The liquid specimen dissolution detection device according to claim 1, wherein a seal ring (208) is provided between the outer wall of the bottom bottle (204) and the inner wall of the base (201).

15. The liquid sample dissolution detection device of claim 1, characterized in that the outer wall of the bottom bottle (204) and the inner cavity of the base (201) form a snap connection by means of interlocking engaging ribs (2041) and engaging grooves (2013), and the engaging ribs (2041) of the bottom bottle (204) are snap-fitted into the engaging grooves (2013) of the base (201).

16. The detection process is as follows: The sampling and detection unit (100) is removed from the dissolving unit (200), and a liquid sample to be tested is collected using the sample collection unit (105) of the sampling and detection unit (100); With the removable positioning structure removed, the sampling and detection unit (100) is inserted into the dissolving unit (200) and pushed inward, causing the sampling and detection unit (100) to slide the puncturing sleeve (202) in the dissolving unit (200) inward, breaking the sealing membrane (203), and the specimen collection unit (105) to extend into the bottom bottle (204); The liquid sample dissolution detection device according to claim 1, characterized in that the sample collection unit (105) draws up the dissolution liquid in the bottom bottle (204), the dissolution liquid flows to the detection reagent strip (103) along with the liquid sample, and the detection reagent strip (103) detects the liquid sample that it comes into contact with.

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