Liquid oral composition and oral foam pump product

The liquid oral composition, with enhanced diffusivity and used in a foam discharge pump container, addresses the challenge of incomplete diffusion in dry mouths by breaking and dispersing effectively within the oral cavity, improving ingredient distribution and safety.

JP7654386B2Active Publication Date: 2025-04-01EARTH CORP
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Patent Information

Application Number
JP2020191746
Authority / Receiving Office
JP · JP
Patent Type
Patents
Current Assignee / Owner
Priority Date
2019-11-27
Filing Date
2020-11-18
Publication Date
2025-04-01
Estimated Expiration
2040-11-18

AI Technical Summary

Technical Problem

Existing liquid oral compositions for foam discharge containers do not effectively diffuse throughout the oral cavity, particularly in dry mouth conditions, leading to incomplete distribution of active ingredients and increased risk of accidental ingestion or aspiration.

Method used

A liquid oral composition with a surfactant, thickener, and water, designed to have a diffusivity of 180% or more, which breaks quickly in the oral cavity and diffuses without saliva or physical stimulation, using a foam discharge pump container with a network structure for optimal dispersion.

Benefits of technology

The composition quickly breaks and diffuses throughout the oral cavity, even in dry conditions, enhancing the distribution of active ingredients and reducing the risk of ingestion or aspiration, while also simplifying toothbrushing without the need for additional water.

✦ Generated by Eureka AI based on patent content.

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Abstract

To provide a liquid oral composition that can break bubbles in an oral cavity and quickly diffuse over the entire oral cavity without saliva or physical stimulus.SOLUTION: A liquid oral composition contains a surfactant, a thickener and water and is charged into a bubble discharging container. The discharged foam of the liquid oral composition has a diffusibility of 180% or more, and it is used in an oral cavity in a dry condition.SELECTED DRAWING: None
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Description

[Technical field]

[0001] The present invention relates to a liquid oral composition, more particularly to a liquid oral composition to be filled into a foaming container.The present invention also relates to an oral foaming pump product filled with the liquid oral composition. [Background technology]

[0002] Conventionally, dentifrice preparations containing oral compositions have mainly been used in the form of powder toothpaste, toothpaste, liquid toothpaste, and the like. Toothpaste has the advantage of being highly shape-retaining on the toothbrush and delivering the formulation into the oral cavity. However, in cases where symptoms of dry mouth are present, such as in elderly people who secrete less saliva, it takes time for the medicine to diffuse throughout the oral cavity, and the medicine may not be fully diffused within the short time it takes to brush the teeth. In addition, while liquid toothpaste solves the problems associated with toothpaste, there is a high risk of accidental ingestion or aspiration in cases where rinsing and spitting are difficult due to decreased oral function.

[0003] Therefore, in recent years, the development of oral compositions for preparations to be used in foam form has been widely studied. For example, Patent Document 1 discloses a liquid oral composition in a foam-dispensing container, which contains a specific amount of anionic surfactant and amphoteric surfactant, a polysaccharide-based natural polymer or nonionic semi-synthetic polymer of a specific viscosity, and water. Patent Document 2 discloses a foam-dispensing composition for oral use that contains a surfactant and a binder that is a combination of a specific polymer compound. Patent Document 3 discloses a foam-dispensing composition for oral use that contains 0.5 to 15% of a surfactant and an aldehyde compound having 7 or 8 carbon atoms in a foam-dispensing container. [Prior art documents] [Patent documents]

[0004] [Patent Document 1] JP 2019-001741 A [Patent Document 2] Japanese Patent Application Publication No. 9-295923 [Patent Document 3] Japanese Patent Application Publication No. 10-114637 Summary of the Invention [Problem to be solved by the invention]

[0005] The liquid oral compositions described in the above Patent Documents 1 and 2 are both foam-retaining and shape-retaining in the oral cavity, and are based on the premise that they can be made into a foam when used and applied for brushing. Furthermore, the foam oral composition described in the above Patent Document 3 improves flavor development, stability of foaming over time, foam retention, and foam texture. Thus, although Patent Documents 1 to 3 have made various investigations into the foam quality of oral compositions, they have not made any specific investigations into the diffusibility within the oral cavity.

[0006] In a foam-like liquid oral composition, the foam's shape retention (foam quality) is an important factor, and if the foam breaks quickly, it will drip when placed on a toothbrush for use. On the other hand, if the foam continues to remain in the oral cavity, there is concern that the active ingredient will not diffuse well into the oral cavity. This is particularly noticeable in people with dry oral cavity, such as the elderly and those with dry mouth.

[0007] The present invention has been made in consideration of the above circumstances, and aims to provide a liquid oral composition that breaks down in the oral cavity and spreads quickly throughout the oral cavity even in the absence of saliva or physical stimulation. [Means for solving the problem]

[0008] As a result of extensive research, the present inventors have found that the above problems can be solved by setting the diffusibility of the discharged foam to a certain value or higher, and have thus completed the present invention. That is, the present invention is as follows. (1) A liquid oral composition comprising a surfactant, a thickener and water, for filling into a foam-ejecting container, wherein the diffusibility of the ejected foam is 180% or more, and the liquid oral composition is used in a dry oral cavity. (2) The liquid oral composition described in (1), characterized in that the liquefaction rate of the ejected foam is 1 to 40%. (3) A foam pump container having a nozzle body that discharges a foam and a discharge flow path through which mixed liquid and gas flow, wherein the nozzle body has a gas-liquid mixing chamber that mixes liquid and gas, and the discharge flow path has a mesh structure, the foam pump container is filled with a liquid oral composition containing a surfactant, a thickener and water as the liquid, and the diffusibility of the discharged foam is 180% or more. Effect of the Invention

[0009] The liquid oral composition of the present invention breaks down bubbles quickly and diffuses well in the oral cavity even when used in a dry oral cavity without the need for saliva or physical stimulation. Since there is no need to add moisture, such as by wetting the toothbrush with water, when brushing teeth, it is easy to use even when someone else brushes the teeth, such as in the case of caregivers.Furthermore, it prevents the various ingredients, such as cleaning agents, disinfectants, and anti-inflammatory agents, from being overly diluted and losing their effectiveness. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0010] [Liquid oral composition] The liquid oral composition of the present invention contains a surfactant, a thickener and water, and is intended to be filled into a foam-ejecting container, and is characterized in that the diffusibility of the ejected foam is 180% or more and it is used in the oral cavity which is in a dry state.

[0011] Here, the dry oral cavity means the oral cavity of a person who secretes little saliva, such as the elderly or a person with dry mouth. Specifically, whether the oral cavity is dry or not can be determined by the chewing gum test or the Saxon test. In the gum test, the oral cavity can be determined to be dry if the amount of saliva that comes out after chewing gum is 10 mL or less in 10 minutes, and in the Saxon test, the oral cavity can be determined to be dry if the weight of saliva contained in gauze is 2 g or less in 2 minutes after chewing gauze.

[0012] In addition, the foam pump product for use in a dry oral cavity according to the present invention is a foam pump container filled with the liquid oral composition, and "for use in a dry oral cavity" is synonymous with being used in an oral cavity that is in a dry state.

[0013] <Surfactant> Surfactants are components that are mainly used as cleaning agents and foaming agents. Specifically, one or more surfactants selected from the group consisting of nonionic surfactants, anionic surfactants, amphoteric surfactants, and cationic surfactants can be used. In this specification, polyoxyethylene may be referred to as POE, and polyoxypropylene may be referred to as POP.

[0014] Examples of nonionic surfactants include POE hydrogenated castor oil, POE alkyl ethers such as POE lauryl ether, POE cetyl ether, and POE stearyl ether, POE fatty acid esters, POE sorbitan fatty acid esters such as POE sorbitan coconut oil fatty acid ester (also called POE coconut oil sorbitan), POE higher alcohol ethers, POE alkyl phenyl ethers, POE phytosterols, POE·POP alkyl ethers such as POE·POP cetyl ether, POE·POP block polymers, POE·POP fatty acid esters, alkyl glycosides, propylene glycol fatty acid esters, glycerin fatty acid esters such as polyglyceryl monolaurate, polyethylene glycol fatty acid esters such as polyethylene glycol monostearate, and sorbitan fatty acid esters. These may be used alone or in combination. Among these, POE hydrogenated castor oil, POE alkyl ether, POE sorbitan fatty acid ester, and alkyl glycoside are preferred because they provide stable formulations when used in combination with cationic fungicides, and POE hydrogenated castor oil, POE lauryl ether, POE coconut oil fatty acid sorbitan, and alkyl glycoside are more preferred.

[0015] Examples of anionic surfactants include POE alkyl ether phosphoric acid or POE alkyl ether phosphate such as POE lauryl ether phosphoric acid or sodium POE lauryl ether phosphate, POE alkyl ether sulfate, alkyl ether carboxylate such as sodium POE lauryl ether acetate, N-acyl amino acid salt such as sodium lauroyl sarcosine or sodium myristoyl sarcosine, N-acyltaurate salt such as sodium lauroyl methyl taurine, alkyl sulfate such as sodium lauryl sulfate or sodium myristyl sulfate, sulfonate such as sodium di(2-ethylhexyl) sulfosuccinate, alkyl phosphate, etc. These may be used alone or in combination. Among these, N-acylamino acid salts, alkyl sulfates, and N-acyltaurate salts are preferred from the viewpoint of excellent foaming power, and sodium lauroyl sarcosine, sodium lauryl sulfate, and sodium lauroyl methyl taurate are more preferred.

[0016] As the amphoteric surfactant, either betaine type or glycine type can be used. Among them, alkyl betaine type or glycine type is preferable, and examples thereof include 2-alkyl-N-carboxymethyl-N-hydroxyethyl imidazolinium betaine, coconut oil fatty acid amidopropyl betaine, sodium lauryl diaminoethyl glycine, lauryl dimethyl amino acetate betaine, etc. These can be used alone or in combination of two or more.

[0017] Examples of cationic surfactants include cetylpyridinium chloride, benzalkonium chloride, benzethonium chloride, alkyltrimethylammonium chloride, dialkyldimethylammonium chloride, POE alkylamine fatty acid amide, etc. These can be used alone or in combination of two or more.

[0018] The surfactant is considered to be a component that contributes to the liquefaction rate of the liquid oral composition. That is, it contributes to the shape retention when the liquid oral composition is discharged in a foam form. By lowering the liquefaction rate, the shape retention of the foam is increased, and dripping when the foam is discharged onto the toothbrush can be suppressed. From the above viewpoint, it is preferable to include a nonionic surfactant as the surfactant, and more specifically, it is more preferable to use at least one selected from the group consisting of POE hydrogenated castor oil, POE lauryl ether, POE coconut oil fatty acid sorbitan, and alkyl glycoside. The content of the surfactant is preferably 0.01 mass% or more in total, more preferably 0.1 mass% or more, and is preferably 10 mass% or less, more preferably 5 mass% or less, and even more preferably 4 mass% or less.

[0019] <Thickener> The thickener is also considered to be a component that contributes to the liquefaction rate of the liquid oral composition. Examples of the thickener include carboxymethylcellulose, hydroxyethylcellulose, hydroxypropylcellulose, xanthan gum, guar gum, carrageenan, gellan gum, pectin, locust bean gum, starch, dextrin, etc., and it is preferable to use at least one selected from the group consisting of carboxymethylcellulose, hydroxyethylcellulose, xanthan gum, and gellan gum. Among them, hydroxyethylcellulose and xanthan gum are more preferable, and hydroxyethylcellulose is even more preferable. The total content is preferably 0.01% by mass or more, more preferably 0.05% by mass or more, and is preferably 1% by mass or less, more preferably 0.5% by mass or less.

[0020] <Other ingredients> In addition to water, which is a solvent, the liquid oral composition of the present invention can contain various other ingredients as long as they do not impair the effects of the invention. For example, alcohols such as ethanol; humectants such as glycerin, propylene glycol, sorbitol, and polyethylene glycol; sweeteners such as stevioside, xylitol, erythritol, sorbitol, sucralose, trehalose, sodium saccharin, and stevia; azulene, azulene sulfonate, β-glycyrrhetinic acid, glycyrrhizinic acid and salts, dihydrocholesterol, epidihydrocholesterol, dl-α-tocopherol acetate, dl-α-tocopherol nicotinate, and ε-aminocaproic acid. anti-inflammatory agents such as phosphate, fluoride, tin fluoride, fluorophosphate, fluoroborate, etc.; phosphate ion sources such as calcium phosphate, hydroxyapatite, etc.; anti-tartar agents such as methoxyethylene maleic anhydride copolymer salt, zinc chloride, organic zinc acid, etc.; collectors such as hinokitiol, allantoin, allantoin chlorohydroxyaluminum, allantoin dihydroxyaluminum, sodium chloride, etc. Stabilizers; preservatives such as parahydroxybenzoic acid esters and sodium benzoate; chelating agents such as ethylenediamine hydroxyethyl triacetate, edetic acid and its salts, glucono delta lactone, gluconic acid, hydroxyethyl ethylenediamine triacetate, pyrophosphate, polyphosphate, metaphosphate, alanine, citric acid and its salts, or tartaric acid and its salts; pH adjusters such as sodium monohydrogen phosphate, sodium dihydrogen phosphate, citric acid, and sodium citrate; peppermint oil, peppermint oil, menthol, carba Fragrance ingredients such as chlorine, eucalyptus oil, eugenol, anethole, cineole, hinokitiol, thymol, pinene, peppermint oil, cinnamon oil, clove oil, eugenol, lemon oil, vanillin, cineole, and eucalyptus oil; herbal medicines such as Phellodendron Bark extract and Angelica acutiloba extract; colorants such as Blue No. 1, Yellow No. 5, Yellow No. 4, Yellow No. 202(1), Red No. 102, Green No. 3, Green No. 201, and sodium copper chlorophyllin; and bactericides such as isopropyl methylphenol and triclosan.

[0021] <Diffusion> The diffusibility of the foam of the liquid oral composition according to the present invention is preferably 180% or more, more preferably 280% or more. In this specification, the foam means a foam discharged from a foam discharge pump container. The foam discharge type pump container includes a nozzle body that discharges a foamed material, and a discharge flow path through which a mixed liquid and gas flow. The nozzle body includes a gas-liquid mixing chamber that mixes the liquid and the gas, and the discharge flow path includes a mesh structure.

[0022] The diffusibility of the foam can also be adjusted by the foam discharge pump container used, for example, by the mesh structure. The mesh size of the mesh structure is preferably 380 mesh or less, more preferably 300 mesh or less, from the viewpoint of obtaining high diffusibility of the foam. On the other hand, from the viewpoint of liquefaction rate, the mesh size is preferably 70 mesh or more, more preferably 100 mesh or more. Note that the mesh refers to the number of warp threads or weft threads per inch (about 25.4 mm), and the number of warp threads and weft threads is the same.

[0023] The mesh structure preferably has an opening of 40 μm or more, more preferably 50 μm or more, in terms of obtaining high diffusibility of the foam. On the other hand, from the viewpoint of the liquefaction rate of the foam, the opening is preferably 200 μm or less, more preferably 150 μm or less. The opening means the distance between warp threads or weft threads.

[0024] In addition, there may be a plurality of mesh structures in the foam discharge pump container. For example, when mesh structures are used at two places, the upper and lower, immediately before foam discharge, the liquid formulation flows through these mesh structures and is discharged as fine bubbles. Here, the upper mesh structure means the one located on the foam discharge port side, and the lower mesh structure means the one located on the container body side. Therefore, the liquid formulation passes through the lower mesh structure and the upper mesh structure in order, and is discharged from the discharge port as foam. In this specification, when a foam-like substance is discharged using a foam discharge pump container having an upper mesh structure with a mesh of 250 mesh and a lower mesh structure with a mesh of 200 mesh, it is expressed as "mesh size #250 / 200". Although the above describes the case where there are two mesh structures, the mesh structures may be used in three or more places.

[0025] In this way, a foam discharge pump container having a plurality of mesh structures may be used, and the meshes and openings may be the same or different. By arranging the mesh structures with a desired gap, the diffusibility and liquefaction rate of the foam made of the liquid oral composition can be adjusted.

[0026] Because the foam produced by ejecting the liquid oral composition has such diffusibility, the bubbles quickly break even in a dry oral cavity, allowing the liquid oral composition to be diffused well throughout the oral cavity without the need for saliva or physical stimulation. Furthermore, when brushing teeth, it is not necessary to add moisture such as by wetting the toothbrush with water. This makes it easy to use for people who need assistance or care, such as infants and the elderly, when someone else brushes their teeth, and is preferable because it prevents aspiration and requires minimal rinsing. Furthermore, it is possible to prevent various ingredients such as cleaning agents, disinfectants, and anti-inflammatory agents from being diluted and losing their effectiveness.

[0027] On the other hand, if the diffusibility is high and the liquefaction rate is too high, the shape retention of the discharged foam is reduced, and the foam discharged onto the toothbrush may drip before being delivered to the oral cavity. Therefore, although there is a preferred upper limit for the diffusibility of the discharged foam, in reality, the value of the diffusibility reaches a plateau. Therefore, instead of the upper limit of the diffusibility, the liquefaction rate described below can be used as an index for dripping.

[0028] As described above, the diffusibility can be adjusted by, for example, the type and content of a thickener, or by a wetting agent such as alcohol, e.g., ethanol, or polyethylene glycol.

[0029] Diffusivity can be confirmed by a test using pig tongue according to the following procedure. First, the pig tongue (processed so that the tongue surface is parallel to the test table by cutting the tongue muscles as necessary) is lightly washed with running water, and then the moisture on the surface of the pig tongue is removed. This moisture removal reproduces a dry mouth condition, and moisture is removed until the moisture content on the pig tongue surface after moisture removal is 15 to 25 when measured with an oral moisture meter Mucus (Life Corporation, product name). A cylindrical tube is placed on the surface of the pig tongue, and the liquid oral composition is discharged into the tube in the form of foam. The contact area between the foam and the pig tongue is fixed by the cylindrical tube, and this is defined as the initial foam property, and the contact area is the initial contact area. Next, the foam is discharged, and after 2 minutes have passed since the tube was removed, the contact area between the foam and the pig tongue is measured and recorded as the contact area after 2 minutes. Diffusion (%) is calculated from the initial contact area and the contact area after 2 minutes using the following formula. Diffusion (%) = (contact area after 2 minutes / initial contact area) x 100

[0030] <Liquification rate> The liquefaction rate of the foam discharged from the liquid oral composition of the present invention is preferably 1% or more, more preferably 2% or more. Also, the liquefaction rate is preferably 40% or less, more preferably 20% or less, and even more preferably 15% or less. By setting the liquefaction rate to 40% or less, the shape retention of the foam outside the oral cavity is improved, and the occurrence of dripping of the discharged foam before it is delivered to the oral cavity can be further suppressed. Also, by setting the liquefaction rate to 1% or more, the foam can be broken in the oral cavity, and the diffusibility can be improved.

[0031] As described above, the liquefaction rate can be adjusted by, for example, the type and content of the surfactant, alcohol such as ethanol, wetting agents such as polyethylene glycol, salts, etc.

[0032] The liquefaction rate can be confirmed by the following procedure. About 4 g of the liquid oral composition is discharged in the form of foam into a 50 mL cone-shaped liquid meter. The weight at this time is the total discharged composition weight. After leaving it to stand for 30 seconds, the liquefied composition is collected with a Pasteur pipette and its weight is measured as the liquefied composition weight. The liquefaction rate (%) is calculated from the total discharged composition weight and the liquefied composition weight using the following formula. Liquefaction rate (%) = (liquefied composition weight / total discharged composition weight) x 100

[0033] When using the above liquid oral composition, it is filled into a foam-dispensing container as a liquid preparation for brushing teeth, and the foam is dispensed onto a toothbrush. The liquid oral composition in the form of a foam has excellent diffusibility in the oral cavity, and is therefore suitable for use by those who have little saliva and whose oral cavity is dry, such as the elderly and those with dry mouth. However, this does not exclude use by those who have a sufficient amount of saliva.

[0034] In addition, since there is no need to moisten the toothbrush with water when brushing teeth, it is possible to prevent aspiration and to minimize the need for rinsing. Therefore, it is also effective for infants, elderly people, and others who require assistance or care when someone else brushes their teeth. Furthermore, since there is no need to add water when using, the various ingredients contained in the liquid oral composition, such as cleaning agents, bactericides, and anti-inflammatory agents, can be prevented from being diluted and their effectiveness reduced.

[0035] [Oral foam pump products] The present invention also relates to an oral foam pump product filled with the above-mentioned liquid oral composition, preferably a dry oral foam pump product. Specifically, the product is characterized in that a liquid oral composition containing a surfactant, a thickener and water is filled in a foam pump container, and the diffusibility of the discharged foam is 180% or more. The foam discharge type pump container includes a nozzle body that discharges a foam and a discharge flow path through which the mixed liquid oral composition and gas flow. The nozzle body includes a gas-liquid mixing chamber that mixes the liquid oral composition and the gas, and the discharge flow path includes a mesh structure. One embodiment of the foam discharge pump container is shown below, but the present invention is not limited to this configuration, and any conventionally known foam discharge pump container can be used.

[0036] The foam-ejection pump container is composed of a container body that is open at the top, and a nozzle body that is removably attached to the opening of the container body and ejects the liquid oral composition filled in the container body as a foam.

[0037] In the nozzle body, the air delivered from the air cylinder and the liquid oral composition delivered from the liquid cylinder meet in the gas-liquid mixing chamber and are mixed. The mixed liquid and gas then flow through the discharge flow path in the nozzle head, and the discharge flow path has a mesh structure.

[0038] The mesh and openings of the mesh structure are as described above, but the mesh structure only needs to be provided in a flow path through which the liquid oral composition and air are mixed and circulate, and the location and number of the mesh structure can be determined arbitrarily. EXAMPLES

[0039] The present invention will be further described below with reference to examples and comparative examples, but the present invention is not limited thereto.

[0040] <Examples 1 to 9 and Comparative Example 1> Various components were mixed according to the formulation shown in Table 1 to prepare liquid oral compositions according to Examples 1 to 9 and Comparative Example 1. The numerical values ​​showing the formulations in Table 1 are expressed in parts by weight. Specifically, the components other than the aqueous hydroxyethyl cellulose solution, concentrated glycerin, and purified water were mixed in a state heated to 50° C. Then, after returning to room temperature, a suitable flavor was added, and the aqueous hydroxyethyl cellulose solution, concentrated glycerin, and purified water were mixed to obtain a liquid oral composition.

[0041] <Diffusion> The diffusibility of the liquid oral composition was evaluated according to the following procedure. After lightly washing the pig tongue (where the tongue muscles were cut as necessary so that the surface of the pig tongue was parallel to the test table) with running water, the moisture on the surface of the pig tongue was removed with Kimtowel (trade name, manufactured by Nippon Paper Crecia Co., Ltd.). This removal of moisture reproduces a dry mouth condition, and the amount of moisture on the surface of the pig tongue after removal was measured with an oral moisture meter Mucus (trade name, manufactured by Life Co., Ltd.) and was found to be 15 to 20, confirming that the moisture had been sufficiently removed. A cylindrical tube was placed on the surface of the pig tongue, and the liquid oral composition was dispensed into the tube in foam form (approximately 0.8 g) using a mesh size of #255 / 200. The contact area between the foam and the pig tongue was 4.86 cm2 due to the cylindrical tube. 2 This is defined as the initial bubble property, and the initial contact area is 4.86 cm 2 It was decided. Next, 2 minutes after the foam was discharged and the tube was removed, the contact area between the foam and the pig tongue (contact area after 2 minutes) was measured from the captured image using image processing software Image J. Then, the diffusivity (%) was calculated from the initial contact area and the contact area after 2 minutes using the following formula. Diffusion (%) = (contact area after 2 minutes) / initial contact area) x 100 The results are shown in Table 1. The evaluation criteria are as follows: ○ or △ indicates a pass. ◯: Diffusivity is 280% or more, which is very good. △: Diffusivity is 180% or more and less than 280%, which is good. ×: Diffusivity is less than 180% and is insufficient.

[0042] <Liquification rate> The liquefaction rate of the liquid oral composition was evaluated using the following procedure. The liquid oral composition was discharged into a 50 mL cone-shaped liquid meter in the form of foam using a mesh size of #255 / 200, at 10 pushes (about 4 g). The weight at this time was taken as the total discharged composition weight. After leaving it to stand for 30 seconds, the liquefied composition was collected with a Pasteur pipette, and its weight was measured as the liquefied composition weight. The liquefaction rate (%) was calculated from the total discharged composition weight and the liquefied composition weight using the following formula. Liquefaction rate (%) = (liquefied composition weight / total discharged composition weight) x 100 The results are shown in Table 1. The evaluation criteria are as follows, with ◯ or △ being preferred. ◯: The liquefaction rate is 20% or less, and the foam has good shape retention. △: The liquefaction rate is more than 20% and not more than 40%, and the shape retention of the foam reaches the standard for use. ×: The liquefaction rate is more than 40%, and the shape retention of the foam does not reach the standard for use.

[0043] [Table 1]

[0044] From the above, it was shown that by making the diffusivity of the liquid oral composition 180% or more, even when the oral cavity is in a dry state, after introducing the liquid oral composition as a foam, the ingredients can be quickly diffused throughout the oral cavity without the addition of moisture, saliva, physical stimulation, etc. It was also shown that the above effect can be obtained regardless of the type of surfactant.

Claims

1. A liquid oral composition comprising a surfactant, a thickener and water, for filling into a foam dispenser, The content of the surfactant is 4% by mass or less, The diffusibility of the discharged foam is 180% or more, A liquid oral composition characterized by being used in a dry oral cavity.

2. A liquid oral composition as described in claim 1, characterized in that the liquefaction rate of the ejected foam is 1 to 40%.

3. A foam discharge type pump container comprising a nozzle body for discharging a foamed material and a discharge flow path through which a mixed liquid and gas flow, the nozzle body comprising a gas-liquid mixing chamber for mixing the liquid and the gas, and the discharge flow path comprising a mesh structure. The liquid is a liquid oral composition containing a surfactant, a thickener and water, The content of the surfactant in the liquid oral composition is 4% by mass or less, A foam-ejecting pump product for use in a dry oral cavity, characterized in that the diffusibility of the ejected foam is 180% or more.

Citation Information

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