Lamellar gel-containing composition, emulsion composition, and skin external preparation composition

Abstract

This lamellar gel phase-containing composition contains a first nonionic surfactant having a hydrophobic moiety on both sides of a hydrophilic moiety. The first nonionic surfactant forms at least a portion of the lamellar gel phase. The content of higher aliphatic alcohol or higher fatty acid is no more than 1 mass% of the composition mass.

Description

Related Application

[0001] This invention is based on the claim of priority of Japanese Patent Application: Japanese Patent Application No. 2020-068416 (filed on April 6, 2020), and the entire description of the application is incorporated herein by reference.

Technical Field

[0002] The present disclosure relates to a composition having a lamellar gel phase. The present disclosure relates to an emulsion composition using a lamellar gel phase. Further, the present disclosure relates to a composition for external use on the skin containing a lamellar gel phase.

Background Art

[0003] Conventionally, for the purpose of maintaining the emulsion stability of external preparations for the skin such as cosmetics, quasi-drugs, and pharmaceuticals, lamellar gel (α gel) formed by higher aliphatic alcohols and higher fatty acids and a hydrophilic surfactant has been used in lamellar gel-containing external preparations for the skin (see, for example, Patent Document 1 and Non-Patent Document 1).

[0004] Patent Document 1 discloses a composition for forming an α gel, which contains (A) 25 to 50% by mass of one or more higher aliphatic alcohols having 16 or more carbon atoms and / or higher fatty acids, (B) 40 to 70% by mass of a polyoxyethylene sterol ether represented by a specific formula, and (C) 5 to 20% by mass of a polyoxyethylene dialkyl ester and / or ether represented by a specific formula, and an α gel is formed by adding water.

Prior Art Documents

Patent Documents

[0005]

Patent Document 1

Non-Patent Document 1

Summary of the Invention

Problems to be Solved by the Invention

[0006] The following analysis is provided from the perspective of the present disclosure.

[0007] A lamellar gel-containing composition containing a higher aliphatic alcohol or a higher fatty acid as described in Patent Document 1 causes a sticky feeling during application when applied to the skin, and the user cannot obtain a refreshing feeling of use. Further, such a lamellar gel-containing composition has problems such as higher alcohols and higher fatty acids being likely to precipitate as crystals over time (see, for example, Non-Patent Document 1).

[0008] The α-gel formed of a higher aliphatic alcohol as described in Patent Document 1 generally has high solubility in highly polar oily components. Therefore, the α-gel-forming composition as described in Patent Document 1 is not suitable as an emulsifier for highly polar oily components.

[0009] Therefore, there is a demand for a composition that provides a refreshing feeling of use and also has high emulsification stability with respect to highly polar oily components.

Means for Solving the Problems

[0010] According to a first aspect of the present disclosure, a composition having a lamellar gel phase is provided. The composition contains a first nonionic surfactant represented by the formula shown in Chemical Formula 1 below. The first nonionic Property surfactant constitutes at least a part of the lamellar gel phase. The content of the higher aliphatic alcohol or the higher fatty acid is 1% by mass or less with respect to the mass of the composition.

[0011] In the formula shown in Chemical Formula 1, R 1 is a linear acyl group or a linear alkyl group having 16 to 24 carbon atoms. R 2 is an alkylene group having 2 to 4 carbon atoms. R 3 is a linear acyl group or a linear alkyl group having 16 to 24 carbon atoms. k represents an integer of 4 to 15.

[0012]

Chem.

[0013] According to a second aspect of the present disclosure, an emulsion composition is provided that includes the composition according to the first aspect, an oily component, and water. The oily component or water is emulsified in a lamellar gel phase.

[0014] According to a third aspect of the present disclosure, a topical skin composition is provided that contains the composition according to the first aspect and / or the second aspect.

Advantages of the Invention

[0015] The composition of the present disclosure can provide a refreshing feeling when applied to the skin.

[0016] The lamellar gel phase of the present disclosure has low solubility in polar oils. According to the lamellar gel-containing composition of the present disclosure, even a polar oil can be stably emulsified.

Brief Description of the Drawings

[0017]

Figure 1

Figure 2

Figure 3

Figure 4

Figure 5

Figure 6

Figure 7

Figure 8

Mode for Carrying Out the Invention

[0018] Preferred forms of each of the above viewpoints are described below.

[0019] According to the preferred form of the first viewpoint, the first nonionic surfactant is polyethylene glycol distearate in which k shown in the formula of Chemical Formula 1 is 4 to 8.

[0020] According to the preferred form of the first viewpoint, the first nonionic surfactant is 0.1% by mass to 40% by mass based on the mass of the composition.

[0021] According to the preferred form of the first viewpoint, the composition further contains a second nonionic surfactant having an HLB of 7 to 15 and water. The first nonionic surfactant, the second nonionic surfactant, and water constitute at least a part of the lamellar gel phase.

[0022] According to the preferred form of the first viewpoint, the second nonionic surfactant is at least one selected from the group of compounds represented by the formulas shown in Chemical Formulas 2 to 5 below.

[0023] In the formula shown in Chemical Formula 2, R 4 is a linear acyl group or a linear alkyl group having 16 to 24 carbon atoms. R 5 is an alkylene group having 2 to 4 carbon atoms. l represents an integer of 5 to 20.

[0024]

Chemical Formula

[0025] In the formula shown in Chemical Formula 3, R 6 , R 10 and R 14 are each an alkylene group having 2 to 4 carbon atoms. R 7 , R 11 and R 15 are each an alkylene group having 8 to 12 carbon atoms. R 8 , R12 and R 16 are each an alkyl group having 4 to 8 carbon atoms. R 9 , R 13 and R 17 are each a polymer of 12-hydroxystearic acid or a polymer of alkylene polyol. m, n, and o are each natural numbers. The sum of m, n, and o is 10 to 60.

[0026]

Chemical formula

[0027] In the formula shown in Chemical formula 4, R 18 is a linear acyl group or a linear alkyl group having 16 to 24 carbon atoms. R 19 and R 20 are each an alkylene group having 2 to 4 carbon atoms. p and q are each natural numbers. The sum of p and q is 5 to 20.

[0028]

Chemical formula

[0029] In the formula shown in Chemical formula 5, R 21 , R 22 , R 23 and R 25 are each an alkylene group having 2 to 4 carbon atoms. r, s, t, and u are each natural numbers. The sum of r, s, t, and u is 5 to 30. R 24 is a linear acyl group or a linear alkyl group having 16 to 24 carbon atoms.

[0030]

Chemical formula

[0031] According to the preferred form of the first aspect, the lamellar gel phase has a higher eutectic point and melting enthalpy than the lamellar gel phase formed by any one of the second nonionic surfactants shown in the formulas of Chemical formulas 3 to 5.

[0032] According to a preferred embodiment of the above first viewpoint, with respect to 1 part by mass of the first nonionic surfactant, the second nonionic surfactant is 0.5 part by mass to 6 parts by mass.

[0033] In the following description, PEG is an abbreviation for polyethylene glycol, POE is an abbreviation for polyoxyethylene, and POP is an abbreviation for polyoxypropylene. The numbers in parentheses after PEG, POE, or POP represent the average number of added moles of the PEG, POE group, or POP group in the compound.

[0034] In the present disclosure, "substantial amount" means an amount by which the action and effect due to the addition of the compound can occur.

[0035] A lamellar gel-containing composition according to a first embodiment of the present disclosure will be described. The composition according to the first embodiment contains a lamellar gel phase. The composition contains a first nonionic surfactant. The nonionic surfactant constitutes at least a part of the lamellar gel phase.

[0036] In the present disclosure, the "lamellar gel phase" refers to a gel-like substance formed by an aggregate composed of a lamellar bilayer formed by a hydrophilic surfactant in the coexistence of water. However, generally, an aggregate formed by a higher aliphatic alcohol and a hydrophilic surfactant in water and having an α-type structure (by Shoji Fukushima, "Physical Chemistry of Cetyl Alcohol", Fragrance Journal Co., Ltd.) is called a lamellar gel.

[0037] The formation of the lamellar gel phase can be confirmed by analyzing the X-ray scattering pattern. For example, when a plurality of peaks corresponding to the long-spacing are obtained in the small-angle region and a sharp single peak is obtained in the wide-angle region (scattering vector q = 1.5 nm -1 ), it can be determined that the lamellar gel phase is formed.

[0038] [First nonionic surfactant] The lamellar gel-containing composition of the present disclosure contains a first nonionic surfactant that is considered to constitute at least a part of the lamellar gel phase. The first nonionic surfactant is preferably a nonionic surfactant having hydrophobic parts on both sides of the hydrophilic part. For example, the first nonionic surfactant can be a nonionic surfactant having the structure shown in Chemical Formula 6 below. In the formula shown in Chemical Formula 6, R 1 is a linear acyl group or a linear alkyl group having 16 to 24 carbon atoms. R 2 is an alkylene group having 2 to 4 carbon atoms. R 3 is a linear acyl group or a linear alkyl group having 16 to 24 carbon atoms. k is an integer of 4 to 15.

[0039] [Chemical Formula]

[0040] Examples of the first nonionic surfactant include polyoxyethylene (4 mol) distearic acid (e.g., Emalex 200DIS manufactured by Nippon Emulsion Co., Ltd.), polyoxyethylene (6 mol) distearic acid (e.g., Emalex 300DIS manufactured by Nippon Emulsion Co., Ltd.), polyoxyethylene (8 mol) distearic acid (e.g., Emalex 400DIS manufactured by Nippon Emulsion Co., Ltd.), polyoxyethylene (12 mol) distearic acid (e.g., Emalex 600DIS manufactured by Nippon Emulsion Co., Ltd.), stearyl stearate-4 (e.g., Emalex SWS-4 manufactured by Nippon Emulsion Co., Ltd.), stearyl stearate-6 (e.g., Emalex SWS-6 manufactured by Nippon Emulsion Co., Ltd.), stearyl stearate-9 (e.g., Emalex SWS-9 manufactured by Nippon Emulsion Co., Ltd.), polyoxyethylene (8 mol) dibehenyl ether, and the like. The bonding mode of the polyoxyethylene chain and the alkyl group may be an ester, an ether, or both may be included.

[0041] The content rate of the first nonionic surfactant is preferably 0.05 mass% or more with respect to the mass of the composition. The first nonionic surfactant can be 0.1 mass% or more, 0.5 mass% or more, 1 mass% or more, 2 mass% or more, 5 mass% or more, 10 mass% or more, 15 mass% or more, 20 mass% or more, or 25 mass% or more. When the content rate of the first nonionic surfactant is less than 0.05 mass%, it becomes difficult to form a gel that is stable with respect to the polar oil. The content rate of the first nonionic surfactant is preferably 40 mass% or less with respect to the mass of the composition. The first nonionic surfactant can be 30 mass% or less, 25 mass% or less, 20 mass% or less, 15 mass% or less, 10 mass% or less, or 5 mass% or less. When the content rate of the first surfactant exceeds 40 mass%, the viscosity becomes extremely high and the feel in use deteriorates.

[0042] The lamellar gel-containing composition of the present disclosure according to the first embodiment can further contain a second nonionic surfactant. The second nonionic surfactant is considered to constitute at least a part of the lamellar gel phase together with the first nonionic surfactant. The second nonionic surfactant preferably has an HLB of 7 or more. The second nonionic surfactant preferably has an HLB of 15 or less.

[0043] The second nonionic surfactant can be at least one nonionic surfactant selected from the group consisting of compounds represented by the following Chemical Formulas 7 to 10. The second nonionic surfactant may be a combination of a plurality of types.

[0044] In the formula shown in Chemical Formula 7, R 4 is a linear acyl group or a linear alkyl group having 16 to 24 carbon atoms. R 5 is an alkylene group having 2 to 4 carbon atoms. l is an integer of 5 to 20.

[0045]

Chemical Formula

[0046] Examples of the second nonionic surfactant shown in Chemical Formula 7 include polyoxyethylene (20 moles) behenyl ether (e.g., Nikkol BB-20 manufactured by Nikko Chemicals Co., Ltd.), polyoxyethylene (10 moles) stearyl ether (e.g., Emalex 610 manufactured by Nippon Emulsion Co., Ltd.), polyoxyethylene (7 moles) cetyl ether (e.g., Emalex 107 manufactured by Nippon Emulsion Co., Ltd.), and the like.

[0047] In the formula shown in Chemical Formula 8, R 6 , R 10 and R 14 are each an alkylene group having 2 to 4 carbon atoms. R 7 , R 11 and R 15 are each an alkylene group having 8 to 12 carbon atoms. R 8 , R 12 and R 16 are each an alkyl group having 4 to 8 carbon atoms. R 9 , R 13 and R 17 are each a polymer of 12-hydroxystearic acid or a polymer of alkylene polyol. The degree of polymerization of the polymer of 12-hydroxystearic acid or the polymer of alkylene polyol can be, for example, 1 to 3. m, n, and o are each natural numbers. The sum of m, n, and o is 10 to 60.

[0048]

Chemical Formula

[0049] Examples of the second nonionic surfactant shown in Chemical Formula 8 include polyoxyethylene (20 moles) hydrogenated castor oil fatty acid glyceryl (e.g., Nikkol HCO-20 manufactured by Nikko Chemicals Co., Ltd.), polyoxyethylene (60 moles) hydrogenated castor oil fatty acid glyceryl (e.g., Nikkol HCO-60 manufactured by Nikko Chemicals Co., Ltd.), and the like.

[0050] In the formula shown in Chemical Formula 9, R 18is a linear acyl group or a linear alkyl group having 16 to 24 carbon atoms. R 19 and R 20 are each an alkylene group having 2 to 4 carbon atoms. p and q are each a natural number. The sum of p and q is 5 to 20.

[0051] [Chemical formula]

[0052] Examples of the second nonionic surfactant shown in Chemical formula 9 include polyoxyethylene (5 moles) glyceryl monostearate (for example, Emalex GM-5 manufactured by Nippon Emulsion Co., Ltd.), polyoxyethylene (10 moles) glyceryl monostearate (for example, Emalex GM-10 manufactured by Nippon Emulsion Co., Ltd.), and the like.

[0053] In the formula shown in Chemical formula 10, R 21 , R 22 , R 23 and R 25 are each an alkylene group having 2 to 4 carbon atoms. r, s, t, and u are each a natural number. The sum of r, s, t, and u is 5 to 30. R 24 is a linear acyl group or a linear alkyl group having 16 to 24 carbon atoms.

[0054] [Chemical formula]

[0055] Examples of the second nonionic surfactant shown in Chemical formula 10 include polyoxyethylene (20 moles) sorbitan monostearate (for example, Nikkol TS-10V manufactured by Nikko Chemicals Co., Ltd.), and the like.

[0056] The content rate of the second nonionic surfactant is preferably 0.05% by mass or more with respect to the mass of the composition. The second nonionic surfactant can be 0.1% by mass or more, 0.5% by mass or more, 1% by mass or more, 2% by mass or more, 5% by mass or more, 10% by mass or more, 15% by mass or more, 20% by mass or more, or 25% by mass or more. If the content rate of the second nonionic surfactant is less than 0.05% by mass, it becomes difficult to form a lamellar gel. The content rate of the second nonionic surfactant is preferably 60% by mass or less with respect to the mass of the composition. The second nonionic surfactant can be 50% by mass or less, 40% by mass or less, 30% by mass or less, 25% by mass or less, 20% by mass or less, 15% by mass or less, 10% by mass or less, or 5% by mass or less.

[0057] The mass ratio of the first nonionic surfactant to the second nonionic surfactant is preferably such that the second nonionic surfactant is 0.5 part by mass or more with respect to 1 part by mass of the first nonionic surfactant. The second nonionic surfactant can be 1 part by mass or more, 1.5 parts by mass or more, 2 parts by mass or more, 2.5 parts by mass or more, or 3 parts by mass or more with respect to 1 part by mass of the first nonionic surfactant. The mass ratio of the first nonionic surfactant to the second nonionic surfactant is preferably such that the second nonionic surfactant is 5 parts by mass or less with respect to 1 part by mass of the first nonionic surfactant. The second nonionic surfactant can be 4 parts by mass or less, 3 parts by mass or less, or 2 parts by mass or less with respect to 1 part by mass of the first nonionic surfactant. If the second nonionic surfactant exceeds 5 parts by mass with respect to 1 part by mass of the first nonionic surfactant, it becomes difficult to form a lamellar gel having high stability with respect to the polar oil.

[0058] [Higher aliphatic alcohol·Higher fatty acid] In the composition of the present disclosure, a lamellar gel phase can be constructed with only nonionic surfactants. In the composition of the present disclosure, the content of higher aliphatic alcohols or higher fatty acids having 16 or more carbon atoms constituting the lamellar gel phase is preferably 1% by mass or less based on the mass of the composition. The composition of the present disclosure can also substantially contain no higher aliphatic alcohols or higher fatty acids having 16 or more carbon atoms. When the content of the higher aliphatic alcohol or higher fatty acid constituting the lamellar gel phase exceeds 1% by mass, the user feels stickiness when applying it to the skin.

[0059] [Water] The lamellar gel-containing composition of the present disclosure can further contain water. As the water, water used in cosmetics, quasi-drugs, etc. can be used. For example, purified water, ion-exchanged water, tap water, etc. can be used.

[0060] The water content can be 10% by mass or more, 15% by mass or more, 20% by mass or more, 25% by mass or more, 30% by mass or more, 35% by mass or more, or 40% by mass or more based on the mass of the composition. The water content can be 90% by mass or less, 80% by mass or less, 70% by mass or less, 60% by mass or less, 50% by mass or less, 40% by mass or less, 30% by mass or less, 25% by mass or less, or 20% by mass or less based on the mass of the composition.

[0061] The manufacturing method of the lamellar gel-containing composition according to the first embodiment of the present disclosure will be described. The method for manufacturing a lamellar gel composition can include, for example, a step of heating and melting the above-described nonionic surfactant, and a step of adding water to the melted nonionic surfactant and stirring. The nonionic surfactant can be melted, for example, at 70°C to 80°C. The water to be added is preferably heated to about the same degree as the nonionic Property surfactant (for example, 70°C to 80°C). The lamellar gel phase can be obtained by cooling after adding water. When the nonionic surfactant is a mixture, for example, a mixture of the nonionic surfactant shown in Chemical Formula 6 and the nonionic surfactants shown in Chemical Formulas 7 to 10 can be heated and melted.

[0062] The lamellar gel phase of the present disclosure can be constructed with nonionic surfactants without using higher aliphatic alcohols or higher fatty acids. Thereby, when the lamellar gel phase is applied to the skin, the user can obtain a refreshing feeling of use without feeling stickiness like that of the lamellar gel phase using higher aliphatic alcohols or higher fatty acids. In particular, since it is considered that a large amount of aqueous components are not incorporated between the lamellae, the skin affinity during application can be improved quickly, and the skin moisturizing effect is excellent after application.

[0063] The composition of the present disclosure can have a lamellar gel phase configured as a one-phase self-assembled body. In the composition of the present disclosure, the formation of a two-phase mixture of the lamellar gel phase and crystals can be suppressed. Thereby, in the composition of the present disclosure, it is possible to suppress the occurrence of stability problems such as crystal precipitation and viscosity increase.

[0064] The lamellar gel phase of the present disclosure formed with the nonionic surfactant shown in Chemical Formula 6 and the nonionic surfactants shown in Chemical Formulas 7 to 10 has a higher eutectic point and melting enthalpy than the lamellar gel phase formed with the nonionic surfactant shown in Chemical Formulas 7 to 10 alone. By having a high eutectic point and melting point enthalpy, the stability against high temperatures can be increased.

[0065] The emulsified composition according to the second embodiment of the present disclosure will be described. The emulsified composition of the present disclosure contains the lamellar gel phase-containing composition according to the first embodiment, an oily component, and water. The emulsified composition can be an oil-in-water type emulsified composition in which water is emulsified with the lamellar gel phase. The emulsified composition can be a water-in-oil type composition in which the oily component is emulsified with the lamellar gel phase.

[0066] The oily component is not particularly limited, and for example, liquid oils and fats, solid oils and fats, waxes, hydrocarbon oils, higher fatty acids, higher alcohols, synthetic ester oils, silicone oils, etc. can be appropriately blended.

[0067] Examples of liquid oils include avocado oil, camellia oil, turtle oil, macadamia nut oil, corn oil, mink oil, olive oil, rapeseed oil, egg yolk oil, sesame oil, persic oil, wheat germ oil, sasanqua oil, castor oil, linseed oil, safflower oil, cottonseed oil, eno oil, soybean oil, peanut oil, tea seed oil, kaya oil, rice bran oil, sinagiri oil, Japanese cedar oil, jojoba oil, germ oil, triglycerin, etc.

[0068] Examples of solid fats include cocoa butter, coconut oil, horse fat, hydrogenated coconut oil, palm oil, beef tallow, mutton fat, hydrogenated beef tallow, palm kernel oil, lard, beef bone fat, candelilla wax, hardened oil, beef foot fat, candelilla wax, hydrogenated castor oil, etc.

[0069] Examples of waxes include beeswax, candelilla wax, cotton wax, carnauba wax, barberry wax, ibota wax, whale wax, montan wax, nuka wax, lanolin, kapok wax, lanolin acetate, liquid lanolin, sugarcane wax, isopropyl lanolin fatty acid, hexyl laurate, reduced lanolin, jojoba wax, hard lanolin, shellac wax, POE lanolin alcohol ether, POE lanolin alcohol acetate, POE cholesterol ether, polyethylene glycol lanolin fatty acid, POE hydrogenated lanolin alcohol ether, etc.

[0070] Examples of hydrocarbon oils include liquid paraffin, ozokerite, squalane, pristane, paraffin, ceresin, squalene, petrolatum, microcrystalline wax, etc.

[0071] Examples of higher fatty acids include lauric acid, myristic acid, palmitic acid, stearic acid, behenic acid, oleic acid, undecylenic acid, toleic acid, isostearic acid, linoleic acid, linolenic acid, eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), etc.

[0072] As the higher alcohol, for example, linear alcohols (e.g., lauryl alcohol, cetyl alcohol, stearyl alcohol, behenyl alcohol, myristyl alcohol, oleyl alcohol, cetostearyl alcohol, etc.); branched-chain alcohols (e.g., monostearyl glycerin ether (batyl alcohol), 2-decyltetradecynol, lanolin alcohol, cholesterol, phytosterol, hexyl dodecanol, isostearyl alcohol, octyldodecanol, etc.) and the like can be used.

[0073] Examples of synthetic ester oils include isopropyl myristate, cetyl octanoate, octyldodecyl myristate, isopropyl palmitate, butyl stearate, hexyl laurate, myristyl myristate, decyl oleate, hexyldecyl dimethyloctanoate, cetyl lactate, myristyl lactate, lanolin acetate, isocetyl stearate, isocetyl isostearate, cholesteryl 12 - hydroxystearate, ethylene glycol di - 2 - ethylhexanoate, dipentaerythritol fatty acid ester, N - alkyl glycol monoisostearate, neopentyl glycol dicaprate, diisostearyl malate, glycerin di - 2 - heptylundecanoate, trimethylolpropane tri - 2 - ethylhexanoate, trimethylolpropane triisostearate, pentaerythritol tetra - 2 - ethylhexanoate, glycerin tri - 2 - ethylhexanoate, glycerin trioctanoate, glycerin triisopalmitate, trimethylolpropane triisostearate, cetyl 2 - ethylhexanoate, 2 - ethylhexyl palmitate, glycerin trimyristate, glyceride di - 2 - heptylundecanoate, methyl ester of castor oil fatty acid, oleyl oleate, acetoglyceride, 2 - heptylundecyl palmitate, diisobutyl adipate, 2 - octyldodecyl N - lauroyl - L - glutamate ester, di - 2 - heptylundecyl adipate, ethyl laurate, di - 2 - ethylhexyl sebacate, 2 - hexyldecyl myristate, 2 - hexyldecyl palmitate, 2 - hexyldecyl adipate, diisopropyl sebacate, 2 - ethylhexyl succinate, triethyl citrate, and the like.

[0074] Examples of silicone oils include silicone compounds such as dimethylpolysiloxane, methylhydrogenpolysiloxane, methylphenylpolysiloxane, stearoxymethylpolysiloxane, polyether-modified organopolysiloxane, fluoroalkyl·polyoxyalkylene copolymer-modified organopolysiloxane, alkyl-modified organopolysiloxane, end-modified organopolysiloxane, fluorine-modified organopolysiloxane, amino-modified organopolysiloxane, silicone gel, acrylic silicone, trimethylsiloxysilicic acid, silicone RTV rubber, cyclopentasiloxane, etc.

[0075] The content of the oily component is preferably 0.05% by mass or more based on the mass of the emulsified composition. The oily component can be, for example, 1% by mass or more, 5% by mass or more, 10% by mass or more, 15% by mass or more, 20% by mass or more, 25% by mass or more, or 30% by mass or more. If the oily component is less than 0.05% by mass, the effect when used as a skin external preparation will be low. The oily component can be, for example, 45% by mass or less, 40% by mass or less, 35% by mass or less, 30% by mass or less, 25% by mass or less, 20% by mass or less, or 15% by mass or less. The content of the oily component is preferably 50% by mass or less based on the mass of the emulsified composition. If the oily component exceeds 50% by mass, the usability on the skin will deteriorate.

[0076] In the second embodiment, the higher aliphatic alcohol or higher fatty acid can be contained as an oily component in an amount of 1% by mass or more.

[0077] Regarding the content rates of the first nonionic surfactant, the second nonionic surfactant, and water in the second embodiment, they can be calculated from the content rates of the lamellar gel phase-containing composition described later. Also, regarding the content rates of the first nonionic surfactant, the second nonionic surfactant, and water in the second embodiment, the descriptions in the above-mentioned first embodiment can be incorporated herein, and the explanations here are omitted.

[0078] A method for producing an emulsified composition according to a second embodiment of the present disclosure will be described. As a first aspect, a method for producing an oil-in-water composition can include, for example, a step of emulsifying an oily component in a lamellar gel phase and a step of adding an aqueous component after emulsification. The step of emulsifying the oily component can include, for example, a step of preparing a solution in which a first nonionic surfactant and a second nonionic surfactant are dissolved in a polyhydric alcohol (e.g., dipropylene glycol, 1,3-butylene glycol), and a step of emulsifying while adding the oily component to the solution. For example, the emulsified composition of the present disclosure can be produced using a non-aqueous emulsification method (D-phase emulsification method). By using the non-aqueous emulsification method, emulsified particles can be made finer.

[0079] As a second aspect, a method for producing an emulsified composition of the present disclosure can include a step of producing a composition according to the first embodiment and a step of emulsifying an oily component or water in the lamellar gel phase in the composition.

[0080] In the emulsified composition according to the second embodiment, the lamellar gel phase-containing composition according to the first embodiment can be blended in any amount. For example, in the emulsified composition, the lamellar gel-containing composition can be blended so that the total amount of the nonionic surfactant forming the lamellar gel phase is 0.1% by mass or more based on the mass of the emulsified composition. The lamellar gel phase-containing composition can be blended so that the total amount of the nonionic surfactant forming the lamellar gel phase is 20% by mass or less based on the mass of the emulsified composition.

[0081] The emulsified composition of the present disclosure has higher stability and faster skin affinity than an emulsion emulsified in a lamellar gel phase using a higher aliphatic alcohol or a higher fatty acid.

[0082] The lamellar gel phase of the present disclosure has low solubility in highly polar oily components. Thereby, it is possible to emulsify highly polar oils that cannot be emulsified in a lamellar gel phase using a higher aliphatic alcohol or a higher fatty acid.

[0083] The skin external preparation composition according to the third embodiment of the present disclosure will be described. The skin external preparation composition of the present disclosure includes at least one of the lamellar gel phase-containing composition according to the first embodiment and the emulsified composition according to the second embodiment. That is, the lamellar gel phase-containing composition according to the first embodiment and the emulsified composition according to the second embodiment can be used as a skin external preparation.

[0084] The lamellar gel phase-containing composition, emulsified composition, and skin external preparation composition of the present disclosure may appropriately contain other components, such as water-soluble alcohols, powders, anionic surfactants, cationic surfactants, amphoteric surfactants, hydrophilic nonionic surfactants, lipophilic nonionic surfactants, water-soluble polymers, thickeners, moisturizers, film formers, oil-soluble ultraviolet absorbers, water-soluble ultraviolet absorbers, sequestering agents, amino acids, organic amines, polymer emulsions, pH adjusters, skin nutrients, vitamins, antioxidants, antioxidant aids, fragrances, etc., as long as they do not inhibit the effects of the present disclosure.

[0085] Examples of the water-soluble alcohol include at least one selected from lower alcohols, polyhydric alcohols, polyhydric alcohol polymers, dihydric alcohol alkyl ethers, dihydric alcohol alkyl ethers, dihydric alcohol ether esters, glycerin monoalkyl ethers, sugar alcohols, monosaccharides, oligosaccharides, polysaccharides, and their derivatives.

[0086] Examples of the lower alcohol include ethanol, propanol, isopropanol, isobutyl alcohol, t-butyl alcohol, and the like.

[0087] Examples of the dihydric alcohol include ethylene glycol, propylene glycol, trimethylene glycol, 1,2-butylene glycol, 1,3-butylene glycol, tetramethylene glycol, 2,3-butylene glycol, pentamethylene glycol, 2-butene-1,4-diol, hexylene glycol, octylene glycol, and the like.

[0088] As the trivalent alcohol, for example, glycerin, trimethylolpropane, etc. can be used. Examples of polyhydric alcohols include dihydric alcohols (e.g., ethylene glycol, propylene glycol, trimethylene glycol, 1,2-butylene glycol, 1,3-butylene glycol, tetramethylene glycol, 2,3-butylene glycol, pentamethylene glycol, 2-butene-1,4-diol, hexylene glycol, octylene glycol, etc.); trihydric alcohols (e.g., glycerin, trimethylolpropane, etc.); tetrahydric alcohols (e.g., pentaerythritol such as 1,2,6-hexanetriol, etc.); pentahydric alcohols (e.g., xylitol, etc.); hexahydric alcohols (e.g., sorbitol, mannitol, etc.); polyhydric alcohol polymers (e.g., diethylene glycol, dipropylene glycol, triethylene glycol, polypropylene glycol, tetraethylene glycol, diglycerin, polyethylene glycol, triglycerin, tetraglycerin, polyglycerin, etc.); dihydric alcohol alkyl ethers (e.g., ethylene glycol monomethyl ether, ethylene glycol monoethyl ether, ethylene glycol monobutyl ether, ethylene glycol monophenyl ether, ethylene glycol monohexyl ether, ethylene glycol mono-2-methylhexyl ether, ethylene glycol isoamyl ether, ethylene glycol benzyl ether, ethylene glycol isopropyl ether, ethylene glycol dimethyl ether, ethylene glycol diethyl ether, ethylene glycol dibutyl ether, etc.);Dihydric alcohol alkyl ethers (e.g., diethylene glycol monomethyl ether, diethylene glycol monoethyl ether, diethylene glycol monobutyl ether, diethylene glycol dimethyl ether, diethylene glycol diethyl ether, diethylene glycol butyl ether, diethylene glycol methyl ethyl ether, triethylene glycol monomethyl ether, triethylene glycol monoethyl ether, propylene glycol monomethyl ether, propylene glycol monoethyl ether, propylene glycol monobutyl ether, propylene glycol isopropyl ether, dipropylene glycol methyl ether, dipropylene glycol ethyl ether, dipropylene glycol butyl ether, etc.); Dihydric alcohol ether esters (e.g., ethylene glycol monomethyl ether acetate, ethylene glycol monoethyl ether acetate, ethylene glycol monobutyl ether acetate, ethylene glycol monophenyl ether acetate, ethylene glycol diadipate, ethylene glycol disuccinate, diethylene glycol monoethyl ether acetate, diethylene glycol monobutyl ether acetate, propylene glycol monomethyl ether acetate, propylene glycol monoethyl ether acetate, propylene glycol monopropyl ether acetate, propylene glycol monophenyl ether acetate, etc.); Glycerol monoalkyl ethers (e.g., chimyl alcohol, ceralkyl alcohol, batyl alcohol, etc.); Sugar alcohols (e.g., sorbitol, maltitol, maltotriose, mannitol, sucrose, erythritol, glucose, fructose, starch hydrolyzate, maltose, xylitol, starch hydrolyzate reduced alcohol, etc.); Glycolide; Tetrahydrofurfuryl alcohol; POE - tetrahydrofurfuryl alcohol; POP - butyl ether; POP·POE - butyl ether; Tripolyoxypropylene glycerin ether; POP - glycerin ether; POP - glycerin ether phosphate; POP·POE - pentaerythritol ether, polyglycerin, etc. can be mentioned.;

[0089] Examples of monosaccharides include at least one selected from trioses (e.g., D-glyceraldehyde, dihydroxyacetone, etc.), tetroses (e.g., D-erythrose, D-erythrulose, D-threose, erythritol, etc.), pentoses (e.g., L-arabinose, D-xylose, L-lyxose, D-arabinose, D-ribose, D-ribulose, D-xylulose, L-xylulose, etc.), hexoses (e.g., D-glucose, D-talose, D-psicose, D-galactose, D-fructose, L-galactose, L-mannose, D-tagatose, etc.), heptoses (e.g., aldoheptose, heptulose, etc.), octoses (e.g., octulose, etc.), deoxy sugars (e.g., 2-deoxy-D-ribose, 6-deoxy-L-galactose, 6-deoxy-L-mannose, etc.), amino sugars (e.g., D-glucosamine, D-galactosamine, sialic acid, amino uronic acid, muramic acid, etc.), uronic acids (e.g., D-glucuronic acid, D-mannuronic acid, L-glucuronic acid, D-galacturonic acid, L-iduronic acid, etc.).

[0090] Examples of oligosaccharides include at least one selected from sucrose, gentiose, umbelliferose, lactose, planteose, isolichenans, α,α-trehalose, raffinose, lichenans, umbellisin, stachyose, verbascosans, etc.

[0091] Examples of polysaccharides include at least one selected from cellulose, quince seed, chondroitin sulfate, starch, galactan, dermatan sulfate, glycogen, gum arabic, heparan sulfate, hyaluronic acid, tragacanth gum, keratan sulfate, chondroitin, xanthan gum, mucoitin sulfate, guar gum, dextran, kerato sulfate, locust bean gum, succinoglucan, carroninic acid, etc.

[0092] Examples of other polyols include at least one selected from polyoxyethylene methyl glucoside (Glucam E-10), polyoxypropylene methyl glucoside (Glucam P-10), and the like.

[0093] The powder is not particularly limited as long as it can be generally used for cosmetic applications and the like. Examples of the powder include inorganic powders (e.g., talc, kaolin, mica, sericite, muscovite, phlogopite, synthetic mica, biotite, lithia mica, calcined mica, calcined talc, vermiculite, magnesium carbonate, calcium carbonate, aluminum silicate, barium silicate, calcium silicate, magnesium silicate, strontium silicate, metal tungstate salts, magnesium, silica, zeolite, glass, barium sulfate, calcined calcium sulfate (calcined gypsum), calcium phosphate, fluorapatite, hydroxyapatite, ceramic powder, metal soaps (e.g., zinc myristate, calcium palmitate, aluminum stearate), boron nitride, etc.); organic powders (e.g., polyamide resin powder (nylon powder), polyethylene powder, polymethyl methacrylate powder, polystyrene powder, copolymer resin powder of styrene and acrylic acid, benzoguanamine resin powder, polytetrafluoroethylene powder, cellulose powder, silicone resin powder, silk powder, wool powder, urethane powder, etc.); inorganic white pigments (e.g., titanium dioxide, zinc oxide, etc.); inorganic red pigments (e.g., iron oxide (red iron oxide), iron titanate, etc.); inorganic brown pigments (γ-iron oxide, etc.), inorganic yellow pigments (yellow iron oxide, loess, etc.), inorganic black pigments (black iron oxide, carbon black, lower titanium oxide, etc.), inorganic purple pigments (e.g., manganese violet, cobalt violet, etc.); inorganic green pigments (e.g., chromium oxide, chromium hydroxide, cobalt titanate, etc.); inorganic blue pigments (e.g., ultramarine, navy blue, etc.); pearl pigments (e.g., titanium oxide-coated mica, titanium oxide-coated bismuth oxychloride, titanium oxide-coated talc, colored titanium oxide-coated mica, bismuth oxychloride, fish scale foil, etc.); metal powder pigments (e.g., aluminum powder, copper powder, etc.);Organic pigments such as zirconium, barium or aluminum lakes (for example, organic pigments such as Pigment Red 201, Pigment Red 202, Pigment Red 204, Pigment Red 205, Pigment Red 220, Pigment Red 226, Pigment Red 228, Pigment Red 405, Pigment Orange 203, Pigment Orange 204, Pigment Yellow 205, Pigment Yellow 401, and Pigment Blue 404, Pigment Red 3, Pigment Red 104, Pigment Red 106, Pigment Red 227, Pigment Red 230, Pigment Red 401, Pigment Red 505, Pigment Orange 205, Pigment Yellow 4, Pigment Yellow 5, Pigment Yellow 202, Pigment Yellow 203, Pigment Green 3 and Pigment Blue 1, etc.); natural pigments (for example, chlorophyll, β-carotene, etc.); wax powders (for example, carnauba wax powder, etc.); starch powders (for example, corn starch powder, rice starch powder, etc.) and the like can be used.;

[0094] Examples of anionic surfactants include, for example, fatty acid soaps (e.g., sodium laurate, sodium palmitate, etc.); higher alkyl sulfate salts (e.g., sodium lauryl sulfate, potassium lauryl sulfate, etc.); alkyl ether sulfate salts (e.g., triethanolamine POE-lauryl sulfate, sodium POE-lauryl sulfate, etc.); N-acyl sarcosinic acids (e.g., sodium lauroyl sarcosinate, etc.); higher fatty acid amide sulfonates (e.g., sodium N-stearoyl-N-methyl taurate, sodium N-myristoyl-N-methyl taurate, sodium coconut oil fatty acid methyl taurate, sodium lauryl methyl tauride, etc.); phosphate ester salts (sodium POE-oleyl ether phosphate, POE-stearyl ether phosphate, etc.); sulfosuccinates (e.g., sodium di-2-ethylhexyl sulfosuccinate, sodium monolauroyl monoethanolamine polyoxyethylene sulfosuccinate, sodium lauryl polypropylene glycol sulfosuccinate, etc.); alkylbenzene sulfonates (e.g., sodium linear dodecylbenzene sulfonate, triethanolamine linear dodecylbenzene sulfonate, linear dodecylbenzene sulfonic acid, etc.); higher fatty acid ester sulfate salts (e.g., sodium hardened coconut oil fatty acid glycerol sulfate, etc.); N-acyl glutamates (e.g., monosodium N-lauroyl glutamate, disodium N-stearoyl glutamate, monosodium N-myristoyl-L-glutamate, etc.); sulfated oils (e.g., castor oil, etc.); POE-alkyl ether carboxylic acids; POE-alkyl allyl ether carboxylates; α-olefin sulfonates; higher fatty acid ester sulfonates; secondary alcohol sulfate salts; higher fatty acid alkyloleamide sulfate salts; sodium lauroyl monoethanolamine succinate; N-palmitoyl aspartic acid ditriethanolamine; sodium caseinate, etc. can be used.

[0095] Examples of cationic surfactants include alkyltrimethylammonium salts (e.g., stearyltrimethylammonium chloride, lauryltrimethylammonium chloride, etc.); alkylpyridinium salts (e.g., cetylpyridinium chloride, etc.); dialkyldimethylammonium salts (e.g., distearyldimethylammonium chloride); poly(N,N'-dimethyl-3,5-methylenepiperidinium) chloride; alkyl quaternary ammonium salts; alkyldimethylbenzylammonium salts; alkylisoquinolinium salts; dialkylmorphonium salts; POE-alkylamines; alkylamine salts; polyamine fatty acid derivatives; amyl alcohol fatty acid derivatives; benzalkonium chloride; benzethonium chloride, etc.

[0096] Examples of amphoteric surfactants include imidazoline-based amphoteric surfactants (e.g., 2-undecyl-N,N,N-(hydroxyethylcarboxymethyl)-2-imidazoline sodium, 2-cocoyl-2-imidazolinium hydroxide-1-carboxyethyloxy 2 sodium salt, etc.); betaine-based surfactants (e.g., 2-heptadecyl-N-carboxymethyl-N-hydroxyethylimidazolinium betaine, lauryldimethylaminoacetic acid betaine, alkyl betaine, amide betaine, sulfobetaine, etc.).

[0097] Hydrophilic nonionic PropertyExamples of surfactants include POE-sorbitan fatty acid esters (e.g., POE-sorbitan monooleate, POE-sorbitan monostearate, POE-sorbitan monooleate, POE-sorbitan tetraoleate, etc.); POE-sorbit fatty acid esters (e.g., POE-sorbit monolaurate, POE-sorbit monooleate, POE-sorbit pentaoleate, POE-sorbit monostearate, etc.); POE-glycerin fatty acid esters (e.g., POE-glycerin monostearate, POE-glycerin monoisostearate, POE-glycerin triisostearate, etc., such as POE-monooleate); POE-fatty acid esters (e.g., POE-distearate, POE-monodioleate, ethylene glycol distearate, etc.); POE-alkyl ethers (e.g., POE-lauryl ether, POE-oleyl ether, POE-stearyl ether, POE-behenyl ether, POE-2-octyldodecyl ether, POE-cholestanol ether, etc.); Pluronic type (e.g., Pluronic (registered trademark), etc.); POE·POP-alkyl ethers (e.g., POE·POP-cetyl ether, POE·POP-2-decyltetradecyl ether, POE·POP-monobutyl ether, POE·POP-hydrogenated lanolin, POE·POP-glycerin ether, etc.); tetra POE·tetra POP-ethylenediamine condensates (e.g., Tetronic, etc.); POE-castor oil hydrogenated castor oil derivatives (e.g., POE-castor oil, POE-hydrogenated castor oil, POE-hydrogenated castor oil monoisostearate, POE-hydrogenated castor oil triisostearate, POE-hydrogenated castor oil monopyroglutamic acid monoisostearic acid diester, POE-hydrogenated castor oil maleic acid, etc.); POE-beeswax·lanolin derivatives (e.g., POE-sorbit beeswax, etc.); alkanolamides (e.g., coconut oil fatty acid diethanolamide, lauric acid monoethanolamide, fatty acid isopropanolamide, etc.); POE-propylene glycol fatty acid esters; POE-alkylamines; POE-fatty acid amides; sucrose fatty acid esters; alkyl ethoxydimethylamine oxide; trioleyl phosphate, etc.

[0098] Lipophilic nonionic Property Examples of the surfactant include sorbitan fatty acid esters (e.g., sorbitan monooleate, sorbitan monoisostearate, sorbitan monolaurate, sorbitan monopalmitate, sorbitan monostearate, sorbitan sesquioleate, sorbitan trioleate, diglycerol sorbitan penta-2-ethylhexanoate, diglycerol sorbitan tetra-2-ethylhexanoate, etc.); glycerin polyglycerin fatty acids (e.g., glycerin monoricinoleate, glycerin monoelaidate, glycerin sesquiolenate, glycerin monostearate, α,α'-glycerin pyroglutamate oleate, glycerin malate monostearate, etc.); propylene glycol fatty acid esters (e.g., propylene glycol monostearate, etc.); hydrogenated castor oil derivatives; glycerin alkyl ethers, etc.

[0099] Examples of the natural water-soluble polymer include plant-based polymers (e.g., gum arabic, tragacanth gum, galactan, guar gum, carob gum, karaya gum, carrageenan, pectin, agar, quince seed (membrillo), algal colloid (cassowary extract), starch (rice, corn, potato, wheat), glycyrrhizic acid); microorganism-based polymers (e.g., xanthan gum, dextran, succinoglucan, pullulan, etc.); animal-based polymers (e.g., collagen, casein, albumin, gelatin, etc.).

[0100] Examples of semi-synthetic water-soluble polymers include starch-based polymers (e.g., carboxymethyl starch, methylhydroxypropyl starch, etc.); cellulose-based polymers (methyl cellulose, ethyl cellulose, methylhydroxypropyl cellulose, hydroxyethyl cellulose, sodium cellulose sulfate, hydroxypropyl cellulose, carboxymethyl cellulose, sodium carboxymethyl cellulose, crystalline cellulose, cellulose powder, etc.); alginic acid-based polymers (e.g., sodium alginate, propylene glycol alginate, etc.).

[0101] Examples of synthetic water-soluble polymers include vinyl-based polymers (e.g., polyvinyl alcohol, polyvinyl methyl ether, polyvinyl pyrrolidone, carboxyvinyl polymer, etc.); polyoxyethylene-based polymers (e.g., polyoxyethylene-polyoxypropylene copolymers of polyethylene glycol 20,000, 40,000, 60,000, etc.); acrylic-based polymers (e.g., sodium polyacrylate, polyethyl acrylate, polyacrylamide, etc.); polyethyleneimine; cationic polymers, etc.

[0102] Examples of thickeners include gum arabic, carrageenan, karaya gum, tragacanth gum, carob gum, quince seed (marmelo), casein, dextrin, gelatin, sodium pectate, sodium alginate, methyl cellulose, ethyl cellulose, carboxymethyl cellulose (CMC), hydroxyethyl cellulose, hydroxypropyl cellulose, polyvinyl alcohol (PVA), polyvinyl methyl ether (PVM), PVP (polyvinyl pyrrolidone), sodium polyacrylate, carboxyvinyl polymer, locust bean gum, guar gum, tamarind gum, cellulose dialkyldimethylammonium sulfate, xanthan gum, magnesium aluminum silicate, bentonite, hectorite, magnesium aluminum silicate (veegum), laponite, silicic anhydride, taurate-based synthetic polymers, acrylate-based synthetic polymers, etc.

[0103] Examples of the humectant include polyethylene glycol, propylene glycol, glycerin, 1,3-butylene glycol, xylitol, sorbitol, maltitol, chondroitin sulfate, hyaluronic acid, mucoitin sulfate, caronic acid, atelocollagen, cholesteryl-12-hydroxystearate, sodium lactate, bile salt, dl-pyrrolidone carboxylate, alkylene oxide derivative, short-chain soluble collagen, diglycerin (EO) PO adduct, Rosa multiflora extract, Galium aparine extract, Melilotus officinalis extract, and the like.

[0104] Examples of the film-forming agent include anionic film-forming agents (for example, (meth)acrylic acid / (meth)acrylic acid ester copolymer, methyl vinyl ether / maleic anhydride copolymer, etc.), cationic film-forming agents (for example, cationized cellulose, dimethyldiallylammonium chloride polymer, dimethyldiallylammonium chloride / acrylamide copolymer, etc.), and nonionic film-forming agents (for example, polyvinyl alcohol, polyvinyl pyrrolidone, polyvinyl acetate, polyacrylate copolymer, (meth)acrylamide, high molecular silicone, silicone resin, trimethylsiloxysilicic acid, etc.).

[0105] Examples of oil-soluble ultraviolet absorbers include benzoic acid-based ultraviolet absorbers (e.g., para-aminobenzoic acid (hereinafter abbreviated as PABA), PABA monoglycerin ester, N,N-dipropoxy PABA ethyl ester, N,N-diethoxy PABA ethyl ester, N,N-dimethyl PABA ethyl ester, N,N-dimethyl PABA butyl ester, N,N-dimethyl PABA ethyl ester, diethylamino hydroxybenzoyl benzoic acid hexyl, etc.); anthranilic acid-based ultraviolet absorbers (e.g., homomenthyl-N-acetylanthranilate, etc.); salicylic acid-based ultraviolet absorbers (e.g., ethylhexyl salicylate, amyl salicylate, menthyl salicylate, homomenthyl salicylate, octyl salicylate, phenyl salicylate, benzyl salicylate, p-isopropanolphenyl salicylate, homosalate, etc.); cinnamic acid-based ultraviolet absorbers (e.g., octyl methoxycinnamate, ethyl-4-isopropylcinnamate, methyl-2,5-diisopropylcinnamate, ethyl-2,4-diisopropylcinnamate, methyl-2,4-diisopropylcinnamate, propyl-p-methoxycinnamate, isopropyl-p-methoxycinnamate, isoamyl-p-methoxycinnamate, octyl-p-methoxycinnamate (2-ethylhexyl-p-methoxycinnamate, ethylhexyl methoxycinnamate), 2-ethoxyethyl-p-methoxycinnamate, cyclohexyl-p-methoxycinnamate, ethyl-α-cyano-β-phenylcinnamate, 2-ethylhexyl-α-cyano-β-phenylcinnamate, glyceryl mono-2-ethylhexanoyl-diparamethoxycinnamate, etc.); 3-(4'-methylbenzylidene)-d,l-camphor, 3-benzylidene-d,l-camphor; 2-phenyl-5-methylbenzoxazole; 2,2'-hydroxy-5-methylphenylbenzotriazole; 2-(2'-hydroxy-5'-t-octylphenyl) benzotriazole; 2-(2'-hydroxy-5'-methylphenylbenzotriazole; dibenzalazine; dianisoylmethane; 4-methoxy-4'-t-butyldibenzoylmethane; 5-(3,3-dimethyl-2-norbornylidene)-3-pentan-2-one, dimorpholinopyridazinone;2-Ethylhexyl-2-cyano-3,3-diphenylacrylate (octocrylene); 2,4-bis-{[4-(2-ethylhexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-(1,3,5)-triazine, benzophenone-based ultraviolet absorbers (for example, 2,4-dihydroxybenzophenone, 2,2'-dihydroxy-4-methoxybenzophenone, 2,2'-dihydroxy-4,4'-dimethoxybenzophenone, 2,2',4,4'-tetrahydroxybenzophenone, 2-hydroxy-4-methoxybenzophenone, 2-hydroxy-4-methoxy-4'-methylbenzophenone, 2-hydroxy-4-methoxybenzophenone-5-sulfonate, 4-phenylbenzophenone, 2-ethylhexyl-4'-phenyl-benzophenone-2-carboxylate, 2-hydroxy-4-n-octoxybenzophenone, 4-hydroxy-3-carboxybenzophenone, etc.) and the like can be mentioned.;

[0106] Examples of water-soluble ultraviolet absorbers include, for example, benzophenone-based ultraviolet absorbers (for example, 2-hydroxy-4-methoxybenzophenone-5-sulfonate, etc.), benzylidene camphor-based ultraviolet absorbers (benzylidene camphor sulfonic acid, terephthalylidene dicamphor sulfonic acid, etc.), phenylbenzimidazole-based ultraviolet absorbers (phenylbenzimidazole sulfonic acid, etc.) and the like.

[0107] Examples of sequestering agents for metal ions include, for example, 1-hydroxyethane-1,1-diphosphonic acid, tetrasodium salt of 1-hydroxyethane-1,1-diphosphonic acid, disodium edetate, trisodium edetate, tetrasodium edetate, sodium citrate, sodium polyphosphate, sodium metaphosphate, gluconic acid, phosphoric acid, citric acid, ascorbic acid, succinic acid, edetic acid, trisodium ethylenediaminehydroxyethyltriacetate, etc.

[0108] Examples of amino acids include neutral amino acids (e.g., threonine, cysteine, etc.); basic amino acids (e.g., hydroxylysine, etc.). Examples of amino acid derivatives include sodium acyl sarcosinate (sodium lauroyl sarcosinate), acyl glutamate salts, sodium acyl β-alanine, glutathione, pyrrolidone carboxylic acid, etc.

[0109] Examples of organic amines include monoethanolamine, diethanolamine, triethanolamine, morpholine, triisopropanolamine, 2-amino-2-methyl-1,3-propanediol, 2-amino-2-methyl-1-propanol, etc.

[0110] Examples of polymer emulsions include acrylic resin emulsion, polyethyl acrylate emulsion, acrylic resin solution, polyalkyl acrylate emulsion, polyvinyl acetate resin emulsion, natural rubber latex, etc.

[0111] Examples of pH adjusters include buffers such as lactic acid - sodium lactate, citric acid - sodium citrate, succinic acid - sodium succinate, etc.

[0112] Examples of vitamins include vitamin A, B1, B2, B6, C, E and their derivatives, pantothenic acid and its derivatives, biotin, etc.

[0113] Examples of antioxidants include tocopherols, dibutylhydroxytoluene, butylhydroxyanisole, gallic acid esters, etc.

[0114] Examples of antioxidant aids include phosphoric acid, citric acid, ascorbic acid, maleic acid, malonic acid, succinic acid, fumaric acid, cephalin, hexametaphosphate, phytic acid, ethylenediaminetetraacetic acid, etc.

[0115] Other compatible ingredients include, for example, preservatives (ethyl paraben, butyl paraben, chlorphenesin, phenoxyethanol, etc.); anti-inflammatory agents (e.g., glycyrrhizic acid derivatives, glycyrrhetinic acid derivatives, salicylic acid derivatives, hinokitiol, zinc oxide, allantoin, etc.); skin-whitening agents (e.g., placenta extract, saxifrage extract, arbutin, etc.); various extracts (e.g., corktree bark, Chinese rhubarb, bitter gourd, peony root, ginseng, birch, sage, loquat, carrot, aloe, Japanese butterbur, iris, grape, Chinese wild yam, loofah, lily, saffron, Chinese foxglove, ginger, primrose, ononis, garlic, capsicum, chimpi, toki, seaweed, etc.), activators (e.g., royal jelly, photosensitizer, cholesterol derivatives, etc.); blood circulation promoters (e.g., nonyl vanillylamide, benzyl nicotinate, β-butoxyethyl nicotinate, capsaicin, zingerone, cantharis tincture, ichthyol, tannic acid, α-borneol, tocopherol nicotinate, inositol hexanicotinate, cyclandelate, cinnarizine, tolazoline, acetylcholine, verapamil, cephalanthin, γ-oryzanol, etc.); anti-seborrheic agents (e.g., sulfur, thiantol, etc.); anti-inflammatory agents (e.g., tranexamic acid, thiotaurine, hypotaurine, etc.), etc.

[0116] Furthermore, the composition of the present disclosure may also appropriately contain caffeine, tannin, verapamil, tranexamic acid and its derivatives, licorice, schizandra fruit, various crude drug extracts such as Chinese foxglove, tocopherol acetate, glycyrrhetinic acid, glycyrrhizic acid and its derivatives or salts thereof, drugs, skin-whitening agents such as vitamin C, magnesium ascorbyl phosphate, ascorbyl glucoside, arbutin, kojic acid, amino acids such as arginine, lysine and their derivatives.

Examples

[0117] Examples of the lamellar gel phase-containing composition and the emulsified composition of the present disclosure will be described below. However, the lamellar gel phase-containing composition and the emulsified composition of the present disclosure are not limited to the following examples. The unit of the content rate of each component shown in each table is mass%.

[0118] [Test Examples 1 to 4] The compositions shown in Tables 1 to 4 were prepared, and small-angle wide-angle X-ray scattering measurement and differential scanning calorimetry (DSC measurement) were performed on each composition. The number of moles in parentheses shown in Tables 1 to 4 indicates the average number of added moles of polyoxyethylene.

[0119] As the first nonionic surfactant which is a two-chain type nonionic surfactant, polyoxyethylene (6 mol) distearate was used. As the second nonionic surfactant having an HLB of 7 to 15, polyoxyethylene (7 mol) cetyl ether (HLB 10), polyoxyethylene (20 mol) hydrogenated castor oil fatty acid glyceryl (HLB 10.5), and polyoxyethylene (10 mol) hydrogenated castor oil fatty acid glyceryl (HLB 7) in a 3:2 mixture, polyoxyethylene (10 mol) glyceryl monostearate (HLB 11), and polyoxyethylene (20 mol) sorbitan monostearate (HLB 14.9) were used.

[0120] The composition of the present disclosure was prepared by melting the nonionic surfactant shown in the following table at 70°C to 80°C to form a single phase, adding ion-exchanged water at 70 to 80°C thereto, stirring, and then cooling.

[0121] Small-angle wide-angle X-ray scattering was measured for the lamellar gel at 25°C. Differential scanning calorimetry was measured for the heat change when the temperature was raised from 30°C to 70°C at 2°C per minute (DSC measurement). The case where the first nonionic surfactant was added was compared with the case where it was not added.

[0122] Figures 1 to 4 show the small-angle wide-angle X-ray scattering charts and DSC charts in Test Examples 1 to 4. In each figure, the upper part (labeled "added") is the chart of the composition to which the first nonionic surfactant was added, and the lower part (labeled "not added") is the chart of the composition to which the first nonionic surfactant was not added.

[0123] In Test Example 1 (Figure 1), the arrows at equal intervals of 1:2 on the small-angle side of the X-ray chart correspond to the long-face intervals of the lamellar gel, indicating that both the sample with the addition of polyoxyethylene (6 mol) distearate and the sample without the addition have a lamellar structure. However, the peak near the scattering vector q = 1.5 nm indicated by the large dotted arrow represents the hexagonal lattice of the α-type structure, and the intensity is strong, indicating that the regularity of the sub-lattice plane has increased. On the other hand, in the case of DSC without addition, the endothermic peak at 40.2 °C shifted to 45.6 °C when polyoxyethylene (6 mol) distearate was added, and at this time, the original peak disappeared, indicating that it is the eutectic point of the mixture. -1 In the vicinity of

[0124] In Test Example 2 (Figure 2), the sample without addition has no melting point and no peak near the scattering vector q = 1.5 nm -1 -1 , indicating that it is a lamellar liquid crystal without a hexagonal structure. However, by adding polyoxyethylene (6 mol) distearate, a hexagonal peak appeared, and a eutectic point occurred at 38.0 °C.

[0125] Also in Test Example 3 (Figure 3) and Test Example 4 (Figure 4), by adding polyoxyethylene (6 mol) distearate, the regularity of the sub-lattice plane increased, the eutectic point appeared, and it was about 5 °C higher than the original melting point.

[0126] From this, it was found that in the composition of the present disclosure, a one-phase self-assembled body is formed by the first nonionic surfactant, the second nonionic surfactant, and water. For example, if it is a two-phase mixture of crystals and lamellar gel, lumps of crystals will precipitate in the composition. The composition of the present disclosure was shown to be a uniform composition. Also, the composition of the present disclosure was found to have high high-temperature stability.

[0127] Figure 5 shows a comparison between the melting enthalpy (with addition) of the composition containing the mixture of the first nonionic surfactant and the second nonionic surfactant in Test Examples 1 to 4, and the melting enthalpy (without addition) of the lamellar gel or lamellar liquid crystal-containing composition of the second nonionic surfactant alone.

[0128] As shown in Figure 5, the addition of polyoxyethylene (6 moles) distearate significantly increased the melting enthalpy of each nonionic Property surfactant aqueous dispersion self-assembly. From the above, it was found that the addition of polyoxyethylene (6 moles) distearate increased the regularity of the self-assembly of the nonionic surfactant and made the lamellar gel stronger.

[0129] [Table 1]

[0130] [Table 2]

[0131] [Table 3]

[0132] [Table 4]

[0133] [Test Example 5] The solubility of the lamellar gel phase of the present disclosure in polar oily components was tested. A composition containing a lamellar gel phase was prepared with the components shown in Table 5. Tripropylene glycol dipivalate (manufactured by Nisshin Oillio Group, Ltd., Saracos TPG), a highly polar oily component, was added in the same mass to this composition, and it was stored in a constant temperature phase at 50°C for one month to confirm the solubility of each lamellar gel in tripropylene glycol dipivalate. The solubility was compared in terms of the volume fraction of the lamellar gel phase. The volume fraction is the number obtained by multiplying the ratio (b / a) of the height (b) from the bottom surface to the upper surface of the lamellar gel phase (cloudy part) to the height (a) from the bottom surface to the liquid surface by 100. Figure 6 shows photographs of the compositions of Test Examples 5-1 to 5-4. The compositions of Test Examples 5-1 and 5-2 are the same as those of Test Examples 3-1 and 3-2.

[0134] In the composition of Test Example 5-2 to which the first nonionic surfactant was not added, the lamellar gel was dissolved in the oily component. Also, in Test Examples 5-3 and 5-4 in which a higher alcohol was added to form a lamellar gel phase, there was a remaining lamellar gel phase that did not dissolve in the polar oil component, but more of it was dissolved than the lamellar gel phase of the present disclosure shown in Test Example 5-1. From this, it was found that the lamellar gel phase of the present disclosure has low solubility in highly polar oily components.

[0135] [Table 5]

[0136] [Test Example 6] The emulsion stability of an emulsion using the lamellar gel phase of the present disclosure was tested. After preparing a lamellar gel phase with the components shown in Table 6, tripropylene glycol dipivalate was emulsified. The emulsified composition was stored at 50°C for one month to confirm the presence or absence of coalescence of the emulsion oil droplets.

[0137] In Test Examples 6-5 to 6-7 where the first nonionic surfactant was not used, coalescence of the emulsified oil droplets was confirmed. On the other hand, in Test Examples 6-1 to 6-4 using the lamellar gel phase of the present disclosure, coalescence of the emulsified oil droplets was not confirmed. From the results of Test Examples 1 to 5, the lamellar gel phase of the present disclosure has a stronger structure and thus hardly dissolves in tripropylene glycol dipalmitate. For this reason, it is considered that the lamellar gel phase was not incorporated into the oil droplets and coalescence of the emulsion particles did not occur. In contrast, in Test Examples 6-5 to 6-7, it is considered that coalescence of the oil droplets occurred because the lamellar gel phase dissolved in the oil droplets.

[0138]

Table 6

[0139] [Test Example 7] The feel of use of an oil-in-water (O / W) type emulsified topical skin preparation using the lamellar gel phase of the present disclosure was tested. Test Examples 7-1 and 7-2 are emulsions using the lamellar gel phase of the present disclosure. Comparative control Test Example 7-3 is a lamellar gel phase-containing emulsion using behenic acid soap, stearic acid soap, polyoxyethylene (5 mol) glyceryl monostearate, glyceryl monostearate, and behenyl glucoside.

[0140] A professional panel applied the composition of Test Example 7-1 to half of the face and the composition of Test Example 7-3 to the remaining half of the face, and evaluated the feel of use of the composition of Test Example 7-1 with respect to the composition of Test Example 7-3 on a 7-point scale from -3 to +3 for each evaluation item shown in FIG. 7. The feel of use of the composition of Test Example 7-2 with respect to Test Example 7-3 was similarly evaluated. FIG. 7 shows the evaluation results of Test Example 7-1. FIG. 8 shows the evaluation results of Test Example 7-2. An evaluation score of 0 was regarded as the same feel of use as Test Example 7-3.

[0141] The emulsion using the lamellar gel phase of the present disclosure was found to have better elongation, a sense of penetration, and be refreshing, and yet have a high softness and firmness of the skin after application, compared to the emulsion using the lamellar gel phase of Test Example 7-3. From the results shown in FIGS. 7 and 8, it was found that the lamellar gel phase of the present disclosure has a better usability than the lamellar gel phase of Test Example 7-3.

[0142]

Table 7

[0143] Formulation examples of the composition of the present disclosure are given below. The application examples of the composition of the present disclosure are not limited by the following formulation examples. The unit of the content of each component shown in the table is mass%.

[0144] [Formulation Example 1 Emulsion (Table 8)] Emulsification was carried out by a conventional method to prepare the emulsion shown in Table 8. The obtained emulsion had quick skin compatibility, was refreshing, and had good stability.

[0145]

Table 8

[0146] [Formulation Example 2 Skin Lotion (Table 9)] Emulsification was carried out by a conventional method to obtain the skin lotion shown in Table 9. The obtained skin lotion had quick skin compatibility, was refreshing, and had good stability.

[0147]

Table 9

[0148] [Formulation Example 3 Emulsion (Table 10)] Emulsification was carried out by a conventional method to obtain the emulsion shown in Table 10. The obtained emulsion had quick skin compatibility, was refreshing, and had good stability.

[0149]

Table 10

[0150] [Formulation Example 4 Sunscreen Cream (Table 11)] Emulsification was carried out by a conventional method to obtain the sunscreen cream shown in Table 11. The obtained sunscreen cream had quick skin adaptability, was refreshing, and had good stability.

[0151]

Table 11

[0152] [Formulation Example 5 Water-in-Oil (W / O) Cream (Table 12)] Emulsification was carried out by a conventional method to obtain the water-in-oil (W / O) cream shown in Table 12. The obtained water-in-oil cream had quick skin adaptability, was refreshing, and had good stability.

[0153]

Table 12

[0154] The lamellar gel phase-containing composition, emulsified composition, and skin external preparation composition of the present invention, and the production methods thereof, are described based on the above embodiments and examples. However, they are not limited to the above embodiments and examples, and within the scope of the present invention and based on the basic technical idea of the present invention, various modifications, changes, and improvements can be made to each disclosed element (including the elements described in the claims, the specification, and the drawings). Also, within the scope of the claims of the present invention, various combinations, substitutions, or selections of each disclosed element are possible.

[0155] Further problems, objects, and forms (including modified forms) of the present invention will also be clarified from all the disclosed matters of the present invention including the claims.

[0156] Regarding the numerical ranges described in this document, even in the case where there is no separate description, any numerical value or range included within the range should be construed as specifically described in this document.

[0157] Some or all of the above embodiments can also be described as follows, but are not limited to the following description. Each supplementary note can also be combined with each claim described in the claims. [Supplementary Note 1] A melting step of melting a first nonionic surfactant, A water addition step of adding water to the melted first nonionic surfactant and stirring, A method for producing a lamellar gel phase-containing composition, comprising: [Supplementary Note 2] The production method according to the supplementary note, wherein in the melting step, the first nonionic surfactant and the second nonionic surfactant are melted. [Supplementary Note 3] The production method according to the supplementary note, wherein in the water addition step, before the addition, the temperature is heated to within a range of ±15°C with respect to the heating temperature of the first nonionic surfactant. [Supplementary Note 4] A solution preparation step of dissolving a first nonionic surfactant in a polyhydric alcohol to prepare a solution, A step of adding an oily component to the solution and emulsifying, A step of adding water after emulsification, A method for producing an emulsified composition, comprising: [Supplementary Note 5] The production method according to the supplementary note, wherein in the solution preparation step, the first nonionic surfactant and the second nonionic surfactant are melted. [Supplementary Note 6] The production method according to the supplementary note, wherein the polyhydric alcohol is a dihydric alcohol. [Supplementary Note 7] The production method according to the supplementary note, wherein the first nonionic surfactant is represented by the formula shown in Chemical Formula 1 above. [Supplementary Note 8] The production method according to the supplementary note, wherein the second nonionic surfactant is at least one selected from the group of compounds represented by the formulas shown in Chemical Formulas 2 to 5 above. [Supplementary Note 9] A method of use, which comprises applying to the skin at least one selected from the group consisting of the lamellar gel phase-containing composition, the emulsion composition, and the composition for external use on skin of the present disclosure.

Industrial Applicability

[0158] The lamellar gel phase-containing composition, the emulsion composition, and the composition for external use on skin of the present disclosure can be applied to, for example, cosmetics applied to the skin, cosmetics applied to the hair, cleaning agents, and the like. For example, the composition for external use on skin of the present disclosure can be applied to antiperspirants, deodorants, sunscreen cosmetics, skin care agents, makeup cosmetics, makeup removers, hair shampoos, hair styling agents, and the like.

Claims

1. A composition having a lamellar gel phase, 0.1% to 40% by mass of a first nonionic surfactant represented by the formula shown in Chemical Formula 1 below, A second nonionic surfactant having an HLB of 7 to 15, water, and the second nonionic surfactant is at least one selected from the group of compounds represented by the formulas shown in Chemical Formulas 3 to 5 below, the second nonionic surfactant is 0.05% to 60% by mass based on the mass of the composition, and is 0.5 to 4 parts by mass with respect to 1 part by mass of the first nonionic surfactant, the first nonionic surfactant, the second nonionic surfactant, and water constitute at least a part of the lamellar gel phase, the lamellar gel phase has a eutectic point and a melting enthalpy higher than those of the lamellar gel phase formed by any one of the second nonionic surfactants represented by the formulas of Chemical Formulas 3 to 5, A composition in which the content of higher aliphatic alcohol or higher fatty acid is 1% by mass or less based on the mass of the composition. 【Chemical Formula 1】 (In the formula shown in Chemical Formula 1, R １ is a linear acyl group or linear alkyl group having 16 to 24 carbon atoms, R ２ is an alkylene group having 2 to 4 carbon atoms, R ３ is a linear acyl group or linear alkyl group having 16 to 24 carbon atoms, and k represents an integer of 4 to 15.) 【Chemical Formula 3】 (In the formula shown in Chemical Formula 3, R6, R10, and R14 are each an alkylene group having 2 to 4 carbon atoms, R7, R11, and R15 are each an alkylene group having 8 to 12 carbon atoms, R8, R12, and R16 are each an alkyl group having 4 to 8 carbon atoms, R9, R13, and R17 are each a polymer of 12-hydroxystearic acid or a polymer of alkylene polyol, m, n, and o are each a natural number, and the sum of m, n, and o is 10 to 60.) [Chemical Formula 4] (In the formula shown in Chemical Formula 4, R18 is a linear acyl group or a linear alkyl group having 16 to 24 carbon atoms, R19 and R20 are each an alkylene group having 2 to 4 carbon atoms, p and q are each a natural number, and the sum of p and q is 5 to 20.) [Chemical Formula 5] (In the formula shown in Chemical Formula 5, R21, R22, R23, and R25 are each an alkylene group having 2 to 4 carbon atoms, r, s, t, and u are each a natural number, the sum of r, s, t, and u is 5 to 30, and R24 is a linear acyl group or a linear alkyl group having 16 to 24 carbon atoms.)

2. The composition according to claim 1, wherein the first nonionic surfactant is polyethylene glycol distearate in which k in the formula of Chemical Formula 1 is 4 to 8.

3. The composition according to any one of claims 1 to 2, an oily component, water, and an emulsified composition in which the oily component or water is emulsified in the lamellar gel phase.

4. A composition for external use on the skin, containing the composition according to any one of claims 1 to 3.

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