Essence with anti-wrinkle, repairing and skin-brightening effects as well as preparation method and application thereof

Abstract

The invention belongs to the technical field of cosmetics, and particularly relates to essence with anti-wrinkle, repairing and skin-brightening effects as well as a preparation method and application of the essence. The essence is prepared from the following components in parts by weight: 10 to 70 parts of herba centellae extract, 0.0015 to 0.04 part of crocus sativus extract, 0.5 to 2.5 parts of spirulina maxima extract, 0.015 to 0.2 part of radix gentianae extract, 0.1 to 1.5 parts of panthenol, 0.25 to 1.5 parts of leuconostoc / radish root fermentation product filtrate, 0.1 to 1.5 parts of carnosine and 0.21 to 5.3 parts of anti-wrinkle components. According to the essence, various effective components such as the centella asiatica extract, the spirulina maxima extract and the radix gentianae extract are matched for use, a unique composite formula is formed, all the components promote one another, the anti-wrinkle, repairing and skin brightening effects of the essence can be remarkably enhanced, and therefore all-around skin care is provided for consumers, and the essence has a good market prospect. The overall quality of the skin can be effectively improved.

Description

Technical Field

[0001] The present invention belongs to the technical field of cosmetics, and in particular relates to an essence with anti-wrinkle and skin-repairing and lightening effects, and a preparation method and application thereof. Background Art

[0002] With changes in modern lifestyles and increasing environmental pollution, skin problems, particularly aging, wrinkles, and uneven skin tone, have become a major concern. While skin aging is a natural process, it can also be accelerated by environmental factors, UV radiation, stress, and unhealthy lifestyle habits. With age, the amount of collagen and elastin in the skin decreases, reducing elasticity and leading to fine lines and wrinkles. The skin also loses its radiance and brightness, leading to dullness and roughness. Consequently, demand for skincare products with anti-aging, anti-wrinkle, and skin-repairing and brightening properties is increasing.

[0003] There are many anti-aging and anti-wrinkle essences on the market, but most products can only improve surface fine lines and wrinkles locally and are unable to fundamentally repair deep skin damage. In addition, some products may cause skin irritation and allergic reactions due to single ingredients or improper formulas.

[0004] Therefore, there is an urgent need to develop a skin care product with anti-wrinkle and skin-repairing and lightening effects to effectively improve skin elasticity, slow down the aging process, and repair skin radiance, thereby achieving long-lasting anti-aging, anti-wrinkle and skin-lightening effects. Summary of the Invention

[0005] The purpose of the present invention is to overcome the deficiencies of the above-mentioned prior art and provide an essence with anti-wrinkle and skin-repairing and lightening effects, as well as a preparation method and application thereof.

[0006] To achieve the above objectives, the technical solutions adopted by the present invention include:

[0007] In a first aspect, the present invention provides an essence with anti-wrinkle and skin-repairing and brightening effects, the essence comprising the following components in parts by weight: 10-70 parts of Centella asiatica extract, 0.0015-0.04 parts of Crocus sativus extract, 0.5-2.5 parts of Spirulina maxima extract, 0.015-0.2 parts of Gentiana lutea root extract, 0.1-1.5 parts of panthenol, 0.25-1.5 parts of Leuconostoc / radish root fermentation product filtrate, 0.1-1.5 parts of carnosine, and 0.21-5.3 parts of an anti-wrinkle ingredient; the anti-wrinkle ingredient comprises at least one of acetyl hexapeptide-8, soluble collagen, and collagen.

[0008] The essence of the present invention can effectively increase skin elasticity, reduce the formation of facial wrinkles, help repair damaged skin barriers, improve uneven skin tone, and thus achieve good skin repair and brightening effects through the combined action of multiple natural plant extracts and active ingredients. Among them, Centella asiatica extract is rich in saponins, flavonoids and polysaccharides, which have the effects of promoting skin repair, anti-inflammatory, and antioxidant, thereby accelerating the repair of the skin barrier and helping to improve the skin's elasticity and firmness; Saffron extract is rich in natural antioxidants such as flavonoids and polyphenols, which can improve uneven skin tone, and help slow down the aging process through antioxidant effects, and enhance the skin's radiance; Spirulina maxima extract is rich in vitamins, minerals, amino acids and plant proteins, which can improve the metabolism of skin cells, promote blood circulation, and help enhance the vitality and radiance of the skin; Gentiana root extract can help reduce skin redness and irritation, while promoting skin self-repair; The filtrate of the fermentation product of Bacillus thuringiensis / radish root has natural antibacterial, moisturizing and antioxidant functions, which can help enhance the skin's barrier function, improve the balance of skin microecology, and promote the metabolism of skin cells; Carnosine has good antioxidant and anti-glycation effects, which can effectively neutralize free radicals, slow down the skin's aging process, and maintain the skin's elasticity and firmness.

[0009] Extensive testing and research revealed that by combining these active ingredients to create a serum, the interactions between the components allow the serum to deliver superior anti-wrinkle, repair, brighten, and moisturize skin, providing consumers with comprehensive skin care solutions. Furthermore, the excellent repairing properties of Centella asiatica extract, as the primary ingredient, synergize with the three active ingredients: Spirulina maxima extract, gentiana root extract, and carnosine, further enhancing the anti-wrinkle and brightening effects.

[0010] Furthermore, the inventors explored the dosages of the various components and discovered that when the Spirulina maxima extract, gentiana root extract, and carnosine are used within the small amounts specified in the present invention, they synergistically enhance the serum's anti-aging, skin-repairing, and skin-brightening effects. However, if the ratio of the three components exceeds the preferred range, the serum's skincare effectiveness is reduced. Therefore, through scientifically formulated ratios and precise dosage control, the present invention ensures the serum's superior effects, providing consumers with a more effective and safer skincare product.

[0011] Preferably, the essence comprises the following components in parts by weight: 15-65 parts of Centella asiatica extract, 0.0045-0.015 parts of saffron extract, 1-2 parts of Spirulina maxima extract, 0.025-0.1 parts of gentian root extract, 0.2-1 parts of panthenol, 0.4-1 parts of leuconostoc / radish root fermentation product filtrate, 0.12-1 parts of carnosine and 0.45-3.15 parts of anti-wrinkle ingredients.

[0012] Preferably, the essence comprises the following components in parts by weight: 55 parts of Centella asiatica extract, 0.0075 parts of saffron extract, 1.5 parts of Spirulina maxima extract, 0.075 parts of gentian root extract, 0.5 parts of panthenol, 0.75 parts of leuconostoc / radish root fermentation product filtrate, 0.5 parts of carnosine and 1.12 parts of anti-wrinkle ingredients.

[0013] Through experimental research, it was found that when the components are compounded using the above-mentioned optimal dosage ratio, their respective functions can be maximized, thereby effectively improving skin elasticity and repairing skin brightness, thereby achieving long-lasting anti-aging, anti-wrinkle and skin-lightening effects.

[0014] Preferably, the anti-wrinkle ingredient is acetyl hexapeptide-8, soluble collagen and collagen, and the mass ratio of acetyl hexapeptide-8, soluble collagen and collagen is (0.01-0.3):(0.1-2.5):(0.1-2.5).

[0015] Acetyl hexapeptide-8 can inhibit muscle contraction, reduce wrinkle formation, and improve skin firmness; soluble collagen can help enhance skin elasticity and density, promote skin self-repair and regeneration, and improve the skin's overall structure; collagen components help strengthen the skin's moisturizing function, increase hydration, and further alleviate fine lines and wrinkles caused by dryness. Experimental research has found that the present invention uses acetyl hexapeptide-8, soluble collagen, and collagen in a preferred ratio as auxiliary anti-wrinkle ingredients, which can further enhance the anti-wrinkle effect of the essence, delay the skin aging process, and restore the skin to a smooth and firm state.

[0016] Preferably, the mass ratio of acetyl hexapeptide-8, soluble collagen and collagen is (0.05-0.15): (0.2-1.5): (0.2-1.5).

[0017] More preferably, the mass ratio of acetyl hexapeptide-8, soluble collagen and collagen is 0.12:0.5:0.5.

[0018] Preferably, the essence further comprises the following components in parts by weight: 1.4-15.5 parts of moisturizing agent, 0.06-0.7 parts of thickening agent, 0.01-0.05 parts of chelating agent and 0.1-1 parts of antioxidant.

[0019] Preferably, the essence further comprises the following components in parts by weight: 2.8-14.7 parts of moisturizing agent, 0.15-0.52 parts of thickening agent, 0.01-0.05 parts of chelating agent and 0.2-0.5 parts of antioxidant.

[0020] More preferably, the essence further comprises the following components in parts by weight: 7.7 parts of moisturizing agent, 0.35 parts of thickening agent, 0.03 parts of chelating agent and 0.4 parts of antioxidant.

[0021] Preferably, the moisturizing agent includes at least one of butylene glycol, polyglycerol-10, glucomannan, hydrolyzed sodium hyaluronate, sodium hyaluronate, 1,3-propylene glycol and 1,2-hexanediol.

[0022] Preferably, the thickener comprises at least one of ammonium acryloyldimethyltaurate / VP copolymer and sclerotium gum.

[0023] Preferably, the chelating agent comprises disodium EDTA; and / or the antioxidant comprises p-hydroxyacetophenone.

[0024] In a second aspect, the present invention provides the use of the essence with anti-wrinkle and skin-repairing and lightening effects in cosmetics.

[0025] In a third aspect, the present invention provides a method for preparing the essence having anti-wrinkle and skin-repairing and lightening effects, comprising the following steps:

[0026] S1. Mix a moisturizer, a thickener, a chelating agent, and water, heat to 82-85° C., and stir evenly to obtain a mixture A;

[0027] S2. Add panthenol and antioxidant to mixture A, homogenize at 2500-3000 rpm / min for 5-10 minutes, and keep warm for 5-10 minutes to obtain mixture B;

[0028] S3. Cooling the mixture B to below 38° C., adding Centella asiatica extract, Crocus sativus extract, Spirulina maxima extract, Gentiana lutea root extract, carnosine, Leuconostoc / radish root fermentation product filtrate, and anti-wrinkle ingredients, and homogenizing at 1200-1800 rpm / min for 5-10 minutes until completely dispersed, thereby obtaining the essence.

[0029] Compared with the prior art, the present invention has the following beneficial effects:

[0030] (1) The essence of the present invention uses a combination of the main active ingredient, Centella asiatica extract, and multiple active ingredients such as Spirulina maxima extract and Gentiana root extract to form a unique composite formula. The components cooperate with each other and promote each other, which can significantly enhance the anti-wrinkle, repair, brightening and moisturizing effects of the essence, thereby providing consumers with comprehensive skin care and helping to effectively improve the overall quality of the skin;

[0031] (2) The present invention also uses acetyl hexapeptide-8, soluble collagen and collagen in a preferred amount ratio as auxiliary anti-wrinkle ingredients. By precisely controlling the ratio of each ingredient, the anti-wrinkle effect of the essence can be further enhanced, the skin aging process can be slowed down, the skin can be restored to a smooth and firm state, and the youthful state of the skin can be effectively prolonged. BRIEF DESCRIPTION OF THE DRAWINGS

[0032] Figure 1 This is a diagram showing the appearance of the essence prepared in Example 1. DETAILED DESCRIPTION

[0033] To better illustrate the purpose, technical solutions and advantages of the present invention, the present invention will be further described below in conjunction with specific embodiments. Those skilled in the art should understand that the specific embodiments described herein are only used to explain the present invention and are not intended to limit the present invention.

[0034] Unless otherwise specified, all raw materials involved in the following examples and comparative examples are commercially available general materials.

[0035] Examples 1-7

[0036] Examples 1-7 provide an essence with anti-wrinkle and skin-repairing and lightening effects. The formula of the essence is shown in Table 1 (total weight parts is 100 parts). The preparation method of the essence with anti-wrinkle and skin-repairing and lightening effects comprises the following steps:

[0037] S1. Mix a moisturizer, a thickener, a chelating agent, and water, heat to 82-85° C., and stir evenly to obtain a mixture A;

[0038] S2. Add panthenol and antioxidant to mixture A, homogenize at 2800 rpm for 7 minutes, and keep warm for 6 minutes to obtain mixture B;

[0039] S3. Cooling the mixture B to below 38° C., adding Centella asiatica extract, Crocus sativus extract, Spirulina maxima extract, Gentiana lutea root extract, carnosine, Leuconostoc / radish root fermentation product filtrate, and anti-wrinkle ingredients, and homogenizing at 1500 rpm / min for 5 minutes until completely dispersed, thereby obtaining the essence.

[0040] Table 1 Formula of the essence described in Examples 1-7 (parts by weight)

[0041]

[0042]

[0043] Comparative Examples 1-7

[0044] Comparative Examples 1-7 provide an anti-wrinkle and skin-repairing and lightening serum. The formula of the serum is shown in Table 2 (total weight parts is 100 parts). The preparation method of the anti-wrinkle and skin-repairing and lightening serum is the same as that of the examples, differing only in the formula.

[0045] Table 2 Formula of the essence described in Comparative Examples 1-7 (parts by weight)

[0046]

[0047]

[0048]

[0049] Comparative Example 8

[0050] This comparative example provides an essence with anti-wrinkle and skin-repairing and brightening effects, which differs from Example 1 only in that an equal amount of aloe vera extract is used to replace the Centella asiatica extract, and the other components and amounts remain unchanged.

[0051] Comparative Example 9

[0052] This comparative example provides an anti-aging repair essence, which differs from Example 1 only in that an equal amount of Chlorella vulgaris extract is used to replace the Spirulina maxima extract, and the other components and amounts remain unchanged.

[0053] Comparative Example 10

[0054] This comparative example provides an anti-aging repair essence, which differs from Example 1 only in that an equal amount of pentapeptide-8 is used to replace carnosine, and the other components and amounts remain unchanged.

[0055] Effect Examples

[0056] 1. Safety testing:

[0057] The anti-wrinkle and skin-repairing and lightening essences prepared in Examples 1-7 and Comparative Examples 1-10 were used as samples to test their safety. The specific testing method is as follows:

[0058] Test population: 170 subjects with facial wrinkles, aged 35-55, were randomly divided into 17 groups of 10. All subjects met the selection criteria for human skin patch testing as specified in the "Safety Technical Specifications for Cosmetics" (2015 edition).

[0059] Test method: The essences prepared in Examples 1-7 and Comparative Examples 1-10 were used for patch tests. Qualified patch test equipment was selected and a closed patch test method was used. Approximately 0.020-0.025 ml of the test substance was placed in the patch tester. Medical tape was applied to the curved side of the subject's forearm. The test substance was evenly applied to the skin with light pressure using the palm of the hand. The test substance patch tester was removed after 24 hours. The skin reaction was observed 0.5, 24, and 48 hours after the removal of the test substance patch tester. The results were recorded according to the skin reaction grading standard in the "Technical Specifications for Safety of Cosmetics" (2015 edition).

[0060] The results of the human skin patch test showed that there was no positive reaction among 170 people. According to the "Technical Specifications for Safety of Cosmetics" (2015 edition), the test substance will not cause adverse skin reactions and the sample is safe and non-irritating.

[0061] 2. Human testing:

[0062] The 170 subjects with facial wrinkles selected above were randomly divided into 17 groups, with 10 participants in each group. The serums described in Examples 1-7 and Comparative Examples 1-10 were then tested for their anti-aging and skin-repairing and brightening effects. After cleansing their faces in the morning and evening, the volunteers were then tested for the serums described in Examples 1-7 and Comparative Examples 1-10 until absorbed. After 28 consecutive days of use, the volunteers were tested on the evening of the 28th day, after cleansing their faces, and then applied to their faces for testing.

[0063] (1) Changes in skin elasticity

[0064] A multi-probe skin tester was used to test the subjects' faces before and after using the serum. Based on the principles of suction and tension, a constant negative pressure was applied vertically to the skin. The pressure was then removed and the change in skin displacement over a specified period of time was measured. A larger value indicates greater skin elasticity. The improvement in skin elasticity was calculated as (test value - initial value) / initial value. The test results were averaged for each group. The specific results are shown in Table 3.

[0065] (2) Changes in transepidermal water loss (TEWL)

[0066] Using the German CK Tewameter™ Hex skin tester, the transepidermal water loss (TEWL) of the subjects was measured before using the serum. This was recorded as the initial value. The TEWL was then measured again after 28 days of use, also recorded as the test value. Finally, the rate of change in TEWL was calculated. A greater rate of change indicates a better repair effect. Rate of change = (initial value - test value) / initial value. The test results were averaged for each group. The specific results are shown in Table 3.

[0067] (3) Changes in facial spots

[0068] Using the VISIA facial imaging analyzer (Canfield, USA, seventh generation), we measured facial spots before and after using the serum to investigate its skin-lightening effect. A higher percentage indicates fewer spots and better skin condition. The spot reduction rate was calculated as (test value - initial value) / initial value. The test results were averaged for each group. The specific results are shown in Table 3.

[0069] Table 3

[0070]

[0071]

[0072] As can be seen from the results in Table 3, the essences prepared in the examples of the present invention can effectively improve skin elasticity, improve skin condition, and achieve good anti-aging, repairing and skin-lightening effects. In particular, the essence described in Example 1 has the best anti-aging and skin-lightening effects. However, in Examples 6-7, since the ratio of acetyl hexapeptide-8, soluble collagen and collagen in the anti-aging ingredients exceeds the preferred range of the present invention, the anti-aging, repairing and other effects of the prepared essences are reduced to a certain extent compared with Example 1, but the overall effect is still improved compared with the comparative example.

[0073] In Comparative Examples 1-5, when any one or more of the three active ingredients, carnosine, spirulina maxima extract, and gentian root extract, were missing, the anti-aging, firming, and skin-repairing and brightening effects of the prepared essences were significantly reduced compared to the examples. In Comparative Examples 6-7, when the dosage ratios of the three components exceeded the specified ranges of the present invention, the various effects of the essences also decreased. These results indicate that when the carnosine, spirulina maxima extract, and gentian root extract selected in the formula of the present invention are combined with other components within a specific dosage ratio to prepare the essence, the three components interact with each other, significantly enhancing the anti-aging, firming, and other effects of the essence at lower dosages, exerting an excellent synergistic effect. None of the three components can be omitted. In Comparative Examples 8-10, when the Centella asiatica extract, spirulina maxima extract, and carnosine in the formulas were replaced with other components with similar efficacy, the anti-aging, skin-repairing, and skin-brightening effects of the prepared essences also decreased to a certain extent, further demonstrating that the carefully formulated components in the formula of the present invention cannot be simply replaced.

[0074] 3. Stability test:

[0075] The stability of the serum prepared in Examples 1-7 was tested, and the specific results are as follows:

[0076] Internal control standards (2 months at 45±2°C and 2 months at -18±2°C) exceed national and light industry standards. Three high-low temperature cycle tests were conducted: 24 hours at 45±2°C and 24 hours at -18±2°C. The results are shown in Table 4.

[0077] Table 4

[0078]

[0079] The results in Table 4 show that the essence prepared in the examples of the present invention has good stability in product application.

[0080] Finally, it should be noted that the above embodiments are intended to illustrate the technical solutions of the present invention rather than to limit the scope of protection of the present invention. Although the present invention has been described in detail with reference to preferred embodiments, those skilled in the art should understand that the technical solutions of the present invention may be modified or replaced by equivalents without departing from the essence and scope of the technical solutions of the present invention.

Claims

1. An essence with anti-wrinkle and skin-repairing and lightening effects, characterized in that: The essence comprises the following components in parts by weight: 10-70 parts of Centella asiatica extract, 0.0015-0.04 parts of Crocus sativus extract, 0.5-2.5 parts of Spirulina maxima extract, 0.015-0.2 parts of Gentiana lutea root extract, 0.1-1.5 parts of panthenol, 0.25-1.5 parts of Leuconostoc / Radish root fermentation product filtrate, 0.1-1.5 parts of carnosine, and 0.21-5.3 parts of anti-wrinkle ingredients; The anti-wrinkle ingredient includes at least one of acetyl hexapeptide-8, soluble collagen and collagen.

2. The essence with anti-wrinkle and skin-repairing and lightening effects according to claim 1, characterized in that: The essence comprises the following components in parts by weight: 15-65 parts of Centella asiatica extract, 0.0045-0.015 parts of saffron extract, 1-2 parts of Spirulina maxima extract, 0.025-0.1 parts of gentian root extract, 0.2-1 parts of panthenol, 0.4-1 parts of leuconostoc / radish root fermentation product filtrate, 0.12-1 parts of carnosine and 0.45-3.15 parts of anti-wrinkle ingredients.

3. The essence with anti-wrinkle and skin-repairing and lightening effects according to claim 2, characterized in that: The essence comprises the following components in parts by weight: 55 parts of Centella asiatica extract, 0.0075 parts of saffron extract, 1.5 parts of Spirulina maxima extract, 0.075 parts of gentian root extract, 0.5 parts of panthenol, 0.75 parts of leuconostoc / radish root fermentation product filtrate, 0.5 parts of carnosine and 1.12 parts of anti-wrinkle ingredients.

4. The essence with anti-wrinkle and skin-repairing and lightening effects according to claim 1, characterized in that: The anti-wrinkle ingredients include acetyl hexapeptide-8, soluble collagen and collagen, and the mass ratio of acetyl hexapeptide-8, soluble collagen and collagen is (0.01-0.3): (0.1-2.5): (0.1-2.5).

5. The essence with anti-wrinkle and skin-repairing and lightening effects according to any one of claims 1 to 3, characterized in that: The essence further comprises the following components in parts by weight: 1.4-15.5 parts of a moisturizing agent, 0.06-0.7 parts of a thickener, 0.01-0.05 parts of a chelating agent and 0.1-1 parts of an antioxidant.

6. The essence with anti-wrinkle and skin-repairing and lightening effects according to claim 5, characterized in that: The moisturizing agent includes at least one of butylene glycol, polyglycerol-10, glucomannan, hydrolyzed sodium hyaluronate, sodium hyaluronate, 1,3-propylene glycol and 1,2-hexanediol.

7. The essence with anti-wrinkle and skin-repairing and lightening effects according to claim 5, characterized in that: The thickener includes at least one of ammonium acryloyldimethyltaurate / VP copolymer and sclerotium gum.

8. The essence with anti-wrinkle and skin-repairing and lightening effects according to claim 5, characterized in that: The chelating agent includes disodium EDTA; and / or the antioxidant includes p-hydroxyacetophenone.

9. Use of the essence with anti-wrinkle and skin-repairing and lightening effects according to any one of claims 1 to 8 in cosmetics.

10. The method for preparing the essence with anti-wrinkle and skin-repairing and lightening effects according to any one of claims 5 to 8, characterized in that: The following steps are involved: S1. Mix a moisturizer, a thickener, a chelating agent, and water, heat to 82-85° C., and stir evenly to obtain a mixture A; S2. Add panthenol and antioxidant to mixture A, homogenize at 2500-3000 rpm / min for 5-10 minutes, and keep warm for 5-10 minutes to obtain mixture B; S3. Cooling the mixture B to below 38° C., adding Centella asiatica extract, Crocus sativus extract, Spirulina maxima extract, Gentiana lutea root extract, carnosine, Leuconostoc / radish root fermentation product filtrate, and anti-wrinkle ingredients, and homogenizing at 1200-1800 rpm / min for 5-10 minutes until completely dispersed, thereby obtaining the essence.

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