Cosmetic composition having antioxidant properties

Abstract

Cosmetic composition with antioxidant properties The present invention relates to cosmetic compositions that have antioxidant properties and are suitable for a variety of skin types. [Selection diagram] No diagram

Description

Technical Field

[0001] The present invention relates to sunscreen and sunscreen agents for cosmetics having specific effectiveness with respect to a certain skin type. More generally, the present invention relates to cosmetic compositions having antioxidant properties and suitable for various skin types.

Background Art

[0002] Many sunscreen agents are already known which usually contain UV filters for the ultraviolet A (UVA) and ultraviolet B (UVB) regions and another component beneficial to the skin. In these agents, specific protective and stabilizing effects are achieved, for example, by modified methylpyrrolidones, or by the addition of dextrin fatty acid esters, or by acrylic polymers with triazines. Documents such as US Patent No. 7,892,523 B2 describe the addition of plant extracts, or documents such as International Publication No. 2016 / 087948 A2 describe encapsulation into photosensitive capsules. It is also known that free radicals are generated in the skin and cells and cell components are destroyed by this highly reactive molecule in the visible and infrared spectral regions (Schroder et al., Skin Pharmacol Physiol. 2010;23(1):15-7). For this countermeasure, European Patent No. 2129357 proposes the use of a radical scavenger as a sunscreen in a mixture of UVA and UVB filters, seabuckthorn oil, special types of glass and minerals.

Summary of the Invention

Problems to be Solved by the Invention

[0003] The scientific community has hardly conducted research on a full range of sun protection.

Means for Solving the Problems

[0004] The object of the present invention is to provide a sunscreen and sunscreen agent for dark skin types that provides specific and effective protection from light rays in the entire spectral region of light, i.e., in the infrared, visible, and UV spectral regions. Another object of the present invention is to provide a composition that protects from infrared, visible, and UV light rays. Another object of the present invention is to provide a composition having good antioxidant properties. Another object of the present invention is to provide a composition containing a natural extract having good antioxidant properties. Another object of the present invention is to provide a prevention method that is specially designed for dark-skinned humans and is simultaneously effective for humans of all skin types. Another object of the present invention is the use of a sunscreen and sunscreen agent for dark skin types that provides a method for protecting the skin of dark-skinned humans from UV, infrared, and visible light rays in radiation.

Mode for Carrying Out the Invention

[0005] The first object of the present invention is a composition comprising or consisting of a mixture of the substances described below and having antioxidant and visible and near-infrared protection properties a) One or more UVA and UVB filter agents in the range of 5 to 24% by weight b) One or more pigments selected from the group consisting of rutile (titanium dioxide), zinc oxide, silicon oxide, zirconium oxide, aluminum oxide, and mixtures thereof, having different particle sizes in the micro and nano ranges, in the range of 2 to 30% by weight c) One or more coolants in the range of 0.1 to 20% by weight d) One or more radical scavengers selected from the group consisting of plants, plant extracts, vitamins, amino acids, flavonoids, carotenoids, α-hydroxy acids, and mixtures thereof, in the range of 0.1 to 48% by weight e) The balance up to 100% by weight of a cosmetic carrier, excipient, active substance, and mixtures thereof Here, each weight percentage is a percentage relative to the total weight of the composition.

[0006] Unexpectedly, the inventors have found that dark-colored humans, particularly those of light types IV-V, are more sensitive to visible and near-infrared light and, as a result, generate more ROS (reactive oxygen species) when exposed to radiation than humans with another light type.

[0007] In certain embodiments, the composition of the present invention comprises or consists of a mixture of the substances described below: a) one or more UVA and UVB filter agents in the range of 5 to 24% by weight b) one or more pigments selected from the group consisting of rutile (titanium dioxide), zinc oxide, silicon oxide, zirconium oxide, aluminum oxide, and mixtures thereof, having different particle sizes in the micro and nano ranges, in the range of 2 to 30% by weight c) one or more coolants in the range of 0.1 to 20% by weight d) one or more radical scavengers selected from the group consisting of plants, plant extracts, vitamins, amino acids, flavonoids, carotenoids, α-hydroxy acids, and mixtures thereof, in the range of 0.1 to 5% by weight e) the balance up to 100% by weight of a cosmetic carrier, excipient, active substance, or mixtures thereof Here, each weight percentage is a percentage relative to the total weight of the composition.

[0008] In certain embodiments, the composition of the present invention comprises or consists of a mixture of the substances described below: a) one or more UVA and UVB filter agents in the range of 5 to 24% by weight b) one or more pigments selected from the group consisting of rutile (titanium dioxide), zinc oxide, silicon oxide, zirconium oxide, aluminum oxide, and mixtures thereof, having different particle sizes in the micro and nano ranges, in the range of 3 to 6.5% by weight c) one or more coolants in the range of 0.5 to 4.5% by weight d) One or more radical scavengers selected from the group consisting of plants, plant extracts, vitamins, amino acids, flavonoids, carotenoids, α-hydroxy acids, and mixtures thereof, in an amount of 2 to 48% by weight e) The balance up to 100% by weight of a cosmetic carrier, excipient, active substance, or mixtures thereof Here, each percentage by weight is based on the total weight of the composition.

[0009] In certain embodiments, the composition of the present invention is a cosmetic sunscreen and sunblock composition.

[0010] In certain embodiments, the composition of the present invention is an anti-aging composition.

[0011] In certain embodiments, the composition of the present invention is an anti-dark spot composition.

[0012] In certain embodiments, the composition of the present invention is a composition having UVA and UVB in an amount of 5 to 24% by weight, particularly 5 to 7%, 7 to 10%, or 7 to 15%, 10 to 15%, 15 to 20%, 20 to 24% based on the total weight of the composition.

[0013] In certain embodiments, the composition of the present invention is a composition having a pigment in an amount of 2 to 30% by weight, particularly 2 to 3%, 3 to 6.5%, 6.5 to 7%, 7 to 10%, 10 to 15%, 15 to 20%, 20 to 25%, 25 to 30% based on the total weight of the composition.

[0014] In certain embodiments, the composition of the present invention is a composition having a coolant in an amount of 0.1 to 20% by weight, particularly 0.1 to 0.5%, 0.5 to 4.5%, 4.5 to 7%, 7 to 10%, 10 to 13%, 13 to 16%, 16 to 20% based on the total weight of the composition.

[0015] In certain embodiments, the composition of the present invention is a composition in which the radical scavenger has a weight percentage of 0.05 to 48%, 0.1 to 5%, particularly 0.05 to 0.1%, 0.1 to 0.5%, 0.5 to 1%, 1 to 2%, 2 to 5%, 5 to 10%, 10 to 15%, 15 to 20%, 20 to 30%, 30 to 40%, 40 to 48% based on the total weight of the composition.

[0016] In certain embodiments, the composition of the present invention comprises or consists of a mixture of the substances described below: a) One or more UVA and UVB filter agents in the range of 14.5% by weight b) One or more pigments selected from the group consisting of rutile (titanium dioxide), zinc oxide, silicon oxide, zirconium oxide, aluminum oxide, and mixtures thereof, having different particle sizes in the micro and nano ranges, in the range of 2 to 30% by weight c) One or more coolants in the range of 0.1 to 20% by weight d) One or more radical scavengers selected from the group consisting of plants, plant extracts, vitamins, amino acids, flavonoids, carotenoids, α-hydroxy acids, and mixtures thereof, in the range of 0.1 to 5% by weight e) The remainder up to 100% by weight of a cosmetic carrier, excipient, active substance, and mixtures thereof Here, each weight percentage is a percentage based on the total weight of the composition.

[0017] In certain embodiments, the composition of the present invention comprises or consists of a mixture of the substances described below a) One or more UVA and UVB filter agents in the range of 5 to 24% by weight b) 10.5% by weight of one or more pigments selected from the group consisting of rutile (titanium dioxide), zinc oxide, silicon oxide, zirconium oxide, aluminum oxide, and mixtures thereof, having different particle sizes in the micro and nano ranges c) One or more coolants in the range of 0.1 to 20% by weight d) One or more radical scavengers selected from the group consisting of plants, plant extracts, vitamins, amino acids, flavonoids, carotenoids, α-hydroxy acids, and mixtures thereof, in an amount of 0.1 to 5% by weight e) The balance up to 100% by weight of a cosmetic carrier, excipient, active substance, or mixtures thereof Here, each percentage by weight is based on the total weight of the composition.

[0018] In certain embodiments, the composition of the invention comprises or consists of a mixture of the substances described below: a) One or more UVA and UVB filter agents in the range of 5 to 24% by weight b) One or more pigments selected from the group consisting of rutile (titanium dioxide), zinc oxide, silicon oxide, zirconium oxide, aluminum oxide, and mixtures thereof, having different particle sizes in the micro and nano ranges, in an amount of 2 to 30% by weight c) One or more cooling agents in an amount of 16% by weight d) One or more radical scavengers selected from the group consisting of plants, plant extracts, vitamins, amino acids, flavonoids, carotenoids, α-hydroxy acids, and mixtures thereof, in an amount of 0.1 to 5% by weight e) The balance up to 100% by weight of a cosmetic carrier, excipient, active substance, or mixtures thereof Here, each percentage by weight is based on the total weight of the composition.

[0019] In certain embodiments, the composition of the invention comprises or consists of a mixture of the substances described below: a) One or more UVA and UVB filter agents in the range of 5 to 24% by weight b) One or more pigments selected from the group consisting of rutile (titanium dioxide), zinc oxide, silicon oxide, zirconium oxide, aluminum oxide, and mixtures thereof, having different particle sizes in the micro and nano ranges, in an amount of 2 to 30% by weight c) One or more cooling agents in an amount of 0.1 to 20% by weight d) One or more radical scavengers selected from the group consisting of plants, plant extracts, vitamins, amino acids, flavonoids, carotenoids, α-hydroxy acids, and mixtures thereof, in an amount of 0.18% by weight e) The balance up to 100% by weight of a cosmetic carrier, excipient, active substance, or mixtures thereof Here, each weight percentage is based on the total weight of the composition.

[0020] In certain embodiments, the composition of the present invention is used in combination with another anti-aging agent.

[0021] In certain embodiments, the composition of the present invention is used in combination with a whitening agent.

[0022] In certain embodiments, the composition of the present invention is used in combination with another anti-aging agent and a whitening agent.

[0023] In certain embodiments, the composition of the present invention has a UV filter agent that is bis-ethylhexyloxyphenol methoxyphenyl triazine, droxmetrizole trisiloxane, terephthalylidene dicamphor sulfonic acid, ethylhexyl triazone, butyl methoxydibenzoylmethane, diethylamino hydroxybenzoyl hexyl benzoate, diethylhexyl butamidotriazine, phenylbenzimidazole sulfonic acid, ethylhexyl methoxycinnamate, ethylhexyl salicylate, methylene bis-benzotriazolyl tetramethylbutylphenol, octocrylene, phenylbenzimidazole sulfonic acid, or a composition in which these are mixed.

[0024] In certain embodiments, the composition of the present invention has a pigment that is a mixture of TiO2 and ZnO with different particle sizes, where there are 2 to 5 parts by weight of TiO2 and 1 to 2 parts by weight of ZnO with a particle size of 100 to 500 μm, and further 12 to 24 parts by weight of TiO2 and 8 to 10 parts by weight of ZnO with a particle size of 10 to 600 μm.

[0025] In certain embodiments, the composition of the present invention has a pigment that is a mixture of nanoparticles and microparticles, and the weight ratio of the nanoparticles to the microparticles is 5:1 to 8:1.

[0026] In certain embodiments, the composition of the present invention has a small particle size in the range of 10 to 300 nm and a large particle size in the range of 100 to 250 μm.

[0027] In certain embodiments, the composition of the present invention has a pigment that is TiO2 with a particle size in the range of 10 to 600 nm.

[0028] In certain embodiments, the composition of the present invention has a pigment that is a mixture of TiO2 with a particle size of 10 to 600 nm and TiO2 with a particle size of 100 to 500 μm, and the weight ratio of the nanoparticles to the microparticles is 5:1 to 10:1.

[0029] In certain embodiments, the composition of the present invention has a pigment that is a mixture containing at least nanoparticles.

[0030] In certain embodiments, the composition of the present invention has a pigment that is a mixture of only nanoparticles.

[0031] In certain embodiments, the composition of the present invention contains or consists of a mixture of the substances described below: a) One or more UVA and UVB filter agents in the range of 12.5% by weight b) One or more pigments selected from the group consisting of rutile (titanium dioxide), zinc oxide, silicon oxide, zirconium oxide, aluminum oxide, and mixtures thereof, having different particle sizes in the micro and nano ranges, at 7.5% by weight c) One or more coolants at 15.1% by weight d) One or more radical scavengers selected from the group consisting of plants, plant extracts, vitamins, amino acids, flavonoids, carotenoids, α-hydroxy acids, and mixtures thereof, at 0.12% by weight e) The balance up to 100% by weight of a cosmetic carrier, excipient, active substance, and mixtures thereof Here, each weight percentage is a percentage relative to the total weight of the composition.

[0032] In certain embodiments, the composition of the invention comprises or consists of a mixture of the substances described below: a) One or more UVA and UVB filter agents in the range of 14.5% by weight b) One or more pigments selected from the group consisting of rutile (titanium dioxide), zinc oxide, silicon oxide, zirconium oxide, aluminum oxide, and mixtures thereof, having different particle sizes in the micro and nano ranges, at 10.5% by weight c) One or more coolants at 16% by weight d) One or more radical scavengers selected from the group consisting of plants, plant extracts, vitamins, amino acids, flavonoids, carotenoids, α-hydroxy acids, and mixtures thereof, at 0.18% by weight e) The balance up to 100% by weight of a cosmetic carrier, excipient, active substance, and mixtures thereof Here, each weight percentage is a percentage relative to the total weight of the composition.

[0033] In certain embodiments, the composition of the present invention is such that the coolant is L-menthyl glycerol ketal, DL-menthyl glycerol ketal, a mixture of these two, N-ethyl-p-menthane-3-carboxamide, menthol, isopulegol, monomethyl ン chill, 3-L-(menthyloxy)propane-1,2-diol, ethoxycarbonyl Nilmethyl lu-3-p-menthane carboxamide, essential oil of camphor, mint Essential oil , lavender Essential oil , and is a composition selected from the group consisting of mixtures thereof.

[0034] In certain embodiments, the composition of the present invention is a composition in which the radical scavenger has a radical defense index of 40 to 100,000 alone or in a mixture.

[0035] In certain embodiments, the composition of the present invention is a composition in which the radical scavenger has a radical defense index of 40 to 40,000 alone or in a mixture.

[0036] In certain embodiments, the composition of the present invention is a composition in which the radical scavenger has a radical defense index of 500 to 100,000 alone or in a mixture.

[0037] In certain embodiments, the composition of the present invention has a radical defense index of 20 to 4,000, preferably 900 to 3,600, particularly 1,100 to 3,000.

[0038] In certain embodiments, the composition of the present invention has a sun protection index of greater than 40, particularly 40 to 50+.

[0039] In certain embodiments, the composition of the present invention is a composition in which the radical scavenger is a hydrophilic compound.

[0040] In certain embodiments, the composition of the present invention has a radical scavenger which is roseroot (extract of the root of Rhodiola sacra, or extract of Rhodiola Rosea), Job's tear (extract of the seed of Coix Lacryma-Jobi), orchid (extract of the flower of Dendrobium nobile Lindl), Saussurea (extract of Saussurea involucrata), common marigold (extract of the flower of Calendula officinalis), peony (extract of the root of Paeonia lactiflora), Scutellaria (extract of the root of Scutellaria lateriflora, or extract of Scutellaria baicalensis), Salvia (extract of the root of Salvia miltiorrhiza), orchid (bre Tea composition selected from the group consisting of an extract of the root of Bletilla striata, green tea (extract of the leaves of Camellia sinensis), snowflake (extract of the bulbs of Leucojum aestivum), astragalus (extract of the roots of astragalus membranaceus), saposhnikovia (extract of the roots of saposhnikovia divaricata), albizia (extract of the flowers of albizia julibrissin), gastrodia (extract of the roots of gastrodia elata), an extract of magnolia seiboldii, tocopheryl acetate, and mixtures thereof.

[0041] In certain embodiments, the composition of the present invention is a composition in which the radical scavenger is a mixture of rodiola (extract of the roots of Rhodiola rosea), coix (extract of the seeds of Coix lacryma-jobi), dendrobium (extract of the flowers of Dendrobium nobile Lindl.), and green tea (extract of the leaves of Camellia sinensis).

[0042] In certain embodiments, the composition of the present invention is a composition in which the radical scavenger is a mixture of saussurea (extract of Saussurea involucrata), calendula (extract of the flowers of Calendula officinalis), peony (extract of the roots of Paeonia lactiflora), and green tea (extract of the leaves of Camellia sinensis).

[0043] In certain embodiments, the composition of the present invention is a composition in which the radical scavenger is scutellaria (extract of the roots of Scutellaria lateriflora), salvia (extract of the roots of Salvia miltiorrhiza), dendrobium (extract of the TeIt is a composition of a mixture of an extract of the root of Ilastriata and an extract of the leaves of Camellia sinensis (green tea).

[0044] In certain embodiments, the composition of the present invention is a composition in which the UV filter agents are ethylhexyl methoxycinnamate, diethylamino hydroxybenzoyl hexyl benzoate, bis-ethylhexyl oxy-phenol methoxyphenyl triazine, octocrylene, and phenylbenzimidazole sulfonic acid mixed together.

[0045] In certain embodiments, the composition of the present invention is a composition in which the pigments are titanium dioxide and zinc oxide mixed together.

[0046] In certain embodiments, the composition of the present invention is a composition in which the coolant is menthol.

[0047] In certain embodiments, the composition of the present invention is a mixture of radical scavengers including an extract of green tea, an extract of Scutellaria baicalensis, an extract of Saururus involucratus, an extract of the bulb of Leucojum aestivum, an extract of the root of Astragalus membranaceus, an extract of the root of Saposhnikovia divaricata, an extract of the flower of Calendula officinalis, an extract of the flower of Albizia julibrissin, and an extract of the root of Gastrodia elata.

[0048] In certain embodiments, the composition of the present invention has a UV filter agent that is a mixture of ethylhexyl methoxycinnamate, diethylamino hydroxybenzoyl hexyl benzoate, bis-ethylhexyloxyphenol methoxyphenyl triazine, octocrylene, and phenylbenzimidazole sulfonic acid; a pigment that is titanium dioxide and zinc oxide; a coolant that is menthol; and a radical scavenger that is a mixture of extracts of green tea, Scutellaria baicalensis, Saururus chinensis, bulbs of Leucojum aestivum, roots of Astragalus membranaceus, roots of Saposhnikovia divaricata, flowers of Calendula officinalis, flowers of Albizia julibrissin, and roots of Gastrodia elata.

[0049] In certain embodiments, the composition of the present invention is in the form of milk, gel, lotion, stick, water-in-oil emulsion John oil-in-water emulsion, or fluid emulsion.

[0050] The following list of gelling agents is used for the preparation of the different forms listed above: carbomer, xanthan, gum, carrageenan, guar gum and derivatives, cellulose derivatives, polyvinyl alcohol polyacrylate.

[0051] The composition of the present invention is stable at room temperature for at least 6 months, particularly for 6 months.

[0052] The term "room temperature" in the context of the present invention means from about 20°C to about 25°C.

[0053] The emulsions used in the cosmetics described above are, for example, addition products of ethylene oxide with linear C8-C 22 fatty alcohols and linear C 12 -C 22 fatty alcohols and C8-C 15 alkylphenols; addition products of ethylene oxide with glycerol having C 12 -C 22Mono fatty acids and diesters.

[0054] Another emulsion used in the cosmetic described above is, for example, an addition product of ethylene oxide with castor oil; C 12 -C 22 Esters of fatty acids and glycerol; polyglycerol, pentaerythritol, sugar alcohols (e.g., sorbitol), polyglucosides (e.g., cellulose); polyalkylene glycols; lanolin alcohol; copolymers of polysiloxane - polyalkyl polyether.

[0055] A second object of the present invention is the use of a mixture of substances described below as a sunscreen composition for preventing sunburn: a) One or more UVA and UVB filter agents in the range of 5 to 24% by weight b) One or more pigments selected from the group consisting of rutile (titanium dioxide), zinc oxide, silicon oxide, zirconium oxide, aluminum oxide, and mixtures thereof, having different particle sizes in the micro and nano ranges, in the range of 2 to 30% by weight c) One or more coolants in the range of 0.1 to 20% by weight d) One or more radical scavengers selected from the group consisting of plants, plant extracts, vitamins, amino acids, flavonoids, carotenoids, α - hydroxy acids, and mixtures thereof, in the range of 0.05 to 48% by weight e) The remaining proportion up to 100% by weight of a carrier, excipient, active substance, and mixtures thereof of a cosmetic for protecting the skin of humans with skin types IV and V Here, each weight percentage is a percentage relative to the total weight of the composition.

[0056] In a specific embodiment, it is the use of a mixture of substances described below as a sunscreen composition for preventing sunburn: a) One or more UVA and UVB filter agents in the range of 5 to 24% by weight b) One or more pigments selected from the group consisting of rutile (titanium dioxide), zinc oxide, silicon oxide, zirconium oxide, aluminum oxide, and mixtures thereof, having particle sizes different in the micro and nano ranges, in an amount of 2 to 30% by weight c) One or more coolants in an amount of 0.1 to 20% by weight d) One or more radical scavengers selected from the group consisting of plants, plant extracts, vitamins, amino acids, flavonoids, carotenoids, α-hydroxy acids, and mixtures thereof, in an amount of 0.1 to 5% by weight e) The balance up to 100% by weight of a cosmetic carrier, excipient, active substance, and mixtures thereof Here, each weight percentage is a percentage relative to the total weight of the composition.

[0057] In a particular embodiment, use as a sunscreen and sunscreen composition of a mixture of substances described below: a) One or more UVA and UVB filter agents in the range of 5 to 24% by weight b) One or more pigments selected from the group consisting of rutile (titanium dioxide), zinc oxide, silicon oxide, zirconium oxide, aluminum oxide, and mixtures thereof, having particle sizes different in the micro and nano ranges, in an amount of 3 to 6.5% by weight c) One or more coolants in an amount of 0.5 to 4.5% by weight d) One or more radical scavengers selected from the group consisting of plants, plant extracts, vitamins, amino acids, flavonoids, carotenoids, α-hydroxy acids, and mixtures thereof, in an amount of 2 to 48% by weight e) The balance up to 100% by weight of a cosmetic carrier, excipient, active substance, and mixtures thereof Here, each weight percentage is a percentage relative to the total weight of the composition.

[0058] A third object of the present invention is the use of a mixture of substances described below as an anti-aging composition: a) One or more UVA and UVB filter agents in the range of 5 to 24% by weight b) One or more pigments selected from the group consisting of rutile (titanium dioxide), zinc oxide, silicon oxide, zirconium oxide, aluminum oxide, and mixtures thereof, having different particle sizes in the micro and nano ranges, in the range of 2 to 30% by weight c) One or more coolants in the range of 0.1 to 20% by weight d) One or more radical scavengers selected from the group consisting of plants, plant extracts, vitamins, amino acids, flavonoids, carotenoids, α-hydroxy acids, and mixtures thereof, in the range of 0.05 to 48% by weight e) The remaining proportion up to 100% by weight of a cosmetic carrier, excipient, active substance, and mixtures thereof, for protecting the skin of humans with skin types IV and V Here, each weight percentage is a percentage relative to the total weight of the composition.

[0059] In certain embodiments, it is the use as an anti-aging composition of a mixture of the substances described below: a) One or more UVA and UVB filter agents in the range of 5 to 24% by weight b) One or more pigments selected from the group consisting of rutile (titanium dioxide), zinc oxide, silicon oxide, zirconium oxide, aluminum oxide, and mixtures thereof, having different particle sizes in the micro and nano ranges, in the range of 2 to 30% by weight c) One or more coolants in the range of 0.1 to 20% by weight d) One or more radical scavengers selected from the group consisting of plants, plant extracts, vitamins, amino acids, flavonoids, carotenoids, α-hydroxy acids, and mixtures thereof, in the range of 0.1 to 5% by weight e) The remaining proportion up to 100% by weight of a cosmetic carrier, excipient, active substance, and mixtures thereof Here, each weight percentage is a percentage relative to the total weight of the composition.

[0060] Use as an anti-aging composition of a mixture of substances described below in a specific embodiment: a) One or more UVA and UVB filter agents in the range of 5 to 24% by weight b) One or more pigments selected from the group consisting of rutile (titanium dioxide), zinc oxide, silicon oxide, zirconium oxide, aluminum oxide, and mixtures thereof, having different particle sizes in the micro and nano ranges, in the range of 3 to 6.5% by weight c) One or more coolants in the range of 0.5 to 4.5% by weight d) One or more radical scavengers selected from the group consisting of plants, plant extracts, vitamins, amino acids, flavonoids, carotenoids, α-hydroxy acids, and mixtures thereof, in the range of 2 to 48% by weight e) The remaining proportion up to 100% by weight of a cosmetic carrier, excipient, active substance, and mixtures thereof Here, each weight percentage is a percentage relative to the total weight of the composition.

[0061] Another object of the present invention is the use as an anti-dark spot composition of a mixture of substances described below: a) One or more UVA and UVB filter agents in the range of 5 to 24% by weight b) One or more pigments selected from the group consisting of rutile (titanium dioxide), zinc oxide, silicon oxide, zirconium oxide, aluminum oxide, and mixtures thereof, having different particle sizes in the micro and nano ranges, in the range of 2 to 30% by weight c) One or more coolants in the range of 0.1 to 20% by weight d) One or more radical scavengers selected from the group consisting of plants, plant extracts, vitamins, amino acids, flavonoids, carotenoids, α-hydroxy acids, and mixtures thereof, in the range of 0.05 to 48% by weight e) The remaining proportion up to 100% by weight of a cosmetic carrier, excipient, active substance, and mixtures thereof that protect the skin of humans with skin types IV and V Here, each weight percentage is a percentage relative to the total weight of the composition.

[0062] In certain embodiments, it is for use as an anti-dark spot composition of a mixture of substances described below: a) One or more UVA and UVB filter agents in the range of 5 to 24% by weight b) One or more pigments selected from the group consisting of rutile (titanium dioxide), zinc oxide, silicon oxide, zirconium oxide, aluminum oxide, and mixtures thereof, having different particle sizes in the micro and nano ranges, in the range of 2 to 30% by weight c) One or more coolants in the range of 0.1 to 20% by weight d) One or more radical scavengers selected from the group consisting of plants, plant extracts, vitamins, amino acids, flavonoids, carotenoids, α-hydroxy acids, and mixtures thereof, in the range of 0.1 to 5% by weight e) The remaining proportion up to 100% by weight of a cosmetic carrier, excipient, active substance, and mixtures thereof Here, each weight percentage is a percentage relative to the total weight of the composition.

[0063] In certain embodiments, it is for use as an anti-dark spot composition of a mixture of substances described below: a) One or more UVA and UVB filter agents in the range of 5 to 24% by weight b) One or more pigments selected from the group consisting of rutile (titanium dioxide), zinc oxide, silicon oxide, zirconium oxide, aluminum oxide, and mixtures thereof, having different particle sizes in the micro and nano ranges, in the range of 3 to 6.5% by weight c) One or more coolants in the range of 0.5 to 4.5% by weight d) One or more radical scavengers selected from the group consisting of plants, plant extracts, vitamins, amino acids, flavonoids, carotenoids, α-hydroxy acids, and mixtures thereof, in the range of 2 to 48% by weight e) The balance up to 100% by weight of the carrier, excipient, active substance, and mixtures thereof of the cosmetic Here, each weight percentage is a percentage relative to the total weight of the composition.

[0064] In certain embodiments, the compositions of the present invention are combined with another anti-aging agent.

[0065] In certain embodiments, the compositions of the present invention are combined with a whitening agent.

[0066] In certain embodiments, the compositions of the present invention are combined with another anti-aging agent and a whitening agent.

[0067] In certain embodiments, the pigment is a mixture of TiO2 and ZnO with large and small particle sizes, and there are 2 to 5 parts by weight of TiO2 and 1 to 2 parts by weight of ZnO with a particle size of 100 to 500 μm, and further 12 to 24 parts by weight of TiO2 and 8 to 10 parts by weight of ZnO with a particle size of 10 to 600 nm, which is the use of the present invention.

[0068] In certain embodiments, the radical scavenger is selected from the group consisting of Rhodiola rosea root extract, Coix lacryma-jobi seed extract, Dendrobium nobile Lindl. flower extract, Saururus chinensis extract, Calendula officinalis flower extract, Paeonia lactiflora root extract, Scutellaria lateriflora root extract, Salvia miltiorrhiza Bunge root extract, Bulbophyllum striatatum root extract, green tea (Camellia sinensis leaf extract), and mixtures thereof, which is the use of the present invention. Te The use of the present invention selected from the group consisting of these mixtures.

[0069] In certain embodiments, the use of the present invention wherein the UV filter agent is a mixture of ethylhexyl methoxycinnamate, diethylamino hydroxybenzoyl hexyl benzoate, bis-ethylhexyloxyphenol methoxyphenyl triazine, octocrylene, and phenylbenzimidazole sulfonic acid.

[0070] In certain embodiments, the use of the present invention wherein the pigment is a mixture of titanium dioxide and zinc oxide.

[0071] In certain embodiments, the use of the present invention wherein the coolant is menthol.

[0072] In certain embodiments, the use of the present invention wherein the radical scavenger is a mixture of extracts of green tea, Scutellaria baicalensis, Saururus chinensis, bulbs of Leucojum aestivum, roots of Astragalus membranaceus, roots of Saposhnikovia divaricata, flowers of Calendula officinalis, flowers of Albizia julibrissin, and roots of Gastrodia elata.

[0073] In certain embodiments, the use of the present invention wherein the UV filter agent is a mixture of ethylhexyl methoxycinnamate, diethylamino hydroxybenzoyl hexyl benzoate, bis-ethylhexyloxyphenol methoxyphenyl triazine, octocrylene, and phenylbenzimidazole sulfonic acid; the pigment is titanium dioxide and zinc oxide; the coolant is menthol; and the radical scavenger is a mixture of extracts of green tea, Scutellaria baicalensis, Saururus chinensis, bulbs of Leucojum aestivum, roots of Astragalus membranaceus, roots of Saposhnikovia divaricata, flowers of Calendula officinalis, flowers of Albizia julibrissin, and roots of Gastrodia elata.

[0074] Another object of the present invention is the composition of the present invention for use in protecting humans, particularly dark-skinned humans, and more particularly humans with skin types IV and V, against free radical-induced damage.

[0075] Another object of the present invention is a method of protecting human skin, particularly that of dark-skinned humans, and more particularly that of humans with skin types IV and V, from UV light, IR light, and visible light, with a sunburn prevention and sunscreen composition comprising a mixture of the substances described below: a) One or more UVA and UVB filter agents in the range of 5 to 24% by weight b) One or more pigments selected from the group consisting of rutile (titanium dioxide), zinc oxide, silicon oxide, zirconium oxide, aluminum oxide, and mixtures thereof, having different particle sizes in the micro and nano ranges, in the range of 2 to 30% by weight c) One or more coolants in the range of 0.1 to 20% by weight d) One or more radical scavengers selected from the group consisting of plants, plant extracts, vitamins, amino acids, flavonoids, carotenoids, α-hydroxy acids, and mixtures thereof, in the range of 0.05 to 48% by weight e) The remainder up to 100% by weight of a cosmetic carrier, excipient, active substance, and mixtures thereof Here, each weight percentage is a percentage relative to the total weight of the composition.

[0076] Another object of the present invention is a cosmetic treatment method comprising applying the composition of the present invention to the skin of humans, particularly dark-skinned humans, and more particularly humans with skin types IV and V.

[0077] The cosmetic sunburn prevention and sunscreen agent of the present invention comprises a mixture of the substances described below: a) One or more UVA and UVB filter agents in the range of 5 to 24% by weight b) 2 to 7% by weight of rutile (titanium dioxide), zinc oxide, silicon oxide, zirconium oxide, aluminum oxide, having different particle sizes in the micro and nano ranges, and one or more pigments selected from the group consisting of mixtures thereof c) 0.5 to 4.5% by weight of one or more coolants d) 2 to 48% by weight of one or more radical scavengers selected from the group consisting of plants, plant extracts, vitamins, amino acids, flavonoids, carotenoids, α-hydroxy acids, and mixtures thereof e) The balance up to 100% by weight of a cosmetic carrier, excipient, active substance, and mixtures thereof Here, each weight percentage is a percentage relative to the total weight of the composition.

[0078] It has been found that radical formation in dark-skinned humans is significantly higher in the IR radiation region compared to fair-skinned humans, and a special sunscreen is required.

[0079] Furthermore, a mixture of UV filter agents, coolants, pigments, and radical scavengers has been found to significantly improve sunburn prevention for skin types IV and V in the UV and IR regions, as well as in the visible light region (UV + IR + Vis), compared to conventional composition sunscreen agents. This fact is the same even when compared to conventional agents with a very high sun protection factor of SPF30 or 50. Now the important point here is not the number of filter agents, and the sun protection factor SPF is not increased either. In fact, the balance of UV filter agents, pigments, radical scavengers, and coolants is important.

[0080] Generally, the classification of skin types follows the von Luschan chromatic scale of types I to VI derived from the Fitzpatrick scale. Skin type I: The skin is very light, freckled, light eyes, and strawberry blond hair Skin type II: Fair skin, some freckles, light eyes, light-colored hair Skin type III: Medium-fair skin, light or hazel eyes, brown hair Skin type IV: Brown skin, brown eyes, dark brown to black hair Skin type V: Black skin, brown eyes, dark brown to black hair Skin type VI: Darkest brown skin, brown eyes, black hair In addition, see I. Moll (Ed.) Dermatologie, Thieme Verlag 2005 p. 534 ff.

[0081] UVA, UVB and / or broadband filter agents are used in the present invention. These are, for example, butyl methoxydibenzoylmethane, 3-benzylidenecamphor, sulfonic acid derivatives thereof, octyl dimethyl PABA, homosalate, octisalate, benzophenone-3, benzophenone-4, and mixtures thereof.

[0082] UV filter agents with low allergenic potential and no hormonal side effects are particularly preferred. Advantageously usable are two or more of the following mixtures: bis-ethylhexyl oxy-phenol methoxyphenyl triazine (Tinosorb S®), drometrizole trisiloxane (Mexoryl XL®), terephthalylidene dicamphor sulfonic acid (Mexoryl SX®), ethylhexyl triazone (Uvinul T 150®), butyl methoxydibenzoylmethane (Avobenzone®), diethylamino hydroxybenzoyl hexyl benzoate (Uvinul A Plus®), diethylhexyl butamido triazone (Iscotrizinol®), phenylbenzimidazole sulfonic acid (Enzulisol®).

[0083] Mineral filters such as oxides of Ti, Si, Zn, Fe(III), Zr, Al, Mn, etc. that can be used in a mixture together with a chemical filter are also preferred. The particle size ranges up to 500 μm, but particularly preferably in the range of 200 - 800 nm.

[0084] Used as a pigment and particularly due to its reflection behavior, the mineral filter of the present invention serves two purposes. In certain embodiments, from this, a mixture of particles in the range of 100 - 500 μm and particles in the range of 400 - 800 nm of the same or different pigments is used at a ratio of 1:8 to 1:20 (ratio of large particle size to small particle size).

[0085] Due to the difference in particle size, a significantly improved overall reflection behavior of the pigment has been found. This is because the reflection in the UV and visible regions decreases with an increase in particle size, while the reflection increases in the infrared region. In addition, when pigments with significantly different refractive indices are used, for example rutile n = 2.8 and ZnO n = 2.10, the reflection also increases.

[0086] From this, a preferred pigment is a mixture of TiO2 and ZnO in large and small sizes. Preferably, such a pigment is a pigment mixture of TiO2 and ZnO, with 2 - 5 parts by weight of TiO2 and 1 - 2 parts by weight of ZnO present, and the particle sizes of these are 200 - 500 μm, and further 12 - 24 parts by weight of TiO2 or 8 - 10 parts by weight of ZnO are present, and the particle sizes of these are 400 - 600 nm. In particular, this is, for example, a mixture of 2 parts by weight of TiO2 with a particle size of 200 - 500 μm and 1 part by weight of ZnO, and 12 parts by weight of TiO2 with a particle size of 400 - 600 nm and 8 parts by weight of ZnO. This prevents the main part of the overall radiation penetrating the skin and significantly improves the effectiveness of sunscreen preparation. Preferably, the presence of the pigment is in the range of 3 - 6.0 wt%, particularly in the range of 3.5 - 5.5 wt%.

[0087] A particularly preferred filter mixture is a mixture of TiO2 and ZnO with pigments of various sizes, where there are 2 to 5 parts by weight of TiO2 and 1 to 2 parts by weight of ZnO, with particle sizes of these being 200 to 500 μm, and further there are 12 to 24 parts by weight of TiO2 or 8 to 10 parts by weight of ZnO, with particle sizes of these being 400 to 600 nm, and butyl methoxydibenzoylmethane and bis-ethylhexyl oxy-phenol methoxyphenyl triazine are in the range of weight ratio 1:2.2 - 2.8:0.8 - 1.1 (ratio of pigment to filter) and consist of TiO2 / ZnO as the corresponding pigment.

[0088] In another embodiment of the present invention, the pigment is TiO2 with a particle size in the range of 200 to 600 nm, but particularly a mixture of TiO2 with a particle size of 200 to 600 nm and TiO2 with a particle size of 100 to 500 μm, and the nanoparticles and microparticles are present in a weight ratio of 5 to 10:1.

[0089] Preferred radical scavengers are plants and parts of plants, particularly plant extracts. Preferred plant extracts include tannic acid, rosemary oil, extracts of rosemary, extracts of green tea, extracts of grapefruit, extracts of curry, extracts of acerola, extracts of the skin of aronia, extracts of coffee beans, extracts of the roots of angelica, and in addition to these, extracts of the following plants: extracts of the roots of Rhodiola rosea, extracts of the seeds of Coix lacryma-jobi, extracts of the flowers of Dendrobium nobile Lindl., extracts of Saururus involucratus, extracts of the flowers of Calendula officinalis, extracts of the roots of Paeonia lactiflora, extracts of the roots of Scutellaria lateriflora, extracts of the roots of Salvia miltiorrhiza, extracts of the roots of Bulbophyllum striatum. Te are included.

[0090] According to a preferred embodiment of the present invention, the radical scavenger is a mixture of Iwabenkei (extract of the roots of Rhodiola rosea), Juzudama (extract of the seeds of Coix lacryma-jobi), Ran (extract of the flowers of Dendrobium nobile Lindl), and green tea (extract of the leaves of Camellia sinensis). According to another preferred embodiment of the present invention, the radical scavenger is a mixture of Touhirene (extract of Saururus involucratus), Kinsenka (extract of the flowers of Calendula officinalis), Button (extract of the roots of Paeonia lactiflora), and green tea (extract of the leaves of Camellia sinensis). According to a third preferred embodiment of the present invention, the radical scavenger is a mixture of Tatsunamisou (extract of the roots of Scutellaria lateriflora), Salvia (extract of the roots of Salvia miltiorrhiza), Ran (extract of the roots of Te Bleilla striata), and green tea (extract of the leaves of Camellia sinensis). Regarding the radical scavengers of these three preferred embodiments, the distribution in each mixture is approximately equal, that is, 1:1:1. Preferably, the radical scavenger of the preferred embodiment is present at 2 to 12 wt% based on the weight of the sunscreen and sunscreen agent.

[0091] The plant extract is prepared by extracting fresh or dried plants or parts of plants with water or water / glycerol at a temperature of 15 to 35 °C.

[0092] Another preferred radical scavenger is a vitamin, such as vitamin C, vitamin B, vitamin A, SOD (superoxide dismutase).

[0093] In order to be effective as envisioned by the present invention, the radical scavenger has a radical defense index of 500 to 100,000, either alone or in a mixture.

[0094] The Radical Protection Factor (RPF) is a value indicating the radical scavenging activity of a substance or product containing an antioxidant. For example, this value is measured using a MiniScope MS400 X-band EPR spectrometer manufactured by Magnettech (Berlin, Germany). The standard material DPPH (2,2-diphenyl-1-piperidylhydrazyl) (Sigma Aldrich, St. Louis, USA) is measured at 1 mM DPPH in ethanol using a Bruker Elexsys E500 X-band EPR spectrometer manufactured by BioSpin GmbH (Karlsruhe, Germany). The RPF measurement is carried out at a constant temperature in the range of 25 to 50 °C for the standard material of 1 mM DPPH with the assistance of the "MiniScopeControl 6.51.exe" software for the following measurement parameters: BO field: 3350.84 G; Sweep: 95.25 G; Sweep time: 20 s; Modulation: 2000 mG; MW atten: 15 dB; Gain: 1; E: 2; Smooth: 0.10 s; Step: 4086. The sophisticated measurement method is described in Photochemistry and Photobiology, 2011, 87:452-456 by Meineke et al. The number of reduced test radicals represents the radical scavenging activity normalized to the measured product or antioxidant with a radical scavenging activity of 1 mg. The RPF is calculated by the following formula

[0095] RPF = RC × RF / PI

[0096] Here, RC is the concentration of the test radical (radicals per mg); RF is the reduction factor determined by the difference between the intensity of the untreated test radical and the decreased signal intensity after treatment with the antioxidant or product, normalized to the signal of the treated test radical; PI is the product input amount expressed as the amount of the measured product or substance (antioxidant) (mg / ml).

[0097] Let N be a positive number. RPF is the number of free radicals per mg multiplied by 10 to the 14th power, and RPF = N x [10 to the 14th power radicals per mg]. As often described in this specification, generally this value is used in the literature without multiplying by 10 to the 14th power.

[0098] The sunburn prevention and sunscreen agents of the present invention also contain a cooling component. Instead of an actual coolant, a moisturizing agent in the form of a plant extract is partially used. However, L-menthyl glycerol ketal (FEMA GRAS 3807), DL-menthyl glycerol ketal (FEMA GRAS 3808), a mixture of these two, N-ethyl-p-menthane carboxamide (WS-5), menthol, isopulegol, Monomethyl glutarate, 3 -L-(menthyloxy)propane-1,2-diol (MPD), ethoxycarbo Nilmethyl yl-3-p-menthane carboxamide (WS-5), essential oil of camphor, mint Essential oil , lavender Essential oil When using a normal coolant selected from the group consisting of these mixtures, the cooling effect is improved.

[0099] Adding cold cream with borax as an emulsifier can also utilize the cooling effect of water.

[0100] The radical defense index of the formulated sunburn prevention and sunscreen agents of the present invention is in the range of 100 to 4,000, preferably 900 to 3,600, and particularly in the range of 1,100 to 3,000.

[0101] The sunburn prevention and sunscreen agents of the present invention can be prepared as O / W emulsion John or as W / O emulsion John For this purpose, known emulsions John are used. For example, O / W emulsion John is a C12-C22 monofatty acid and diester of an absorption product of 1 to 30 moles of ethylene oxide with glycerol, and for example, W / O emulsion JohnIt includes polyglycerol, pentaerythritol, and polyethylene glycol, which are absorption products of 2 to 15 mol of ethylene oxide with castor oil.

[0102] The agent of the present invention also contains cosmetic excipients and carriers as normally used in the preparation, such as water, preservatives, dyes, thickeners, plasticizing substances, moisturizing substances, fragrances, alcohols, polyols, electrolytes, polar and nonpolar oils, polymers, copolymers, emulsifiers, and / or stabilizers.

[0103] The oil used in the present invention is a conventional cosmetic oil such as mineral oil, hydrogenated polyisobutene (INCI name: Hydrogenated Polyisobutene), synthetic squalane or squalane prepared from natural products (INCI name: Squalane, Synthesqual®, Cosbiol®), branched or unbranched, saturated or unsaturated cosmetic esters, vegetable oils, or a mixture of two or more of these.

[0104] Particularly preferred oils are, for example, hydrogenated polyisobutene, polyisoprene, squalane, tritridecyl trimellitate, trimethylpropane - triisostearate, isodecyl citrate, neopentyl glycol - diheptanoate, PPG - 15 stearyl, calendula oil, jojoba oil, avocado oil, macadamia nut oil, and mixtures thereof. Cosmetic properties of solid preparations such as transparency, softness, hardness, and spreading effect are affected by the oil selected.

[0105] The cosmetic sunscreen and sunblock agent of the present invention can be used as a sunscreen cream, sunscreen gel, sunscreen lotion, sunscreen spray, and sunscreen milk. These products are prepared by methods well known to those skilled in the art.

[0106] The object of the present invention is also the use of the above - described substances as sunscreen and sunblock agents.

[0107] A further object of the present invention is a method of protecting dark human skin from UV, infrared, and visible light using the sunscreen and sunburn prevention agents described above.

[0108] The generation of radicals in subjects with different skin qualities was analyzed by comparative analysis. In this test, subjects with skin types I to III were compared with subjects with skin types IV to V. This test showed that subjects with light skin colors (skin types I to III) in the ultraviolet spectral region generate significantly more radicals in their skin due to solar radiation. On the other hand, in subjects with skin types IV to V, the generation of radicals was shown to be significantly lower. This can be understood because dark skin color is a protective system, similar to the system in which subjects with light skin colors turn brown.

[0109] Subjects with light and dark skin colors show little difference in the visible spectral region, while dark-skinned subjects show significantly higher radical generation in the infrared spectral region compared to fair-skinned subjects. This is more than twice that of fair-skinned subjects.

[0110] Considering that more than 50% of solar radiation reaches the skin in the infrared spectral region (thermal radiation), effective preventive measures must be clearly provided for this region as well. Regarding the explanation of this effect, since dark-skinned subjects absorb more infrared rays, that is, thermal radiation, the skin temperature of dark-skinned subjects is higher than that of fair-skinned subjects.

[0111] All numbers in percentages or parts in the specification are by weight ratio.

Brief Description of the Drawings

[0112]

Figure 1

Figure 2

Figure 3

[0113] Here, the present invention will be described in detail using examples.

Examples

[0114] Example 1 Sunburn prevention and sunscreen formulation I Separate phases A, B, and C are prepared. Phases A and B are stirred together at 75 °C and homogenized at this temperature at 3,000 rpm for 15 minutes. When the temperature has dropped to 40 °C, phase C is added during stirring and stirring is continued for a few more minutes. The phase compositions are as described below in wt% units. Phase A: Water up to 100%, propylene glycol 2.2, acrylate crosspolymer 0.5, xanthan gum 0.3. Phase B: Ethylhexyl methoxycinnamate 5.0, Tinosorb M® (methylenebisbenzotriazolyltetramethylbutylphenol) 3.0, TiO2 4.0 (100 - 200 nm), TiO2 0.8 (200 - 300 μm), ZnO 1.0 (100 - 200 nm), ZnO 0.2 (100 - 150 μm), ethylhexyl salicylate 4.0, butyl methoxydibenzoylmethane 3.0, dicaprylyl carbonate 6.0. Phase C: Colhibin® (hydrolyzed rice protein) 0.5, antioxidant extract 4.5 (a mixture of Shitan (extract of the root of Rhodiola rosea), Juzudama (extract of the seed of Coix lacryma-jobi), Ran (extract of the flower of Dendrobium nobile Lindl.), and green tea (extract of the leaves of Camellia sinensis)), isopulegol 2.0, soy protein 0.7, preservative 0.8, fragrance 0.8.

[0115] Example 2 Sunburn prevention and sunscreen formulation II The preparation is similar to that of Example 1. The phase compositions are as described below in wt% units. Phase A: Water up to 100%, propylene glycol 2.0, acrylate crosspolymer 0.6, guar gum 0.4. Phase B: Mexoryl® XL (drometrizole trisiloxane) 2.0, Mexoryl® S (terephthalylidene dicamphorsulfonic acid) 1.0, Uvinul® T150 (ethylhexyl triazone) 2.0, Uvinul® A+ (diethylamino hydroxybenzoyl hexyl benzoate) 2.8, TiO2 3.4 (100 - 200 nm), TiO2 0.4 (200 - 300 μm), ZnO 0.4 (100 - 200 nm), ZnO 0.1 (100 - 150 μm), dicaprylyl carbonate 5.5. Phase C: Colhibin® (hydrolyzed rice protein) 0.6, antioxidant extract 4.5 (a mixture of Touhirei (extract of Saururus involucratus), Kinsenka (extract of the flower of Calendula officinalis), Botan (extract of the root of Paeonia lactiflora), and green tea (extract of the leaves of Camellia sinensis)), glycerol 2.0, menthol 1.0, rice protein 0.9, preservative 0.8, fragrance 0.5.

[0116] Example 3 Sunburn prevention and sunscreen formulation III The preparation is similar to that of Example 1. The phase compositions are as described below in wt% units. Phase A: Water up to 100%, Propylene Glycol 2.1, Acrylate Crosspolymer 0.6, Guar Gum 0.4. Phase B: Mexoryl® SX (Terephthalylidene Dicamphor Sulfonic Acid) 2.0, Uvinul® T150 (Ethylhexyl Triazone) 1.0, Avobenzone (Butyl Methoxydibenzoylmethane) 2.5, Enzulisol (Phenylbenzimidazole Sulfonic Acid) 1.6, TiO2 4.3 (100 to 300 nm), TiO2 0.6 (200 to 250 μm), (Phenylbenzimidazole Sulfonic Acid) 5.0. Phase C: Colhibin® (Hydrolyzed Rice Protein) 0.5, Antioxidant Extract 4.5 (a mixture of Scutellaria lateriflora root extract, Salvia miltiorrhiza root extract, Bulbocodium striata root extract, and Camellia sinensis leaf extract), N-Ethyl-3-p-mentanecarboxamide 2.0, Urea 6.0, Soybean Protein 0.9, Preservative 0.7, Fragrance 0.9. Te Example 4: Comparative Example

[0117] Apply sunscreen cream I to the skin area of about 20 cm to 10 subjects with black skin type V. Apply sunscreen cream II to an area of the same size. This application amount corresponds to the standard amount of 2 mg / cm 2 . Expose both areas to IR radiation at an intensity of 70 mW / cm 2 for 15 minutes using a LOT QuantumDesign solar simulator. After a 5-minute break, measure the number of radicals generated using the RPF method described above. 2

[0118] ​Sunblock Cream I (Commercial): UV filters Mexoryl® XL 2.0, Mexoryl® SX 1.0, Uvinul® T150 2.0, Uvinul® A+ 2.80, TiO2 2.0 (100 - 200 nm); radical scavenger tocopheryl acetate 0.8; other common adjunct substances.

[0119] Sunblock Cream II: The composition described in Example 2

[0120] A significant decrease in the number of free radicals on the skin is observed with the sunblock cream II of the present invention.

[0121] Upon irradiation with either a solar simulator or that of a water-filtered IR lamp, untreated skin shows high radical generation in skin types I - III. Radical generation in the V region is three times higher (radical generation = 0.4 relative units) than that of skin type V (radical generation = 0.12 relative units). However, when looking at the near-infrared wavelength region, radical generation is more than twice as high in darker skin compared to fair skin.

[0122] Tests have shown that the application of commercial Sunblock Cream I in the UV region reduces radical generation in fair skin to 0.01 relative units or less by the UV filter. The same application was also performed on darker skin. The reduction in radical generation in both skin types in the near-infrared region is slight compared to untreated skin. Radical generation in the near-infrared region is 0.18 relative units (10% reduction) in fair skin and 0.36 relative units (10% reduction) in darker skin.

[0123] When the sunscreen cream II of the present invention is applied to the skin, good protection is proven even in the UV region. However, a significant decrease in radical generation is also observed in the infrared spectral region. In fair skin, the radical generation value decreases to 0.0028 relative units (86% decrease), and in light brown skin, it decreases to 0.0036 relative units (91% decrease). Skin temperature is measured with a non-contact IR thermometer before and after irradiation, and the value after application of the sunscreen cream II is less than 40°C.

[0124] Irradiation in the near-infrared region was carried out with a water-filtered IR lamp in the spectral region of 600 - 1,400 nm.

[0125] Example 5 The cream formulations LC and LC1 were examined. Composition:

[0126] [Table 1]

[0127] [Table 2]

[0128] [Table 3]

[0129] Preparation of the composition: Phases A, B, and E are prepared separately, heated to 70°C, and carefully mixed with stirring to emulsify the mixture. When cooled to 30 - 35°C, phases C and D are added.

[0130] Measurement of the sun protection factor (SPF) of LC1: The SPF of 44 was measured for the formulation LC1 according to the guidelines (ISO 24444).

[0131] Example 5-1: Determination of the radical protection factor (RPF) in vitro Method: The principle of the RPF technique is the measurement of the radical scavenging activity of substances / products containing antioxidants (T. Herrling, L. Zastrow, and N. Groth, "Classification of cosmetic products - The Radical Protection Factor (RPF)," S TM FW-Journal 5(124), 282-284 (1998).). This test is carried out by EPR spectroscopy using test radicals reduced by the antioxidant system. The number of reduced test radicals represents the radical scavenging activity normalized to 1 mg of antioxidant substance / product. The RPF is calculated by the following equation (1):

[0132] RPF = RC × RF / PI (1) RC = Concentration of test radicals [radicals / ml] RF = Reduction factor, which represents the difference between the intensity of the untreated test radicals and the reduced signal intensity after treatment with the antioxidant, normalized to the signal of the untreated test radicals. PI = Product input amount, which represents the amount of substance / product measured in [mg / ml].[[]]END]] The RPF is expressed as a positive number N using the measurement unit of 14 radicals / mg, and RPF = N· 14 radicals / mg).

[0133] For RPF analysis, an X-band EPR spectrometer (MS5000, Magnettech GmbH by Freiberg Instruments GmbH, Freiberg, Germany) was used to analyze the reduction of the test radical 2,2-diphenyl-1-picrylhydrazyl (DPPH) (Sigma-Aldrich, Steinheim, Germany) by the antioxidant system. The spin concentration of the 1 mM ethanol DPPH solution was calculated using the X-band EPR spectrometer (Bruker Elexsys E500, Karlsruhe, Germany) manufactured by Bruker BioSpin GmbH described above. The analysis of EPR data was performed using Bruker device control software Xepr (Bruker Biospin, Karlsruhe, Germany). Spin quantification was performed according to the procedure described in the Xepr manual (Bruker Biospin, Karlsruhe, Germany). The absolute spin concentration and spin amount were calculated three times. For the RPF analysis of the sample, a 500 mg formulation was solubilized in 10 mL of ethanol and further diluted (1:1) with a 1 mM DPPH ethanol solution of known spin concentration. The sample was stored at room temperature with constant panning in a dark room. The measurements were performed after incubation of the sample, after sample preparation (0 h) and 23 - 28 h after the DPPH signal stabilized. The calculation of the RPF value was performed using the EPR software "ESR Studio" (Freiberg Instruments GmbH, Freiberg, Germany) and the Microsoft Excel 2016 (Microsoft Office 2016)) calculation program.

[0134] Results:

[0135]

Table 4

[0136] LC and LC1 show good RPF values.

[0137] Example 5-2: Evaluation of Optical Properties (in vitro) Method: The optical parameters μ a and μ s ’ were calculated by inverse Monte Carlo simulation (iMCS) (reference: M. Friebel et al., "Determination of optical properties of human blood in the spectral range 250 to 1100 nm using Monte Carlo simulations with hematocrit-dependent effective scattering phase function," Journal of Biomedical Optics 11(3), (2006)). Based on a given phase function and experimental measurements of reflection and transmission (R t M and T t M ), iMCS repeatedly uses forward Monte Carlo simulation for the calculation of the optical parameters μ a and μ s ’. iMCS calculates the simulated reflectance and transmittance values R a and μ s ‘ obtained using an initial set of μ t S and T t S . These values are then compared with the experimentally measured R t M and T t M values. Through systematic variation of μ a and μ s ’, the deviation of the simulated R t S and T t S values from the measured values is minimized until a set of optical parameters is found within an error threshold of 0.20% deviation. For the refractive index related to the formulation, the value of water is used, and isotropic scattering is used for μs was calculated. Sunscreen formulations LC and LC1 were studied.

[0138] Results: Two creams, LC and LC1, were prepared twice, and each sample was measured three times. The spectra of each sample were averaged and simulated depending thereon. Cream LC shows a medium scattering parameter that decreases as the wavelength increases, and cream LC1 shows a doubling of the scattering characteristics (see Figure 1).

[0139] Example 5-3: Radical generation after VIS / NIR irradiation (ex vivo) Method: EPR study: Prevention of radical generation in the VIS / NIR spectral region

[0140] Sample preparation and EPR measurement Using the EPR technique, spin marker PCA (3-carboxy-2,2,5,5-tetramethylpyrrolidine-1-oxy) can be used to measure free radicals in the skin induced by exogenous stressors such as irradiation. This method can show that different spectral regions tend to have strong radical generation in vivo and ex vivo. Ultraviolet light promotes the strongest radical generation and is further irradiated with VIS and NIR. UV is involved in at least 50% of ROS generation, and the remaining radicals are generated by VIS / NIR radiation. In this test, porcine ear skin, an appropriate model for human skin, was used to analyze the radical protection effects of two sunscreen formulations (LC and LC1). X-band EPR is an appropriate and reproducible technique for the analysis of skin samples under or without irradiation in an easy-to-understand form. This method has been established and has already been described in the literature (C. Souza et al., "Radical-Scavenging Activity of a Sunscreen Enriched by Antioxidants Providing Protection in the Whole Solar Spectral Range," Skin Pharmacol Physiol 30(2), 81-89 (2017)). For the examination of various cream formulations, 2.0 mg / cm 2 was uniformly distributed on the skin surface while massaging for 2 minutes according to the COLIPA standard procedure (Rehaforum Medical GmbH, Elmshorn, Germany). The EPR study was carried out 30 minutes after application. Skin biopsies were processed as described above and further subjected to EPR study.

[0141] For the evaluation, the signal amplitude of PCA was measured from each spectrum using the evaluation software "ESR Studio". Since the amount of PCA does not change the linearity of the EPR spectrum during the measurement time, it is derived from the signal height of the center line of the spectrum. For the calculation of radical generation, the EPR intensity of the irradiated sample was subtracted from that of the non-irradiated sample. Also, irradiated and non-irradiated control biopsies without applying the cream were analyzed. Each experiment was repeated twice for 6 pig ears.

[0142] Results: LC1 reduces radical generation in the skin by 53% compared to untreated skin, and LC reduces it by 28% (see Figure 2).

[0143] Example 5-4 Method: Measurement of the effect of NIR irradiation on the antioxidant network of the skin To analyze the NIR protection of the sunscreen formulations LC and LC1, the carotenoid concentration in the skin in vivo was measured by resonance Raman spectroscopy (RRS). Two skin areas of six female volunteers were analyzed for carotenoid concentration (skin types IV-V according to the Fitzpatrick scale (T. B. Fitzpatrick, "The Validity and Practicality of Sun-Reactive Skin Type-I Through Type-Vi," Arch.Dermatol. 124(6), 869-871 (1988))). One skin area was left untreated and the other area was evenly treated with each of the cream formulations LC and LC1 (according to the COLIPA standard procedure). Carotenoid concentration was measured after a 30-minute penetration time before irradiation and 60 minutes after NIR irradiation. The irradiance was 60 mW / cm 2 and was applied for 30 minutes.

[0144] Results: To analyze the protective effects of the cream formulations LC and LC1 in the NIR-irradiated area with respect to the antioxidant status, carotenoid concentration was examined non-invasively in vivo by resonance Raman spectroscopy (see Figure 3). Previous studies have shown that carotenoid concentration acts as an indicator component of the antioxidant status of human skin.

[0145] In untreated skin, the carotenoid concentration decreases after 60 minutes of NIR irradiation. In contrast to this result, the application of the cream formulations LC and LC1 promotes a significant increase in carotenoid concentration in each of both cases (p ≤ 0.05, see Figure 3). From this, not only is the antioxidant status stabilized, but the antioxidant status is also improved. This result clearly shows that the sunscreen formulations LC and LC1 provide good radical defense in the NIR-irradiated area and LC1 slightly more strongly supports the antioxidant network. NIR irradiation decreases the carotenoid concentration in the skin. The antioxidants contained within the cream formulations support the antioxidant network and show an effective enhancement of the skin's antioxidants by the topical application of the newly developed sunscreen formulations.

[0146] Example 6: Example of a sunscreen milk formulation

[0147]

Table 5

[0148] Example 7: Example of Sunscreen Gel Formulation

[0149]

Table 6

[0150] Example 8: Example of Sunscreen Lotion Formulation

[0151]

Table 7

[0152] Example 9: RPF Evaluation The following samples were evaluated for ROS (reactive oxygen species) generation by the method described above: · 1% menthol · The following mixture of antioxidants used in the LC1 composition: extract of the root of Scutellaria baicalensis, extract of Saururus involucratus, extract of the bulb of Leucojum aestivum, extract of green tea · The combination of the above-described mixture of antioxidants and 1% menthol In this way, the synergistic effect of the composition components is obtained.

[0153] Example 10: RPF Evaluation The following samples were evaluated for ROS generation by the method described above: · Composition LC1 · Composition LC1 without 1% menthol In this way, the synergistic effect of the composition components is obtained.

Claims

1. A composition comprising or consisting of a mixture of the substances described below, having antioxidant and visible and near-infrared protection properties: a) A UVA and UVB filter agent in the range of 5 to 24% by weight b) One or more pigments selected from the group consisting of rutile (titanium dioxide), zinc oxide, silicon oxide, zirconium oxide, and aluminum oxide, in the range of 2 to 30% by weight, said pigment being a mixture of nanoparticles and microparticles c) One or more coolants selected from the group consisting of L-menthyl glycerol ketal, DL-menthyl glycerol ketal, a mixture of these two, N-ethyl-p-menthane-3-carboxamide, menthol, isopulegol, monomethyl glutarate, 3-L-(menthyloxy)propane-1,2-diol, ethoxycarbonylmethyl-3-p-menthane carboxamide, essential oil of camphor, essential oil of mint, and essential oil of lavender, in the range of 0.5 to 4.5% by weight d) One or more radical scavengers selected from the group consisting of extracts of the roots of Rhodiola sakura or Rhodiola rosea, extracts of the seeds of Coix lacryma-jobi, extracts of the flowers of Dendrobium nobile Lindl, extracts of Saururus involucrata, extracts of the flowers of Calendula officinalis, extracts of the roots of Paeonia lactiflora, extracts of the roots of Scutellaria lateriflora, extracts of the roots of Scutellaria baicalensis, extracts of the roots of Salvia miltiorrhiza, extracts of the roots of Bletilla striata, extracts of the leaves of Camellia sinensis, extracts of the bulbs of Leucojum aestivum, extracts of the roots of Astragalus membranaceus, extracts of the roots of Saposhnikovia divaricata, extracts of the flowers of Albizia julibrissin, extracts of the roots of Gastrodia elata, extracts of Magnolia sieboldii, and tocopheryl acetate, in the range of 1 to 10% by weight, and e) Up to 100% by weight of a cosmetic carrier, excipient, and active substance Here, each weight percentage is based on the total weight of the composition. **Claim 2** The composition according to claim 1, comprising or consisting of a mixture of the substances described below: a) UVA and UVB filter agents in the range of 5 to 24% by weight b) One or more pigments selected from the group consisting of rutile (titanium dioxide), zinc oxide, silicon oxide, zirconium oxide, and aluminum oxide, in the range of 2 to 30% by weight, said pigments being a mixture of nanometer-sized particles and micrometer-sized particles c) One or more coolants selected from the group consisting of L-menthyl glycerol ketal, DL-menthyl glycerol ketal, a mixture of these two, N-ethyl-p-menthane-3-carboxamide, menthol, isopulegol, monomethyl glutarate, 3-L-(menthyloxy)propane-1,2-diol, ethoxycarbonylmethyl-3-p-menthane carboxamide, essential oil of camphor, essential oil of mint, and essential oil of lavender, in the range of 0.5 to 4.5% by weight d) One or more radical scavengers selected from the group consisting of extract of the root of Rhodiola sakura or Rhodiola rosea, extract of the seed of Coix lacryma-jobi, extract of the flower of Dendrobium nobile Lindl, extract of Saururus involucratus, extract of the flower of Calendula officinalis, extract of the root of Paeonia lactiflora, extract of the root of Scutellaria lateriflora, extract of the root of Scutellaria baicalensis, extract of the root of Salvia miltiorrhiza, extract of the root of Bletilla striata, extract of the leaf of Camellia sinensis, extract of the bulb of Leucojum aestivum, extract of the root of Astragalus membranaceus, extract of the root of Saposhnikovia divaricata, extract of the flower of Albizia julibrissin, extract of the root of Gastrodia elata, extract of Magnolia sieboldii, and tocopheryl acetate, in the range of 1 to 5% by weight e) Up to 100% by weight of a cosmetic carrier, excipient, and active substance Here, each weight percentage is based on the total weight of the composition.

3. The composition according to claim 1, comprising or consisting of a mixture of the substances described below: a) UVA and UVB filter agents in the range of 5 to 24% by weight b) One or more pigments selected from the group consisting of rutile (titanium dioxide), zinc oxide, silicon oxide, zirconium oxide, and aluminum oxide, in the range of 3 to 6.5% by weight, said pigments being a mixture of nanometer-sized particles and micrometer-sized particles c) One or more coolants selected from L-menthyl glycerol ketal, DL-menthyl glycerol ketal, a mixture of these two, N-ethyl-p-menthane-3-carboxamide, menthol, isopulegol, monomethyl glutarate, 3-L-(menthyloxy)propane-1,2-diol, ethoxycarbonylmethyl-3-p-menthane carboxamide, essential oil of camphor, essential oil of mint, and essential oil of lavender, in the range of 0.5 to 4.5% by weight d) One or more radical scavengers selected from the extract of the root of Rhodiola sacra or Rhodiola rosea, the extract of the seed of Coix lacryma-jobi, the extract of the flower of Dendrobium nobile Lindl., the extract of Saururus involucratus, the extract of the flower of Calendula officinalis, the extract of the root of Paeonia lactiflora, the extract of the root of Scutellaria lateriflora, the extract of the root of Scutellaria baicalensis, the extract of the root of Salvia miltiorrhiza, the extract of the root of Bletilla striata, the extract of the leaf of Camellia sinensis, the extract of the bulb of Leucojum aestivum, the extract of the root of Astragalus membranaceus, the extract of the root of Saposhnikovia divaricata, the extract of the flower of Albizia julibrissin, the extract of the root of Gastrodia elata, the extract of Magnolia sieboldii, and tocopheryl acetate, in the range of 2 to 10% by weight e) Up to 100% by weight of a cosmetic carrier, excipient, and active substance Here, each weight percentage is a percentage relative to the total weight of the composition. **Claim 4** The composition according to any one of claims 1 to 3, which is a cosmetic sunscreen and sunscreen composition. **Claim 5** The composition according to any one of claims 1 to 4, which is an anti-aging composition. **Claim 6** The composition according to claim 1, comprising or consisting of a mixture of the substances described below: a) A UVA and UVB filter agent in the range of 14.5% by weight percentage b) One or more pigments selected from the group consisting of rutile (titanium dioxide), zinc oxide, silicon oxide, zirconium oxide, and aluminum oxide, in the range of 2 to 30% by weight percentage, said pigment being a mixture of nanometer-sized particles and micrometer-sized particles c) One or more coolants selected from L-menthyl glycerol ketal, DL-menthyl glycerol ketal, a mixture of these two, N-ethyl-p-menthane-3-carboxamide, menthol, isopulegol, monomethyl glutarate, 3-L-(menthyloxy)propane-1,2-diol, ethoxycarbonylmethyl-3-p-menthane carboxamide, essential oil of camphor, essential oil of mint, essential oil of lavender, in the range of 0.5 to 4.5% by weight percentage d) 1 to 5% by weight of an extract of the roots of Rhodiola rosea (Rhodiola sacra or Rhodiola rosea), an extract of the seeds of Coix lacryma-jobi, an extract of the flowers of Dendrobium nobile Lindl., an extract of Saururus involucratus, an extract of the flowers of Calendula officinalis, an extract of the roots of Paeonia lactiflora, an extract of the roots of Scutellaria lateriflora, an extract of the roots of Scutellaria baicalensis, an extract of the roots of Salvia multiolahiza, an extract of the roots of Bulbophyllum striatata, an extract of the leaves of green tea (Camellia sinensis), an extract of the bulbs of Leucojum aestivum, an extract of the roots of Astragalus membranaceus, an extract of the roots of Saposhnikovia divaricata, an extract of the flowers of Albizia julibrissin, an extract of the roots of Gastrodia elata, an extract of Magnolia sieboldii, and a radical scavenger selected from tocopheryl acetate e) Up to 100% by weight of a cosmetic carrier, excipient and active substance Here, each weight percentage is a percentage relative to the total weight of the composition.

7. [[ID= ​ ​ ​ d) Extracts of the roots of Rhodiola sakura or Rhodiola rosea, extracts of the seeds of Coix lacryma-jobi, extracts of the flowers of Dendrobium nobile Lindl., extracts of Saururus involucratus, extracts of the flowers of Calendula officinalis, extracts of the roots of Paeonia lactiflora, extracts of the roots of Scutellaria lateriflora, extracts of the roots of Scutellaria baicalensis, extracts of the roots of Salvia multiolaensis, extracts of the roots of Bretella striata, extracts of the leaves of Camellia sinensis, extracts of the bulbs of Leucojum aestivum, extracts of the roots of Astragalus membranaceus, extracts of the roots of Saposhnikovia divaricata, extracts of the flowers of Albizia julibrissin, extracts of the roots of Gastrodia elata, extracts of Magnolia sieboldii, and tocopheryl acetate, which are selected as radical scavengers, in an amount of 1 to 5% by weight e) Up to 100% by weight of a cosmetic carrier, excipient, and active substance Here, each weight percentage is a percentage based on the total weight of the composition

8. The pigment is a mixture of TiO and ZnO with different particle sizes, where 2 to 5 parts by weight of TiO with a particle size of 100 to 500 μm 2 and 1 to 2 parts by weight of ZnO are present, and further 12 to 24 parts by weight of TiO with a particle size of 10 to 600 nm 2 and 8 to 10 parts by weight of ZnO are present. The composition according to any one of claims 1 to 7 2 ​

9. The composition according to any one of claims 1 to 8, wherein the pigment is a mixture in which the weight ratio of nanometer-sized particles to micrometer-sized particles is 5:1 to 8:1

10. The composition according to claim 8 or 9, wherein the small particle size ranges from 10 to 300 nm and the large particle size ranges from 100 to 250 μm

11. The pigment is a mixture of TiO with a size of 10 to 600 nm 2 and TiO with a size of 100 to 500 μm 2 The composition according to any one of claims 1 to 7, wherein the weight ratio of the nanoparticles to the microparticles is 5:1 to 10:

1.

12. The composition according to any one of claims 1 to 11, wherein the radical scavenger has a radical defense index of 40 to 100,000, either alone or as a mixture

13. The composition according to any one of claims 1 to 12, wherein the radical scavenger has a radical defense index of 40 to 40,000, either alone or as a mixture

14. The composition according to any one of claims 1 to 13, wherein the radical scavenger has a radical defense index of 500 to 100,000, either alone or as a mixture

15. The composition according to any one of claims 1 to 14, having a radical defense index of 20 to 4,000.

16. The composition according to any one of claims 1 to 15, having a sun protection index exceeding 40.

17. The composition according to any one of claims 1 to 16, wherein the radical scavenger is a hydrophilic compound.

18. The UVA and UVB filter agents are selected from bisethylhexyl oxy phenol methoxyphenyl triazine, droxmetrizole trisiloxane, terephthalylidene dicamphor sulfonic acid, ethylhexyl triazone, butyl methoxydibenzoylmethane, diethylamino hydroxybenzoyl hexyl benzoate, diethylhexyl butamido triazone, phenyl benzimidazole sulfonic acid, ethylhexyl methoxycinnamate, ethylhexyl salicylate, methylene bisbenzotriazolyl tetramethylbutyl phenol, octocrylene and phenyl benzimidazole sulfonic acid, or a mixture consisting of two or more of these listed components. The composition according to any one of claims 1 to 17.

19. The composition according to any one of claims 1 to 18, wherein the coolant is menthol.

20. The composition according to any one of claims 1 to 19, which is in the form of milk, gel, lotion, stick, water-in-oil emulsion, oil-in-water emulsion, or fluid emulsion.

21. Use of a mixture of the substances described below as a sunscreen and sunscreen composition for protecting the skin of humans with Fitzpatrick skin types IV and V derived from the Fitzpatrick scale: a) UVA and UVB filter agents in the range of 5 to 24% by weight b) One or more pigments selected from the group consisting of rutile (titanium dioxide), zinc oxide, silicon oxide, zirconium oxide, and aluminum oxide in the range of 2 to 30% by weight, said pigments being a mixture of nanoparticles and microparticles c) One or more cooling agents selected from L-menthyl glycerol ketal, DL-menthyl glycerol ketal, a mixture of these two, N-ethyl-p-menthane-3-carboxamide, menthol, isopulegol, monomethyl glutarate, 3-L-(menthyloxy)propane-1,2-diol, ethoxycarbonylmethyl-3-p-menthane carboxamide, essential oil of camphor, essential oil of mint, essential oil of lavender, in an amount of 0.5 to 4.5% by weight d) One or more radical scavengers selected from extract of roots of Rhodiola sakura or Rhodiola rosea, extract of seeds of Coix lacryma-jobi, extract of flowers of Dendrobium nobile Lindl, extract of Saururus involucratus, extract of flowers of Calendula officinalis, extract of roots of Paeonia lactiflora, extract of roots of Scutellaria lateriflora, extract of roots of Scutellaria baicalensis, extract of roots of Salvia miltiorrhiza, extract of roots of Bretillia striata, extract of leaves of green tea (Camellia sinensis), extract of bulbs of Leucojum aestivum, extract of roots of Astragalus membranaceus, extract of roots of Saposhnikovia divaricata, extract of flowers of Albizia julibrissin, extract of roots of Gastrodia elata, extract of Magnolia sieboldii, and tocopheryl acetate, in an amount of 1 to 10% by weight e) Up to 100% by weight of a cosmetic carrier, excipient and active substance Here, each percentage by weight is based on the total weight of the composition

22. Use as a sunscreen and sunscreen composition according to claim 21 a) A UVA and UVB filter agent in the range of 5 to 24% by weight b) One or more pigments selected from the group consisting of rutile (titanium dioxide), zinc oxide, silicon oxide, zirconium oxide, aluminum oxide, in an amount of 2 to 30% by weight, said pigment being a mixture of nanoparticles and microparticles c) One or more cooling agents selected from L-menthone glycerol ketal, DL-menthone glycerol ketal, a mixture of these two, N-ethyl-p-menthane-3-carboxamide, menthol, isopulegol, monomethyl glutarate, 3-L-(menthyloxy)propane-1,2-diol, ethoxycarbonylmethyl-3-p-menthane carboxamide, essential oil of camphor, essential oil of mint, essential oil of lavender, in an amount of 0.5 to 4.5% by weight d) One or more radical scavengers selected from extract of roots of Rhodiola sakura or Rhodiola rosea, extract of seeds of Coix lacryma-jobi, extract of flowers of Dendrobium nobile Lindl, extract of Saururus involucratus, extract of flowers of Calendula officinalis, extract of roots of Paeonia lactiflora, extract of roots of Scutellaria lateriflora, extract of roots of Scutellaria baicalensis, extract of roots of Salvia miltiorrhiza, extract of roots of Bretillia striata, extract of leaves of green tea (Camellia sinensis), extract of bulbs of Leucojum aestivum, extract of roots of Astragalus membranaceus, extract of roots of Saposhnikovia divaricata, extract of flowers of Albizia julibrissin, extract of roots of Gastrodia elata, extract of Magnolia sieboldii, and tocopheryl acetate, in an amount of 1 to 5% by weight e) Up to 100% by weight of a cosmetic carrier, excipient and active substance Here, each weight percentage is a percentage relative to the total weight of the composition.

23. Use of the mixture of substances described below as a sunscreen and sunblock composition according to Claim 21 a) A UVA and UVB filter agent in the range of 5 to 24% by weight b) One or more pigments selected from the group consisting of rutile (titanium dioxide), zinc oxide, silicon oxide, zirconium oxide, aluminum oxide, in an amount of 3 to 6.5% by weight, said pigment being a mixture of nanometer-sized particles and micrometer-sized particles c) One or more cooling agents selected from L-menthone glycerol ketal, DL-menthone glycerol ketal, a mixture of these two, N-ethyl-p-menthane-3-carboxamide, menthol, isopulegol, monomethyl glutarate, 3-L-(menthyloxy)propane-1,2-diol, ethoxycarbonylmethyl-3-p-menthane carboxamide, essential oil of camphor, essential oil of mint, and essential oil of lavender, in an amount of 0.5 to 4.5% by weight. d) One or more radical scavengers selected from extracts of the roots of Rhodiola sakura or Rhodiola rosea, extracts of the seeds of Coix lacryma-jobi, extracts of the flowers of Dendrobium nobile Lindl., extracts of Saururus involucratus, extracts of the flowers of Calendula officinalis, extracts of the roots of Paeonia lactiflora, extracts of the roots of Scutellaria lateriflora, extracts of the roots of Scutellaria baicalensis, extracts of the roots of Salvia miltiorrhiza, extracts of the roots of Bletilla striata, extracts of the leaves of Camellia sinensis, extracts of the bulbs of Leucojum aestivum, extracts of the roots of Astragalus membranaceus, extracts of the roots of Saposhnikovia divaricata, extracts of the flowers of Albizia julibrissin, extracts of the roots of Gastrodia elata, extracts of Magnolia sieboldii, and tocopheryl acetate, in an amount of 2 to 10% by weight. e) Up to 100% by weight of a cosmetic carrier, excipient, and active substance. Here, each percentage by weight is a percentage based on the total weight of the composition.

24. Use of a mixture of the substances described below as an anti-aging composition for protecting the skin of humans with Fitzpatrick skin types IV and V derived from the Fitzpatrick scale. a) UVA and UVB filter agents in the range of 5 to 24% by weight. b) 2 to 30% by weight of one or more pigments selected from the group consisting of rutile (titanium dioxide), zinc oxide, silicon oxide, zirconium oxide, and aluminum oxide, said pigments being a mixture of nanometer-sized particles and micrometer-sized particles c) 0.5 to 4.5% by weight of one or more cooling agents selected from L-menthone glycerol ketal, DL-menthone glycerol ketal, mixtures of these two, N-ethyl-p-menthane-3-carboxamide, menthol, isopulegol, monomethyl glutarate, 3-L-(menthyloxy)propane-1,2-diol, ethoxycarbonylmethyl-3-p-menthane carboxamide, essential oil of camphor, essential oil of mint, and essential oil of lavender d) 1 to 10% by weight of a radical scavenger selected from the extract of the root of Rhodiola sakura or Rhodiola rosea, the extract of the seed of Coix lacryma-jobi, the extract of the flower of Dendrobium nobile Lindl, the extract of Saururus involucratus, the extract of the flower of Calendula officinalis, the extract of the root of Paeonia lactiflora, the extract of the root of Scutellaria lateriflora, the extract of the root of Scutellaria baicalensis, the extract of the root of Salvia miltiorrhiza, the extract of the root of Bretella striata, the extract of the leaf of Camellia sinensis, the extract of the bulb of Leucojum aestivum, the extract of the root of Astragalus membranaceus, the extract of the root of Saposhnikovia divaricata, the extract of the flower of Albizia julibrissin, the extract of the root of Gastrodia elata, the extract of Magnolia sieboldii, and tocopheryl acetate e) Up to 100% by weight of a cosmetic carrier, excipient, and active substance Here, each weight percentage is a percentage based on the total weight of the composition.

25. Use of the mixture of substances described below as the anti-aging composition according to claim 24: a) A UVA and UVB filter agent in the range of 5 to 24% by weight b) 2 to 30% by weight of one or more pigments selected from the group consisting of rutile (titanium dioxide), zinc oxide, silicon oxide, zirconium oxide, and aluminum oxide, said pigments being a mixture of nanometer-sized particles and micrometer-sized particles c) 0.5 to 4.5% by weight of one or more coolants selected from L-menthone glycerol ketal, DL-menthone glycerol ketal, a mixture of these two, N-ethyl-p-menthane-3-carboxamide, menthol, isopulegol, monomethyl glutarate, 3-L-(menthyloxy)propane-1,2-diol, ethoxycarbonylmethyl-3-p-menthane carboxamide, essential oil of camphor, essential oil of mint, and essential oil of lavender d) 1 to 5% by weight of a radical scavenger selected from the extract of the root of Rhodiola sakura or Rhodiola rosea, the extract of the seed of Coix lacryma-jobi, the extract of the flower of Dendrobium nobile Lindl, the extract of Saururus involucratus, the extract of the flower of Calendula officinalis, the extract of the root of Paeonia lactiflora, the extract of the root of Scutellaria lateriflora, the extract of the root of Scutellaria baicalensis, the extract of the root of Salvia miltiorrhiza, the extract of the root of Bletilla striata, the extract of the leaf of Camellia sinensis, the extract of the bulb of Leucojum aestivum, the extract of the root of Astragalus membranaceus, the extract of the root of Saposhnikovia divaricata, the extract of the flower of Albizia julibrissin, the extract of the root of Gastrodia elata, the extract of Magnolia sieboldii, and tocopheryl acetate e) Up to 100% by weight of a cosmetic carrier, excipient, and active substance Here, each weight percentage is a percentage relative to the total weight of the composition.

26. Use of the mixture of substances described below as the anti-aging composition according to Claim 25: a) A UVA and UVB filter agent in the range of 5 to 24% by weight b) One or more pigments selected from the group consisting of rutile (titanium dioxide), zinc oxide, silicon oxide, zirconium oxide, and aluminum oxide, in an amount of 3 to 6.5% by weight, said pigments being a mixture of nanometer-sized particles and micrometer-sized particles c) One or more coolants selected from L-menthone glycerol ketal, DL-menthone glycerol ketal, a mixture of these two, N-ethyl-p-menthane-3-carboxamide, menthol, isopulegol, monomethyl glutarate, 3-L-(menthyloxy)propane-1,2-diol, ethoxycarbonylmethyl-3-p-menthane carboxamide, essential oil of camphor, essential oil of mint, and essential oil of lavender, in an amount of 0.5 to 4.5% by weight d) One or more radical scavengers selected from the extract of the root of Rhodiola sakura or Rhodiola rosea, the extract of the seed of Coix lacryma-jobi, the extract of the flower of Dendrobium nobile Lindl., the extract of Saururus involucratus, the extract of the flower of Calendula officinalis, the extract of the root of Paeonia lactiflora, the extract of the root of Scutellaria lateriflora, the extract of the root of Scutellaria baicalensis, the extract of the root of Salvia miltiorrhiza, the extract of the root of Bletilla striata, the extract of the leaf of Camellia sinensis, the extract of the bulb of Leucojum aestivum, the extract of the root of Astragalus membranaceus, the extract of the root of Saposhnikovia divaricata, the extract of the flower of Albizia julibrissin, the extract of the root of Gastrodia elata, the extract of Magnolia sieboldii, and tocopheryl acetate, in an amount of 2 to 10% by weight e) Up to 100% by weight of a cosmetic carrier, excipient, and active substance Here, each weight percentage is a percentage based on the total weight of the composition

27. The pigment is a mixture of TiO and ZnO with different particle sizes, where there are 2 - 5 parts by weight of TiO with a particle size of 100 - 500 μm 2 and 1 - 2 parts by weight of ZnO, and further there are 12 - 24 parts by weight of TiO with a particle size of 10 - 600 nm 2 and 8 - 10 parts by weight of ZnO, the use according to any one of claims 22 - 26 2 wherein the above components exist.

28. Use of the composition according to any one of claims 22 to 27, wherein the UVA and UVB filter agent is selected from bisethylhexyloxyphenol methoxyphenyltriazine, droxmetrizole trisiloxane, terephthalylidene dicamphor sulfonic acid, ethylhexyl triazone, butyl methoxydibenzoylmethane, diethylamino hydroxybenzoyl hexyl benzoate, diethylhexyl butamido triazone, phenylbenzimidazole sulfonic acid, ethylhexyl methoxycinnamate, ethylhexyl salicylate, methylene bisbenzotriazolyl tetramethylbutylphenol, octocrylene and phenylbenzimidazole sulfonic acid, or is a mixture comprising two or more of these listed components.

29. Use of the composition according to any one of claims 22 to 28, wherein the pigment is a mixture of titanium dioxide and zinc oxide.

30. Use of the composition according to any one of claims 22 to 26, wherein the coolant is menthol.

31. The composition according to any one of claims 1 to 20 for use in protecting against damage caused by free radicals in humans.

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