Fragrances or aroma compositions that are acceptable or preferred by pets
Fragrance and aroma compositions with gourmand and musk impressions are developed to address pet aversion issues, attracting pets and enhancing pet-owner bonding by being both pet and human-friendly.
Patent Information
- Application Number
- JP2024506929
- Authority / Receiving Office
- JP · JP
- Patent Type
- Patents
- Current Assignee / Owner
- Priority Date
- 2021-08-06
- Filing Date
- 2021-12-21
- Publication Date
- 2025-08-15
- Estimated Expiration
- 2041-12-21
AI Technical Summary
Existing consumer products are designed primarily for human fragrance preferences, leading to negative behavioral responses in pets, particularly cats, such as litter box aversion and inappropriate elimination, due to unpleasant scents.
Development of fragrance and aroma compositions with gourmand and musk odor impressions that are well-accepted by both cats and dogs, while avoiding woody odor impressions that are unpleasant to them.
The compositions effectively attract pets to desired areas, such as litter boxes, and are pleasant to both pets and humans, addressing litter box aversion and improving pet-owner bonding.
Smart Images

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Abstract
Description
[Technical Field]
[0001] The present invention relates to novel fragrance or aroma / flavor compositions that are acceptable or preferred by pets, in particular pet fragrance or pet aroma / flavor compositions. The present invention also relates to the use of such fragrance or aroma / flavor compositions for preparing scented or flavored products that are acceptable or preferred by pets, in particular scented or flavored pet products. Furthermore, the present invention relates to scented or flavored products comprising the fragrance or aroma / flavor compositions. Finally, the present invention relates to a method for scenting a pet, product, or room by applying a fragrance composition or scented product. [Background technology]
[0002] With the improvement of people's living standards and the accelerating urbanization of society, pets have increasingly become part of the family and are therefore routinely exposed to consumer fragrances. Product odor acceptance is a major driver of overall product acceptance. To date, most home care products have been designed with consumer acceptance in mind. Products are extensively tested and optimized for fragrances and properties most pleasing to humans. However, until now, little attention has been paid to fragrances and products that pets themselves accept. Humans have 15 million olfactory neurons, cats 67 million, and dogs 200 million. Although our pets' ability to smell varies, we do not understand how they respond to fragrances in typical consumer products.
[0003] When cats find scents in litter that they find unpleasant, it can lead to negative elimination behaviors, such as refusal to use the litter box or complete refusal, often manifested by depositing unwanted feces elsewhere in the home. Inappropriate elimination is the most common behavioral problem reported by cat owners and often damages the bond between pet and owner. The primary cause of this negative behavior is litter box aversion, caused by litter that cats find unpleasant.
[0004] WO2016 / 170475A1 discloses the use of L-Feline (2-amino-7-hydroxy-5,5-dimethyl-4-thiaheptanoic acid) to attract cats to defecate in a litter box. According to the disclosure, 21 commercially available cat attractants containing L-Feline were tested and evaluated for their preference for cats to defecate in the litter box compared to a control. Only L-Feline was significantly preferred by cats for urinating.
[0005] WO2019 / 1455574A1 relates to cat litter containing a composition comprising 2,2-dimethyl-1,3-dioxalane-4-methanol.
[0006] Therefore, there is a continuing interest within the fragrance or aroma / flavor industry in developing new fragrances or aromas that are attractive to pets, particularly cats and dogs. There is a further need for consumer products to be accepted by pets who share the same environment as their owners in the home, as the safety and health of pets largely depend on it.
[0007] It is therefore an object of the present invention to provide a fragrance or aroma / flavor composition, in particular a fragrance or aroma / flavor composition for pets, that is accepted and not rejected by pets. Another object of the present invention is to provide a consumer product or pet product that is organoleptic, i.e., that is organoleptic by virtue of an odor or taste that is acceptable to pets.
[0008] The present invention demonstrates that certain fragrances or aroma / flavor compositions are accepted and not rejected by pets.
[0009] The present invention is based on the surprising finding that fragrance trends, preferably having at least one compound or lead sensory component with a gourmand odor-type impression, or preferably having at least one compound or lead sensory component with a musky odor-type impression, are well accepted by both cats and dogs, whereas fragrance trends, preferably having at least one compound or lead sensory component with a woody odor-type impression, are unpleasant and therefore poorly accepted by both cats and dogs. Summary of the Invention
[0010] In a first aspect, the invention comprises a compound, preferably having a gourmand odor impression, wherein the compound is Vanillin (4-hydroxy-3-methoxybenzaldehyde), Ethyl vanillin (3-ethoxy-4-hydroxybenzaldehyde), Ethyl maltol (2-ethyl-3-hydroxy-4H-pyran-4-one), Coumarin (2H-1-benzopyran-2-one), Tonkalactone® (3,6-dimethyl-3H-l-benzofuran-2-one), Frambinone® (4-(p-methoxyphenyl)-2-butanone), benzaldehyde, ethyl-2-methyl butyrate, 2-methoxy-3-ethylpyrazine, Delta-decalactone, delta-nonalactone, gamma-octalactone, and mixtures thereof; and / or Preferably, the compound has a musk odor impression, Aldrone (4-[(6,6-dimethyl-5-bicyclo[2.2.1]heptanyl)methyl]-2-methylcyclohexan-1-one), Lactoskane ((2R,4aR,8aS)-2,8,8-trimethyloctahydro-2H-4a,2-(epoxymethano)naphthalen-10-one), Ambrettolide (17-oxacycloheptadec-6-en-1-one), Ethylene brassylate (1,4-dioxacycloheptadecane-5,17-dione), Globalide® ((3E)-oxacyclohexadec-3-en-2-one), Globanone ((8E)-cyclohexadec-8-en-1-one), and mixtures thereof.
[0011] In a second aspect, the present invention relates to the use of a fragrance composition or aroma / flavor composition, in particular a pet fragrance composition or pet aroma / flavor composition, for preparing a scented or flavored product, preferably a scented or flavored pet product.
[0012] In a third aspect, the present invention relates to a scented product, such as a personal or home care product, a surface care product, a cleaning product, an air care product, a textile product, an auto care product, a pet care product, or a flavored product, such as a pet treat, breath, and oral care product, or an edible pet product, comprising an effective amount of a fragrance or aroma / flavor composition according to the present invention.
[0013] In a final aspect, the present invention provides a method for producing a medicament for the treatment of a pulmonary arthritis, comprising: (i) providing a fragrance composition according to the invention or a scented product according to the invention; (ii) applying a sensory effective amount of the fragrance composition or scented product to the pet, product, or room to produce an odor acceptable to the pet.
[0014] Further aspects of the present invention will emerge from the following description, examples and appended patent claims. [Brief explanation of the drawings]
[0015] [Figure 1] FIG. 10 shows exemplary average deposit weight per condition for rejected fragrance (Jasmine Accord). [Figure 2] FIG. 1 shows exemplary average deposit weight per condition for the received fragrance (musk accord). [Figure 3] 1 is a histogram showing the significance of weight results in cat litter comparing Jasmine Accord to Musk Accord. [Figure 4] FIG. 1 shows the rejection ratio for vanillin and jasmine accords in a canine evaluation. [Figure 5] FIG. 1 shows a summary of cat hedonic outcomes summarizing accepted and unaccepted scents / accords. [Figure 6] FIG. 1 shows a summary of dog hedonicity results summarizing accepted scents / accords. DETAILED DESCRIPTION OF THE INVENTION
[0016] Within the context of the present invention, a fragrance composition is generally a composition that comprises an individual compound or two or more different classes of compounds to impart an odor or smell.
[0017] Within the context of the present invention, an aroma / flavor composition is generally a composition that contains an individual compound or two or more different classes of compounds to impart a flavor or taste sensation.
[0018] Flavor affects both the sense of taste and smell, whereas aroma affects only smell.
[0019] The compositions according to the invention can be either fragrance compositions or aroma / flavor compositions.
[0020] Therefore, in the context of the present invention, the terms "aroma" and "flavor" are used interchangeably and with the same meaning.
[0021] Whenever in the description a fragrance composition or an aroma / flavor composition according to the invention is mentioned, this is taken to also refer to a pet fragrance composition or a pet aroma / flavor composition according to the invention.
[0022] Within the context of the present invention, the term "effective amount" refers to the amount of at least one compound or key sensory component necessary or sufficient to produce a desired response in a pet, i.e., the amount that imparts a perceptible odor or flavor to the fragrance or aroma / flavor composition incorporated therein, or to the final product. When applied to a flavorant or fragrance combination, the term refers to the total amount of flavorant or fragrance combination that produces the odor or flavor. Most importantly, the user must be able to perceive the odor or taste upon administering the fragrance or flavor composition according to its typical usage instructions.
[0023] The term "comprising" means that the named component is essential, but that other components may be added and are also encompassed by the present invention.
[0024] As used in accordance with the present invention, the term "consisting of" means that the total amount of ingredients adds up to 100% by weight based on the total weight of the composition, and indicates that the subject matter is closed-ended and includes only those limitations expressly recited.
[0025] Whenever "comprising" is mentioned, both meanings are intended to be covered as alternatives, i.e., the meaning can be either "comprising" or "consisting of," unless the context dictates otherwise.
[0026] The term "at least one compound or primary sensory ingredient" means that the compositions of the present invention can contain either one ingredient or primary sensory ingredient, or a mixture of two, three, or even more different compounds or primary sensory ingredients.
[0027] The term "compound" or "major sensory component" in the context of the present invention refers to a compound or component that has a particular sensory effect, such as a gourmand, musky, or woody note, that is a major component in the fragrance or aroma / flavor composition according to the present invention, and that has the most significant influence on the olfactory or gustatory effect of the fragrance or aroma / flavor composition. For example, if the major sensory component is a compound that preferably has gourmand-type notes, the resulting composition will have a predominantly gourmand-type impression. If the major sensory component is a compound that preferably has musky-type notes, the resulting composition will have a predominantly musky-type impression, etc.
[0028] The term "optionally" means that the subsequently described compound may, but need not, be present in the composition, and that the description includes variations in which the compound is included or in which the compound is not present.
[0029] According to the invention, the above object consists of a compound that preferably has a gourmand odor impression, said compound being Vanillin (4-hydroxy-3-methoxybenzaldehyde), Ethyl vanillin (3-ethoxy-4-hydroxybenzaldehyde), Ethyl maltol (2-ethyl-3-hydroxy-4H-pyran-4-one), Coumarin (2H-1-benzopyran-2-one), Tonkalactone® (3,6-dimethyl-3H-l-benzofuran-2-one), Frambinon® (4-(p-methoxyphenyl)-2-butanone), benzaldehyde, ethyl-2-methyl butyrate, 2-methoxy-3-ethylpyrazine, Delta-decalactone, delta-nonalactone, gamma-octalactone, and a mixture of two, three or more of the above-mentioned compounds.
[0030] In a preferred variant, the fragrance composition or aroma / flavor composition according to the invention comprises Vanillin (4-hydroxy-3-methoxybenzaldehyde), Comprising or consisting of a compound or primary sensory ingredient of Group (A) selected from the group consisting of Tonkalactone® (3,6-dimethyl-3H-l-benzofuran-2-one), and a mixture of two of the above compounds.
[0031] In a preferred variant, the fragrance composition or aroma / flavor composition according to the invention comprises vanillin and Tonkalactone®.
[0032] Preferably, compounds with a gourmand odor impression are characterized by an edible odor / odor or flavor / taste, including but not limited to vanilla, sugar candy, whipped or caramelized sugar, honey, chocolate, caramel, almond, coconut, creamy, minty, cinnamon and / or nutty odor / odor or flavor / taste impressions.
[0033] The compounds or primary sensory ingredients identified above can be used as individual substances or in mixtures with at least one other (in the context designated below as Accords).
[0034] In a preferred variant according to the invention, the fragrance or aroma / flavor composition according to the invention therefore comprises a sensory effective amount of at least one or more, i.e. a mixture of two, three or more, compounds or primary sensory components of group (A), preferably consisting of compounds with gourmand-type odor notes.
[0035] Preferred fragrance / accord compositions with gourmand-type odor notes according to the present invention are those which comprise one, two, three or more compound(s) or key sensory component(s) of group (A), for example as identified in Table 1 below.
[0036] [Table 1]
[0037] As can be seen from the exemplary compositions in Table 1, the fragrance or aroma / flavor composition may comprise a single compound or primary sensory component as defined above, or the fragrance or aroma / flavor composition may be an accord of two or more different compounds or primary sensory components as defined above.
[0038] Alternatively, the above object preferably consists of a compound having a musk odor impression, Aldrone (4-[(6,6-dimethyl-5-bicyclo[2.2.1]heptanyl)methyl]-2-methylcyclohexan-1-one), Lactoskane ((2R,4aR,8aS)-2,8,8-trimethyloctahydro-2H-4a,2-(epoxymethano)naphthalen-10-one), Ambrettolide (17-oxacycloheptadec-6-en-1-one), Ethylene brassylate (1,4-dioxacycloheptadecane-5,17-dione), Globalide® ((3E)-oxacyclohexadec-3-en-2-one), Globanone ((8E)-cyclohexadec-8-en-1-one), and a mixture of two, three or more of the above-mentioned compounds.
[0039] In a preferred variant, the fragrance or aroma / flavor composition according to the invention comprises: Ambrettolide (17-oxacycloheptadec-6-en-1-one), Globalide® ((3E)-oxacyclohexadec-3-en-2-one), Globanone ((8E)-cyclohexadec-8-en-1-one) and (B) a compound or primary sensory ingredient selected from the group consisting of a mixture of two or three of the above compounds.
[0040] Particularly preferred are: Ambretride and Globalide®, or Ambrette and Grobanon, or Globalide® and Globanon, or A mixture / combination of compounds or key sensory ingredients selected from the group consisting of ambrettolide, Globalide® and Globanone.
[0041] Preferably, compounds with a musk-type odor impression are characterized by a musky odor / smell, most typically described as animalic, but also with odor / smell or flavor / taste impressions ranging from sweet, creamy, or powdery to rich, leathery, spicy.
[0042] The compounds or primary sensory ingredients identified above can be used as individual substances or in mixtures with at least one other (in the context designated below as Accords).
[0043] In a preferred variant according to the invention, the fragrance or aroma / flavor composition according to the invention therefore comprises a sensory effective amount of at least one or more, i.e. a mixture of two, three or more, of compounds or primary sensory components of group (B), preferably consisting of compounds with an odor note of the musky odor type.
[0044] Preferred fragrance / accord compositions with musky-type odor notes according to the present invention are those which comprise one, two, three or more compound(s) or key sensory component(s) of group (B) as identified in Table 2 below, for example.
[0045] [Table 2]
[0046] As can be seen from the exemplary compositions in Table 2, the fragrance or aroma / flavor composition may comprise a single compound or primary sensory component as defined above, or the fragrance or aroma / flavor composition may be an accord of two or more different compounds or primary sensory components as defined above.
[0047] In a further variant, the fragrance or aroma / flavor composition, preferably a pet fragrance or pet aroma / flavor composition, according to the invention comprises a sensory effective amount of at least one compound or major sensory component from group (A) as specified above, preferably consisting of compounds with a gourmand odor-type impression, and at least one compound or major sensory component from group (B), as specified above, preferably consisting of compounds with a musky odor-type impression.
[0048] In a preferred variant according to the invention, the fragrance or aroma / flavor composition according to the invention comprises a mixture of two, three or more compounds or main sensory components of group (A), preferably consisting of compounds with gourmand-type odor notes, and two, three or more compounds or main sensory components of group (B), preferably consisting of compounds with musky-type odor notes.
[0049] In a further preferred variant, the fragrance or aroma / flavor composition according to the invention comprises: Tonkalactone® (3,6-dimethyl-3H-l-benzofuran-2-one), Vanillin (4-hydroxy-3-methoxybenzaldehyde), Globalide® ((3E)-oxacyclohexadec-3-en-2-one), Ethylene brassylate (1,4-dioxacycloheptadecane-5,17-dione) and a mixture of two or more of the foregoing compounds, comprising or consisting of a compound or primary sensory ingredient selected from the group consisting of:
[0050] Particularly preferred are: Tonkalactone® and vanillin; or Tonkalactone® and Globalide®; or Tonkalactone® and ethylene brassylate; or Vanillin and Globalide®; or Vanillin and ethylene brassylate; or Globalide® and ethylene brassylate; or Tonkalactone® with vanillin and Globalide®; or Tonkalactone®, vanillin, and ethylene brassylate; or A mixture of compounds or primary sensory ingredients selected from the group consisting of Vanillin, Globalide® and ethylene brassylate.
[0051] Surprisingly, as demonstrated by the experimental data in the following examples by measuring behavioral parameters, the above-identified fragrance or aroma / flavor trends have been found to be attractive to both cats and dogs, while also being pleasant to humans. Thus, it has been unexpectedly observed that the fragrance or aroma / flavor compositions according to the present invention are able to advantageously attract pets, preferably cats or dogs.
[0052] Similarly, the tendency of certain fragrances or aromas / flavors to have a woody odor type impression is an unpleasant fragrance that is rejected by both cats and dogs, as demonstrated by the experimental data in the Examples below by measuring behavioral parameters.
[0053] In a further and particularly preferred variant, the present invention therefore relates to a fragrance or aroma / flavor composition, preferably a fragrance or aroma / flavor composition for pets, which does not contain at least one compound or major sensory component of group (C), preferably consisting of compounds with a woody odor impression, such unpleasant substances being selected from the group consisting of cedarwood oil, blond wood, bleach accord, jasmine accord, orange flower and mixtures thereof.
[0054] Therefore, in a preferred variant, the fragrance or aroma / flavor composition according to the invention, preferably a fragrance or aroma / flavor composition for pets, does not comprise any of the compounds or primary sensory components of group (C) as defined previously.
[0055] Fragrance / accord compositions with a woody odor type impression according to the present invention are, for example, those identified in Table 3 below.
[0056] [Table 3]
[0057] In the fragrance or aroma / flavor composition according to the first aspect of the present invention, the amount of at least one compound or major sensory component from group A and / or at least one compound or major sensory component from group B used is preferably in the range of 1 to 100% by weight, preferably in the range of 5 to 90% by weight, more preferably in the range of 10 to 80% by weight, even more preferably in the range of 20 to 70% by weight, particularly preferably in the range of 30 to 60% by weight, and most preferably in the range of 40 to 50% by weight, relative to the total weight of the composition. If the fragrance or aroma / flavor composition comprises a blend of said compounds or major sensory components, the weight specifications above relate to the blend.
[0058] In yet a further and preferred variant, the fragrance or aroma / flavor composition, preferably the pet fragrance composition or pet aroma / flavor composition, according to the first aspect of the invention further comprises one or more additional fragrance substances, preferably with a floral odor-type impression, selected from the group consisting of methyloctyne carbonate (methyl-non-2-ynoate), phenylethyl alcohol (2-phenylethan-1-ol), citronellol (3,7-dimethyloct-6-en-1-ol), lavender oil, peppermint oil, and mixtures of two or more of the aforementioned compounds.
[0059] Lavender essential oil is produced via steam distillation. The exact composition of lavender essential oil varies from species to species, but it is composed primarily of monoterpenoid and sesquiterpenoid components. Among these, or major sensory components, linalool and linalyl acetate predominate, with lavandulyl acetate, terpinen-4-ol, and lavandulol present at moderate levels, and 1,3-cineole and camphor present in small to moderate amounts. Peppermint oil is composed primarily of menthol and menthone as the major sensory components, as well as several minor components, including menthofuran, 1,8-cineole, and limonene.
[0060] In yet a further and preferred variant, the fragrance or aroma / flavor composition, preferably a pet fragrance composition or a pet aroma / flavor composition, according to the first aspect of the present invention further comprises one or more additional fragrance substances, preferably with a citrus-type odor impression, such additional fragrance substances, preferably with a citrus-type odor impression, selected from the group consisting of orange oil, lily of the valley oil, mandarin aldehyde (trans-2-dodecenal), agglunitrile (3,7-dimethyloct-6-enenitrile), citral (3,7-dimethyl-2,6-octadienal), and mixtures of two or more of the aforementioned compounds.
[0061] The present invention is dedicated to pets. Preferably, pets are mammals. In the context of the present invention, dogs and cats are preferred.
[0062] The fragrance or aroma / flavour composition according to the first aspect of the present invention, preferably the pet fragrance composition or pet aroma / flavour composition, is characterised by high acceptability by pets, preferably by cats and / or dogs.
[0063] The fragrance or aroma / flavor composition according to the present invention may be used for scenting or flavoring. The fragrance or aroma / flavor composition as defined herein may be used as such or alternatively in liquid form, i.e. in solution, either undiluted or diluted with a solvent.
[0064] Suitable solvents for this purpose are, for example, ethanol, isopropanol, diethylene glycol monoethyl ether, glycerol, propylene glycol, 1,2-butylene glycol, dipropylene glycol, diethyl phthalate, triethyl citrate, isopropyl myristate, triacetin, vegetable oils, 2,2,4-trimethyl-1,3-pentanediol monoisobutyrate, tripropylene glycol methyl ether, dipropylene glycol monomethyl ether, dioctyl adipate, 2,2-dimethyl-1,3-dioxolane-4-methanol, diisopropanolamine, silicones, isopropyl palmitate, isostearyl alcohol, and / or methyl hydrogenated resinate.
[0065] Furthermore, the fragrance or aroma / flavor compositions according to the invention may be absorbed in a carrier that ensures both a fine distribution of the aroma / flavor or fragrance substance in the product and a controlled release during use. Such a carrier may be, for example, a porous inorganic material such as sodium sulfate, silica, zeolite, gypsum, clay, clay granules, aerated concrete, etc., or an organic material such as wood, cellulosic materials, sugars, dextrins (e.g., maltodextrin), or a plastic such as PVC, polyvinyl acetate, polyurethanes, acrylates, synthetic fibers.
[0066] The fragrance or aroma / flavor composition according to the present invention may be spray dried, may be provided as an inclusion complex or as an extruded product or in microencapsulated form.
[0067] Spray-dried aroma or flavor compositions may be prepared by spray-drying an emulsion or dispersion containing the flavor or aroma composition, where modified starches, proteins, dextrins and vegetable gums may be used as carriers. Inclusion complexes may be prepared, for example, by introducing a dispersion of the flavor or aroma substance composition and a cyclodextrin or urea derivative into a suitable solvent, for example water.
[0068] The extruded product may be produced by melting the aroma or flavor composition together with a suitable waxy material, optionally extruding with a suitable solvent, for example isopropanol, and then solidifying.
[0069] Optionally, the properties of the composition thus modified may be further optimized for more targeted flavor or aroma release by "coating" it with a suitable material; for this purpose, waxy plastics such as polyvinyl alcohol are preferably used.
[0070] The flavor or fragrance compositions according to the present invention may be encapsulated by coacervation techniques with the aid of encapsulants made of, for example, polyurethane-type materials or soft gelatin.
[0071] All of the above obtained product variants are fragrance or aroma / flavor compositions according to the present invention.
[0072] Due to their inherent beneficial taste and / or olfactory properties accepted by pets, the fragrance or flavor compositions according to the present invention, preferably pet fragrance or pet flavor compositions, are advantageous for preparing scented or flavored products, preferably scented or flavored pet products.
[0073] Another aspect of the present invention therefore relates to the use of a fragrance or aroma / flavor composition as described above for preparing a scented or flavored product, preferably a scented or flavored pet product. With regard to the preferred variants of the fragrance or aroma / flavor composition according to the invention, the above statements naturally apply analogously.
[0074] The fragrance compositions according to the present invention may be incorporated into products that are flavored or scented or intended to be flavored or scented, preferably personal or home care products, surface care products, cleaning products, air care products, textile products, auto care products, pet care grooming products, or oral care products, or edible pet products.
[0075] According to a preferred development, the scented or flavored product containing the fragrance composition or aroma / flavor composition according to the invention is produced by incorporating the fragrance composition or aroma / flavor composition solvent-free, in solution or in the form of a mixture with a solid or liquid carrier and optionally other adjuvants and / or stabilizers to form a base preparation for preparing a personal or home care product, a surface care product, a cleaning product, an air care product, a textile product, an automotive care product, a pet care grooming product or an oral care product, or an edible pet product.
[0076] The present invention therefore also provides in a further aspect a scented product, preferably a scented pet product, comprising the scented composition according to the invention. Preferably, the scented product according to the invention is a personal cosmetic, toiletry and health care product, such as, for example, dry and wet wipes, cleaning solutions, bath additives, shampoos, gels, soaps, mousses, detergent compositions, bath oils, other bath compositions that may be added to a bath, other cleaning compositions that may be applied directly to the skin; leave-on personal care products, including, for example, personal cosmetic, toiletry and health care products, such as, for example, sticks, balms, mousses, sprays, lotions, creams, gels, powders, oils, waxes, fragrances, other personal care products that may be applied to the skin and not rinsed off, or, for example, fabric detergents, fabric softeners. , household or laundry care products such as linen sprays, air care products, candles, sprays, diffusers, tools or other products that may be used in the home for cleaning surfaces, fabrics or scenting the air, as well as automotive care products such as car air fresheners, wipes, cleaners, deodorizers, sprayers, vent clips, aerosols, fabric fresheners, and pet products such as cat litter, cat litter box, cat toys, cat towers, dog toys, dog pads, dog bedding, and pet care grooming products such as pet shampoos, wipes, cleaning products or conditioning products.
[0077] Further perfumed products according to the invention include, for example, perfume extracts, eau de parfum, eau de toilette, shaving lotions, eau de cologne, pre-shave products, splash cologne and perfumed tissue wipes, acidic, alkaline and neutral cleaning agents, for example, floor cleaners, window cleaners, dishwashing detergents, bath and sanitary cleaners, stain remover creams, solid and liquid toilet cleaners, powder and foam carpet cleaners, fabric deodorizers, ironing aids, liquid detergents, powder detergents, pre-laundry products, detergents for cleaning clothes ... These include treatments such as bleaches, soaks and stain removers, laundry softeners, laundry soaps, laundry tablets, disinfectants, surface disinfectants, as well as perfumed air fresheners in liquid or gel form, or solid carriers, aerosol sprays, waxes and polishes such as furniture polishes, floor waxes and shoe polishes, as well as body care products such as bar and liquid soaps, shower gels, shampoos, shaving soaps, shaving foams, bath oils, cosmetic emulsions of the oil-in-water, water-in-oil and water-in-oil-in-water type. hair care products such as hair sprays, hair gels, strengthening hair lotions, hair rinses, permanent and semi-permanent hair dyes, hair shaping agents such as cold wave agents and hair straighteners, hair styling ... and perfumes, hair tonics, hair creams and lotions, deodorants and antiperspirants, e.g., underarm sprays, roll-ons, deodorant sticks, deodorant creams, decorative cosmetic products, e.g., eye shadow, nail polish, makeup, lipstick, mascara, as well as candles, lamp oil, incense, insecticides, insect repellents and fuel, or oral and / or dental care products, e.g., toothpaste, dental gels, dental powders, mouthwashes, chewing gum, and other oral care products.
[0078] In another aspect, the present invention also provides a flavored product, preferably a flavored pet product, comprising the aroma / flavor composition of the present invention. Preferably, the flavored pet product of the present invention is selected from the group consisting of edible pet products. Preferably, the flavored pet product of the present invention is selected from the group consisting of treats, breath products, and oral care products.
[0079] Preferably, the fragrance or aroma / flavor composition of the present invention, preferably a pet fragrance or pet aroma / flavor composition, is included in the final product in an amount sufficient to impart a detectable odor or flavor. Preferably, the fragrance or aroma / flavor composition is included in a total amount ranging from 0.001% to 60% by weight, preferably from 0.01% to 60% by weight, more preferably from 0.1% to 50% by weight, based on the total weight of the scented or flavored product.
[0080] In a final aspect, the present invention provides a method for producing a medicament for the treatment of a pulmonary arthritis, comprising: (i) providing a fragrance composition according to the invention or a scented product according to the invention; (ii) applying a sensory-effective amount of the fragrance composition or scented product to the pet, the product, or the room to obtain a scent acceptable to the pet; A method for scenting a pet, product, or room.
[0081] The present invention will now be described in detail with reference to the following examples, but these examples are merely illustrative of the present invention, and the contents of the present invention are not limited by, and are not limited to, the following examples. [Example]
[0082] The following examples have the purpose of clarifying the invention without thereby limiting it. Example 1 - Acceptance or Rejection of Aroma Compounds
[0083] 1. Method
[0084] Cat comfort test Tests were conducted to determine whether fragrance compositions affect the elimination behavior of cats.
[0085] Twenty cats (four per room) in five rooms were included in the study. Cats were presented with two litter boxes containing two different products (i.e., unscented litter control, non-clumping clay versus experimental litter, and non-clumping clay containing 0.01-0.5% of the fragrance composition).
[0086] Food intake was measured and diet was controlled for each test day by keeping the diet consistent throughout each test period. Litter boxes were changed at the end of each day (24 h), weighed to determine pile weight, and a new litter box was replenished for the second test day. The locations of the two litter boxes were counterbalanced and rotated between the same two locations at the end of each day to account for position bias in the test design. The average pile weight across products was used to determine scent acceptance or rejection.
[0087] Pleasure and discomfort tests in dogs
[0088] Tests were conducted to determine whether the scent compositions were accepted or rejected by dogs.
[0089] At least 32 trained dogs of mixed breeds and sexes were monitored for their interaction with a scent oil applied to an odorless support. The odorless support with the test scent / accord composition was presented to the dogs in a monadic study design. The dogs' spontaneous responses were captured by video recording, and the following behaviors were recorded: sniff latency (the time it took the dog to interact with the sample), the length of time the animal directly sniffed the sample (sniff duration), whether the dog licked the sample (negative behavioral outcome), and / or whether the dog completely rejected the sample (no attempt to sniff). Behavior was coded and analyzed by a trained animal behaviorist. Each study tested two scent / accord compositions and one neutral control (usually water) in a balanced and alternating design.
[0090] The scents were presented to cats and dogs at similar intensities according to the human nose.
[0091] Graph Description
[0092] About cats
[0093] As can be seen in the graph of Figure 1, there is a huge difference between the litter boxes in terms of pile weight. In comparison, the results do not appear to be as significant as those in the graph of Figure 2.
[0094] Actinidia polygama is known to be a cat attractant and has been tested as a positive control. It was used at 0.1% and 1% in cat litter. No significant differences in pile weight were observed.
[0095] Behaviorally, cats explored more in the cat litter with catnip, which suggests that cats can sense it (something is new, the cat comes and discovers it), but it doesn't change their overall elimination behavior. Cats don't mind the catnip smell and use the scented litter just as much as the unscented one.
[0096] To compare the different scents, the logarithm of the p-values is reported on the graph. Bars above the horizontal axis are significant to highly significant for scented cat litter, and bars below the horizontal axis are significant to highly significant for unscented cat litter. Samples in the white / light category are not significant and are therefore accepted by cats as unscented cat litter.
[0097] Figure 3 is an exemplary histogram showing the significance of the weight results in the litter for the jasmine accord (highly significant with the unscented litter selected) and the musk accord (not significant) in the comparison. In the graph of Figure 3, both fragrance / accord comparisons were examined at 0.01.
[0098] About dogs
[0099] The key metric was rejection to determine the dog's acceptance / rejection of the odorant. In each test, a neutral odor was used as a calibrator for dog motivation. The neutral sample was usually water. Rejection is defined as follows: (1) During the 15-second evaluation, the dog shows no interest in approaching the sample; or (2) The dog approaches the sample and immediately turns around in less than one second.
[0100] As shown in Figure 4, the representative example vanillin is well accepted and shows low rejection, whereas the representative example jasmine shows high rejection.
[0101] 2. Summary of cat pleasant and unpleasant results (accepted accords vs. unaccepted accords)
[0102] FIG. 5 is a histogram summarizing the significance of the litter weight results for the scent / accord compositions tested that were accepted and not accepted.
[0103] The accepted or preferred fragrances / accords on this graph that produce higher weight results in scented cat litter all contain at least one of the following: Gourmand scents or gourmand notes (vanillin, Tonkalactone® accord, methoxyethylpyrazine) or - Musk odor or musk notes (Aldoron, Globalide®, ethylene brassylate, lactoscatone).
[0104] The fragrances / accords on this graph that were not accepted and produced more weight results in the unscented litter contained cedarwood oil or orange blossom. Also, the blonde wood and bleach accords were not very accepted but produced more weight results in the unscented litter.
[0105] The average deposition weight for each condition for a single fragrance / accord belonging to the gourmand odor type or gourmand fragrance tone type is shown in Table 4 below.
[0106] [Table 4]
[0107] The mean pile weight of methoxyethylpyrazine cat litter was not significantly different from that of unscented cat litter.
[0108] The mean pile weight of the Red Fruit Accord cat litter was not significantly different from that of the unscented cat litter.
[0109] The mean pile weight in vanilla accord cat litter was not significantly different from that in unscented cat litter.
[0110] The mean pile weight in vanillin litter was not significantly different from that in unscented litter.
[0111] The mean pile weight of Berry Accord cat litter was not significantly different from that of unscented cat litter.
[0112] The mean pile weight of the coconut accord cat litter was not significantly different from that of the unscented cat litter.
[0113] The mean pile weight of Tonkalactone® Accord cat litter was not significantly different from that of unscented cat litter.
[0114] The average deposition weights for each condition for a single fragrance / accord composition belonging to the musk odor type or musk note type are shown in Table 4 below.
[0115] [Table 5]
[0116] The mean pile weight of Aldron cat litter was not significantly different from that of unscented cat litter.
[0117] The mean pile weight in Ambrette-containing cat litter was not significantly different from that in unscented cat litter.
[0118] The average pile weight of lactoskatone cat litter was not significantly different from that of unscented cat litter.
[0119] The mean pile weight of Globanon cat litter was not significantly different from that of unscented cat litter.
[0120] The mean pile weight of cat litter containing Musk Accord (0.01%) was not significantly different from that of unscented cat litter.
[0121] The mean pile weight of the Musk Accord (0.02%) litter was not significantly different from the unscented litter, demonstrating that musk strength had no effect.
[0122] The mean pile weight of the Musk Accord (0.01%) litter was not significantly different from the unscented litter, demonstrating that the test was repeatable.
[0123] The mean pile weight of the Musk Accord (0.02%) litter was not significantly different from the unscented litter (mean pile weight per condition for Musk Accord (0.1%) in different litter bases (sodium bentonite instead of chalk)), demonstrating that the different litter bases did not have an effect on the results (reproducibility).
[0124] The results in Table 1 for gourmand-type substances and Table 2 for musk-type substances, which show no preference in pile weight compared to unscented cat litter, clearly demonstrate that cats are well-accepted of such fragrance / accord substances.
[0125] The average deposition weights for each condition for a single fragrance / accord composition belonging to the woody odor type or woody note type are shown in Table 6 below.
[0126] [Table 6]
[0127] The average weight of the deposits in the cat litter containing cedar occidental oil was significantly different from that in the unscented cat litter.
[0128] The mean pile weight of bleach accord cat litter was significantly different from that of unscented cat litter.
[0129] The mean pile weight of the blond wood cat litter was significantly different from that of the unscented cat litter.
[0130] The mean pile weight of the Jasmine Accord cat litter was significantly different from that of the unscented cat litter.
[0131] The results in Table 3 clearly demonstrate that woody-type accords are poorly accepted by cats and are therefore rejected nuisances.
[0132] Summary of pleasant and unpleasant outcomes (accepted accords) in dogs
[0133] Figure 6 shows examples of scents / accords obtained from dog testing.
[0134] All of the aroma / accord examples shown show a low rejection rate compared to the neutral odor (water) and are therefore well accepted by dogs. The aroma examples tested above the value of the neutral odor (water) are considered very well accepted / preferred by dogs (e.g., ethyl maltol, globalide, vanillin, ethyl vanillin).
[0135] Example 2 - Accepted Fragrance / Accord Compositions
[0136] Example 2.1 - Gourmand-type fragrance / accord composition
[0137] [Table 7]
[0138] Example 2.2 - Musk-type fragrance / accord composition
[0139] [Table 8]
[0140] Example 3 - Unacceptable Fragrance / Accord Compositions
[0141] [Table 9]
Claims
1. A fragrance or aroma / flavor composition comprising: It consists of compounds that give off a gourmand-type odor impression. The compound Vanillin (4-hydroxy-3-methoxybenzaldehyde), Ethyl vanillin (3-ethoxy-4-hydroxybenzaldehyde), Ethyl maltol (2-ethyl-3-hydroxy-4H-pyran-4-one), Coumarin (2H-1-benzopyran-2-one), 3,6-dimethyl-3H-l-benzofuran-2-one, 4-(p-methoxyphenyl)-2-butanone, benzaldehyde, ethyl-2-methyl butyrate, 2-methoxy-3-ethylpyrazine, Delta-decalactone, delta-nonalactone, gamma-octalactone and mixtures thereof; and / or It consists of compounds that give the impression of a musky odor. The compound Aldrone (4-[(6,6-dimethyl-5-bicyclo[2.2.1]heptanyl)methyl]-2-methylcyclohexan-1-one), lactoscatone ((2R,4aR,8aS)-2,8,8-trimethyloctahydro-2H-4a,2-(epoxymethano)naphthalen-10-one), ambrettolide (17-oxacycloheptadec-6-en-1-one), Ethylene brassylate (1,4-dioxacycloheptadecane-5,17-dione), (3E)-oxacyclohexadec-3-en-2-one, Globanone ((8E)-cyclohexadec-8-en-1-one) and mixtures thereof. comprising or consisting of at least one compound or primary sensory component of The fragrance or aroma / flavor composition does not contain jasmine accords including benzyl acetate, dihydrojasmone, hedione, hexyl cinnamic aldehyde alpha and indole.
2. The fragrance composition or aroma / flavor composition is Vanillin (4-hydroxy-3-methoxybenzaldehyde), or 3,6-dimethyl-3H-l-benzofuran-2-one or comprising or consisting of a mixture thereof; or The fragrance composition or aroma / flavor composition is Ambrettolide (17-oxacycloheptadec-6-en-1-one), or (3E)-oxacyclohexadec-3-en-2-one, or globanone ((8E)-cyclohexadec-8-en-1-one), or A fragrance or aroma / flavor composition according to claim 1, comprising or consisting of a mixture of two or three of the aforementioned compounds.
3. The fragrance composition or aroma / flavor composition is Vanillin (4-hydroxy-3-methoxybenzaldehyde), or 3,6-dimethyl-3H-l-benzofuran-2-one, or (3E)-oxacyclohexadec-3-en-2-one, or 2. A fragrance or aroma / flavor composition according to claim 1, comprising or consisting of ethylene brassylate (1,4-dioxacycloheptadecane-5,17-dione), or mixtures thereof.
4. 4. The fragrance or aroma / flavor composition according to claim 1, wherein said at least compounds or major sensory components are present in a total amount ranging from 1 to 100% by weight, based on the total weight of said fragrance or aroma / flavor composition.
5. A fragrance composition or aroma / flavor composition described in any one of claims 1 to 3, wherein the at least one compound or major sensory component is present in a total amount in the range of 40 to 50% by weight based on the total weight of the fragrance composition or aroma / flavor composition.
6. moreover, Methyloctyne carbonate (methyl-non-2-ynoate), Phenylethyiol (2-phenylethan-1-ol), Citronellol (3,7-dimethyloct-6-en-1-ol), lavender oil, peppermint oil, 5. The fragrance or aroma / flavor composition according to any one of claims 1 to 4, comprising one or more additional fragrance substances with a floral odor type impression selected from the group consisting of:
7. moreover, Orange oil, Litsea cubeba oil, Mandarin aldehyde (trans-2-dodecenal), aglunitrile (3,7-dimethyloct-6-enenitrile), Citral (3,7-dimethyl-2,6-octadienal), 6. The fragrance or aroma / flavor composition according to any one of claims 1 to 5, comprising one or more additional fragrance substances with a citrus-type odor impression selected from the group consisting of:
8. A fragrance composition or aroma / flavor composition described in any one of claims 1 to 6, wherein the fragrance composition or aroma / flavor composition is a fragrance composition or aroma / flavor composition for pets, and the pet is a mammal.
9. A fragrance composition or aroma / flavor composition as described in claim 8, wherein the pet is a cat or a dog.
10. A fragrance or aroma / flavour composition according to any one of claims 1 to 8, wherein said fragrance composition is suitable for enjoyment and / or acceptance by cats and / or dogs.
11. Use of a fragrance composition or aroma / flavor composition according to any one of claims 1 to 10 for scented or flavored products.
12. 12. Use of the fragrance or aroma / flavor composition according to claim 11, wherein the scented or flavored product is a scented or flavored pet product.
13. A scented product, comprising a fragrance composition according to any one of claims 1 to 10.
14. 14. The scented product of claim 13, wherein the scented product is selected from the group consisting of personal or home care products, surface care products, cleaning products, air care products, textile products, auto care products, pet care products such as cat litter, cat litter boxes, cat toys, cat towers, dog toys, dog pads, dog bedding, and pet care grooming products or oral care products.
15. A flavored product, comprising an aroma / flavor composition according to any one of claims 1 to 10.
16. The flavored product of claim 15, wherein the flavored product is an edible pet product.
17. 17. The flavored product of claim 16, wherein the edible pet product is selected from the group consisting of treats, breath products, and oral care products.
18. A scented product as described in claim 13 or a flavored product as described in claim 15, wherein the fragrance composition or the aroma / flavor composition is contained in a total amount ranging from 0.001 to 70% by weight based on the total weight of the scented product or flavored product.
19. 19. The scented product of claim 18 or the flavored product of claim 18, wherein the fragrance composition or the aroma / flavor composition is contained in a total amount ranging from 0.1% to 50% by weight, based on the total weight of the scented or flavored product.
20. 1. A method for scenting a pet, product, or room, comprising: (i) providing a fragrance composition according to any one of claims 1 to 10 or a perfumed product according to claim 13 or 14; (ii) applying a sensory effective amount of the fragrance composition or the scented product to the pet, the product, or the room to obtain an odor acceptable to the pet.
Citation Information
Patent Citations
Film / sheet for treating excreta of pet and pet excreta-treating member using the same
JP1997191787A
Feed material
JP2002065098A
Excrement-treating material for animal
JP2006149210A
Fragrance substances
JP2019520452A