Surface plasmon resonance sensor

Abstract

To provide a surface plasmon resonance sensor capable of simultaneous measurement of optical intensity spectrum and optical phase spectrum of SPR dip and obtaining SPR spectrum at high speed with high accuracy.SOLUTION: A surface plasmon resonance (SPR) sensor, having a prism 4 including a metal film 41 provided on a total reflection surface in contact with a sample 5, comprises: optical frequency comb generation means 1; a first wavelength dispersion element 2 diffracting and deflecting the optical frequency comb 1 to be dispersed at an angle according to a wavelength; a first relay lens optical system 3 making incident a beam group angularly dispersed by the first wavelength dispersion element 2 on the total reflection surface of the prism 4 at different angles; a second relay lens optical system 6 making incident the angular dispersion beam group of the optical frequency comb reflected on the total reflection surface at different angles; a second wavelength dispersion element 7 converging the angular dispersion beam group of the optical frequency comb that is made incident in the same direction according to the wavelength; and a spectroscopic part measuring spectrum diffracting or deflecting the second wavelength dispersion element.SELECTED DRAWING: Figure 1

Claims

1. A surface plasmon resonance (SPR) sensor having a prism with a metal film provided on the total reflection surface in contact with the sample, First repetition frequency (f ｒｅｐ１ A first optical frequency comb generating means that generates a first optical frequency comb having ), A first wavelength-dispersing element that diffracts or refracts the first optical frequency comb and disperses it at an angle corresponding to the wavelength, A first relay lens optical system that causes the beam group angle-dispersed by the first wavelength-dispersing element to be incident on the total reflection surface of the prism at different angles, A second relay lens optical system in which angle-dispersed beam groups of the first optical frequency comb that reflected the total reflection surface are incident at different angles, A second wavelength-dispersive element that converges the angle-dispersive beam group of the incident first optical frequency comb in the same direction according to wavelength, A surface plasmon resonance sensor having a spectroscopic unit for measuring the spectrum of the first optical frequency comb obtained by diffracting or refraction of the second wavelength-dispersive element.

2. The spectroscopic unit has a second repetition frequency (f ｒｅｐ２ A surface plasmon resonance sensor according to claim 1, comprising: a second optical frequency comb generating means for generating a second optical frequency comb having ); an interferogram generating unit for generating an interferogram by interfering with the first optical frequency comb; and a complex amplitude SPR spectrum acquisition unit (84) for obtaining a complex amplitude SPR spectrum by performing a Fourier transform on the interferogram.

3. The surface plasmon resonance sensor according to claim 1, characterized in that the metal film is made of one or more metals selected from the group consisting of gold, silver, copper, and aluminum.

4. The surface plasmon resonance sensor according to claim 1, characterized in that the first wavelength-dispersive element comprises a diffraction grating, a prism, or other wavelength-dispersive element.

5. The surface plasmon resonance sensor according to claim 1, characterized in that the second wavelength-dispersive element comprises a diffraction grating, a prism, or other wavelength-dispersive element.

6. The surface plasmon resonance sensor according to claim 1, characterized in that the first relay lens optical system, the prism, and the second relay lens optical system are integrally formed.

7. The first optical frequency comb has a spectrum in the optical communication wavelength band, and the first repetition frequency (f ｒｅｐ１ The surface plasmon resonance sensor according to any one of claims 1 to 6, characterized in that the frequency is 10 MHz or more and 1000 GHz or less, and the bandwidth is 0.1 THz or more and 100 THz or less.

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