SUPEROXIDE DISMUTASE SOLUBLE FIBER COMPOSITIONS
Patent Information
- Application Number
- MX2021014352
- Authority / Receiving Office
- MX · MX
- Patent Type
- Patents
- Current Assignee / Owner
- Priority Date
- 2020-03-20
- Filing Date
- 2021-11-23
- Publication Date
- 2026-02-25
- Estimated Expiration
- 2040-06-10
AI Technical Summary
There is a need for dietary supplements that can increase superoxide dismutase levels in the body, as these levels decrease with age and are compromised by health disorders, and also provide the benefits of soluble fiber, which is often lacking in modern diets, while addressing the limitations of existing antioxidant supplements in absorption and effectiveness.
Compositions comprising superoxide dismutase and soluble fiber, with varying ratios and forms, including powder and gel/liquid formulations, combined with additional components like fruit juices and antioxidants, to enhance absorption and efficacy.
The compositions demonstrate synergistic antioxidant effects, increasing oxygen radical absorbance capacity (ORAC) and providing health benefits such as reduced oxidative stress, inflammation, and improved gut health, with faster recovery from infections and improved symptoms in conditions like diabetes and autoimmune diseases.
Abstract
Description
SUPEROXIDE DISMUTASE SOLUBLE FIBER COMPOSITIONS Field of Invention This description generally relates to compositions comprising superoxide dismutase and a soluble fiber. These compositions can be used as dietary supplements and to improve health and well-being. Background of the Invention Superoxide dismutases (SODs) are a group of metalloenzymes that protect against cellular damage from reactive oxygen species (ROS). SOD catalyzes the dismutation of the superoxide anion (O2~) free radical into molecular oxygen and hydrogen peroxide (H2O2). ROS in cells can damage nucleic acids, proteins, and lipids, leading to decreased cellular function and potential apoptosis. Therefore, the ability to convert ROS into harmless molecules is crucial for protecting cellular function and overall health. Although almost all organisms naturally produce some form of SOD, the levels of SOD produced in cells decline as an individual ages or suffers from certain health conditions. Furthermore, the presence of various pollutants and toxins in the environment can lead to an increase in ROS levels in cells. Therefore, dietary supplementation of produced SOD Ref. 328383 can naturally be important for maintaining health. Another important dietary component is soluble fiber. Soluble fiber absorbs water and forms a gel in the digestive tract. It offers numerous benefits to the gut, including slowing the digestion of certain types of lipids and carbohydrates, which helps prevent the absorption of dietary cholesterol and blood sugar spikes. Soluble fiber is also important for maintaining a healthy gut microbiome, as gut bacteria can ferment some types of soluble fiber. Modern diets are typically low in soluble fiber, and supplements are often necessary to improve overall health. Diabetes mellitus (diabetes) is a common disorder of carbohydrate metabolism. In the United States, more than 30 million people have diabetes. In the past 20 years, the number of adults diagnosed with diabetes has more than tripled as the U.S. population has aged and become more overweight or obese. In people with diabetes, the body's normal ability to use glucose is impaired, leading to elevated blood glucose levels. Diabetes is associated with increased risks of cardiovascular or circulatory diseases or disorders. Fiber, such as soluble fiber, in food has been shown to attenuate the glycemic response to a meal. When fermented by gut bacteria, fiber also produces short-chain fatty acid (SCFA) metabolites that play a role in glucose homeostasis. However, high-fiber foods can cause stomach upset, as can certain fiber supplements. Antioxidants have been shown to have beneficial effects on the human body in combating free radicals, which are implicated in many pathological processes. However, the absorption of effective metabolites of many antioxidants, such as polyphenols, depends on the microbial metabolism of these antioxidants in the gut. Therefore, for many nutritional supplements, these effective polyphenol metabolites are not produced, and the supplement's antioxidant activity is limited. Brief Description of the Invention This description relates to a composition comprising approximately 0.5 units / mg to approximately 500 units / mg of superoxide dismutase and a soluble fiber. In some embodiments of the description, the composition comprises approximately 1 unit / mg to approximately 100 units / mg of superoxide dismutase. In some embodiments of the description, the composition comprises approximately 5 units / mg to approximately 50 units / mg of superoxide dismutase. In some embodiments of the description, the composition comprises approximately 10 units / mg to approximately 15 units / mg of superoxide dismutase. In some embodiments of the description, the composition comprises approximately 14 units / mg of superoxide dismutase. In some formulations, the superoxide dismutase in the composition is extracted from melon, bovine liver, heterotrophic bacteria, or marine phytoplankton. In some formulations, the superoxide dismutase is a copper / zinc superoxide dismutase, an iron / manganese superoxide dismutase, or a nickel superoxide dismutase. In some formulations, the superoxide dismutase in the composition is extracted from a plant. In some formulations, the plant is a fruit, a grain, or a tuber. In some formulations, the plant is a fruit selected from melon, citrus fruit, peach, pear, apple, or banana. In some formulations, the plant is a grain selected from wheat, barley, rye, millet, oats, spelt, bulgur, sorghum, and farro. In some formulations, the plant is a tuber selected from horseradish, potato, yam, sweet potato, cassava, or dahlia. In some versions of the description, the superoxide dismutase in the composition is extracted from an animal. In some versions, the animal is a cow, a pig, a sheep, or a goat. In some versions of the description, the superoxide dismutase in the composition is extracted from a microorganism. In some versions, the microorganism is phytoplankton or bacteria. In some embodiments of the description, the ratio of superoxide dismutase to soluble fiber in the composition is approximately 1:100 to approximately 1:1000 by weight. In some embodiments of the description, the ratio of superoxide dismutase to soluble fiber in the composition is approximately 1:200 to approximately 1:800 by weight. In some embodiments of the description, the ratio of superoxide dismutase to soluble fiber in the composition is approximately 1:300 to approximately 1:700 by weight. In some embodiments of the description, the ratio of superoxide dismutase to soluble fiber in the composition is approximately 1:500 to approximately 1:700 by weight. In some embodiments of the description, the ratio of superoxide dismutase to soluble fiber in the composition is approximately 1:650 to 1:675 by weight. In some formulations, the soluble fiber in the composition is a water-soluble polysaccharide. In some formulations, the soluble fiber in the composition is isolated from corn, wheat, barley, rye, beans, apples, pears, peaches, citrus fruits, berries, peas, rice bran, or oats. In some formulations, the soluble fiber in the composition is selected from soluble corn fiber, inulin, dextrin, guar gum, oligopolysaccharides, galactopolysaccharides, fructooligosaccharides, lactulose, resistant starch, xylooligosaccharides, and isomeltooligosaccharides. In some formulations, the soluble fiber in the composition is soluble corn fiber. In some formulations, the soluble fiber in the composition is resistant maltodextrin. In some embodiments of the description, the composition is in powder form. In some embodiments, the powder composition comprises from approximately 0.1 ppm to approximately 10 ppm of superoxide dismutase by weight. In some embodiments, the powder composition comprises from approximately 0.5 ppm to approximately 5 ppm of superoxide dismutase by weight. In some embodiments, the powder composition comprises from approximately 0.7 ppm to approximately 2 ppm of superoxide dismutase by weight. In some embodiments, the powder composition comprises from approximately 0.8 ppm to approximately 1.2 ppm of superoxide dismutase by weight. In some embodiments, the powder composition comprises from approximately 1% to approximately 90% by weight of soluble fiber. In some embodiments, the powder composition comprises from approximately 1% to approximately 50% by weight of soluble fiber.In some formulations, the powder composition comprises approximately 5% to approximately 25% by weight of soluble fiber. In some formulations, the powder composition comprises approximately 10% to approximately 20% by weight of soluble fiber. In some formulations, the powder composition comprises approximately 12% to approximately 14% by weight of soluble fiber. In some embodiments of the description, the composition is in gel form. In some embodiments of the description, the composition is in liquid form. In some embodiments, the gel or liquid composition comprises from approximately 0.005 mg / mL to approximately 3.0 mg / mL of superoxide dismutase. In some embodiments, the gel or liquid composition comprises from approximately 0.01 mg / mL to approximately 2.0 mg / mL of superoxide dismutase. In some embodiments, the gel or liquid composition comprises from approximately 0.05 mg / mL to approximately 1.0 mg / mL of superoxide dismutase. In some embodiments, the gel or liquid composition comprises from approximately 0.1 mg / mL to approximately 0.5 mg / mL of superoxide dismutase. In some formulations, the gel or liquid composition comprises approximately 50 mg / mL to approximately 1,000 mg / mL of soluble fiber. In some formulations, the gel or liquid composition comprises approximately 70 mg / mL to approximately 500 mg / mL of soluble fiber. In some formulations, the gel or liquid composition comprises MA / a / ZUZI 4Ó0Z contains approximately 90 mg / mL to approximately 250 mg / mL of soluble fiber. In some formulations, the gel or liquid composition comprises approximately 100 mg / mL to approximately 200 mg / mL of soluble fiber. In some embodiments of the description, the composition comprising superoxide dismutase and soluble fiber also includes fruit juice. In some embodiments, the fruit juice is pomegranate juice, red grape juice, cranberry juice, dark sweet cherry juice, sour cherry juice, goji berry juice, acai berry juice, blackberry juice, raspberry juice, strawberry juice, currant juice, blueberry juice, orange juice, grapefruit juice, watermelon juice, beetroot juice, apple juice, lemon juice, lime juice, lychee juice, pineapple juice, prune juice, or combinations thereof.In some formulations, the fruit juice is concentrated pomegranate juice, red grape juice, cranberry juice, dark sweet cherry juice, sour cherry juice, goji berry juice, acai berry juice, blackberry juice, raspberry juice, strawberry juice, currant juice, blueberry juice, orange juice, grapefruit juice, watermelon juice, beet juice, apple juice, lemon juice, lime juice, lychee juice, pineapple juice, prune juice, or combinations thereof. In some formulations, the concentrated fruit juice has approximately 60% to approximately 97% of the juice water removed. In some formulations, the concentrated fruit juice has approximately 85% to approximately 95% of the juice water removed. In some formulations, the composition comprises approximately 5 mg / mL to approximately 200 mg / mL of concentrated fruit juice.In some formulations, the composition comprises approximately 75 mg / mL to approximately 150 mg / mL of concentrated pomegranate juice. In some formulations, the composition comprises approximately 75 mg / mL to approximately 150 mg / mL of concentrated red grape juice. In some formulations, the composition comprises approximately 25 mg / mL to approximately 100 mg / mL of concentrated cranberry juice. In some formulations, the composition comprises approximately 20 mg / mL to approximately 80 mg / mL of concentrated dark sweet cherry juice. In some formulations, the composition comprises approximately 20 mg / mL to approximately 80 mg / mL of concentrated sour cherry juice. In some formulations, the composition comprises approximately 2 mg / mL to approximately 20 mg / mL of concentrated goji berry juice. In some formulations, the composition comprises approximately 2 mg / mL to approximately 20 mg / mL of concentrated acai berry juice. In some embodiments of the description, the composition comprising superoxide dismutase and soluble fiber also includes aloe vera. In some embodiments, the aloe vera is concentrated aloe vera. In some embodiments, the concentrated aloe vera has approximately 60% to approximately 97% of the water removed from the aloe vera. In some embodiments, the composition comprises approximately 2 mg / mL to approximately 20 mg / mL of concentrated aloe vera. In some embodiments of the description, the composition comprising superoxide dismutase and soluble fiber also includes green tea. In some embodiments, the green tea is concentrated green tea. In some embodiments, the concentrated green tea is a green tea extract. In some embodiments, the composition comprises from approximately 2 mg / mL to approximately 20 mg / mL of concentrated green tea. In some embodiments of the description, the composition comprising superoxide dismutase and soluble fiber also includes resveratrol. In some embodiments, the composition comprises from approximately 0.5 mg / mL to approximately 6 mg / mL of resveratrol. In some embodiments of the description, the gel composition comprising superoxide dismutase and soluble fiber also comprises carboxymethylcellulose. In some embodiments, the composition comprises from approximately 0.5 to approximately 5.0 mg / mL of carboxymethylcellulose. In some embodiments of the description, the gel composition comprising superoxide dismutase and soluble fiber also comprises xanthan gum. In some embodiments, the composition comprises from approximately 0.5 to approximately 5.0 mg / mL of xanthan gum. The present description also relates to a composition comprising: a) from approximately 0.5 units / mg to approximately 100 units / mg of superoxide dismutase; b) a soluble fiber; and c) at least two fruit juices selected from pomegranate juice, red grape juice, cranberry juice, dark sweet cherry juice, sour cherry juice, goji berry juice, and acai berry juice. In some embodiments, the composition comprises at least three fruit juices. In some embodiments, the composition comprises at least four fruit juices. In some embodiments, the composition comprises at least five fruit juices. In some embodiments, the composition comprises at least six fruit juices. In some embodiments, the composition comprises pomegranate juice, red grape juice, cranberry juice, dark sweet cherry juice, sour cherry juice, goji berry juice, and acai berry juice. In some formulations, the fruit juices are concentrated fruit juices. In some formulations, the soluble fiber is soluble corn fiber. In some formulations, the soluble corn fiber is resistant to digestion maltodextrin. The present description also relates to a composition comprising: a) superoxide dismutase; b) soluble corn fiber; c) at least two fruit juices selected from pomegranate juice, red grape juice, cranberry juice, dark sweet cherry juice, sour cherry juice, goji berry juice, and acai berry juice; d) aloe vera; e) green tea; and f) resveratrol. In some embodiments, the composition comprises at least three fruit juices. In some embodiments, the composition comprises at least four fruit juices. In some embodiments, the composition comprises at least five fruit juices. In some embodiments, the composition comprises at least six fruit juices. In some embodiments, the composition comprises pomegranate juice, red grape juice, cranberry juice, dark sweet cherry juice, sour cherry juice, goji berry juice, and acai berry juice. In some formulations, the fruit juices are concentrated fruit juices. In some formulations, the soluble corn fiber is digestion-resistant maltodextrin. In some formulations, the formulation also includes carboxymethylcellulose. In some formulations, the formulation also includes xanthan gum. The present description also relates to a composition comprising: a) from approximately 30 units to approximately 1,000 units of superoxide dismutase; b) from approximately 50 mg / mL to approximately 200 mg / mL of a soluble corn fiber; c) from approximately 5 mg / mL to approximately 200 mg / mL each of at least two concentrated fruit juices selected from pomegranate juice, red grape juice, cranberry juice, dark sweet cherry juice, sour cherry juice, goji berry juice, and acai berry juice; d) from approximately 2 mg / mL to approximately 20 mg / mL of concentrated aloe vera; e) from approximately 2 mg / mL to approximately 20 mg / mL of concentrated green tea; and f) from approximately 0.5 mg / mL to approximately 6 mg / mL of resveratrol. In some formulations, the soluble corn fiber is digestion-resistant maltodextrin. In some formulations, the formulation also comprises approximately 0.5 to approximately 5.0 mg / mL of carboxymethylcellulose. In some formulations, the formulation also comprises approximately 0.5 to approximately 5.0 mg / mL of xanthan gum. In embodiments of any of the compositions described herein, the composition has an oxygen radical absorbance capacity (ORAC) greater than 1,000 pmol / g of the composition. In embodiments of any of the compositions described herein, the composition has an ORAC greater than 1,500 pmol / g of the composition. In embodiments of any of the compositions described herein, the ORAC value for the composition is at least 1.5 times greater than the sum of the individual ORAC values for each component of the MA / a / ZUZI 4Ó0Z composition. In any of the compositions described herein, an ORAC value for the composition is at least 1.6 times greater than the sum of the individual ORAC values for each component of the composition. This description also relates to a method for reducing the number of oxygen free radicals in a mammal, comprising administering to the mammal any of the compositions described herein. In some embodiments of the method, the oxygen free radicals to be reduced are peroxyl radicals, hydroxyl radicals, peroxynitrite, superoxide anion, singlet oxygen, hypochlorite, or combinations thereof. The present description also relates to a method for reducing inflammation in a mammal, comprising administering to the mammal any of the compositions described herein. The present description also relates to a method for reducing viral symptoms in a mammal, comprising administering to the mammal any of the compositions described herein. In the methods described herein, the composition is administered to the mammal once daily. In the methods described herein, the composition is administered to the mammal twice daily. In the methods described herein, the mammal is a human. Brief Description of the Figures Figure 1 is a graph of viscosity (equilibrium) versus shear rate (1 / s) for two 5 mL samples of the gel formulation from Example 1, as tested in Example 3 - open circles: sample 1; closed circles: sample 2. Detailed Description of the Invention This description provides compositions comprising superoxide dismutase and soluble fiber. The compositions described herein may be used as supplements to increase superoxide dismutase and soluble fiber levels in a patient. As described herein, the compositions may also include additional components, such as antioxidants, vitamins, or other nutrients, along with excipients and other formulation agents. It should be noted that the specific implementations shown and described herein are examples and are not intended to limit the scope of the request in any other way. Published patents, patent applications, websites, company names, and scientific literature referenced herein are incorporated by reference in their entirety to the same extent as if each were specifically and individually indicated as being referenced. Any conflict between any reference cited herein and the specific teachings of this description shall be resolved in favor of the latter. Likewise, any conflict between a definition understood in the art of a word or phrase and a definition of the word or phrase as specifically set forth in this description shall be resolved in favor of the latter. As used herein, "un" or "una" can mean one or more. As used herein, when used with the word it comprises, the words "un" or "una" can mean one or more. As used herein, "otro" or "desidera" can mean at least one or more. Throughout this application, the term "approximately" is used to indicate that a value includes the inherent variation due to error in the method / device used to determine the value, or the variation that exists among study patients. Typically, the term "approximately" is intended to encompass approximately or less than 1%, 2%, 3%, 4%, 5%, 6%, 7%, 8%, 9%, 10%, 11%, 12%, 13%, 14%, 15%, 16%, 17%, 18%, 19%, or 20% variability, depending on the situation. The use of the term "or" in the claims is used to mean "and / or," unless explicitly stated, to refer only to alternatives or the alternatives are mutually exclusive, although the description supports a definition that refers only to alternatives and / or. As used herein, the terms comprising (and any variant or form of comprising, such as comprising and comprising), having (and any variant or form of having, such as having and has), including (and any variant or form of including, such as including and including) or containing (and any variant or form of containing, such as containing and containing) are inclusive or open and do not exclude additional, unquoted method elements or steps. The use of the term for example and its corresponding abbreviation e.g. (whether in italics or not) means that the specific terms cited are representative examples and modalities of the description that are not intended to be limited to the specific examples referenced or cited, unless explicitly stated otherwise. The technical and scientific terms used herein have the meaning commonly understood by a person skilled in the art to which this application pertains, unless otherwise defined. This document refers to several methodologies and materials known to those experienced in the technique. The term superoxide dismutase (sometimes abbreviated SOD), as used herein, refers to an enzyme that catalyzes the dismutation of the superoxide anion (O₂⁻) free radical into molecular oxygen and hydrogen peroxide (H₂O₂). Superoxide dismutase has the enzyme classification (EC) number 1.15.1.1. Superoxide dismutase is an important component in protecting cells from damage by reactive oxygen species (ROS), such as O₂⁻, which are formed during cellular oxygen metabolism. Superoxide dismutase thus acts as an important antioxidant and is present in almost all types of cellular organisms. However, particularly in complex organisms such as mammals, cellular levels of superoxide dismutase decline as the organism ages, making it more susceptible to cellular damage from reactive oxygen species. The term soluble fiber, as used herein, refers to any type of dietary fiber that dissolves in water. When consumed, soluble fiber absorbs water to form a gel in the gut, which helps slow the metabolism of lipids and carbohydrates. Soluble fiber is also a prebiotic that can be fermented by gut bacteria, helping to maintain a healthy gut microbiome. The term antioxidant, as used herein, refers to a substance that significantly reduces the adverse effects of reactive species, such as reactive oxygen and nitrogen species, by totally or partially neutralizing them. Antioxidants can be classified as primary and secondary antioxidants. Primary antioxidants delay or inhibit the initiation stage of oxidation, while secondary antioxidants reduce oxidation by scavenging the substrate or quenching oxygen free radicals. Superoxide dismutase and soluble fiber The formulations and compositions described herein comprise a quantity of superoxide dismutase measured in activity units per mg of protein. For enzyme activity, one unit (U) (expressed in pmol / min) is defined as the amount of enzyme that catalyzes the conversion of one micromole of substrate per minute under specified conditions. Superoxide dismutase activity units can be measured by any known method. For example, methods for determining superoxide dismutase activity in units are described in McCord, JM and Fridovich, I., J. Biol. Chem. 1969, 244: 6049-6055; Weydert et al., Nature Protocols 2010, 5(1): 51-66; and in the technical protocol at https: / / www.sigmaaldrich.com / technicaldocuments / protocols / biology / enzymatic-assay-of-superoxidedismutase.html; The descriptions of each of which are incorporated herein by reference.In modalities, a unit of superoxide dismutase activity is defined as the amount of superoxide dismutase that will inhibit the reduction rate of cytochrome c by 50% in a coupled system, using xanthine and xanthine oxidase at pH 7.8 at 25°C in a concentration of 3.0 mL reaction volume. In some forms, the compositions described herein comprise high concentrations of superoxide dismutase, for example, more than 0.5 units / mg, more than 0.1 units / mg, more of 1 unit / mg, more than 10 units / mg, more than 50 units / mg, more than 100 units / mg, more than 200 units / mg, more than 500 units / mg, more than 1,000 units / mg, more than 2,000 units / mg, more than 2,500 units / mg, more than 3,000 units / mg, more than 4,000 units / mg or more than 5,000 units / mg of superoxide dismutase, and a soluble fiber. In various embodiments, the compositions described herein comprise from approximately 5 units / mg to approximately 5,000 units / mg, from approximately 5 units / mg to approximately 4,000 units / mg, from approximately 5 units / mg to approximately 3,000 units / mg, or from approximately 5 units / mg to approximately 2,000 units / mg of superoxide dismutase and a soluble fiber. In various embodiments, the compositions comprise from approximately 1 unit / mg to approximately 1,000 units / mg, from approximately 1 unit / mg to approximately 750 units / mg, from approximately 1 unit / mg to approximately 500 units / mg, or from approximately 1 unit / mg to approximately 250 units / mg. In various embodiments, the compositions described herein comprise from approximately 0.5 units / mg to approximately 100 units / mg of superoxide dismutase and a soluble fiber.In some formulations, the compositions comprise from approximately 1 unit / mg to approximately 50 units / mg of superoxide dismutase. In some formulations, the compositions comprise from approximately 5 units / mg to approximately 25 units / mg of superoxide dismutase. In some formulations, the compositions comprise from approximately 10 units / mg to approximately 15 units / mg of superoxide dismutase. In some formulations, the compositions comprise approximately 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, or 30 units / mg of superoxide dismutase. In some formulations, the compositions comprise approximately 14 units / mg of superoxide dismutase. The superoxide dismutase used in the compositions described herein can be obtained from any enzyme source. In some forms, superoxide dismutase is extracted from melon, bovine liver, heterotrophic bacteria, or marine phytoplankton. The superoxide dismutase can also be any type of enzyme. In some forms, the superoxide dismutase is a copper / zinc superoxide dismutase, an iron / manganese superoxide dismutase, or a nickel superoxide dismutase. In some formulations, superoxide dismutase is extracted from a plant. In some formulations, the plant is a fruit, a grain, or a tuber. In some formulations, the plant is a fruit selected from melon, citrus fruit, peach, pear, apple, or banana. In some formulations, the plant is a grain selected from wheat, barley, rye, millet, oats, spelt, bulgur, sorghum, and farro. In some formulations, the plant is a tuber selected from horseradish, potato, yam, sweet potato, cassava, or dahlia. In some cases, superoxide dismutase is extracted from an animal. In some cases, the animal is a cow, a pig, a sheep, or a goat. In some versions, superoxide dismutase is extracted from a microorganism. In some versions, the microorganism is either phytoplankton or bacteria. In some versions, the microorganism is a heterotrophic bacterium, for example, a bacterium that obtains the sugars it needs for energy production from its environment. The superoxide dismutase to soluble fiber ratio can be adjusted as needed by varying the amount of one or both components of the composition. In some formulations, the superoxide dismutase to soluble fiber ratio in the composition is approximately 1:100 to approximately 1:1,000 by weight. In some formulations, the superoxide dismutase to soluble fiber ratio in the composition is approximately 1:200 to approximately 1:800 by weight. In some formulations, the superoxide dismutase to soluble fiber ratio in the composition is approximately 1:300 to approximately 1:700 by weight. In some formulations, the superoxide dismutase to soluble fiber ratio in the composition is approximately 1:500 to approximately 1:700 by weight. In some formulations, the superoxide dismutase to soluble fiber ratio in the composition is approximately 1:650 to 1:675 by weight. In some of the formulations described herein, various types of soluble fiber may be used, including mixtures of two, three, four, five, six, or more different types of soluble fiber. In some formulations, soluble fiber is a water-soluble polysaccharide. In some formulations, soluble fiber is isolated from corn, wheat, barley, rye, beans, apples, pears, peaches, citrus fruits, berries, peas, rice bran, or oats. In some formulations, soluble fiber is selected from soluble corn fiber, inulin, dextrin, guar gum, oligopolysaccharides, galactopolysaccharides, fructooligosaccharides, lactulose, resistant starch, xylooligosaccharides, and isomeltooligosaccharides. In some formulations, the soluble fiber is soluble corn fiber. In some formulations, the soluble fiber is resistant maltodextrin. In terms of modalities, the soluble fiber is Fibersol-2®, as sold by Archer Daniels Midland Company and Matsutani Chemical Industry Co., Ltd.In some forms, soluble fiber is an alternative type of Fibersol-2®, such as Fibersol-2AG. Fibersol-LQ, Fibersol-2L, Fibersol-DLQ, or Fibersol GMO-free. Powder compositions In some formulations of the compositions described herein, the composition is in powder form. In formulations where the composition is in powder form, it may be consumed as a dry powder or added to a beverage or food. In other formulations, the powder is mixed with water, a sports drink, a protein shake, juice, tea, coffee, milk, kefir, ice cream, yogurt, a smoothie, broth, or soup before consumption. In some formulations, the powder composition comprises a high concentration of superoxide dismutase by weight, for example, more than 0.1 ppm, more than 0.5 ppm, more than 1 ppm, more than 2 ppm, more than 5 ppm, more than 10 ppm, more than 20 ppm, more than 50 ppm, more than 100 ppm, more than 200 ppm, more than 300 ppm, more than 400 ppm, or more than 500 ppm. In some formulations, the powder composition comprises from approximately 0.1 ppm to approximately 10 ppm of superoxide dismutase by weight. In some formulations, the powder composition comprises from approximately 0.5 ppm to approximately 5 ppm of superoxide dismutase by weight. In some formulations, the powder composition comprises from approximately 0.7 ppm to approximately 2 ppm of superoxide dismutase by weight. In some formulations, the powder composition comprises from approximately 0.8 ppm to approximately 1.2 ppm of superoxide dismutase by weight. In various forms, the powder composition comprises approximately 0.1, 0.25, 0.5, 0.75, 1.0, 1.1, 1.2, 1.25, 1.3, 1.4, 1.5, 1.6, 1.7, 1.75, 1.8, 1.9, 2.0, 2.25, 2.5, 2.75, 3.0, 3.25, 3.5, 3.75, 4.0, 4.25, 4.5, 4.75, 5.0, 5.25, 5.5, 5.75, 6.0, 6.25, 6.5, 6.75, 7.0, 7.25, 7.5, 7.75, 8.0, 8.25, 8.5, 8.75, 9.0, 9.25, 9.5, 9.75 or 10.0 ppm of superoxide dismutase by weight. In some forms, the powder composition comprises approximately 1% to approximately 90% by weight of soluble fiber. In some forms, the powder composition comprises approximately 1% to approximately 50% by weight of soluble fiber. In some forms, the powder composition comprises approximately 5% to approximately 25% by weight of soluble fiber. In some forms, the powder composition comprises approximately 10% to approximately 20% by weight of soluble fiber. In some forms, the powder composition comprises approximately 12% to approximately 14% by weight of soluble fiber. In various forms, the energy composition comprises approximately 1%, 2%, 3%, 4%, 5%, 6%, 7%, 8%, 9%, 10%, 11%, 12%, 13%, 14%, 15%, 16%, 17%, 18%, 19%, 20%, 21%, 22%, 23%, 24%, 25%, 26%, 27%, 28%, 29%, or 30% soluble fiber by weight. Available in liquid or gel form. In some of the formulations described herein, the composition is in gel form. In other formulations, the composition is in liquid form. In formulations where the composition is in gel or liquid form, it can be consumed directly in that form. In other formulations, the gel or liquid can be added to a beverage or food. In some formulations, the powder is mixed with water, a sports drink, a protein shake, juice, tea, coffee, milk, kefir, ice cream, yogurt, a smoothie, broth, or soup before consumption. In some formulations, the gel or liquid composition comprises approximately 0.005 mg / mL to approximately 5.0 mg / mL of superoxide dismutase. In some formulations, the gel or liquid composition comprises approximately 0.01 mg / mL to approximately 2.5 mg / mL of superoxide dismutase. In some formulations, the gel or liquid composition comprises approximately 0.05 mg / mL to approximately 1.0 mg / mL of superoxide dismutase. In some formulations, the gel or liquid composition comprises approximately 0.1 mg / mL to approximately 0.5 mg / mL of superoxide dismutase. In various formulations, the gel or liquid composition comprises approximately 0.005, 0.01, 0.05, 0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, 1.0, 1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.8, 1.9, 2.0, 2.1, 2.2, 2.3, 2.4, 2.5, 2.6, 2.7, 2.8, 2.9 or 3.0 mg / mL of superoxide dismutase. In some formulations, the gel or liquid composition comprises approximately 50 mg / mL to approximately 1,000 mg / mL of soluble fiber. In some formulations, the gel or liquid composition comprises approximately 70 mg / mL to approximately 500 mg / mL of soluble fiber. In some formulations, the gel or liquid composition comprises approximately 90 mg / mL to approximately 250 mg / mL of soluble fiber. In some formulations, the gel or liquid composition comprises approximately 100 mg / mL to approximately 200 mg / mL of soluble fiber. In various forms, the gel or liquid composition comprises approximately 50, 75, 100, 110, 120, 125, 130, 133, 135, 140, 150, 160, 170, 175, 180, 190, 200, 225, 250, 275, 300, 325, 350, 375, 400, 425, 450, 475 or 500 mg / mL of soluble fiber. Fruit juices In the formulations described herein, the composition comprising superoxide dismutase and soluble fiber also includes fruit juice. The fruit juice may contribute additional antioxidants, soluble fiber, insoluble fiber, vitamins, and nutrients to the composition. In some varieties, the fruit juice is pomegranate juice, red grape juice, cranberry juice, dark sweet cherry juice, sour cherry juice, goji berry juice, acai berry juice, blackberry juice, raspberry juice, strawberry juice, currant juice, blueberry juice, orange juice, grapefruit juice, watermelon juice, beet juice, apple juice, lemon juice, lime juice, lychee juice, pineapple juice, prune juice, or combinations thereof. In various forms, the composition comprises two, three, four, five or six types of juice selected from: pomegranate juice, red grape juice, cranberry juice, dark sweet cherry juice, sour cherry juice, goji berry juice, acai berry juice, blackberry juice, raspberry juice, strawberry juice, currant juice, blueberry juice, orange juice, grapefruit juice, watermelon juice, beetroot juice, apple juice, lemon juice, lime juice, lychee juice, pineapple juice and plum juice. In some forms, fruit juice can be concentrated, for example, by removing some of the water from the original juice. Examples of fruit juice include concentrated pomegranate juice, red grape juice, cranberry juice, dark sweet cherry juice, sour cherry juice, goji berry juice, acai berry juice, blackberry juice, raspberry juice, strawberry juice, currant juice, cranberry juice, orange juice, grapefruit juice, watermelon juice, beet juice, apple juice, lemon juice, lime juice, lychee juice, pineapple juice, prune juice, or combinations thereof.In various formulations, the composition comprises two, three, four, five, or six types of concentrated juice selected from: concentrated pomegranate juice, concentrated red grape juice, concentrated cranberry juice, concentrated dark sweet cherry juice, concentrated sour cherry juice, concentrated goji berry juice, concentrated acai berry juice, concentrated blackberry juice, concentrated raspberry juice, concentrated strawberry juice, concentrated gooseberry juice, concentrated blueberry juice, concentrated orange juice, concentrated grapefruit juice, concentrated watermelon juice, concentrated beetroot juice, concentrated apple juice, concentrated lemon juice, concentrated lime juice, concentrated lychee juice, concentrated pineapple juice, and concentrated prune juice. In various formulations, the concentrated fruit juice has approximately 60% to approximately 97% of its water content removed.In some varieties, concentrated fruit juice has approximately 85% to 95% of its water removed. In other varieties, concentrated fruit juice has approximately 60%, 65%, 70%, 75%, 80%, 85%, 90%, 95%, 96%, 97%, 98%, or 99% of its water removed. Water can be removed from fruit juices using any known method for concentrating fruit juices. In some formulations, the composition comprises approximately 5 mg / mL to approximately 200 mg / mL of concentrated fruit juice. In some formulations, the composition comprises approximately 75 mg / mL to approximately 150 mg / mL of concentrated pomegranate juice. In some formulations, the composition comprises approximately 75 mg / mL to approximately 150 mg / mL of concentrated red grape juice. In some formulations, the composition comprises approximately 25 mg / mL to approximately 100 mg / mL of concentrated cranberry juice. In some formulations, the composition comprises approximately 20 mg / mL to approximately 80 mg / mL of concentrated dark sweet cherry juice. In some formulations, the composition comprises approximately 20 mg / mL to approximately 80 mg / mL of concentrated sour cherry juice. In some formulations, the composition comprises approximately 2 mg / mL to approximately 20 mg / mL of concentrated goji berry juice.In various formulations, the composition comprises approximately 2 mg / mL to approximately 20 mg / mL of concentrated acai berry juice. Other additional components. In the formulations described herein, the formulation comprising superoxide dismutase and soluble fiber also includes aloe vera. Aloe vera may contribute additional antioxidants, soluble fiber, insoluble fiber, vitamins, and nutrients to the formulation. In some formulations, aloe vera is concentrated aloe vera. In some formulations, aloe vera can be concentrated, for example, by removing some of the water extracted from the aloe vera plant. In some formulations, concentrated aloe vera contains approximately 60% to 97% of the water removed from the aloe vera. Specifically, the concentration of concentrated aloe vera ranges from approximately 2 mg / mL to approximately 20 mg / mL. In the formulations described herein, the formulation comprising superoxide dismutase and soluble fiber also includes green tea. The green tea may contribute additional antioxidants, vitamins, and nutrients to the formulation. In some formulations, the green tea is concentrated green tea. In some formulations, the concentrated green tea is a green tea extract made from green tea leaves or green tea powder. In some formulations, the green tea is added to the composition in powder form. In some formulations, the composition comprises approximately 2 mg / mL to approximately 20 mg / mL of concentrated green tea. In the formulations described herein, the composition comprising superoxide dismutase and soluble fiber also includes resveratrol. The resveratrol may provide additional antioxidants to the composition. In some formulations, the composition comprises from approximately 0.5 mg / mL to approximately 6 mg / mL of resveratrol. Excipients / Formulations In certain formulations, the compositions described herein may be combined with one or more excipients. In certain formulations, the excipient may be a gelling agent, a thickening agent, a carrier, a buffer, or a filler. In certain formulations, the compositions described herein may be formulated in beverages or food products. In certain formulations, the compositions may be formulated in juice, a hydrating beverage (e.g., a sports drink), a protein shake, tea, coffee, milk, kefir, ice cream, yogurt, a smoothie, broth, or soup. In some embodiments, the compositions comprise the thickener / gelling agent carboxymethylcellulose. In some embodiments, the composition is a gel comprising superoxide dismutase, soluble fiber, and carboxymethylcellulose. In some embodiments, the composition comprises from approximately 0.5 to approximately 5.0 mg / mL of carboxymethylcellulose. In some embodiments, the compositions comprise the thickener / gelling agent xanthan gum. In some embodiments, the composition is a gel comprising superoxide dismutase, soluble fiber, and xanthan gum. In some embodiments, the composition comprises from approximately 0.5 to approximately 5.0 mg / mL of xanthan gum. In certain embodiments, the composition comprises: a) from approximately 0.5 units / mg to approximately 100 units / mg of superoxide dismutase; b) a soluble fiber; and c) at least two fruit juices selected from pomegranate juice, red grape juice, cranberry juice, dark sweet cherry juice, sour cherry juice, goji berry juice, and acai berry juice. In certain embodiments, the composition comprises at least three fruit juices. In certain embodiments, the composition comprises at least four fruit juices. In certain embodiments, the composition comprises at least five fruit juices. In certain embodiments, the composition comprises at least six fruit juices. In certain embodiments, the composition comprises pomegranate juice, red grape juice, cranberry juice, dark sweet cherry juice, sour cherry juice, goji berry juice, and acai berry juice. In certain embodiments of the composition, the fruit juices are concentrated fruit juices.In some formulations, the soluble fiber is soluble corn fiber. In others, the soluble corn fiber is digestion-resistant maltodextrin. In some embodiments, the composition comprises: a) superoxide dismutase; b) soluble corn fiber; c) at least two fruit juices selected from pomegranate juice, red grape juice, cranberry juice, dark sweet cherry juice, sour cherry juice, goji berry juice, and acai berry juice; d) aloe vera; e) green tea; and f) resveratrol. In some embodiments, the composition comprises at least three fruit juices. In some embodiments, the composition comprises at least four fruit juices. In some embodiments, the composition comprises at least five fruit juices. In some embodiments, the composition comprises at least six fruit juices. In some embodiments, the composition comprises pomegranate juice, red grape juice, cranberry juice, dark sweet cherry juice, sour cherry juice, goji berry juice, and acai berry juice. In some embodiments of the composition, the fruit juices are concentrated fruit juices.In some formulations, the soluble corn fiber is digestion-resistant maltodextrin. In some formulations, the formulation also includes carboxymethylcellulose. In some formulations, the formulation also includes xanthan gum. In certain embodiments, the composition comprises: a) from approximately 30 units to approximately 1,000 units of superoxide dismutase; b) from approximately 50 mg / mL to approximately 200 mg / mL of soluble corn fiber; c) from approximately 5 mg / mL to approximately 200 mg / mL each of at least two concentrated fruit juices selected from pomegranate juice, red grape juice, cranberry juice, dark sweet cherry juice, sour cherry juice, goji berry juice, and acai berry juice; d) from approximately 2 mg / mL to approximately 20 mg / mL of concentrated aloe vera; e) from approximately 2 mg / mL to approximately 20 mg / mL of concentrated green tea; and f) from approximately 0.5 mg / mL to approximately 6 mg / mL of resveratrol. In certain embodiments of the composition, the soluble corn fiber is digestion-resistant maltodextrin. In some forms, the composition also comprises approximately 0.5 to approximately 5.0 mg / mL of carboxymethylcellulose.In some forms, the composition also comprises approximately 0.5 to approximately 5.0 mg / mL of xanthan gum. In some embodiments, the present invention provides a liquid nutritional formulation containing soluble fiber and a plurality of antioxidants. In some formulations, soluble corn fiber is included. Corn fiber may constitute approximately 1 to approximately 5 percent by weight of the total formulation. Corn fiber may be presented in the form of a dry powder. In some formulations, the soluble fiber may be a prebiotic, digestion-resistant maltodextrin fiber derived from corn (Fibersol-2). A prebiotic is a selectively fermented ingredient that induces specific changes in both the composition and activity of the gut microbiota, conferring health benefits. In some formulations, the antioxidants include various polyphenols. Polyphenols may constitute approximately 1 to approximately 3 percent by weight of the total formulation. In some formulations, the antioxidants include superoxide dismutases (SOD). In some forms, the present description provides a nutritional supplement formulation containing soluble corn fiber, concord red grape juice concentrate (Vitis labrusca), pomegranate juice concentrate (Punica granatum), cranberry juice concentrate (Vaccinium corymbosum), dark sweet cherry juice concentrate (Prunus avium juice concentrate), sour cherry juice concentrate (Prunus cerasus), berry juice concentrate (Lycium barbarum), acai berry juice concentrate (Euterpe oleracea), aloe vera juice concentrate (Aloe barbadensis Mill.), green tea extract (Camellia sinensis), resveratrol, melon juice concentrate (Cucumis melo L. and Extramel-SOD). The soluble fiber and antioxidant formulations described here provide synergistic effects in that the soluble prebiotic fiber acts as a fertilizer for the bacteria in the colon, while the polyphenols are substantially absorbed in the colon and subject to extensive catabolism by the colonic microbiota. The presence of prebiotic fiber enhances the activity of the colonic microbiota, leading to more efficient absorption of polyphenols in the colon. A large majority of the polyphenols in an antioxidant supplement end up in the large intestine, where they undergo microbial metabolism into their active metabolites, which can then exert an antioxidant effect. Soluble fiber modulates the intestinal microbes and maximizes the metabolism of polyphenols, producing numerous antioxidant, anti-inflammatory, and anti-infective effects. In some forms, the composition comprises the ingredients shown in Table 1 in the indicated quantities. Table 1 Antioxidant composition Revivify YES. # Proprietary Blend 17.88 g Amount / mg 1 Soluble Corn Fiber (Fibersol-2) 4,000 2 Pomegranate Juice Concentrate 4,000 3 Concord Grape Juice Concentrate 4,000 4 Cranberry Juice Concentrate 2,000 5 Dark Sweet Cherry Juice Concentrate 1,450 6 Sour Cherry Juice Concentrate 1,450 7 Goji Pulp 294 8 Acai Juice Concentrate 200 9 Aloe Vera Juice 200 10 Green Tea 200 11 Resveratrol 80 12 Extramel SOD (14,000 units / g) 6 13 CMC 60.5 14 Xanthan Gum 60.5 15 Water q.s. (30 mL) Reactive oxygen species and oxygen radical absorption capacity In some forms, the compositions described herein are useful for reducing the level of reactive oxygen species (ROS) in cells. The reactive oxygen species reduced in levels include one or more species of peroxide, superoxide, hydroxyl radical, singlet oxygen, and alpha oxygen. In some forms, the reactive oxygen species reduced in levels include one or more of a peroxyl radical, hydroxyl radical, peroxynitrite, superoxide anion, singlet oxygen, or hypochlorite species. The description reports the discovery that compositions comprising superoxide dismutase in combination with soluble fiber result in a significantly increased oxygen radical absorbance capacity (ORAC). The addition of soluble fiber to a composition comprising superoxide dismutase provides a synergistic effect in increasing the oxygen radical absorbance capacity; that is, the ORAC value of the combination is much higher than the additive value of superoxide dismutase and soluble fibers alone. In some forms, the ability of a composition described herein to reduce the level of reactive oxygen species in cells is measured by measuring the oxygen radical absorbance capacity (ORAC) of the composition. Examples of ORAC tests are known in the field. See, for example, Chapter 2 - Methods for Measuring Oxidative Stress in the Laboratory by A. Dasgupta et al., pp. 19-40 of Antioxidants in Food, Vitamins and Supplements (2014). Elsevier), which is incorporated herein by reference. In general, the ORAC test measures the antioxidant capacity of a substance. The ORAC test measures a fluorescent signal from a probe that turns off in the presence of reactive oxygen species. A reactive oxygen species inducer is introduced into the test system. The inducer triggers the release of a specific reactive oxygen species, which would degrade the probe and cause a change in the wavelength or intensity of its emission. Antioxidant materials present in the test absorb the reactive oxygen species and protect the probe from degradation. The degree of preservation of the probe thus indicates the antioxidant capacity of the material. In some modalities, the fluorescent probe used in the ORAC test is either beta-phycoerythrin or fluorescein. In some modalities, the ORAC capacity of an antioxidant is measured against a standard. In some modalities, the standard is the well-known antioxidant Trolox® (6-hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid), which is a vitamin E analogue. In modalities where Trolox® is used as the standard, the results can be expressed as the Total Antioxidant Capacity (TAC) for the tested molecule and expressed as micromoles (pmol) of Trolox® equivalence (TE) per gram of the tested antioxidant molecule. In some versions, the ORAC test measures one or more of the following reactive oxygen species: peroxyl radicals, hydroxyl radicals, peroxynitrite, superoxide dismutase, singlet oxygen, and hypochlorite. In one version, the ORAC test is the ORAC 6.0 test performed by Brunswick Laboratories in Southborough, MA, USA. The ORAC 6.0 test assesses antioxidant capacity against peroxyl radicals, hydroxyl radicals, peroxynitrite, superoxide dismutase, singlet oxygen, and hypochlorite. In embodiments of any of the compositions described herein, the composition has a total ORAC greater than 1,000 pmol / g of composition. In embodiments of any of the compositions described herein, the composition has an ORAC greater than 1,500 pmol / g of composition. In embodiments of any of the compositions described herein, the composition has a total ORAC greater than 700, 800, 900, 1,000, 1,100, 1,200, 1,300, 1,400, 1,500, 1,600, 1,700, 1,800, 1,900, or 2,000 pmol / g of composition. As used herein, total ORAC refers to the sum of the ORAC value for each reactive oxygen species. For example, in modalities where the ORAC 6.0 test is used, total ORAC is the sum of the ORAC values for each of the peroxyl radicals, hydroxyl radicals, peroxynitrite, superoxide dismutase, singlet oxygen, and hypochlorite.In modalities, the total ORAC value is divided by the weight of the composition in grams to give a pmol / g value. In any of the compositions described herein, the ORAC value for the composition is at least 1.5 times greater than the sum of the individual ORAC values for each component of the composition. In any of the compositions described herein, the ORAC value for the composition is at least 1.6 times greater than the sum of the individual ORAC values for each component of the composition. In any of the compositions described herein, the ORAC value for the composition is at least 1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.8, 1.9, 2.0, 2.1, 2.2, 2.3, 2.4, or 2.5 times greater than the sum of the individual ORAC values for each component of the composition. Goo In certain formulations, the compositions described herein have viscosity properties that stabilize the composition. In certain formulations, the composition is a high-viscosity gel that is stable during storage, retains its flavor over time, and allows minimal oxygen permeation. In certain formulations, the composition is thixotropic, having a high viscosity when stored and a lower viscosity when agitated, for example, by shaking or administration. In certain formulations, the composition is thixotropic and a high-viscosity gel that has good stability properties when stored and a lower viscosity when administered, allowing for easy administration and ingestion, favorable distribution in the gastrointestinal tract, and good absorption. In certain formulations, the composition has a viscosity of approximately 23 poise or more at a shear rate of 1 / second.In some forms, the composition has a viscosity of approximately 5 poise or less at a shear rate of 10 / second. In some forms, the composition has a viscosity of approximately 1 poise or less at a shear rate of 100 / second. In some forms, the composition has a viscosity of approximately 23 poise or more at a shear rate of 1 / second, a viscosity of approximately 5 poise or less at a shear rate of 10 / second, and a viscosity of approximately 1 poise or less at a shear rate of 100 / second. Methods The present description also relates to a method for reducing the number of oxygen free radicals in a mammal, which comprises administering to the mammal any of the compositions described herein. In certain embodiments, the oxygen free radicals to be reduced in number are selected from peroxyl radicals, hydroxyl radicals, peroxynitrite, superoxide anion, singlet oxygen, hypochlorite, and combinations thereof. In certain embodiments, the The MA / a / ZUZI 4Ó0Z method can reduce two, three, four, five, or six types of oxygen free radicals. In some modalities, the number of free oxygen radicals to be reduced is selected from peroxyl radicals, hydroxyl radicals, peroxynitrite, singlet oxygen of the superoxide anion, and hypochlorite in mammals. In some formulations, the synergistic effect observed with superoxide dismutase / soluble fiber combinations provides increased oxygen radical absorbance capacity (ORAC), which is beneficial for reducing inflammation. This description further relates to a method for reducing inflammation in a mammal, comprising administering to the mammal any of the compositions described herein. This description further relates to methods for treating a mammal of any disease or disorder associated with elevated levels of reactive oxygen species, comprising administering to the mammal any of the compositions described herein. In some formulations, the disease or disorder may be a bacterial infection; a viral infection; radiation sickness; a demyelinating disease, such as multiple sclerosis or neuropathy;a joint disorder, such as arthritis, rheumatoid arthritis, or psoriatic arthritis; a skin disorder, such as psoriasis, rosacea, acne vulgaris, dermatitis, or urticaria; a neurodegenerative disorder, such as multiple sclerosis, Parkinson's disease, amyotrophic lateral sclerosis, Alzheimer's disease, or Huntington's disease; a neuromuscular disease, such as muscular dystrophy or myasthenia gravis; tremors; bowel disorders, such as digestive inflammation, inflammatory bowel disease, Crohn's disease, colitis, diarrhea, leaky gut syndrome, diverticulitis, or celiac disease; asthma; inflammatory diseases, such as autoimmune disease, diabetes, gout, chronic prostatitis, glomerulonephritis, hidradenitis suppurativa, interstitial cystitis, lichen planus, mast cell activation syndrome, mastocytosis, otitis, or pelvic inflammatory disease; reperfusion injury; or chronic fatigue syndrome.rheumatic fever; rhinitis; sarcoidosis; transplant rejection and vasculitis. In some formulations, the synergistic effect observed with superoxide dismutase / soluble fiber combinations provides increased oxygen radical absorbance capacity (ORAC), which is beneficial for the prevention and treatment of viral infections. The formulations described herein can be used in methods for preventing viral infections, including influenza A, influenza B, influenza C, influenza D, coronaviruses including SARS (severe acute respiratory syndrome), SARS-CoV-2 (which causes COVID-19), MERS (Middle East respiratory syndrome), HIV, Ebola, rhinovirus, and respiratory syncytial virus.In terms of modality, the compositions described herein may be used in methods for treating viral infections, including influenza A, influenza B, influenza C, influenza D, coronaviruses including SARS (severe acute respiratory syndrome), SARS-CoV-2 (which causes COVID-19), MERS (Middle East respiratory syndrome), HIV, Ebola, rhinovirus, and respiratory syncytial virus. In some forms, the synergistic effect observed with superoxide dismutase / soluble fiber combinations provides a greater oxygen radical absorbance capacity (ORAC) that is beneficial for supplementing the diet of a patient undergoing cancer treatment. In some forms, the compositions described herein can be used in methods to supplement the diet of a mammal that is undergoing cancer treatment, has been exposed to radiation, or is suffering from malnutrition. In any of the methods described herein, the composition is administered to the mammal once a day. In any of the methods described herein, the composition is administered to the mammal twice a day. In any of the methods described herein, the composition is administered to the mammal three, four, five, six, seven, eight, nine, ten or more times a day. In some forms of any of the methods described herein, the mammal is a human. In other forms of any of the methods described herein, the mammal is a primate (e.g., monkey, ape, gorilla, macaque), a domestic animal (e.g., dog, cat, rabbit, hamster, guinea pig, mouse, rat), or a farm animal (e.g., cow, sheep, horse, goat, pig). EXAMPLES EXAMPLE 1: Example formulation An example formulation was prepared with the ingredient and concentrations shown in Table 2: Table 2 YES. # Ingredient Amount in mg 1 Soluble Corn Fiber (Fibersol-2) 4,000 2 Pomegranate Juice Concentrate 4,000 3 Concord Grape Juice Concentrate 4,000 4 Cranberry Juice Concentrate 2,000 5 Dark Sweet Cherry Juice Concentrate 1,450 6 Sour Cherry Juice Concentrate 1,450 7 Goji Pulp 294 8 Acai Juice Concentrate 200 9 Aloe Vera Juice 200 10 Green Tea 200 11 Resveratrol 80 12 Extramel SOD (14,000 units / g) 6 13 CMC 60.5 14 Xanthan 60.5 15 CS Water (30 mL) Ingredients 1-12 were combined into a homogeneous mixture using a stainless steel mixing tank. Before mixing, the ingredients were weighed according to the batch size. The juice concentrate was first thoroughly mixed in a separate tank, then the solid ingredients were pre-mixed with water in a separate mixer, and the two mixtures were combined in the main mixing tank. Sufficient water was added to reach the required volume, and the product was thoroughly mixed. The final product was pasteurized before being packaged in a bag. The formulation is a dark red gel. EXAMPLE 2: ORAC test of the example formulation Tests were conducted to determine the ORAC value of different components of the Example 1 formulation compared to the formulation as a whole. Samples of individual components were prepared using the sample weight in the total formulation: Sample A: 4 g of soluble corn fiber (Fibersol-2®); Sample B: 13.8749 g of fruit juice concentrate blend; and Sample O: 0.006 g of superoxide dismutase isolated from melon. Sample D was the finished product formulation, which weighed 31.1 g. The samples were sent to Brunswick Laboratories (Southborough, MA, USA) for analysis using the ORAC 6.0 test as described above and at https: / / brunswicklabs.com / capabilities / bioanalyticalservices / orac-family / orac6 / . The test results are provided in Table 3, with the results expressed as pmol equivalents of Trilox per gram of sample tested.The Conversion column provides a conversion of the normalized ORAC value for the sample amount. Table 3 Valar ORAC pmol TE / gram *TE = Trolox equivalence A. (Soluble corn fiber, Fibersol-2) 4 g B. (Fruit juice concentrate) 13.8749 g C. (SOD - Melon source) 0.006 g Final value A+B+C D. Finished product (30 mL W 31.1 g) Test Results Conversion Test Results Conversion Test Results Conversion Converted result Test Results Conversion Peroxyl radicals 1.50 6 128.04 1776.52 ND ND 1782.52 112.27 3,491.56 Hydroxyl radicals ND ND 648.11 8992.46 ND ND 8992.46 416.46 12,951.91 Peroxynitrite 0.24 0.96 34.46 478.13 ND ND 479.09 22.76 707.84 Superoxide anion ND ND 176.57 2449.89 ND ND 2449.89 134.2 4,173.62 Singlet oxygen ND ND 182.36 2516.36 ND ND 2516.36 109.20 3,396.12 Hypochlorite ND ND 926.85 12859.96 ND 0.10098 12860.07 749.22 23,300.74 Total 1.84 6.96 2,096.39 29,087.20 16.83 0.10098 29,094.26 1,544.61 48,021.79 As can be seen in Table 3, Sample D of the finished product shows an unexpectedly high and significantly higher ORAC value (48,021.79) compared to the total ORAC values of the individual component Samples (29,094.26). Therefore, the ORAC test suggests a synergistic effect among the components of the Example 1 formulation when these components are combined. Without intending to impose any theory, a possible contribution to this synergistic effect is a potential stabilizing effect that the other ingredients have on the superoxide dismutase enzyme, allowing superoxide dismutase to more effectively neutralize reactive oxygen species. EXAMPLE 3: Viscosity test of the example formulation The viscosity of the formulation from Example 1 was tested under various amounts of shear stress. A dynamic viscometer was used to test 5 mL of the formulation gel at a temperature of 25°C. The viscosity (at equilibrium) was tested for two separate samples of the formulation gel under increasing shear stress and shear rate over time, as shown in Tables 4 and 5. The normal stress at each time point is also shown. Table 4 - viscosity of gel formulation sample 1 (5 mL) under increasing shear stress. Shear stress Shear rate Viscosity Time Temperature Normal stress dynes / cm2 1 / sec poise sec °C dynes / cm2 9.156 0.09999 91.56 60.5 25 -5804 12.02 0.1585 75.81 125.53 25 -6041 14.58 0.2512 58.05 190.5 25 -6266 17.35 0.3981 43.57 255.53 25 -6536 20.42 0.631 32.36 320.52 25 -6686 23.85 1 23.85 385.5 25 -6706 27.66 1.585 17.45 450.55 25 -6558 32.03 2.512 12.75 515.58 25 -6370 37.1 3.981 9.32 580.52 25 -6290 43.19 6.31 6.845 645.53 25 -6199 50.68 10 5.068 710.53 25 -6252 60.15 15.85 3.7 95 775.53 2 5 -6420 71.93 25.12 2.863 840.52 25 -6842 87.02 39.81 2.186 905.53 25 -7154 106.8 63.1 1.693 970.52 25 -7429 133.1 100 1.331 1035.5 25 -7560 167.9 158.5 1.059 1100.5 25 -7728 213.8 251.2 0.851 1165.5 25 -7875 280.2 398.1 0.7039 1230.5 25 -8092 374.8 631 0.5941 1295.5 25 -8536 509 1000 0.509 1360.5 25 -9372 Table 5 - viscosity of gel formulation sample 2 (5 mL) under increasing shear stress. Shear stress Shear rate Viscosity Time Temperature Normal stress dynes / cm2 1 / sec poise sec °C dynes / cm2 9.444 0.1 94.42 60.984 25 -2232 13.28 0.1585 83.8 125.97 25 -2797 16.31 0.2512 64.92 190.92 25 -3238 18.74 0.3981 47.07 255.95 25 -3653 21.27 0.631 33.71 320.95 25 -4024 24.37 1 24.37 385.92 25 -4395 28.04 1.585 17.69 450.94 25 -4734 32.16 2.512 12.8 515.92 25 -5045 36.82 3.981 9.25 580.94 25 -5344 42.17 6.31 6.684 645.98 25 -5693 48.37 10 4 . 837 710.92 25 -5939 55.84 15.85 3.523 775.95 2 5 -6198 65.62 25.12 2.613 840.98 25 -6154 78.27 39.81 1.966 905.97 25 -6107 94.9 63.1 1.504 970.94 25 -6040 117 100 1.17 1036 25 -5768 147.5 158.5 0.9309 1101 25 -5671 188.4 251.2 0.7502 1166 25 -5826 249.1 398.1 0.6256 1231 25 -6237 330.8 631 0.5244 1295.9 25 -6803 445.3 1000 0.4453 1361 25 -7822 The values provided in Tables 4 and 5 are plotted in Figure 1. As can be seen in Tables 4 and 5 and in the Figure 1 shows that the gel formulation is surprisingly thixotropic, becoming less viscous after the application of shear stress. This thixotropic property can provide several advantages to the gel formulation. At rest, the gel formulation is a high-viscosity gel that helps the product maintain its physical composition, retain its flavor, and minimize oxygen permeation. During administration, agitation of the gel formulation causes it to become less viscous, and this resulting increase in fluidity facilitates oral administration while also promoting distribution of the formulation in the gastrointestinal tract, thus facilitating absorption. EXAMPLE 4: Improved recovery in patients with COVID-19 It was theorized that the superoxide dismutase and soluble fiber compositions described herein help strengthen the immune system, enabling a patient taking the composition to be more resistant to viral or bacterial infections and also better able to recover more quickly from such infections. The gel formulation of Example 1 was therefore administered to several patients who had tested positive for COVID-19, the disease caused by the SARS-CoV-2 virus. Current indications from researchers and medical professionals are that it can take up to two weeks to recover from COVID-19. All patients who received the gel formulation, regardless of age or sex, were able to recover faster than expected. Patient 1, a male between 41 and 50 years of age, tested positive for COVID-19 and was experiencing fever, cough, and loss of taste. He began taking the gel formulation twice daily five days after his positive test. Three to four days after starting the gel formulation, Patient 1 reported feeling much better, with less fatigue and more energy. Patient 2, a woman between 18 and 20 years old, tested positive for COVID-19 and was experiencing fever, cough, and headache. She began taking the gel formulation once a day on the day of her positive test. Three to four days after starting the gel formulation, Patient 2 reported feeling better, more energetic, and less fatigued. Patient 3, a man between 31 and 40 years old, tested positive for COVID-19 and was experiencing fever, cough, and headache while feeling very weak. He began taking the gel formulation once or twice a day four days after his positive test. Within two days of starting the gel formulation, Patient 3 reported feeling better, no longer feeling weak, and having more energy. Patient 4, a woman between 61 and 70 years old, tested positive for COVID-19 and was hospitalized with symptoms of fever, cough, headache, and loss of taste. She began taking the gel formulation once a day five days after her positive test. Within three or four days, she felt better with more energy and less fatigue. Patient 5, a man between 20 and 30 years old, tested positive for COVID-19 and was experiencing fever, cough, and headache. He began taking the gel formulation once a day three days after his positive test. Within two to four days, he felt better, more energetic, and less fatigued. EXAMPLE 5: Improvement of diabetes-related fatigue The patient was a middle-aged woman who had recently been diagnosed with diabetes. Even while following a careful diet, she suffered from overwhelming fatigue and had A1C levels as high as 10.2%. She began taking the gel formulation from Example 1, and by the end of the first day, she began to feel energized. After three days of taking the gel formulation, she reported having energy beyond her wildest dreams. EXAMPLE 6: Improvement of Myasthenia Gravis Symptoms The patient was a woman between 35 and 45 years of age who suffered from a rare form of muscular dystrophy called myasthenia gravis. The disease affected almost her entire muscular system, including breathing, walking, speech, swallowing, and eye movement. In July 2019, she was hospitalized for her condition and required the use of a wheelchair. She could not walk more than a few feet and struggled to breathe. She was prescribed a prednisone regimen for her symptoms with a daily dose of 40 mg. She began taking the gel formulation of Example 1 once daily along with a superoxide dismutase / soluble fiber powder formulation as described herein, also once daily. Three days later, she began to feel her symptoms improving and had more energy. After several months of taking this combination of gel and powder formulations, she now takes only 5 mg of prednisone daily, is able to be active, and walk long distances.And he no longer has trouble swallowing or speaking, and he no longer has trouble with eye movement. EXAMPLE 7: Improvement of multiple sclerosis symptoms The patient was a woman between 35 and 45 years old with multiple sclerosis. Her symptoms initially began in her legs but later progressed to her right arm. She frequently experienced pain, suffered from overwhelming fatigue, and had trouble sleeping. She began taking the gel formulation of Example 1 and soon was able to move her right arm with less pain. After taking the product for several months, she experienced significantly less pain and fatigue and slept better. She was able to reduce the amount of medication she was taking and increased her daily walking speed from about 3,500 steps to 11,000 steps. EXAMPLE 8: Improvement of gout symptoms The patient was a man between 40 and 50 years old who suffered from gout. He initially began taking the Example 1 gel formulation as a post-workout recovery supplement and noticed that after one month his symptoms improved. When his gout flared up, he took the Example 1 gel formulation twice a day, and his symptoms were under control after two days. EXAMPLE 9: Improved recovery from viral symptoms The patient was a woman experiencing viral symptoms, including shortness of breath and loss of taste. She was tested for COVID-19, but the result was negative. She took the gel formulation of Example 1 twice daily. After three days, she felt significantly better, and after five days, she was symptom-free. It will be readily apparent to someone experienced in the technique that other appropriate modifications and adaptations can be made to the methods and applications described herein without departing from the scope of any of the modalities. The preceding examples are included herein for illustrative purposes only and are not intended to be limiting. It should be understood that, although certain embodiments have been illustrated and described herein, the claims should not be limited to the specific forms or arrangements of the parts described and shown. The description includes illustrative embodiments, and although specific terms are used, they are used in a generic and descriptive sense only and not for the purpose of limitation. Modifications and variations of the embodiments are possible in light of prior teaching. Therefore, it should be understood that the embodiments may be implemented in ways other than those specifically described. Although several embodiments have been described above, it should be understood that they have been presented only as illustrations and examples of the present technology, and not as a limitation. It will be evident to those skilled in the relevant art that various changes in form and details can be made without departing from the spirit and scope of the present technology. Therefore, the breadth and scope of the present technology should not be limited by any of the embodiments described above, but should be defined solely in accordance with the appended claims and their equivalents. It is also understood that each feature of each embodiment described herein, and of each reference cited herein, may be used in combination with the features of any other embodiment. All patents and publications described herein are incorporated herein by reference. ML / a / ZUZ 1 4Ó0Z total. It is noted that with regard to this date, the method known to the applicant to carry out the aforementioned invention is the one that is clear from the description of the invention.
Claims
1. Composition, characterized in that it comprises from approximately 0.5 units / mg to approximately 500 units / mg of superoxide dismutase and a soluble fiber.
2. The composition according to claim 1, characterized in that it comprises from approximately 1 unit / mg to approximately 100 units / mg of superoxide dismutase.
3. The composition according to claim 1, characterized in that it comprises from approximately 5 units / mg to approximately 50 units / mg of superoxide dismutase.
4. The composition according to claim 1, characterized in that it comprises from approximately 10 units / mg to approximately 15 units / mg of superoxide dismutase.
5. The composition according to claim 1, characterized in that it comprises approximately 14 units / mg of superoxide dismutase.
6. The composition according to any of claims 1-5, characterized in that the superoxide dismutase is extracted from melon, bovine liver, heterotrophic bacteria, or marine phytoplankton.
7. The composition according to any of claims 1-6, characterized in that the superoxide dismutase is a copper / zinc superoxide dismutase, an iron / manganese superoxide dismutase or a nickel superoxide dismutase.
8. The composition according to any of claims 1-5, characterized in that the superoxide dismutase is extracted from a plant.
9. The composition according to claim 8, characterized in that the plant is a fruit, a grain or a tuber.
10. The composition according to claim 9, characterized in that the plant is a fruit selected from melon, citrus, peach, pear, apple or banana.
11. The composition according to claim 9, characterized in that the plant is a grain selected from wheat, barley, rye, millet, oats, spelt, bulgur, sorghum and farro.
12. The composition according to claim 9, characterized in that the plant is a tuber selected from horseradish, potato, yam, sweet potato, cassava or dahlia.
13. The composition according to any of claims 1-5, characterized in that the superoxide dismutase is extracted from an animal.
14. The composition according to claim 13, characterized in that the animal is a cow, a pig, a sheep or a goat.
15. The composition according to any of claims 1-5, characterized in that the superoxide dismutase is extracted from a microorganism.
16. The composition according to claim 15, characterized in that the microorganism is phytoplankton or bacteria.
17. The composition according to any of claims 1 to 16, characterized in that the ratio of superoxide dismutase to soluble fiber is approximately 1:100 to approximately 1:1,000 by weight.
18. The composition according to claim 17, characterized in that the ratio of superoxide dismutase to soluble fiber is approximately 1:200 to approximately 1:800 by weight.
19. The composition according to claim 17, characterized in that the ratio of superoxide dismutase to soluble fiber is approximately 1:300 to approximately 1:700 by weight.
20. The composition according to claim 17, characterized in that the ratio of superoxide dismutase to soluble fiber is approximately 1:500 to approximately 1:700 by weight.
21. The composition according to claim 17, characterized in that the ratio of superoxide dismutase to soluble fiber is approximately 1:650 to 1:675 by weight.
22. The composition according to any of claims 1-21, characterized in that the soluble fiber is a water-soluble polysaccharide.
23. The composition according to any of claims 1-21, characterized in that the soluble fiber is isolated from corn, wheat, barley, rye, beans, apples, pears, peaches, citrus fruits, berries, peas, rice bran or oats.
24. The composition according to any of claims 1-21, characterized in that the soluble fiber is selected from soluble maize fiber, inulin, dextrin, guar gum, oligopolysaccharides, galactopolysaccharides, fructooligosaccharides, lactulose, resistant starch, xylooligosaccharides and isomeltooligosaccharides.
25. The composition according to any of claims 1-21, characterized in that the soluble fiber is soluble corn fiber.
26. The composition according to claim 25, characterized in that the soluble corn fiber is digestion-resistant maltodextrin.
27. The composition according to any of claims 1-26, characterized in that it is in the form of a powder.
28. The composition according to claim 27, characterized in that it comprises from approximately 0.1 ppm to approximately 10 ppm of superoxide dismutase by weight.
29. The composition according to claim 27, characterized in that it comprises from approximately 0.5 ppm to approximately 5 ppm of superoxide dismutase by weight.
30. The composition according to claim 27, characterized in that it comprises from approximately 0.7 ppm to approximately 2 ppm of superoxide dismutase by weight.
31. The composition according to claim 27, characterized in that it comprises from approximately 0.8 ppm to approximately 1.2 ppm of superoxide dismutase by weight.
32. The composition according to any of claims 27-31, characterized in that it comprises from approximately 1% to approximately 90% by weight of soluble fiber.
33. The composition according to any of claims 27-31, characterized in that it comprises from approximately 1% to approximately 50% soluble fiber by weight.
34. The composition according to any of claims 27-31, characterized in that it comprises from approximately 5% to approximately 25% by weight of soluble fiber.
35. The composition according to any of claims 27-31, characterized in that it comprises approximately 10% to approximately 20% by weight of soluble fiber.
36. The composition according to any of claims 27-31, characterized in that it comprises approximately 12% to approximately 14% by weight of soluble fiber.
37. The composition according to any of claims 1-26, characterized in that it is in gel form.
38. The composition according to any of claims 1-26, characterized in that it is in liquid form.
39. The composition according to claim 37 or 38, characterized in that it comprises from approximately 0.005 mg / mL to approximately 3.0 mg / mL of superoxide dismutase.
40. The composition according to claim 37 or 38, characterized in that it comprises from approximately 0.01 mg / mL to approximately 2.0 mg / mL of superoxide dismutase.
41. The composition according to claim 37 or 38, characterized in that it comprises from approximately 0.05 mg / mL to approximately 1.0 mg / mL of superoxide dismutase.
42. The composition according to claim MA / a / ZUZI 4Ó0Z 37 or 38, characterized in that it comprises from approximately 0.1 mg / mL to approximately 0.5 mg / mL of superoxide dismutase.
43. The composition according to any of claims 37-42, characterized in that it comprises from approximately 50 mg / mL to approximately 1000 mg / mL of soluble fiber.
44. The composition according to any of claims 37-42, characterized in that it comprises from approximately 70 mg / mL to approximately 500 mg / mL of soluble fiber.
45. The composition according to any of claims 37-42, characterized in that it comprises from approximately 90 mg / mL to approximately 250 mg / mL of soluble fiber.
46. The composition according to any of claims 37-42, characterized in that it comprises from approximately 100 mg / mL to approximately 200 mg / mL of soluble fiber.
47. The composition according to any of claims 37-46, characterized in that it comprises a fruit juice.
48. The composition according to claim 47, characterized in that the fruit juice is pomegranate juice, red grape juice, cranberry juice, dark sweet cherry juice, sour cherry juice, goji berry juice, acal berry juice, blackberry juice, raspberry juice, strawberry juice, gooseberry juice, cranberry juice, orange juice, grapefruit juice, watermelon juice, beetroot juice, apple juice, lemon juice, lime juice, lychee juice, pineapple juice, prune juice or combinations thereof.
49. The composition according to claim 48, characterized in that the fruit juice is concentrated pomegranate juice, red grape juice, cranberry juice, dark sweet cherry juice, sour cherry juice, goji berry juice, acai berry juice, blackberry juice, raspberry juice, strawberry juice, currant juice, blueberry juice, orange juice, grapefruit juice, watermelon juice, beetroot juice, apple juice, lemon juice, lime juice, lychee juice, pineapple juice, prune juice, or combinations thereof.
50. The composition according to claim 49, characterized in that the concentrated fruit juice has from approximately 60% to approximately 97% of the water removed from the juice.
51. The composition according to claim 49, characterized in that the concentrated fruit juice has from approximately 85% to approximately 95% of the water removed from the juice.
52. The composition according to any of claims 49-51, characterized in that it comprises from approximately 5 mg / mL to approximately 200 mg / mL of concentrated fruit juice.
53. The composition according to any of claims 49-52, characterized in that it comprises from approximately 75 mg / mL to approximately 150 mg / mL of concentrated pomegranate juice.
54. The composition according to any of claims 49-53, characterized in that it comprises from approximately 75 mg / mL to approximately 150 mg / mL of concentrated red grape juice.
55. The composition according to any of claims 49-54, characterized in that it comprises from approximately 25 mg / mL to approximately 100 mg / mL of concentrated cranberry juice.
56. The composition according to any of claims 49-55, characterized in that it comprises from approximately 20 mg / mL to approximately 80 mg / mL of concentrated dark sweet cherry juice.
57. The composition according to any of claims 49-56, characterized in that it comprises from approximately 20 mg / mL to approximately 80 mg / mL of concentrated sour cherry juice.
58. The composition according to any of claims 49-57, characterized in that it comprises from approximately 2 mg / mL to approximately 20 mg / mL of concentrated goji berry juice.
59. The composition according to any of claims 49-58, characterized in that it comprises from approximately 2 mg / mL to approximately 20 mg / mL of concentrated acai berry juice.
60. The composition according to any of claims 37-59, characterized in that it further comprises aloe vera.
61. The composition according to claim 60, characterized in that the aloe vera is concentrated aloe vera.
62. The composition according to claim 61, characterized in that the concentrated aloe vera has from approximately 60% to approximately 97% of the water from the removed aloe vera.
63. The composition according to claim 61 or 62, characterized in that it comprises from approximately 2 mg / mL to approximately 20 mg / mL of concentrated aloe vera.
64. The composition according to any of claims 37-63, characterized in that it further comprises green tea.
65. The composition according to claim 64, characterized in that the green tea is concentrated green tea.
66. The composition according to claim 65, characterized in that the concentrated green tea is a green tea extract.
67. The composition according to claim 65 or 66, characterized in that it comprises from approximately 2 mg / mL to approximately 20 mg / mL of concentrated green tea.
68. The composition according to any of claims 37-67, characterized in that it further comprises resveratrol.
69. The composition of claim 68, characterized in that it comprises from approximately 0.5 mg / mL to approximately 6 mg / mL of resveratrol.
70. The composition according to any of claims 37 or 39-69, characterized in that it further comprises carboxymethylcellulose.
71. The composition according to claim 70, characterized in that it comprises from approximately 0.5 to approximately 5.0 mg / mL of carboxymethylcellulose.
72. The composition according to any of claims 37 or 39-71, characterized in that it further comprises xanthan gum.
73. The composition of claim 72, characterized in that it comprises from approximately 0.5 to approximately 5.0 mg / mL of xanthan gum.
74. Composition, characterized in that it comprises: a) from approximately 0.5 units / mg to approximately 100 units / mg of superoxide dismutase; b) a soluble fiber; and c) at least two fruit juices selected from pomegranate juice, red grape juice, cranberry juice, dark sweet cherry juice, sour cherry juice, goji berry juice and acal berry juice.
75. The composition according to claim 74, characterized in that it comprises at least three fruit juices.
76. The composition according to claim 74, characterized in that it comprises at least four fruit juices.
77. The composition according to claim 74, characterized in that it comprises at least five fruit juices.
78. The composition according to claim 74, characterized in that it comprises at least six fruit juices.
79. The composition according to claim 74, characterized in that it comprises pomegranate juice, red grape juice, cranberry juice, dark sweet cherry juice, sour cherry juice, goji berry juice, and acal berry juice.
80. The composition according to any of claims 74-79, characterized in that the fruit juices are concentrated fruit juices.
81. The composition according to any of claims 74 to 80, characterized in that the soluble fiber is soluble corn fiber.
82. The composition according to claim 81, characterized in that the soluble corn fiber is digestion-resistant maltodextrin.
83. Composition, characterized in that it comprises: a) superoxide dismutase; b) a soluble corn fiber; c) at least two fruit juices selected from pomegranate juice, red grape juice, cranberry juice, dark sweet cherry juice, sour cherry juice, goji berry juice and acai berry juice; d) aloe vera; e) green tea; and f) resveratrol.
84. The composition according to claim 83, characterized in that it comprises at least three fruit juices.
85. The composition according to claim 83, characterized in that it comprises at least four fruit juices.
86. The composition according to claim 83, characterized in that it comprises at least five fruit juices.
87. The composition according to claim 83, characterized in that it comprises at least six fruit juices.
88. The composition according to claim 83, characterized in that it comprises pomegranate juice, red grape juice, cranberry juice, dark sweet cherry juice, sour cherry juice, goji berry juice, and acai berry juice.
89. The composition according to any of claims 83-88, characterized in that the fruit juices are concentrated fruit juices.
90. The composition according to any of claims 83-89, characterized in that the soluble corn fiber is digestion-resistant maltodextrin.
91. The composition according to any of claims 83-90, characterized in that it further comprises carboxymethylcellulose.
92. The composition according to any of claims 83-91, characterized in that it further comprises xanthan gum.
93. Composition, characterized in that it comprises: a) from approximately 30 units to approximately 1,000 units of superoxide dismutase; b) from approximately 50 mg / mL to approximately 200 mg / mL of a soluble corn fiber; c) from approximately 5 mg / mL to approximately 200 mg / mL each of at least two concentrated fruit juices selected from pomegranate juice, red grape juice, cranberry juice, dark sweet cherry juice, sour cherry juice, goji berry juice and acai berry juice; d) from approximately 2 mg / mL to approximately 20 mg / mL of concentrated aloe vera; e) from approximately 2 mg / mL to approximately 20 mg / mL of concentrated green tea; and f) from approximately 0.5 mg / mL to approximately 6 mg / mL of resveratrol.
94. The composition of claim 93, characterized in that the soluble corn fiber is digestion-resistant maltodextrin.
95. The composition of claim 93 or 94, characterized in that it further comprises from approximately 0.5 to approximately 5.0 mg / mL of carboxymethylcellulose.
96. The composition according to any of claims 93-95, characterized in that it further comprises from approximately 0.5 to approximately 5.0 mg / mL of xanthan gum.
97. The composition according to any of claims 1-96, characterized in that it has an oxygen radical absorbance capacity (ORAC) greater than 1,000 pmol / g of the composition.
98. The composition according to any of claims 1-96, characterized in that it has an ORAC greater than 1500 pmol / g of the composition.
99. The composition according to any of claims 1-96, characterized in that an ORAC value for the composition is at least 1.5 times greater than the sum of the individual ORAC values for each component of the composition.
100. The composition according to any of claims 1-96, characterized in that an ORAC value for the composition is at least 1.6 times greater than the sum of the individual ORAC values for each component of the composition.
101. Method for reducing the number of oxygen free radicals in a mammal, characterized in that it comprises administering to the mammal a composition in accordance with any of claims 1-100.
102. The method according to claim 101, characterized in that the free oxygen radicals to be reduced in number are peroxyl radicals, hydroxyl radicals, peroxynitrite, superoxide anion, singlet oxygen, hypochlorite, or combinations thereof.
103. Method for reducing inflammation in a mammal, characterized in that it comprises administering to the mammal a composition in accordance with any of claims 1-100.
104. Method for reducing viral symptoms in a mammal, characterized in that it comprises administering to the mammal a composition in accordance with any of claims 1-100.
105. The method according to any of claims 101-104, characterized in that the composition is administered to the mammal once a day.
106. The method of any one of claims 101-104, characterized in that the composition is administered to the mammal twice a day.
107. The method according to any of claims 101-105, characterized in that the mammal is a human.