Method for improving ginsenoside content of panax ginseng containing silver colloid solvent, and panax ginseng composition having increased ginsenoside content

Abstract

The present invention relates to: a method for improving the ginsenoside content of panax ginseng containing a silver colloid solvent; and a panax ginseng composition having an increased ginsenoside content. Using the method of the present invention has the effect of making it possible to increase the ginsenoside content by fertilizing just two times at a low concentration of 10 ppm at harvesttime without having to fertilize consistently for 6 years.

Description

Method for improving ginsenoside content of ginseng (PANAX GINSENG) containing silver colloidal solvent and ginseng composition with increased ginsenoside content

[0001] The present invention relates to a method for improving the ginsenoside content of ginseng including a silver colloidal solvent and a ginseng composition having increased ginsenoside content.

[0002] Ginseng (Panax ginseng) is a perennial shade-loving herbaceous plant belonging to the genus Panax in the family Araliaceae. It has long been used as an important medicinal ingredient in oriental medicine. Ginseng is generally classified as white ginseng and red ginseng depending on the processing method. White ginseng is raw ginseng dug up from the field and dried as is, while red ginseng is fresh ginseng that is steamed and dried. During the manufacturing process, various chemical changes such as saponin modification, amino acid change, and browning occur. Since ginseng contains saponin, it can be expected to have excellent pharmacological effects such as cancer prevention, inhibition of cancer cell growth, lowering blood pressure, protection of brain nerve cells, and improvement of learning ability.

[0003] Ginseng saponins are called ginsenosides, which are glycosides isolated from ginseng to distinguish them from other plant saponins. They are usually named ginsenoside-Rx, etc. (abbreviated as G-Rx). Here, "R" means Radix or Root. In addition, "x" is named in order from bottom to top according to the migration distance (Rf value) of the spot that appears on the TLC, such as o, a, b, c, d, e, f, g, h. The types of ginsenosides currently known to be contained in ginseng include Rg1, Rb1, Rg2, Rc, and Rd.

[0004] Korean Patent No. 10-0464901 discloses a bactericidal trace element fertilizer containing silver colloid particles, Korean Patent Publication No. 2016-0086149 discloses a composition containing a ginseng extract with increased ginsenoside content as an active ingredient, and Korean Patent No. 10-1603169 discloses a method for producing a ginseng extract with increased acidic polysaccharide and ginsenoside content. However, no method of using a silver colloid solvent to increase the content of ginsenoside according to the present invention has been disclosed.

[0005] Regarding the effects of Ag-NP (silver nano-particle) fertilization on plants, antibacterial action against soil pathogenic bacteria, plant growth promotion, and plant secondary metabolism enhancement effects have been reported in some plants, and the possibility of using silver colloidal solvents in agriculture has been reported, but there are not many examples of application methods.

[0006] The present invention aims to provide a method of utilizing a silver colloidal solvent to improve the ginseng ginsenoside content by analyzing the effect of applying a silver colloidal solvent having a different composition to ginseng on the growth and differentiation of ginseng and analyzing the change in the ginsenoside content in ginseng roots.

[0007] (Patent Document 0001) Republic of Korea Patent No. 10-0464901

[0008] (Patent Document 0002) Republic of Korea Publication Patent No. 2016-0086149

[0009] (Patent Document 0003) Republic of Korea Patent No. 10-1603169

[0010] The present invention provides a method for improving the ginsenoside content of ginseng including a silver colloid solvent and a ginseng composition with increased ginsenoside content.

[0011] The present invention provides a method for improving the ginsenoside content of ginseng comprising a silver colloidal solvent.

[0012] In addition, the present invention provides a ginseng composition having an increased ginsenoside content by the above method.

[0013] When the method of the present invention is used, it is effective in increasing the ginsenoside content with only two fertilizations at a low concentration of 10 ppm at the harvest time without having to fertilize consistently for six years.

[0014] Figure 1 shows the results of ginseng growth-differentiation analysis according to one embodiment of the present invention (Experimental Example 1), and shows the results of measuring the diameter of each ginseng crown when the silver colloid solvents of Examples 1 to 5 were applied.

[0015] Figure 2 shows the results of ginseng growth-differentiation analysis according to one embodiment of the present invention (Experimental Example 1), and shows the results of measuring the length of each ginseng stem when the silver colloid solvents of Examples 1 to 5 were applied.

[0016] Figure 3 shows the results of ginseng growth-differentiation analysis according to one embodiment of the present invention (Experimental Example 1), and shows the results of measuring the length of each ginseng leaf when the silver colloid solvents of Examples 1 to 5 were applied.

[0017] Figure 4 shows the results of ginseng growth-differentiation analysis according to one embodiment of the present invention (Experimental Example 1), and shows the results of measuring the width of each ginseng leaf when the silver colloid solvents of Examples 1 to 5 were applied.

[0018] Figure 5 shows the results of ginseng growth-differentiation analysis according to one embodiment of the present invention (Experimental Example 1), and shows the results of measuring the number of ginseng leaves in each case where the silver colloid solvents of Examples 1 to 5 were applied.

[0019] Figure 6 shows the results of ginseng growth-differentiation analysis according to one embodiment of the present invention (Experimental Example 1), showing the results of measuring the diameter of each ginseng root when the silver colloidal solvents of Examples 1 to 5 were applied.

[0020] Figure 7 shows the results of ginseng growth-differentiation analysis according to one embodiment of the present invention (Experimental Example 1), and shows the results of measuring the length of each ginseng root when the silver colloid solvents of Examples 1 to 5 were applied.

[0021] Figure 8 shows the results of ginseng ginsenoside analysis according to one embodiment of the present invention (Experimental Example 2), showing 10 major ginsenosides in the V1 treatment group and unknown substances A to N that increased compared to the control group.

[0022] Figure 9 shows the results of ginseng ginsenoside analysis according to one embodiment of the present invention (Experimental Example 2), showing 10 major ginsenosides in the En treatment group and unknown substances A to N that increased compared to the control group.

[0023] Figure 10 shows the results of ginseng ginsenoside analysis according to one embodiment of the present invention (Experimental Example 2), showing 10 major ginsenosides in the Zx treatment group and unknown substances A to N that increased compared to the control group.

[0024] Figure 11 shows the results of analyzing 10 types of ginsenosides in ginseng roots treated with silver colloid solvent according to Examples 1 to 3 of the present invention.

[0025] Figure 12 shows the results of comparative analysis of protopanaxatriol (PPT) series ginsenosides in ginseng roots treated with silver colloid solvents according to Examples 1 to 3 of the present invention.

[0026] Figure 13 shows the results of comparative analysis of protopanaxadiol (PPD) series ginsenosides in ginseng roots treated with silver colloid solvents according to Examples 1 to 3 of the present invention.

[0027] Figure 14 shows the total contents of 10 kinds of ginsenosides in ginseng roots treated with silver colloid solvents of Examples 1 to 3 of the present invention.

[0028] Hereinafter, embodiments of the present invention will be described in detail so that those skilled in the art can easily implement the invention. These embodiments of the present invention are provided to more fully explain the invention to those of ordinary skill in the art. Therefore, the embodiments of the present invention may be modified in various ways, and the scope of the present invention is not limited to the embodiments described below.

[0029] Throughout the specification of the present invention, when a part is said to "include" a certain component, this does not mean that other components are excluded, but rather that other components may be included, unless specifically stated otherwise.

[0030] One embodiment of the present invention provides a method for improving the ginsenoside content of ginseng, comprising a silver colloidal solvent.

[0031] The above silver colloidal solvent may be composed solely of silver colloid, but is not limited thereto.

[0032] The above silver colloid concentration may be 500 to 5,000 ppm, specifically 1,000 to 4,500 ppm, 1,500 to 4,500 ppm, 1,500 to 4,000 ppm, 2,000 to 4,000 ppm, more specifically 2,100 to 3,900 ppm, 2,200 to 3,800 ppm, 2,300 to 3,700 ppm, 2,400 to 3,600 ppm, 2,500 to 3,500 ppm, 2,600 to 3,400 ppm, 2,700 to 3,300 ppm, 2,800 to 3,200 ppm, 2,900 to 3,100 ppm, 3000 ppm. However, it is not limited to these.

[0033] In addition, the silver colloid solvent of the present invention may include silver colloid and a major component of a fertilizer. The major components of the fertilizer may be, but are not limited to, N, P, and K. Specifically, the major components may be at least one selected from the group consisting of nitrogen, phosphorus, potassium, manganese, boron, molybdenum, zinc, and copper. The components may be water-soluble, but are not limited thereto.

[0034] The nitrogen may be 1 to 10 wt% based on the total solvent weight. Specifically, it may be 2 to 10 wt%, 3 to 10 wt%, 4 to 10 wt%, 5 to 10 wt%, 5 to 9 wt%, 5 to 8 wt%, more specifically, 5.5 to 8 wt%, 6 to 8 wt%, 6.5 to 8 wt%, 7 to 8 wt%, and even more specifically, 7.1 to 7.9 wt%, 7.2 to 7.8 wt%, 7.3 to 7.7 wt%, 7.4 to 7.6 wt%, 7.5 wt%, but is not limited thereto.

[0035] The phosphoric acid may be present in an amount of 0.5 to 5 wt% based on the total solvent weight. Specifically, it may be present in an amount of 0.5 to 4.5 wt%, 0.5 to 4 wt%, 0.5 to 3.5 wt%, 0.5 to 3 wt%, 0.5 to 2.5 wt%, 0.5 to 2 wt%, and more specifically, it may be present in an amount of 0.6 to 1.9 wt%, 0.7 to 1.8 wt%, 0.8 to 1.7 wt%, 0.9 to 1.6 wt%, 1 to 1.5 wt%, 1.1 to 1.4 wt%, 1.1 to 1.3 wt%, or 1.2 wt%, but is not limited thereto.

[0036] The above potassium may be 1 to 5 wt% based on the total solvent weight. Specifically, it may be 1 to 4.5 wt%, 1 to 4 wt%, 1 to 3.5 wt%, 1 to 3 wt%, 1.5 to 3 wt%, more specifically, 1.6 to 3 wt%, 1.7 to 3 wt%, 1.8 to 3 wt%, 1.9 to 3 wt%, 2 to 3 wt%, 2.1 to 2.9 wt%, 2.2 to 2.8 wt%, 2.3 to 2.6 wt%, 2.5 wt%, but is not limited thereto.

[0037] The manganese may be present in an amount of 0.01 to 1 wt% based on the total solvent weight. Specifically, 0.01 to 0.9 wt%, 0.01 to 0.8 wt%, 0.01 to 0.7 wt%, 0.01 to 0.6 wt%, 0.01 to 0.5 wt%, 0.01 to 0.4 wt%, 0.01 to 0.3 wt%, 0.01 to 0.2 wt%, more specifically, 0.02 to 0.2 wt%, 0.03 to 0.2 wt%, 0.04 to 0.2 wt%, 0.05 to 0.2 wt%, 0.06 to 0.2 wt%, 0.07 to 0.2 wt%, 0.08 to 0.2 wt%, 0.09 to 0.2 wt%, 0.1 to 0.2 wt%, 0.11 to 0.19 wt%, It may be 0.12 to 0.18 wt%, 0.13 to 0.17 wt%, 0.14 to 0.16 wt%, or 0.15 wt%, but is not limited thereto.

[0038] The boron may be present in an amount of 0.001 to 1 wt% based on the total solvent weight. Specifically, the boron may be present in an amount of 0.001 to 0.5 wt%, 0.005 to 0.5 wt%, 0.01 to 0.5 wt%, 0.01 to 0.4 wt%, 0.01 to 0.3 wt%, 0.01 to 0.2 wt%, 0.01 to 0.1 wt%, and more specifically, 0.02 to 0.1 wt%, 0.03 to 0.1 wt%, 0.04 to 0.1 wt%, 0.05 to 0.1 wt%, 0.06 to 0.1 wt%, 0.07 to 0.1 wt%, 0.07 to 0.09 wt%, or 0.08 wt%, but is not limited thereto.

[0039] The above molybdenum may be 0.001 to 1 wt% based on the total solvent weight. Specifically, 0.001 to 0.5 wt%, 0.001 to 0.4 wt%, 0.001 to 0.3 wt%, 0.001 to 0.2 wt%, 0.001 to 0.1 wt%, more specifically, 0.001 to 0.09 wt%, 0.002 to 0.09 wt%, 0.003 to 0.09 wt%, 0.004 to 0.09 wt%, 0.005 to 0.09 wt%, 0.006 to 0.09 wt%, 0.007 to 0.09 wt%, 0.008 to 0.09 wt%, 0.009 to 0.09 wt%, 0.01 to 0.09 wt%, and even more specifically, 0.01 to 0.08 wt%, It may be 0.01 to 0.07 wt%, 0.01 to 0.06 wt%, 0.01 to 0.05 wt%, 0.01 to 0.04 wt%, 0.01 to 0.03 wt%, 0.01 to 0.02 wt%, or 0.01 wt%, but is not limited thereto.

[0040] The above zinc may be 0.01 to 1 wt% based on the total solvent weight. Specifically, it may be 0.01 to 0.9 wt%, 0.01 to 0.8 wt%, 0.01 to 0.7 wt%, 0.01 to 0.6 wt%, 0.01 to 0.5 wt%, 0.02 to 0.5 wt%, 0.03 to 0.5 wt%, 0.04 to 0.5 wt%, 0.05 to 0.5 wt%, 0.06 to 0.5 wt%, 0.07 to 0.5 wt%, 0.08 to 0.5 wt%, 0.09 to 0.5 wt%, 0.1 to 0.5 wt%, more specifically, 0.1 to 0.4 wt%, 0.1 to 0.3 wt%, 0.15 to 0.25 wt%, 0.2 wt%, but is not limited thereto.

[0041] The above copper may be 0.01 to 1 wt% based on the total solvent weight. Specifically, 0.01 to 0.9 wt%, 0.01 to 0.8 wt%, 0.01 to 0.7 wt%, 0.01 to 0.6 wt%, 0.01 to 0.5 wt%, 0.01 to 0.4 wt%, 0.01 to 0.3 wt%, 0.01 to 0.2 wt%, more specifically, 0.01 to 0.19 wt%, 0.02 to 0.18 wt%, 0.03 to 0.17 wt%, 0.04 to 0.16 wt%, 0.05 to 0.15 wt%, 0.06 to 0.14 wt%, 0.07 to 0.13 wt%, 0.08 to 0.12 wt%, 0.09 to 0.11 wt%, 0.1 wt% However, it is not limited to this.

[0042] In addition, the silver colloid solvent of the present invention may include a silver colloid and a silver particle stabilizer. The silver particle stabilizer may be at least one selected from the group consisting of, but not limited to, carbonic acid, anionic phosphorus-containing surfactants, anionic polymers, and nitrogen-containing polymers.

[0043] The concentration of the silver particle stabilizer may be 1,000 to 50,000 ppm. Specifically, 1,000 to 40,000 ppm, 1,000 to 30,000 ppm, 1,000 to 20,000 ppm, 2,000 to 20,000 ppm, 3,000 to 20,000 ppm, 4,000 to 20,000 ppm, 5,000 to 20,000 ppm, 6,000 to 20,000 ppm, 7,000 to 20,000 ppm, 8,000 to 20,000 ppm, 9,000 to 20,000 ppm, 10,000 to 20,000 ppm, more specifically, 11,000 to 20,000 ppm, 12,000 to 20,000 ppm, 13,000 to 20,000 ppm, 14,000 to 20,000 ppm, 15,000 to 20,000 ppm, 15,000 to 19,000 ppm, 15,000 to 18,000 ppm, 15,000 to 17,000 ppm, 15,500 to 16,500 ppm, 16,000 ppm, but is not limited thereto.

[0044] In addition, one embodiment of the present invention provides a ginseng composition having an increased ginsenoside content by the above method.

[0045] Hereinafter, the present invention will be described in more detail through examples and experimental examples. However, the following examples and experimental examples are intended to aid understanding of the present invention and are not intended to limit the scope of the present invention.

[0046] <Example 1> Preparation of colloidal solvent Zeroxxe

[0047] In order to analyze the effects of the composition of silver colloidal solvent on ginseng crop growth and the content of ginseng ginsenosides, a silver colloidal solvent containing only silver colloid at a concentration of 3,000 ppm was prepared and named Zeroxxe.

[0048] <Example 2> Preparation of Eunbi, a colloidal solvent

[0049] In order to analyze the effect of the composition of silver colloidal solvent on ginseng crop growth and the content of ginseng ginsenosides, a silver colloidal solvent containing N, P, and K, which are the main components of silver colloid and fertilizer, was prepared and named Eunbi.

[0050] Specifically, 7.5% nitrogen, 1.2% water-soluble phosphoric acid, 2.5% water-soluble potassium, 0.15% water-soluble manganese, 0.08% water-soluble boron, 0.01% water-soluble molybdenum, 0.2% water-soluble zinc, and 0.1% water-soluble copper were added to silver colloid at a concentration of 2,200 ppm.

[0051] <Example 3> Preparation of colloidal solvent Variant 1 (silver grass 1)

[0052] In order to analyze the effect of the composition of silver colloidal solvent on ginseng crop growth and the content of ginseng ginsenosides, a silver colloidal solvent containing silver colloid and carbonic acid, a silver particle stabilizer, was prepared and named Variant 1 (Eunjandi 1).

[0053] Specifically, 16,000 ppm of carbonic acid was added to 4,000 ppm of silver colloid.

[0054] <Example 4> Preparation of silver colloidal solvent Variant 2 (silver grass 2)

[0055] In order to analyze the effect of the composition of silver colloidal solvent on ginseng crop growth and ginseng ginsenoside content, a silver colloidal solvent containing silver colloid and an anionic phosphorus-containing surfactant as a silver particle stabilizer was prepared and named Variant 2 (Eunjandi 2).

[0056] Specifically, an anionic phosphorus-containing surfactant at a concentration of 16,000 ppm was added to silver colloid at a concentration of 4,000 ppm.

[0057] <Example 5> Preparation of silver colloidal solvent Variant 3 (silver grass 3)

[0058] In order to analyze the effect of the composition of silver colloidal solvent on ginseng crop growth and the content of ginseng ginsenosides, a silver colloidal solvent containing silver colloid and an anionic high molecular, nitrogen-containing polymer as a silver particle stabilizer was prepared and named Variant 3 (Eunjandi 3).

[0059] Specifically, an anionic polymer, a nitrogen-containing polymer, was added at a concentration of 8,000 ppm to a silver colloid at a concentration of 2,000 ppm.

[0060] Table 1 shows the components of the silver colloid products / prototypes of Examples 1 to 5.

[0061] Product / Prototype Colloidal Concentration (ppm) Characteristics Example 1 Zeroxxe 3,000- Example 2 Eunbi 2,200 Nitrogen 7.5%, Soluble Phosphoric Acid 1.2%, Soluble Potassium 2.5%, Soluble Manganese 0.15%, Soluble Boron 0.08%, Soluble Molybdenum 0.01%, Soluble Zinc 0.2%, Soluble Copper 0.1%, Example 3 Variant 14,000 Stabilizer: 16,000 ppm of the modified carbonic acid Example 4 Variant 24,000 Stabilizer: 16,000 ppm of an anionic phosphorus-containing surfactant Example 5 Variant 32,000 Stabilizer: 8,000 ppm of an anionic high molecular, nitrogen-containing polymer

[0062] <Experimental Example 1> Growth-differentiation analysis

[0063] In order to investigate the effects of silver colloidal solvents Zeroxxe (Zx), Eunbi (En), Variant 1 (Silver Grass 1), Variant 2 (Silver Grass 2), and Variant 3 (Silver Grass 3) manufactured in Examples 1 to 5, 6-year-old ginseng plants grown in the open field were evenly fertilized twice at one-week intervals at a concentration of 10 ppm, and then growth information regarding crown diameter, stem length, leaf length, leaf width, number of leaves, root diameter, and root length was investigated.

[0064] Figures 1 to 7 show the results of comparative analysis of growth information of 6-year-old phosphoric acid plants according to treatment with silver colloid products manufactured in Examples 1 to 5.

[0065] As a result, the leaf tissue growth of 6-year-old ginseng was not significantly affected by the two-time application of 'silver' colloidal solvent (10 ppm) of Examples 1 to 5, but it was confirmed that there was a slight difference in the diameter and length of ginseng roots, but the difference was not statistically significant. However, it was found that the root length significantly increased in Example 1 (Zeroxxe (Zx)), Example 2 (Eunbi (En)), and Example 3 (Variant 1 (Eunjandi 1)).

[0066] <Experimental Example 2> Analysis of ginseng ginsenosides

[0067] After comparing and analyzing ginseng growth information, differences were observed in the length and diameter of ginseng roots. After treatment for 18 hours in a 10 ppm concentration solution of three types of silver colloids (En, Zx, V1), ginsenoside metabolism analysis was performed.

[0068] Specifically, among the 'silver' colloidal solvents of Examples 1 to 5, Example 1 (Zeroxxe (Zx)), Example 2 (Eunbi (En)), and Example 3 (Variant 1 (Eunjandi 1)) that showed differences in root length were selected, and quantitative analysis was conducted on a total of 10 well-known ginsenoside substances, including 5 substances (Rb1, Rb2, Rb3, Rc, Rd) from the protopanaxadiol (PPD; eg, Ra, Rb, Rc, Rd, Rg3, Rh2) series and 5 substances (Re, Rf, Rg1, Rg2, Rh) from the protopanaxatriol (PPT; eg, Re, Rf, Rg1, Rg2, Rh1) series.

[0069] Ginseng root samples treated with liquid nitrogen were finely ground and extracted and purified by adding 10 ml of 50% MeOH per 1 g. After extraction, the samples were analyzed using a high-performance liquid chromatography (HPLC) Agilent 110 series, Waters Symmetry C18 column at a flow rate of 1 ml / min under gradient conditions using a UV detector (203 nm).

[0070] Figure 8 shows the 10 major ginsenosides in the V1 treatment group and unknown substances A to N that increased compared to the control group, Figure 9 shows the 10 major ginsenosides in the En treatment group and unknown substances A to N that increased compared to the control group, and Figure 10 shows the 10 major ginsenosides in the Zx treatment group and unknown substances A to N that increased compared to the control group.

[0071] As a result of analyzing 10 major ginsenosides in the roots of 3-year-old ginseng grown in open fields treated with silver colloid in Examples 1 to 3, unknown metabolites that were different from the control group in addition to the 10 major ginsenosides were identified in the chromatogram results for the analysis of ginsenosides in the roots of 3-year-old ginseng treated with silver colloid in Examples 1 to 3.

[0072] Among the identified unknown metabolites (A to N), the substance corresponding to D was identified only in the Zx treatment and not in En and V1, and all A to N substances except D were found to be enhanced in the silver colloid treatment group.

[0073] Figure 11 shows the results of analyzing 10 types of ginsenosides in silver colloid-treated ginseng roots of Examples 1 to 3, Figure 12 shows the results of comparative analysis of protopanaxatriol (PPT) series ginsenosides, and Figure 13 shows the results of comparative analysis of protopanaxadiol (PPD) series ginsenosides.

[0074] As a result of the analysis, it was confirmed that Re, Rg1, Rf, Rb1, Rg2, Rh1, and Rc increased significantly (p<0.001) in the V1 treatment group, and that Rb2 and Rd increased in content at the P<0.05 level.

[0075] Within the En treatment group, Rg1, Rf, and Rc were significantly increased (P<0.001), and Rb1 and Rh1 were significantly increased (P<0.01). Re and Rg2 were significantly decreased (P<0.001).

[0076] Within the Zx treatment group, Rg1, Rf, Rb1, Rg2, Rh1, Rc, Rb2, and Rd were significantly increased (P<0.001), and Rb3 content increased at a level of P<0.01. Re content was confirmed to decrease at a level of P<0.01.

[0077] As shown in Figure 14, the total content of 10 types of ginsenoside was in the order of Zx > V1 > En, and since En was not statistically significant, it was finally confirmed that Zx and V1 treatment had a significant effect on promoting ginsenoside metabolism in ginseng roots.

[0078] In conclusion, it was confirmed that the presence or absence of fertilizer components (N, P, K) in silver colloidal solvent (10 ppm) and the presence or absence of silver particle stabilizer did not significantly affect the aerial growth of ginseng, but there was a slight difference in root growth.

[0079] In addition, the presence or absence of fertilizer components (N, P, K) in silver colloid solvent (10 ppm) did not significantly affect the increase in the total content of ginsenosides in ginseng root tissues, but the Rf, Rg1, and Rb1 substances were confirmed to be increased, and there was no significant difference between the conditions with or without stabilizers, confirming the efficacy of increasing the content of all 10 types of ginsenosides by silver grass (prototype) and Zeroxxe fertilization.

[0080]

[0081] According to the method using the silver colloid solvent of the present invention, it was confirmed that it is possible to increase the ginsenoside content with only two fertilizations at a low concentration of 10 ppm at the harvest time without having to fertilize consistently for six years.

Claims

1. A method for improving the ginsenoside content of ginseng (Panax ginseng), comprising a colloidal solvent.

2. A method for improving the ginsenoside content of ginseng, wherein the silver colloidal solvent further contains a main component of a fertilizer.

3. A method for improving the ginsenoside content of ginseng, wherein the main component of the fertilizer in paragraph 2 is at least one selected from the group consisting of nitrogen, phosphorus, potassium, manganese, boron, molybdenum, zinc, and copper.

4. A method for improving the ginsenoside content of ginseng, wherein the silver colloid solvent further contains a silver particle stabilizer in the first paragraph.

5. A method for improving the ginsenoside content of ginseng, wherein the silver particle stabilizer in paragraph 4 is at least one selected from the group consisting of carbonic acid, anionic phosphorus-containing surfactants, anionic polymers, and nitrogen-containing polymers.

6. A method for improving the ginsenoside content of ginseng, wherein the method improves the growth and development of ginseng according to any one of paragraphs 1 to 5.

7. A ginseng composition having increased ginsenoside content by the method of any one of claims 1 to 5.

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