Electrode plate, tumor-treating field system, temperature detection method, and signal application method

Abstract

The present application provides an electrode plate, a tumor-treating field system, a temperature detection method, and a signal application method. The electrode plate comprises a plurality of electrode units and a flexible circuit board used for accommodating the plurality of electrode units arranged at intervals and embedded with a plurality of paths of conductive traces electrically connected to the electrode units. The plurality of electrode units are divided into a plurality of row groups and a plurality of column groups. The plurality of paths of conductive traces comprise a plurality of paths of grounding wires that are in one-to-one correspondence with the plurality of row groups of the electrode units and a plurality of paths of dual-purpose signal lines that are in one-to-one correspondence with the plurality of column groups of the electrode units. Each path of grounding signal line is configured to short-circuit and ground each electrode unit in the corresponding row group. Each path of dual-purpose signal line is configured to not only transmit an alternating current signal to each electrode unit in the corresponding column group, but also transmit a direct current signal to each electrode unit in the corresponding column group or transmit a detected temperature detection signal of each electrode unit in the corresponding column group.

Description

Electrode sheet, tumor electric field therapy system, temperature detection method, and signal application method Technical Field

[0001] The present application relates to Tumor Treating Fields (TTF) technology, and in particular to an electrode sheet, a tumor treating field system, a temperature detection method, and a signal application method. Background Art

[0002] Tumor electric field therapy is a method that uses low-intensity, medium- and high-frequency alternating electric fields to prevent the formation of spindle microtubules during mitosis in certain tumor cells, inhibit the separation of intracellular organelles during cell division, and induce apoptosis in mitotic cells, thereby achieving the effect of treating tumors.

[0003] Compared with traditional cancer treatments, TTF has an innovative mechanism of action. Some physiological characteristics of tumor cells, such as geometric shape and high-frequency mitosis, make them susceptible to TTF. TTF disrupts the normal aggregation of tubulin by exerting directional forces on polar particles (such as macromolecules and organelles) in cells. These processes may lead to physical damage to the cell membrane and cell apoptosis. At the end of cell mitosis, the structural morphology of the cleavage furrow will lead to uneven distribution of the electric field around it. At the same time, under the influence of TTF, the electric field intensity at the cleavage furrow is significantly enhanced, and the charged substances in the cell move toward the cleavage furrow, which interferes with or even destroys the formation of the cell structure, and ultimately leads to cell division failure and apoptosis.

[0004] In existing tumor therapy field systems, an electric field applicator transmits the alternating current (AC) signal for tumor therapy to electrodes, which then apply an alternating electric field to the patient's tumor site. When the tumor therapy field is applied to the patient's body, heat accumulates at the application site, causing the temperature to rise accordingly. Therefore, the temperature at the application site must be monitored. If the temperature is too high, the electric field intensity must be adjusted promptly to reduce the risk of skin burns caused by excessive heat.

[0005] The tumor electric field therapy system includes at least one pair of electrode sheets, each of which contains multiple electrode units. Even if the same alternating current signal is applied to each electrode unit, the heat generated by each electrode unit will be different due to its different position, that is, the temperature of each electrode unit on the entire electrode sheet will not be completely consistent. In this way, it is possible that the temperature of some electrode units in the entire electrode sheet exceeds the preset temperature, while the temperature of other electrode units is normal. In order to improve the effect of tumor electric field therapy, it is necessary to implement individual control of the overheated electrode units. However, for existing electrode sheets, implementing individual control of the electrode units requires providing a conductive trace for each electrode unit in the substrate of the electrode sheet. This will increase the number of conductive traces in the electrode sheet substrate, making the electrode sheet less likely to bend, and the cable electrically connected to the electrode sheet will also be thickened, which increases the overall weight of the electrode sheet, making it difficult to apply the electrode sheet.

[0006] Therefore, it is necessary to provide an electrode sheet, a tumor electric field therapy system, a temperature detection method, and a signal application method that use fewer conductive traces to perform partitioned control on multiple electrode units.

[0007] Summary of the Invention

[0008] One purpose of the present application is to provide an electrode sheet for tumor electric field therapy to solve or eliminate the problems in the related art.

[0009] The second object of the present invention is to provide a tumor electric field therapy system.

[0010] The third object of the present invention is to provide a method for detecting the temperature of an electrode sheet.

[0011] A fourth object of the present invention is to provide a method for detecting the quality of an electrode sheet.

[0012] A fifth object of the present invention is to provide a method for detecting electrode replacement.

[0013] A sixth object of the present invention is to provide a method for detecting abnormal temperature of an electrode sheet.

[0014] A seventh object of the present invention is to provide a method for controlling the application of alternating electric signals for tumor electric field therapy.

[0015] The eighth object of the present invention is to provide a signal control method for tumor electric field therapy.

[0016] A ninth object of the present invention is to provide a method for identifying electrode sheet types.

[0017] A tenth object of the present invention is to provide a computer-readable storage medium.

[0018] The eleventh object of the present invention is to provide an adapter for tumor electric field therapy.

[0019] The twelfth object of the present invention is to provide an electric field generator for tumor electric field therapy.

[0020] To achieve the above-mentioned objectives, the present invention provides an electrode sheet for tumor electric field therapy, which includes a plurality of electrode units, wherein the plurality of electrode units are divided into a plurality of row groups and a plurality of column groups; and a flexible circuit board, configured for the plurality of electrode units to be arranged at intervals thereon, and having multiple conductive traces embedded therein, the multiple conductive traces including: a plurality of grounding wires, corresponding one-to-one to the plurality of row groups, each of the grounding wires being configured to short-circuit each electrode unit in the corresponding row group to ground; and a plurality of dual-purpose signal lines, corresponding one-to-one to the plurality of column groups, each of the dual-purpose signal lines being configured to transmit both an alternating current signal to each electrode unit in the corresponding column group and a direct current signal or a temperature detection signal detected by each electrode unit in the corresponding column group.

[0021] According to the electrode sheet of the embodiment of the present invention, a plurality of electrode units are divided into a plurality of row groups and a plurality of column groups, and each electrode unit in each row group is short-circuited through the same ground wire, and each electrode unit in each column group is used to transmit both AC signals and DC signals or collect temperature detection signals of each electrode unit through the same dual-purpose signal line. In this way, a 100% temperature detection coverage rate of the electrode units can be achieved without increasing the conductive traces of the electrode sheet, thereby avoiding excessive weight on the electrode sheet and maintaining the application effect of the electrode sheet. In addition, the wiring design of the flexible circuit board of the electrode sheet is reduced, the manufacturing process is simplified, and the manufacturing cost is reduced.

[0022] Furthermore, the number of the dual-purpose signal lines is related to the number of the column groups into which the electrode units are divided, and the number of the ground lines is related to the number of the row groups into which the electrode units are divided.

[0023] Furthermore, the number of the dual-purpose signal lines is not less than the number of the column groups into which the electrode units are divided.

[0024] Furthermore, the number of the dual-purpose signal lines is equal to the number of column groups into which the electrode units are divided.

[0025] Furthermore, the number of the grounding lines is not less than the number of the row groups into which the electrode units are divided.

[0026] Furthermore, the number of the connection wires is equal to the number of the row groups into which the electrode units are divided.

[0027] Furthermore, the total number of the conductive traces is equal to the sum of the number of the row groups and the number of the column groups into which the electrode units are divided.

[0028] Furthermore, each of the electrode units includes a dielectric element for transmitting an alternating current signal and a temperature sensor having a signal terminal and a ground terminal, and the temperature sensor is used to detect the temperature of the corresponding electrode unit.

[0029] Furthermore, the dielectric element of each electrode unit is short-circuited with the signal end of the temperature sensor.

[0030] Furthermore, each of the electrode units further includes a diode connected in series with the temperature sensor, and the temperature sensor is grounded via the diode connected in series with the temperature sensor.

[0031] Furthermore, the dielectric elements of the plurality of electrode units in the same column group are connected in parallel to the same dual-purpose signal line of the flexible circuit board, the dielectric elements of the plurality of electrode units in different column groups are connected in parallel through different dual-purpose signal lines of the flexible circuit board, the dielectric elements of the plurality of electrode units in the same row group are connected in parallel through different dual-purpose signal lines of the flexible circuit board, and the dielectric elements of the plurality of electrode units in different row groups and different column groups are connected in parallel to different dual-purpose signal lines of the flexible circuit board.

[0032] Furthermore, the dielectric elements of the plurality of electrode units in the same column group are connected in parallel with the signal ends of the respective temperature sensors through the same dual-purpose signal line of the flexible circuit board, and the dielectric elements of the plurality of electrode units in different column groups are connected in parallel with the signal ends of the respective temperature sensors through different dual-purpose signal lines of the flexible circuit board.

[0033] Furthermore, the ground ends of the temperature sensors of the multiple electrode units located in the same row group are short-circuited through the same ground line of the flexible circuit board, and the ground ends of the temperature sensors of the multiple electrode units located in the same column group are connected in parallel through different ground lines of the flexible circuit board; the signal ends of the temperature sensors of the multiple electrode units located in the same row group are connected in parallel through different dual-purpose signal lines of the flexible circuit board, and the signal ends of the temperature sensors of the multiple electrode units located in the same column group are short-circuited through the same dual-purpose signal line of the flexible circuit board.

[0034] Furthermore, the dielectric elements of the plurality of electrode units located in the same row group are respectively connected in parallel through different dual-purpose signal lines of the flexible circuit board, and the dielectric elements of the plurality of electrode units located in the same column group are all short-circuited through the same dual-purpose signal line of the flexible circuit board.

[0035] Furthermore, the total number of the electrode units does not exceed 20.

[0036] Furthermore, the total number of the electrode units is 20, which are divided into 4 row groups, and the number of the electrode units in each row group is 5; or divided into 5 column groups, and the number of the electrode units in each column group is 4.

[0037] Furthermore, the flexible circuit board is embedded with 5 dual-purpose signal lines and 4 ground lines.

[0038] Furthermore, when the electrode unit performs temperature detection, only one of the multiple grounding lines is turned on at the same time, and the other multiple grounding lines are disconnected. When the electrode unit performs temperature detection, all the multiple dual-purpose signal lines are turned on.

[0039] Furthermore, the plurality of dual-purpose signal lines are all or partially turned on when the electrode unit applies an AC signal, and the plurality of ground lines are all turned off when the electrode unit applies an AC signal.

[0040] Furthermore, it also includes a first cable electrically connected to the flexible circuit board.

[0041] Furthermore, the first cable has 9 core conductors, and each core conductor is electrically connected to the multi-channel dual-purpose signal wire and the multi-channel ground wire embedded in the flexible circuit board in a one-to-one correspondence.

[0042] To achieve the above objectives, the present invention also provides a tumor electric field therapy system, which includes the aforementioned electrode sheet.

[0043] Furthermore, it also includes: an electric field generator, configured to provide an alternating current signal to multiple electrode units of the electrode sheet via the dual-purpose signal line of the electrode sheet; and an adapter, connected between the electrode sheet and the electric field generator, configured to transmit the alternating current signal generated by the electric field generator to the multiplexed dual-purpose signal line of the electrode sheet, and also configured to receive the temperature detection signal output by the multiplexed dual-purpose signal line of the electrode sheet.

[0044] Furthermore, the adapter includes: an AC signal line configured to provide an alternating current signal to each of the electrode units in the corresponding column group through the multiple dual-purpose signal lines.

[0045] Furthermore, the adapter also includes: multiple groups of grounding switches, each group of grounding switches is electrically connected to a corresponding electrode sheet and includes multiple grounding switches, and the multiple grounding switches are respectively electrically connected to the multiple grounding lines of the corresponding electrode sheet and are configured to control the conduction or disconnection of the multiple grounding lines.

[0046] Furthermore, the adapter also includes: multiple groups of analog-to-digital converters, which are respectively electrically connected to the multiplexed signal lines of the corresponding electrode sheets, and are configured to receive the temperature detection signals transmitted by the multiplexed signal lines of the corresponding electrode sheets and convert the temperature detection signals from analog signals to digital signals, wherein each group of analog-to-digital converters includes multiple detection channels, and each detection channel is used to connect to a corresponding one of the multiplexed signal lines.

[0047] Furthermore, the adapter also includes: multiple groups of bidirectional switches, corresponding one-to-one to the multiple electrode sheets, each group of bidirectional switches includes multiple bidirectional switches, and the multiple bidirectional switches are electrically connected one-to-one to the multi-channel dual-purpose signal lines of the corresponding electrode sheets; wherein each of the bidirectional switches also has a signal acquisition terminal 1 electrically connected to a corresponding detection channel in the corresponding analog-to-digital converter and a signal input terminal 2 electrically connected to the AC signal line.

[0048] Furthermore, the adapter also includes: a first controller, which is respectively connected to the multiple groups of grounding switches and the multiple groups of bidirectional switching switches, and is configured to: control the opening and closing states of the multiple grounding switches in sequence and cycle, and then sequentially and individually conduct each grounding line of the multiple grounding lines of the corresponding electrode sheets; and control the switching states of the multiple bidirectional switching switches, so that the bidirectional switching switches are placed at the signal acquisition end 1 to output the temperature detection signal, or the bidirectional switching switches are placed at the signal input end 2 to transmit the AC signal.

[0049] Furthermore, the adapter further includes: a first communication unit configured to obtain digital signals output by the multiple groups of analog-to-digital converters and send the digital signals to the electric field generator.

[0050] Furthermore, the electric field generator is further configured to control or adjust the alternating current signal provided to the corresponding electrode unit among the plurality of electrode units of the corresponding electrode sheet according to the received digital signal.

[0051] Furthermore, the first communication unit is controlled by the first controller and serially transmits the digital signal converted by the analog-to-digital converter.

[0052] Furthermore, it also includes: a second cable, wherein the second cable is configured to connect the adapter and the electric field generator.

[0053] To achieve the above-mentioned purpose, the present invention also provides an electrode sheet temperature detection method, which is applied to the above-mentioned electrode sheet or to the above-mentioned tumor electric field therapy system, and the method includes the following steps: turning on all the multiplexed signal lines corresponding one-to-one to the multiple column groups of the corresponding electrode sheet; and turning on each of the multiple grounding lines corresponding one-to-one to the multiple row groups of the electrode sheet in sequence and in a time-sharing manner to collect the temperature detection signals of each electrode unit in each row group of the electrode sheet by row through the multiplexed signal lines.

[0054] To achieve the above-mentioned purpose, the present invention further provides an electrode sheet qualification detection method, wherein whether the electrode sheet is qualified is judged based on the temperature detection signal of each electrode unit of the electrode sheet obtained by the above-mentioned electrode sheet temperature detection method.

[0055] Furthermore, the determination of whether the electrode sheet is qualified includes the following steps: determining whether each electrode unit has an abnormality or a fault based on the temperature detection signal of each electrode unit of the electrode sheet; and determining whether the electrode sheet is qualified based on whether each electrode unit has an abnormality or a fault.

[0056] Furthermore, whether the electrode sheet is qualified is judged as follows: when all the electrode units of the electrode sheet have no abnormality or no fault, the electrode sheet is judged to be qualified; or when one of the electrode units of the electrode sheet has an abnormality or a fault, the electrode sheet is judged to be unqualified.

[0057] To achieve the above object, the present invention also provides an electrode sheet replacement detection method, wherein whether the electrode sheet needs to be replaced is determined based on the temperature detection signal of each electrode unit of the electrode sheet obtained by the above electrode sheet temperature detection method.

[0058] Furthermore, whether the electrode sheet needs to be replaced is determined by the following steps: determining whether each electrode unit has an abnormality or a fault based on the temperature detection signal obtained from each electrode unit; and determining whether the electrode sheet needs to be replaced based on whether each electrode unit has an abnormality or a fault.

[0059] Furthermore, the method of judging whether the electrode sheet needs to be replaced based on whether each electrode unit has an abnormality or a fault includes the following steps: determining the number of electrode units with abnormalities or faults; judging whether the number of electrode units with abnormalities or faults exceeds a preset threshold; and determining whether the electrode sheet needs to be replaced based on the judgment result.

[0060] Furthermore, the judgment result includes that the number of the electrode units with abnormalities or faults does not exceed a preset threshold and the number of the electrode units with abnormalities or faults exceeds a preset threshold. Whether the electrode sheet needs to be replaced is judged as follows: when the number of the electrode units with abnormalities or faults does not exceed the preset threshold, it is judged that the electrode sheet does not need to be replaced; or when the number of the electrode units with abnormalities or faults exceeds the preset threshold, it is judged that the electrode sheet needs to be replaced.

[0061] Furthermore, the preset threshold is 20% of the total number of all electrode units of the electrode sheet.

[0062] To achieve the above-mentioned purpose, the present invention also provides a method for detecting abnormal temperature of an electrode sheet, wherein the abnormal temperature of the electrode sheet is determined to be qualified according to the above-mentioned electrode sheet qualified detection method, and the temperature detection signal of each electrode unit of the electrode sheet is obtained according to the above-mentioned electrode sheet temperature detection method.

[0063] Furthermore, the determination of abnormal temperature of the electrode sheet includes the following steps: comparing the obtained temperature of each electrode unit with a preset temperature threshold; and determining whether the temperature of the electrode sheet is abnormal based on the comparison result.

[0064] Furthermore, the comparison result includes not exceeding the preset temperature threshold and exceeding the preset temperature threshold. Whether the temperature of the electrode sheet is abnormal is judged as follows: when the temperature of one of the electrode units exceeds the preset temperature threshold, it is determined that the electrode sheet has a temperature abnormality; or when the temperatures of all electrode units do not exceed the preset temperature threshold, it is determined that the electrode sheet does not have a temperature abnormality.

[0065] Furthermore, the preset temperature threshold is 40.5°C-41.5°C.

[0066] Furthermore, the preset temperature threshold is 41°C-41.5°C.

[0067] Furthermore, the preset temperature threshold is 41°C.

[0068] To achieve the above objectives, the present invention also provides a method for controlling the application of an alternating current signal for tumor electric field therapy, which is applied to the above electrode sheet or the above tumor electric field therapy system.

[0069] Furthermore, the AC signal applied to each electrode unit of the electrode sheet is controlled or adjusted based on the temperature detection signal of each electrode unit of the electrode sheet obtained by the above-mentioned electrode sheet temperature detection method when the above-mentioned electrode sheet replacement detection method determines that the electrode sheet does not need to be replaced.

[0070] Furthermore, the controlling or adjusting the AC signal applied to each electrode unit of the electrode sheet includes: comparing the obtained temperature of each electrode unit with a preset temperature threshold; and controlling or adjusting the AC signal applied according to the comparison result.

[0071] Furthermore, the control or adjustment of the alternating current signal applied to each electrode unit of the electrode sheet according to the comparison result is completed in the following manner: when the temperature detection signals of each electrode unit of the electrode sheet obtained do not exceed the preset temperature threshold, the alternating current signal continues to be applied to each electrode unit of the electrode sheet; or when there is a temperature detection signal among the temperature detection signals of each electrode unit of the electrode sheet obtained that exceeds the preset temperature threshold, the application of the alternating current signal to the electrode unit of the electrode sheet is stopped.

[0072] Furthermore, stopping applying AC signals to the electrode units of the electrode sheet includes stopping applying AC signals to all electrode units of the electrode sheet, stopping applying AC signals to electrode units in the electrode sheet whose temperature detection signals exceed a preset temperature threshold, and stopping applying AC signals to all electrode units in the column where the electrode units in the electrode sheet whose temperature detection signals exceed a preset temperature threshold are located.

[0073] Furthermore, when the application of the AC signal to the electrode unit in the electrode sheet whose temperature detection signal exceeds the preset temperature threshold is stopped, the AC signal continues to be applied to the electrode unit in the electrode sheet whose temperature detection signal does not exceed the preset temperature threshold.

[0074] Furthermore, when the application of the alternating current signal to all electrode units in the column where the electrode unit whose temperature detection signal in the electrode sheet exceeds the preset temperature threshold is located is stopped, the alternating current signal continues to be applied to all electrode units in the electrode sheet where the temperature detection signal does not exceed the preset temperature threshold and is in a different column from the electrode unit whose temperature detection signal exceeds the preset temperature threshold.

[0075] Furthermore, the comparison result includes not exceeding a preset temperature threshold and exceeding a preset temperature threshold, and not exceeding the preset temperature threshold includes being far below the preset temperature threshold and being close to the preset temperature threshold.

[0076] Furthermore, when the temperature detection signals of the electrode sheet do not exceed the preset temperature threshold, the alternating current signal is continued to be applied to the electrode units of the electrode sheet in the following manner: when the temperature detection signal is far below the preset temperature threshold, the alternating current signal is continued to be applied to the electrode units of the electrode sheet in a manner of increasing the voltage or current amplitude of the alternating current signal currently applied to the electrode units of the electrode sheet, or the alternating current signal is continued to be applied to the electrode units of the electrode sheet in a manner of keeping the voltage or current amplitude of the alternating current signal currently applied to the electrode units of the electrode sheet unchanged; or when the temperature detection signal is close to the preset temperature threshold, the alternating current signal is continued to be applied to the electrode units of the electrode sheet in a manner of keeping the voltage or current amplitude of the alternating current signal currently applied to the electrode units of the electrode sheet unchanged, or the alternating current signal is continued to be applied to the electrode units of the electrode sheet in a manner of reducing the voltage or current amplitude of the alternating current signal currently applied to the electrode units of the electrode sheet.

[0077] Furthermore, the preset temperature threshold is 40.5°C-41.5°C.

[0078] Furthermore, the preset temperature threshold is 41°C-41.5°C.

[0079] Furthermore, the preset temperature threshold is 41°C.

[0080] To achieve the above-mentioned object, the present invention also provides a signal control method for tumor electric field therapy, which is applied to the above-mentioned electrode sheet or to the above-mentioned tumor electric field therapy system.

[0081] Furthermore, the signal for tumor electric field therapy is achieved by combining and controlling the conduction and disconnection of multiple dual-purpose signal lines that correspond one-to-one to each column group of the electrode sheet and are electrically connected to the electrode units of each column group, and multiple ground lines that correspond one-to-one to each row group of the electrode sheet and are electrically connected to the electrode units of each row group, and by using the multiple dual-purpose signal lines electrically connected to each electrode unit of the electrode sheet to enable each electrode unit of the electrode sheet to cyclically switch between applying an alternating current signal and collecting or transmitting a temperature detection signal.

[0082] Furthermore, the process of applying an AC signal to each electrode unit of the electrode sheet includes the following steps: disconnecting the multiple grounding lines that are electrically connected one-to-one to the electrode units of each row group of the electrode sheet, and at the same time, connecting the multiple dual-purpose signal lines that are electrically connected one-to-one to the electrode units of each column group of the electrode sheet so that the multiple dual-purpose signal lines electrically connected to the electrode sheet transmit the AC signal to each electrode unit.

[0083] Furthermore, the process of enabling each electrode unit of the electrode sheet to transmit a temperature detection signal includes the following steps: turning on the multiple dual-purpose signal lines electrically connected one by one to the electrode units of each column group of the electrode sheet so that the multiple dual-purpose signal lines electrically connected to the electrode sheet transmit a DC signal to each electrode unit; and sequentially turning on one ground line of the multiple ground lines electrically connected one by one to the electrode units of each row group of the electrode sheet so as to complete the transmission of the temperature detection signal of each electrode unit in each row group of the electrode sheet row by row through the multiple dual-purpose signal lines electrically connected to the electrode sheet.

[0084] Furthermore, the steps are also included: determining a combined control method for turning on or off the multiple ground lines corresponding to each row group of the electrode sheet and the multiple dual-purpose signal lines corresponding to each column group of the electrode sheet based on the temperature detection signals obtained from each electrode unit; and controlling the working state of each electrode unit of the electrode sheet based on the determined combined control method for turning on or off the multiple ground lines and the multiple dual-purpose signal lines.

[0085] Furthermore, the working state of each electrode unit of the electrode sheet includes one of stopping applying the alternating current signal and continuing to collect the temperature detection signal and stopping collecting the temperature detection signal and continuing to apply the alternating current signal.

[0086] Furthermore, the continued application of the AC signal includes one of the following: continuing to apply the AC signal in a manner of increasing the voltage or current amplitude of the currently applied AC signal, continuing to apply the AC signal in a manner of keeping the voltage or current amplitude of the currently applied AC signal unchanged, and continuing to apply the AC signal in a manner of reducing the voltage or current amplitude of the currently applied AC signal.

[0087] To achieve the above-mentioned object, the present invention further provides an electrode sheet type identification method, which is applied to the above-mentioned electrode sheet or to the above-mentioned tumor electric field therapy system.

[0088] Furthermore, the type of the electrode sheet is identified based on the temperature detection signal of each electrode unit of the electrode sheet obtained by the above-mentioned electrode sheet temperature detection method when the electrode sheet is determined to be qualified according to the above-mentioned electrode sheet qualification detection method.

[0089] In order to achieve the above-mentioned purpose, the present invention also provides a computer-readable storage medium, on which an electrode sheet temperature detection program is stored, and when the electrode sheet temperature detection program is executed by the controller, the above-mentioned electrode sheet temperature detection method is implemented; or an electrode sheet qualification detection program is stored on the medium, and when the electrode sheet qualification detection program is executed by the controller, the above-mentioned electrode sheet qualification detection method is implemented; or an electrode sheet replacement detection program is stored on the medium, and when the electrode sheet replacement detection program is executed by the controller, the above-mentioned electrode sheet replacement detection method is implemented; or an electrode sheet temperature anomaly detection program is stored on the medium, and when the electrode sheet temperature anomaly detection program is executed by the controller, the above-mentioned electrode sheet temperature anomaly detection method is implemented. When executed, the above-mentioned electrode sheet temperature abnormality detection method is realized; or an AC signal application control program for tumor electric field therapy is stored thereon, and when the AC signal application control program for tumor electric field therapy is executed by the controller, the above-mentioned AC signal application control method for tumor electric field therapy is realized; or a signal control program for tumor electric field therapy is stored thereon, and when the signal control program for tumor electric field therapy is executed by the controller, the above-mentioned signal control method for tumor electric field therapy is realized; or an electrode sheet type identification program is stored thereon, and when the electrode sheet type identification program is executed by the controller, the above-mentioned electrode sheet type identification method is realized.

[0090] To achieve the above objectives, the present invention further provides an adapter for tumor electric field therapy, comprising a memory and a controller, and further comprising:

[0091] An electrode sheet temperature detection program stored in a memory and executable on a controller, wherein when the controller executes the electrode sheet temperature detection program, the above-mentioned electrode sheet temperature detection method is implemented; or

[0092] An electrode sheet qualification detection program stored in a memory and executable on a controller, wherein when the controller executes the electrode sheet qualification detection program, the above-mentioned electrode sheet qualification detection method is implemented; or

[0093] An electrode sheet replacement detection program stored in a memory and executable on a controller, wherein when the controller executes the electrode sheet replacement detection program, the above-mentioned electrode sheet replacement detection method is implemented; or

[0094] An electrode sheet temperature anomaly detection program stored in a memory and executable on a controller, wherein when the controller executes the electrode sheet temperature anomaly detection program, the above-mentioned electrode sheet temperature anomaly detection method is implemented; or

[0095] An AC signal application control program for tumor therapeutic field therapy stored in a memory and executable on a controller, wherein when the controller executes the AC signal application control program for tumor therapeutic field therapy, the AC signal application control method for tumor therapeutic field therapy described above is implemented; or

[0096] A tumor therapy field signal control program stored in a memory and executable on a controller, wherein when the controller executes the tumor therapy field signal control program, the aforementioned tumor therapy field signal control method is implemented; or

[0097] An electrode sheet type identification program is stored in the memory and can be run on the controller. When the controller executes the electrode sheet type identification program, the above-mentioned electrode sheet type identification method is implemented.

[0098] To achieve the above objectives, the present invention further provides an electric field generator for tumor electric field therapy, which includes a memory and a controller, and further includes:

[0099] An electrode sheet temperature detection program stored in a memory and executable on a controller, wherein when the controller executes the electrode sheet temperature detection program, the above-mentioned electrode sheet temperature detection method is implemented; or

[0100] An electrode sheet qualification detection program stored in a memory and executable on a controller, wherein when the controller executes the electrode sheet qualification detection program, the above-mentioned electrode sheet qualification detection method is implemented; or

[0101] An electrode sheet replacement detection program stored in a memory and executable on a controller, wherein when the controller executes the electrode sheet replacement detection program, the above-mentioned electrode sheet replacement detection method is implemented; or

[0102] An electrode sheet temperature anomaly detection program stored in a memory and executable on a controller, wherein when the controller executes the electrode sheet temperature anomaly detection program, the above-mentioned electrode sheet temperature anomaly detection method is implemented; or

[0103] An AC signal application control program for tumor therapeutic field therapy stored in a memory and executable on a controller, wherein when the controller executes the AC signal application control program for tumor therapeutic field therapy, the AC signal application control method for tumor therapeutic field therapy described above is implemented; or

[0104] A tumor therapy field signal control program stored in a memory and executable on a controller, wherein when the controller executes the tumor therapy field signal control program, the aforementioned tumor therapy field signal control method is implemented; or

[0105] An electrode sheet type identification program is stored in the memory and can be run on the controller. When the controller executes the electrode sheet type identification program, the above-mentioned electrode sheet type identification method is implemented.

[0106] The above description is only an overview of the technical solution of the present application. In order to more clearly understand the technical means of the present application, it can be implemented in accordance with the contents of the specification. In order to make the above and other purposes, features and advantages of the present application more obvious and easy to understand, the specific implementation methods of the present application are listed below. BRIEF DESCRIPTION OF THE DRAWINGS

[0107] FIG1 is a schematic diagram of a tumor treating field system according to an embodiment of the present application;

[0108] FIG2 is a schematic diagram of the structure of the electrode sheet of the tumor electric field treatment system shown in FIG1;

[0109] FIG3 is a schematic diagram of the circuit connection between an electrode sheet and an adapter of the tumor electric field system shown in FIG1 ;

[0110] FIG4 is similar to FIG3 , which is another circuit connection diagram of an electrode sheet and an adapter shown in FIG3 ;

[0111] FIG5 is a schematic diagram of the circuit connection between an electrode sheet, an adapter, and an electric field generator of the tumor electric field system shown in FIG1;

[0112] FIG6 is a schematic block diagram of the internal structure of the adapter of the tumor therapeutic field system shown in FIG1 ;

[0113] FIG7 is a schematic block diagram of the internal structure of the electric field generator of the tumor treating field system shown in FIG1 ;

[0114] FIG8 is a flow chart of a temperature detection method for a tumor treating field system according to an embodiment of the present application;

[0115] FIG9 is a schematic flow chart of a method for detecting electrode sheet quality according to an embodiment of the present application;

[0116] FIG10 is a schematic flow chart of an electrode sheet replacement detection method according to an embodiment of the present application;

[0117] FIG11 is a flow chart of a method for detecting abnormal electrode temperature according to an embodiment of the present application;

[0118] FIG12 is a flow chart of a method for controlling application of an alternating current signal for tumor therapeutic field therapy according to an embodiment of the present application;

[0119] FIG13 is a schematic flow chart of an electrode type identification method according to an embodiment of the present application;

[0120] FIG14 is a flow chart of a signal control method for tumor therapeutic field therapy according to an embodiment of the present application;

[0121] FIG15 is a flow chart of a method for detecting electrode temperature according to another embodiment of the present application;

[0122] FIG16 is a flow chart of a method for applying an alternating current signal for tumor treating field therapy according to another embodiment of the present application;

[0123] FIG17 is a flow chart of a method for applying an AC signal based on a temperature detection signal according to an embodiment of the present application;

[0124] FIG18 is a flow chart of a method for applying an alternating current signal based on a temperature detection signal according to another embodiment of the present application.

[0125] Explanation of the accompanying drawings: Tumor electric field therapy system 100, electrode sheet 13, first cable 15, adapter 20, second cable 25, electric field generator 30, flexible circuit board 31, electrode unit 33, temperature sensor 34, ground terminal 34-1, signal terminal 34-2, dielectric element 35, diode 36, second power supply module 32, second controller 37, second communication unit 38, AC signal generator 39, AC signal switch 40, first controller 51, analog-to-digital converter 52, voltage divider resistor 53, ground switch 54, first ground switch 54-1, second ground switch 54-2, third ground switch 54-3, fourth ground switch 54-4, bidirectional switch 55, first bidirectional switch 55-1, second bidirectional switch 55-2, third bidirectional switch 55-3 , fourth bidirectional switch 55-4, fifth bidirectional switch 55-5, first communication unit 56, AC signal line 57, first power module 58, grounding line 18, first grounding line 18-1, second grounding line 18-2, third grounding line 18-3, fourth grounding line 18-4, dual-purpose signal line 19, first dual-purpose signal line 19-1, second dual-purpose signal line 19-2, third dual-purpose signal line 19-3, fourth dual-purpose signal line 19-4, fifth dual-purpose signal line 19-5, first connector 60, first plug 61, first socket 62, second connector 70, second plug 71, second socket 72. DETAILED DESCRIPTION

[0126] The following embodiments of the technical solution of the present application will be described in detail with reference to the accompanying drawings. The following embodiments are only used to more clearly illustrate the technical solution of the present application and are therefore only examples and are not intended to limit the scope of protection of the present application.

[0127] Figure 1 is a schematic diagram of a tumor electric field therapy system 100 according to the present invention. As shown in Figure 1 , the tumor electric field therapy system 100 includes at least one pair of electrode sheets 13, an adapter 20 connected to the electrode sheets 13, and an electric field generator 30 connected to the adapter 20. The electric field generator 30 supplies power to the electrode sheets 13, causing them to generate a therapeutic electric field. The adapter 20 is electrically connected between the electrode sheets 13 and the electric field generator 30 and is used to transmit the alternating current (AC) signal generated by the electric field generator 30 to the electrode sheets 13. In other words, the electric field generator 30 generates an AC signal, which is transmitted to each electrode sheet 13 via the adapter 20, generating a therapeutic electric field for treating tumors between the same pair of electrode sheets 13. As shown in Figure 1 , in this embodiment, there are four electrode sheets 13. Each electrode sheet 13 includes a plurality of electrode units 33, each of which is electrically connected to the adapter 20. There are 20 electrode units 33 on each electrode sheet 13. In other embodiments, the tumor electric field treatment system 100 may also have more or fewer electrode sheets 13. In other embodiments, each pair of electrode sheets 13 has the same number of electrode units 33, and different pairs of electrode sheets 13 may have different numbers of electrode units 33.

[0128] Figures 3 and 4 are schematic diagrams of the circuit connection between the electrode sheet 13 and the adapter 20 in two working states of the tumor electric field therapy system 100. It is worth noting that the arrangement of the electrode units 33 shown in Figures 3 and 4 is to more clearly illustrate the electrical connection between an electrode sheet 13 and the adapter 20. The arrangement of the electrode units 33 shown in Figures 3 and 4 does not represent the arrangement of the electrode units 33 in the spatial structure. In combination with Figures 1, 3 and 4, the electrode sheet 13 includes: a flexible circuit board 31, a plurality of electrode units 33 electrically connected to the flexible circuit board 31 at intervals, and a first cable 15 electrically connected to the flexible circuit board 31. The flexible circuit board 31 is embedded with multiple conductive traces (18, 19), and the multiple conductive traces (18, 19) include multiple ground lines 18 and multiple dual-purpose signal lines 19. The first cable 15 includes multiple conductors (not shown), each of which is electrically connected to the multiple grounding wires 18 and multiple dual-purpose signal wires 19 of the flexible printed circuit board 31. The total number of grounding wires 18 and dual-purpose signal wires 19 embedded in the flexible printed circuit board 31 does not exceed 10. Therefore, the number of conductors in the first cable 15 does not exceed 10.

[0129] In this embodiment, each electrode sheet 13 is provided with 20 electrode units 33. The 20 electrode units 33 are arranged in the order of 1 to 20 for circuit connection, divided into four row groups and five column groups. That is, the 20 electrode units 33 are arranged in four rows and five columns for circuit connection. Each electrode unit 33 includes a dielectric element 35 and a temperature sensor 34. The temperature sensor 34 includes a ground terminal 34-1 and a signal terminal 34-2. The dielectric element 35 and the temperature sensor 34 are both soldered to the flexible circuit board 31, with the dielectric element 35 short-circuited to the signal terminal 34-2 of the corresponding temperature sensor 34. Because the multiple temperature sensors 34 are provided in a one-to-one correspondence with the multiple electrode units 33, the multiple temperature sensors 34 are also arranged in four rows and five columns for circuit connection. It should be noted that the arrangement here is to more clearly illustrate the electrical connection between the electrode sheet 13 and the adapter 20, and does not represent the arrangement of the electrode unit 33 in the spatial structure. Its spatial structure may be a roughly array structure as shown in Figure 2, or it may be other structures, such as petal-shaped or scattered, and it may be regular or irregular. The dielectric element 35 is configured to apply an alternating electric field to the patient's tumor site. The temperature sensor 34 is configured to detect the temperature of the patient's body surface attached to the electrode sheet 13 and output a temperature detection signal to the adapter 20. In this embodiment, the multiplexed signal lines 19 of the flexible circuit board 31 are respectively arranged in a one-to-one correspondence with the multiple column groups of the electrode unit 33, and are configured to transmit the alternating current signal generated by the electric field generator 30 to the dielectric element 35 in each electrode unit 33 in the corresponding column group. That is, the dielectric components 35 in the same column group are short-circuited via the same dual-purpose signal line 19 on the flexible circuit board 31, while the dielectric components 35 in different column groups are connected in parallel via different dual-purpose signal lines 19 on the flexible circuit board 31. The dual-purpose signal lines 19 on the flexible circuit board 31 are electrically connected to the first cable 15 and then to the electric field generator 30 via the adapter 20. Furthermore, the dual-purpose signal lines 19 on the flexible circuit board 31 receive the AC signal generated by the electric field generator 30 via the first cable 15 and the adapter 20.

[0130] Each electrode unit 33 of the electrode sheet 13 has three operating modes. In the first mode, the electrode unit 33 applies an AC signal via the dielectric element 35. In the second mode, the temperature sensor 34 detects or collects the temperature of the patient's body surface to which the corresponding electrode unit 33 is applied. In the third mode, the application of the AC signal and the temperature detection and collection are stopped. The first, second, and third modes do not overlap in time. That is, the time periods during which the dielectric element 35 of the electrode unit 33 applies the AC signal are staggered and do not overlap with the time periods during which the temperature sensor 34 detects the temperature. The electrode unit 33 can cyclically switch between applying the AC signal via its dielectric element 35 and detecting the temperature via its temperature sensor 34, that is, the electrode unit 33 can cyclically switch between the first and second modes. The electrode unit 33 can also cyclically switch between the first, second, and third modes, that is, the electrode unit 33 cyclically switches between applying the AC signal via the dielectric element 35, collecting or detecting the temperature via the temperature sensor 34, and then cessation of applying the AC signal and continuing to collect the temperature.

[0131] Multiple grounding wires 18 are provided in a one-to-one correspondence with the multiple row groups of electrode units 33. These wires are used to sequentially short-circuit the temperature sensors 34 of each electrode unit 12 in each row group to ground. Specifically, the ground terminals 34-1 of the temperature sensors 34 in the same row group are all short-circuited via the same grounding wire 18 on the flexible circuit board 31. The ground terminals 34-1 of the temperature sensors 34 in different row groups are connected in parallel via different grounding wires 18 on the flexible circuit board 31. During the temperature detection period, only one of the multiple grounding wires 18 is connected at any one time; the other three are disconnected.

[0132] Each of the multiplexed dual-purpose signal lines 19 is further configured to short-circuit the signal terminal 34-2 of the temperature sensor 34 of at most one electrode unit 33 in each row group to an external device for receiving a detection signal. Each of the multiplexed dual-purpose signal lines 19 is connected to a different signal terminal 34-2 of the temperature sensor 34 to prevent the dual-purpose signal line 19 from subsequently outputting duplicate signals. Specifically, when the number of electrode units 33 in a row group is the same as the number of dual-purpose signal lines 19, each dual-purpose signal line 19 is electrically connected to the signal terminal 34-2 of the temperature sensor 34 of a different electrode unit 33 in the row group. When the number of electrode units 33 in a row group is less than the number of dual-purpose signal lines 19, at least one dual-purpose signal line 19 is not electrically connected to the signal terminal 34-2 of the temperature sensor 34 of an electrode unit 33, and each of the remaining dual-purpose signal lines 19 is electrically connected to the signal terminal 34-2 of the temperature sensor 34 of a different electrode unit 33 in the row group. In this embodiment, the external device for receiving the detection signal is an adapter 20. The signal terminals 34 - 2 of the temperature sensors 34 in different column groups are connected in parallel via different dual-purpose signal lines 19 on the flexible circuit board 31. The signal terminals 34 - 2 of the temperature sensors 34 in the same column group are all short-circuited to the same dual-purpose signal line 19 on the flexible circuit board 31.

[0133] In this embodiment, when each electrode unit 33 is equipped with a temperature sensor 34 for temperature detection, the above-mentioned circuit design is used to reduce the number of conductors in the first cable 15, thereby preventing the cable from becoming thicker and the cable from becoming harder, which increases the difficulty of fixing the cable; at the same time, it is prevented that the increase in the number of conductors in the first cable 15 affects the adhesion effect between the electrode sheet 13 and the corresponding body surface of the patient's tumor site. The grounding wires 18 and dual-purpose signal wires 19 embedded in the flexible circuit board 31 are a total of 9 lines. Specifically, in this embodiment, the grounding wires 18 embedded in the flexible circuit board 11 are 4 lines, and the dual-purpose signal wires 19 are 5 lines. The number of grounding wires 18 is related to the number M of row groups of the electrode units 33, which is greater than or equal to the number of row groups of the electrode units 33, and M is a positive integer. The number of dual-purpose signal wires 19 is related to the number N of column groups of the electrode units 33, which is greater than or equal to the number of column groups of the electrode units 33, and N is a positive integer. The number of lines L embedded in the flexible circuit board 31 of the electrode sheet 13 is equal to the sum of the number of ground lines 18 and the number of dual-purpose signal lines 19. In this embodiment, the number of ground lines 18 is equal to the number M of row groups of electrode units 33, and the number of dual-purpose signal lines 19 is equal to the number N of column groups of electrode units 33.

[0134] Multiple electrode units 33 are arranged in a roughly two-dimensional array, spaced apart, on the flexible circuit board 31. As shown in FIG2 , the electrode sheet 13 in this embodiment includes 20 electrode units 33 and 20 temperature sensors 34 corresponding to the electrode units 33. The 20 electrode units 33 are arranged in an array of four rows and six columns. The first and fourth rows each contain four electrode units 33, and the second and third rows each contain six electrode units 33. The four electrode units 33 in each of the first and fourth rows are located in each of the second to fifth columns, and the six electrode units 33 in each of the second and third rows are located in each of the first to sixth columns. The four electrode units 33 in the first row are divided into Region 1. The electrode units 33 in the first column of the second row, the first column of the third row, and the second and third columns of the fourth row are divided into Region 2. The electrode units 33 in the sixth column of the second row, the sixth column of the third row, and the fourth and fifth columns of the fourth row are divided into Region 3. The electrode units 33 in the second and third columns of the second row and the second and third columns of the third row are divided into Region 4. The electrode units 33 in the fourth and fifth columns of the second row and the fourth and fifth columns of the third row are divided into Region 5. Each region (1-5) corresponds to a column group. In other embodiments, the 20 electrode units 33 may also be arranged in other ways. Of course, in other embodiments, the electrode sheet 13 may also have other numbers of electrode units 33. In short, the implementation of the present invention is not limited by the number and arrangement of the electrode units 33 of the electrode sheet 13.

[0135] Each electrode unit 33 includes a dielectric element 35 and a temperature sensor 34. In the embodiments shown in Figures 3 and 4, the dielectric element 35 can be a dielectric ceramic sheet or a polymer dielectric layer composed of a polymer material. The temperature sensor 34 can be a thermistor element. Of course, in other embodiments, the temperature sensor 34 can also be other temperature sensors besides thermistors, which can be set at any position on the electrode unit 33. In this embodiment, each dielectric element 35 has a through-hole (unnumbered) running through the middle, and each through-hole (unnumbered) of the dielectric element 35 accommodates a corresponding temperature sensor 34. Each electrode unit 33 can also include a diode 36. The diode 36 is connected in series with the temperature sensor 34 of the same electrode unit 33, which can prevent the reverse flow of current to prevent the detection signal from other electrode units 33 from affecting the temperature sensor 34.

[0136] As shown in Figures 3 and 4, the electrode sheet 13 of this embodiment includes four grounding wires 18, each of which is used to ground the ground terminals 34-1 of the temperature sensors 34 in the same row group. The four grounding wires 18 of the electrode sheet 13 are respectively a first grounding wire 18-1, a second grounding wire 18-2, a third grounding wire 18-3, and a fourth grounding wire 18-4. Of the four row groups of the electrode sheet 13, the first row group consists of electrode units 33-1 to 33-5, the second row group consists of electrode units 33-6 to 33-10, the third row group consists of electrode units 33-11 to 33-15, and the fourth row group consists of electrode units 33-16 to 33-20. Specifically, the first grounding wire 18-1 is used to ground the electrode units 33-1 to 33-5 in the first row group; the second grounding wire 18-2 is used to ground the electrode units 33-6 to 33-10 in the second row group; the third grounding wire 18-3 is used to ground the electrode units 33-11 to 33-15 in the third row group; and the fourth grounding wire 18-4 is used to ground the electrode units 33-16 to 33-20 in the fourth row group. It should be noted that these grounding wires 18 can be selectively closed or opened, which can be achieved by connecting each grounding wire 18 in series with a switch, which will be described in detail below. The above-mentioned "grounding the electrode unit 33" can refer to grounding the ground terminal 34-1 of the temperature sensor 34 in the electrode unit 33, or it can refer to connecting the diode 36 in series with the temperature sensor 34 of the same electrode unit 33 and grounding them together. In short, each ground line 18 short-circuits the ground terminals 34 - 1 of the temperature sensors 34 of all the electrode units 33 in each row group and connects them to the ground.

[0137] As shown in Figures 3 and 4, the electrode sheet 13 of this embodiment also includes five dual-purpose signal lines 19. One end of each dual-purpose signal line 19 is connected to all electrode units 33 in each column group, and the other end is connected to an adapter 20 for receiving temperature detection signals and transmitting AC signals. In other words, for each row group, each dual-purpose signal line 19 can choose to connect to one of the electrode units 33 or not connect to any electrode unit 33 in the row group to avoid the dual-purpose signal line 19 from subsequently outputting duplicate signals. Specifically, the five dual-purpose signal lines 19 of the electrode sheet 13 include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4, and a fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is connected to the dielectric elements 35 of the four electrode units 33, namely, electrode unit 33-1, electrode unit 33-6, electrode unit 33-11, and electrode unit 33-16, and the signal end 34-2 of the temperature sensor 34 of each of the four electrode units 33; one end of the second dual-purpose signal line 19-2 is connected to the dielectric elements 35 of the four electrode units 33, namely, electrode unit 33-2, electrode unit 33-7, electrode unit 33-12, and electrode unit 33-17, and the signal end 34-2 of the temperature sensor 34 of each of the four electrode units 33; one end of the third dual-purpose signal line 19-3 is connected to the dielectric elements 35 of the four electrode units 33, namely, electrode unit 33-3, electrode unit 33-8, and electrode unit 33-1, respectively. 3. Electrode unit 33-18: The dielectric elements 35 of each of the four electrode units 33 and the signal terminals 34-2 of each temperature sensor 34. One end of the fourth dual-purpose signal line 19-4 is simultaneously connected to the dielectric elements 35 of each of the four electrode units 33, namely electrode unit 33-4, electrode unit 33-9, electrode unit 33-14, and electrode unit 33-19, and the signal terminals 34-2 of each temperature sensor 34. One end of the fifth dual-purpose signal line 19-5 is simultaneously connected to the dielectric elements 35 of each of the four electrode units 33, namely electrode unit 33-5, electrode unit 33-10, electrode unit 33-15, and electrode unit 33-20, and the signal terminals 34-2 of the temperature sensor 34. In short, each dual-purpose signal line 19 parallel-circuits the dielectric elements 35 and the signal terminals 34-2 of each temperature sensor 34 of each electrode unit 33 in the same column group, and is used for connection to an external device. It should be noted that these dual-purpose signal lines 19 can selectively transmit AC signals or receive temperature detection signals. This can be achieved by connecting each dual-purpose signal line 19 in series with a bidirectional switch 55 and coordinating the closing or opening of the grounding line 18. This will be described in detail below.

[0138] The multiple grounding wires 18 and the multiplexed signal wires 19 are conductive traces embedded within the flexible printed circuit board 31. The flexible printed circuit board 31 is electrically connected to the first cable 15. The multiple grounding wires 18 and the multiplexed signal wires 19 embedded within the flexible printed circuit board 31 are electrically connected to corresponding wires (not shown) within the first cable 15.

[0139] The tumor electric field therapy system 100 of this embodiment includes at least one pair of electrode sheets 13 as described above, an adapter 20 electrically connected to the electrode sheets 13, and an electric field generator 30 electrically connected to the adapter 20. The adapter 20 is connected between the electrode sheets 13 and the electric field generator 30. The electric field generator 30 provides an AC signal to the dielectric elements 35 in the multiple electrode units 33 of the electrode sheet 13 via the adapter 20 and the dual-purpose signal line 19 of the electrode sheet 13, or receives temperature detection signals output by the temperature sensors 34 in the multiple electrode units 33. The adapter 20 transmits the AC signal generated by the electric field generator 30 to the dual-purpose signal line 19 of the electrode sheet 13 and is also configured to receive the temperature detection signal output by the multiplexed signal line 19 of the electrode sheet 13.

[0140] 3 and 4 , the adapter 20 includes: a first controller 51, multiple analog-to-digital converters 52 connected to the first controller 51, multiple sets of voltage dividers 53 and ground switches 54 corresponding to the multiple analog-to-digital converters 52, multiple sets of bidirectional switches 55 corresponding to the multiple analog-to-digital converters 52, a first communication unit 56, an AC signal line 57 connected to each set of bidirectional switches 55, and a first power module 58 connected to the first communication unit 56, the first controller 51, and the multiple analog-to-digital converters 52. The first power module 58 provides a DC power supply VCC to the electronic components of the adapter 20. The adapter 20 also includes multiple circuit lines (unnumbered). The multiple circuit lines (unnumbered) are electrically connected to the multiple ground lines 18 and the multiple dual-purpose signal lines 19 in the flexible circuit board 31 of the corresponding electrode sheet 13 through the first cables 15 of the corresponding electrode sheet 13. The multiple circuit lines (unnumbered) include multiple AC signal lines 57 that transmit alternating current signals to corresponding electrode sheets 13 and are electrically connected to the multiplexed signal lines 19 within the flexible circuit board 31 of the corresponding electrode sheet 3; multiple circuit lines (unnumbered) that are electrically connected one-to-one with the multiplexed signal lines 19 within the flexible circuit board 31 of the corresponding electrode sheet 13 and are used to power each temperature sensor 34 of the electrode sheet 13 or transmit the temperature detection signal of the electrode sheet 13; and multiple circuit lines (unnumbered) that are electrically connected one-to-one with the multiple ground lines 18 within the flexible circuit board 31 of the corresponding electrode sheet 13. The number L of circuit lines electrically connected by the adapter 20 to each electrode sheet 13 is equal to the sum of the number of rows and columns of the electrode units 33 of the electrode sheet 13 plus one; the number H of circuit lines electrically connected by the adapter 20 to each of the X electrode sheets 13 is equal to X times the number of circuit lines electrically connected to each electrode sheet 13, that is, H = XL = X*(M+N+1). The number of grounding switches 54 and bidirectional switches 55 is related to the number of electrode sheets 13. The number of grounding switches 54 and bidirectional switches 55 is the same as the number of electrode sheets 13 and is not less than the number of electrode sheets 13. Preferably, the number of grounding switches 54 and bidirectional switches 55 is the same as the number of electrode sheets 13. The following detailed description will only use the example of an electrode sheet 13 with 20 electrode units 33 and the adapter 20 for electrical connection.

[0141] Each group of grounding switches 54 is provided with a plurality of grounding switches 54. The plurality of grounding switches 54 are respectively connected to the adapter 20 and are respectively electrically connected to circuit lines (not numbered) corresponding one-to-one to the multiple grounding lines 18 of a corresponding electrode sheet 13, and are configured to control the conduction or disconnection of the multiple grounding lines 18. The circuit lines (not numbered) electrically connected one-to-one to the multiple grounding lines 18 of the electrode sheet 13 are grounded at one end near the grounding switches 54. The number of grounding switches 54 in each group of grounding switches 54 is related to the number of grounding lines 18 of the flexible circuit board 31 of the corresponding electrode sheet 13, and in this embodiment, the two are equal. As shown in Figures 3 or 4, in this embodiment, the plurality of grounding switches 54 are respectively a first grounding switch 54-1, a second grounding switch 54-2, a third grounding switch 54-3, and a fourth grounding switch 54-4. The plurality of grounding switches 54 in the same group each control the closing or disconnection of the corresponding grounding line 18 of the same electrode sheet 13. The first grounding switch 54-1 is used to control the closing or disconnection of the first grounding line 18-1 of the corresponding electrode sheet 13, and can further cooperate with the corresponding group of two-way switching switches 55 to control the power on and off of each temperature sensor 34 of the five electrode units 33 from electrode unit 33-1 to electrode unit 33-5 in the first row group 33 of the electrode sheet 13; the second grounding switch 54-2 is used to control the closing or disconnection of the second grounding line 18-2 of the electrode sheet 13, and can further cooperate with the corresponding group of two-way switching switches 55 to control the power on and off of each temperature sensor 34 of the five electrode units 33 from electrode unit 33-6 to electrode unit 33-10 in the second row group 33 of the electrode sheet 13; The third grounding switch 54-3 is used to control the closing or disconnection of the third grounding line 18-3 of the electrode sheet 13, and can then cooperate with the corresponding group of two-way switching switches 55 to control the power on and off of each temperature sensor 34 of the five electrode units 33, electrode unit 33-11 to electrode unit 33-15, in the third row group 33 of the electrode sheet 13; the fourth grounding switch 54-4 is used to control the closing or disconnection of the fourth grounding line 18-4 of the electrode sheet 13, and can then cooperate with the corresponding group of two-way switching switches 55 to control the power on and off of each temperature sensor 34 of the five electrode units 33, electrode unit 33-16 to electrode unit 33-20, in the fourth row group 33 of the electrode sheet 13. The above-mentioned grounding switch 54 can be a mechanical switch, such as a relay. The grounding switch 54 can also be an electronic switch, and each grounding switch 54 can be opened and closed by an additional first controller.

[0142] In this embodiment, the multiple groups of grounding switches 54 are all electronic switches. The first controller 51 is in communication with the multiple groups of grounding switches 54 and is configured to sequentially and cyclically control the opening and closing states of the multiple grounding switches 54 in each group of grounding switches 54 . This in turn sequentially connects each of the multiple grounding wires 18 of the corresponding electrode sheet 13 and coordinates the switching of the corresponding bidirectional switch 55 to continuously and in real time collect the patient's body surface temperature detected by all temperature sensors 34 on the electrode sheet 13 . The number of grounding switches 54 in each group is no less than the number of grounding wires 18 on the flexible circuit board 31 of the corresponding electrode sheet 13 . In this embodiment, the number of grounding switches 54 in each group is equal to the number of grounding wires 18 on the corresponding electrode sheet 13 .

[0143] Each set of bidirectional switches 55 includes a plurality of bidirectional switches 55. The plurality of bidirectional switches 55 in each set are connected to the adapter 20 and are electrically connected to circuit lines (not numbered) corresponding one-to-one to the dual-purpose signal lines 19 of a corresponding electrode sheet 13. The number of bidirectional switches 55 in each set of bidirectional switches 55 is related to the number of dual-purpose signal lines 19 of the flexible circuit board 31 of the corresponding electrode sheet 13, and is greater than or equal to the number of dual-purpose signal lines 19 of the flexible circuit board 31 of the corresponding electrode sheet 13. In this embodiment, the number of bidirectional switches 55 is equal to the number of dual-purpose signal lines 19 of the flexible circuit board 31 of the corresponding electrode sheet 13. Each bidirectional switch 55 has a signal acquisition terminal 1 marked as 1 and a signal input terminal 2 marked as 2. The signal acquisition terminals 1 of multiple bidirectional switches 55 in the same group are respectively electrically connected to corresponding detection channels in multiple detection channels of a corresponding group of analog-to-digital converters 52. The signal input terminals 2 of each bidirectional switch 55 in the same group are electrically connected to the corresponding same AC signal line 57, and are configured to control the multiplexed signal line 19 to connect to the corresponding AC signal line 57 to transmit alternating current signals or to connect to the corresponding detection channel of the corresponding group of analog-to-digital converters 52 to receive the temperature detection signal output by the temperature sensor 34.

[0144] As shown in Figures 3 and 4 , taking the electrical connection between one electrode sheet 13 and the adapter 20 as an example, in this embodiment having 20 electrode units 33, the plurality of bidirectional switches 55 are respectively a first bidirectional switch 55-1, a second bidirectional switch 55-2, a third bidirectional switch 55-3, a fourth bidirectional switch 55-4, and a fifth bidirectional switch 55-5. The plurality of bidirectional switches 55 in the same group each control a corresponding one of the multiplexed signal lines 19 of the same electrode sheet 13 to switch between transmitting an AC signal and transmitting a temperature detection signal. Specifically, the first bidirectional switch 55-1 is used to control the switching between the transmission of the AC signal and the transmission of the temperature detection signal by the first dual-purpose signal line 19-1 of the corresponding electrode sheet 13, thereby controlling the conduction of the dielectric elements 35 of the electrode units 33-1, 33-6, 33-11, and 33-16 in the first column group of the electrode sheet 13 and the conduction of the signal ends 34-2 of the temperature sensors 34 of the electrode units 33-1, 33-6, 33-11, and 33-16 in the first column group, and cooperating with the corresponding grounding switches 54-1, 54-2, 54-3, and 54-4, so that the first column of electrode units 33-1, 33-6, 33-11, and 33-16 transmits the AC signal to the patient or outputs the temperature detection signals collected by the temperature sensors 34 of these electrode units 33 to the corresponding analog-to-digital converter 52. signal; the second bidirectional switch 55-2 is used to control the switching of the second dual-purpose signal line 19-2 of the corresponding electrode sheet 13 between transmitting an AC signal and transmitting a temperature detection signal, thereby controlling the conduction of each dielectric element 35 of the electrode unit 33-2, electrode unit 33-7, electrode unit 33-12, and electrode unit 33-17 in the second column group of the electrode sheet 13 and the conduction of the signal end 34-2 of each temperature sensor 34 of the electrode unit 33-2, electrode unit 33-7, electrode unit 33-12, and electrode unit 33-17 in the second column group, and cooperating with the corresponding grounding switch 54-1, grounding switch 54-2, grounding switch 54-3, and grounding switch 54-4, so that the second column of electrode units 33-2, electrode unit 33-7, electrode unit 33-12, and electrode unit 33-17 transmits an AC signal to the patient or outputs the temperature detection signal collected by the temperature sensor 34 of these electrode units 33 to the corresponding analog-to-digital converter 52;The third bidirectional switch 55-3 is used to control the switching of the third dual-purpose signal line 19-3 of the corresponding electrode sheet 13 between transmitting an AC signal and transmitting a temperature detection signal, thereby controlling the conduction of the dielectric elements 35 of the electrode units 33-3, 33-8, 33-13, and 33-18 in the third column group of the electrode sheet 13 and the conduction of the signal terminals 34-2 of the temperature sensors 34 of the electrode units 33-3, 33-8, 33-13, and 33-18 in the third column group, and cooperating with the corresponding grounding switches 54-1, 54-2, 54-3, and 54-4, so that the third column of electrode units 33-3, 33-8, 33-13, and 33-18 transmits an AC signal to the patient or outputs the temperature detection signals collected by the temperature sensors 34 of these electrode units 33 to the corresponding analog-to-digital converter 52. The fourth bidirectional switch 55-4 is used to control the switching of the fourth dual-purpose signal line 19-4 of the corresponding electrode sheet 13 between transmitting an AC signal and transmitting a temperature detection signal, thereby controlling the conduction of the dielectric elements 35 of the electrode units 33-4, 33-9, 33-14, and 33-19 in the fourth column group of the electrode sheet 13 and the conduction of the signal terminals 34-2 of the temperature sensors 34 of the electrode units 33-4, 33-9, 33-14, and 33-19 in the fourth column group, and cooperating with the corresponding grounding switches 54-1, 54-2, 54-3, and 54-4, so that the fourth column of electrode units 33-4, 33-9, 33-14, and 33-19 transmits an AC signal to the patient or outputs the temperature detection signals collected by the temperature sensors 34 of these electrode units 33 to the analog-to-digital converter 52;The fifth bidirectional switch 55-5 is used to control the switching of the fifth dual-purpose signal line 19-5 of the corresponding electrode sheet 13 between transmitting alternating current signals and transmitting temperature detection signals, thereby controlling the conduction of the dielectric elements 35 of the electrode units 33-5, 33-10, 33-15, and 33-20 in the fifth column group of the electrode sheet 13 and the conduction of the signal ends 34-2 of the temperature sensors 34 of the electrode units 33-5, 33-10, 33-15, and 33-20 in the fifth column group, and cooperating with the corresponding grounding switches 54-1, 54-2, 54-3, and 54-4, so that the fifth column of electrode units 33-5, 33-10, 33-15, and 33-20 transmit alternating current signals to the patient or output the temperature detection signals collected by the temperature sensors 34 of these electrode units 33 to the corresponding analog-to-digital converter 52. When the signal input terminal 2 of each set of bidirectional switches 55 is on and the signal acquisition terminal 1 is off, an AC signal can be transmitted to the dielectric element 35 of each electrode unit 33 of the corresponding electrode sheet 13. When the signal acquisition terminal 1 of each set of bidirectional switches 55 is on and the signal input terminal 2 is off, the bidirectional switches 55 can cooperate with each grounding switch 54 in the corresponding set of grounding switches 54 to transmit the temperature detection signal collected by the temperature sensor 34 of each electrode element 33 on the electrode sheet 13 in a time-sharing manner. The bidirectional switches 55 can be mechanical switches, such as relays. Alternatively, they can be electronic switches, and each bidirectional switch 55 can be switched by an additional first controller 51.

[0145] In this embodiment, the multiple sets of bidirectional switches 55 are all electronic switches. The first controller 51 is in communication with the multiple sets of bidirectional switches 55 and is configured to control the multiple bidirectional switches 55 in each set of bidirectional switches 55 to switch between their respective signal acquisition terminals 1 and signal input terminals 2, and to coordinate the closing or opening of the corresponding grounding switches 54 to continuously monitor the patient's body surface temperature detected by all temperature sensors 34 on the electrode sheet 13 or to transmit an AC signal to the patient.

[0146] In this embodiment, each set of analog-to-digital converters 52 is electrically connected to the signal acquisition terminals 1 of the plurality of bidirectional switching switches 55 in the corresponding set of bidirectional switching switches 55 through a multi-channel circuit line (not numbered) within the adapter 20, and is configured to receive the temperature detection signal transmitted by the multiplexed signal line 19 of the corresponding electrode sheet 13, and convert the temperature detection signal from an analog signal to a digital signal. Each set of analog-to-digital converters 52 includes a plurality of detection channels A, B, C, D, and E, and each detection channel A, B, C, D, and E is used to connect to a corresponding one of the multiplexed signal lines 19 through the corresponding bidirectional switching switch 55. As shown in Figure 3 or Figure 4, each set of analog-to-digital converters 52 includes a total of five detection channels A, B, C, D, and E, which are respectively the first detection channel A, the second detection channel B, the third detection channel C, the fourth detection channel D, and the fifth detection channel E. The first detection channel A is connected to the first dual-purpose signal line 19-1 via the signal acquisition terminal 1 of the first bidirectional switch 55-1. The second detection channel B is connected to the second dual-purpose signal line 19-2 via the signal acquisition terminal 1 of the second bidirectional switch 55-2. The third detection channel C is connected to the third dual-purpose signal line 19-3 via the signal acquisition terminal 1 of the third bidirectional switch 55-3. The fourth detection channel D is connected to the fourth dual-purpose signal line 19-4 via the signal acquisition terminal 1 of the fourth bidirectional switch 55-4. The fifth detection channel E is connected to the fifth dual-purpose signal line 19-5 via the signal acquisition terminal 1 of the fifth bidirectional switch 55-5. Each detection channel A, B, C, D, and E is configured to receive a temperature detection signal acquired by the temperature sensor 34 of the electrode unit 33 to which the corresponding dual-purpose signal line 19 is connected. In addition, each detection channel A, B, C, D, and E is connected to a first power supply module 58 via a corresponding voltage divider resistor 53 within the adapter 20, which is used to provide a detection voltage to the detection channel A, B, C, D, and E. The first power supply module 58 provides direct current power.

[0147] In this embodiment, the first communication unit 56 is configured to acquire the digital signals output by the multiple analog-to-digital converters 52 and transmit the digital signals to the electric field generator 30. The electric field generator 30 is further configured to control and adjust the voltage of the AC signal provided to the multiple electrode units 33 of the electrode sheet 13 based on the received digital signals. For example, when any of the multiple digital signals received exceeds a preset threshold, indicating that the temperature detected by at least one dielectric element 35 in the electrode sheet 13 exceeds a preset threshold temperature (e.g., 41°C, 42°C, etc.), the voltage of the AC signal output by the electric field generator 30 can be appropriately reduced to prevent the electrode units 33 of the electrode sheet 13 from overheating when the AC signal is applied, thereby preventing low-temperature burns on the patient's skin. The above-mentioned preset threshold temperature and preset threshold value can be determined based on human safety thresholds. The first communication unit 56 is controlled by the first controller 51 and serially transmits the digital signals converted by the multiple analog-to-digital converters 52. In this embodiment, the preset temperature threshold can be a value within the range of 36°C to 45°C.

[0148] 5 and 6 , in this embodiment, the first power module 58 is electrically connected to the second power module 32 of the electric field generator 30 and is configured to supply power to the first controller 51, the multiple analog-to-digital converters 52, and the first communication unit 56 of the adapter 20. A first connector 60 is provided between each electrode sheet 13 and the adapter 20. The first connector 60 is adapted to connect the corresponding electrode sheet 13 to the adapter 20. The first connector 60 includes a first plug 61 disposed at the end of the first cable 15 away from the electrode sheet 13 and a first socket 62 disposed on the adapter 20. The first plug 61 and the first socket 62 are press-type spring connectors, meaning that the first connector 60 connects the adapter 20 to the electrode sheet 13 using a connector. Each first cable 15 has five wires electrically connected one-to-one to the bidirectional switches 55 in the corresponding group and four wires electrically connected one-to-one to the grounding switches 54 in the corresponding group. That is, each first connector 60 is electrically connected to a corresponding set of bidirectional switches 55 and a corresponding set of grounding switches 54 of the adapter 20 through 9 wires; and is connected to the electric field generator 30 through a corresponding AC signal line 57 of the adapter 20.

[0149] A second connector 70 is provided between the adapter 20 and the electric field generator 30. The second connector 70 is suitable for connecting the electric field generator 300 to the adapter 20. The adapter 20 also includes a second cable 25 connected to the second connector 70. The second connector 70 includes a second plug 71 located at the end of the second cable 25 away from the first controller 51 and a second socket 72 located on the electric field generator 30. The second plug 71 and the second socket 72 are push-type spring connectors, meaning that the second connector 70 connects the adapter 20 to the electric field generator 30 using a connector method. Each first connector 60, such as X1, Y1, X2, and Y2, is connected to the second connector 70 via a corresponding AC signal line 57. The first connectors 60, such as X1, Y1, X2, and Y2, are also connected to a corresponding set of grounding switches 54 and a corresponding set of analog-to-digital converters 52. Each first connector 60 is connected to the second connector 70 and a corresponding set of analog-to-digital converters 52 via a corresponding set of bidirectional switches 55. The second cable 25 has eight conductors, including four conductors 1 to 4 electrically connected to corresponding AC signal lines 57 for transmitting alternating current signals, a conductor 5 electrically connected to the data receiving line RX of the first communication unit 56, a conductor 6 electrically connected to the data transmitting line TX of the first communication unit 56, a conductor 7 electrically connected to the VCC power line of the first power module 58, and a conductor 8 electrically connected to the GND line of the first power module 58. A second connector 70 is connected to the first communication unit 56 via the data receiving line RX and the data transmitting line TX. The VCC pin of the second connector 70 is connected to the VVC power line of the first power module 58, and the GND pin of the second connector 70 is connected to the GND line of the first power module 58 and is grounded. The VCC pin of the second connector 70 is also connected to the corresponding set of voltage dividers 53 and the corresponding set of analog-to-digital converters 52 via the VCC power line of the first power module 58.

[0150] 5 and 7 , the electric field generator 30 includes a second power module 32, a second controller 37, an AC signal generator 39, a second communication unit 38, and a set of AC signal switches 40. The VCC pin of the second connector 70 is electrically connected to the VCC power line of the second power module 32, and the GND pin of the second connector 70 is grounded via the GND line of the second power module 32. The second power module 32 is also connected to and powered by the second controller 37 and the AC signal generator 39. The second communication unit 38 is electrically connected to the wire 5 of the second connector 70 via its data receive line RX and to the wire 6 of the second connector 70 via its data transmit line TX, thereby enabling information exchange between the electric field generator 30 and the adapter 20. The second controller 37 is also electrically connected to the second communication unit 38, the AC signal generator 39, and a set of AC signal switches 40. The second controller 37 is configured to control the opening and closing of each AC signal switch 40 in the set of AC signal switches 40 and adjust the parameters of the AC signal applied by the AC signal generator 39 based on the relevant digital signals received by the second communication unit 38 from the adapter 20. The AC signal generator 39 is electrically connected to the conductors 1 to 4 of the second connector 70 that transmit the AC signal through the set of AC signal switches 40. The set of AC signal switches 40 includes a plurality of AC signal switches 40, and the plurality of AC signal switches 40 are arranged in a one-to-one correspondence with the plurality of electrode sheets 13. Each AC signal switch 40 is electrically connected to a corresponding conductor 1, 2, 3, or 4 of the second connector 70 that transmits the AC signal through an AC signal line 41-1, 41-2, 41-3, or 41-4, and is electrically connected to the corresponding electrode sheet 13 through the corresponding conductor 1, 2, 3, or 4 of the second connector 70, thereby transmitting the AC signal to each electrode sheet 13. The AC signal generator 39 is electrically connected to the set of AC signal switches 40 via an AC signal line 41. Specifically, the number of AC signal switches 40 in the electric field generator 30 is related to the number of electrode pads 13. In this embodiment, the number of AC signal switches 40 is equal to the number of electrode pads 13, and both are four. The AC signal switches 40 include a first AC signal switch 40-1, a second AC signal switch 40-2, a third AC signal switch 40-3, and a fourth AC signal switch 40-4, which are electrically connected to the wires 1 to 4 of the second connector 70, respectively.One end of the first AC signal switch 40-1 is electrically connected to the AC signal generator 39 through the AC signal line 41 of the electric field generator 30, and the other end is electrically connected to the corresponding conductor 1 for transmitting the alternating current signal in the second connection 70 through an AC signal line 41-1 and electrically connected to the AC signal line 57 at the port X1 of the adapter 20 through the conductor 1 of the second connector 70, the AC signal line 57 at the port X1 of the adapter 20 is electrically connected to the first connector 60, and the first connector 60 at the port X1 of the adapter 20 is electrically connected to the corresponding electrode sheet 13, so as to control whether the AC signal generator 39 transmits the alternating current signal to the electrode sheet 13 electrically connected to the port X1 of the adapter 20; One end of the second AC signal switch 40-2 is electrically connected to the AC signal generator 39 through the AC signal line 41 of the electric field generator 30, and the other end is electrically connected to the corresponding conductor 2 for transmitting AC signals in the second connection 70 through an AC signal line 41-2 and electrically connected to the AC signal line 57 at the port Y1 of the adapter 20 through the conductor 2 of the second connector 70, the AC signal line 57 at the port Y1 of the adapter 20 is electrically connected to the first connector 60, and the first connector 60 at the port Y1 of the adapter 20 is electrically connected to the corresponding electrode sheet 13, so as to control whether the AC signal generator 39 transmits the AC signal to the electrode sheet 13 electrically connected to the port Y1 of the adapter 20; One end of the third AC signal switch 40-3 is electrically connected to the AC signal generator 39 through the AC signal line 41 of the electric field generator 30, and the other end is electrically connected to the corresponding wire 3 for transmitting AC signals in the second connection 70 through an AC signal line 41-3 and electrically connected to the AC signal line 57 at the port X2 of the adapter 20 through the wire 3 of the second connector 70, the AC signal line 57 at the port X2 of the adapter 20 is electrically connected to the first connector 60, and the first connector 60 at the port X2 of the adapter 20 is electrically connected to the corresponding electrode sheet 13, so as to control whether the AC signal generator 39 transmits an AC signal to the electrode sheet 13 electrically connected to the port X2 of the adapter 20; One end of the fourth AC signal switch 40-4 is electrically connected to the AC signal generator 39 through the AC signal line 41 of the electric field generator 30, and the other end is electrically connected to the corresponding conductor 4 for transmitting AC signals in the second connection 70 through an AC signal line 41-4 and electrically connected to the AC signal line 57 at the port Y2 of the adapter 20 through the conductor 4 of the second connector 70, the AC signal line 57 at the port Y2 of the adapter 20 is electrically connected to the first connector 60, and the first connector 60 at the port Y2 of the adapter 20 is electrically connected to the corresponding electrode sheet 13, so as to control whether the AC signal generator 39 transmits AC signals to the electrode sheet 13 electrically connected to the port Y1 of the adapter 20.

[0151] The working principle of the tumor electric field treating system 100 of this embodiment will be described in detail below with reference to FIG. 3 to FIG. 5 .

[0152] Specifically, when it is necessary to detect the temperature of each electrode unit 33 of a certain electrode sheet 13, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls the signal acquisition end 1 of each of the multiple bidirectional switching switches 55 in a group of bidirectional switching switches 55 electrically connected to the electrode sheet 13 to be turned on and the signal input end 2 to be turned off, so as to disconnect the AC signal applied to the electrode sheet 13; at the same time, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls each of the grounding switches 54 in a group of grounding switches 54 electrically connected to the electrode sheet 13 to be turned on in sequence. At this time, the temperature detection signals collected by each temperature sensor 34 of each electrode unit 33 in each row group of the electrode sheet 13 can be collected in sequence through multiple detection channels A, B, C, D, and E of a group of analog-to-digital converters 52 corresponding to the electrode sheet 13. Each detection channel A, B, C, D, and E of each group of analog-to-digital converters 52 simultaneously collects only the temperature detection signals of the temperature sensors 34 corresponding to the electrode units 33 of the electrode sheet 13 in the same row group. The temperature detection signals can be represented by voltage values, indicating that only one of the four grounding switches 54 in the group of grounding switches 54 corresponding to the electrode sheet 13 is turned on at the same time, while the other three are turned off. The five bidirectional switches 55 in the group of bidirectional switches 55 corresponding to the group of analog-to-digital converters 52 are all switched to their respective signal acquisition terminals 1 so that the dual-purpose signal lines 19 of the electrode sheet 13 are electrically connected to the corresponding detection channels A, B, C, D, and E of the corresponding analog-to-digital converters 52 in a one-to-one correspondence and are turned on. With this arrangement, the group of analog-to-digital converters 52 can collect the voltage values ​​of all temperature sensors 34 in the electrode units 33 in the same row group that are short-circuited with the grounding line 18 corresponding to the turned-on grounding switch 54.

[0153] Specifically, when the grounding switch 54-1 is closed, the grounding switches 54-2, 54-3, and 54-4 are all opened, and the first bidirectional switch 55-1, the second bidirectional switch 55-2, the third bidirectional switch 55-3, the fourth bidirectional switch 55-4, and the fifth bidirectional switch 55-5 are all switched to their respective signal acquisition terminals 1, the temperature sensors 34 of the electrode units 33-1 to 33-5 of the first row group are energized, and the temperature sensors 34 of the electrode units 33-6 to 33-20 of the remaining row groups are de-energized, and the electrode units 33-1, 33-6, 33-11, and 33-20 of the first detection channel A of the analog-to-digital converter 52 of this group are short-circuited. Since only the ground terminal 34-1 of the temperature sensor 34 of electrode unit 33-1 is connected to ground, while the ground terminals 34-1 of the temperature sensors 34 of electrode units 33-6, 33-11, and 33-16 are disconnected, and each electrode unit 33 is provided with a diode 36 connected in series with the temperature sensor 34, the resistance of the temperature sensor 34 of electrode unit 33-1 is not affected. Therefore, only the temperature sensor 34 of electrode unit 33-1 is effectively operating on the first detection channel A of the set of analog-to-digital converters 52. The temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 34 of electrode unit 33-1. Similarly, the voltage value collected by the second detection channel B of the set of analog-to-digital converters 52 is the voltage value of the temperature sensor 34 of electrode unit 33-2. The voltage value collected by the third detection channel C of the set of analog-to-digital converters 52 is the voltage value of the temperature sensor 34 of electrode unit 33-3. The voltage value collected on the fourth detection channel D of the ADC 52 is the voltage value of the temperature sensor 34 of the electrode unit 33-4. The voltage value collected on the fifth detection channel E of the ADC 52 is the voltage value of the temperature sensor 34 of the electrode unit 33-5.

[0154] When the grounding switch 54-2 is closed, the grounding switches 54-1, 54-3, and 54-4 are all opened, and the first bidirectional switch 55-1, the second bidirectional switch 55-2, the third bidirectional switch 55-3, the fourth bidirectional switch 55-4, and the fifth bidirectional switch 55-5 are all switched to their respective signal acquisition terminals 1, the temperature sensors 34 of the electrode units 33-6 to 33-10 of the second row group are energized, and the temperature sensors 34 of the electrode units 33-1 to 33-5 and the electrode units 33-11 to 33-20 of the remaining row groups are de-energized, and the electrode units 33-1, 33-6, 33-11, and 33-20 of the first detection channel A of the analog-to-digital converter 52 of this group are short-circuited. Since only the ground terminal 34-1 of the temperature sensor 34 of electrode unit 33-6 is connected to ground, while the ground terminals 34-1 of the temperature sensors 34 of electrode units 33-1, 33-11, and 33-16 are all disconnected, and each electrode unit 33 is provided with a diode 36 connected in series with the temperature sensor 34, this does not affect the resistance of the temperature sensor 34 of electrode unit 33-6. Therefore, only the temperature sensor 34 of electrode unit 33-6 is effectively operating on the first detection channel A of the set of analog-to-digital converters 52. At this time, the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 34 of electrode unit 33-6. Similarly, the voltage value collected by the second detection channel B of the set of analog-to-digital converters 52 is the voltage value of the temperature sensor 34 of electrode unit 33-7. The voltage value collected by the third detection channel C of the set of analog-to-digital converters 52 is the voltage value of the temperature sensor 34 of electrode unit 33-8. The voltage value collected on the fourth detection channel D of the set of analog-to-digital converters 52 is the voltage value of the temperature sensor 34 of the electrode unit 33-9. The voltage value collected on the fifth detection channel E of the set of analog-to-digital converters 52 is the voltage value of the temperature sensor 34 of the electrode unit 33-10.

[0155] When the grounding switch 54-3 is closed, the grounding switches 54-1, 54-2, and 54-4 are all opened, and the first bidirectional switch 55-1, the second bidirectional switch 55-2, the third bidirectional switch 55-3, the fourth bidirectional switch 55-4, and the fifth bidirectional switch 55-5 are all switched to their respective signal acquisition terminals 1, the temperature sensors 34 of the electrode units 33-11 to 33-15 of the third row group are energized, and the temperature sensors 34 of the electrode units 33-1 to 33-10 and the electrode units 33-16 to 33-20 of the remaining row groups are de-energized, and the electrode units 33-1, 33-6, and 33-11 are short-circuited on the first detection channel A of the analog-to-digital converter 52 of this group. Since only the ground terminal 34-1 of the temperature sensor 34 of electrode unit 33-11 is connected to the ground, while the ground terminals 34-1 of the temperature sensors 34 of electrode units 33-1, 33-6, and 33-16 are all disconnected, and each electrode unit 33 is provided with a diode 36 connected in series with the temperature sensor 34, it will not affect the resistance value of the temperature sensor 34 of electrode unit 33-11. Therefore, only the temperature sensor 34 of electrode unit 33-11 is effectively operating on the first detection channel A of the set of analog-to-digital converters 52. At this time, the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 34 of electrode unit 33-11. Similarly, the voltage value collected by the second detection channel B in the set of analog-to-digital converters 52 is the voltage value of the temperature sensor 34 of electrode unit 33-12. The voltage value collected by the third detection channel C in the set of analog-to-digital converters 52 is the voltage value of the temperature sensor 34 of the electrode unit 33-13. The voltage value collected by the fourth detection channel D in the set of analog-to-digital converters 52 is the voltage value of the temperature sensor 34 of the electrode unit 33-14. The voltage value collected by the fifth detection channel E in the set of analog-to-digital converters 52 is the voltage value of the temperature sensor 34 of the electrode unit 33-15.

[0156] When the grounding switch 54-4 is closed, the grounding switches 54-1, 54-2, and 54-3 are all opened, and the first bidirectional switch 55-1, the second bidirectional switch 55-2, the third bidirectional switch 55-3, the fourth bidirectional switch 55-4, and the fifth bidirectional switch 55-5 are all switched to their respective signal acquisition terminals 1, the temperature sensors 34 of the electrode units 33-16 to 33-20 of the fourth row group are energized, and the temperature sensors 34 of the electrode units 33-1 to 33-15 of the remaining row groups are de-energized, and the electrode units 33-1, 33-6, 33-11, and 33-16 are short-circuited on the first detection channel A of the analog-to-digital converter 52 of the group. Since only the ground terminal 34-1 of the temperature sensor 34 of electrode unit 33-16 is connected to ground, while the ground terminals 34-1 of the temperature sensors 34 of electrode units 33-1, 33-6, and 33-11 are all disconnected, and each electrode unit 33 is provided with a diode 36 connected in series with the temperature sensor 34, the resistance of the temperature sensor 34 of electrode unit 33-16 will not be affected. Therefore, only the temperature sensor 34 of electrode unit 33-16 is effectively operating on the first detection channel A of the set of analog-to-digital converters 52. At this time, the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 34 of electrode unit 33-16. Similarly, the voltage value collected by the second detection channel B of the set of analog-to-digital converters 52 is the voltage value of the temperature sensor 34 of electrode unit 33-17. The voltage value collected by the third detection channel C of the set of analog-to-digital converters 52 is the voltage value of the temperature sensor 34 of electrode unit 33-18. The voltage value collected on the fourth detection channel D in the group of analog-to-digital converters 52 is the voltage value of the temperature sensor 34 of the electrode unit 33-19. The voltage value collected on the fifth detection channel E in the group of analog-to-digital converters 52 is the voltage value of the temperature sensor 34 of the electrode unit 33-20. Thus, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 can collect the temperature detection signals of the temperature sensors 34 of all the electrode units 33 of a certain electrode sheet 13 by controlling a group of bidirectional switches 55 and a group of grounding switches 54 that are electrically connected to the electrode sheet 13. Similarly, the temperature detection signals of the temperature sensors 34 of each electrode unit 33 of other electrode sheets 13 can be obtained.

[0157] The first controller 51, the plurality of analog-to-digital converters 52, and the plurality of bidirectional switches 55 can automatically perform operations according to pre-programmed program codes. For example, the first controller 51 first controls all the bidirectional switches 55 in the corresponding group of bidirectional switches 55 to switch to the signal acquisition terminal 1, so that the signal acquisition terminals 1 of the bidirectional switches 55 are all turned on and the signal input terminals 2 are all turned off, so that the dual-purpose signal lines 19 of the corresponding electrode sheets 13 are electrically connected to the corresponding group of analog-to-digital converters 52. Then, the grounding switch 54-1 in the corresponding group of grounding switches 54 is closed, and the remaining grounding switches 54-2 to 54-4 in the group of grounding switches 54 are turned off. During this period, the group of analog-to-digital converters 52 is turned on and off. Each detection channel A, B, C, D, and E of the analog-to-digital converter 52 acquires the temperature detection signals of each temperature sensor 34 of each electrode unit 33 located in the first row group of the corresponding electrode sheet 13, converts them into digital signals, and stores them in a separately provided memory. Then, after a preset interval, the first controller 51 closes the grounding switch 54-2 in the group of grounding switches 54 and opens the grounding switches 54-1, 54-3, and 54-4 in the group of grounding switches 54. During this period, each detection channel A, B, C, D, and E of the analog-to-digital converter 52 acquires the temperature detection signals of each temperature sensor 34 located in the second row group of each electrode unit 33. By sequentially opening each grounding switch 54 in the group of grounding switches 54, the temperature detection signals of all temperature sensors 34 on the electrode sheet 13 can be obtained. Similarly, through this operation, the temperature detection signals of all temperature sensors 34 on at least one pair of electrode sheets 13 can be obtained.

[0158] The tumor electric field therapy system 100 of the present application can realize real-time and comprehensive monitoring of the temperature of all electrode units 33 on the electrode sheet 13 without increasing the weight of the electrode sheet 13 or adding the core of the first cable 15 electrically connected to the electrode sheet 13, and then determine whether the electrode sheet 13 is qualified based on the obtained temperature detection signal; or determine whether the temperature sensor 34 of the electrode sheet 13 is faulty or abnormal based on the obtained temperature detection signal, and determine whether the electrode sheet 13 needs to be replaced based on the number of faulty or abnormal temperature sensors 34 obtained; or if the electrode sheet is qualified, identify the type of the electrode sheet based on the obtained temperature detection signal; or if the electrode sheet is qualified, determine whether the electrode unit 33 of the electrode sheet 13 is overheated based on the obtained temperature detection signal, and then control the alternating electric signal applied to the electrode sheet 13 or the electrode units 33 of the corresponding column of the electrode sheet 13, so as to avoid low-temperature burns on the patient's body surface when tumor treatment is performed through the electrode sheet 13. Furthermore, the flexible circuit board 31 of the electrode sheet 13 of the present application electrically connects the dielectric element 35 of the same electrode unit 33 and the signal terminal 34-2 of the temperature sensor 34 via the same dual-purpose signal line 19. While enabling the dual-purpose signal line 19 to transmit both an alternating current signal and a direct current signal for temperature signal acquisition and the collected temperature detection signal, the flexible circuit board 31 also significantly reduces the number of conductive traces (ground line 18, dual-purpose signal line 19) arranged thereon, thereby reducing the wiring difficulty of the flexible circuit board 31, simplifying the manufacturing process, reducing the weight of the flexible circuit board 31, and lowering manufacturing costs. The electrode sheet 13 of the present application can also switch between applying an alternating current signal for tumor treatment and transmitting a direct current signal for temperature acquisition and the collected temperature detection signal through the combined control of a grounding switch 54 electrically connected to the ground line 18 arranged thereon and a bidirectional switching switch 55 electrically connected to the dual-purpose signal line 19.

[0159] When it is necessary to apply an alternating current signal to the patient through the electrode units 33 of a certain electrode sheet 13, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls to disconnect all the grounding switches 54 in a group of grounding switches 54 corresponding to the electrode sheet 13, and at the same time controls to switch all the bidirectional switching switches 55 in a group of bidirectional switching switches 55 corresponding to the electrode sheet 13 to their respective signal input terminals 2, so that the signal acquisition terminals 1 of the bidirectional switching switches 55 are all disconnected and the signal input terminals 2 are all turned on, so that all the dual-purpose signal lines 19 of the electrode sheet 13 are electrically connected to an AC signal line 57 corresponding to the adapter 20 and the electrode sheet 13, thereby transmitting the alternating current signal to the electrode units 33 of the electrode sheet 13.When the temperature detection signals of the temperature sensors 34 of all the electrode units 33 of the electrode sheet 13 are much lower than the preset temperature threshold stored in the electric field generator 20 or the adapter 20, the electric field generator 30 controls the AC signal generator 39 through its second controller 37 to continue to generate an AC signal with an increased voltage or current amplitude or a constant voltage or current amplitude, and then transmits it to the corresponding pair of electrode sheets 13 through a corresponding AC signal line 57 of the adapter 20, so that the pair of electrode sheets 13 continue to apply the AC signal; when the temperature detection signals of the temperature sensors 34 of all the electrode units 33 of the electrode sheet 13 are lower than but close to the preset temperature threshold stored in the electric field generator 30 or the adapter 20, the electric field generator 30 controls the AC signal generator 39 through its second controller 37 to continue to generate an AC signal with an increased voltage or current amplitude or a constant voltage or current amplitude, and then transmits it to the corresponding pair of electrode sheets 13 through a corresponding AC signal line 57 of the adapter 20, so that the pair of electrode sheets 13 continue to apply the AC signal; The electric field generator 30 can reduce the voltage or current of the alternating current signal generated by the AC signal generator 39 through the second controller 37, thereby reducing the voltage or current of the alternating current signal applied to the pair of electrode sheets 13; when it is detected that the temperature detection signal of the temperature sensor 34 of an electrode unit 33 in a certain electrode sheet 13 is greater than the preset temperature threshold, the electric field generator 30 controls the AC signal switch 40 electrically connected to the electrode sheet 13 to disconnect through the second controller 37 to stop applying the alternating current signal to the electrode sheet 13; or the second controller 37 of the electric field generator 30 or the first controller 21 of the adapter 20 controls all the bidirectional switching switches 55 in a group of bidirectional switching switches 55 electrically connected to the electrode sheet 13 to disconnect from their signal terminals. The signal input terminal 2 is switched to the signal acquisition terminal 1, that is, the signal acquisition terminals 1 of all the bidirectional switches 55 electrically connected to the electrode sheet 13 are all turned on and the signal input terminals 2 are all disconnected, thereby temporarily stopping the application of the alternating electric signal to the electrode sheet 13; or, when it is detected that the temperature detection signal of the temperature sensor 34 of an electrode unit 33 of a certain electrode sheet 13 is greater than the preset temperature threshold, the second controller 37 of the electric field generator 30 controls the AC signal switch electrically connected to the electrode sheet 13 to continue to be turned on, and the second controller 37 of the electric field generator 30 or the first controller 21 of the adapter 20 controls a bidirectional switch 55 electrically connected to the electrode unit 33 of the electrode sheet 13 to be turned off. Signal input terminal 2 switches to its signal acquisition terminal 1, and the second controller 37 of the electric field generator 30 or the first controller 21 of the adapter 20 simultaneously controls the remaining bidirectional switches 55 electrically connected to the electrode units 33 whose temperature detection signals of the electrode sheet 13 do not exceed the preset temperature threshold and are in different columns from the electrode units 33 whose temperature detection signals exceed the preset temperature threshold to continue to maintain electrical connection with their respective signal input terminals 2. This stops applying the AC signal to all electrode units 33 in the column where the electrode unit 33 whose temperature detection signals of the electrode sheet 13 exceed the preset temperature threshold, and continues applying the AC signal to the electrode units 33 in the remaining columns where the temperature detection signals of the electrode sheet 13 do not exceed the preset temperature threshold. This implements the method for controlling the application of the AC signal based on the temperature detection signal of the tumor electric field therapy system 100.

[0160] In the embodiment of the present application, the grounding switch 54 electrically connected to each of the multiple grounding lines 18 of the electrode sheet 13 and the bidirectional switch 55 electrically connected to each of the multiple dual-purpose signal lines 19 of the electrode sheet 13 are both provided in the adapter 20. However, in other embodiments, the grounding switch 54 electrically connected to the grounding line 18 and the bidirectional switch 55 electrically connected to the dual-purpose signal line 19 can also be provided on the electrode sheet 13 or provided in the electric field generator 30, which will not be described in detail here. In addition, the analog-to-digital converter 52 provided in the adapter 20 can also be provided in the electric field generator 30 and directly controlled by the second controller 37.

[0161] The present embodiment provides an electrode sheet temperature detection method, which is applied to the electrode sheet 13 or the tumor electric field treatment system 100 described above, as shown in FIG8 , and includes the following steps:

[0162] Step 210: Control the bidirectional switch 55 electrically connected to each electrode unit 33 of the electrode sheet 13 to disconnect the AC signal applied to the dielectric element 35 of each electrode unit 33 of the electrode sheet 13 and connect the DC signal applied to the signal terminal 34-2 of the temperature sensor 34 of each electrode unit 33 of the electrode sheet 13;

[0163] Step 220 : sequentially turning on the grounding switches 54 electrically connected to the grounding terminals 34 - 1 of the temperature sensors 34 of the electrode units 33 of the electrode sheet 13 to obtain temperature detection signals from the temperature sensors 34 of the electrode units 33 of the electrode sheet 13 .

[0164] Step 210 is specifically as follows: controlling the bidirectional switch 55 electrically connected to each electrode unit 33 of the electrode sheet 13 to switch from the end thereof electrically connected to the AC signal to the end thereof electrically connected to the DC signal, that is, controlling the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch from its signal input end 2 to its signal acquisition end 1; or

[0165] The bidirectional switching switch 55 electrically connected to each electrode unit 33 of the electrode sheet 13 is controlled to switch the dielectric element 35 of each electrode unit 33 of the electrode sheet 13 from the on state to the off state, and at the same time, the signal end 34-2 of the temperature sensor 34 of each electrode unit 33 of the electrode sheet 13 is switched from the off state to the on state.

[0166] The electrode sheet temperature detection method of the present application can quickly and accurately obtain the temperature of all electrode units of the electrode sheet; and based on the obtained temperature detection signals of all temperature sensors of the electrode sheet, it can be judged whether the temperature sensors of the electrode sheet are faulty, whether there is an abnormality, whether the electrode sheet is qualified, and whether it needs to be replaced; it can also be judged whether each electrode unit of the electrode sheet is overheated based on the obtained temperature detection signals of all temperature sensors of the electrode sheet when each temperature sensor of the electrode sheet is normal, and then control the AC signal applied to the electrode sheet or applied to each electrode unit of the electrode sheet; it can also be used to identify the type of electrode sheet when there is no abnormality in the temperature detection signals of each temperature sensor of the electrode sheet.

[0167] 9 , an embodiment of the present application further provides a method for detecting electrode sheet quality, which includes the above steps 210 and 220 , and after step 220 , further includes:

[0168] Step 221: determining whether the temperature sensor 34 of each electrode unit 33 of the electrode sheet 13 has an abnormality or a fault according to the acquired temperature detection signal of the temperature sensor 34 of each electrode unit 33 of the electrode sheet 13;

[0169] Step 222: Determine whether the electrode sheet is qualified based on whether the temperature sensor 34 of the electrode sheet 13 is abnormal or malfunctioning.

[0170] The determination of whether the electrode sheet is qualified in step 222 further includes the following steps:

[0171] When the temperature sensor 34 of each electrode unit 33 of the electrode sheet 13 is abnormal or fails, the electrode sheet is determined to be unqualified; or

[0172] When there is no abnormality or failure in the temperature sensor 34 of each electrode unit 33 of the electrode sheet 13 , the electrode sheet is determined to be qualified.

[0173] 10 , an embodiment of the present application further provides an electrode replacement detection method, which includes the above-mentioned steps 210 and 220 , and after step 220 , further includes:

[0174] Step 230: determining whether the temperature sensor 34 of each electrode unit 33 of the electrode sheet 13 has an abnormality or a fault according to the acquired temperature detection signal of the temperature sensor 34 of each electrode unit 33 of the electrode sheet 13;

[0175] Step 240: Determine whether the electrode sheet 13 needs to be replaced based on whether the temperature sensor 34 of the electrode sheet 13 is abnormal or malfunctioning.

[0176] The step 240 of determining whether the electrode sheet needs to be replaced further includes the following steps:

[0177] When each temperature sensor 34 of the electrode sheet 13 is abnormal or faulty and the number of abnormal or faulty temperature sensors 34 exceeds a preset threshold, it is determined that the electrode sheet needs to be replaced; or

[0178] When the number of abnormal or faulty temperature sensors 34 in the electrode sheet 13 does not exceed a preset threshold, it is determined that the electrode sheet does not need to be replaced.

[0179] The preset threshold is 20% of the total number of all temperature sensors on the electrode sheet.

[0180] As shown in FIG11 , the present application further provides a method for detecting abnormal electrode temperature, the method comprising the above steps 210 and 220 , and after step 220 , further comprising:

[0181] Step 250 : Detecting temperature anomalies at each electrode unit 33 of the electrode sheet 13 based on the obtained temperature detection signals of the temperature sensors 34 of each electrode unit 33 of the electrode sheet 13 .

[0182] The temperature abnormality detection of each electrode unit 33 of the electrode sheet 13 in step 250 specifically includes the following steps:

[0183] Step 251: Compare the obtained temperature detection signal of each electrode unit 33 of the electrode sheet 13 with a preset temperature threshold;

[0184] Step 252: Determine whether there is temperature abnormality in each electrode unit 33 of the electrode sheet according to the comparison result.

[0185] The comparison results in step 252 include not exceeding the preset temperature threshold and exceeding the preset temperature threshold. Not exceeding the preset temperature threshold includes being far below the preset temperature threshold and being close to the preset temperature threshold. The preset temperature threshold is 40°C-42°C. Preferably, the preset temperature threshold is 40.5°C-41.5°C. Preferably, the preset temperature threshold is 41°C-41.5°C. Preferably, the preset temperature threshold is 41°C.

[0186] The process of determining whether the temperature of each electrode unit 33 of the electrode sheet 13 is abnormal in step 252 is as follows:

[0187] Step 253: When the obtained temperature detection signal does not exceed the preset temperature threshold, it is determined that the electrode sheet 13 has no temperature abnormality; or

[0188] Step 254 : When the obtained temperature detection signal exceeds a preset temperature threshold, it is determined that the electrode sheet 13 has a temperature anomaly.

[0189] 12 , an embodiment of the present application further provides a method for controlling application of an AC signal for tumor therapeutic field therapy, comprising steps 210 and 220 described above, and after step 220, further comprising:

[0190] Step 260 : When it is determined that the electrode sheet does not need to be replaced, the AC signal applied to each electrode unit 33 of the electrode sheet 13 is controlled or adjusted according to the temperature detection signal of the temperature sensor 34 of each electrode unit 33 of the electrode sheet 13 .

[0191] The method for controlling application of an alternating current signal for tumor electric field therapy according to an embodiment of the present application may further include the above-mentioned steps 230 and 240 between steps 220 and 260 .

[0192] The method for controlling application of alternating current signals for tumor electric field therapy according to the embodiment of the present application may further include step 250 between step 240 and step 260 .

[0193] In step 260, controlling or adjusting the AC signal applied to each electrode unit 33 of the electrode sheet 13 further includes:

[0194] Step 261: When the temperature detection signals of the electrode units 33 of the electrode sheet 13 obtained do not exceed the preset temperature threshold, continue to apply the AC signal to the electrode units 33 of the electrode sheet 13; or

[0195] Step 262 : When a temperature detection signal among the acquired temperature detection signals of all the electrode units 33 of the electrode sheet 13 exceeds a preset temperature threshold, stop applying the AC signal to the electrode units 33 of the electrode sheet 13 .

[0196] The stopping of applying the AC signal to the electrode unit 33 of the electrode sheet 13 described in step 262 includes stopping applying the AC signal to all electrode units 33 of the electrode sheet 13, stopping applying the AC signal to the electrode unit 33 in the electrode sheet 13 whose temperature detection signal exceeds the preset temperature threshold, and stopping applying the AC signal to all electrode units 33 in the column where the electrode unit 33 in the electrode sheet 13 whose temperature detection signal exceeds the preset temperature threshold is located.

[0197] When the application of the AC signal to the electrode unit 33 in the electrode sheet 13 whose temperature detection signal exceeds the preset temperature threshold is stopped, the AC signal continues to be applied to the electrode unit 33 in the electrode sheet 13 whose temperature detection signal does not exceed the preset temperature threshold.

[0198] When the application of the AC signal to all electrode units 33 in the column where the electrode unit 33 whose temperature detection signal exceeds the preset temperature threshold in the electrode sheet 13 is located is stopped, the AC signal continues to be applied to all electrode units 33 in the column where the temperature detection signal does not exceed the preset temperature threshold and is in a different column from the electrode unit 33 whose temperature detection signal exceeds the preset temperature threshold in the electrode sheet 13.

[0199] The process of continuing to apply the AC signal to the electrode sheet 13 in step 261 is specifically as follows:

[0200] Step 263: When the temperature detection signal is much lower than the preset temperature threshold, continue to apply the AC signal to each electrode unit 33 of the electrode sheet 13 in a manner of increasing the voltage or current amplitude of the AC signal applied to each electrode unit 33 of the electrode sheet 13 or continue to apply the AC signal to each electrode unit 33 of the electrode sheet 13 in a manner of keeping the voltage or current amplitude of the AC signal applied to each electrode unit 33 of the electrode sheet 13 unchanged; or

[0201] Step 264: When the temperature detection signal approaches a preset temperature threshold, continue to apply the AC signal to each electrode unit 33 of the electrode sheet 13 in a manner that keeps the voltage or current amplitude of the AC signal applied to each electrode unit 33 of the electrode sheet 13 unchanged, or continue to apply the AC signal to each electrode unit 33 of the electrode sheet 13 in a manner that reduces the voltage or current amplitude of the AC signal applied to each electrode unit 33 of the electrode sheet 13.

[0202] 13 , an embodiment of the present application further provides a method for identifying an electrode sheet type, which includes the above-mentioned steps 210 and 220. When the electrode sheet 13 is qualified or each temperature sensor 34 of the electrode sheet 13 has no abnormality or failure, after step 220, the method further includes:

[0203] Step 270 : Identify the type of the electrode sheet 13 based on the acquired temperature detection signal of the temperature sensor 34 of each electrode unit 33 of the electrode sheet 13 .

[0204] The present application also provides a signal control method for tumor electric field therapy, which is used for the above-mentioned tumor electric field therapy system 100 or for the above-mentioned electrode sheet 13. The method includes: combining and controlling the grounding switch 54 and the bidirectional switching switch 55 electrically connected to the electrode sheet 13 so that each electrode unit 33 of the electrode sheet 13 switches between applying an alternating current signal and collecting a temperature detection signal.

[0205] As shown in FIG14 , the present application further provides a signal control method for tumor electric field therapy, which is used for the above-mentioned electrode sheet 13 , and the method comprises:

[0206] Step 310: Combine and control the grounding switch 54 and the bidirectional switch 55 electrically connected to the corresponding electrode sheet 13 to apply an AC signal to each electrode unit 33 of the electrode sheet 13 and execute step 320;

[0207] Step 320: Combine and control the grounding switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 to collect temperature detection signals of each electrode unit of the electrode sheet 13 in a row and execute step 330;

[0208] Step 330: Determine the combined control mode of the grounding switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 according to the collected temperature detection signal and execute step 340;

[0209] Step 340 : Control the working state of each electrode unit 33 of the electrode sheet 13 according to the determined combined control mode of the grounding switch 54 and the bidirectional switch 55 .

[0210] The operating state of each electrode unit 33 of the electrode sheet 13 described in step 340 includes at least one of: stopping applying the AC signal and continuing to collect the temperature detection signal; and stopping collecting the temperature detection signal and continuing to apply the AC signal. Continuing to apply the AC signal includes continuing to apply the AC signal in a manner of increasing the voltage or current amplitude of the currently applied AC signal, continuing to apply the AC signal in a manner of maintaining the voltage or current amplitude of the currently applied AC signal, or continuing to apply the AC signal in a manner of decreasing the voltage or current amplitude of the currently applied AC signal.

[0211] The operating state of each electrode unit 33 of the electrode sheet 13 is determined by the temperature detection signal collected by the electrode unit 33. The electrode units 33 of the electrode sheet 13 are divided into different areas. The combination of the grounding switch 54 and the bidirectional switch 55 controls each electrode unit 33 in each area to cyclically switch between applying an AC signal and collecting a temperature detection signal.

[0212] This embodiment of the present application provides another method 500 for detecting the temperature of an electrode sheet of a tumor treating field system 100. Referring to FIG. 15 , the temperature detection method 500 includes:

[0213] Step 510: disconnect the AC signal input to the electrode sheet 13, perform combination control on the multiple grounding switches 54 and the multiple bidirectional switches 55, and obtain the temperature detection signal of the temperature sensor 34 of the electrode sheet 13 corresponding to each combination in all combinations;

[0214] Step 520: sampling and converting the temperature detection signal detected by each temperature sensor 34 in the electrode sheet 13 to obtain a digital temperature signal;

[0215] Step 530: Transmit the digital temperature signal to the electric field generator 30 of the tumor electric field therapy system 100, so that the electric field generator 30 determines the temperature at the corresponding electrode unit 33 according to the digital temperature signal.

[0216] In step 510, “combined control of the plurality of grounding switches 54 and the plurality of bidirectional switches 55” specifically includes:

[0217] Step 511: placing all bidirectional switches 55 at the signal acquisition terminal 1 to conduct electrical connections between the signal terminals 34 - 2 of the temperature sensors 34 of all electrode units 33 and the corresponding analog-to-digital converters 52 ;

[0218] Step 512: Sequentially and individually closing one of the plurality of grounding switches 54 in a time-sharing manner to collect the temperature detection signals detected by the temperature sensors 34 of the electrode units 33 in the corresponding row group row by row.

[0219] In step 512 , sequentially and time-sharingly closing one of the plurality of grounding switches 54 can connect the detection channels electrically connected between the analog-to-digital converter 52 and each temperature sensor 34 in the row group corresponding to the closed grounding switch 54 .

[0220] In this way, the temperature detection signals of the corresponding temperature sensors 34 in each row group can be obtained in turn, and then after processing by the adapter 20 or the electric field generator 30, the corresponding temperatures of all electrode units 33 on the electrode sheet 13 can be obtained; thereby making the temperature detection of the patient's body surface more comprehensive and accurate.

[0221] For the tumor electric field therapy system 100 of the embodiment of the present application, the temperature of a single electrode unit 33 can also be detected as needed. The specific process of the method for performing temperature detection on a certain electrode unit 33 of the electrode sheet 13 is as follows: disconnect the input of the AC signal, place the bidirectional switch 55 corresponding to the column group where the electrode unit 33 that needs to be individually measured is located at the signal acquisition terminal 1, and place the remaining bidirectional switches 55 at the signal input terminal 2; at the same time, turn on and ground the grounding switch 54 corresponding to the row group where the electrode unit 33 that needs to be individually measured is located, and disconnect all the remaining grounding switches 54. In this way, the temperature detection signal of the temperature sensor 34 in the electrode unit 33 that needs to be individually measured can be sampled to obtain the temperature of the electrode unit 33. For example, if the electrode unit 33 that requires independent temperature measurement is electrode unit 33-1, then the bidirectional switch 55-1 corresponding to electrode unit 33-1 is set to signal acquisition terminal 1, and the remaining bidirectional switches (55-2 through 55-5) are all set to signal input terminal 2. At the same time, the grounding switch 18-1 corresponding to electrode unit 33-1 is closed and grounded, and the remaining grounding switches (18-2 through 18-4) are all opened. In this way, the temperature of electrode unit 33-1 can be detected.

[0222] The present embodiment also provides another method 600 for applying an AC signal for tumor treating fields, which is applied to the aforementioned tumor treating fields system 100. Referring to FIG. 16 , the AC signal application method 600 includes:

[0223] Step 610: Determine the region (1-5) where the electrode unit 33 in the electrode sheet 13 to which the AC signal needs to be applied is located;

[0224] Step 611: Combining and controlling a plurality of grounding switches 54 and a plurality of bidirectional switching switches 55 electrically connected to the electrode sheet 13 to apply an AC signal.

[0225] In step 611, “combining and controlling the plurality of grounding switches 54 and the plurality of bidirectional switches 55 electrically connected to the electrode sheet 13” is specifically as follows:

[0226] Step 612: Disconnect all grounding switches 54 electrically connected to the electrode sheet 13;

[0227] Step 613: Determine the column groups where the electrode units 33 in the areas where the AC signal needs to be applied are located according to the areas where the electrode units 33 need to be applied.

[0228] Step 614: determining the bidirectional switches 55 electrically connected to the electrode units 33 in the column groups according to the column groups where the electrode units 33 to which the AC signals need to be applied are located;

[0229] Step 615: Control the bidirectional switching switch 55 electrically connected to the electrode unit 33 to which an AC signal needs to be applied so that the electrode unit 33 to which an AC signal needs to be applied is electrically connected to the AC signal line 57 to apply the AC signal; at the same time, control the remaining bidirectional switching switches 55 so that the electrical connection between each electrode unit 33 in the area where no AC signal needs to be applied and the AC signal line 57 is disconnected to stop applying the AC signal.

[0230] In step 615, "electrically connecting the electrode units to which an AC signal needs to be applied to the AC signal line 57 to apply the AC signal and disconnecting the electrical connection between the electrode units 33 in the area where the AC signal does not need to be applied and the AC signal line 57 to stop applying the AC signal" is achieved by placing the bidirectional switching switches 55 electrically connected to the electrode units 33 in the column groups corresponding to the areas (1-5) in the electrode sheet 13 to which the AC signal is to be applied at their signal input terminals 2, and placing all the bidirectional switching switches 55 electrically connected to the electrode units 33 in the remaining column groups at the signal acquisition terminal 1.

[0231] The first controller 51 or the electric field generator 30 in the adapter 20 of the tumor electric field therapy system 100 of the embodiment of the present application is provided with a preset quantity threshold, a first preset temperature t1, a second preset temperature t2 and a preset temperature threshold t0, wherein the first preset temperature t1 is lower than the second preset temperature t2, and the second preset temperature t2 is lower than the preset temperature threshold t0.

[0232] The present embodiment further provides a method 700 for applying an AC signal based on a temperature detection signal, which is used in the above-mentioned tumor treating field system 100. Referring to FIG. 17 , the application method 700 includes:

[0233] Step 710: Start the tumor treating field system 100;

[0234] Step 711: Combine and control the grounding switch 54 and the bidirectional switch 55 electrically connected to the corresponding electrode sheet 13 to apply an AC signal to each electrode unit 33 of the electrode sheet 13;

[0235] Step 712: Combine and control the grounding switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 to obtain the temperature of each electrode unit 33 of the electrode sheet 13;

[0236] Step 713: Determine whether there is an electrode unit 33 whose temperature exceeds the first preset temperature t1. If there is no electrode unit 33 whose temperature exceeds the first preset temperature t1, execute step 714. If there is an electrode unit 33 whose temperature exceeds the first preset temperature t1, execute step 715.

[0237] Step 714: Continue applying the AC signal to each electrode unit 33 of the electrode sheet 13 in a manner of increasing the voltage or current amplitude of the currently applied AC signal and return to step 712;

[0238] Step 715: Determine whether there is an electrode unit 33 whose temperature exceeds the second preset temperature t2; if there is no electrode unit 33 whose temperature exceeds the second preset temperature t2, execute step 716; if there is an electrode unit 33 whose temperature exceeds the second preset temperature t2, execute step 717;

[0239] Step 716: Continue applying the AC signal to each electrode unit 33 of the electrode sheet 13 in a manner that keeps the voltage or current amplitude of the currently applied AC signal unchanged and return to step 712;

[0240] Step 717: Determine whether there is an electrode unit 33 whose temperature exceeds the preset temperature threshold t0. If there is no electrode unit 33 whose temperature exceeds the preset temperature threshold t0, execute step 718; if there is an electrode unit whose temperature exceeds the preset temperature threshold t0, execute step 719;

[0241] Step 718: Continue applying the AC signal to all electrode units 33 of the electrode sheet 13 in a manner of reducing the voltage or current amplitude of the currently applied AC signal and return to step 712;

[0242] Step 719: Determine the number of over-temperature regions and execute step 720, wherein the over-temperature region is a region containing electrode units whose temperatures exceed the preset temperature threshold t0, and the non-over-temperature region is a region in which the temperatures of all electrode units do not exceed the preset temperature threshold t0;

[0243] Step 720: Determine whether the number of over-temperature areas exceeds a preset number threshold. If the number of over-temperature areas exceeds the preset number threshold, execute step 721. If the number of over-temperature areas does not exceed the preset number threshold, execute step 724.

[0244] Step 721: Stop applying the AC signal to each electrode unit 33 of the electrode sheet 13 and execute step 722;

[0245] Step 722: Combine and control the grounding switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 to obtain the temperature of each electrode unit 33 of the electrode sheet 13 and execute step 723;

[0246] Step 723: Determine whether there is an electrode unit 33 with a temperature exceeding the first preset temperature t1. If no electrode unit 33 with a temperature exceeding the first preset temperature t1 exists on the electrode sheet 13, the process returns to step 711. If no electrode unit 33 with a temperature exceeding the first preset temperature t1 exists on the electrode sheet 13, the process returns to step 722.

[0247] Step 724: Distinguish between an over-temperature area and a non-over-temperature area based on whether the area contains an electrode unit 33 whose temperature exceeds the preset temperature threshold t0. If the area is an over-temperature area, execute step 725; if the area is a non-over-temperature area, execute step 726.

[0248] Step 725: Stop applying the AC signal to each electrode unit 33 in the over-temperature area and execute step 731;

[0249] Step 726: Determine whether the temperature of each electrode unit 33 in the non-overtemperature area does not exceed the first preset temperature t1. If the temperature of each electrode unit 33 in the non-overtemperature area does not exceed the first preset temperature t1, execute step 727. If the temperature of each electrode unit 33 in the non-overtemperature area exceeds the first preset temperature t1, execute step 728.

[0250] Step 727: Continue applying the AC signal to each electrode unit 33 in the non-overtemperature area of ​​the electrode sheet 13 by increasing the voltage or current amplitude of the currently applied AC signal and execute step 731;

[0251] Step 728: Determine whether the temperature of each electrode unit 33 in the non-overtemperature area does not exceed the second preset temperature t2. If the temperature of each electrode unit 33 in the non-overtemperature area does not exceed the second preset temperature t2, execute step 729. If the temperature of each electrode unit 33 in the non-overtemperature area exceeds the second preset temperature t2, execute step 730.

[0252] Step 729: Continue applying the AC signal to each electrode unit 33 in the non-overtemperature region of the electrode sheet 13 in a manner that maintains the voltage or current amplitude of the currently applied AC signal unchanged and execute step 731;

[0253] Step 730: Continue applying the AC signal to each electrode unit 33 in the non-overtemperature area of ​​the electrode sheet 13 by reducing the voltage or current amplitude of the currently applied AC signal and execute step 731;

[0254] Step 731: Combining and controlling the grounding switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 to re-acquire the temperature of each electrode unit 33 of the electrode sheet 13 and selecting to execute step 732 or step 734. The temperature of each electrode unit 33 of the electrode sheet 13 includes the temperature of each electrode unit 33 in the over-temperature area and the temperature of each electrode unit 33 in the non-over-temperature area.

[0255] Step 732: Determine whether the temperature of each electrode unit 33 in the over-temperature area does not exceed the first preset temperature t1. If the temperature of each electrode unit 33 in the over-temperature area does not exceed the first preset temperature t1, execute step 733. If the temperature of each electrode unit 33 in the over-temperature area exceeds the first preset temperature t1, return to step 731.

[0256] Step 733: re-determine the area as a non-overtemperature area and execute step 734;

[0257] Step 734: Determine whether the temperatures of the electrode units 33 in the non-overtemperature area do not exceed the first preset temperature t1. If the temperatures of the electrode units 33 in the non-overtemperature area do not exceed the first preset temperature t1, execute step 735. If any of the temperatures of the electrode units 33 in the non-overtemperature area exceeds the first preset temperature t1, execute step 736.

[0258] Step 735: Continue applying the AC signal to each electrode unit 33 in the non-overtemperature area by increasing the voltage or current amplitude of the currently applied AC signal and return to step 712;

[0259] Step 736: Determine whether the temperatures of the electrode units 33 in the non-overtemperature region do not exceed the second preset temperature t2. If the temperatures of the electrode units 33 in the non-overtemperature region do not exceed the second preset temperature t2, execute step 737. If any of the temperatures of the electrode units 33 in the non-overtemperature region exceeds the second preset temperature t2, execute step 738.

[0260] Step 737: Continue applying the AC signal to each electrode unit 33 in the non-overtemperature area in a manner that maintains the voltage or current amplitude of the currently applied AC signal unchanged and return to step 712;

[0261] Step 738: Determine whether the temperatures of the electrode units 33 in the non-overtemperature area do not exceed the preset temperature threshold t0. If the temperatures of the electrode units 33 in the non-overtemperature area do not exceed the preset temperature threshold t0, execute step 739. If any of the temperatures of the electrode units 33 in the non-overtemperature area exceeds the preset temperature threshold t0, return to step 719.

[0262] Step 739 : Continue applying the AC signal to each electrode unit 33 in the non-overtemperature area by reducing the voltage or current amplitude of the currently applied AC signal and return to step 712 .

[0263] 18 , the process of combining and controlling the grounding switch 54 and the bidirectional switch 55 electrically connected to the corresponding electrode sheet 13 in step 711 to apply an AC signal to each electrode unit 33 of the electrode sheet is as follows:

[0264] Disconnect all grounding switches 54 electrically connected to the corresponding electrode sheets 13, and simultaneously switch all bidirectional switches 55 electrically connected to the corresponding electrode sheets 13 to one end that applies an AC signal to each electrode unit 33; or

[0265] Disconnect all grounding switches 54 electrically connected to the corresponding electrode sheet 13, and simultaneously switch all bidirectional switches 55 electrically connected to the corresponding electrode sheet 13 to one end that electrically connects each electrode unit 33 to the AC signal line 57; or

[0266] All grounding switches 54 electrically connected to the corresponding electrode sheets 13 are disconnected, and at the same time, all bidirectional switches 55 electrically connected to the corresponding electrode sheets 13 are switched to their respective signal input terminals 2 .

[0267] The process of obtaining the temperature of each electrode unit 33 of the electrode sheet 13 in steps 712, 722, and 731 is specifically as follows:

[0268] Controlling the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch all ends from the end where the AC signal is applied to each electrode unit 33 to the end where the temperature of each electrode unit 33 is collected, and sequentially closing the grounding switch 54 electrically connected to the electrode unit 33 of the electrode sheet 13 in a time-division manner to obtain the temperature of each electrode unit 33 of the electrode sheet 13; or

[0269] Controlling the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch all signal input terminals 2 for applying an AC signal to each electrode unit 33 to its signal acquisition terminal 1, and sequentially closing the grounding switches 54 electrically connected to the electrode units 33 of the electrode sheet 13 in a time-division manner to obtain the temperature of each electrode unit 33 of the electrode sheet 13; or

[0270] Controlling the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch the electrode sheet 13 from being electrically connected to the AC signal line 57 to being electrically connected to the corresponding analog-to-digital converter 53, and sequentially closing the grounding switch 54 electrically connected to each electrode unit 33 of the electrode sheet 13 in a time-division manner to obtain the temperature of each electrode unit 33 of the electrode sheet 13; or

[0271] The bidirectional switching switch 55 electrically connected to the electrode sheet 13 is controlled to switch each electrode unit 33 of the electrode sheet 13 from transmitting an AC signal to transmitting a DC signal or a temperature detection signal, and the grounding switch 54 electrically connected to each electrode unit 33 of the electrode sheet 13 is closed in sequence in a time-sharing manner to obtain the temperature of each electrode unit 33 of the electrode sheet 13.

[0272] The first preset temperature in steps 713, 723, 726, 732, and 734 is 40°C to 40.3°C, preferably 40.2°C. The second preset temperature in steps 715, 728, and 736 is 40.4°C to 40.6°C, preferably 40.5°C. The preset temperature threshold in steps 717 and 738 is 41°C to 41.5°C, preferably 41°C. The preset quantity threshold in step 720 is preferably 2.

[0273] The process of continuing to apply the AC signal in steps 714, 716, 718, 727, 729, 730, 735, 737, and 739 is specifically as follows:

[0274] disconnecting the grounding switch 54 electrically connected to the electrode unit 33 to which the AC signal needs to be continuously applied, and simultaneously controlling the bidirectional switch 55 electrically connected to the electrode unit 33 to which the AC signal needs to be continuously applied to connect the AC signal transmission path electrically connected to the electrode unit 33 to which the AC signal needs to be continuously applied, thereby continuing to apply the AC signal to the electrode unit 33 to which the AC signal needs to be continuously applied; or

[0275] Disconnect the grounding switch 54 electrically connected to the electrode unit 33 to which the AC signal needs to be continuously applied, and at the same time control the bidirectional switch 55 electrically connected to the electrode unit 33 to which the AC signal needs to be continuously applied to switch from its respective signal acquisition end 1 to its respective signal input end 2 so as to continue to apply the AC signal to the electrode unit 33 to which the AC signal needs to be continuously applied; or

[0276] Disconnect the grounding switch 54 electrically connected to the electrode unit 33 to which the AC signal needs to be continuously applied, and simultaneously control the signal input terminals 2 of the bidirectional switches 55 electrically connected to the electrode unit 33 to which the AC signal needs to be continuously applied so that the AC signal continues to be applied to the electrode unit 33; or

[0277] Disconnect the grounding switch 54 electrically connected to the electrode unit 33 to which the AC signal needs to be continuously applied, and simultaneously control the bidirectional switch 55 electrically connected to the electrode unit 33 to which the AC signal needs to be continuously applied so that the respective signal input terminals 2 are closed and the signal acquisition terminals 1 are disconnected, thereby continuing to apply the AC signal to the electrode unit 33 to which the AC signal needs to be continuously applied; or

[0278] Disconnect the grounding switch 54 electrically connected to the electrode unit 33 to which the AC signal needs to continue to be applied, and at the same time control the bidirectional switching switch 55 electrically connected to the electrode unit 33 to which the AC signal needs to continue to be applied so that the electrode unit 33 to which the AC signal needs to continue to be applied switches from transmitting the temperature detection signal to applying the AC signal.

[0279] Increasing the voltage or current amplitude of the currently applied AC signal in step 714, step 727, and step 735 specifically involves boosting the voltage of the currently applied AC signal in a manner of a DC voltage amplitude increment of 0.03 V per second.

[0280] The method of continuing to apply the AC signal in a manner of reducing the voltage or current amplitude of the currently applied AC signal as described in steps 718, 730, and 739 is specifically to continue to apply the AC signal in a manner of reducing the voltage or current amplitude of the currently applied AC signal by 5V and lasting for 3 minutes.

[0281] The process of stopping applying the AC signal to each electrode unit 33 of the electrode sheet 13 in step 721 is specifically as follows:

[0282] Control the bidirectional switch 55 electrically connected to the electrode sheet 13 to disconnect the electrical connection between each electrode unit 33 of the electrode sheet 13 and the AC signal line 57; or

[0283] Control the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch from the end where the AC signal is applied to each electrode unit 33 to the end where the temperature is collected by each electrode unit 33; or

[0284] Control the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch all the signal input terminals 2 for applying AC signals to the electrode units 33 to the signal collection terminals 1 thereof; or

[0285] Controlling the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch the electrode sheet 13 from electrically connecting each electrode unit 33 thereof to the AC signal line 57 to electrically connecting each electrode unit 33 to the corresponding analog-to-digital converter 53; or

[0286] The bidirectional switch 55 electrically connected to the electrode sheet 13 is controlled to switch each electrode unit 33 of the electrode sheet 13 from transmitting an AC signal to transmitting a DC signal or a temperature detection signal.

[0287] The process of stopping applying the AC signal to each electrode unit 33 in the over-temperature area in step 725 is specifically as follows:

[0288] Control the bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature area to disconnect the electrical connection between each electrode unit 33 in the over-temperature area and the AC signal line 57; or

[0289] Control the bidirectional switches 55 electrically connected to the electrode units 33 in the over-temperature zone to switch all ends thereof from applying an AC signal to the electrode units 33 in the over-temperature zone to collecting temperature from the electrode units 33 in the over-temperature zone; or

[0290] Control the bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature area to switch all signal input terminals 2 for applying AC signals to each electrode unit 33 in the over-temperature area to their signal collection terminals 1; or

[0291] Controlling the bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature region to switch each electrode unit 33 in the over-temperature region from being electrically connected to the AC signal line 57 to being electrically connected to the corresponding analog-to-digital converter 53; or

[0292] The bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature area is controlled to switch each electrode unit 33 in the over-temperature area from transmitting an AC signal to transmitting a DC signal or a temperature detection signal.

[0293] In the above control method 700, the tumor electric field therapy system 100 includes at least two pairs of electrodes 13 for alternately applying alternating electric fields with different directions. Each electrode 13 can alternately switch between applying an AC signal and transmitting a temperature detection signal.

[0294] The first controller 51 or electric field generator 30 in the adapter 20 of the tumor therapy field system 100 of the present embodiment further includes a third preset temperature t3. The third preset temperature t3 is higher than the second preset temperature t2 but still lower than the preset temperature threshold t0. The third preset temperature t3 is closer to the preset temperature threshold t0 than the second preset temperature t2. The present embodiment also provides an AC signal control method based on a temperature detection signal for use in the aforementioned tumor therapy field system. Referring to FIG. 18 , the AC signal control method 800 includes:

[0295] Step 810: Start the tumor treating field system 100;

[0296] Step 811: Combining and controlling the grounding switch 54 and the bidirectional switch 55 electrically connected to the corresponding electrode sheet 13 to apply an AC signal to each electrode unit 33 of the electrode sheet 13;

[0297] Step 812: Combine and control the grounding switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 to obtain the temperature of each electrode unit 33 of the electrode sheet 13;

[0298] Step 813: Determine whether there is an electrode unit 33 whose temperature exceeds the first preset temperature t1. If there is no electrode unit 33 whose temperature exceeds the first preset temperature t1, execute step 814. If there is an electrode unit 33 whose temperature exceeds the first preset temperature t1, execute step 815.

[0299] Step 814: Continue applying the AC signal to each electrode unit 33 of the electrode sheet 13 in a manner of increasing the voltage or current amplitude of the currently applied AC signal and return to step 812;

[0300] Step 815: Determine whether there is an electrode unit 33 whose temperature exceeds the second preset temperature t2; if there is no electrode unit 33 whose temperature exceeds the second preset temperature t2, execute step 816; if there is an electrode unit 33 whose temperature exceeds the second preset temperature t2, execute step 817;

[0301] Step 816: Continue applying the AC signal to each electrode unit 33 of the electrode sheet 13 in a manner that keeps the voltage or current amplitude of the currently applied AC signal unchanged and return to step 812;

[0302] Step 817: Determine whether there is an electrode unit 33 whose temperature exceeds the third preset temperature t3. If no electrode unit 33 has a temperature exceeding the third preset temperature t3, execute step 818; if there is an electrode unit 33 whose temperature exceeds the third preset temperature t3, execute step 819.

[0303] Step 818: Continue applying the AC signal to all electrode units 33 of the electrode sheet 13 in a manner of reducing the voltage or current amplitude of the currently applied AC signal and return to step 812;

[0304] Step 819: Determine whether there is an electrode unit 33 whose temperature exceeds the preset temperature threshold t0. If there is no electrode unit 33 whose temperature exceeds the preset temperature threshold t0, execute step 820; if there is an electrode unit whose temperature exceeds the preset temperature threshold t0, execute step 821;

[0305] Step 820: Continue applying the AC signal to all electrode units 33 of the electrode sheet 13 in a manner of reducing the voltage or current amplitude of the currently applied AC signal and return to step 812;

[0306] Step 821: Determine the number of over-temperature regions and execute step 822, wherein the over-temperature region is a region containing electrode units whose temperatures exceed a preset temperature threshold t0, and the non-over-temperature region is a region in which the temperatures of all electrode units do not exceed the preset temperature threshold t0;

[0307] Step 822: Determine whether the number of over-temperature areas exceeds a preset number threshold. If the number of over-temperature areas exceeds the preset number threshold, execute step 823. If the number of over-temperature areas does not exceed the preset number threshold, execute step 826.

[0308] Step 823: Stop applying the AC signal to each electrode unit 33 of the electrode sheet 13 and execute step 824;

[0309] Step 824: Combine and control the grounding switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 to obtain the temperature of each electrode unit 33 of the electrode sheet 13 and execute step 825;

[0310] Step 825: Determine whether there is an electrode unit 33 with a temperature exceeding the first preset temperature t1. If no electrode unit 33 with a temperature exceeding the first preset temperature t1 exists on the electrode sheet 13, the process returns to step 811. If no electrode unit 33 with a temperature exceeding the first preset temperature t1 exists on the electrode sheet 13, the process returns to step 824.

[0311] Step 826: Distinguish between an over-temperature area and a non-over-temperature area based on whether the area contains an electrode unit 33 whose temperature exceeds the preset temperature threshold t0. If the area is an over-temperature area, execute step 827; if the area is a non-over-temperature area, execute step 828.

[0312] Step 827: Stop applying the AC signal to each electrode unit 33 in the over-temperature area and execute step 835;

[0313] Step 828: Determine whether the temperature of each electrode unit 33 in the non-overtemperature area does not exceed the first preset temperature t1. If the temperature of each electrode unit 33 in the non-overtemperature area does not exceed the first preset temperature t1, execute step 829. If the temperature of each electrode unit 33 in the non-overtemperature area exceeds the first preset temperature t1, execute step 830.

[0314] Step 829: Continue applying the AC signal to each electrode unit 33 in the non-overtemperature area of ​​the electrode sheet 13 by increasing the voltage or current amplitude of the currently applied AC signal and execute step 835;

[0315] Step 830: Determine whether the temperature of each electrode unit 33 in the non-overtemperature area does not exceed the second preset temperature t2. If the temperature of each electrode unit 33 in the non-overtemperature area does not exceed the second preset temperature t2, execute step 831. If the temperature of each electrode unit 33 in the non-overtemperature area exceeds the second preset temperature t2, execute step 832.

[0316] Step 831: Continue applying the AC signal to each electrode unit 33 in the non-overtemperature area of ​​the electrode sheet 13 in a manner that maintains the voltage or current amplitude of the currently applied AC signal unchanged and execute step 835;

[0317] Step 832: Determine whether any of the electrode units 33 in the non-overtemperature region has a temperature exceeding the third preset temperature t3. If the temperature of any of the electrode units 33 in the non-overtemperature region does not exceed the third preset temperature t3, execute step 833. If any of the electrode units 33 in the non-overtemperature region has a temperature exceeding the third preset temperature t3, execute step 834.

[0318] Step 833: Continue applying the AC signal to each electrode unit 33 in the non-overtemperature area of ​​the electrode sheet 13 by reducing the voltage or current amplitude of the currently applied AC signal and execute step 835;

[0319] Step 834: Continue applying the AC signal to each electrode unit 33 in the non-overtemperature area of ​​the electrode sheet 13 in a manner that further reduces the voltage or current amplitude of the currently applied AC signal and execute step 835;

[0320] Step 835: Combining and controlling the grounding switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 to re-acquire the temperature of each electrode unit 33 of the electrode sheet 13 and selecting to execute step 836 or step 838. The temperature of each electrode unit 33 of the electrode sheet 13 includes the temperature of each electrode unit 33 in the over-temperature area and the temperature of each electrode unit 33 in the non-over-temperature area.

[0321] Step 836: Determine whether the temperature of each electrode unit 33 in the over-temperature area does not exceed the first preset temperature t1. If the temperature of each electrode unit 33 in the over-temperature area does not exceed the first preset temperature t1, execute step 837. If the temperature of each electrode unit 33 in the over-temperature area exceeds the first preset temperature t1, return to step 835.

[0322] Step 837: re-determine the area as a non-overtemperature area and execute step 838;

[0323] Step 838: Determine whether the temperatures of the electrode units 33 in the non-overtemperature area do not exceed the first preset temperature t1. If the temperatures of the electrode units 33 in the non-overtemperature area do not exceed the first preset temperature t1, execute step 839. If any of the temperatures of the electrode units 33 in the non-overtemperature area exceeds the first preset temperature t1, execute step 840.

[0324] Step 839: Continue applying the AC signal to each electrode unit 33 in the non-overtemperature area by increasing the voltage or current amplitude of the currently applied AC signal and return to step 812;

[0325] Step 840: Determine whether the temperatures of the electrode units 33 in the non-overtemperature region do not exceed the second preset temperature t2. If the temperatures of the electrode units 33 in the non-overtemperature region do not exceed the second preset temperature t2, execute step 841. If any of the temperatures of the electrode units 33 in the non-overtemperature region exceeds the second preset temperature t2, execute step 842.

[0326] Step 841: Continue applying the AC signal to each electrode unit 33 in the non-overtemperature area in a manner that maintains the voltage or current amplitude of the currently applied AC signal unchanged and return to step 812;

[0327] Step 842: Determine whether the temperatures of the electrode units 33 in the non-overtemperature region do not exceed the third preset temperature t3. If the temperatures of the electrode units 33 in the non-overtemperature region do not exceed the third preset temperature t3, execute step 843. If any of the temperatures of the electrode units 33 in the non-overtemperature region exceeds the third preset temperature t3, execute step 844.

[0328] Step 843: Continue applying the AC signal to each electrode unit 33 in the non-overtemperature area by reducing the voltage or current amplitude of the currently applied AC signal and return to step 812;

[0329] Step 844: Determine whether the temperatures of the electrode units 33 in the non-overtemperature region do not exceed the preset temperature threshold t0. If the temperatures of the electrode units 33 in the non-overtemperature region do not exceed the preset temperature threshold t0, execute step 845. If any of the temperatures of the electrode units 33 in the non-overtemperature region exceeds the preset temperature threshold t0, return to step 821.

[0330] Step 845 : Continue applying the AC signal to each electrode unit 33 in the non-overtemperature area in a manner of further reducing the voltage or current amplitude of the currently applied AC signal and return to step 812 .

[0331] The process of combining and controlling the grounding switch 54 and the bidirectional switch 55 electrically connected to the corresponding electrode sheet 13 in step 811 to apply an AC signal to each electrode unit 33 of the electrode sheet is as follows:

[0332] Disconnect all grounding switches 54 electrically connected to the corresponding electrode sheets 13, and simultaneously switch all bidirectional switches 55 electrically connected to the corresponding electrode sheets 13 to one end that applies an AC signal to each electrode unit 33; or

[0333] Disconnect all grounding switches 54 electrically connected to the corresponding electrode sheet 13, and simultaneously switch all bidirectional switches 55 electrically connected to the corresponding electrode sheet 13 to one end that electrically connects each electrode unit 33 to the AC signal line 57; or

[0334] All grounding switches 54 electrically connected to the corresponding electrode sheets 13 are disconnected, and at the same time, all bidirectional switches 55 electrically connected to the corresponding electrode sheets 13 are switched to their respective signal input terminals 2 .

[0335] The process of obtaining the temperature of each electrode unit 33 of the electrode sheet 13 in steps 812, 824, and 835 is specifically as follows:

[0336] Controlling the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch all ends from the end where the AC signal is applied to each electrode unit 33 to the end where the temperature of each electrode unit 33 is collected, and sequentially closing the grounding switch 54 electrically connected to the electrode unit 33 of the electrode sheet 13 in a time-division manner to obtain the temperature of each electrode unit 33 of the electrode sheet 13; or

[0337] Controlling the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch all signal input terminals 2 for applying an AC signal to each electrode unit 33 to its signal acquisition terminal 1, and sequentially closing the grounding switches 54 electrically connected to the electrode units 33 of the electrode sheet 13 in a time-division manner to obtain the temperature of each electrode unit 33 of the electrode sheet 13; or

[0338] Controlling the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch the electrode sheet 13 from being electrically connected to the AC signal line 57 to being electrically connected to the corresponding analog-to-digital converter 53, and sequentially closing the grounding switch 54 electrically connected to each electrode unit 33 of the electrode sheet 13 in a time-division manner to obtain the temperature of each electrode unit 33 of the electrode sheet 13; or

[0339] The bidirectional switching switch 55 electrically connected to the electrode sheet 13 is controlled to switch each electrode unit 33 of the electrode sheet 13 from transmitting an AC signal to transmitting a DC signal or a temperature detection signal, and the grounding switch 54 electrically connected to each electrode unit 33 of the electrode sheet 13 is closed in sequence in a time-sharing manner to obtain the temperature of each electrode unit 33 of the electrode sheet 13.

[0340] The first preset temperature in steps 813, 825, 828, 836, and 838 is 40°C to 40.3°C, preferably 40.2°C. The second preset temperature in steps 815, 830, and 840 is 40.4°C to 40.6°C, preferably 40.5°C. The third preset temperature in steps 817, 832, and 842 is 40.7°C to 40.9°C, preferably 40.8°C. The preset temperature threshold in steps 819 and 844 is 41°C to 41.5°C, preferably 41°C. The preset quantity threshold in step 822 is preferably 2.

[0341] The process of continuing to apply the AC signal in steps 814, 816, 818, 820, 829, 831, 833, 834, 839, 841, 843, and 845 is specifically as follows:

[0342] disconnecting the grounding switch 54 electrically connected to the electrode unit 33 to which the AC signal needs to be continuously applied, and simultaneously controlling the bidirectional switch 55 electrically connected to the electrode unit 33 to which the AC signal needs to be continuously applied to connect the AC signal transmission path electrically connected to the electrode unit 33 to which the AC signal needs to be continuously applied, thereby continuing to apply the AC signal to the electrode unit 33 to which the AC signal needs to be continuously applied; or

[0343] Disconnect the grounding switch 54 electrically connected to the electrode unit 33 to which the AC signal needs to be continuously applied, and at the same time control the bidirectional switch 55 electrically connected to the electrode unit 33 to which the AC signal needs to be continuously applied to switch from its respective signal acquisition end 1 to its respective signal input end 2 so as to continue to apply the AC signal to the electrode unit 33 to which the AC signal needs to be continuously applied; or

[0344] Disconnect the grounding switch 54 electrically connected to the electrode unit 33 to which the AC signal needs to be continuously applied, and simultaneously control the signal input terminals 2 of the bidirectional switches 55 electrically connected to the electrode unit 33 to which the AC signal needs to be continuously applied so that the AC signal continues to be applied to the electrode unit 33; or

[0345] Disconnect the grounding switch 54 electrically connected to the electrode unit 33 to which the AC signal needs to be continuously applied, and simultaneously control the bidirectional switch 55 electrically connected to the electrode unit 33 to which the AC signal needs to be continuously applied so that the respective signal input terminals 2 are closed and the signal acquisition terminals 1 are disconnected, thereby continuing to apply the AC signal to the electrode unit 33 to which the AC signal needs to be continuously applied; or

[0346] Disconnect the grounding switch 54 electrically connected to the electrode unit 33 to which the AC signal needs to continue to be applied, and at the same time control the bidirectional switching switch 55 electrically connected to the electrode unit 33 to which the AC signal needs to continue to be applied so that the electrode unit 33 to which the AC signal needs to continue to be applied switches from transmitting the temperature detection signal to applying the AC signal.

[0347] The method of increasing the voltage or current amplitude of the currently applied AC signal in step 814, step 829, and step 839 is to continue applying the AC signal by boosting the currently applied AC signal with a DC voltage amplitude increment of 0.03V per second and then continuing to apply the AC signal.

[0348] Continuing to apply the AC signal in a manner of reducing the voltage or current amplitude of the currently applied AC signal as described in step 818, step 820, step 833, step 834, step 843 and step 845 is specifically continuing to apply the AC signal in a manner of 5V less than the voltage amplitude of the currently applied AC signal and for 3 minutes.

[0349] The process of stopping applying the AC signal to each electrode unit 33 of the electrode sheet 13 in step 823 is specifically as follows:

[0350] Control the bidirectional switch 55 electrically connected to the electrode sheet 13 to disconnect the electrical connection between each electrode unit 33 of the electrode sheet 13 and the AC signal line 57; or

[0351] Control the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch from the end where the AC signal is applied to each electrode unit 33 to the end where the temperature is collected by each electrode unit 33; or

[0352] Control the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch all the signal input terminals 2 for applying AC signals to the electrode units 33 to the signal collection terminals 1 thereof; or

[0353] Controlling the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch the electrode sheet 13 from electrically connecting each electrode unit 33 thereof to the AC signal line 57 to electrically connecting each electrode unit 33 to the corresponding analog-to-digital converter 53; or

[0354] The bidirectional switch 55 electrically connected to the electrode sheet 13 is controlled to switch each electrode unit 33 of the electrode sheet 13 from transmitting an AC signal to transmitting a DC signal or a temperature detection signal.

[0355] The process of stopping applying the AC signal to each electrode unit 33 in the over-temperature area in step 827 is specifically as follows:

[0356] Control the bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature area to disconnect the electrical connection between each electrode unit 33 in the over-temperature area and the AC signal line 57; or

[0357] Control the bidirectional switches 55 electrically connected to the electrode units 33 in the over-temperature zone to switch all ends thereof from applying an AC signal to the electrode units 33 in the over-temperature zone to collecting temperature from the electrode units 33 in the over-temperature zone; or

[0358] Control the bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature area to switch all signal input terminals 2 for applying AC signals to each electrode unit 33 in the over-temperature area to their signal collection terminals 1; or

[0359] Controlling the bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature region to switch each electrode unit 33 in the over-temperature region from being electrically connected to the AC signal line 57 to being electrically connected to the corresponding analog-to-digital converter 53; or

[0360] The bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature area is controlled to switch each electrode unit 33 in the over-temperature area from transmitting an AC signal to transmitting a DC signal or a temperature detection signal.

[0361] When the tumor electric field therapy system 100 is in a standby state before starting work, no AC signal is applied to the electrode unit 33. The first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls the bidirectional switch 55 (55-1 to 55-5) to switch to the signal acquisition terminal 1, and the grounding switches 54 (54-1 to 54-4) are turned on in sequence. The analog-to-digital converter 52 receives the temperature detection signal of the temperature sensor 34 corresponding to each row of electrode units 33 (33-1 to 33-20) in sequence.

[0362] When the grounding switch 54-1 is turned on, the grounding switches (54-2, 54-3, 54-4) are all turned off, and the bidirectional switches (55-1 to 55-5) are all placed at the signal acquisition terminal 1, the analog-to-digital converter 52 receives the temperature detection signals of the temperature sensors 34 corresponding to the electrode units (33-1 to 33-5);

[0363] When the grounding switch 54-2 is turned on, the grounding switches (54-1, 54-3, 54-4) are all turned off, and the bidirectional switches (55-1 to 55-5) are all placed at the signal acquisition terminal 1, the analog-to-digital converter 52 receives the temperature detection signal of the temperature sensor 34 corresponding to the electrode unit (33-6 to 33-10);

[0364] When the grounding switch 54-3 is turned on, the grounding switches (54-1, 54-2, 54-4) are all turned off, and the bidirectional switches (55-1 to 55-5) are all placed at the signal acquisition terminal 1, the analog-to-digital converter 52 receives the temperature detection signal of the temperature sensor 34 corresponding to the electrode unit (33-11 to 33-15);

[0365] When the grounding switch 54-4 is turned on, the grounding switches (54-1, 54-2, 54-3) are all turned off, and the bidirectional switches (55-1 to 55-5) are all placed at the signal acquisition end 1, the analog-to-digital converter 52 receives the temperature detection signal of the temperature sensor 34 corresponding to the electrode unit (33-16 to 33-20).

[0366] The first controller 51 receives the temperature detection signal of the temperature sensor 34 corresponding to each electrode unit 33 (33-1 to 33-20) through the analog-to-digital converter 52, and transmits it to the AC signal generator 39 of the electric field generator 30 through the first communication unit 56 and the second communication unit 38, and then controls or adjusts the AC signal applied to each electrode unit 33 through the second controller 37.

[0367] While various operations are depicted in the drawings as following a particular order, this should not be understood as requiring that these operations be performed in the particular order shown or in sequential order, nor should it be understood that all illustrated operations must be performed to achieve desirable results.

[0368] An embodiment of the present application further provides a computer-readable storage medium on which an electrode sheet temperature detection program is stored. When the electrode sheet temperature detection program is executed by a controller, the aforementioned electrode sheet temperature detection method is implemented.

[0369] The embodiment of the present application also provides an adapter 20 for a tumor electric field therapy system 100, comprising a memory (not shown), a first controller 51, and an electrode sheet temperature detection program stored in the memory (not shown) and executable on the first controller 51. When the first controller 51 executes the electrode sheet temperature detection program, the aforementioned electrode sheet temperature detection method is implemented.

[0370] An embodiment of the present application also provides an electric field generator 30 for a tumor electric field therapy system 100, comprising a memory (not shown), a second controller 37, and an electrode sheet temperature detection program stored in the memory (not shown) and executable on the second controller 37. When the second controller 37 executes the electrode sheet temperature detection program, the aforementioned electrode sheet temperature detection method is implemented.

[0371] An embodiment of the present application further provides a computer-readable storage medium on which an electrode sheet qualification detection program is stored. When the electrode sheet qualification detection program is executed by a controller, the aforementioned electrode sheet qualification detection method is implemented.

[0372] The embodiment of the present application also provides an adapter 20 for a tumor electric field therapy system 100, comprising a memory (not shown), a first controller 51, and an electrode sheet qualification detection program stored in the memory (not shown) and executable on the first controller 51. When the first controller 51 executes the electrode sheet qualification detection program, the aforementioned electrode sheet qualification detection method is implemented.

[0373] An embodiment of the present application also provides an electric field generator 30 for a tumor electric field therapy system 100, comprising a memory (not shown), a second controller 37, and an electrode sheet qualification detection program stored in the memory (not shown) and executable on the second controller 37. When the second controller 37 executes the electrode sheet qualification detection program, the aforementioned electrode sheet qualification detection method is implemented.

[0374] The embodiment of the present application also provides a system for detecting an electrode sheet for tumor electric field therapy, which includes the aforementioned electrode sheet 13 and can detect or determine whether the electrode sheet is qualified according to the aforementioned electrode sheet detection method.

[0375] The electrode sheet qualification detection system for tumor electric field therapy of the embodiment of the present application may also include the above-mentioned adapter 20, on which an electrode sheet qualification detection program is stored. When the first controller 51 of the adapter 20 executes the electrode sheet qualification detection program, it detects or judges whether the electrode sheet is qualified according to the above-mentioned electrode sheet qualification detection method.

[0376] The electrode sheet qualification detection system for tumor electric field therapy in an embodiment of the present application may also include the above-mentioned electric field generator 30, on which an electrode sheet qualification detection program is stored. When the second controller 37 of the electric field generator 30 executes the electrode sheet qualification detection program, it detects or judges whether the electrode sheet is qualified according to the above-mentioned electrode sheet qualification detection method.

[0377] An embodiment of the present application further provides a computer-readable storage medium on which an electrode sheet replacement detection program is stored. When the electrode sheet replacement detection program is executed by a controller, the aforementioned electrode sheet replacement detection method is implemented.

[0378] The embodiment of the present application also provides an adapter 20 for a tumor electric field therapy system 100, comprising a memory (not shown), a first controller 51, and an electrode replacement detection program stored in the memory (not shown) and executable on the first controller 51. When the first controller 51 executes the electrode replacement detection program, the aforementioned electrode replacement detection method is implemented.

[0379] An embodiment of the present application also provides an electric field generator 30 for a tumor electric field therapy system 100, comprising a memory (not shown), a second controller 37, and an electrode replacement detection program stored in the memory (not shown) and executable on the second controller 37. When the second controller 37 executes the electrode replacement detection program, the aforementioned electrode replacement detection method is implemented.

[0380] The embodiment of the present application also provides an electrode sheet replacement detection system for tumor electric field therapy, which includes the aforementioned electrode sheet 13 and can detect or determine whether the electrode sheet needs to be replaced according to the aforementioned electrode sheet replacement detection method.

[0381] The electrode replacement detection system for tumor electric field therapy of the embodiment of the present application may also include the above-mentioned adapter 20, on which an electrode replacement detection program is stored. When the first controller 51 of the adapter 20 executes the electrode replacement detection program, it detects or determines whether the electrode needs to be replaced according to the above-mentioned electrode replacement detection method.

[0382] The electrode replacement detection system for tumor electric field therapy in an embodiment of the present application may also include the above-mentioned electric field generator 30, on which an electrode replacement detection program is stored. When the second controller 37 of the electric field generator 30 executes the electrode replacement detection program, it detects or determines whether the electrode needs to be replaced according to the above-mentioned electrode replacement detection method.

[0383] An embodiment of the present application further provides a computer-readable storage medium on which an electrode sheet temperature anomaly detection program is stored. When the electrode sheet temperature anomaly detection program is executed by a controller, the aforementioned electrode sheet temperature anomaly detection method is implemented.

[0384] An embodiment of the present application also provides an adapter 20 for a tumor electric field therapy system 100, comprising a memory (not shown), a first controller 51, and an electrode sheet temperature anomaly detection program stored in the memory (not shown) and executable on the first controller 51. When the first controller 51 executes the electrode sheet temperature anomaly detection program, the aforementioned electrode sheet temperature anomaly detection method is implemented.

[0385] An embodiment of the present application also provides an electric field generator 30 for a tumor electric field therapy system 100, comprising a memory (not shown), a second controller 37, and an electrode sheet temperature anomaly detection program stored in the memory (not shown) and executable on the second controller 37. When the second controller 37 executes the electrode sheet temperature anomaly detection program, the aforementioned electrode sheet temperature anomaly detection method is implemented.

[0386] The embodiment of the present application also provides an electrode temperature anomaly detection system for tumor electric field therapy, which includes the aforementioned electrode 13 and can detect or determine whether the electrode temperature is abnormal according to the aforementioned electrode temperature anomaly detection method.

[0387] The electrode sheet temperature anomaly detection system for tumor electric field therapy of the embodiment of the present application may also include the above-mentioned adapter 20, on which an electrode sheet temperature anomaly detection program is stored. When the first controller 51 of the adapter 20 executes the electrode sheet temperature anomaly detection program, it detects or determines whether the electrode sheet temperature is abnormal according to the above-mentioned electrode sheet temperature anomaly detection method.

[0388] The electrode sheet temperature anomaly detection system for tumor electric field therapy in an embodiment of the present application may also include the above-mentioned electric field generator 30, on which an electrode sheet temperature anomaly detection program is stored. When the second controller 37 of the electric field generator 30 executes the electrode sheet temperature anomaly detection program, it detects or determines whether the electrode sheet temperature is abnormal according to the above-mentioned electrode sheet temperature anomaly detection method.

[0389] An embodiment of the present application also provides a computer-readable storage medium on which is stored an AC signal application control program for tumor electric field therapy. When the AC signal application control program for tumor electric field therapy is executed by a controller, the aforementioned AC signal application control method for tumor electric field therapy is implemented.

[0390] The embodiment of the present application also provides an adapter 20 for a tumor electric field therapy system 100, comprising a memory (not shown), a first controller 51, and an AC signal application control program for tumor electric field therapy stored in the memory (not shown) and executable on the first controller 51. When the first controller 51 executes the AC signal application control program for tumor electric field therapy, the aforementioned AC signal application control method for tumor electric field therapy is implemented.

[0391] The embodiment of the present application also provides an electric field generator 30 for a tumor electric field therapy system 100, comprising a memory (not shown), a second controller 37, and an AC signal application control program for tumor electric field therapy stored in the memory (not shown) and executable on the second controller 37. When the second controller 37 executes the AC signal application control program for tumor electric field therapy, the aforementioned AC signal application control method for tumor electric field therapy is implemented.

[0392] An embodiment of the present application further provides a computer-readable storage medium on which an electrode sheet type identification program is stored. When the electrode sheet type identification program is executed by a controller, the aforementioned electrode sheet type identification method is implemented.

[0393] An embodiment of the present application also provides an adapter 20 for a tumor electric field therapy system 100, comprising a memory (not shown), a first controller 51, and an electrode sheet type identification program stored in the memory (not shown) and executable on the first controller 51. When the first controller 51 executes the electrode sheet type identification program, the aforementioned electrode sheet type identification method is implemented.

[0394] An embodiment of the present application also provides an electric field generator 30 for a tumor electric field therapy system 100, comprising a memory (not shown), a second controller 37, and an electrode sheet type identification program stored in the memory (not shown) and executable on the second controller 37. When the second controller 37 executes the electrode sheet type identification program, the aforementioned electrode sheet type identification method is implemented.

[0395] The embodiment of the present application further provides an electrode sheet type identification system for tumor electric field therapy, which includes the aforementioned electrode sheet 13 and can identify the type of the electrode sheet according to the aforementioned electrode sheet type identification method.

[0396] The electrode sheet type identification system for tumor electric field therapy in an embodiment of the present application may also include the above-mentioned adapter 20, on which an electrode sheet type identification program is stored. When the first controller 51 of the adapter 20 executes the electrode sheet type identification program, the electrode sheet type is identified according to the above-mentioned electrode sheet type identification method.

[0397] The electrode sheet type identification system for tumor electric field therapy in an embodiment of the present application may also include the above-mentioned electric field generator 30, on which an electrode sheet type identification program is stored. When the second controller 37 of the electric field generator 30 executes the electrode sheet type identification program, the electrode sheet type is identified according to the above-mentioned electrode sheet type identification method.

[0398] An embodiment of the present application also provides a computer-readable storage medium on which a signal control program for tumor electric field therapy is stored. When the signal control program for tumor electric field therapy is executed by a controller, the aforementioned signal control method for tumor electric field therapy is implemented.

[0399] The embodiment of the present application also provides an adapter 20 for a tumor electric field therapy system 100, comprising a memory (not shown), a first controller 51, and a signal control program for tumor electric field therapy stored in the memory (not shown) and executable on the first controller 51. When the first controller 51 executes the signal control program for tumor electric field therapy, the aforementioned signal control method for tumor electric field therapy is implemented.

[0400] The embodiment of the present application also provides an electric field generator 30 for a tumor electric field therapy system 100, comprising a memory (not shown), a second controller 37, and a signal control program for tumor electric field therapy stored in the memory (not shown) and executable on the second controller 37. When the second controller 37 executes the signal control program for tumor electric field therapy, the aforementioned signal control method for tumor electric field therapy is implemented.

[0401] An embodiment of the present application also provides a computer-readable storage medium on which another signal control program for tumor electric field therapy is stored. When the signal control program for tumor electric field therapy is executed by a controller, the aforementioned signal control method for tumor electric field therapy is implemented.

[0402] The embodiment of the present application also provides an adapter 20 for a tumor electric field therapy system 100, comprising a memory (not shown), a first controller 51, and another signal control program for tumor electric field therapy stored in the memory (not shown) and executable on the first controller 51. When the first controller 51 executes the another signal control program for tumor electric field therapy, the aforementioned another signal control method for tumor electric field therapy is implemented.

[0403] An embodiment of the present application also provides an electric field generator 30 for a tumor electric field therapy system 100, comprising a memory (not shown), a second controller 37, and another signal control program for tumor electric field therapy stored in the memory (not shown) and executable on the second controller 37. When the second controller 37 executes the another signal control program for tumor electric field therapy, the aforementioned another signal control method for tumor electric field therapy is implemented.

[0404] An embodiment of the present application also provides a computer-readable storage medium on which an AC signal application program based on a temperature detection signal is stored. When the AC signal application program based on a temperature detection signal is executed by a controller, the aforementioned AC signal application method based on a temperature detection signal is implemented.

[0405] The embodiment of the present application also provides an adapter 20 for a tumor electric field therapy system 100, comprising a memory (not shown), a first controller 51, and an AC signal application program based on a temperature detection signal stored in the memory (not shown) and executable on the first controller 51. When the first controller 51 executes the AC signal application program based on a temperature detection signal, the aforementioned AC signal application method based on a temperature detection signal is implemented.

[0406] An embodiment of the present application also provides an electric field generator 30 for a tumor electric field therapy system 100, comprising a memory (not shown), a second controller 37, and an AC signal application program based on a temperature detection signal stored in the memory (not shown) and executable on the second controller 37. When the second controller 37 executes the AC signal application program based on the temperature detection signal, the aforementioned AC signal application method based on the temperature detection signal is implemented.

[0407] Computer-readable storage media includes volatile and nonvolatile, removable and non-removable media implemented by any method or technology for storage of information, such as computer-readable instructions, data structures, program modules, or other data. Computer-readable storage media include, but are not limited to, RAM, ROM, EEPROM, flash memory or other memory technology, CD-ROM, digital versatile disks (DVD), or other optical storage devices, magnetic cassettes, magnetic tape, magnetic disk storage devices or other magnetic storage devices, or any other non-transmission media that can be used to store information for access by a computer device.

[0408] An embodiment of the present application further provides a computer program product, comprising instructions, which, when executed by a controller, causes the controller to execute a method as in any of the above embodiments.

[0409] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present application, rather than to limit them. Although the present application has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or make equivalent replacements for some or all of the technical features therein. These modifications or replacements do not deviate the essence of the corresponding technical solutions from the scope of the technical solutions of the embodiments of the present application, and they should all be included in the scope of the claims and specification of the present application. In particular, as long as there is no structural conflict, the various technical features mentioned in the various embodiments can be combined in any way. The present application is not limited to the specific embodiments disclosed herein, but includes all technical solutions that fall within the scope of the claims.

Claims

1. An electrode sheet for tumor electrotherapy, characterized in that, Including: A plurality of electrode units, which are divided into a plurality of row groups and a plurality of column groups; And A flexible circuit board configured to have the plurality of electrode units spaced thereon, and a plurality of conductive traces are embedded therein, the plurality of conductive traces including: A plurality of ground lines, corresponding to the plurality of row groups one by one, and each ground line is configured to short-circuit and ground the electrode units in the corresponding row group, and A plurality of dual-purpose signal lines, corresponding to the plurality of column groups one by one, and each dual-purpose signal line is configured to be capable of transmitting an alternating current signal to each of the electrode units in the corresponding column group, and also capable of transmitting a direct current signal to each of the electrode units in the corresponding column group or transmitting a temperature detection signal detected by each of the electrode units in the corresponding column group.

2. The electrode sheet according to claim 1, wherein The number of the dual-purpose signal lines is related to the number of the column groups into which the electrode units are divided, and the number of the ground lines is related to the number of the row groups into which the electrode units are divided.

3. The electrode sheet according to claim 2, wherein, The number of the dual-purpose signal lines is not less than the number of the column groups into which the electrode units are divided.

4. The electrode sheet according to claim 3, wherein The number of the dual-purpose signal lines is equal to the number of the column groups into which the electrode units are divided.

5. The electrode sheet according to claim 2, characterized in that, The number of the ground lines is not less than the number of the row groups into which the electrode units are divided.

6. The electrode sheet according to claim 5, characterized in that, The number of the ground lines is equal to the number of the row groups into which the electrode units are divided.

7. The electrode sheet according to claim 1, wherein The total number of the conductive traces is equal to the sum of the number of the row groups and the number of the column groups into which the electrode units are divided.

8. The electrode sheet according to any one of claims 1 to 7, characterized in that, Each of the electrode units includes a dielectric element for transmitting an alternating current signal and a temperature sensor having a signal terminal and a ground terminal, and the temperature sensor is used to detect the temperature of the corresponding electrode unit.

9. The electrode sheet according to claim 8, wherein, The dielectric element of each of the electrode units is short-circuited with the signal terminal of the temperature sensor.

10. The electrode sheet according to claim 9, characterized in that, Each of the electrode units further includes a diode connected in series with the temperature sensor, and the temperature sensor is grounded through the diode connected in series therewith.

11. The electrode sheet according to claim 9, characterized in that, The dielectric elements of the plurality of electrode units in the same column group are respectively connected in parallel to the same dual-purpose signal line of the flexible circuit board, the dielectric elements of the plurality of electrode units in different column groups are respectively connected in parallel through different dual-purpose signal lines of the flexible circuit board, the dielectric elements of the plurality of electrode units in the same row group are respectively connected in parallel through different dual-purpose signal lines of the flexible circuit board, and the dielectric elements of the plurality of electrode units in different row groups and different column groups are respectively connected in parallel through different dual-purpose signal lines of the flexible circuit board.

12. The electrode sheet according to claim 9, wherein The dielectric elements of the plurality of electrode units in the same column group and the signal terminals of their respective temperature sensors are respectively connected in parallel through the same dual-purpose signal line of the flexible circuit board, and the dielectric elements of the plurality of electrode units in different column groups and the signal terminals of their respective temperature sensors are respectively connected in parallel through different dual-purpose signal lines of the flexible circuit board.

13. The electrode sheet according to claim 9, wherein, The ground terminals of the temperature sensors of multiple electrode units within the same row group are all short-circuited through the same ground wire of the flexible circuit board, and the ground terminals of the temperature sensors of multiple electrode units within the same column group are respectively connected in parallel through different ground wires of the flexible circuit board; the signal terminals of the temperature sensors of multiple electrode units within the same row group are respectively connected in parallel through different two-purpose signal wires of the flexible circuit board, and the signal terminals of the temperature sensors of multiple electrode units within the same column group are all short-circuited through the same two-purpose signal wire of the flexible circuit board.

14. The electrode sheet according to claim 9, characterized in that, The dielectric elements of multiple electrode units within the same row group are respectively connected in parallel through different two-purpose signal wires of the flexible circuit board, and the dielectric elements of multiple electrode units within the same column group are all short-circuited through the same two-purpose signal wire of the flexible circuit board.

15. The electrode sheet according to claim 1, characterized in that, The total number of the electrode units does not exceed 20.

16. The electrode sheet according to claim 15, characterized in that, The total number of the electrode units is 20, which are divided into 4 row groups, and the number of electrode units in each row group is 5; or divided into 5 column groups, and the number of electrode units in each column group is 4.

17. The electrode sheet according to claim 16, characterized in that, The flexible circuit board is internally embedded with 5 two-purpose signal wires and 4 ground wires.

18. The electrode sheet according to claim 1, wherein, When the temperature of the electrode unit is detected, only one of the multiple ground wires is conducting at the same time, and the rest of the multiple ground wires are disconnected, and all of the multiple two-purpose signal wires are conducting when the temperature of the electrode unit is detected.

19. The electrode sheet according to claim 1, characterized in that, When an alternating current signal is applied to the electrode unit, all or some of the multiple two-purpose signal wires are conducting, and all of the multiple ground wires are disconnected when an alternating current signal is applied to the electrode unit.

20. The electrode sheet according to claim 16, wherein It further includes a first cable electrically connected to the flexible circuit board.

21. The electrode sheet according to claim 20, characterized in that, The first cable has 9 core wires, and each core wire is respectively electrically connected to the multiple two-purpose signal wires and multiple ground wires embedded in the flexible circuit board in a one-to-one correspondence.

22. A tumor electrotherapy system, characterized in that, It includes at least a pair of electrode plates according to any one of claims 1-21.

23. The tumor electric field therapy system according to claim 22, wherein, It further includes: An electric field generator configured to provide an alternating current signal to multiple electrode units of the electrode plate via the two-purpose signal wire of the electrode plate; and An adapter connected between the electrode plate and the electric field generator, configured to transmit the alternating current signal generated by the electric field generator to the multiple two-purpose signal wires of the electrode plate, and further configured to receive the temperature detection signal output by the multiple two-purpose signal wires of the electrode plate.

24. The tumor electro-field therapy system according to claim 23, wherein The adapter includes: One AC signal wire configured to provide an alternating current signal to each electrode unit in the corresponding column group through multiple two-purpose signal wires.

25. The tumor electric field therapy system according to claim 24, wherein, The adapter further includes: Multiple groups of ground switches, each group of ground switches is electrically connected to a corresponding electrode plate and each includes multiple ground switches, and the multiple ground switches are respectively electrically connected to the multiple ground wires of the corresponding electrode plate and are configured to control the conduction or disconnection of the multiple ground wires.

26. The tumor electric field therapy system according to claim 25, wherein, The adapter further includes: Multiple groups of analog-to-digital converters are electrically connected to the multiplexed signal lines of the corresponding electrode plates respectively, and are configured to receive the temperature detection signals transmitted by the multiplexed signal lines of the corresponding electrode plates and convert the temperature detection signals from analog signals to digital signals. Wherein, each group of analog-to-digital converters includes a plurality of detection channels, and each detection channel is used to connect to a corresponding one of the multiplexed signal lines.

27. The tumor electric field treatment system according to claim 26, wherein, The adapter further includes: Multiple groups of bidirectional switches, which correspond to the multiple electrode plates one by one. Each group of bidirectional switches includes a plurality of bidirectional switches, and the plurality of bidirectional switches are electrically connected to the multiplexed signal lines of the corresponding electrode plates one by one; Wherein, each bidirectional switch further has a signal acquisition terminal 1 electrically connected to a corresponding detection channel in the corresponding analog-to-digital converter and a signal input terminal 2 electrically connected to the AC signal line.

28. The tumor electric field therapy system according to claim 27, wherein, The adapter further includes: A first controller, which is respectively connected to the multiple groups of grounding switches and the multiple groups of bidirectional switches, and is configured to: Control the opening and closing states of the multiple grounding switches in sequence and cyclically, so as to sequentially and separately conduct each of the multiple ground wires of the corresponding electrode plate; and Control the switching states of the multiple bidirectional switches, so that the bidirectional switch is placed at the signal acquisition terminal 1 to output a temperature detection signal, or the bidirectional switch is placed at the signal input terminal 2 to transmit an alternating current signal.

29. The tumor electric field therapy system according to claim 28, wherein The adapter further includes: A first communication unit, which is configured to acquire the digital signals output by the multiple groups of analog-to-digital converters and send the digital signals to the electric field generator.

30. The tumor electric field therapy system according to claim 29, wherein, The electric field generator is further configured to control or adjust the alternating current signals provided to the corresponding electrode units in the multiple electrode units of the corresponding electrode plate according to the received digital signals.

31. The tumor electro-field therapy system according to claim 29, wherein The first communication unit is controlled by the first controller and serially transmits the digital signals converted by the analog-to-digital converter.

32. The tumor electro-field therapy system according to claim 23, wherein It further includes: A second cable, which is configured to connect the adapter and the electric field generator.

33. A method for detecting the temperature of an electrode sheet, characterized in that, Applied to the electrode plate according to any one of claims 1-21 or applied to the tumor electric field treatment system according to any one of claims 22-32, the method includes the following steps: Fully conduct all the multiplexed signal lines corresponding to the multiple column groups of the corresponding electrode plate respectively; and Sequentially and separately conduct each of the multiple ground wires corresponding to the multiple row groups of the electrode plate in sequence to collect the temperature detection signals of each electrode unit in each row group of the electrode plate by the multiplexed signal lines row by row.

34. A method for detecting the qualification of an electrode sheet, characterized in that, Whether the electrode plate is qualified is judged according to the temperature detection signals of each electrode unit of the electrode plate obtained by the method according to claim 33.

35. The method according to claim 34, wherein The judgment of whether the electrode plate is qualified includes the following steps: Judge whether each electrode unit has an abnormality or a failure according to the temperature detection signals of each electrode unit of the obtained electrode plate; and Judge whether the electrode sheet is qualified according to whether there is any abnormality or failure in each of the electrode units.

36. The method according to claim 35, characterized in that, Whether the electrode sheet is qualified is judged by the following method: Judge that the electrode sheet is qualified when there is no abnormality or failure in each of the electrode units of the electrode sheet; or Judge that the electrode sheet is unqualified when there is an abnormality or failure in one of the electrode units of the electrode sheet.

37. A method for detecting electrode sheet replacement, characterized in that, Whether the electrode sheet needs to be replaced is Judged based on the temperature detection signals of each of the electrode units of the electrode sheet obtained by the method according to claim 33.

38. The method according to claim 37, wherein Whether the electrode sheet needs to be replaced is judged by the following steps: Judge whether there is any abnormality or failure in each electrode unit according to the obtained temperature detection signals of each electrode unit; and Judge whether the electrode sheet needs to be replaced according to whether there is any abnormality or failure in each electrode unit.

39. The method according to claim 38, wherein Judging whether the electrode sheet needs to be replaced according to whether there is any abnormality or failure in each electrode unit includes the following steps: Determine the number of electrode units with abnormalities or failures. Judge whether the number of electrode units with abnormalities or failures exceeds a preset threshold; And Determine whether the electrode sheet needs to be replaced according to the judgment result.

40. The method according to claim 39, wherein The judgment result includes that the number of electrode units with abnormalities or failures does not exceed the preset threshold and the number of electrode units with abnormalities or failures exceeds the preset threshold. Whether the electrode sheet needs to be replaced is judged by the following method: Judge that the electrode sheet does not need to be replaced when the number of electrode units with abnormalities or failures does not exceed the preset threshold; or Judge that the electrode sheet needs to be replaced when the number of electrode units with abnormalities or failures exceeds the preset threshold.

41. The method according to claim 40, wherein The preset threshold is 20% of the total number of all electrode units of the electrode sheet.

42. A method for detecting abnormal temperature of an electrode sheet, characterized in that, The abnormal temperature condition of the electrode sheet is judged based on the temperature detection signals of each of the electrode units of the electrode sheet obtained by the method according to claim 33 under the condition that the electrode sheet is determined to be qualified by the method according to any one of claims 34-36.

43. The method according to claim 42, characterized in that, The judgment of the abnormal temperature of the electrode sheet includes the following steps: Compare the obtained temperatures of each of the electrode units with a preset temperature threshold; and Judge whether the temperature of the electrode sheet is abnormal according to the comparison result.

44. The method according to claim 43, wherein The comparison result includes not exceeding the preset temperature threshold and exceeding the preset temperature threshold. Whether the temperature of the electrode sheet is abnormal is judged by the following method: Judge that the electrode sheet has an abnormal temperature when the temperature of one of the electrode units exceeds the preset temperature threshold; or Judge that the electrode sheet does not have an abnormal temperature when the temperatures of all electrode units do not exceed the preset temperature threshold.

45. The method according to claim 43 or 44, characterized in that, The preset temperature threshold is 40.5°C - 41.5°C.

46. The method according to claim 45, characterized in that, The preset temperature threshold is 41°C - 41.5°C.

47. The method according to claim 46, wherein The preset temperature threshold is 41°C.

48. A control method for applying an alternating current signal in tumor electric field therapy, characterized in that, Applied to the electrode sheet according to any one of claims 1-21 or applied to the tumor electric field treatment system according to any one of claims 22-32.

49. The method according to claim 48, wherein The alternating current signals applied to the respective electrode units of the electrode sheet are controlled or adjusted according to the temperature detection signals of the respective electrode units of the electrode sheet obtained by the method according to any one of claims 33 to 41 when it is determined according to the method described in any one of claims 37 to 41 that the electrode sheet does not need to be replaced.

50. The method according to claim 49, characterized in that, The control or adjustment of the alternating current signals applied to the respective electrode units of the electrode sheet includes: comparing the obtained temperatures of the respective electrode units with a preset temperature threshold; and controlling or adjusting the alternating current signals applied according to the comparison result.

51. The method according to claim 50, wherein, The control or adjustment of the alternating current signals applied to the respective electrode units of the electrode sheet according to the comparison result is completed by the following method: When the temperature detection signals of the respective electrode units of the obtained electrode sheet do not exceed the preset temperature threshold, continue to apply alternating current signals to the respective electrode units of the electrode sheet; or When there is a temperature detection signal among the temperature detection signals of the respective electrode units of the obtained electrode sheet that exceeds the preset temperature threshold, stop applying alternating current signals to the electrode units of the electrode sheet.

52. The method according to claim 51, wherein The stopping of applying alternating current signals to the electrode units of the electrode sheet includes stopping applying alternating current signals to all the electrode units of the electrode sheet, stopping applying alternating current signals to the electrode units of the electrode sheet whose temperature detection signals exceed the preset temperature threshold, and stopping applying alternating current signals to all the electrode units in the column where the electrode units of the electrode sheet whose temperature detection signals exceed the preset temperature threshold are located.

53. The method according to claim 52, characterized in that, When stopping applying alternating current signals to the electrode units of the electrode sheet whose temperature detection signals exceed the preset temperature threshold, the electrode units of the electrode sheet whose temperature detection signals do not exceed the preset temperature threshold continue to be applied with alternating current signals.

54. The method according to claim 52, characterized in that, When stopping applying alternating current signals to all the electrode units in the column where the electrode units of the electrode sheet whose temperature detection signals exceed the preset temperature threshold are located, all the electrode units of the electrode sheet whose temperature detection signals do not exceed the preset temperature threshold and are in a different column from the electrode units whose temperature detection signals exceed the preset temperature threshold continue to be applied with alternating current signals.

55. The method according to claim 51, wherein The comparison results include not exceeding the preset temperature threshold and exceeding the preset temperature threshold. The situation of not exceeding the preset temperature threshold includes being far lower than the preset temperature threshold and being close to the preset temperature threshold.

56. The method according to claim 55, wherein When the temperature detection signals of the respective electrode units of the electrode sheet do not exceed the preset temperature threshold, the alternating current signals are continued to be applied to the respective electrode units of the electrode sheet by the following method: When the temperature detection signal is far lower than the preset temperature threshold, continue to apply the alternating current signals to the respective electrode units of the electrode sheet by increasing the voltage or current amplitude of the alternating current signals currently applied to the respective electrode units of the electrode sheet or by keeping the voltage or current amplitude of the alternating current signals currently applied to the respective electrode units of the electrode sheet unchanged; or When the temperature detection signal approaches the preset temperature threshold, continue to apply an alternating current signal to each electrode unit of the electrode patch in a manner that keeps the voltage or current amplitude of the alternating current signal applied to each electrode unit of the electrode patch unchanged, or continue to apply an alternating current signal to each electrode unit of the electrode patch in a manner that reduces the voltage or current amplitude of the alternating current signal applied to each electrode unit of the electrode patch.

57. The method according to any one of claims 51 - 56, characterized in that, The preset temperature threshold is 40.5°C - 41.5°C.

58. The method according to claim 57, characterized in that, The preset temperature threshold is 41°C - 41.5°C.

59. The method according to claim 58, characterized in that, The preset temperature threshold is 41°C.

60. A signal control method for tumor electrotherapy, characterized in that, Applied to the electrode patch according to any one of claims 1-21 or applied to the tumor electric field therapy system according to any one of claims 21-32.

61. The method according to claim 60, characterized in that: The signal for tumor electric field therapy is realized by combining the control of the conduction and disconnection of multiple two-way signal lines respectively corresponding to each column group of the electrode patch and electrically connected to the electrode units of each column group, and multiple ground lines respectively corresponding to each row group of the electrode patch and electrically connected to the electrode units of each row group, and realizing the cyclic switching of each electrode unit of the electrode patch between applying an alternating current signal and collecting or transmitting a temperature detection signal through multiple two-way signal lines electrically connected to each electrode unit of the electrode patch.

62. The method according to claim 61, characterized in that, The process of making each electrode unit of the electrode patch apply an alternating current signal includes the following steps: disconnect multiple ground lines respectively corresponding to and electrically connected to each electrode unit of each row group of the electrode patch, and at the same time conduct multiple two-way signal lines respectively corresponding to and electrically connected to each electrode unit of each column group of the electrode patch so that the multiple two-way signal lines electrically connected to the electrode patch transmit an alternating current signal to each electrode unit.

63. The method according to claim 62, wherein The process of making each electrode unit of the electrode patch transmit a temperature detection signal includes the following steps: Conduct multiple two-way signal lines respectively corresponding to and electrically connected to each electrode unit of each column group of the electrode patch so that the multiple two-way signal lines electrically connected to the electrode patch transmit a direct current signal to each electrode unit; and Sequentially and time-divisionally conduct one of the multiple ground lines respectively corresponding to and electrically connected to each electrode unit of each row group of the electrode patch to complete the transmission of the temperature detection signal of each electrode unit in each row group of the electrode patch time-divisionally row by row through the multiple two-way signal lines electrically connected to the electrode patch.

64. The method according to claim 63, wherein The method further includes the steps: Determine the combined control mode of conduction or disconnection of multiple ground lines respectively corresponding to each row group of the electrode patch and multiple two-way signal lines respectively corresponding to each column group of the electrode patch according to the obtained temperature detection signals of each electrode unit; And Control the working state of each electrode unit of the electrode patch according to the determined combined control mode of conduction or disconnection of the multiple ground lines and multiple two-way signal lines.

65. The method according to claim 64, wherein The working state of each electrode unit of the electrode patch includes one of stopping applying an alternating current signal and continuing to collect a temperature detection signal and stopping collecting a temperature detection signal and continuing to apply an alternating current signal.

66. The method according to claim 65, wherein The continued application of the alternating current signal includes continuing to apply the alternating current signal in a manner of increasing the voltage or current amplitude of the currently applied alternating current signal, continuing to apply the alternating current signal in a manner of keeping the voltage or current amplitude of the currently applied alternating current signal unchanged, or continuing to apply the alternating current signal in a manner of decreasing the voltage or current amplitude of the currently applied alternating current signal, and is one of the three.

67. A method for identifying an electrode sheet type, characterized in that, Applied to the electrode sheet according to any one of claims 1-21 or applied to the tumor electric field treatment system according to any one of claims 22-32.

68. The method according to claim 67, wherein The type of the electrode sheet is identified according to the temperature detection signals of the respective electrode units of the electrode sheet obtained by the method according to claim 33 when the electrode sheet is determined to be qualified by the method according to any one of claims 34-36.

69. A computer-readable storage medium, characterized in that, Stored thereon is an electrode sheet temperature detection program, and when the electrode sheet temperature detection program is executed by a controller, the electrode sheet temperature detection method according to claim 33 is implemented; or Stored thereon is an electrode sheet qualification detection program, and when the electrode sheet qualification detection program is executed by a controller, the electrode sheet qualification detection method according to any one of claims 34-36 is implemented; or Stored thereon is an electrode sheet replacement detection program, and when the electrode sheet replacement detection program is executed by a controller, the electrode sheet replacement detection method according to any one of claims 37-41 is implemented; or Stored thereon is an electrode sheet temperature anomaly detection program, and when the electrode sheet temperature anomaly detection program is executed by a controller, the electrode sheet temperature anomaly detection method according to any one of claims 42-47 is implemented; or Stored thereon is an alternating current signal application control program for tumor electric field treatment, and when the alternating current signal application control program for tumor electric field treatment is executed by a controller, the alternating current signal application control method for tumor electric field treatment according to any one of claims 48-59 is implemented; or Stored thereon is a signal control program for tumor electric field treatment, and when the signal control program for tumor electric field treatment is executed by a controller, the signal control method for tumor electric field treatment according to any one of claims 60-66 is implemented; or Stored thereon is an electrode sheet type identification program, and when the electrode sheet type identification program is executed by a controller, the electrode sheet type identification method according to claim 67 or 68 is implemented.

70. An adapter for tumor electric field therapy, comprising a memory and a controller, characterized in that, The adapter further includes: An electrode sheet temperature detection program stored on a memory and operable on a controller, and when the controller executes the electrode sheet temperature detection program, the electrode sheet temperature detection method according to claim 33 is implemented; or An electrode sheet qualification detection program stored on a memory and operable on a controller, and when the controller executes the electrode sheet qualification detection program, the electrode sheet qualification detection method according to any one of claims 34-36 is implemented; or An electrode sheet replacement detection program stored on a memory and operable on a controller, and when the controller executes the electrode sheet replacement detection program, the electrode sheet replacement detection method according to any one of claims 37-41 is implemented; or An electrode sheet temperature anomaly detection program stored in a memory and executable on a controller, when the controller executes the electrode sheet temperature anomaly detection program, implementing the electrode sheet temperature anomaly detection method according to any one of claims 42 - 47; or An alternating current signal application control program for tumor electrotherapy stored in a memory and executable on a controller, when the controller executes the alternating current signal application control program for tumor electrotherapy, implementing the alternating current signal application control method for tumor electrotherapy according to any one of claims 48 - 59; or A signal control program for tumor electrotherapy stored in a memory and executable on a controller, when the controller executes the signal control program for tumor electrotherapy, implementing the signal control method for tumor electrotherapy according to any one of claims 60 - 66; or An electrode sheet type identification program stored in a memory and executable on a controller, when the controller executes the electrode sheet type identification program, implementing the electrode sheet type identification method according to claim 67 or 68.

71. An electric field generator for tumor electrotherapy, comprising a memory and a controller, characterized in that, The electric field generator further includes: An electrode sheet temperature detection program stored in a memory and executable on a controller, when the controller executes the electrode sheet temperature detection program, implementing the electrode sheet temperature detection method according to claim 33; or An electrode sheet qualification detection program stored in a memory and executable on a controller, when the controller executes the electrode sheet qualification detection program, implementing the electrode sheet qualification detection method according to any one of claims 34 - 36; or An electrode sheet replacement detection program stored in a memory and executable on a controller, when the controller executes the electrode sheet replacement detection program, implementing the electrode sheet replacement detection method according to any one of claims 37 - 41; or An electrode sheet temperature anomaly detection program stored in a memory and executable on a controller, when the controller executes the electrode sheet temperature anomaly detection program, implementing the electrode sheet temperature anomaly detection method according to any one of claims 42 - 47; or An alternating current signal application control program for tumor electrotherapy stored in a memory and executable on a controller, when the controller executes the alternating current signal application control program for tumor electrotherapy, implementing the alternating current signal application control method for tumor electrotherapy according to any one of claims 48 - 59; or A signal control program for tumor electrotherapy stored in a memory and executable on a controller, when the controller executes the signal control program for tumor electrotherapy, implementing the signal control method for tumor electrotherapy according to any one of claims 60 - 66; or An electrode sheet type identification program stored in a memory and executable on a controller, when the controller executes the electrode sheet type identification program, implementing the electrode sheet type identification method according to claim 67 or 68.

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