Measurement method, system, and related apparatus
By implanting electrode arrays under the skin, combined with microneedle sensors and array sensors, the problem of bulky electrocardiographs being unportable has been solved, enabling the measurement of electrocardiogram and physiological parameters anytime and anywhere, thus improving the efficiency of health monitoring.
Patent Information
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- HUAWEI TECH CO LTD
- Filing Date
- 2024-12-27
- Publication Date
- 2026-05-15
AI Technical Summary
Existing electrocardiographs are bulky and inconvenient for users to carry around, making it impossible to monitor electrocardiograms and measure physiological parameters anytime and anywhere.
The first and second electrode groups are implanted in the subcutaneous tissue. The electrocardiogram signals and physiological parameters, including blood glucose, blood ketones, blood lactate, and uric acid, are determined through the electrode groups. The electrode groups are arranged using microneedle sensors or array sensors, and signal processing is performed in conjunction with a microcontroller processing unit and an electrochemical circuit module.
It enables the measurement of electrocardiogram signals and various physiological parameters anytime and anywhere, improving the efficiency and portability of health monitoring.
Smart Images

Figure CN2024143450_15052026_PF_FP_ABST
Abstract
Description
A measurement method, system and related apparatus
[0001] This application claims priority to Chinese Patent Application No. 202311865433.9, filed on December 29, 2023, entitled "A Measurement Method, System and Related Apparatus", the entire contents of which are incorporated herein by reference. Technical Field
[0002] This application relates to the field of electronic technology, and in particular to a measurement method, system and related apparatus. Background Technology
[0003] With the continuous development of electronic technology, more and more electronic devices are equipped with health monitoring functions, allowing users to understand their own health status in real time. Electrocardiogram (ECG) monitoring is one of the important components of health monitoring functions.
[0004] An electrocardiograph (ECG) is a medical device that monitors the electrocardiogram (ECG). During monitoring, the ECG machine obtains the user's ECG by contacting multiple wet electrodes at different locations on the user's skin.
[0005] However, electrocardiographs are bulky and inconvenient for users to carry around, making it impossible for users to monitor their heart rate anytime and anywhere. Summary of the Invention
[0006] This application provides a measurement method, system, and related device that enables the measurement of electrocardiogram signals anytime and anywhere, and can also measure one or more physiological parameters, thereby improving the efficiency of health monitoring.
[0007] In a first aspect, this application provides a measurement method applied to a first electronic device, the first electronic device including a first electrode group and a second electrode group, the distance between the first electrode group and the second electrode group being greater than a first distance; when the first electrode group and the second electrode group are implanted in subcutaneous tissue, the method includes: determining a first physiological parameter through the first electrode group; and determining an electrocardiogram signal through the first electrode group and the second electrode group.
[0008] In this way, users' electrocardiogram signals can be measured anytime and anywhere, as well as physiological parameters such as blood sugar, blood ketones, blood lactate, and uric acid.
[0009] In one possible implementation, the first electrode group includes a first working electrode and a first pair of electrodes, and the second electrode group includes a second working electrode; the first pair of electrodes forms a circuit with the first working electrode; determining a first physiological parameter through the first electrode group specifically includes: determining the first physiological parameter through the first working electrode and the first pair of electrodes; determining an electrocardiogram (ECG) signal through the first electrode group and the second electrode group specifically includes: determining the ECG signal through the first working electrode and the second working electrode, or, determining the ECG signal through the first pair of electrodes and the second working electrode.
[0010] In this way, the first electrode group can form a two-electrode system through which the first physiological parameter can be measured. The first working electrode (or the first pair of electrodes) in the first electrode group and any one electrode in the second electrode group can be used as the left arm LA electrode and the right arm RA electrode, respectively, to measure electrocardiogram signals.
[0011] In one possible implementation, the first electrode group includes a first working electrode and a first pair of electrodes, and the second electrode group includes a second working electrode; the first pair of electrodes forms a circuit with the first working electrode; the first working electrode or the first pair of electrodes is connected to the right leg drive circuit; determining a first physiological parameter through the first electrode group specifically includes: determining the first physiological parameter through the first working electrode and the first pair of electrodes; determining an electrocardiogram signal through the first electrode group and the second electrode group specifically includes: determining the electrocardiogram signal through the first working electrode, the first pair of electrodes, and the second working electrode.
[0012] The electrode connected to the right leg drive circuit can serve as the right leg drive RLD electrode. The right leg drive circuit can be used to cancel common-mode signals.
[0013] In this way, the first electrode group can form a two-electrode system, through which the first physiological parameter can be measured. The first working electrode, the first pair of electrodes, and any one of the electrodes in the second electrode group can be used as the left arm LA electrode, the right leg drive RLD electrode, and the right arm RA electrode, respectively, to measure electrocardiogram signals.
[0014] In one possible implementation, the first electrode group includes a first working electrode, a first reference electrode, and a first pair of electrodes; the first reference electrode is used to control the voltage of the first working electrode, and the first pair of electrodes forms a circuit with the first working electrode; determining a first physiological parameter through the first electrode group specifically includes: generating a first current through the first working electrode; and determining the first physiological parameter based on the first current.
[0015] In this way, the first electrode group can form a three-electrode system, through which the first current is generated and conducted.
[0016] In one possible implementation, the second electrode assembly includes a second working electrode, a second reference electrode, and a second pair of electrodes; the second reference electrode is used to control the voltage of the second working electrode, and the second pair of electrodes is used to form a circuit with the second working electrode; the method further includes: generating a second current through the second working electrode; and determining a second physiological parameter based on the second current.
[0017] In this way, the second electrode group can form a three-electrode system, through which a second current is generated and conducted.
[0018] In one possible implementation, the electrocardiogram (ECG) signal is determined by a first electrode group and a second electrode group, specifically by determining the ECG signal by any one electrode in the first electrode group and any one electrode in the second electrode group.
[0019] The left and right arm electrodes can be selected from one electrode in the first electrode group and one electrode in the second electrode group, respectively. In this way, electrocardiogram signals can be measured using the left and right arm electrodes.
[0020] In one possible implementation, the electrocardiogram (ECG) signal is determined by a first electrode group and a second electrode group, specifically including: determining the ECG signal by any two electrodes in the first electrode group and any one electrode in the second electrode group; or, determining the ECG signal by any two electrodes in the first electrode group and any two electrodes in the second electrode group.
[0021] The left arm electrode and right arm electrode can be selected from one electrode in the first electrode group and one electrode in the second electrode group, respectively. The right leg drive electrode can be an electrode from either the first electrode group or the second electrode group. In this way, electrocardiogram (ECG) signals can be measured using the left arm electrode, right arm electrode, and right leg drive electrode. The right leg drive electrode is used to cancel common-mode signals through the right leg drive circuit.
[0022] In this way, the electrochemical electrodes in the first electrode group can be used to measure both the first physiological parameter and the electrocardiogram signal.
[0023] In one possible implementation, the electrocardiogram (ECG) signal is determined by any two electrodes in the first electrode group and any one electrode in the second electrode group. Specifically, when the first pair of electrodes is connected to the right leg drive circuit, the ECG signal is determined by the first pair of electrodes, the first working electrode, and the second reference electrode.
[0024] In one possible implementation, the electrocardiogram (ECG) signal is determined by any one electrode in the first electrode group and any two electrodes in the second electrode group. Specifically, when the second pair of electrodes is connected to the right leg drive circuit, the ECG signal is determined by the second pair of electrodes, the second working electrode, and the first reference electrode.
[0025] It should be noted that the above two implementation methods are just two examples. In this application, other electrodes in the first electrode group and the second electrode group can also be selected to measure electrocardiogram signals. This application does not limit this.
[0026] In one possible implementation, the first electrode group further includes a first ECG electrode and a second ECG electrode, and the second electrode group further includes a third ECG electrode. The second ECG electrode is connected to a right leg drive circuit. The ECG signal is determined by the first electrode group and the second electrode group, specifically by determining the ECG signal through the first ECG electrode, the second ECG electrode, and the third ECG electrode.
[0027] In this way, electrocardiogram (ECG) signals can be measured using individually set ECG electrodes.
[0028] In one possible implementation, the first electronic device further includes a first microneedle sensor and a second microneedle sensor, the first microneedle sensor including a first electrode group and the second microneedle sensor including a second electrode group.
[0029] Microneedle sensors can refer to sensors that resemble microneedles in shape, and multiple electrodes can be set inside a microneedle sensor.
[0030] In this way, the first electrode group and the second electrode group can be set in the microneedle sensor.
[0031] In one possible implementation, the first electronic device further includes a first array sensor and a second array sensor, the first array sensor including a first electrode group and the second array sensor including a second electrode group.
[0032] An array sensor can refer to a sensor that includes multiple electrodes arranged in an array. In one possible implementation, an array sensor can also consist of multiple electrodes arranged in an array.
[0033] In this way, the first electrode group and the second electrode group can be arranged in the array sensor in the form of arrays.
[0034] In one possible implementation, the first electronic device further includes a first microneedle sensor and a second array sensor, the first microneedle sensor including a first electrode group and the second array sensor including a second electrode group.
[0035] In this way, the first electrode group can be set in the microneedle sensor, and the second electrode group can be set in the array sensor in the form of an array.
[0036] In one possible implementation, before determining the first physiological parameter via the first electrode group, the method further includes: determining that a first condition is met, the first condition including any one or more of the following: receiving first information sent by a second electronic device, the first information being used to instruct the first electronic device to determine the first physiological parameter; detecting that the first electrode group and the second electrode group are implanted in subcutaneous tissue; detecting an abnormal electrocardiogram signal.
[0037] Thus, the first condition can be the trigger condition for measuring the first physiological parameter.
[0038] In one possible implementation, before determining the electrocardiogram (ECG) signal via the first electrode group and the second electrode group, the method further includes: determining that a second condition is met, the second condition including any one or more of the following: receiving second information sent by a second electronic device, the second information being used to instruct the first electronic device to determine the ECG signal; detecting that the first electrode group and the second electrode group are implanted in subcutaneous tissue; detecting that a first physiological parameter does not belong to a first interval.
[0039] Thus, the second condition can be the triggering condition for determining the electrocardiogram signal.
[0040] In one possible implementation, after determining the first physiological parameter through the first electrode group, the method further includes: outputting the first physiological parameter, or sending the first physiological parameter to a second electronic device.
[0041] In this way, the first physiological parameter can be output, or the first physiological parameter can be output through other electronic devices.
[0042] In one possible implementation, after determining the electrocardiogram (ECG) signal via the first and second electrode groups, the method further includes: outputting the ECG signal, or sending the ECG signal to a second electronic device.
[0043] In this way, ECG signals can be output, or ECG signals can be output through other electronic devices.
[0044] In one possible implementation, the first physiological parameter may include, but is not limited to, any one or more of the following: blood glucose, blood ketones, uric acid, blood lactate, etc.
[0045] Secondly, this application provides an electronic device, which is a first electronic device, including a first electrode group and a second electrode group, wherein the distance between the first electrode group and the second electrode group is greater than a first distance; the first electrode group is used to determine a first physiological parameter when the first electrode group is implanted in subcutaneous tissue; the second electrode group is used to determine a second physiological parameter when the second electrode group is implanted in subcutaneous tissue; the first electrode group and the second electrode group are also used to determine an electrocardiogram signal when the first electrode group and the second electrode group are implanted in subcutaneous tissue.
[0046] In one possible implementation, the first electrode group includes a first working electrode and a first pair of electrodes, and the second electrode group includes a second working electrode and a second pair of electrodes; the first pair of electrodes forms a circuit with the first working electrode, and the second pair of electrodes forms a circuit with the second working electrode; the first electrode group is used to determine a first physiological parameter when the first electrode group is implanted in subcutaneous tissue, specifically including: the first working electrode is used to determine the first physiological parameter when the first working electrode is implanted in subcutaneous tissue; the second electrode group is used to determine a second physiological parameter when the second electrode group is implanted in subcutaneous tissue, specifically including: the second working electrode is used to determine the second physiological parameter when the second working electrode is implanted in subcutaneous tissue; the first electrode group and the second electrode group are also used to determine an electrocardiogram (ECG) signal when the first electrode group and the second electrode group are implanted in subcutaneous tissue, specifically including: the first working electrode, the first pair of electrodes, and the second working electrode are also used to determine an ECG signal when the first working electrode, the first pair of electrodes, and the second working electrode are implanted in subcutaneous tissue.
[0047] In one possible implementation, the first electronic device further includes a microcontroller unit (MCU); the first electrode group includes a first working electrode, a first reference electrode, and a first pair of electrodes; the second electrode group includes a second working electrode, a second reference electrode, and a second pair of electrodes; the first electrode group is used to determine a first physiological parameter when the first electrode group is implanted in subcutaneous tissue, specifically including: the first working electrode is used to generate a first current when the first working electrode is implanted in subcutaneous tissue; the first reference electrode is used to control the voltage of the first working electrode; the first pair of electrodes is used to form a circuit with the first working electrode; the MCU is used to determine the first physiological parameter based on the first current; the second electrode group is used to determine a second physiological parameter when the second electrode group is implanted in subcutaneous tissue, specifically including: the second working electrode is used to generate a second current when the second working electrode is implanted in subcutaneous tissue; the second reference electrode is used to control the voltage of the second working electrode; the second pair of electrodes is used to form a circuit with the second working electrode; the MCU is used to determine the second physiological parameter based on the second current.
[0048] In one possible implementation, the first electrode group and the second electrode group are further used to determine the electrocardiogram (ECG) signal when the first electrode group and the second electrode group are implanted in subcutaneous tissue. Specifically, any two electrodes in the first electrode group and any one electrode in the second electrode group are used to determine the ECG signal when the first electrode group and the second electrode group are implanted in subcutaneous tissue; or, any two electrodes in the first electrode group and the second electrode group are used to determine the ECG signal when the first electrode group and the second electrode group are implanted in subcutaneous tissue.
[0049] The left arm electrode and right arm electrode can be selected from one electrode in the first electrode group and one electrode in the second electrode group, respectively. The right leg drive electrode can be an electrode from either the first electrode group or the second electrode group. In this way, electrocardiogram (ECG) signals can be measured using the left arm electrode, right arm electrode, and right leg drive electrode. The right leg drive electrode is used to cancel common-mode signals through the right leg drive circuit.
[0050] In one possible implementation, any two electrodes in the first electrode group and any one electrode in the second electrode group are used to determine the electrocardiogram signal when the first electrode group and the second electrode group are implanted in subcutaneous tissue. Specifically, when the first pair of electrodes is connected to the right leg drive circuit, the first pair of electrodes, the first working electrode, and the second reference electrode are used to determine the electrocardiogram signal when the first electrode group and the second electrode group are implanted in subcutaneous tissue.
[0051] In one possible implementation, any one electrode in the first electrode group and any two electrodes in the second electrode group are used to determine the electrocardiogram signal when the first electrode group and the second electrode group are implanted in subcutaneous tissue. Specifically, when the second pair of electrodes is connected to the right leg drive circuit, the second pair of electrodes, the second working electrode, and the first reference electrode are used to determine the electrocardiogram signal when the first electrode group and the second electrode group are implanted in subcutaneous tissue.
[0052] It should be noted that the above two implementation methods are just two examples. In this application, other electrodes in the first electrode group and the second electrode group can also be selected to measure electrocardiogram signals. This application does not limit this.
[0053] In one possible implementation, the first electrode group further includes a first ECG electrode and a second ECG electrode, and the second electrode group further includes a third ECG electrode. The second ECG electrode is connected to a right leg drive circuit. The first electrode group and the second electrode group are also used to determine the ECG signal when the first electrode group and the second electrode group are implanted in subcutaneous tissue. Specifically, the first ECG electrode, the second ECG electrode and the third ECG electrode are used to determine the ECG signal when the first electrode group and the second electrode group are implanted in subcutaneous tissue.
[0054] In one possible implementation, the first electronic device further includes a first microneedle sensor and a second microneedle sensor, the first microneedle sensor including a first electrode group and the second microneedle sensor including a second electrode group.
[0055] In one possible implementation, the first electronic device further includes a first array sensor and a second array sensor, the first array sensor including a first electrode group and the second array sensor including a second electrode group.
[0056] In one possible implementation, the first electronic device further includes a first microneedle sensor and a second array sensor, the first microneedle sensor including a first electrode group and the second array sensor including a second electrode group.
[0057] In one possible implementation, the first electronic device further includes a communication module; the communication module is used to send a first physiological parameter to the second electronic device; the communication module is also used to send an electrocardiogram signal to the second electronic device.
[0058] In one possible implementation, the first electronic device further includes an output module; the output module is used to output the first physiological parameter; the output module is also used to output the electrocardiogram signal.
[0059] Thirdly, this application provides a measurement circuit, including a first electrode group, a second electrode group, a first electrochemical circuit module, a second electrochemical circuit module, an electrocardiogram (ECG) circuit module, and a microcontroller unit (MCU); the first electrode group is connected to the first electrochemical circuit module and also to the ECG circuit module; the second electrode group is connected to the second electrochemical circuit module and also to the ECG circuit module; the MCU is connected to the first electrochemical circuit module, the second electrochemical circuit module, and the ECG circuit module; the first electrode group is used to generate a first current signal; the first electrode group is also used to transmit the first current signal to the first electrochemical circuit module; the first electrochemical circuit module is used to determine a second current signal based on the first current signal; the first electrochemical circuit module is also used to... A second current signal is transmitted to an MCU; the MCU is used to determine a first physiological parameter based on the second current signal; a second electrode group is used to generate a third current signal; the second electrode group is also used to transmit the third current signal to a second electrochemical circuit module; the second electrochemical circuit module is used to determine a fourth current signal based on the third current signal; the second electrochemical circuit module is also used to transmit the fourth current signal to the MCU; the MCU is used to determine a second physiological parameter based on the fourth current signal; a first electrode group and a second electrode group are used to acquire a first electrocardiogram (ECG) signal; the first electrode group and the second electrode group are also used to transmit the first ECG signal to an ECG circuit module; the ECG circuit module is used to determine a second ECG signal based on the first ECG signal; the ECG circuit module is also used to transmit the second ECG signal to the MCU.
[0060] In one possible implementation, the first electrode group includes a first working electrode, a first reference electrode, and a first pair of electrodes; the first electrochemical circuit module includes a first potentiostat circuit and a first transimpedance circuit; the first potentiostat circuit is used to control the voltage of the first working electrode and the first reference electrode; the first transimpedance circuit is used to amplify the first current signal; the first electrode group is connected to the first electrochemical circuit module, specifically including: the first working electrode, the first reference electrode, and the first pair of electrodes are connected to the first potentiostat circuit; the first working electrode and the first transimpedance circuit are connected.
[0061] In one possible implementation, the second electrode group includes a second working electrode, a second reference electrode, and a second pair of electrodes; the second electrochemical circuit module includes a second potentiostat circuit and a second transimpedance circuit; the second potentiostat circuit is used to control the voltage of the second working electrode and the second reference electrode; the second transimpedance circuit is used to amplify the third current signal; the second electrode group is connected to the second electrochemical circuit module, specifically including: the second working electrode, the second reference electrode, and the second pair of electrodes are connected to the second potentiostat circuit, and the second working electrode is connected to the second transimpedance circuit.
[0062] In one possible implementation, the ECG circuit module includes a right leg drive circuit, an amplifier circuit, and a filter circuit, with the amplifier circuit and filter circuit connected together. The right leg drive circuit is used to cancel common-mode signals, the amplifier circuit is used to amplify the first ECG signal, and the filter circuit is used for filtering. A first electrode group is connected to the ECG circuit module, specifically including: a first working electrode connected to the amplifier circuit, and a first pair of electrodes connected to the right leg drive circuit. A second electrode group is connected to the ECG circuit module, specifically including: a second reference electrode connected to the amplifier circuit. The first electrode group and the second electrode group are used to acquire the first ECG signal, specifically including: a first working electrode and a second reference electrode. The reference electrode is used to acquire a first electrocardiogram (ECG) signal; the first electrode group and the second electrode group are also used to transmit the first ECG signal to the ECG circuit module, specifically including: the first working electrode and the second reference electrode are used to transmit the first ECG signal to the amplification circuit; the ECG circuit module is used to determine a second ECG signal based on the first ECG signal, specifically including: the amplification circuit is used to amplify the first ECG signal and transmit it to the filtering circuit; the filtering circuit is used to determine the second ECG signal based on the amplified first ECG signal; the ECG circuit module is also used to transmit the second ECG signal to the MCU, specifically including: the filtering circuit is also used to transmit the second ECG signal to the MCU.
[0063] In one possible implementation, the first electrode group further includes a first ECG electrode and a second ECG electrode, and the second electrode group further includes a third ECG electrode. The ECG circuit module includes a right leg drive circuit, an amplifier circuit, and a filter circuit, with the amplifier circuit and the filter circuit connected. The right leg drive circuit is used to cancel common-mode signals, the amplifier circuit is used to amplify the first ECG signal, and the filter circuit is used for filtering. The first electrode group is connected to the ECG circuit module, specifically including: the first ECG electrode is connected to the amplifier circuit, and the second ECG electrode is connected to the right leg drive circuit; the second electrode group is connected to the ECG circuit module, specifically including: the third ECG electrode... The electrodes are connected to the amplifier circuit module; the first electrode group and the second electrode group are used to conduct the ECG signal to the ECG circuit module, specifically including: the first ECG electrode and the third ECG electrode are used to conduct the ECG signal to the amplifier circuit; the ECG circuit module is used to determine the second ECG signal based on the first ECG signal, specifically including: the amplifier circuit is used to amplify the first ECG signal and conduct it to the filter circuit; the filter circuit is used to determine the second ECG signal based on the amplified first ECG signal; the ECG circuit module is also used to conduct the second ECG signal to the MCU, specifically including: the filter circuit is also used to conduct the second ECG signal to the MCU.
[0064] Fourthly, this application provides a measurement circuit, including a first electrode group, a second electrode group, a first switching switch, a first electrochemical circuit module, an electrocardiogram (ECG) circuit module, and a microcontroller unit (MCU). The first switching switch includes a first set of input ports, a second set of input ports, and a first set of output ports. The first switching switch is used to connect either the first set of input ports or the second set of input ports. The first electrode group is connected to the first set of input ports and to the ECG circuit module. The second electrode group is connected to the second set of input ports and to the ECG circuit module. The first set of output ports is connected to the first electrochemical circuit module. The MCU is connected to both the first electrochemical circuit module and the ECG circuit module. The first electrode group is used to generate a first current signal. The first electrode group is also used to transmit the first current signal to the first switching switch. The first switching switch is used to transmit the first current signal to the first electrochemical circuit module when the first set of input ports is connected. The first electrochemical circuit module is used for... A second current signal is determined based on a first current signal; the first electrochemical circuit module is also used to send the second current signal to the MCU; the MCU is used to determine a first physiological parameter based on the second current signal; a second electrode group is used to generate a third current signal; the second electrode group is also used to conduct the third current signal to a first switching switch; the first switching switch is used to conduct the third current signal to the first electrochemical circuit module when the second input port is turned on; the first electrochemical circuit module is also used to determine a fourth current signal based on the third current signal; the first electrochemical circuit module is also used to conduct the fourth current signal to the MCU; the MCU is used to determine a second physiological parameter based on the fourth current signal; the first electrode group and the second electrode group are used to acquire a first electrocardiogram (ECG) signal; the first electrode group and the second electrode group are also used to conduct the first ECG signal to the ECG circuit module; the ECG circuit module is used to determine a second ECG signal based on the first ECG signal; the ECG circuit module is also used to conduct the second ECG signal to the MCU.
[0065] In one possible implementation, the first electrode group includes a first working electrode, a first reference electrode, and a first pair of electrodes; the first set of input ports includes a first input port, a second input port, and a third input port; the second electrode group includes a second working electrode, a second reference electrode, and a second pair of electrodes; the second set of input ports includes a fourth input port, a fifth input port, and a sixth input port; the first working electrode is connected to the first input port, the first reference electrode is connected to the second input port, and the first pair of electrodes is connected to the third input port; the second working electrode is connected to the fourth input port, the second reference electrode is connected to the fifth input port, and the second pair of electrodes is connected to the sixth input port.
[0066] In one possible implementation, the first set of output ports includes a first output port, a second output port, and a third output port; the first switch is used to connect the first set of input ports, specifically including: the first output port is used to connect the first input port, the second output port is used to connect the second input port, and the third output port is used to connect the third input port; the first switch is used to connect the second set of input ports, specifically including: the first output port is used to connect the fourth input port, the second output port is used to connect the fifth input port, and the third output port is used to connect the sixth input port.
[0067] In one possible implementation, the first electrochemical circuit module includes a first potentiostat circuit and a first transimpedance circuit; the first potentiostat circuit is used to control the voltage of the first working electrode and the first reference electrode; the first transimpedance circuit is used to amplify the first current signal; a first set of output ports is connected to the first electrochemical circuit module, specifically including: a first output port, a second output port and a third output port connected to the first potentiostat circuit; the first output port is connected to the first transimpedance circuit.
[0068] It is understood that the measurement circuit provided in the fourth aspect can be combined with any possible implementation of the measurement circuit provided in the third aspect above.
[0069] Fifthly, this application provides a measurement circuit, including a first electrode group, a second electrode group, a second switching switch, a third switching switch, a fourth switching switch, a first electrochemical circuit module, an electrocardiogram (ECG) circuit module, and a microcontroller unit (MCU). The second switching switch includes a third set of input ports, a fourth set of input ports, and a second set of output ports. The second switching switch is used to connect either the third or fourth set of input ports. The first electrode group is connected to the third set of input ports and is also connected to the ECG circuit module. The second electrode group is connected to the fourth set of input ports and is also connected to the ECG circuit module. The second set of output ports is connected to the third switching switch. A switch and a fourth switch are connected to the first electrochemical circuit module. The second output port is connected to the ECG circuit module via a third switch and a fourth switch. The third and fourth switches are used to control the second set of output ports to connect to either the first electrochemical circuit module or the ECG circuit module. The MCU is connected to both the first electrochemical circuit module and the ECG circuit module. The first electrode group is used to generate a first current signal. The first electrode group is also used to transmit the first current signal to the second switch. The second switch is used when the second switch connects to the third set of input ports, and the third and fourth switches control the second set of output ports to connect to the first electrochemical circuit. When the module is in operation, a first current signal is transmitted to the first electrochemical circuit module; the first electrochemical circuit module is used to determine a second current signal based on the first current signal; the first electrochemical circuit module is also used to send the second current signal to the MCU; the MCU is used to determine a first physiological parameter based on the second current signal; the second electrode group is used to generate a third current signal; the second electrode group is also used to transmit the third current signal to the first switching switch; the first switching switch is used to transmit the third current signal to the first electrochemical circuit module when the second switching switch is connected to the fourth input port, and the third switching switch and the fourth switching switch control the second output port to connect to the first electrochemical circuit module. The circuit module includes: a first electrochemical circuit module for determining a fourth current signal based on a third current signal; a first electrochemical circuit module for transmitting the fourth current signal to an MCU; an MCU for determining a second physiological parameter based on the fourth current signal; a first electrode group and a second electrode group for acquiring a first electrocardiogram (ECG) signal; the first electrode group and the second electrode group for transmitting the first ECG signal to the ECG circuit module when the third and fourth switching switches control the second group output port to connect to the ECG circuit module; the ECG circuit module for determining a second ECG signal based on the first ECG signal; and the ECG circuit module for transmitting the second ECG signal to the MCU.
[0070] It is understood that the measurement circuit provided in the fifth aspect can be combined with any of the possible implementations of the measurement circuits provided in the third and fourth aspects above.
[0071] In a sixth aspect, this application provides a chip system applied to a first electronic device, the chip system comprising: a processing circuit and an interface circuit, the interface circuit being used to receive code instructions and transmit them to the processing circuit, the processing circuit being used to execute the code instructions to cause the chip system to perform the measurement method in any possible implementation of any of the above aspects.
[0072] In a seventh aspect, embodiments of this application provide a readable storage medium including instructions that, when executed on a first electronic device, cause the first electronic device to perform the measurement method in any possible implementation of any of the above aspects.
[0073] Eighthly, embodiments of this application provide a computer program product that, when run on a first electronic device, causes the first electronic device to execute the measurement method in any possible implementation of any of the above aspects.
[0074] The beneficial effects of aspects two through eight can be referenced from the beneficial effects of aspect one above. Attached Figure Description
[0075] Figure 1A is a schematic diagram of a scenario for measuring physiological parameters using a three-electrode system according to an embodiment of this application;
[0076] Figure 1B is a schematic diagram of the system architecture of a measurement system 10 provided in an embodiment of this application;
[0077] Figure 2A is a schematic diagram of the hardware structure of an electronic device 100 provided in an embodiment of this application;
[0078] Figure 2B is a schematic diagram of the hardware structure of an electronic device 200 provided in an embodiment of this application;
[0079] Figure 3A is a schematic diagram of the device configuration of an electronic device 200 provided in an embodiment of this application;
[0080] Figure 3B is a schematic diagram of the internal structure of an electronic device 200 provided in an embodiment of this application;
[0081] Figure 3C is a schematic diagram of the electrode distribution on a microneedle sensor 303 provided in an embodiment of this application;
[0082] Figure 3D is a schematic diagram of the device configuration of another electronic device 200 provided in an embodiment of this application;
[0083] Figure 3E is a schematic diagram of the internal structure of another electronic device 200 provided in an embodiment of this application;
[0084] Figures 4A and 4B are schematic diagrams showing the connection relationship between the two circuit modules and the processor provided in the embodiments of this application;
[0085] Figures 4C-4J are schematic diagrams of a set of measurement circuits provided in the embodiments of this application;
[0086] Figure 5A is a flowchart illustrating a measurement method provided in an embodiment of this application;
[0087] Figure 5B is a waveform diagram of an electrocardiogram signal provided in an embodiment of this application;
[0088] Figure 5C shows an electrocardiogram provided in an embodiment of this application;
[0089] Figure 6 is a flowchart illustrating another measurement method provided in an embodiment of this application;
[0090] Figures 7A-7F are schematic diagrams of the output interface of a set of physiological parameters provided in the embodiments of this application;
[0091] Figures 7G-7J are schematic diagrams of a set of electrocardiogram signal output interfaces provided in the embodiments of this application;
[0092] Figures 7K-7L are schematic diagrams of the interface for triggering electrocardiogram monitoring when a set of physiological parameters are abnormal, as provided in the embodiments of this application.
[0093] Figures 7M-7N are schematic diagrams of a set of interfaces for performing micro-physical examination functions provided in the embodiments of this application;
[0094] Figure 8 is a schematic diagram of the functional modules of an electronic device 200 provided in an embodiment of this application;
[0095] Figure 9 is a schematic diagram of the functional modules of a measurement system 10 provided in an embodiment of this application;
[0096] Figure 10 is a schematic diagram of the physical entity of an electronic device 300 provided in an embodiment of this application;
[0097] Figure 11 is a flowchart illustrating a measurement method provided in an embodiment of this application. Detailed Implementation
[0098] The technical solutions in the embodiments of this application will be clearly and thoroughly described below with reference to the accompanying drawings. In the description of the embodiments of this application, unless otherwise stated, " / " means "or," for example, A / B can mean A or B; the word "and / or" in the text is merely a description of the relationship between related objects, indicating that three relationships can exist. For example, A and / or B can represent: A existing alone, A and B existing simultaneously, and B existing alone. Furthermore, in the description of the embodiments of this application, "multiple" refers to two or more than two.
[0099] Hereinafter, the terms "first" and "second" are used for descriptive purposes only and should not be construed as implying or suggesting relative importance or implicitly indicating the number of indicated technical features. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature, and in the description of the embodiments of this application, unless otherwise stated, "multiple" means two or more.
[0100] The term "user interface (UI)" used in the following embodiments of this application refers to the medium interface through which an application or operating system interacts and exchanges information with the user. It realizes the conversion between the internal form of information and the form that the user can accept. The user interface is source code written in a specific computer language such as Java or Extensible Markup Language (XML). The interface source code is parsed and rendered on the electronic device, ultimately presenting content that the user can recognize. A common form of user interface is the graphical user interface (GUI), which refers to a user interface related to computer operation displayed graphically. It can be visible interface elements such as text, icons, buttons, menus, tabs, text boxes, dialog boxes, status bars, navigation bars, and widgets displayed on the screen of an electronic device.
[0101] The following describes some terms used in the embodiments of this application.
[0102] Electrocardiogram (ECG): An electrocardiogram is a curve showing the changes in bioelectric potential generated during a heartbeat. It is an important physiological indicator that characterizes the occurrence, propagation, and response of electrical excitation in the heart.
[0103] Electrocardiogram (ECG): During each cardiac cycle, the heart is successively excited by the pacemaker, atria, and ventricles, accompanied by changes in bioelectricity, which are called ECG. The heart pumps blood rhythmically, and its contraction and relaxation rhythm is controlled by cardiac electrical activity. Under normal circumstances, the sinoatrial node regularly sends impulses, which, through a special conduction system, generate electrical impulses throughout the myocardium. The electric field generated by these impulses is distributed throughout the body, and the resulting tiny currents are conducted through body tissues to different locations, causing different potentials in different parts of the body. Therefore, by placing electrodes at different locations on the body surface, the potential difference at different locations can be measured, thus determining the electrocardiogram (ECG).
[0104] Electrode lead system: The electrode lead system is used to indicate the number and arrangement of multiple electrodes used to measure electrocardiogram (ECG). Electrode lead systems can include, but are not limited to, any one or more of the following: the international standard twelve-lead system, the bipolar lead system, etc.
[0105] The international standard 12-lead system: In the international standard 12-lead system, ten electrodes are placed on the body surface. These ten electrodes are located in the left arm (LA), right arm (RA), left leg (LL), right leg (RL), and the remaining six electrodes are located on the chest. The electrode on the right leg can serve as a reference electrode, while the remaining nine electrodes can be used as ECG detection electrodes to measure the electrocardiogram (ECG) signals on the body surface (e.g., the potential difference between different parts of the body surface) and determine the ECG based on the measured signals.
[0106] Bipolar lead system: A bipolar lead system can include three electrodes: a left arm (LA) electrode, a right arm (RA) electrode, and a right leg (RL) electrode. Typically, the left arm electrode is placed on the left arm, the right arm electrode on the right arm, and the right leg electrode on the right leg. It should be noted that these three electrodes can also be placed in other locations on the body. The bipolar lead system acquires the electrocardiogram (ECG) signal on the body surface by measuring the potential difference between the two limbs and determines the ECG based on the measured signal. The left and right arm electrodes are used to acquire the ECG signal on the body surface (e.g., the potential difference between the left and right arms), while the right leg electrode serves as a reference electrode.
[0107] Common-mode interference: During ECG measurement, the right leg can be considered grounded, and the LA and RA electrodes measure ground-based ECG signals. However, the human body has grounding impedance, which introduces common-mode interference, generating common-mode signals. The right leg drive (RLD) circuit can cancel these common-mode signals. The RLD circuit can be connected to the RL electrode to eliminate signals and improve measurement accuracy.
[0108] Right Leg Driven Electrode: The right leg driven (RLD) electrode refers to an RL electrode connected to an RLD circuit. The RLD electrode, LA electrode, and RA electrode can constitute a bipolar lead system for measuring electrocardiogram (ECG) signals. In the embodiments of this application, the electrode used to measure ECG signals can also be referred to as an ECG electrode. When a bipolar lead system is used to measure ECG signals, the ECG electrode may include an LA electrode, a RA electrode, and an RLD electrode.
[0109] Blood sugar: Blood sugar refers to glucose in the blood. Glucose is an important component of the human body and a vital source of energy. A normal human body needs a significant amount of glucose daily to provide energy for the normal functioning of various tissues and organs. Blood sugar must be maintained within a certain range to meet the needs of the body's organs and tissues. Excessively high blood sugar can easily lead to diabetes, while excessively low blood sugar can cause insufficient energy for the body's organs, resulting in serious consequences.
[0110] Blood ketones: Blood ketones refer to the level of ketone bodies in the blood. Muscles and fat produce ketone bodies through exercise metabolism, and these ketone bodies enter the bloodstream. Blood ketone levels within the normal range do not have a negative impact on the body. When blood ketone levels are too high (e.g., above a certain value), the body is at risk of acidosis.
[0111] Blood lactate: Blood lactate refers to the concentration of lactic acid in the blood. Blood lactate is an intermediate product of glucose metabolism in the body, mainly produced by red blood cells, skeletal muscle, and brain tissue. The concentration of lactate in the blood depends primarily on the synthesis rate and metabolic rate of the liver and kidneys. Lactate monitoring refers to measuring the concentration of lactate in the blood, which helps determine whether a user's liver and kidney function are normal.
[0112] Uric acid: Uric acid is the end product of purine metabolism, specifically trioxypurine, and its alcohol form is weakly acidic. The human body contains uric acid, which is excreted through urine. An imbalance between the production and excretion of uric acid in the body can easily lead to elevated blood uric acid levels, thus causing disease. Uric acid is mainly produced in the liver, and most of it is filtered by the glomeruli and excreted in the urine. Therefore, uric acid monitoring helps determine whether a user's liver and kidney functions are normal.
[0113] Electrochemical electrodes: Electrochemical electrodes react with specific substances to generate current or voltage. In the embodiments of this application, electrochemical electrodes can be used to measure one or more physiological parameters, such as blood glucose, blood ketones, uric acid, and blood lactate. Electrochemical electrodes can include various types according to their functions: working electrode, counter electrode, and reference electrode. Multiple electrochemical electrodes with different functions can form an electrochemical system to measure physiological parameters. Common electrochemical systems include two-electrode systems and three-electrode systems.
[0114] Two-electrode system: A two-electrode system may include a working electrode and a counter electrode, or a working electrode and a reference electrode. In a two-electrode system, the working electrode can be used to carry out the reaction under study, and the counter electrode (or reference electrode) can form a circuit with the working electrode and control the voltage of the working electrode.
[0115] Three-electrode system: A three-electrode system may include a working electrode, a reference electrode, and a counter electrode. In a three-electrode system, the working electrode can be used to carry out the reaction under study, the counter electrode can form a circuit with the working electrode, and the reference electrode can control the voltage of the working electrode. Specific examples of the three-electrode system can be found in the embodiment shown in Figure 1A below.
[0116] Continuous glucose monitoring (CGM) devices are electronic devices used to measure blood glucose levels. A CGM device may include an electrochemical electrode containing a glucose enzyme (such as glucose oxidase). After the CGM device is implanted subcutaneously, the glucose enzyme in the electrochemical electrode reacts with glucose in the tissue fluid, generating an electric current. The CGM device measures the current generated by the reaction between the glucose enzyme and glucose, and based on the magnitude of the current, determines the glucose concentration in the user's tissue fluid, and then determines the glucose concentration in the user's blood, i.e., the user's blood glucose level.
[0117] Enzymes: Enzymes are proteins or ribonucleic acid (RNA) produced by living cells that exhibit high specificity and catalytic efficiency towards their substrates. The ability of an enzyme to catalyze a chemical reaction is called enzyme activity (also known as enzyme power). Enzyme activity is temperature-dependent. Different types of enzymes have different optimal temperatures; the enzyme's activity is highest and its catalytic ability is strongest when the temperature of its environment is at its optimal range.
[0118] For example, Figure 1A shows a schematic diagram of a scenario for measuring physiological parameters using a three-electrode system according to an embodiment of this application.
[0119] As shown in Figure 1A, a three-electrode system can include a working electrode, a reference electrode, and a counter electrode. The working electrode (WE), also called the research electrode, is the electrode used to carry out the reaction under study. Taking an electrochemical electrode for measuring blood glucose as an example, the working electrode can contain a substance capable of reacting with glucose (e.g., glucose oxidase), and can be used to generate a reaction current. The counter electrode (CE), also called the auxiliary electrode, can form a circuit with the working electrode to ensure that the current flows through the working electrode, guaranteeing that the reaction under study occurs at the working electrode. The reference electrode (RE) is an electrode with a known potential that is close to ideally non-polarized. Almost no current flows through the reference electrode, which is used to control the voltage of the working electrode.
[0120] When the working electrode, reference electrode, and counter electrode are implanted in subcutaneous tissue, the working electrode can react with the target substance (such as glucose, ketone bodies, uric acid, lactic acid, etc.) to generate a reaction current. By measuring the magnitude of this reaction current, the values of physiological parameters can be determined.
[0121] The following describes the system architecture of a measurement system 10 provided in an embodiment of this application.
[0122] As shown in Figure 1B, the measurement system 10 may include electronic device 100 and electronic device 200. A communication connection may be established between electronic device 100 and electronic device 200. This communication connection can be a wired connection or a wireless connection. The wireless communication connection may be constructed by electronic device 100 and electronic device 200 using any of the following wireless communication technologies: wireless local area networks (WLAN) (such as wireless fidelity (Wi-Fi) networks), Bluetooth (BT), global navigation satellite system (GNSS), frequency modulation (FM), near field communication (NFC), infrared (IR), NearLink, and intrabody communication (IBC).
[0123] In some embodiments, when monitoring condition 3 is detected, electronic device 100 may send information 3 to electronic device 200, which requests electronic device 200 to send physiological data 1 to electronic device 100. Physiological data 1 is used to determine the user's physiological parameters 1 (e.g., blood glucose, blood ketones, uric acid, blood lactate, etc.). In some embodiments, electronic device 100 may also send information 4 to electronic device 200 when monitoring condition 4 is detected, which requests electronic device 200 to send an electrocardiogram (ECG) signal to electronic device 100. The specific content of monitoring conditions 3 and 4 can be found in the relevant descriptions in the embodiments shown in Figure 6 below, and will not be detailed here. In some embodiments, electronic device 100 may also send information 5 to electronic device 200, which requests electronic device 200 to send an ECG signal and physiological data 1 to electronic device 100.
[0124] Electronic device 100 can receive physiological data sent by electronic device 200, and determine and output the user's physiological parameters based on the physiological data. Electronic device 100 can also receive and output electrocardiogram (ECG) signals sent by electronic device 200.
[0125] The electronic device 200 may include multiple electrochemical electrodes, which can react with specific chemical substances to generate a reaction current. The electronic device 200 can acquire the user's physiological data, which can be used to determine one or more physiological parameters such as blood glucose, blood ketones, uric acid, and blood lactate. The electronic device 200 can also acquire the user's electrocardiogram (ECG) signals through multiple ECG electrodes. It should be noted that in some embodiments, the multiple ECG electrodes may be multiple electrodes from the aforementioned multiple electrochemical electrodes, or they may be electrodes different from the aforementioned multiple electrochemical electrodes. In other embodiments, one or more of the multiple ECG electrodes may be the same as one or more of the aforementioned multiple electrochemical electrodes.
[0126] In some embodiments, electronic device 200 may receive and respond to information 3 to send the user's physiological data to electronic device 100. Electronic device 200 may also receive and respond to information 4 to send an electrocardiogram (ECG) signal to electronic device 100.
[0127] In other embodiments, the electronic device 200 may also determine and output the user's physiological parameter 1 (e.g., send physiological parameter 1 to the electronic device 100) when monitoring condition 1 is detected to be met. The electronic device 200 may also acquire and output the user's electrocardiogram (ECG) signal (e.g., send ECG signal to the electronic device 100) when monitoring condition 2 is detected to be met. The specific contents of monitoring condition 1 and monitoring condition 2 can also be referred to the relevant description in the embodiment shown in Figure 5A below, and will not be detailed here.
[0128] In this application embodiment, electronic device 100 can be a wearable device such as a watch or bracelet, or a mobile phone, display screen, tablet computer, or computer. Electronic device 200 can be used to measure one or more physiological parameters, and can also be used to measure electrocardiogram signals. This application does not limit the device type of electronic device 100 and electronic device 200.
[0129] It is understood that the measurement system 10 shown in Figure 1B is just an example. In the embodiments of this application, the measurement system 10 may also include more or fewer electronic devices than the above embodiments, or electronic devices with different device forms than the above embodiments. This application does not limit this.
[0130] The hardware structure of an electronic device 100 provided in the embodiments of this application is described below.
[0131] Figure 2A shows a schematic diagram of the hardware structure of an electronic device 100 provided in an embodiment of this application.
[0132] Electronic device 100 may be a mobile phone, tablet computer, desktop computer, laptop computer, handheld computer, notebook computer, ultra-mobile personal computer (UMPC), netbook, as well as cellular phone, personal digital assistant (PDA), augmented reality (AR) device, virtual reality (VR) device, artificial intelligence (AI) device, wearable device, in-vehicle device, smart home device and / or smart city device. The embodiments of this application do not impose any special restrictions on the specific type of electronic device.
[0133] Electronic device 100 may include a processor 110, internal memory 121, charging management module 140, power management module 141, battery 142, sensor module 180, and display screen 194, etc. Optionally, electronic device 100 may also include one or more of the following: wireless communication module 160, audio module 170, buttons 190, motor 191, indicator 192, photoplethysmography (PPG) module 195, and airbag, etc. The audio module 170 may include one or more of the following: speaker 170A, receiver 170B, and microphone 170C. The sensor module 180 may include a touch sensor 180K.
[0134] It is understood that the structures illustrated in the embodiments of the present invention do not constitute a specific limitation on the electronic device 100. In other embodiments of this application, the electronic device 100 may include more or fewer components than illustrated, or combine some components, or split some components, or have different component arrangements. The illustrated components may be implemented in hardware, software, or a combination of software and hardware.
[0135] Processor 110 may include one or more processing units, such as application processor (AP), modem processor, graphics processing unit (GPU), image signal processor (ISP), controller, video codec, digital signal processor (DSP), baseband processor, and / or neural network processing unit (NPU). These different processing units may be independent devices or integrated into one or more processors.
[0136] The controller can generate operation control signals based on the instruction opcode and timing signals to complete the control of instruction fetching and execution.
[0137] The processor 110 may also include a memory for storing instructions and data. In some embodiments, the memory in the processor 110 is a cache memory. This memory can store instructions or data that the processor 110 has just used or that are used repeatedly. If the processor 110 needs to use the instruction or data again, it can retrieve it directly from the memory. This avoids repeated accesses, reduces the waiting time of the processor 110, and thus improves the efficiency of the system.
[0138] In some embodiments, the processor 110 may include one or more interfaces. Interfaces may include an inter-integrated circuit (I2C) interface, an inter-integrated circuit sound (I2S) interface, a pulse code modulation (PCM) interface, a universal asynchronous receiver / transmitter (UART) interface, a mobile industry processor interface (MIPI), a general-purpose input / output (GPIO) interface, a subscriber identity module (SIM) interface, and / or a universal serial bus (USB) interface, etc.
[0139] The charging management module 140 receives charging input from a charger. The charger can be a wireless charger or a wired charger. In some wired charging embodiments, the charging management module 140 can receive charging input from a wired charger. In some wireless charging embodiments, the charging management module 140 can receive wireless charging input through the wireless charging coil of the electronic device 100. While charging the battery 142, the charging management module 140 can also supply power to the electronic device through the power management module 141.
[0140] The power management module 141 connects the battery 142, the charging management module 140, and the processor 110. The power management module 141 receives input from the battery 142 and / or the charging management module 140, providing power to the processor 110, internal memory 121, display screen 194, and wireless communication module 160, etc. The power management module 141 can also monitor parameters such as battery capacity, battery cycle count, and battery health status (leakage current, impedance). In some other embodiments, the power management module 141 may also be located within the processor 110. In other embodiments, the power management module 141 and the charging management module 140 may be located in the same device.
[0141] The wireless communication module 160 can provide solutions for wireless communication applied to the electronic device 100, including wireless local area networks (WLANs) (such as wireless fidelity (Wi-Fi) networks), Bluetooth (BT), global navigation satellite system (GNSS), frequency modulation (FM), near field communication (NFC), infrared (IR), NearLink, and intrabody communication (IBC). For example, when two electronic devices communicate using an IBC solution, both devices have at least one electrode that contacts the skin, through which they send and receive information via the human body. The wireless communication module 160 can be one or more devices integrating at least one communication processing module.
[0142] Electronic device 100 implements display functions through a GPU, a display screen 194, and an application processor. The GPU is a microprocessor for image processing, connected to the display screen 194 and the application processor. The GPU is used to perform mathematical and geometric calculations and for graphics rendering. Processor 110 may include one or more GPUs, which execute program instructions to generate or modify display information.
[0143] Display screen 194 is used to display images, videos, etc. Display screen 194 includes a display panel. The display panel can be a liquid crystal display (LCD), or it can be manufactured using organic light-emitting diodes (OLEDs), active-matrix organic light-emitting diodes (AMOLEDs), flexible light-emitting diodes (FLEDs), minimized LEDs, microLEDs, micro-OLEDs, quantum dot light-emitting diodes (QLEDs), etc. In some embodiments, electronic device 100 may include one or N displays 194, where N is a positive integer greater than 1.
[0144] Internal memory 121 may include one or more random access memory (RAM) and one or more non-volatile memory (NVM). The RAM can be directly read and written by the processor 110 and can be used to store executable programs (e.g., machine instructions) of the operating system or other running programs, as well as user and application data. The NVM can also store executable programs and user and application data, and can be pre-loaded into the RAM for direct read and write operations by the processor 110.
[0145] Electronic device 100 can implement audio functions, such as music playback and recording, through audio module 170, speaker 170A, receiver 170B, microphone 170C, and application processor.
[0146] The audio module 170 is used to convert digital audio information into analog audio signals for output, and also to convert analog audio input into digital audio signals. The audio module 170 can also be used for encoding and decoding audio signals. In some embodiments, the audio module 170 may be located in the processor 110, or some functional modules of the audio module 170 may be located in the processor 110.
[0147] The speaker 170A, also known as a "loudspeaker," is used to convert audio electrical signals into sound signals. The electronic device 100 can listen to music or make hands-free calls through the speaker 170A.
[0148] The receiver 170B, also known as the "earpiece," is used to convert audio electrical signals into sound signals. When the electronic device 100 answers a telephone call or voice message, the receiver 170B can be brought close to the ear to listen to the voice.
[0149] Microphone 170C, also known as a "microphone" or "voice transducer," is used to convert sound signals into electrical signals. When making a phone call or sending a voice message, the user can speak by bringing their mouth close to microphone 170C, inputting the sound signal into microphone 170C. Electronic device 100 may have at least one microphone 170C. In some embodiments, electronic device 100 may have two microphones 170C, which, in addition to collecting sound signals, can also perform noise reduction. In other embodiments, electronic device 100 may also have three, four, or more microphones 170C, which can collect sound signals, reduce noise, identify the sound source, and perform directional recording, etc.
[0150] Touch sensor 180K, also known as a "touch device," can be located on display screen 194. The touch sensor 180K and display screen 194 together form a touchscreen, also known as a "touchscreen." Touch sensor 180K detects touch operations applied to or near it. The touch sensor can transmit the detected touch operation to the application processor to determine the type of touch event. Visual output related to the touch operation can be provided through display screen 194. In other embodiments, touch sensor 180K may also be located on the surface of electronic device 100, in a different position than display screen 194.
[0151] Buttons 190 include a power button, volume buttons, etc. Buttons 190 can be mechanical buttons or touch-sensitive buttons. Electronic device 100 can receive button input and generate key signal inputs related to user settings and function control of electronic device 100.
[0152] Motor 191 can generate vibration alerts. Motor 191 can be used for incoming call vibration alerts or for touch vibration feedback. For example, different vibration feedback effects can correspond to touch operations performed on different applications (such as taking photos, playing audio, etc.). Motor 191 can also correspond to different vibration feedback effects for touch operations performed on different areas of the display screen 194. Different application scenarios (such as time reminders, receiving messages, alarm clocks, games, etc.) can also correspond to different vibration feedback effects. The touch vibration feedback effect can also be customized.
[0153] Indicator 192 can be an indicator light, used to indicate charging status, power changes, or to indicate messages, missed calls, notifications, etc.
[0154] PPG module 195 is an optional device. PPG module 195 may include a transmitter and a receiver. The transmitter can be used to emit infrared light or green light, and the receiver can be used to receive infrared light or green light reflected from biological tissues (such as skin, blood, etc.). In some embodiments, PPG module 195 can measure one or more of the following physiological information: blood oxygen concentration, heart rate, blood pressure, respiratory rate, etc.
[0155] In some embodiments, the sensor module 180 of the electronic device 100 may further include one or more of the following sensors: an accelerometer, a barometric pressure sensor, a temperature sensor, a gyroscope sensor, etc.
[0156] An accelerometer can detect the magnitude of acceleration of an electronic device 100 in various directions (typically three axes). When the electronic device 100 is stationary, it can detect the magnitude and direction of gravity. It can also be used to identify the posture of the electronic device and is applied to applications such as screen orientation switching and pedometers.
[0157] A barometric pressure sensor can be used to measure air pressure, and in some embodiments, it can also be used to measure water pressure.
[0158] Temperature sensors can be used to measure a user's body temperature or the temperature of the user's environment.
[0159] A gyroscope sensor can be used to determine the motion attitude of an electronic device 100. In some embodiments, the angular velocity of the electronic device 100 about three axes (i.e., the x, y, and z axes) can be determined by the gyroscope sensor.
[0160] In some embodiments, the electronic device 100 may further include an airbag, which can be used to measure blood pressure.
[0161] Figure 2B is a schematic diagram of the hardware structure of an electronic device 200 provided in an embodiment of this application.
[0162] As shown in Figure 2B, the electronic device 200 includes a processor 201, a memory 202, a sensor 203, a wireless communication module 204, a power supply module 205, and an electrocardiogram module 206, etc.
[0163] It is understood that the structures illustrated in the embodiments of the present invention do not constitute a specific limitation on the electronic device. In other embodiments of this application, the electronic device may include more or fewer components than illustrated, or combine some components, or split some components, or have different component arrangements. The illustrated components may be implemented in hardware, software, or a combination of software and hardware.
[0164] Processor 201 may include one or more processing units, such as modem processors, digital signal processors, controllers, baseband processors, and / or neural network processors. These different processing units may be independent devices or integrated into one or more processors. Processor 201 may also be referred to as a microcontroller unit (MCU).
[0165] The controller can generate operation control signals based on the instruction opcode and timing signals to complete the control of instruction fetching and execution.
[0166] The processor 201 may also include a memory for storing instructions and data. In some embodiments, the memory in the processor 201 is a cache memory. This memory can store instructions or data that the processor 201 has just used or that are used repeatedly. If the processor 201 needs to use the instruction or data again, it can directly retrieve it from the memory. This avoids repeated accesses, reduces the waiting time of the processor 201, and thus improves the efficiency of the system.
[0167] The wireless communication module 204 can provide solutions for wireless communication applications in electronic devices, including wireless local area networks (WLANs) (such as wireless fidelity (Wi-Fi) networks), Bluetooth (BT), global navigation satellite system (GNSS), frequency modulation (FM), near field communication (NFC), infrared (IR), NearLink, and intrabody communication (IBC). For example, when two electronic devices communicate using an intrabody communication scheme, both devices have at least one electrode in contact with the skin. Through these skin-contact electrodes, the two electronic devices send and receive information via the human body. The wireless communication module 204 can be one or more devices integrating at least one communication processing module. The wireless communication module 204 receives electromagnetic waves via an antenna, performs frequency modulation and filtering of the electromagnetic wave signals, and sends the processed signal to the processor 201. The wireless communication module 204 can also receive the signal to be transmitted from the processor 201, frequency modulate it, amplify it, and convert it into electromagnetic waves for radiation via the antenna.
[0168] The memory 202 may include one or more random access memories and one or more non-volatile memories.
[0169] Non-volatile memory can include disk storage devices and flash memory.
[0170] The random access memory can be directly read and written by the processor 201. It can be used to store executable programs (such as machine instructions) of the operating system or other running programs, as well as user and application data.
[0171] Non-volatile memory can also store executable programs and user and application data, and can be pre-loaded into random access memory for direct reading and writing by the processor 201.
[0172] Sensor 203 may also include, but is not limited to, any one or more of the following: glucose detection sensor 2032, blood ketone detection sensor 2033, uric acid detection sensor 2034, lactic acid detection sensor 2035, etc. Optionally, sensor 203 may also include temperature sensor 2031.
[0173] Temperature sensor 2031 is used to detect temperature. In some embodiments, electronic device 100 uses the temperature detected by temperature sensor 2031 to determine the user's skin temperature and / or ambient temperature.
[0174] In some embodiments, the electronic device 200 can measure a user's blood glucose. Specifically, the electronic device 200 can measure the glucose concentration in tissue fluid (tissue fluid sugar) through the glucose detection sensor 2032 and then calculate the glucose concentration in plasma (blood) (blood glucose).
[0175] The glucose detection sensor 2032 is used to detect the concentration of glucose. In some embodiments, the glucose detection sensor 2032 can determine the glucose concentration by detecting the amount of oxygen consumed under the catalysis of glucose oxidase or the H2O2 generated by the oxidation of glucose in tissue fluid. In some embodiments, the glucose detection sensor 2032 uses an electronic medium, such as nanomaterials, osmium, ferrocene, benzoquinone, etc., to connect glucose oxidase to the electrode surface, and then achieves electron transfer through a series of redox reactions, thereby determining the glucose concentration.
[0176] During the process of a user measuring blood glucose using electronic device 200, the user can implant electronic device 200 into subcutaneous tissue. Electronic device 200 measures the glucose concentration in tissue fluid through the electrodes of glucose detection sensor 2032, thereby determining the user's blood glucose concentration.
[0177] In some embodiments, the electronic device 200 can measure the user's blood ketones. Specifically, the electronic device 200 can measure the concentration of ketone bodies in tissue fluid using a blood ketone detection sensor 2033, and then calculate the concentration of blood ketones in plasma (blood). Alternatively, the electronic device 200 can also measure the concentration of blood ketones in the blood.
[0178] The blood ketone detection sensor 2033 is used to detect the concentration of blood ketones. During the process of a user measuring blood ketones using the electronic device 200, the user can implant the electronic device 200 into subcutaneous tissue. The electronic device 200 measures the concentration of blood ketones in the tissue fluid through the electrodes of the blood ketone detection sensor 2033, thereby determining the user's blood ketone concentration. In other embodiments, the user can also drip sampled blood into the electronic device 200, and the electronic device 200 measures the concentration of blood ketones in the blood through the electrodes of the blood ketone detection sensor 2033.
[0179] In some embodiments, the electronic device 200 can measure uric acid in a user's body. Specifically, the electronic device 200 can measure the concentration of ketone bodies in tissue fluid using a uric acid detection sensor 2034, and then calculate the concentration of uric acid in plasma (blood). Alternatively, the electronic device 200 can also measure the concentration of uric acid in blood or the concentration of uric acid in a user's urine.
[0180] The uric acid detection sensor 2034 is used to detect the concentration of uric acid. During the process of a user measuring uric acid using the electronic device 200, the user can implant the electronic device 200 under the skin. The electronic device 200 measures the concentration of uric acid in the tissue fluid through the electrodes of the uric acid detection sensor 2034, thereby determining the user's uric acid concentration. In other embodiments, the user can also drip a sample of blood (or urine) into the electronic device 200, and the electronic device 200 measures the concentration of uric acid in the blood (or urine) through the electrodes of the uric acid detection sensor 2034.
[0181] The lactate detection sensor 2035 is used to detect blood lactate concentration. During the process of a user measuring blood lactate using the electronic device 200, the user can implant the electronic device 200 into subcutaneous tissue. The electronic device 200 measures the lactate concentration in the tissue fluid through the electrodes of the lactate detection sensor 2035, thereby determining the user's blood lactate concentration. In other embodiments, the user can also drip sampled blood (or tissue fluid) into the electronic device 200, and the electronic device 200 measures the lactate concentration in the blood (or tissue fluid) through the electrodes of the lactate detection sensor 2035.
[0182] In some embodiments, the electronic device 200 can transmit the collected physiological data to other devices, such as the electronic device 100, via the wireless communication module 204.
[0183] The memory 202 can be used to store physiological data collected by the electronic device 200, and optionally, it can also be used to store the user's body temperature.
[0184] The power module 205 may optionally include a battery 2051 and a power management module 2052, and may also include a charging management module 2053, etc.
[0185] The charging management module 2053 receives charging input from a charger. The charger can be a wireless charger or a wired charger. In some wired charging embodiments, the charging management module 2053 can receive charging input from a wired charger. In some wireless charging embodiments, the charging management module 2053 can receive wireless charging input through the wireless charging coil of the electronic device 100. While charging the battery 2051, the charging management module 2053 can also supply power to the electronic device through the power management module 2052.
[0186] The power management module 2052 connects the battery 2051, the charging management module 2053, and the processor 110. The power management module 2052 receives input from the battery 2051 and / or the charging management module 2053, supplying power to the processor 201, memory 202, wireless communication module 204, etc. The power management module 2052 can also monitor parameters such as battery capacity, battery cycle count, and battery health status (leakage current, impedance). In some other embodiments, the power management module 2052 may also be located within the processor 201. In other embodiments, the power management module 2052 and the charging management module 2053 may be housed in the same device.
[0187] The ECG module 206 can have ECG monitoring function to measure the user's ECG signal and obtain the user's ECG.
[0188] It should be understood that Figure 2B is only an exemplary illustration of the hardware structure of the electronic device 200. In other embodiments of this application, the electronic device 200 may contain more or fewer components, and this application embodiment does not limit this.
[0189] This application provides a measurement method applied to a first electronic device (also referred to as electronic device 200), the first electronic device including a first electrode group (also referred to as electrode group 1) and a second electrode group (also referred to as electrode group 2), the distance between the first electrode group and the second electrode group being greater than a first distance; when the first electrode group and the second electrode group are implanted in subcutaneous tissue, the method includes: determining a first physiological parameter through the first electrode group; and determining an electrocardiogram signal through the first electrode group and the second electrode group.
[0190] In this way, the user's electrocardiogram signal can be obtained anytime and anywhere through the electronic device 200. Moreover, it can also measure one or more other physiological parameters of the user at the same time (such as blood glucose, blood ketones, blood lactate, uric acid, etc.), thereby improving the efficiency of health monitoring.
[0191] The device form and internal structure of the electronic device 200 provided in the embodiments of this application are described below.
[0192] Figure 3A shows a schematic diagram of the device configuration of an electronic device 200 provided in an embodiment of this application.
[0193] As shown in Figure 3A, the electronic device 200 may include a base shell 301, multiple microneedle sensors, such as microneedle sensor 303 and microneedle sensor 304, and optionally, the electronic device 200 may also include a temperature-sensing heat-conducting column 302. Wherein:
[0194] In some embodiments, the bottom shell 301 can be connected to the temperature-sensing heat-conducting column 302, and the bottom shell 301 can also be connected to the plurality of microneedle sensors. In some embodiments, the temperature-sensing heat-conducting column 302 and the plurality of microneedle sensors can be embedded in the bottom shell 301 or welded to the bottom shell 301. This application does not limit the specific connection method.
[0195] The temperature-sensing heat-conducting column 302 can be used to measure a user's body temperature, such as measuring the user's skin temperature or the temperature of the user's subcutaneous tissue. In some embodiments, the temperature-sensing heat-conducting column 302 can be in contact with the user's skin to measure the user's skin temperature. In some embodiments, the temperature-sensing heat-conducting column 302 can also be implanted into the subcutaneous tissue. In other embodiments, the temperature-sensing heat-conducting column 302 can also be replaced by one or more temperature electrodes, which can also be disposed in the plurality of microneedle sensors and implanted into the subcutaneous tissue.
[0196] Microneedle sensors can be implanted in a user's subcutaneous tissue. Each microneedle sensor may include an electrode assembly, which can be used to measure one or more physiological parameters. Each electrode assembly may include two or more electrochemical electrodes. In some embodiments, the electrode assembly may include one or more working electrodes and one or more counter electrodes (or reference electrodes), which can constitute one or more dual-electrode systems through which one or more physiological parameters can be measured. In other embodiments, the electrode assembly may include one or more working electrodes, one or more counter electrodes, and one or more reference electrodes, which can constitute one or more tri-electrode systems through which one or more physiological parameters can be measured. In other embodiments, optionally, the electrode assembly may also include one or more electrocardiogram (ECG) electrodes, such as one or more of the following: LA electrode, RA electrode, and RLD electrode.
[0197] For example, the plurality of microneedle sensors may include microneedle sensor 303 and microneedle sensor 304. Microneedle sensor 303 may include electrode group 1, and microneedle sensor 304 may include electrode group 2. Electrode group 1 may include at least one working electrode and at least one counter electrode. Optionally, electrode group 1 may also include one or more reference electrodes. Further optionally, electrode group 1 may also include one or more electrocardiogram (ECG) electrodes. Similarly, electrode group 2 may include at least one working electrode and at least one counter electrode. Optionally, electrode group 2 may also include one or more reference electrodes. Further optionally, electrode group 2 may also include one or more ECG electrodes. Electrode group 1 can be used to measure the user's physiological parameters, and electrode group 2 can also be used to measure the user's physiological parameters, which may include, but are not limited to, any one or more of the following: blood glucose, blood ketones, uric acid, blood lactate, etc. The physiological parameters measured by electrode group 1 and electrode group 2 may be the same or different.
[0198] For example, electrode group 1 in microneedle sensor 303 can be used to measure a user's blood glucose, and electrode group 2 in microneedle sensor 304 can be used to measure a user's blood ketones. It is understood that the embodiments described here are merely illustrative of how each microneedle sensor can be used to measure one or more physiological parameters. In the embodiments of this application, microneedle sensors 303 and 304 can also be used to measure physiological parameters different from those described in the above embodiments, and this application does not limit the scope of the application.
[0199] It should be noted that the distance between the microneedle sensor 303 and the microneedle sensor 304 is greater than or equal to a preset distance (e.g., 3 cm). This ensures that the user's electrocardiogram signal can be obtained through these two microneedle sensors.
[0200] It is understood that the embodiment shown in FIG3A is only an example. In the embodiments of this application, the electronic device 200 may also adopt a different device form than the above embodiment, such as including more microneedle sensors than the above embodiment, or including more, fewer or different elements than the above embodiment. This application does not limit it here.
[0201] Figure 3B shows a schematic diagram of the internal structure of an electronic device 200 provided in an embodiment of this application.
[0202] As shown in Figure 3B, the electronic device 200 may include a microneedle sensor 303, a microneedle sensor 304, a printed circuit board (PCB) 305, and a battery 306. Optionally, the electronic device 200 may also include a temperature-sensing heat-conducting pillar 302. Wherein:
[0203] The temperature-sensing heat-conducting column 302 can be connected to the PCB 305 to transmit the measured temperature to the PCB 305. Other specific details of the temperature-sensing heat-conducting column 302 can be found in the relevant description in the embodiment shown in Figure 3A above, and will not be repeated here.
[0204] The microneedle sensor 303 can be equipped with an electrode assembly 1, which may include multiple electrochemical electrodes, such as a working electrode (WE) 3031 and a counter electrode (CE) 3033. Optionally, the electrode assembly 1 may also include a reference electrode (RE) 3032. The electrode assembly 1 is used to measure physiological parameter 1 (e.g., blood glucose, blood ketones, uric acid, blood lactate, etc.). In the electrode assembly 1, the working electrode 3031 can react with the target substance 1 corresponding to the physiological parameter 1 to generate a reaction current. For example, if the physiological parameter 1 is blood glucose, the target substance 1 can be glucose; or, for example, if the physiological parameter 1 is blood ketones, the target substance can be ketone bodies, etc. The reference electrode 3032 can be used to control the voltage of the working electrode 3031. The counter electrode 3033 can be used to form a circuit with the working electrode 3031 to ensure the generation and conduction of the reaction current. In some embodiments, the electrode assembly 1 can form a dual-electrode system through the working electrode 3031 and the counter electrode 3033, and form a circuit through this dual-electrode system to ensure the generation and conduction of the reaction current. In other embodiments, electrode assembly 1 can be configured as a three-electrode system consisting of a working electrode 3031, a counter electrode 3033, and a reference electrode 3032, forming a circuit to ensure the generation and conduction of the reaction current. This two-electrode system and the three-electrode system can be used to measure physiological parameter 1.
[0205] The microneedle sensor 304 can be equipped with an electrode group 2, which may include multiple electrochemical electrodes, such as a working electrode (WE) 3041 and a counter electrode (CE) 3043. Optionally, the electrode group 2 may also include a reference electrode (RE) 3042. The electrode group 2 is used to measure physiological parameter 2 (e.g., blood glucose, blood ketones, uric acid, blood lactate, etc.). It should be noted that physiological parameter 1 may be different from physiological parameter 2; in some embodiments, physiological parameter 1 may also be the same as physiological parameter 2. The function of each electrode in the electrode group 2 can be compared with the function of each electrode in the electrode group 1 described above. The electrode group 2 may also be configured as a two-electrode system or a three-electrode system based on the type and number of electrochemical electrodes, and physiological parameter 2 can be measured through the two-electrode system or the three-electrode system.
[0206] Electrode sets 1 and 2 can also be used to measure the user's electrocardiogram (ECG) signals.
[0207] In some embodiments, the electrochemical electrodes in electrode group 1 and electrode group 2 can be used as electrocardiogram (ECG) electrodes to measure ECG signals. Any electrode in electrode group 1 and any electrode in electrode group 2 can be used as an LA electrode and RA electrode, respectively. The RLD electrode can be an electrode in electrode group 1 or an electrode in electrode group 2, and the RLD electrode is connected to a right leg drive circuit, which is used to cancel common-mode signals. For example, RE3032 in microneedle sensor 303 can be used as an LA electrode, WE3041 in microneedle sensor 304 can be used as an RA electrode, and CE3043 can be used as an RLD electrode. It is understood that the embodiments described here are merely examples. In the embodiments of this application, other electrodes in electrode group 1 and electrode group 2 can also be selected as ECG electrodes to measure ECG signals; this application does not limit this. In the above cases, some electrochemical electrodes in electrode group 1 and electrode group 2 can measure both the user's physiological parameters and the user's ECG signals.
[0208] In other embodiments, separate ECG electrodes can be provided in electrode groups 1 and 2 for measuring ECG signals. Specifically, the LA and RA electrodes are located in different electrode groups, while the RLD electrode can be located in either electrode group. In this case, ECG signals can be measured using these electrodes, and these electrodes are used solely for measuring ECG signals.
[0209] In other embodiments, electrode groups 1 and 2 may each contain individual electrocardiogram (ECG) electrodes. Furthermore, some of the electrochemical electrodes in electrode groups 1 and 2 may also be used as ECG electrodes. For example, electrode group 1 may contain an RLD electrode, and one of the electrochemical electrodes in electrode group 1 and electrode group 2 may be selected as the LA electrode and RA electrode, respectively. Thus, ECG signals can be measured using the RLD electrode and multiple electrochemical electrodes. It is understood that this is merely illustrative, and some electrodes in the ECG array may use the electrochemical electrodes in electrode groups 1 and 2. In the embodiments of this application, more, fewer, or different ECG electrodes than those described in the above embodiments may be provided, or other electrochemical electrodes may be used as ECG electrodes to measure ECG signals. This application does not impose any limitations on this.
[0210] PCB 305 can acquire the user's electrocardiogram (ECG) signal through microneedle sensors 303 and 304. It can also acquire the user's physiological data 1 through microneedle sensor 303, which is used to determine physiological parameter 1. PCB 305 can also acquire the user's physiological data 2 through microneedle sensor 304, which can be used to determine physiological parameter 2. PCB 305 may include multiple circuit modules. The internal circuit structure of these modules and the connection relationships between them can be referred to the relevant content in the embodiments shown in Figures 4A-4J below, and will not be detailed here.
[0211] Battery 306 can be used to power multiple modules in electronic device 200, such as powering PCB 305. In some embodiments, battery 306 can be a lithium battery, and in other embodiments, battery 306 can also be a battery made of other materials, which is not limited herein.
[0212] It is understood that the embodiment shown in Figure 3B above is only an example. In some embodiments, the electronic device 200 may also include more microneedle sensors than in the above embodiment, and the microneedle sensors may also include more or fewer electrochemical electrodes than in the above embodiment. This application does not limit the scope of the invention.
[0213] Figure 3C shows a schematic diagram of the electrode distribution on a microneedle sensor 303 provided in an embodiment of this application.
[0214] As shown in Figure 3C, the microneedle sensor 303 may include a supradermal portion and a subcutaneous portion. The subcutaneous portion is for implantation into the user's subcutaneous tissue, and the supradermal portion is for connection to the PCB 305. For example, the microneedle sensor 303 may be an irregularly shaped sheet that may include two opposing surfaces, namely surface A and surface B.
[0215] An electrode assembly 1 may be disposed on the microneedle sensor 303. A detailed description of the electrode assembly 1 can be found in the embodiments shown in Figures 3A and 3B. Exemplarily, the electrode assembly 1 may include a working electrode 3031, a reference electrode 3032, and a counter electrode 3033. In some embodiments, all electrochemical electrodes in the electrode assembly 1 may be disposed on surface A of the microneedle sensor 303. Each electrochemical electrode may include a measuring end, a conducting end, and a wire for connecting the measuring end and the conducting end. The measuring ends of the one or more electrochemical electrodes are disposed on surface A of the subcutaneous portion, and the conducting ends of the one or more electrochemical electrodes are disposed on surface A of the supracutaneous portion.
[0216] It is understood that the embodiment shown in Figure 3A is merely an illustrative example illustrating that all electrodes on the microneedle sensor 303 can be disposed on the same surface of the microneedle sensor 303. In other embodiments, the electrodes on the microneedle sensor 303 can also be disposed on different surfaces of the microneedle sensor 303, for example, the working electrode 3031 can be disposed on surface A, and the reference electrode 3032 and the counter electrode 3033 can be disposed on surface B. This application does not limit this. Furthermore, in other embodiments, the microneedle sensor 303 can also adopt a different shape than that shown in Figure 3C, such as needle-shaped, cylindrical, triangular prism, polyhedral, etc. This application does not limit the specific shape of the microneedle sensor 303.
[0217] Thus, when the microneedle sensor 303 is implanted in the subcutaneous tissue of the user, the microneedle sensor 303 can acquire the user's physiological data 1 through one or more electrochemical electrodes.
[0218] In other embodiments, the microneedle sensor 303 may also include multiple working electrodes. In one possible implementation, two or more working electrodes may share the same reference electrode and / or counter electrode, forming different three-electrode systems (or two-electrode systems) to measure the same or different physiological parameters, such as blood glucose and blood ketones. In another possible implementation, the microneedle sensor 303 may also include multiple reference electrodes and / or counter electrodes. These multiple working electrodes may form different three-electrode systems (or two-electrode systems) with different reference electrodes and / or counter electrodes to measure the same or different physiological parameters.
[0219] It should be noted that the electrode distribution on the microneedle sensor 304 can also refer to the electrode distribution of the microneedle sensor 303 shown in Figure 3C above. In addition, if the electronic device 200 also includes other microneedle sensors, the electrode distribution on the microneedle sensor can also refer to the relevant description in the embodiment shown in Figure 3C above. This application will not repeat it here.
[0220] Figure 3D shows a schematic diagram of the device configuration of another electronic device 200 provided in an embodiment of this application.
[0221] As shown in Figure 3D, the electronic device 200 may include a base shell 301 and multiple array sensors. Each array sensor may include an electrode group. The specific details of the electrode group can be found in the relevant description in the embodiment shown in Figure 3A above, and will not be repeated here. Optionally, the electronic device 200 may also include a temperature-sensing heat-conducting column 302. The specific details of the temperature-sensing heat-conducting column 302 can be found in the relevant description in the embodiments shown in Figures 3A-3B above, and will not be repeated here. In some embodiments, the multiple array sensors may be disposed on the base shell 301, and optionally, a temperature-sensing heat-conducting column 302 may also be disposed thereon. In the embodiments of this application, a sensor may refer to a component used to acquire a specific signal (e.g., current signal, voltage signal, light signal, etc.). In some embodiments, an array sensor may also refer to multiple electrodes arranged in an array.
[0222] For example, the plurality of array sensors may include array sensor 307 and array sensor 308. Array sensor 307 may include electrode group 1, and array sensor 308 may include electrode group 2.
[0223] Electrode group 1 may include multiple electrochemical electrodes, such as a working electrode group 3073 and a counter electrode group 3075, and optionally, a reference electrode group 3074. Further optionally, it may include one or more electrocardiogram electrodes, such as a right leg drive (RLD) electrode 3072 and a right arm (RA) electrode 3071. Each electrode group may include one or more electrochemical electrodes of the same type. In some embodiments, the working electrode group 3073 and the counter electrode group 3075 in electrode group 1 may constitute one or more dual-electrode systems, each dual-electrode system forming a circuit to ensure the generation and conduction of reaction current. Through this dual-electrode system, electrode group 1 can measure one or more physiological parameters. In other embodiments, the working electrode group 3073, the reference electrode group 3074, and the counter electrode group 3075 in electrode group 1 may constitute one or more three-electrode systems, each three-electrode system forming a circuit to ensure the generation and conduction of reaction current. It should be noted that in some embodiments, multiple dual-electrode systems (or three-electrode systems) may share a counter electrode and / or a reference electrode. Using a two-electrode system and / or a three-electrode system, electrode group 1 can measure physiological parameters 1.
[0224] Electrode group 2 may include multiple electrochemical electrodes, such as a working electrode group 3082 and a counter electrode group 3084, and optionally, a reference electrode group 3083. Further optionally, it may include one or more electrocardiogram electrodes, such as a left arm (LA) electrode 3081. Each electrode group may include one or more electrochemical electrodes of the same type. In some embodiments, the working electrode group 3082 and the counter electrode group 3084 in electrode group 2 may constitute one or more dual-electrode systems, each dual-electrode system forming a circuit to ensure the generation and conduction of reaction current. Through this dual-electrode system, electrode group 2 can measure one or more physiological parameters. In other embodiments, the working electrode group 3082, the reference electrode group 3083, and the counter electrode group 3084 in electrode group 2 may constitute one or more tri-electrode systems, each tri-electrode system forming a circuit to ensure the generation and conduction of reaction current. It should be noted that in some embodiments, multiple dual-electrode systems (or tri-electrode systems) may share a counter electrode and / or a reference electrode. Through the dual-electrode system and / or the tri-electrode system, electrode group 2 can measure physiological parameter 2.
[0225] It is understood that the above embodiments are merely illustrative of the fact that electrode group 1 and electrode group 2 may include one or more ECG electrodes. In the embodiments of this application, it is only necessary to ensure that the LA electrode and RA electrode are located in different electrode groups, and the RLD electrode can be located in any electrode group. This application does not limit the specific correspondence between ECG electrodes and electrode groups.
[0226] In other embodiments, separate ECG electrodes may be provided in electrode groups 1 and 2, such as a left arm (LA) electrode 3081, a right leg drive (RLD) electrode 3072, and a right arm (RA) electrode 3071. In this case, ECG signals can be measured using the ECG electrodes, and the aforementioned ECG electrodes are used solely for measuring ECG signals.
[0227] In some embodiments, the electrochemical electrodes in electrode group 1 and electrode group 2 can be used as ECG electrodes to measure ECG signals. Any electrode in electrode group 1 and any electrode in electrode group 2 can serve as an LA electrode and RA electrode, respectively. The RLD electrode can be an electrode in electrode group 1 or an electrode in electrode group 2, and the RLD electrode is connected to a right leg drive circuit, which is used to cancel common-mode signals. For example, one or more reference electrodes in the reference electrode group 3074 in electrode group 1 can serve as LA electrodes, one or more working electrodes in the working electrode group 3082 in electrode group 2 can serve as RA electrodes, and one or more counter electrodes in the counter electrode group 3084 can serve as RLD electrodes. It is understood that the embodiments described here are merely examples. In the embodiments of this application, other electrodes in electrode group 1 and electrode group 2 can also be selected as ECG electrodes to measure ECG signals; this application does not limit this. In the above cases, some electrochemical electrodes in electrode group 1 and electrode group 2 can measure both the user's physiological parameters and the user's ECG signals.
[0228] In other embodiments, electrode groups 1 and 2 may each contain a separate electrocardiogram (ECG) electrode. Furthermore, some of the electrochemical electrodes in electrode groups 1 and 2 can also be used as ECG electrodes. For example, electrode group 1 may contain an RLD electrode, and one of the electrochemical electrodes in electrode groups 1 and 2 may be selected as the LA electrode and RA electrode, respectively. Thus, ECG signals can be measured using the RLD electrode and multiple electrochemical electrodes. It is understood that this is merely illustrative; some electrodes in the ECG electrode set may use the electrochemical electrodes in electrode groups 1 and 2. In the embodiments of this application, other electrochemical electrodes may also be used as ECG electrodes to measure ECG signals, and this application does not impose limitations.
[0229] In the array sensors 307 and 308 described above, the specific functions of the working electrode, reference electrode, and counter electrode can be compared with the functional descriptions of each electrode in the embodiment shown in Figure 3B above, and will not be repeated here.
[0230] It should be noted that the distance between array sensor 307 and array sensor 308 is greater than or equal to a preset distance (e.g., 3 cm), which ensures that the user's electrocardiogram signal can be obtained through these two array sensors.
[0231] It is understood that the embodiment shown in Figure 3D is only an example. In the embodiments of this application, the electronic device 200 may also adopt a device form different from the above embodiments. For example, it may include more array sensors than the above embodiments, or include more, fewer or different electrodes (including electrocardiogram electrodes and electrochemical electrodes) than the above embodiments, or include more, fewer or different elements than the above embodiments. This application does not limit it.
[0232] It should be noted that the embodiments shown in Figures 3A and 3D above are only two examples. In the embodiments of this application, the electronic device 200 may also include one or more array sensors and one or more microneedle sensors. The microneedle sensor may include multiple electrodes, and the array sensor may also include multiple electrodes. The electronic device 200 may also determine one physiological parameter through an array sensor and another physiological parameter through a microneedle sensor. It may also acquire electrocardiogram signals through the microneedle sensor and the array sensor. This application does not limit this.
[0233] Figure 3E shows a schematic diagram of the internal structure of an electronic device 200 provided in an embodiment of this application.
[0234] As shown in Figure 3E, the electronic device 200 may include an array sensor 307, an array sensor 308, a printed circuit board (PCB) 305, and a battery 306. Optionally, the electronic device 200 may also include a temperature-sensing heat-conducting column 302. Wherein:
[0235] The temperature-sensing heat-conducting column 302 can be connected to the PCB 305 to transmit the measured temperature to the PCB 305. Other specific details of the temperature-sensing heat-conducting column 302 can be found in the relevant description in the embodiment shown in Figure 3D above, and will not be repeated here.
[0236] The electrode configuration in array sensor 307 (i.e., the electrode configuration in electrode group 1) and the electrode configuration in array sensor 308 (i.e., the electrode configuration in electrode group 2) can be referred to the relevant description in the embodiment shown in Figure 3D above, and will not be repeated here. It should be noted that array sensor 307 and array sensor 308 can be mounted on PCB 305 or connected to PCB.
[0237] In some embodiments, PCB 305 can acquire the user's electrocardiogram (ECG) signal through array sensors 307 and 308, and can also acquire the user's physiological data 1 through array sensor 307. Physiological data 1 is used to determine physiological parameter 1. PCB 305 can also acquire the user's physiological data 2 through array sensor 308. Physiological data 2 can be used to determine physiological parameter 2. PCB 305 may include multiple circuit modules. The internal circuit configuration of these multiple circuit modules and the connection relationship between the circuit modules can be referred to the relevant content in the embodiments shown in Figures 4A-4J below, which will not be detailed here. It should be noted that physiological parameter 1 may include one or more physiological parameters. In some embodiments, multiple working electrodes in array sensor 307 can be used to acquire physiological data of different physiological parameters. In this case, multiple different physiological parameters, such as blood glucose and blood ketones, can be determined based on physiological data 1. This application does not limit this. It is understood that physiological parameter 2 may also include one or more physiological parameters.
[0238] Battery 306 can be used to power multiple modules in electronic device 200, such as powering PCB 305. In some embodiments, battery 306 can be a lithium battery, and in other embodiments, battery 306 can also be a battery made of other materials, which is not limited herein.
[0239] It is understood that the embodiment shown in Figure 3E above is only an example. In some embodiments, the electronic device 200 may also include more array sensors than in the above embodiment, and the array sensor 307 and / or array sensor 308 may also include more or fewer electrodes (including ECG electrodes and electrochemical electrodes) than in the above embodiment. This application does not limit the scope of the invention.
[0240] The connection relationships between the various circuit modules in the PCB305 provided in the embodiments of this application are described below.
[0241] Figure 4A shows a schematic diagram of the connection relationship between various circuit modules in a PCB 305 provided in an embodiment of this application.
[0242] As shown in Figure 4A, PCB 305 may include a microcontroller unit (MCU) 401, an analog-to-digital converter (ADC) 402, an electrocardiogram (ECG) circuit module 403, one or more electrochemical circuit modules (e.g., electrochemical circuit modules 404 and 405), one or more electrode interfaces (e.g., electrode interface 406 and electrode interface 407), etc. Optionally, PCB 305 may also include a temperature module 408, etc. In some embodiments, ADC 402 may also be integrated into MCU 401. Wherein:
[0243] The ECG circuit module 403 can be connected to ECG electrodes. When using a bipolar lead system to measure ECG, the ECG electrodes may include an LA electrode, a RA electrode, and a RLD electrode. The LA and RA electrodes can measure ECG signal 1 and transmit it to the ECG circuit module 403. The ECG circuit module 403 can amplify and filter ECG signal 1 to obtain ECG signal 2, and send ECG signal 2 to the ADC 402. In some embodiments, the ECG circuit module 403 may include an amplification circuit 4031, a filtering circuit 4032, and a right leg drive (RLD) circuit 4033. The amplification circuit 4031 can be connected to the LA and RA electrodes, and the RLD circuit 4033 can be connected to the RLD electrode. The amplification circuit 4031 receives ECG signal 1 and amplifies it. The RLD circuit 4033 cancels common-mode signals, and the filtering circuit 4032 filters the amplified ECG signal 1 to obtain ECG signal 2.
[0244] The one or more electrochemical circuit modules may include electrochemical circuit module 404 and electrochemical circuit module 405. Each electrochemical circuit can measure a physiological parameter, such as blood glucose, blood ketones, uric acid, blood lactate, etc. The physiological parameters measured by electrochemical circuit module 404 and electrochemical circuit module 405 may be the same or different.
[0245] Electrochemical circuit module 404 can be connected to one or more electrochemical electrodes. In the case of measuring physiological parameters using a three-electrode system, electrochemical circuit module 404 can be connected to one or more working electrodes, one or more reference electrodes, and one or more counter electrodes. These one or more electrochemical electrodes can react with the target substance 1 to generate a current signal 1, which is then transmitted to electrochemical circuit module 404. Electrochemical circuit module 404 can amplify and process the current signal 1 to obtain a current signal 2, and send the current signal 2 to ADC 402. In some embodiments, electrochemical circuit module 404 may include a potentiostat circuit 4041 and a transimpedance circuit 4042. The potentiostat circuit 4041 can control the voltage difference between the reference electrode and the working electrode. The transimpedance circuit 4042 can amplify the current signal 1 to obtain the current signal 2. In some embodiments, the potentiostat circuit 4041 and the transimpedance circuit 4042 may have overlapping portions. For example, there may be one or more components shared by the potentiostat circuit 4041 and the transimpedance circuit 4042. Specific examples can be found in the embodiments shown in Figures 4C-4D and 4F-4J below, which will not be detailed here.
[0246] The electrochemical circuit module 405 can be connected to one or more electrochemical electrodes. In the case of measuring physiological parameters using a three-electrode system, the electrochemical circuit module 405 can be connected to one or more working electrodes, one or more reference electrodes, and one or more counter electrodes. These one or more electrochemical electrodes can react with the target substance 2 to generate a current signal 3, which is then transmitted to the electrochemical circuit module 405. The electrochemical circuit module 405 can amplify and process the current signal 3 to obtain a current signal 4, and then send the current signal 4 to the ADC 402. In some embodiments, the electrochemical circuit module 405 may include a potentiostat circuit 4051 and a transimpedance circuit 4052. The potentiostat circuit 4051 can control the voltage difference between the reference electrode and the working electrode. The transimpedance circuit 4052 can amplify the current signal 3 to obtain the current signal 4. In some embodiments, the potentiostat circuit 4051 and the transresistance circuit 4052 may have overlapping portions. For example, there may be one or more components shared by the potentiostat circuit 4051 and the transresistance circuit 4052. Specific examples can be found in the embodiments shown in Figures 4C-4D and 4F-4J below, which will not be detailed here.
[0247] The one or more electrode interfaces may include electrode interface 406 and electrode interface 407. The electrode interfaces can connect the electrochemical circuit module to one or more electrochemical electrodes, and can also connect the electrocardiogram circuit module 403 and electrocardiogram electrodes.
[0248] In some embodiments, electrode interface 406 can connect electrochemical circuit module 404 to one or more electrochemical electrodes. Electrode interface 406 can also connect ECG circuit module 403 and LA electrode. Electrode interface 407 can connect electrochemical circuit module 405 to one or more electrochemical electrodes, and electrode interface 407 can also connect ECG circuit module 403 to RA electrode and RLD electrode.
[0249] For example, if the electronic device 200 is the electronic device 200 shown in Figures 3A-3B above, the electrochemical electrode connected to the electrode interface 406 may include the working electrode 3031, the reference electrode 3032, and the counter electrode 3033 in the embodiment shown in Figure 3B above, and the LA electrode connected to the electrode interface 406 may be the reference electrode 3032; the electrochemical electrode connected to the electrode interface 407 may include the working electrode 3041, the reference electrode 3042, and the counter electrode 3043 in the embodiment shown in Figure 3B above, and the RA electrode connected to the electrode interface 407 may be the working electrode 3041, and the RLD electrode may be the counter electrode 3043.
[0250] For example, if the electronic device 200 is the electronic device 200 shown in Figures 3D-3E above, then the electrochemical electrode connected to the electrode interface 406 may include the working electrode group 3082, the reference electrode group 3083, and the counter electrode group 3084 in the embodiment shown in Figure 3D above, and the LA electrode connected to the electrode interface 406 may be the LA electrode 3081; the electrochemical electrode connected to the electrode interface 407 may include the working electrode group 3073, the reference electrode group 3074, and the counter electrode group 3075 in the embodiment shown in Figure 3D above, and the RA electrode connected to the electrode interface 407 may be the RA electrode 3071, and the RLD electrode may be the RLD electrode 3072. It is understood that the above two embodiments are only examples. In the embodiments of this application, the connection relationship between the electrode interface and the electrode (including the electrochemical electrode and the ECG electrode) may also be a different connection relationship than the above embodiments, and this application does not limit it here.
[0251] ADC402 can receive current signals (e.g., current signal 2, current signal 4, etc.) sent by one or more electrochemical circuit modules. ADC402 can also receive analog ECG signal 2 sent by ECG circuit module 403. ADC402 can perform analog-to-digital conversion on the received analog signals (e.g., current signal 2, current signal 4, ECG signal 2, etc.) to obtain the corresponding digital signals. For example, ADC402 can perform analog-to-digital conversion on current signal 2 to obtain current signal 5. ADC402 can perform analog-to-digital conversion on current signal 4 to obtain current signal 6. ADC402 can also perform analog-to-digital conversion on ECG signal 2 to obtain ECG signal 3. The aforementioned current signals 5, 6, and ECG signal 3 are all digital signals.
[0252] MCU401 can receive digital signals (e.g., current signal 5, current signal 6, and ECG signal 3) sent by ADC402, and can also receive temperature signals sent by temperature module 408. MCU401 can determine the user's electrocardiogram (ECG) based on ECG signal 3 sent by ADC402. MCU401 can determine the user's physiological parameter 1 based on current signal 5 sent by ADC402, and MCU401 can also determine the user's physiological parameter 2 based on current signal 6. Optionally, MCU401 can also determine the user's body temperature based on the temperature signals.
[0253] Temperature module 408 can detect temperature signals and send them to MCU 401.
[0254] In some embodiments, PCB305 may further include a charging circuit module 409, which can supply power to other modules in PCB305.
[0255] The charging circuit module 409 may include a charging management chip 4092 and a voltage regulator circuit 4094. Optionally, the charging circuit module 409 may also include a battery 4093 and a charging interface 4091. In some embodiments, the battery 4093 may not be disposed in the PCB 305, but may be connected to the charging circuit module 409 in the PCB 305.
[0256] The charging interface 4091 can receive charging input (such as wired charger input, wireless charging input, etc.). The charging interface 4091 can charge the battery 4093 through the charging management chip 4092, and can also transfer electrical energy to the voltage regulator circuit 4094 through the charging management chip 4092.
[0257] The voltage regulator circuit 4094 can provide stable power to other circuit modules in PCB 305. The voltage regulator circuit 4094 can receive power from the charging management chip 4092 and also from the battery 4093.
[0258] It is understood that the embodiment shown in Figure 4A is only an example. In the embodiments of this application, PCB305 may also include more, fewer or different circuit modules (e.g., electrochemical circuit modules, electrode interfaces, etc.) than the above embodiments. Moreover, the connection relationship between the circuit modules in PCB305 may also be a different connection relationship than the above embodiments. This application does not limit this.
[0259] In some embodiments, the same electrochemical circuit module in PCB305 can be used to measure multiple physiological parameters, and PCB305 can control the physiological parameters measured by the electrochemical circuit module through one or more switching switches.
[0260] For example, Figure 4B shows a schematic diagram of the connection relationship of various circuit modules in another PCB305 provided in an embodiment of this application.
[0261] As shown in Figure 4B, PCB 305 may include a microcontroller unit (MCU), an analog-to-digital converter (ADC) 402, an electrocardiogram (ECG) circuit module 403, a switching switch MUX0, one or more electrochemical circuit modules (e.g., electrochemical circuit module 404), one or more electrode interfaces (e.g., electrode interface 406, electrode interface 407), etc. Optionally, PCB 305 may also include, but is not limited to, any one or more of the following: a temperature module 408, a charging circuit module 409, etc. Wherein:
[0262] The input terminal of the switch MUX0 can be connected to electrode interface 406 and electrode interface 407. The output terminal of the switch MUX0 can be connected to electrochemical circuit module 404. The switch MUX0 can activate either electrode interface 406 or electrode interface 407.
[0263] The electrochemical circuit module 404 can be connected to multiple electrochemical electrodes via the switching switch MUX0.
[0264] When MUX0 is connected to electrode interface 406, electrochemical circuit module 404 can connect one or more electrochemical electrodes through MUX0 and electrode interface 406. In the case of measuring physiological parameters using a three-electrode system, these one or more electrochemical electrodes may include one or more working electrodes, one or more reference electrodes, and one or more counter electrodes. These one or more electrochemical electrodes can react with target substance 1 to generate current signal 1, and transmit this current signal 1 to electrochemical circuit module 404. Electrochemical circuit module 404 can amplify and process this current signal 1 to obtain current signal 2, and send current signal 2 to ADC 402.
[0265] When the MUX0 is connected to the electrode interface 407, the electrochemical circuit module 404 can connect one or more electrochemical electrodes through the MUX0 and the electrode interface 407. In the case of measuring physiological parameters using a three-electrode system, these one or more electrochemical electrodes may include one or more working electrodes, one or more reference electrodes, and one or more counter electrodes. These one or more electrochemical electrodes can react with the target substance 2 to generate a current signal 3, which is then transmitted to the electrochemical circuit module 404. The electrochemical circuit module 404 can amplify and process the current signal 3 to obtain a current signal 4, which is then sent to the ADC 402.
[0266] In some embodiments, the electrochemical circuit module 404 may include a potentiostat circuit 4041 and a transresistance circuit 4042. The potentiostat circuit 4041 can control the voltage difference between the reference electrode and the working electrode. The transresistance circuit 4042 can amplify the current signal, for example, amplifying current signal 1 to obtain current signal 2, or amplifying current signal 3 to obtain current signal 4. In some embodiments, there may be overlap between the potentiostat circuit 4041 and the transresistance circuit 4042, for example, there may be one or more components shared by the potentiostat circuit 4041 and the transresistance circuit 4042. Specific examples can be found in the embodiments shown in Figures 4C-4D and 4F-4J below, which will not be detailed here.
[0267] The one or more electrode interfaces may include electrode interface 406 and electrode interface 407. The electrode interfaces can connect the electrochemical circuit module to one or more electrochemical electrodes, and can also connect the ECG circuit module 403 to the ECG electrodes. In some embodiments, electrode interface 406 can connect the switching switch MUX0 to one or more electrochemical electrodes. Electrode interface 406 can also connect the ECG circuit module 403 to the LA electrode. Electrode interface 407 can connect the switching switch MUX0 to one or more electrochemical electrodes, and electrode interface 407 can also connect the ECG circuit module 403 to the RA electrode and the RLD electrode. The connection relationships between electrode interfaces 406 and 407 and the various electrodes can be referred to the relevant descriptions in the embodiments shown in Figure 4A above, and will not be repeated here.
[0268] Furthermore, the specific details of MCU401, ADC402, ECG circuit module 403, temperature module 408, and charging circuit module 409 can be found in the relevant descriptions in the embodiment shown in Figure 4A above, and will not be repeated here.
[0269] It is understood that the embodiment shown in Figure 4B is merely an example. In the embodiments of this application, PCB305 may also include more, fewer, or different circuit modules (e.g., electrochemical circuit modules, electrode interfaces, etc.) than the above embodiments. Moreover, the connection relationships between the circuit modules in PCB305 may also be different from those in the above embodiments, and this application does not impose any limitations on them. Furthermore, in some embodiments, a single electrochemical module may be used to measure two or more physiological parameters, and this application does not impose any limitations on it either.
[0270] In other embodiments, the PCB305 may have more or fewer switching switches, or the switching switches may be set at different locations than those in the embodiment shown in FIG4B above. These switching switches can be used to control the PCB305 to measure current signals / ECG signals of specified physiological parameters at the same time, or to measure ECG signals and current signals of one or more physiological parameters at the same time.
[0271] The following section uses the example of electrode group 1 and electrode group 2 both constituting a three-electrode system to introduce various measurement circuits provided in the embodiments of this application.
[0272] Figure 4C shows a circuit diagram of a measurement circuit provided in an embodiment of this application.
[0273] As shown in Figure 4C, the measurement circuit may include a potentiostat circuit 1, a transimpedance circuit 1, a potentiostat circuit 2, a transimpedance circuit 2, a right leg drive circuit, an amplifier circuit, a filter circuit, an analog-to-digital converter (ADC) module, and an MCU, etc. Optionally, the measurement circuit may also include any one or more of the following: a Discrete Fourier Transform (DFT) module and a temperature module (temp), etc. Furthermore, the measurement circuit may include multiple electrode groups, such as electrode group 1 and electrode group 2. For example, electrode group 1 may include a working electrode W1, a reference electrode R1, and a counter electrode C1; electrode group 2 may include a working electrode W2, a reference electrode R2, and a counter electrode C2.
[0274] The components in each circuit module and their connection methods are described below.
[0275] The potentiostat circuit 1 may include a digital-to-analog converter module DAC1, operational amplifier AMP_1, and operational amplifier AMP_2. Each operational amplifier may include a non-inverting input, an inverting input, and an output. DAC1 generates a stable voltage signal. DAC1 can be connected to the non-inverting input of operational amplifier AMP_1 and also to the non-inverting input of operational amplifier AMP_2, providing the same voltage input to both operational amplifiers AMP_1 and AMP_2. The output of operational amplifier AMP_1 can be connected to the counter electrode C1 in electrode group 1, and the inverting input of operational amplifier AMP_1 can be connected to the reference electrode R1 in electrode group 1. The inverting input of operational amplifier AMP_2 can be connected to the working electrode W1 in electrode group 1, and the output of operational amplifier AMP_2 can be connected to the ADC. Thus, by applying the same voltage to the non-inverting inputs of operational amplifiers AMP_1 and AMP_2, the voltage difference between the reference electrode R1 and the working electrode W1 can be controlled, making the voltage on the working electrode W1 approximately equal to the voltage on the reference electrode R1.
[0276] The transimpedance circuit 1 may include an operational amplifier AMP_2 and a resistor RTIA_1. The two ends of the resistor RTIA_1 are connected to the inverting input and output terminals of the operational amplifier AMP_2, respectively. Thus, when there is a stable voltage input to the non-inverting input terminal of the operational amplifier AMP_2, the transimpedance circuit 1 can amplify the current signal input to the inverting input terminal of the operational amplifier AMP_2. Since the inverting input terminal of the operational amplifier AMP_2 is connected to the working electrode W1 in electrode group 1, and the output terminal of the operational amplifier AMP_2 is connected to an ADC, the transimpedance circuit 1 can amplify the current signal conducted through the working electrode W1 and transmit the amplified current signal to the ADC.
[0277] The potentiostat circuit 2 may include a digital-to-analog converter module DAC2, operational amplifier AMP_5, and operational amplifier AMP_6. DAC2 generates a stable voltage signal. DAC2 can be connected to the non-inverting input of operational amplifier AMP_5 and also to the non-inverting input of operational amplifier AMP_6, providing the same voltage input to both operational amplifiers AMP_5 and AMP_6. The output of operational amplifier AMP_5 can be connected to the counter electrode C2 in electrode group 2, and the inverting input of operational amplifier AMP_5 can be connected to the reference electrode R2 in electrode group 2. The inverting input of operational amplifier AMP_6 can be connected to the working electrode W2 in electrode group 2, and the output of operational amplifier AMP_6 can be connected to the ADC. Thus, by applying the same voltage to the non-inverting inputs of operational amplifiers AMP_5 and AMP_6, the voltage difference between the reference electrode R2 and the working electrode W2 can be controlled, making the voltage on the working electrode W2 approximately equal to the voltage on the reference electrode R2. It should be noted that in some embodiments, the potentiostat circuit 2 may share a digital-to-analog converter module DAC1 with the potentiostat circuit 1. In this case, the digital-to-analog converter module DAC2 in the potentiostat circuit 2 may also be replaced by the digital-to-analog converter module DAC1. This application does not limit this.
[0278] The transimpedance circuit 2 may include an operational amplifier AMP_6 and a resistor RTIA_2. The two ends of the resistor RTIA_2 are connected to the inverting input and output terminals of the operational amplifier AMP_6, respectively. Thus, when there is a stable voltage input to the non-inverting input terminal of the operational amplifier AMP_6, the transimpedance circuit 2 can amplify the current signal input to the inverting input terminal of the operational amplifier AMP_6. Since the inverting input terminal of the operational amplifier AMP_6 is connected to the working electrode W2 in electrode group 2, and the output terminal of the operational amplifier AMP_6 is connected to an ADC, the transimpedance circuit 2 can amplify the current signal conducted through the working electrode W2 and transmit the amplified current signal to the ADC.
[0279] The amplification module may include an instrumentation amplifier IA, which can be a component integrated from multiple operational amplifiers. The instrumentation amplifier IA may include a non-inverting input, an inverting input, and an output. The instrumentation amplifier IA performs differential operations on the signals from the non-inverting and inverting inputs, amplifying the differential-mode signal between them. Simultaneously, the instrumentation amplifier IA only acts as a follower for the common-mode signal, thereby increasing the ratio between the amplitudes of the differential-mode and common-mode signals and suppressing common-mode signals. The non-inverting input of the instrumentation amplifier IA can be connected to the reference electrode R1 in electrode group 1, and the inverting input can be connected to the working electrode W2 in electrode group 2. In this case, the reference electrode R1 can be considered as the LA electrode, and the working electrode W2 can be considered as the RA electrode. Thus, the instrumentation amplifier IA can amplify the potential difference between the LA and RA electrodes and transmit the amplified ECG signal to the filtering circuit.
[0280] In some embodiments, the right leg drive circuit may include an operational amplifier AMP_3, multiple resistors, and a capacitor C1. The multiple resistors may include resistors R1, R2, R3, and R4. The non-inverting input of operational amplifier AMP_3 can be connected to a voltage source VCM_REF, which can apply a stable voltage to operational amplifier AMP_3. The inverting input of operational amplifier AMP_3 can be connected to instrumentation amplifier IA via resistor R2 to receive the common-mode signal output by instrumentation amplifier IA. Furthermore, the output of operational amplifier AMP_3 can be connected to the counter electrode C2 in electrode group 2 via resistor R1; in this case, counter electrode C2 can be considered as the RLD electrode. The two ends of resistor R3 can be connected to the output and inverting input of operational amplifier AMP_3, respectively. The two ends of resistor R4 are connected to capacitor C1 and the output of operational amplifier AMP_3, respectively. The two ends of capacitor C1 are connected to resistor R4 and the inverting input of operational amplifier AMP_3, respectively. That is, resistor R4 and capacitor C1 are connected in series, and the branch formed by the series connection of resistor R4 and capacitor C1 is connected in parallel with resistor R3. The right leg drive circuit can apply an inverted signal of the common-mode signal through the RLD electrode, thereby canceling the common-mode signal.
[0281] The filtering circuit may include multiple filters, such as filter1 and filter2, and optionally, an operational amplifier AMP_4. In some embodiments, filter1 may be connected to the output of instrumentation amplifier IA and the input of operational amplifier AMP_4, and filter2 may be connected to the output of operational amplifier AMP_4 and the input of ADC. The filtering circuit can receive the amplified ECG signal sent by the amplification circuit, perform one or more operations such as filtering and amplification on the amplified ECG signal, and send the processed ECG signal to ADC.
[0282] The DFT module is optional. The DFT can process the digital signal transmitted by the ADC and then transmit it to the MCU.
[0283] The specific functions of the ADC, MCU, and temperature module temp can be found in the descriptions in the embodiments shown in Figure 4A or Figure 4B above, and will not be repeated here.
[0284] It should be noted that in the embodiment shown in FIG4C, electrode group 1 and electrode group 2 can be electrode group 1 and electrode group 2 in the embodiments shown in FIG3A-FIG3B or FIG3D-FIG3E.
[0285] It is understood that the embodiment shown in Figure 4C above is only an example. In the embodiments of this application, the measurement circuit may also include more electrode groups, potentiostat circuits, and transimpedance circuits for measuring more physiological parameters, and this application does not limit the scope of the invention. In addition, each circuit module of the measurement circuit may include more, fewer, or different elements than those in the above embodiments, and this application does not limit the scope of the invention.
[0286] Figure 4D shows a circuit diagram of another measurement circuit provided in an embodiment of this application.
[0287] As shown in Figure 4D, the measurement circuit may include a potentiostat circuit 1, a transimpedance circuit 1, a potentiostat circuit 2, a transimpedance circuit 2, a right leg drive circuit, an amplifier circuit, a filter circuit, an analog-to-digital converter (ADC) module, and an MCU, etc. Optionally, the measurement circuit may also include one or more of the following: a Discrete Fourier Transform (DFT) module and a temperature module (temp), etc. Furthermore, the measurement circuit may include multiple electrode groups, such as electrode group 1 and electrode group 2. Electrode group 1 may include one or more working electrodes W1, one or more reference electrodes R1, and one or more counter electrodes C1. In addition, electrode group 1 may also include an LA electrode. Electrode group 2 may include one or more working electrodes W2, one or more reference electrodes R2, and one or more counter electrodes C2. In addition, electrode group 2 may also include an RA electrode and an RLD electrode.
[0288] The connection relationships between each electrode in electrode group 1 and electrode group 2 and other circuit components are described below.
[0289] In electrode group 1, one or more counter electrodes C1 can be connected to the output terminal of operational amplifier AMP_1; one or more reference electrodes R1 can be connected to the inverting input terminal of operational amplifier AMP_1; one or more working electrodes W1 can be connected to the inverting input terminal of operational amplifier AMP_2; and the LA electrode can be connected to the non-inverting input terminal of instrumentation amplifier IA. Operational amplifiers AMP_1 and AMP_2 belong to potentiostat circuit 1, and instrumentation amplifier IA belongs to the amplification circuit.
[0290] In electrode group 2, one or more counter electrodes C2 can be connected to the output terminal of operational amplifier AMP_5; one or more reference electrodes R2 can be connected to the inverting input terminal of operational amplifier AMP_5; one or more working electrodes W2 can be connected to the inverting input terminal of operational amplifier AMP_6; electrode RA can be connected to the inverting input terminal of instrumentation amplifier IA; and electrode RLD can be connected to the output terminal of operational amplifier AMP_3 through resistor R1. Operational amplifiers AMP_5 and AMP_6 belong to potentiostat circuit 2, instrumentation amplifier IA belongs to the amplification circuit, and operational amplifier AMP_3 and resistor R1 belong to the right leg drive circuit.
[0291] It should be noted that in electrode group 1 or electrode group 2, the one or more electrodes with the same function can be connected to external components in parallel. For specific connection methods, please refer to the relevant content in the embodiment shown in Figure 4E below, which will not be described in detail here.
[0292] Furthermore, the specific contents of potentiostat circuit 1, transimpedance circuit 1, potentiostat circuit 2, transimpedance circuit 2, right leg drive circuit, amplifier circuit, filter circuit, MCU, ADC, DFT, and temperature module temp can be referred to the relevant contents in the embodiment shown in Figure 4C above, and will not be repeated here.
[0293] In the embodiment shown in FIG4D, electrode group 1 and electrode group 2 can be the electrode group 1 and electrode group 2 in the embodiments shown in FIG3A-FIG3B or FIG3D-FIG3E.
[0294] It is understood that the embodiment shown in Figure 4D above is only an example. In the embodiments of this application, the measurement circuit may also include more electrode groups, potentiostat circuits, and transimpedance circuits for measuring more physiological parameters, and this application does not limit the scope of the invention. In addition, each circuit module of the measurement circuit may include more, fewer, or different elements than those in the above embodiments, and this application does not limit the scope of the invention.
[0295] Using the measurement circuit shown in Figure 4C or Figure 4D, multiple physiological parameters and the user's electrocardiogram signal can be measured simultaneously.
[0296] Figure 4E shows a schematic diagram of the connection between one or more electrodes with the same function and other components in the circuit of an array sensor 1 provided in an embodiment of this application.
[0297] As shown in Figure 4E, the array sensor 1 may include one or more working electrodes W1, one or more reference electrodes R1, one or more counter electrodes C1, and an LA electrode. Specifically, the one or more working electrodes W1 may include working electrodes W11, W12, and W13; the one or more reference electrodes R1 may include reference electrodes R11, R12, and R13; and the one or more counter electrodes C1 may include counter electrodes C11, C12, and C13.
[0298] Taking the array sensor 1, which includes the electrode group 1 shown in Figure 4D, as an example, the working electrodes W11, W12, and W13 can be connected in parallel to the same port, such as the inverting input terminal of the operational amplifier AMP_2 in the embodiment shown in Figure 4D. The reference electrodes R11, R12, and R13 can also be connected in parallel to the same port, such as the inverting input terminal of the operational amplifier AMP_1 in the embodiment shown in Figure 4D. The counter electrodes C11, C12, and C13 can also be connected in parallel to the same port, such as the output terminal of the operational amplifier AMP_1 shown in Figure 4D.
[0299] It is understood that the embodiment shown in Figure 4E above is merely an illustrative example illustrating that electrodes with the same function in an array sensor can be connected in parallel to the same port of the same element in the measurement circuit. In this embodiment, the number of electrodes with different functions in the array sensor 1 may also be different from the above embodiment, and other array sensors or microneedle sensors (e.g., microneedle sensors with multiple electrochemical electrodes of the same type) may also be connected to the elements in the measurement circuit in the manner shown in the above embodiment. This application does not limit this.
[0300] In one possible implementation, multiple electrode groups in the measurement circuit can share a single electrochemical circuit module (including a potentiostat circuit and a transresistance circuit). In this case, the measurement circuit may also include a switching switch, which can be used to control the electrochemical circuit module to connect electrode group 1 or electrode group 2.
[0301] Figure 4F shows a circuit diagram of another measurement circuit provided in an embodiment of this application.
[0302] As shown in Figure 4F, the measurement circuit may include a switching switch MUX0, a potentiostat circuit 1, a transimpedance circuit 1, a right leg drive circuit, an amplifier circuit, a filter circuit, an analog-to-digital converter (ADC) module, and an MCU, etc. Optionally, the measurement circuit may also include one or more of the following: a Discrete Fourier Transform (DFT) module and a temperature module temp, etc. Furthermore, the measurement circuit may include multiple electrode groups, such as electrode group 1 and electrode group 2. Electrode group 1 may include a working electrode W1, a reference electrode R1, and a counter electrode C1; electrode group 2 may include a working electrode W2, a reference electrode R2, and a counter electrode C2.
[0303] The toggle switch MUX0 may include multiple input terminals, such as input terminals A01, A02, A03, B01, B02, and B03; the toggle switch MUX0 may also include multiple output terminals, such as output terminals Y01, Y02, and Y03. Each output terminal of the toggle switch MUX0 can correspond to multiple input terminals. Specifically, output terminal Y01 can correspond to input terminals A01 and B01, output terminal Y02 can correspond to input terminals A02 and B02, and output terminal Y03 can correspond to input terminals A03 and B03. MUX0 can control an output terminal to connect to one of its corresponding input terminals, for example, controlling output terminal Y01 to connect to input terminal A01 or B01, controlling output terminal Y02 to connect to input terminal A02 or B02, and controlling output terminal Y03 to connect to input terminal A03 or B03.
[0304] Output terminal Y01 can be connected to the output terminal of operational amplifier AMP_1, output terminal Y02 can be connected to the inverting input terminal of operational amplifier AMP_1, and output terminal Y03 can be connected to the inverting input terminal of operational amplifier AMP_2. Operational amplifiers AMP_1 and AMP_2 belong to potentiostat circuit 1.
[0305] Input terminal A01 can be connected to the counter electrode C2, input terminal A02 can be connected to the reference electrode R2, and input terminal A03 can be connected to the working electrode W2. Input terminal B01 can be connected to the counter electrode C1, input terminal B02 can be connected to the reference electrode R1, and input terminal B03 can be connected to the working electrode W1.
[0306] When the switch MUX0 is selected to connect input terminals A01, A02, and A03, the potentiostat circuit 1 and the cross-group circuit 1 can be connected to the electrochemical electrode in the electrode group 2 through the switch MUX0; when the switch MUX0 is selected to connect input terminals B01, B02, and B03, the potentiostat circuit 1 and the cross-group circuit 1 can be connected to the electrochemical electrode in the electrode group 1 through the switch MUX0.
[0307] Furthermore, in electrode group 2, the counter electrode C2 can also serve as the RLD electrode, connected to the output terminal of operational amplifier AMP_3 via resistor R1, and the working electrode W2 can also serve as the RA electrode, connected to the inverting input terminal of instrumentation amplifier IA. In electrode group 1, the reference electrode R1 can also serve as the LA electrode, connected to the non-inverting input terminal of instrumentation amplifier IA. Instrumentation amplifier IA is an amplification circuit, while resistor R1 and operational amplifier AMP_3 constitute the right leg drive circuit.
[0308] Furthermore, the composition and connection methods of other components in circuits such as potentiostat circuit 1, transimpedance circuit 1, potentiostat circuit 2, transimpedance circuit 2, right leg drive circuit, amplifier circuit, and filter circuit can be referred to the relevant descriptions in the embodiment shown in Figure 4C above, and will not be repeated here. Moreover, the specific details of the MCU, ADC, DFT, and temperature module temp can be referred to the relevant content in the embodiment shown in Figure 4C above, and will not be repeated here.
[0309] It is understood that the embodiment shown in Figure 4F above is only an example. In the embodiments of this application, the measurement circuit may also include more electrode groups, potentiostat circuits, and transimpedance circuits. The switching switch may also include more input terminals and output terminals, or it may include more switching switches to control the measurement of more physiological parameters. This application does not limit this. In addition, each circuit module of the measurement circuit may also include more, fewer, or different elements than those in the above embodiments. This application does not limit this.
[0310] Figure 4G shows a circuit diagram of another measurement circuit provided in an embodiment of this application.
[0311] As shown in Figure 4G, the measurement circuit may include a switching switch MUX0, a potentiostat circuit 1, a transimpedance circuit 1, a right leg drive circuit, an amplifier circuit, a filter circuit, an analog-to-digital converter (ADC) module, and an MCU, etc. Optionally, the measurement circuit may also include one or more of the following: a Discrete Fourier Transform (DFT) module and a temperature module temp, etc. Furthermore, the measurement circuit may include multiple electrode groups, such as electrode group 1 and electrode group 2. Electrode group 1 may include one or more working electrodes W1, one or more reference electrodes R1, and one or more counter electrodes C1. Electrode group 1 may also include an LA electrode. Electrode group 2 may include one or more working electrodes W2, one or more reference electrodes R2, and one or more counter electrodes C2. Electrode group 2 may also include an RA electrode and an RLD electrode.
[0312] The switching switch MUX0 may include multiple input terminals and output terminals, and each output terminal may correspond to multiple input terminals. The correspondence between the input terminals and output terminals of the switching switch MUX0, as well as the connection relationships between the input terminals, output terminals, and other components or electrodes, can be referred to the relevant descriptions in the embodiment shown in Figure 4F above, and will not be repeated here. It should be noted that the connection methods between each electrochemical electrode in electrode group 1 and electrode group 2 and the switching switch MUX0 can be referred to the relevant content in the embodiments shown in Figures 4E and 4F above.
[0313] When the switch MUX0 is selected to connect input terminals A01, A02, and A03, the potentiostat circuit 1 and the cross-group circuit 1 can be connected to the electrochemical electrode in the electrode group 2 through the switch MUX0; when the switch MUX0 is selected to connect input terminals B01, B02, and B03, the potentiostat circuit 1 and the cross-group circuit 1 can be connected to the electrochemical electrode in the electrode group 1 through the switch MUX0.
[0314] Furthermore, in electrode group 2, the RLD electrode is connected to the output of operational amplifier AMP_3 via resistor R1, and the RA electrode can be connected to the inverting input of instrumentation amplifier IA. In electrode group 1, the LA electrode can be connected to the non-inverting input of instrumentation amplifier IA. Instrumentation amplifier IA is an amplification circuit, and resistor R1 and operational amplifier AMP_3 constitute the right leg drive circuit.
[0315] Furthermore, the composition and connection methods of other components in circuits such as potentiostat circuit 1, transimpedance circuit 1, potentiostat circuit 2, transimpedance circuit 2, right leg drive circuit, amplifier circuit, and filter circuit can be referred to the relevant descriptions in the embodiment shown in Figure 4C above, and will not be repeated here. Moreover, the specific details of the MCU, ADC, DFT, and temperature module temp can be referred to the relevant content in the embodiment shown in Figure 4C above, and will not be repeated here.
[0316] It is understood that the embodiment shown in Figure 4G above is only an example. In the embodiments of this application, the measurement circuit may also include more electrode groups, potentiostat circuits, and transimpedance circuits. The switching switch may also include more input terminals and output terminals, or it may include more switching switches to control the measurement of more physiological parameters. This application does not limit this. In addition, each circuit module of the measurement circuit may also include more, fewer, or different elements than those in the above embodiments. This application does not limit this.
[0317] Using the measurement circuit shown in Figure 4F or Figure 4G, another physiological signal can be measured simultaneously by switching on a switch.
[0318] In another possible implementation, the electrochemical circuit module and the electrocardiogram circuit module in the measurement circuit can share one or more components (e.g., operational amplifiers, filters, etc.). The measurement circuit can also include multiple switching switches, which can be used to control the one or more components to measure electrocardiogram signals or other physiological parameters.
[0319] Figure 4H shows a circuit diagram of a measurement circuit provided in an embodiment of this application.
[0320] As shown in Figure 4H, the measurement circuit may include multiple switching switches, a potentiostat circuit 0, a transimpedance circuit 0, a right leg drive circuit, an amplifier circuit, a filter circuit, an analog-to-digital converter (ADC) module, and an MCU, etc. Optionally, the measurement circuit may also include one or more of the following: a Discrete Fourier Transform (DFT) module and a temperature module temp, etc. Furthermore, the measurement circuit may include multiple electrode groups, such as electrode group 1 and electrode group 2. Electrode group 1 may include a working electrode W1, a reference electrode R1, and a counter electrode C1; electrode group 2 may include a working electrode W2, a reference electrode R2, and a counter electrode C2.
[0321] The multiple switches may include switch MUX1, switch MUX2, and switch MUX3. Switch MUX1 can be used to control the connection of the microneedle sensor between potentiostat circuit 0 and transresistance circuit 0. Switches MUX2 and MUX3 can be used to control the measurement circuit to measure electrocardiogram signals or other physiological parameters.
[0322] The following sections describe the ports of the multiple toggle switches and the connection methods for each port.
[0323] The toggle switch MUX1 may include multiple input terminals, such as input terminals A11, A12, A13, B11, B12, and B13; the toggle switch MUX1 may also include multiple output terminals, such as output terminals Y11, Y12, and Y13. Each output terminal of the toggle switch MUX1 may correspond to multiple input terminals, and MUX1 can control the output terminal to connect to one of the input terminals corresponding to that output terminal. Specifically, output terminal Y11 may correspond to input terminals A11 and B11, output terminal Y12 may correspond to input terminals A12 and B12, and output terminal Y13 may correspond to input terminals A13 and B13.
[0324] Output terminal Y11 can be connected to the output terminal of operational amplifier AMP_7. Output terminal Y12 can be connected to the input terminal B22 of switch MUX2. Output terminal Y12 can also be connected to the input terminal A31 of switch MUX3. Output terminal Y12 can also be connected to the non-inverting input terminal of instrumentation amplifier IA through resistor R6. Output terminal Y12 can also be connected to the LA electrode (e.g., the reference electrode R1 in electrode group 1). Output terminal Y13 can be connected to the input terminal A32 of switch MUX3.
[0325] Input terminal A11 can be connected to the counter electrode C2, input terminal A12 can be connected to the reference electrode R2, and input terminal A13 can be connected to the working electrode W2. Input terminal B11 can be connected to the counter electrode C1, input terminal B12 can be connected to the reference electrode R1, and input terminal B13 can be connected to the working electrode W1.
[0326] When the switch MUX1 is selected to connect input terminals A11, A12, and A13, the potentiostat circuit 0 and the cross-group circuit 0 can be connected to the electrochemical electrode in electrode group 2 through the switch MUX1; when the switch MUX1 is selected to connect input terminals B11, B12, and B13, the potentiostat circuit 0 and the cross-group circuit 0 can be connected to the electrochemical electrode in electrode group 1 through the switch MUX1.
[0327] The toggle switch MUX2 may include multiple input terminals, such as input terminals A21, A22, B21, and B22; the toggle switch MUX2 may also include multiple output terminals, such as output terminals Y21 and Y22. Each output terminal of the toggle switch MUX2 can correspond to multiple input terminals, and MUX2 can control the output terminal to connect to one of the input terminals corresponding to that output terminal. Specifically, output terminal Y21 can correspond to input terminals A21 and B21, and output terminal Y22 can correspond to input terminals A22 and B22.
[0328] Output Y21 can be connected to the non-inverting input of operational amplifier AMP_7, and output Y22 can be connected to the non-inverting input of operational amplifier AMP_8.
[0329] Input terminal A21 and input terminal A22 can be connected to the digital-to-analog converter module DAC0. Input terminal B21 can be connected to the working electrode W2 in electrode group 2, and input terminal B21 can also be connected to the non-inverting input terminal of instrumentation amplifier IA through resistor R5. Input terminal B22 can be connected to the LA electrode (i.e., the reference electrode R1 in electrode group 1), and input terminal B22 can also be connected to the output terminal Y12 of switch MUX1 and the input terminal A31 of switch MUX3. Input terminal B22 can also be connected to the non-inverting input terminal of instrumentation amplifier IA through resistor R6.
[0330] The toggle switch MUX3 may include multiple input terminals, such as input terminals A31, A32, B31, and B32; the toggle switch MUX3 may also include multiple output terminals, such as output terminals Y31 and Y32. Each output terminal of the toggle switch MUX3 can correspond to multiple input terminals, and the MUX3 can control the output terminal to connect to one of the input terminals corresponding to that output terminal. Specifically, output terminal Y31 can correspond to input terminals A31 and B31, and output terminal Y32 can correspond to input terminals A32 and B32.
[0331] Output terminal Y31 can be connected to the inverting input terminal of operational amplifier AMP_7, and output terminal Y32 can be connected to the inverting input terminal of operational amplifier AMP_8. Operational amplifiers AMP_7 and AMP_8 belong to the potentiostat circuit 0.
[0332] Input terminal A31 can be connected to the output terminal Y12 of switch MUX1 and the input terminal B22 of switch MUX2. Input terminal A32 can be connected to the output terminal Y13 of switch MUX1, and can also be connected to the output terminal of operational amplifier AMP_8 through resistor RTIA_0. Input terminal B31 can be connected to the output terminal of instrumentation amplifier IA, and can also be connected to the inverting input terminal of operational amplifier AMP_3 through resistor R2. Input terminal B32 can be connected to input terminal B31, meaning that the inputs of input terminals B31 and B32 are the same.
[0333] When switch MUX2 is selected to connect input terminals A21 and A22, and switch MUX3 is selected to connect input terminals A31 and A32, the measurement circuit can measure the user's physiological parameters (such as blood glucose, blood ketones, etc.); when MUX2 is selected to connect input terminals B21 and B22, and switch MUX3 is selected to connect input terminals B31 and B32, the measurement circuit can measure electrocardiogram (ECG) signals.
[0334] The potentiostat circuit 0 may include a digital-to-analog converter module DAC0, operational amplifiers AMP_7 and AMP_8, and switches MUX2 and MUX3. The connection methods of each component can be referred to the relevant descriptions of switches MUX2 and MUX3 above, and the functional descriptions of other components can be referred to the relevant descriptions in the above embodiments, and will not be repeated here. Furthermore, the output terminal of operational amplifier AMP_7 can be connected to filter1, and the output terminal of operational amplifier AMP_8 can be connected to filter2.
[0335] The cross-group circuit 0 may include an operational amplifier AMP_8, a resistor RTIA_0, and a switching switch MUX3. The connection methods of each component can be referred to the relevant descriptions of switching switches MUX2 and MUX3 above, and the functional descriptions of other components can be referred to the relevant descriptions in the above embodiments, and will not be repeated here.
[0336] The amplifier circuit may include an instrumentation amplifier IA, and may also include resistors R5 and R6. Resistor R6 connects the LA electrode (i.e., the reference electrode R1) to the non-inverting input of instrumentation amplifier IA, and resistor R5 connects the RA electrode (i.e., the working electrode W2) to the non-inverting input of instrumentation amplifier IA. The inverting input of instrumentation amplifier IA can be connected to its output. Other connections of instrumentation amplifier IA can be found in the descriptions of other components and will not be repeated here.
[0337] The component composition and connection relationships between the components in the right leg drive circuit can be referred to the relevant description in the embodiment shown in Figure 4C above. Furthermore, the inverting input of operational amplifier AMP_3 can also be connected to the output of instrumentation amplifier IA, and the inputs B31 and B32 of switch MUX3 via resistor R2.
[0338] The filtering circuit may include filter1 and filter2. The filtering circuit can be used to filter the signals output from operational amplifiers AMP_7 and AMP_8.
[0339] The specific functional descriptions of each module in the measurement circuit can be found in the relevant descriptions in the embodiment shown in Figure 4C above, and will not be repeated here.
[0340] It is understood that the embodiment shown in Figure 4H above is only an example. In the embodiments of this application, the measurement circuit may also include more electrode groups, potentiostat circuits, and transimpedance circuits. The switching switch may also include more input terminals and output terminals, or it may include more switching switches to control the measurement of more physiological parameters. This application does not limit this. In addition, each circuit module of the measurement circuit may also include more, fewer, or different elements than those in the above embodiments. This application does not limit this.
[0341] Figure 4I shows a circuit diagram of another measurement circuit provided in an embodiment of this application.
[0342] As shown in Figure 4I, the measurement circuit may include multiple switching switches, a potentiostat circuit 0, a transimpedance circuit 0, a right leg drive circuit, an amplifier circuit, a filter circuit, an analog-to-digital converter (ADC) module, and an MCU, etc. Optionally, the measurement circuit may also include one or more of the following: a Discrete Fourier Transform (DFT) module and a temperature module temp, etc. Furthermore, the measurement circuit may include multiple electrode groups, such as electrode group 1 and electrode group 2. Electrode group 1 may include one or more working electrodes W1, one or more reference electrodes R1, and one or more counter electrodes C1. Electrode group 1 may also include an LA electrode. Electrode group 2 may include one or more working electrodes W2, one or more reference electrodes R2, and one or more counter electrodes C2. Electrode group 2 may also include an RA electrode and an RLD electrode.
[0343] The multiple switches may include switch MUX1, switch MUX2, and switch MUX3. Switch MUX1 can be used to control the potentiostat circuit 0 and the transimpedance circuit 0 to connect electrode group 1 or electrode group 2. Switches MUX2 and MUX3 can be used to control the measurement circuit to measure electrocardiogram signals or other physiological parameters.
[0344] The following describes the connection relationship between each electrode in electrode group 1 and electrode group 2 and the measurement circuit.
[0345] In electrode group 1, the one or more working electrodes W1 can be connected to the input terminal B13 of the switching switch MUX1, the one or more reference electrodes R1 can be connected to the input terminal B12 of the switching switch MUX1, the one or more counter electrodes C1 can be connected to the input terminal B11 of the switching switch MUX1, the LA electrode can be connected to the non-inverting input terminal of the instrumentation amplifier IA through resistor R6, and the LA electrode can also be connected to the output terminal Y12 of the switching switch MUX1.
[0346] In electrode group 2, one or more working electrodes W2 can be connected to the input terminal A13 of switch MUX1, one or more reference electrodes R2 can be connected to the input terminal A12 of switch MUX1, one or more counter electrodes C2 can be connected to the input terminal A11 of switch MUX1, electrode RA can be connected to the non-inverting input terminal of instrumentation amplifier IA through resistor R5, and electrode RA can also be connected to the input terminal B21 of switch MUX2. Electrode RLD can be connected to the output terminal of operational amplifier AMP_3 through resistor R1.
[0347] When the switch MUX1 is selected to connect input terminals A11, A12, and A13, the potentiostat circuit 0 and the cross-group circuit 0 can be connected to the electrochemical electrode in electrode group 2 through the switch MUX1; when the switch MUX1 is selected to connect input terminals B11, B12, and B13, the potentiostat circuit 0 and the cross-group circuit 0 can be connected to the electrochemical electrode in electrode group 1 through the switch MUX1.
[0348] When switch MUX2 is selected to connect input terminals A21 and A22, and switch MUX3 is selected to connect input terminals A31 and A32, the measurement circuit can measure the user's physiological parameters (such as blood glucose, blood ketones, etc.); when MUX2 is selected to connect input terminals B21 and B22, and switch MUX3 is selected to connect input terminals B31, B32, and B33, the measurement circuit can measure electrocardiogram (ECG) signals.
[0349] The specific functional descriptions of each module in the measurement circuit can be found in the relevant descriptions in the embodiment shown in Figure 4H above, and will not be repeated here.
[0350] It is understood that the embodiment shown in Figure 4I above is only an example. In the embodiments of this application, the measurement circuit may also include more electrode groups, potentiostat circuits, and transimpedance circuits. The switching switch may also include more input terminals and output terminals, or it may include more switching switches to control the measurement of more physiological parameters. This application does not limit this. In addition, each circuit module of the measurement circuit may also include more, fewer, or different elements than those in the above embodiments. This application does not limit this.
[0351] Using the measurement circuit shown in Figure 4H or Figure 4I, the measurement of electrocardiogram signals can be controlled by a switching switch, or physiological parameters can be measured through electrochemical electrodes.
[0352] In another possible implementation, the measurement circuit may include three or more electrochemical circuit modules, and the multiple working electrodes in the electrode group can be connected to different electrochemical circuit modules to measure different physiological parameters. In this way, three or more physiological parameters can be measured simultaneously, and electrocardiogram signals can also be measured simultaneously.
[0353] For example, as shown in Figure 4J, the measurement circuit may include a potentiostat circuit 1, a transimpedance circuit 1, a potentiostat circuit 2, a transimpedance circuit 2, a potentiostat circuit 3, a right leg drive circuit, an amplifier circuit, a filter circuit, an analog-to-digital converter (ADC) module, and an MCU, etc. Optionally, the measurement circuit may also include one or more of the following: a Discrete Fourier Transform (DFT) module and a temperature module (temp), etc. Moreover, the measurement circuit may also include multiple electrode groups, such as electrode group 1 and electrode group 2. Electrode group 1 may include one or more working electrodes W1, one or more reference electrodes R1, and one or more counter electrodes C1. In addition, electrode group 1 may also include an LA electrode. Electrode group 2 may include working electrodes W21 and W22, reference electrodes R21 and R22, counter electrodes C21 and C22. In addition, electrode group 2 may also include an RA electrode and an RLD electrode.
[0354] The internal components and connections of the potentiostat circuit 1, transimpedance circuit 1, potentiostat circuit 2, transimpedance circuit 2, right leg drive circuit, amplifier circuit, and filter circuit can be found in the descriptions in the embodiment shown in Figure 4D above, and will not be repeated here. The functional descriptions of the analog-to-digital converter (ADC), discrete Fourier transform (DFT), and MCU can also be found in the descriptions in the embodiment shown in Figure 4D above.
[0355] The potentiostat circuit 3 may include operational amplifiers AMP_9 and AMP_10, and a digital-to-analog converter (DAC) module DAC3. In some embodiments, DAC3 may be replaced by DAC1 in potentiostat circuit 1, or DAC2 in potentiostat circuit 2; this application does not limit the specific implementation. DAC3 can generate a stable voltage signal. DAC3 can be connected to the non-inverting input of operational amplifier AMP_9 and also to the non-inverting input of operational amplifier AMP_10, providing the same voltage input for both operational amplifiers AMP_9 and AMP_10. The output of operational amplifier AMP_9 can be connected to the counter electrode C21 in electrode group 2, and the inverting input of operational amplifier AMP_9 can be connected to the reference electrode R21 in electrode group 2. The inverting input of operational amplifier AMP_10 can be connected to the working electrode W21 in electrode group 2, and the output of operational amplifier AMP_10 can be connected to the ADC. In this way, by applying the same voltage to the non-inverting input terminals of operational amplifiers AMP_9 and AMP_10, the voltage difference between the reference electrode R21 and the working electrode W21 can be controlled, so that the voltage on the working electrode W21 is approximately equal to the voltage on the reference electrode R21.
[0356] The transimpedance circuit 3 may include an operational amplifier AMP_10 and a resistor RTIA_3. The two ends of the resistor RTIA_3 can be connected to the inverting input and output terminals of the operational amplifier AMP_10, respectively. The inverting input terminal of the operational amplifier AMP_10 can also be connected to the working electrode W21 in the electrode group 2.
[0357] The components and connections between the components in potentiostat circuit 2 and transimpedance circuit 2 can be found in the descriptions in the embodiment shown in Figure 4D above.
[0358] The connection relationships between the potentiostat circuit 2 and the multiple electrodes in electrode group 2 are as follows: the output terminal of operational amplifier AMP_5 can be connected to the counter electrode C22 in electrode group 2, and the inverting input terminal of operational amplifier AMP_5 can be connected to the reference electrode R22 in electrode group 2. The inverting input terminal of operational amplifier AMP_6 can be connected to the working electrode W22 in electrode group 2, and the output terminal of operational amplifier AMP_6 can be connected to the ADC. Thus, by applying the same voltage to the non-inverting input terminals of operational amplifiers AMP_5 and AMP_6, the voltage difference between the reference electrode R22 and the working electrode W22 can be controlled, making the voltage on the working electrode W22 approximately equal to the voltage on the reference electrode R22.
[0359] The connection relationship between the transimpedance circuit 2 and the multiple electrodes in the electrode group 2 is as follows: The inverting input terminal of the operational amplifier AMP_6 can also be connected to the working electrode W22 in the electrode group 2.
[0360] The component composition of other modules in the measurement circuit and the connection relationship between components can be referred to the relevant content in the embodiment shown in Figure 4D above, and will not be repeated here.
[0361] It is understood that the embodiment shown in Figure 4J above is only an illustrative example. Different working electrodes in the electrode group can be connected to different electrochemical circuit modules. In the embodiments of this application, the measurement circuit may also include more or fewer electrochemical circuit modules than in the above embodiments. Multiple working electrodes in electrode group 2 (or electrode group 1) can also be connected to different electrochemical circuit modules to measure different physiological parameters. This application does not limit this.
[0362] In other embodiments, the same reference electrode and / or counter electrode may be connected to different electrochemical circuit modules (e.g., different potentiostat circuits) for measuring multiple different physiological parameters, and this application does not limit this to any particular embodiment.
[0363] It is understood that the embodiments shown in Figures 4C-4J above are merely examples. In the embodiments of this application, the measurement circuit may include more, fewer, or different circuit modules and components than those in the above embodiments, or the connection method between the various components in the measurement circuit may also be different from that in the above embodiments. This application does not impose any limitations here. For example, the measurement circuit (or the circuit module of the measurement circuit) shown in any of the above embodiments may also be provided with one or more circuit switches, which may also be used by the measurement circuit to measure one or more physiological parameters (or electrocardiogram signals). This application does not impose any limitations here.
[0364] It should be noted that electrode group 1 and electrode group 2 in the embodiments shown in Figures 4C-4J can be disposed in a microneedle sensor or in an array sensor. Furthermore, electrode group 1 and electrode group 2 in the embodiments shown in Figures 4C-4J can also employ a dual-electrode system. In a dual-electrode system, the connection method between the counter electrode and the working electrode can be the same as in the above embodiments, and the counter electrode can also simultaneously serve as a reference electrode connected to the port connected to the reference electrode in the above embodiments. This application does not impose any limitations on this.
[0365] The measurement method provided in the embodiments of this application is described below.
[0366] Figure 5A shows a flowchart of a measurement method provided in an embodiment of this application.
[0367] As shown in Figure 5A, the specific procedure of the measurement method may include the following steps:
[0368] S501. Electronic equipment 200 determines that monitoring condition 1 is met and determines physiological parameters 1.
[0369] Monitoring condition 1 may include, but is not limited to, any one or more of the following: receiving information 1 sent by other electronic devices to instruct electronic device 200 to detect physiological parameters 1; detecting that the user is wearing electronic device 200 (i.e., the electrodes of electronic device 200 are implanted in the user's subcutaneous tissue); detecting abnormal electrocardiogram signals.
[0370] For example, electronic device 200 can determine whether it is being worn by a user based on whether the temperature detected by a temperature sensor falls within a preset body temperature range. It is understood that this embodiment is merely an example, and other methods may be used to determine whether electronic device 200 is being worn in this application; this application does not limit such methods.
[0371] Physiological parameter 1 may include, but is not limited to, any one or more of the following: blood glucose, blood ketones, blood lactate, uric acid, etc.
[0372] In one possible implementation, when monitoring condition 1 is determined to be met, the electronic device 200 can measure physiological parameter 1, and stop monitoring after determining physiological parameter 1. In another possible implementation, when monitoring condition 1 is determined to be met, the electronic device 200 can periodically detect physiological parameter 1, for example, determining the value of physiological parameter 1 at the current moment every 10 minutes (or 20 minutes, 30 minutes, etc.). It should be noted that in this case, different physiological parameters may correspond to different monitoring cycles or the same monitoring cycle; this application does not impose any limitations on this.
[0373] The electronic device 200 can obtain the reaction current generated by the reaction with the target substance 1 through the electrochemical electrode corresponding to the physiological parameter 1, and determine the physiological parameter 1 based on the magnitude of the reaction current.
[0374] For example, if physiological parameter 1 is blood glucose, and the electrochemical electrode for measuring blood glucose includes the working electrode 3031, reference electrode 3032, and counter electrode 3033 of the microneedle sensor 303 shown in Figure 3B, then when the microneedle sensor 303 is implanted in subcutaneous tissue, the working electrode 3031 can react with glucose to generate a reaction current. The electronic device 200 can acquire the magnitude of this reaction current and determine the blood glucose value based on the magnitude of the reaction current using a blood glucose calculation model stored in the electronic device 200.
[0375] For example, if physiological parameter 1 is blood glucose, and the electrochemical electrodes for measuring blood glucose include the working electrode group 3073, the reference electrode group 3074, and the counter electrode group 3075 in the array sensor 307 shown in Figure 3D, then when the array sensor 307 is implanted in subcutaneous tissue, the working electrode group 3073 can react with glucose to generate a reaction current. The electronic device 200 can acquire the magnitude of this reaction current and determine the blood glucose value based on the magnitude of the reaction current using a blood glucose calculation model stored in the electronic device 200.
[0376] It is understood that the embodiments described here are only two examples. In the embodiments of this application, physiological parameter 1 may also be other physiological parameters different from blood glucose, or may include multiple physiological parameters. This application does not limit this.
[0377] Optionally, the electronic device 200 can also measure the user's body temperature. In this case, the electronic device 200 can further optionally calibrate the value of physiological parameter 1 based on the user's body temperature.
[0378] S502. Electronic device 200 outputs physiological parameters 1.
[0379] In some embodiments, the electronic device 200 may include (or be connected to) an audio module and / or a display screen. In this case, the electronic device 200 may output physiological parameter 1 by voice broadcast through the audio module or by displaying physiological parameter 1 through the display screen.
[0380] In other embodiments, the electronic device 200 outputs physiological parameter 1, or it may send output information 1 to other electronic devices (such as electronic device 100). The output information 1 may include physiological parameter 1 and can be used to instruct the receiving end to output the physiological parameter 1.
[0381] In some embodiments, while outputting the user's physiological parameter 1 (or after outputting the physiological parameter 1), the electronic device 200 may also output any one or more of the following: evaluation results, value range, user status, historical curves, reference suggestions, etc. The specific descriptions and determination methods of each item can be referred to the relevant descriptions in step S605 shown in Figure 6 below, which will not be detailed here.
[0382] S503. Electronic device 200 determines that monitoring condition 2 is met and acquires electrocardiogram signal.
[0383] It should be noted that there is no limitation on the execution order of step S503 and the above step S501. The electronic device 200 can execute step S501 and step S503 at the same time, or it can execute one step first and then the other step. This application does not limit this.
[0384] Monitoring condition 2 may include, but is not limited to, any one or more of the following: receiving information 2 sent by other electronic devices to instruct electronic device 200 to detect electrocardiogram signals; detecting bio-wearable electronic device 200 (i.e., the electrodes of electronic device 200 are implanted in subcutaneous tissue); detecting abnormal physiological parameter 1, etc.
[0385] Here, "abnormal physiological parameter 1" refers to a value of physiological parameter 1 that does not belong to a preset value range for physiological parameter 1. This value range can be pre-stored by the electronic device 200. For example, the electronic device 200 can start acquiring electrocardiogram (ECG) signals when it detects that the user's blood glucose level exceeds a preset blood glucose value range. It is understood that this embodiment is only an illustrative example illustrating whether to acquire ECG signals can be determined by the value of physiological parameters. In this application embodiment, physiological parameter 1 can also be other physiological parameters different from blood glucose, or it can include multiple physiological parameters. This application does not limit this.
[0386] It should be noted that during the acquisition of electrocardiogram (ECG) signals, the ECG electrodes used to measure these signals can be implanted in subcutaneous tissue. In some embodiments, these ECG electrodes can be electrochemical electrodes in electronic device 200 used to measure other physiological parameters.
[0387] For example, if the electronic device 200 is the electronic device 200 in the embodiment shown in FIG. 3B above, then the ECG electrode can be a portion of the electrochemical electrodes in the microneedle sensor 303 and microneedle sensor 304. For example, the LA electrode can be the reference electrode 3032, the RA electrode can be the working electrode 3041, and the RLD electrode can be the counter electrode 3043. As another example, if the electronic device 200 is the electronic device 200 in the embodiment shown in FIG. 3D above, then the ECG electrode can be the ECG electrode in the array sensor 307 and array sensor 308. For example, the LA electrode can be the LA electrode 3081, the RA electrode can be the RA electrode 3071, and the RLD electrode can be the RLD electrode 3072. It is understood that the embodiments here are only two examples. In the embodiments of this application, when the ECG electrode and the electrochemical electrode share the same electrode, the correspondence between the ECG electrode and the electrochemical electrode can also be different from the above embodiments. This application does not limit this relationship.
[0388] In a bipolar lead system, the electrocardiogram (ECG) signal can refer to the voltage difference between the LA and RA electrodes within a preset time period (e.g., 1 minute, 3 minutes, etc.). When the electronic device 200 uses other lead systems to measure the ECG signal, the ECG signal can also be the voltage difference between other electrodes within a preset time period, and this application does not limit it here.
[0389] For example, Figure 5B shows a waveform diagram of an electrocardiogram signal provided in an embodiment of this application.
[0390] As shown in Figure 5B, a two-dimensional coordinate system can include a horizontal axis and a vertical axis. The horizontal axis can represent time, and the vertical axis can represent voltage. The electrocardiogram (ECG) signal waveform can be represented by curve Q in this two-dimensional coordinate system. According to curve Q, the ECG signal waveform exhibits periodic fluctuations as the heart pumps blood periodically.
[0391] It is understood that the embodiment shown in Figure 5B is only an example. In the embodiments of this application, the waveform of the electrocardiogram signal may also be different from the waveform of the above embodiment. This application does not limit it here.
[0392] S504. Electronic device 200 outputs electrocardiogram signal.
[0393] In some embodiments, the electronic device 200 may include (or be connected to) an audio module and / or a display screen. In this case, the electronic device 200 may output the electrocardiogram (ECG) signal by voice broadcast through the audio module or by displaying the ECG signal through the display screen.
[0394] In other embodiments, the electronic device 200 outputs an electrocardiogram (ECG) signal, or it may send output information 2 to other electronic devices (such as electronic device 100). The output information 2 may include the ECG signal, and the output information 2 can be used by the receiving end to output the ECG signal.
[0395] In some embodiments, electronic device 200 (or electronic device 100) may output electrocardiogram (ECG) signals in one or more different forms, such as in the form of a waveform (outputting an ECG), or in the form of ECG indicators.
[0396] In some embodiments, electronic device 200 (or electronic device 100) can determine an electrocardiogram (ECG) based on an ECG signal and display the ECG on a display screen. The ECG can be a waveform diagram of the ECG signal, used to characterize the relationship between the amplitude of the ECG signal and time.
[0397] An electrocardiogram (ECG) can include several different waves, such as the P wave, QRS complex, T wave, and U wave. The following section describes the various waves in an ECG with reference to the ECG shown in Figure 5C.
[0398] As shown in Figure 5C, a two-dimensional coordinate system can include a horizontal axis and a vertical axis. The horizontal axis can represent time, and the vertical axis can represent voltage. The waveform of an electrocardiogram (ECG) signal within a single cardiac cycle can be represented by curve Q0 in this two-dimensional coordinate system.
[0399] As shown in Figure 5C, in curve Q0, the segment from time t1 to t2 can be called the P wave; the segment from time t2 to t3 can be called the QRS complex; the segment from time t3 to t4 can be called the T wave; and the segment from time t4 to t5 can be called the U wave. The point on curve Q0 at time t3 can be called the J point, which represents the end of the QRS complex. Furthermore, the time interval between time t1 and t2 can be called the PR interval, and the time interval between time t2 and t4 can be called the QT interval.
[0400] For example, the amplitude of curve Q0 changes as follows across different time periods: From time t0 to t1, the amplitude of curve Q0 remains stable; from time t1 to t2, the amplitude of curve Q0 first rises to the first peak, then decreases, and then returns to stability, showing a downward trend at time t2; from time t2 to t3, the amplitude of curve Q0 first decreases to the first trough, then rises, rises to the second peak, then decreases, decreases to the second trough, and then rises again; from time t3 to t4, the amplitude of curve Q0 gradually increases after a period of stability, rises to the third peak, and then gradually decreases to the third trough; from time t4 to t5, the amplitude of curve Q0 rises again from the third trough to the fourth peak, then decreases again, and then returns to stability. The amplitude at the second peak is significantly higher than the amplitudes at the other peaks.
[0401] It is understood that the embodiment shown in Figure 5C is only an example. In the embodiments of this application, the electrocardiogram may also include more cycles than the above embodiments, and the waveform in each cycle may also be different from the above embodiments. For example, in some cycles, the P wave may also include two peaks, etc. This application does not limit it here.
[0402] The waves and intervals on an electrocardiogram (ECG) can characterize the health of a user's heart. The P wave represents the depolarization process between the two atria. Because the sinoatrial node is located at the junction of the right atrium and the superior vena cava, excitation from the sinoatrial node is first conducted to the right atrium, then through the interatrial bundle to the left atrium, forming the P wave on the ECG. The P wave represents atrial excitation; the first half represents right atrial excitation, and the second half represents left atrial excitation. When the atria enlarge and conduction between the two atria becomes abnormal, the P wave appears as a tall, peaked or biphasic P wave. The PR interval represents the time from the start of atrial depolarization to the start of ventricular depolarization, mainly reflecting the time it takes for excitation to conduct through the atrioventricular junction. Slow conduction velocity at the atrioventricular node forms the PR segment on the ECG. When conduction from the atria to the ventricles is blocked, it manifests as a prolonged PR interval or the disappearance of the ventricular wave after the P wave. The QRS complex represents the ventricular depolarization process. When conduction block occurs in the left and right bundle branches of the heart, or when the heart is enlarged or hypertrophied, the QRS complex will widen, deform, and prolong its duration. The J point represents the completion of depolarization of all ventricular myocardial cells. The T wave represents two ventricular repolarization processes. Changes in the T wave on an electrocardiogram are influenced by various factors; for example, in myocardial ischemia, the T wave may be flattened and inverted, while a tall T wave can be seen in hyperkalemia, the hyperacute phase of acute myocardial infarction, etc. The U wave can be a waveform following the T wave and is currently believed to be related to ventricular repolarization. The QT interval represents the time required for the entire process of ventricular depolarization and repolarization. Prolongation of the QT interval is often associated with the occurrence of malignant arrhythmias.
[0403] Electronic device 200 can determine one or more electrocardiogram (ECG) parameters based on an ECG signal. Simultaneously with (or after) outputting the ECG signal, electronic device 200 can also output these one or more ECG parameters. ECG parameters may include, but are not limited to, any one or more of the following: heart rate, amplitude, PR interval, QT interval, and the duration of each wave (e.g., P wave duration). Heart rate can be determined based on the number of cardiac cycles per minute in the ECG signal. The PR interval, QT interval, and P wave duration can all be determined based on the ECG (or ECG signal).
[0404] Figure 6 shows a flowchart of another measurement method provided in an embodiment of this application.
[0405] As shown in Figure 6, the specific procedure of the measurement method may include the following steps:
[0406] S601. Electronic device 100 determines that monitoring condition 3 is met and sends information 3 to electronic device 200. Information 3 is used to request electronic device 200 to send physiological data 1 to electronic device 100.
[0407] In some embodiments, monitoring condition 3 may include, but is not limited to, any one or more of the following: receiving an operation from the user to enable the physiological monitoring function, receiving a start command 1 sent by another electronic device, detecting abnormal physiological state of the user (e.g., heart rate not belonging to a preset heart rate range), detecting abnormal psychological state of the user (e.g., being startled), detecting that the user is in a state of exercise, detecting that the user is insomnia, detecting abnormal body posture of the user (e.g., falling), detecting abnormal sports equipment of the user, detecting that the user's location is within a preset area (e.g., the user is in a high-altitude area), etc.
[0408] Physiological data 1 can be used to determine physiological parameter 1, which may include, but is not limited to, any one or more of the following: blood glucose, blood ketones, blood lactate, uric acid, etc.
[0409] Physiological data 1 may include, but is not limited to, any one or more of the following: current data, body temperature, measured value of physiological parameter 1, calibrated value of physiological parameter 1, etc. Among them, current data is used to characterize the magnitude of the reaction current generated when the electrochemical electrode in electronic device 200 reacts with target substance 1. Body temperature may be the body temperature of the user (or other biological entity) wearing electronic device 200. The measured value of physiological parameter 1 may be the value of physiological parameter 1 determined by electronic device 200 based on current data through a calculation model of physiological parameter 1. The calibrated value of physiological parameter 1 may be the value of physiological parameter 1 determined by electronic device 200 based on current data and body temperature, that is, the value of physiological parameter 1 after calibration based on body temperature.
[0410] The following describes the specific method by which electronic device 100 determines whether monitoring condition 3 is met.
[0411] In some embodiments, the electronic device 100 can acquire user information and determine whether the electronic device 100 meets monitoring condition 3 based on the user information. The user information may include, but is not limited to, any one or more of the following: physiological information, psychological information, motion information, sports equipment information, posture information, location information, and interaction information. Physiological information can be used to characterize the user's physiological state, including but not limited to one or more of the following: heart rate, body temperature, blood pressure, disease information, etc.; psychological information can be used to characterize the user's psychological state, including but not limited to one or more of the following: stress level, low mood, stable mood, high mood, being startled, etc.; exercise information can be used to characterize the user's exercise state, including but not limited to one or more of the following: swimming, diving, cycling, running, mountain climbing, rope skipping, yoga, etc.; exercise equipment information can be used to characterize the status of exercise equipment, including but not limited to one or more of the following: remaining oxygen in oxygen cylinders, weight of smart backpacks, resistance of bicycles, etc.; posture information can be used to characterize the user's body posture, including but not limited to one or more of the following: falling, misstepping, remaining still, etc.; location information can be used to characterize the user's location, including but not limited to one or more of the following: the user's geographical location, the latitude and longitude of the user's location, the altitude of the user's location, the depth of the user's location, etc.; interaction information can include the user's interaction with the electronic device 100, such as receiving the user's action to activate the physiological monitoring function, etc.
[0412] It should be noted that, in the embodiments of this application, the electronic device 100 may obtain user information in ways including but not limited to the following: the electronic device 100 detects user information, the electronic device 100 receives user information sent by other electronic devices, and the electronic device 100 receives and obtains user information in response to the user's operation of entering user information (e.g., disease information).
[0413] The following describes some methods by which electronic devices 100 detect user information provided in the embodiments of this application.
[0414] For example, electronic device 100 can detect the user's motion and posture information through devices such as gyroscope sensors and accelerometers; electronic device 100 can detect the user's physiological information such as heart rate and blood pressure through devices such as PPG modules; electronic device 100 can also collect the user's facial expressions through a camera and determine the user's emotional state through image analysis and facial expression analysis algorithms; electronic device 100 can also determine the user's psychological information such as stress level based on physiological information; electronic device 100 can also detect the user's interaction information through touch sensors; electronic device 100 can detect the user's location information through location sensors (such as GPS chips); electronic device 100 can also detect the air pressure of the user's environment based on a barometric pressure sensor and determine the user's location information such as altitude based on the air pressure value, and so on.
[0415] It is understood that the embodiments described herein are merely examples. In the embodiments of this application, the electronic device 100 may include more, fewer, or different devices than those described in the above embodiments. Furthermore, the electronic device 100 may also collect user information through sensors or other devices different from those described in the above embodiments. This application does not impose any limitations on these embodiments.
[0416] The following describes some methods by which electronic devices 100, based on user information, determine whether monitoring condition 3 is met, according to embodiments of this application.
[0417] If the electronic device 100 determines that any physiological information is abnormal, then it determines that the monitoring conditions are met. For example, abnormal physiological information may include, but is not limited to, any one or more of the following: heart rate not falling within a preset heart rate range, blood pressure not falling within a preset blood pressure range, body temperature not falling within a preset body temperature range, etc.
[0418] For example, the electronic device 100 can determine whether the physiological information meets any of the following conditions: the heart rate does not belong to the preset heart rate range, the blood pressure does not belong to the preset blood pressure range, the body temperature does not belong to the preset body temperature range, etc. If the physiological information meets any of the above conditions, the electronic device 100 can determine that the user's physiological state is abnormal, that is, determine that the monitoring conditions are met.
[0419] If the electronic device 100 determines that the motion information meets the preset motion state, then it determines that the monitoring conditions are met. For example, the preset motion state may include, but is not limited to, any one or more of the following: diving, mountain climbing, cycling, yoga, swimming, running, etc.
[0420] If the electronic device 100 determines that the user's psychological state is abnormal based on psychological information, then the monitoring conditions are met. For example, abnormal psychological state includes, but is not limited to, any one or more of the following: the user is frightened, the user is depressed, the user is elated, etc.
[0421] If the electronic device 100 determines that the user is in a preset area based on location information, then the monitoring conditions are met. The preset area may include, but is not limited to, any one or more of the following: high-altitude areas, deep-water areas, etc.
[0422] If the electronic device 100 determines that the user's body posture is abnormal based on the posture information, then the monitoring conditions are met. For example, abnormal user body posture includes, but is not limited to, any one or more of the following situations: the user falls, the user misses a step, etc.
[0423] If the electronic device 100 determines that the user's sports equipment is abnormal based on the sports equipment information, then it determines that the monitoring condition is met. For example, abnormal user sports equipment may include, but is not limited to, any one or more of the following: the remaining oxygen level in the oxygen cylinder is lower than a preset oxygen level, the bicycle's rolling resistance is greater than a preset resistance, the smart backpack's weight is greater than a preset weight, etc. It is understood that the above embodiments are merely illustrative examples of various ways to determine whether monitoring condition 3 is met based on user information. In this application embodiment, the electronic device 100 may also determine whether monitoring condition 3 is met based on various types of user information, and the electronic device 100 may also determine whether monitoring condition 3 is met based on other information in the user information. Furthermore, monitoring condition 3 may include more, fewer, or different conditions than those in the above embodiments, and this application does not limit these conditions.
[0424] S602. Electronic device 200 acquires physiological data 1.
[0425] In some embodiments, electronic device 200 may, in response to information 3, begin acquiring physiological data 1.
[0426] In other embodiments, the electronic device 200 may also periodically acquire physiological data 1 before receiving information 3.
[0427] The method by which electronic device 200 acquires physiological data 1 can be referred to the relevant content of step S501 shown in Figure 5A above, and will not be repeated here.
[0428] S603. Electronic device 200 sends physiological data 1 to electronic device 100.
[0429] In some embodiments, electronic device 200 may send physiological data 1 to electronic device 100 in response to information 3.
[0430] In some embodiments, the electronic device 200 periodically sends physiological data 1 to the electronic device 100 before receiving information 3. In this case, step S602 described above may not be performed; furthermore, monitoring condition 3 may be used to trigger the electronic device 100 to perform step S605 described below.
[0431] S604. Electronic device 100 determines physiological parameters 1 based on physiological data 1.
[0432] In some embodiments, if physiological data 1 includes a measured or calibrated value of physiological parameter 1, the electronic device 100 may use the measured or calibrated value of physiological parameter 1 as the value of physiological parameter 1.
[0433] In some embodiments, if physiological parameter 1 includes the measured value of physiological parameter 1 and body temperature, the electronic device 100 can calibrate the measured value of physiological parameter 1 based on body temperature and determine the calibrated value as the value of physiological parameter 1.
[0434] In some embodiments, if physiological data 1 includes current data, the electronic device 100 can determine the value of physiological parameter 1 based on the current data. Optionally, if physiological data 1 also includes body temperature, the electronic device 100 can also determine the value of physiological parameter 1 based on both current data and body temperature.
[0435] S605. Electronic device 100 outputs physiological parameter 1.
[0436] In some embodiments, after determining the user's physiological parameter 1, the electronic device 100 can output physiological parameter 1. The electronic device 100 may output physiological parameter 1 in the following ways, including but not limited to any one or more of the following: display screen display, voice broadcast, vibration, indicator light flashing, etc. A schematic diagram of the interface through which the electronic device 100 outputs physiological parameter 1 can be found in the relevant descriptions of the embodiments shown in Figures 7C to 7F below, which will not be detailed here.
[0437] In some embodiments, the electronic device 100 may output one or more of the following while outputting the user's physiological parameter 1 (or after outputting physiological parameter 1): assessment result, value range, user status, historical curve, and reference suggestions. The assessment result characterizes whether the user's physiological parameter is normal. The value range refers to the normal range of the user's physiological parameter. The user status refers to the user's current state, such as fasting, non-fasting, exercise, high altitude, or sleep. The historical curve characterizes the relationship between the physiological parameter and time over a past period (e.g., 30 minutes, 3 hours, 24 hours). The reference suggestions can be used to guide the user to maintain or restore the physiological parameter to the normal range.
[0438] In other embodiments, after determining the user's physiological parameter 1, the electronic device 100 may also send an output instruction to other electronic devices. The output instruction may include the user's physiological parameter 1 and can be used to instruct the electronic device to output the user's physiological parameter 1. Optionally, the output instruction may also include, but is not limited to, any one or more of the following: user status, value range, evaluation result, historical curve, reference suggestions, etc. The electronic device 100 may output any one or more of the above content based on the output instruction.
[0439] The following sections describe how the evaluation results, value ranges, user status, historical curves, and reference suggestions were determined.
[0440] The following describes how user status is determined.
[0441] In some embodiments, the electronic device 100 can determine the user's state based on user information. The specific content of the user information can be found in the relevant description in step S501 above, and will not be repeated here. For example, the electronic device 100 can receive and respond to the user's operation of setting the user's state to determine the user's state. Another example is that the electronic device 100 can determine whether the user is in motion based on the user's motion information. Yet another example is that the electronic device 100 can determine whether the user is at a high altitude based on the user's location information, etc. It is understood that the embodiments described here are merely illustrative of how the electronic device 100 can determine the user's state based on user information. In this application embodiment, the electronic device 100 can also determine the user's state based on other information in the user information, and this application does not limit this.
[0442] The following describes how to determine the value range.
[0443] The value range can be the range of values for the physiological parameter stored in the electronic device 100. For example, Table 1 shows the value range of a physiological parameter stored in an electronic device 100 according to an embodiment of this application.
[0444] Table 1
[0445] As shown in Table 1, the electronic device 100 can store value ranges for one or more physiological parameters. For example, the value range for blood glucose can be [3.9, 6.1], the value range for blood ketones can be [0.05, 0.3], and the value range for uric acid can be [0.18, 0.42]. The unit for the above value ranges is millimoles per liter (mmol / L).
[0446] It is understood that the embodiments shown in Table 1 are only examples. In the embodiments of this application, the electronic device 100 may also store more, fewer or different ranges of physiological parameters than those shown in Table 1, and the ranges of physiological parameters may also be different from those described above. This application does not limit this.
[0447] In other embodiments, the electronic device 100 may also store the value ranges of physiological parameters under different user states. For example, Table 2 shows the value ranges of physiological parameters under different user states stored by another electronic device 100 provided in this application embodiment.
[0448] Table 2
[0449] As shown in Table 2, the electronic device 100 can store the value ranges of one or more physiological parameters under different user states. For example, in a fasting state, the blood glucose value range can be [3.9, 6.1]; in a non-fasting state, the blood glucose value range can be [3.9, 8.99]; in a fasting state, the blood ketone value range can be [0.05, 0.3]; in a non-fasting state, the blood ketone value range can be [0.05, 0.5]; in a fasting state, the uric acid value range can be [0.18, 0.42]; in a non-fasting state, the uric acid value range can be [0.18, 0.5]. The unit of the above value ranges is millimoles per liter (mmol / L).
[0450] It is understood that the embodiments shown in Table 2 are merely examples. In the embodiments of this application, the electronic device 100 may also store more, fewer, or different ranges of physiological parameters than those shown in Table 2, and the ranges of physiological parameters may also differ from those described above. This application does not impose any limitations on these ranges. Furthermore, the user status may also include more, fewer, or different user statuses than those described in the above embodiments. Moreover, in some embodiments, the electronic device 100 may also store the correspondence between factors such as user gender, age, and disease and the ranges of values. This application does not impose any limitations on these ranges.
[0451] Electronic device 100 can determine the value range based on one or more factors such as user status, user age, and gender.
[0452] The following describes how the evaluation results are determined.
[0453] In one possible implementation, the electronic device 100 can store the value ranges of the user's physiological parameters and determine the evaluation result based on the user's physiological parameter 1 and the corresponding value range of the physiological parameter. In another possible implementation, the electronic device 100 can also determine the value range of the user's current physiological parameters based on the correspondence between the user's gender, age, user status, or one or more factors and the value range, and determine the evaluation result based on the calibration value of the physiological parameters.
[0454] In some embodiments, the evaluation result may include normal and abnormal. When physiological parameter 1 falls within the range, the electronic device 100 can determine that the evaluation result is normal. When physiological parameter 1 does not fall within the range, the electronic device 100 can determine that the evaluation result is abnormal. Optionally, in the case of an abnormal evaluation result, the evaluation result may be further subdivided into any one or more of the following: too high, too low, too high, too low, etc., which are not limited herein.
[0455] In some embodiments, if the evaluation result is determined to be abnormal (or the evaluation result is determined to be abnormal, such as too high or too low), the electronic device 100 may output a warning. The warning output method may include, but is not limited to, any one or more of the following: display screen display, voice broadcast, vibration, indicator light flashing, etc.
[0456] The following describes how historical curves are determined.
[0457] In some embodiments, the electronic device 100 can determine the historical curve of a physiological parameter based on the calibration value of the physiological parameter measured in the current measurement. In other embodiments, the electronic device 100 can also determine the historical curve of the physiological parameter based on the calibration value of the physiological parameter measured in the current measurement and previously measured calibration values of the physiological parameter. The electronic device 100 can store the measurement time of each physiological parameter calibration value, and the electronic device 100 can determine the historical curve of the physiological parameter based on the different calibration values corresponding to different measurement times.
[0458] The following describes how to determine the reference recommendations.
[0459] In one possible implementation, the electronic device 100 can determine reference suggestions based on the assessment results. For example, if the assessment result is normal, the reference suggestions could be to advise the user to maintain their current lifestyle, or to advise the user to increase exercise and maintain a good sleep schedule, etc. If the assessment result is abnormal, the reference suggestions could be to advise the user to correct bad lifestyle habits, reduce the intake of greasy food, etc.
[0460] In another possible implementation, the electronic device 100 can also determine reference suggestions based on user information. For example, when the electronic device 100 determines that the user is in a high-altitude area based on user information, the reference suggestion may include "The oxygen is thin in the current area, so be careful to reduce strenuous exercise." As another example, when the electronic device 100 determines that the user has been in a fasting state for a duration exceeding a certain period (e.g., 4 hours), the reference suggestion may include "You are currently hungry, please eat as soon as possible," etc. It is understood that the embodiments described here are merely illustrative of how the electronic device 100 can determine reference suggestions based on user information. In this application embodiment, the electronic device 100 may also determine content different from the above reference suggestions based on user information, which is not limited herein.
[0461] S606. Electronic device 100 determines that monitoring condition 4 is met and sends information 4 to electronic device 200. Information 4 is used to request electronic device 200 to send an electrocardiogram signal to electronic device 100.
[0462] In some embodiments, monitoring condition 4 may include, but is not limited to, any one or more of the following: receiving an operation from the user to activate the ECG function, receiving a start command 2 from another electronic device, detecting abnormal physiological state of the user (e.g., blood glucose not falling within a preset blood glucose range), detecting abnormal psychological state of the user (e.g., being startled), detecting that the user is in motion, detecting that the user is insomnia, detecting abnormal body posture of the user (e.g., falling), detecting abnormal sports equipment of the user, detecting that the user's location is within a preset area (e.g., the user is in a high-altitude area), etc.
[0463] The determination method for each condition in monitoring condition 4 can also refer to the relevant content in step S601 above, and will not be repeated here.
[0464] In some other embodiments, monitoring condition 4 may be the same as monitoring condition 3, that is, when electronic device 100 determines that monitoring condition 3 is met, electronic device 100 may execute the above step S602 and the following step S608.
[0465] S607. Electronic device 200 acquires electrocardiogram (ECG) signals.
[0466] In some embodiments, the electronic device 200 may, in response to information 4, begin acquiring electrocardiogram (ECG) signals.
[0467] In other embodiments, the electronic device 200 may also periodically acquire electrocardiogram signals before receiving information 4.
[0468] The method by which electronic device 200 acquires electrocardiogram signals can be referred to the relevant content of step S503 shown in Figure 5A above, and will not be repeated here.
[0469] S608. Electronic device 200 sends an electrocardiogram signal to electronic device 100.
[0470] In some embodiments, electronic device 200 may send an electrocardiogram signal to electronic device 100 in response to information 4.
[0471] In some embodiments, electronic device 200 periodically sends electrocardiogram (ECG) signals to electronic device 100 before receiving information 4. In this case, step S608 described above may not be performed; furthermore, in this case, monitoring condition 4 may be used to trigger electronic device 100 to perform step S609 as described below.
[0472] S609. Electronic device 100 outputs electrocardiogram (ECG) signal.
[0473] The electronic device 100 can output electrocardiogram signals in one or more ways, such as display screen, audio broadcast, vibration, and indicator light flashing.
[0474] The electronic device 100 can also output electrocardiogram (ECG) signals. Optionally, after outputting the ECG (or simultaneously with outputting the ECG), the electronic device 100 can also output one or more of the following: one or more ECG indicators, the evaluation results of the ECG indicators, the evaluation results of ECG function, the value range of the ECG indicators, and the user's status. The value range of the ECG indicator refers to the normal range of the ECG indicator. The user status refers to the user's current state, such as resting state, exercise state, high altitude state, sleep state, etc. The evaluation results of the ECG indicator are used to indicate whether the ECG indicator belongs to the preset value range of the ECG indicator. The evaluation results of ECG function are used to indicate whether the user's heart function is normal.
[0475] The specific content and determination method of the ECG indicators can be referred to the relevant description in step S504 shown in Figure 5A above; the value range of the ECG indicators can be pre-stored by the electronic device 100; the evaluation result of the ECG indicators can be determined based on the ECG indicators and the value range of the ECG indicators, and the specific method can be referred to the relevant description in step S605 above; the evaluation result of the ECG function can be determined based on the evaluation result of one or more ECG indicators; the method of determining the user status can also refer to the relevant description in step S605 above, and will not be repeated here.
[0476] In some application scenarios, physiological parameter 1 can be blood glucose, and the output interface diagram of blood glucose can be referred to in Figures 7A-7F below.
[0477] For example, as shown in Figure 7A, the electronic device 100 displays a health application interface 700, which may include one or more items, such as blood glucose item 701, blood pressure item, electrocardiogram item 702, blood oxygen item, etc. Each item can be used to trigger the electronic device 100 to display the corresponding physiological parameter monitoring interface.
[0478] The electronic device 100 can receive and respond to the user's click operation on the blood glucose entry 701, and display the blood glucose monitoring interface 710 as shown in Figure 7B.
[0479] As shown in Figure 7B, the blood glucose monitoring interface 710 may include a measurement control 711 and a history control 712. The measurement control 711 can be used to trigger the electronic device 100 to determine and output the user's blood glucose, and the history control 712 is used to trigger the electronic device 100 to display past blood glucose measurement records (including measurement time and the user's blood glucose).
[0480] Electronic device 100 can receive and respond to the user's click operation on the measurement control 711. After determining the user's blood glucose based on the physiological data sent by electronic device 200, electronic device 100 can display the output interface 720 as shown in Figure 7C.
[0481] As shown in Figure 7C, the output interface 720 may include a blood glucose level 721, which indicates the user's blood glucose value. Optionally, the output interface 720 may also include, but is not limited to, any one or more of the following: an evaluation result 722, a value range 723, a user status 724, and a historical curve control 725. The evaluation result 722 can be used to indicate whether the user's blood glucose is normal. As shown in Figure 7C, the evaluation result 722 is a horizontal line, which can represent that the user's blood glucose value belongs to a preset value range, i.e., the user's blood glucose is normal. In some embodiments, if the user's blood glucose value is greater than the preset value range, the evaluation result can also be an upward arrow; if the user's blood glucose value is less than the preset value range, the evaluation result can also be a downward arrow. It is understood that the display method of the evaluation result 722 shown in Figure 7C is only an example. In the embodiments of this application, the evaluation result can also be represented by different symbols, text, etc., and this application does not limit this. The value range 723 is used to represent the reference range of the user's blood glucose, i.e., the normal value range of the user's blood glucose in the current user state. The user status 724 can be used to indicate the user's current state, for example, a fasting state. In some embodiments, the value range 723 may differ depending on the user's state. The historical curve control 725 can be used to trigger the electronic device 100 to display a historical blood glucose curve, which represents the relationship between the user's blood glucose value and time over a past period.
[0482] The electronic device 100 can receive and respond to a user's click operation on the historical curve control 725, and display the historical curve interface 730 as shown in Figure 7D. Alternatively, the electronic device 100 can also receive and respond to a user's swipe-up operation on the output interface 720, and display the historical curve and other content as shown in Figure 7D on the output interface 720.
[0483] As shown in Figure 7D, the historical curve interface 730 may include a historical curve 731, and optionally, may also include reference suggestions 732. The historical curve 731 can be used to characterize the relationship between a user's blood glucose levels and time over a past period. The reference suggestions 732 can be used to guide the user to maintain or restore blood glucose levels to a normal range. For example, the reference suggestions 732 may include the text "Stable blood glucose, please maintain." It is understood that the reference suggestions 732 shown in Figure 7D are only an example. In this embodiment, the reference suggestions 732 may also adopt a different output format than the above embodiments, and may include more, less, or different content than the above embodiments. This application does not limit this.
[0484] In other embodiments, the electronic device 100 may receive and respond to a user's click operation on the measurement control 711. After determining the user's blood glucose (i.e., blood glucose value) based on physiological data, if the user's blood glucose is abnormal, the electronic device 100 may optionally display a warning interface 740 as shown in FIG7E, or display an output interface 750 as shown in FIG7F.
[0485] As shown in Figure 7E, the warning interface 740 may include a warning 741, and optionally, a result viewing control 742. The warning 741 can be used to alert the user to an abnormal blood glucose level. For example, the warning 741 may include the text "Blood glucose too low, please eat as soon as possible!!". The result viewing control 742 can be used to trigger the electronic device 100 to display the blood glucose value.
[0486] The electronic device 100 can receive and respond to a user's click operation on the viewing results control 742, and display the output interface 750 as shown in FIG7F. In some embodiments, the electronic device 100 can also display the output interface 750 as shown in FIG7F when it detects that the display duration of the warning interface 740 is longer than a preset duration (e.g., 10 seconds, 15 seconds, etc.).
[0487] As shown in Figure 7F, the output interface 750 may include a blood glucose level 751, which can be the user's blood glucose value. Optionally, the output interface 750 may also include, but is not limited to, any one or more of the following: assessment result 752, value range 753, user status 754, and reference suggestion 755. The assessment result 752 can be used to indicate whether the user's blood glucose is normal. As shown in Figure 7F, the assessment result 752 is a downward arrow, which can indicate that the user's blood glucose value is less than a preset value range, i.e., the user's blood glucose is abnormal. The value range 753 is used to represent the user's blood glucose reference range, i.e., the range of blood glucose values when the user is in a healthy state. The user status 754 can be used to indicate the user's current status, for example, a fasting state. In some embodiments, the value range 753 may also be different depending on the user status. The output interface 750 may also include reference suggestion 755, for example, reference suggestion 755 may include the text "Blood glucose is too low, please eat as soon as possible!". It is understood that in some other embodiments, the output interface 750 may also display a historical blood glucose curve (or a historical curve control), which is used to characterize the relationship between the user's blood glucose value and time over a period of time. This application does not limit this.
[0488] It is understood that the embodiments shown in Figures 7A to 7F above are only two examples. In the embodiments of this application, the output physiological parameters may also be other physiological parameters (such as blood ketones, uric acid, etc.), the device for outputting physiological parameters may also be electronic device 200 or other electronic devices, and the content displayed in the output interface may include more, less or different content than the above embodiments. This application does not limit these contents here.
[0489] Figures 7G-7J show schematic diagrams of a set of electrocardiogram (ECG) signal output interfaces provided in embodiments of this application.
[0490] For example, as shown in Figure 7G, the electronic device 100 may display a health application interface 700, which may include one or more items, such as blood glucose item 701, blood pressure item, electrocardiogram item 702, blood oxygen item, etc. Each item can be used to trigger the electronic device 100 to display the corresponding physiological parameter monitoring interface.
[0491] The electronic device 100 can receive and respond to the user's click operation on the ECG entry 702 and display the ECG monitoring interface 760 as shown in Figure 7H.
[0492] As shown in Figure 7H, the ECG monitoring interface 760 may include a measurement control 761 and a history control 762. The measurement control 761 can be used to trigger the electronic device 100 to determine and output the user's ECG signal, and the history control 762 is used to trigger the electronic device 100 to display past ECG signal measurement records.
[0493] Electronic device 100 can receive and respond to the user's click operation on measurement control 761. After determining the user's electrocardiogram based on the electrocardiogram signal sent by electronic device 200, electronic device 100 can display the output interface 770 as shown in FIG7I.
[0494] As shown in Figure 7I, the output interface 770 may include an electrocardiogram 771, which may be a waveform diagram of an electrocardiogram signal.
[0495] In some embodiments, the electronic device 100 can also receive and respond to a user's swipe-up operation on the output interface 770. As shown in FIG7J, the electronic device 100 can display one or more of the following contents on the output interface 770: heart rate 772, heart rate assessment result 773, amplitude 774, amplitude assessment result 775, and user status 776, etc. Here, heart rate 772 is used to indicate the user's heart rate; heart rate assessment result 773 is used to indicate whether the user's heart rate is normal; amplitude 774 is used to indicate the amplitude of the electrocardiogram signal; amplitude assessment result 775 is used to indicate whether the amplitude of the electrocardiogram signal is normal; user status 776 is used to indicate the user's current status, such as resting state (or exercise state, etc.), and the user status may have a certain impact on the electrocardiogram signal. As shown in FIG7J, heart rate assessment result 773 and amplitude assessment result 775 are both horizontal lines, which can indicate that the user's electrocardiogram belongs to a preset value range, that is, the user's electrocardiogram is normal. Other specific details of heart rate assessment result 773 and amplitude assessment result 775 can be found in the relevant content of assessment result 722 in the embodiment shown in Figure 7C above, and will not be repeated here.
[0496] It is understood that the embodiments shown in Figures 7G-7J above are only examples. In the embodiments of this application, the output interface of the electrocardiogram signal may also include more, less or different content than the above embodiments, such as electrocardiogram indicators such as P wave duration and QT interval. This application does not limit this.
[0497] In some application scenarios, electronic device 100 can also prompt the user to perform electrocardiogram monitoring when it detects an abnormal value of physiological parameter 1.
[0498] For example, taking physiological parameter 1 as blood glucose, Figure 7K shows the prompt interface 780 of electronic device 100 when blood glucose is abnormal.
[0499] As shown in Figure 7K, the prompt interface 780 may include a prompt 781, an agreement control 782, and a rejection control 783. The prompt 781 can be used to prompt the user to perform ECG monitoring. The prompt 781 may include text, such as "Abnormal blood sugar detected; it is recommended to enable the ECG monitoring function." The agreement control 782 can be used to trigger electronic device 100 to send information 4 to electronic device 200, requesting electronic device 200 to send an ECG signal to electronic device 100. Optionally, the agreement control 782 may also display a countdown (e.g., 5 seconds, 3 seconds, etc.). When the countdown ends and electronic device 100 has not received the user's operation, electronic device 100 may send information 4 to electronic device 200. The rejection control 783 can be used to trigger electronic device 100 to stop displaying the prompt interface 780. Optionally, it may also trigger electronic device 100 to output blood sugar calibration values, etc.
[0500] Electronic device 100 can receive and respond to a user's click on the consent control 782, displaying an ECG monitoring interface 790 as shown in FIG7L. The ECG monitoring interface 790 is used to notify the user that electronic device 100 is acquiring ECG signals. In some embodiments, after receiving an ECG signal from electronic device 200, electronic device 100 can display an output interface 770 as shown in FIG7I above.
[0501] It is understood that Figures 7K-7L above are merely illustrative examples. When the value of physiological parameter 1 is abnormal, it can trigger a prompt to the user to turn on ECG monitoring. In this embodiment of the application, the electronic device 100 can also directly jump to the ECG monitoring interface when it detects that the value of physiological parameter 1 (such as blood glucose, blood ketones, etc.) is abnormal, and display the ECG signal after obtaining the ECG signal. This application does not limit this.
[0502] In other application scenarios, the electronic device 100 can have a micro-physical examination function. When the electronic device 100 detects that the user has enabled the micro-physical examination function, it can output one or more physiological parameters and electrocardiogram signals after determining a variety of physiological parameters and electrocardiogram signals.
[0503] For example, as shown in Figure 7M, the electronic device 100 can display a micro-health check interface 800. The micro-health check interface 800 may include a health check control 801, which can be used to trigger the electronic device 100 to output one or more physiological parameters and electrocardiogram (ECG) signals. Optionally, the micro-health check interface 800 may also display health check items, which can be used to prompt the user about the items that the micro-health check function can monitor. For example, in the embodiment shown in Figure 7M, the health check items may include ECG, blood glucose, and blood ketones. After the micro-health check function is enabled, the electronic device 100 can output ECG, blood glucose, and blood ketones, etc.
[0504] Optionally, before displaying the micro-health check interface 800, the electronic device 100 may also display an interface where the user can select health check items. The electronic device 100 can receive and respond to the user's operation of selecting health check items and display the micro-health check interface 800 as shown in Figure 7M.
[0505] The electronic device 100 can receive and respond to user clicks on the health check control 801. After determining the blood glucose, blood ketone, and electrocardiogram (ECG) signals, the electronic device 100 can display the output interface 810 as shown in Figure 7N. The output interface 810 may include an ECG 811, and may also include blood glucose values 812 and blood ketone values 813. Optionally, the output interface 810 may also include, but is not limited to, any one or more of the following: ECG indicators, blood glucose value range, blood ketone value range, blood glucose assessment results, and blood ketone assessment results.
[0506] It is understood that the embodiments shown in Figures 7M-7N are merely illustrative examples. The electronic device 100 can simultaneously output one or more physiological parameters and electrocardiogram signals. In the embodiments of this application, the items monitored by the micro-physical examination function may also be different from those in the above embodiments. The electronic device 100 may also simultaneously output multiple physiological parameters. This application does not limit this.
[0507] The functional modules of an electronic device 200 provided in the embodiments of this application are described below.
[0508] Figure 8 shows a schematic diagram of the functional modules of a measurement system 10 provided in an embodiment of this application.
[0509] As shown in Figure 8, the electronic device 200 may include an electrochemical module 2001, an electrocardiogram module 2002, a data processing module 2003, a communication module 2004, etc., and optionally may also include any one or more of the following: a temperature module 2005, a control module 2006, an output module 2007, etc. Wherein:
[0510] The electrochemical module 2001 can acquire current data for one or more physiological parameters (e.g., blood glucose, blood ketones, blood lactate, uric acid, etc.). In some embodiments, the electrochemical module 2001 can receive and respond to message N1 sent by the control module 2006 or the communication module 2004, and begin acquiring current data for one or more physiological parameters specified by message N1. The electrochemical module 2001 can send the current data to the data processing module 2003.
[0511] The ECG module 2002 can acquire ECG signals and send them to the data processing module 2003. In some embodiments, the ECG signal can also be acquired in response to message N2 sent by the control module 2006 or the communication module 2004.
[0512] The data processing module 2003 can determine one or more physiological parameters based on the current data sent by the electrochemical module 2001. In some embodiments, the data processing module 2003 can also determine electrocardiogram (ECG) indicators and / or electrocardiogram (ECG) based on the ECG signal sent by the ECG module 2002. In some embodiments, the data processing module 2003 can also calibrate the values of physiological parameters based on the body temperature sent by the temperature module 2005. The data processing module 2003 can send one or more of the physiological parameters, ECG indicators, ECG, etc., to the output module 2007 or the communication module 2004.
[0513] The communication module 2004 can receive data (e.g., one or more physiological parameters, electrocardiogram indicators, electrocardiograms, etc.) sent by the data processing module 2003, and send the received data to the electronic device 100. In some embodiments, the communication module 2004 can receive and respond to information 1 sent by other electronic devices (e.g., electronic device 100), and send the message N1 to the electrochemical module 2001, whereby message N1 instructs the electrochemical module 2001 to begin acquiring current data of one or more physiological parameters specified by message N1. The communication module 2004 can also receive and respond to information 2 sent by other electronic devices (e.g., electronic device 100), and send the message N2 to the electrocardiogram module 2002, whereby message N2 instructs the electrocardiogram module 2002 to begin acquiring electrocardiogram signals. In other embodiments, the communication module 2004 can also receive information 1 sent by other electronic devices (e.g., electronic device 100) and send information 1 to the control module 2006. The communication module 2004 can also receive information 2 sent by other electronic devices (e.g., electronic device 100) and send information 2 to the control module 2006.
[0514] The control module 2006 can also determine whether monitoring condition 1 or monitoring condition 2 is met. When monitoring condition 1 is met, the control module 2006 can send message N1 to the electrochemical module 2001, which instructs the electrochemical module 2001 to begin acquiring current data of one or more physiological parameters specified in message N1. When monitoring condition 2 is met, the control module 2006 can send message N2 to the electrochemical module 2001, which instructs the electrocardiogram module 2002 to begin acquiring electrocardiogram signals. In some embodiments, monitoring condition 1 may include receiving information 1 sent by the communication module 2004, and monitoring condition 2 may include receiving information 2 sent by the communication module 2004.
[0515] Temperature module 2005 can measure the body temperature of a user or organism and send the body temperature to data processing module 2003.
[0516] The output module 2007 can receive data sent by the data processing module 2003 (such as one or more physiological parameters, electrocardiogram indicators, electrocardiograms, etc.) and output the received data using one or more methods such as voice broadcast, display screen, vibration, and indicator light flashing.
[0517] It is understood that the embodiment shown in Figure 8 is only an example. In the embodiments of this application, the electronic device 200 may also include more, fewer or different functional modules than the above embodiments, or combine the above multiple functional modules into one functional module, or split any of the above functional modules into multiple functional modules. This application does not limit this.
[0518] The functional modules of a measurement system 10 provided in the embodiments of this application are described below.
[0519] Figure 9 shows a schematic diagram of the functional modules of a measurement system 10 provided in an embodiment of this application.
[0520] As shown in Figure 9, the measurement system 10 may include electronic device 100 and electronic device 200. Electronic device 100 may include a communication module 1002, a data processing module 1003, an output module 1006, etc. Optionally, electronic device 100 may also include, but is not limited to, any one or more of the following: an interaction module 1001, a user information module 1004, and an evaluation module 1005. Electronic device 200 may include an electrochemical module 2001, an electrocardiogram module 2002, and a communication module 2004. Optionally, electronic device 200 may also include any one or more of the following: a temperature module 2005, a control module 2006, etc. Wherein:
[0521] The interaction module 1001 can receive and respond to user operations, such as activating the physiological monitoring function or activating the electrocardiogram (ECG) function. In response to the user's activation of the physiological monitoring function, the interaction module 1001 can send message N3 to the communication module 1002. Message N3 can instruct the communication module 1002 to send information 3 to the electronic device 200, whereby information 3 requests physiological data for one or more specified physiological parameters.
[0522] The communication module 1002 can communicate with other electronic devices (such as electronic device 200). In some embodiments, the communication module 1002 can receive and respond to message N3, sending information 3 to the communication module 2004 in electronic device 200, whereby information 3 requests physiological data. The communication module 1002 can also receive physiological data sent by the communication module 2004 in electronic device 200 and send the physiological data to the data processing module 1003. In some embodiments, the communication module 1002 can also receive physiological parameters (i.e., values of physiological parameters) sent by the data processing module 1003, and receive evaluation results and / or reference suggestions sent by the evaluation module 1005, and send one or more of the physiological parameters, evaluation results, and reference suggestions to other electronic devices.
[0523] The data processing module 1003 can determine physiological parameters, such as blood glucose and blood ketones, based on the physiological data sent by the communication module 1002. After determining the physiological parameters, the data processing module 1003 can send the physiological parameters to the output module 1006 or the communication module 1002. In some embodiments, the data processing module 1003 can also send the physiological parameters to the evaluation module 1005.
[0524] User information module 1004 can acquire user information. In some embodiments, user information module 1004 can collect user information; in other embodiments, user information module 1004 can receive user information acquired by communication module 1002 from other electronic devices. In some embodiments, user information module 1004 can determine the user status based on the user information and send the user status to evaluation module 1005. In some embodiments, user information module 1004 can also determine whether the user information meets monitoring conditions (e.g., monitoring condition 3, monitoring condition 4, etc.). If monitoring condition 3 is met, user information module 1004 can send message N4 to communication module 1002, which can be used to instruct communication module 1002 to send information 3 to electronic device 200. If monitoring condition 4 is met, user information module 1004 can send message N5 to communication module 1002, which can be used to instruct communication module 1002 to send information 4 to electronic device 200.
[0525] The evaluation module 1005 can store the value ranges of physiological parameters. Based on the value ranges and the physiological parameters themselves, the evaluation module 1005 can determine an evaluation result indicating whether the physiological parameter is normal. In some embodiments, the evaluation module 1005 can also receive the user status sent by the user information module 1004 and determine the evaluation result based on the relationship between the user status and the value ranges of the physiological parameters, as well as the physiological parameters themselves. In other embodiments, the evaluation module 1005 can also determine reference suggestions based on the user status and / or the evaluation results, guiding the user to maintain (or restore) the physiological parameter to its normal range. The evaluation module 1005 can send the evaluation results and / or reference suggestions to the output module 1006, or to other electronic devices via the communication module 1002.
[0526] The output module 1006 can receive and output physiological parameters sent by the data processing module 1003, and can also receive and output evaluation results and / or reference suggestions sent by the evaluation module 1005, etc.
[0527] In electronic device 200, communication module 2004 can communicate with electronic device 100. In some embodiments, communication module 2004 can receive information 3 sent by communication module 1002, send information 3 to control module 2006, or send message N6 to electrochemical module 2001. Message N6 is used to instruct electrochemical module 2001 to send current data of one or more specified physiological parameters to communication module 2004. In some embodiments, communication module 2004 can receive information 4 sent by communication module 1002, send information 4 to control module 2006, or send message N7 to electrocardiogram module 2002. Message N7 is used to instruct electrocardiogram module 2002 to send electrocardiogram signals to communication module 2004.
[0528] The electrochemical module 2001 can acquire current data of one or more physiological parameters (e.g., blood glucose, blood ketones, blood lactate, uric acid, etc.). In some embodiments, the electrochemical module 2001 can receive and respond to message N6 sent by the control module 2006 or the communication module 2004, and begin acquiring current data of one or more physiological parameters specified by message N6. In other embodiments, the electrochemical module 2001 can respond to message N6 sent by the control module 2006 or the communication module 2004, and send current data of one or more physiological parameters to the communication module 2004.
[0529] The ECG module 2002 can acquire ECG signals. In some embodiments, the ECG signal can also be received and, in response to message N7 sent by the control module 2006 or the communication module 2004, begin acquiring the ECG signal. In other embodiments, the ECG module 2002 can, in response to message N7 sent by the control module 2006 or the communication module 2004, send the ECG signal to the communication module 2004.
[0530] The control module 2006 can also determine whether monitoring condition 1 or monitoring condition 2 is met. When monitoring condition 1 is met, the control module 2006 can send message N1 to the electrochemical module 2001, which instructs the electrochemical module 2001 to begin acquiring current data of one or more physiological parameters specified in message N1. When monitoring condition 2 is met, the control module 2006 can send message N2 to the electrochemical module 2001, which instructs the electrocardiogram module 2002 to begin acquiring electrocardiogram signals. In some embodiments, monitoring condition 1 may include receiving information 3 sent by the communication module 2004, and monitoring condition 2 may include receiving information 4 sent by the communication module 2004.
[0531] Temperature module 2005 can measure the body temperature of a user or organism and send the body temperature to communication module 2004.
[0532] In other embodiments, the electronic device 200 may also include, but is not limited to, any one or more of the following: a data processing module, an evaluation module, an output module, etc. The functional descriptions of these one or more modules can be referred to the functional descriptions of the relevant modules in the embodiments shown in Figures 8 or 9 above, and will not be repeated here. It should be noted that if the electronic device 200 includes a data processing module, the physiological data sent by the communication module 2004 to the electronic device 100 may also refer to the values of physiological parameters (e.g., measured values or calibrated values of physiological parameters).
[0533] It is understood that the embodiment shown in Figure 9 is only an example. In the embodiments of this application, the measurement system 10 may include more, fewer or different functional modules than the above embodiments, or combine the above multiple functional modules into one functional module, or split any of the above functional modules into multiple functional modules. This application does not limit this.
[0534] It should be noted that the measurement method provided in this application embodiment can not only measure the physiological parameters and electrocardiogram signals of users, but also measure the physiological parameters and electrocardiogram signals of other organisms (such as pets, poultry, livestock, endangered animals, etc.), and this application does not limit it here.
[0535] For ease of subsequent description, the aforementioned electronic devices 100 and 200 can be collectively referred to as a device. It should be understood that the division of units within this device is merely a logical functional division; in actual implementation, they can be fully or partially integrated into a single physical entity, or they can be physically separated. Furthermore, the units within the device can be implemented by a processor calling software; for example, the device includes a processor connected to a memory containing instructions. The processor calls the instructions stored in the memory to implement any of the above methods or to realize the functions of each unit within the device. The processor can be, for example, a general-purpose processor, such as a central processing unit (CPU) or a microprocessor, and the memory can be internal or external to the device. Alternatively, the units in the device can be implemented as hardware circuits. The functionality of some or all units can be achieved through the design of these hardware circuits, which can be understood as one or more processors. For example, in one implementation, the hardware circuit is an application-specific integrated circuit (ASIC). The functionality of some or all of the above units is achieved through the design of the logical relationships between the components within the circuit. In another implementation, the hardware circuit can be implemented using a programmable logic device (PLD). Taking a field-programmable gate array (FPGA) as an example, it can include a large number of logic gates. The connection relationships between the logic gates are configured through a configuration file, thereby achieving the functionality of some or all of the above units. All units of the above device can be implemented entirely through processor-invoked software, entirely through hardware circuits, or partially through processor-invoked software with the remaining parts implemented through hardware circuits.
[0536] In this application embodiment, a processor is a circuit with data processing capabilities. In one implementation, the processor can be a circuit with instruction reading and execution capabilities, such as a CPU, microprocessor, graphics processing unit (GPU) (which can be understood as a type of microprocessor), or digital signal processor (DSP). In another implementation, the processor can implement certain functions through the logical relationships of hardware circuits. These logical relationships of hardware circuits are fixed or reconfigurable. For example, the processor is a hardware circuit implemented as an ASIC or PLD, such as an FPGA. In a reconfigurable hardware circuit, the process of the processor loading a configuration document and configuring the hardware circuit can be understood as the process of the processor loading instructions to implement the functions of some or all of the above units. Furthermore, it can also be a hardware circuit designed for artificial intelligence, which can be understood as an ASIC, such as a Neural Network Processing Unit (NPU), Tensor Processing Unit (TPU), or Deep Learning Processing Unit (DPU).
[0537] As can be seen, each unit in the above device can be one or more processors (or processing circuits) configured to implement the above methods, such as: CPU, GPU, NPU, TPU, DPU, microprocessor, DSP, ASIC, FPGA, or a combination of at least two of these processor forms.
[0538] Furthermore, the units in the above devices can be integrated in whole or in part, or they can be implemented independently. In one implementation, these units are integrated together as a system-on-a-chip (SOC). The SOC may include at least one processor for implementing any of the above methods or implementing the functions of the units in the device. The at least one processor may be of different types, such as CPU and FPGA, CPU and artificial intelligence processor, CPU and GPU, etc.
[0539] The following describes a possible physical structure of the electronic device 300 provided in the embodiments of this application.
[0540] For example, Figure 10 shows a schematic diagram of the physical structure of an electronic device 300 provided in an embodiment of this application.
[0541] As shown in Figure 10, the electronic device 300 can be any one of the electronic devices 100 and 200 in the above embodiments. The electronic device 300 may include a processor 1101 and a memory 1102, and optionally, it may also include a transmitter 1103 and a receiver 1104. The processor 1101, memory 1102, transmitter 1103, and receiver 1104 can be interconnected or interconnected via a bus 1105.
[0542] For example, memory 1102 is used to store computer programs and data of electronic device 300. Memory 1102 may include, but is not limited to, random access memory (RAM), read-only memory (ROM), erasable programmable read-only memory (EPROM), or compact disc read-only memory (CD-ROM).
[0543] The software or program code required for all or part of the functions of the electronic device 300 in the above method embodiments is stored in the memory 1102.
[0544] In one possible implementation, if the software or program code required for some functions is stored in the memory 1102, then in addition to calling the program code in the memory 1102 to implement some functions, the processor 1101 can also cooperate with other components (such as the transmitter 1103 and the receiver 1104) to jointly complete other functions described in the method embodiment (such as the function of receiving or sending data).
[0545] Transmitter 1103 and receiver 1104 are used to support electronic device 300 in communication, such as receiving or sending data or signals.
[0546] For example, processor 1101 may be a CPU, GPU, NPU, TPU, DPU, microprocessor, DSP, ASIC, FPGA, or a combination of at least two of these processor types, as described above. Processor 1101 may be used to read programs stored in memory 1102 and execute operations performed by electronic device 300 in any of the above embodiments.
[0547] The specific operation and beneficial effects of each unit in the electronic device 300 shown in Figure 10 can be found in the corresponding descriptions in the above method embodiments, and will not be repeated here.
[0548] It is understood that the embodiment shown in FIG10 is only an example. In the embodiments of this application, the electronic device 300 may also include more, fewer, or different devices than those shown in FIG10. This application does not limit the scope of the invention.
[0549] The following describes a chip system provided by an embodiment of this application.
[0550] This application also provides a chip system including at least one processor for implementing the functions involved in any side of the electronic device 100 or electronic device 200 in any of the above embodiments.
[0551] In one possible design, the chip system also includes a memory for storing program instructions and data, which may be located within or outside the processor.
[0552] The chip system can consist of chips or include chips and other discrete components.
[0553] Optionally, the chip system may contain one or more processors. These processors can be implemented in hardware or software. When implemented in hardware, the processor can be a logic circuit, an integrated circuit, etc. When implemented in software, the processor can be a general-purpose processor, implemented by reading software code stored in memory.
[0554] Optionally, the chip system may contain one or more memories. The memory may be integrated with the processor or disposed separately from it; this application embodiment does not limit this. For example, the memory may be a non-transient processor, such as a read-only memory (ROM), which may be integrated with the processor on the same chip or disposed separately on different chips. This application embodiment does not specifically limit the type of memory or the arrangement of the memory and processor.
[0555] For example, the chip system may be a field programmable gate array (FPGA), an application specific integrated circuit (ASIC), a system on chip (SoC), a central processor unit (CPU), a network processor (NP), a digital signal processor (DSP), a micro controller unit (MCU), a programmable logic device (PLD), or other integrated chips.
[0556] It is understood that the above chip system is only an example. In the embodiments of this application, the chip system may also include more, fewer, or different devices than those in the above embodiments. This application does not limit the scope of the invention.
[0557] Figure 11 shows a flowchart of a measurement method provided in an embodiment of this application.
[0558] As shown in Figure 11, the specific procedure of the measurement method may include the following steps:
[0559] S1101. When the first electrode group and the second electrode group are implanted in subcutaneous tissue, the first electronic device determines the first physiological parameter through the first electrode group; the first electronic device includes the first electrode group and the second electrode group, and the distance between the first electrode group and the second electrode group is greater than the first distance.
[0560] The first electronic device may be the electronic device 200 in the above embodiments. The first electrode group may be the electrode group 1 in the above embodiments, and the second electrode group may be the electrode group 2 in the above embodiments.
[0561] The first distance can be a preset distance, such as three centimeters. When the distance between the first electrode group and the second electrode group is greater than the first distance, the first electrode group and the second electrode group can measure electrocardiogram signals.
[0562] In one possible implementation, the first physiological parameter may include, but is not limited to, any one or more of the following: blood glucose, blood ketones, uric acid, blood lactate, etc.
[0563] The specific method by which the first electronic device determines the first physiological parameter through the first electrode group can be referred to the relevant description in the embodiment shown in Figure 5A above, and will not be repeated here.
[0564] In one possible implementation, the first electrode group includes a first working electrode and a first pair of electrodes, and the second electrode group includes a second working electrode; the first pair of electrodes forms a circuit with the first working electrode; determining a first physiological parameter through the first electrode group specifically includes: determining the first physiological parameter through the first working electrode and the first pair of electrodes; determining an electrocardiogram (ECG) signal through the first electrode group and the second electrode group specifically includes: determining the ECG signal through the first working electrode and the second working electrode, or, determining the ECG signal through the first pair of electrodes and the second working electrode.
[0565] In this way, the first electrode group can form a two-electrode system through which the first physiological parameter can be measured. The first working electrode (or the first pair of electrodes) in the first electrode group and any one electrode in the second electrode group can be used as the LA electrode and RA electrode, respectively, to measure the electrocardiogram signal.
[0566] In one possible implementation, the first electrode group includes a first working electrode and a first pair of electrodes, and the second electrode group includes a second working electrode; the first pair of electrodes forms a circuit with the first working electrode; the first working electrode or the first pair of electrodes is connected to the right leg drive circuit; determining a first physiological parameter through the first electrode group specifically includes: determining the first physiological parameter through the first working electrode and the first pair of electrodes; determining an electrocardiogram signal through the first electrode group and the second electrode group specifically includes: determining the electrocardiogram signal through the first working electrode, the first pair of electrodes, and the second working electrode.
[0567] The electrode connected to the right leg drive circuit can serve as the right leg drive RLD electrode. The right leg drive circuit can be used to cancel common-mode signals. The specific circuit composition of the right leg drive circuit can be found in the relevant content of the embodiments shown in Figure 4C above, and will not be repeated here.
[0568] In this way, the first electrode group can form a two-electrode system through which the first physiological parameter can be measured. The first working electrode, the first pair of electrodes in the first electrode group, and any one of the electrodes in the second electrode group can be used as the LA electrode, RLD electrode, and RA electrode, respectively, to measure the electrocardiogram signal.
[0569] In one possible implementation, the first electrode group includes a first working electrode, a first reference electrode, and a first pair of electrodes; the first reference electrode is used to control the voltage of the first working electrode, and the first pair of electrodes forms a circuit with the first working electrode; determining a first physiological parameter through the first electrode group specifically includes: generating a first current through the first working electrode; and determining the first physiological parameter based on the first current.
[0570] In this way, the first electrode group can form a three-electrode system, through which the first current is generated and conducted.
[0571] In one possible implementation, the second electrode assembly includes a second working electrode, a second reference electrode, and a second pair of electrodes; the second reference electrode is used to control the voltage of the second working electrode, and the second pair of electrodes is used to form a circuit with the second working electrode; the method further includes: generating a second current through the second working electrode; and determining a second physiological parameter based on the second current.
[0572] In this way, the second electrode group can form a three-electrode system, through which a second current is generated and conducted.
[0573] For example, taking the embodiments shown in Figures 4C-4J above as an example, in the above embodiments, the first working electrode can be working electrode W1, the second working electrode can be working electrode W2, the first pair of electrodes can be counter electrode C1, the second pair of electrodes can be counter electrode C2, the first reference electrode can be reference electrode R1, and the second reference electrode can be reference electrode R2.
[0574] S1102. The first electronic device determines the electrocardiogram signal through the first electrode group and the second electrode group.
[0575] In one possible implementation, the electrocardiogram (ECG) signal is determined by a first electrode group and a second electrode group, specifically by determining the ECG signal by any one electrode in the first electrode group and any one electrode in the second electrode group.
[0576] The left and right arm electrodes can be selected from one electrode in the first electrode group and one electrode in the second electrode group, respectively. In this way, electrocardiogram signals can be measured using the left and right arm electrodes.
[0577] In one possible implementation, the electrocardiogram (ECG) signal is determined by a first electrode group and a second electrode group, specifically including: determining the ECG signal by any two electrodes in the first electrode group and any one electrode in the second electrode group; or, determining the ECG signal by any two electrodes in the first electrode group and any two electrodes in the second electrode group.
[0578] The left arm electrode and right arm electrode can be selected from one electrode in the first electrode group and one electrode in the second electrode group, respectively. The right leg drive electrode can be an electrode from either the first electrode group or the second electrode group. In this way, electrocardiogram (ECG) signals can be measured using the left arm electrode, right arm electrode, and right leg drive electrode. The right leg drive electrode is used to cancel common-mode signals through the right leg drive circuit.
[0579] In this way, the electrochemical electrodes in the first electrode group can be used to measure both the first physiological parameter and the electrocardiogram signal.
[0580] In one possible implementation, the electrocardiogram (ECG) signal is determined by any two electrodes in the first electrode group and any one electrode in the second electrode group. Specifically, when the first pair of electrodes is connected to the right leg drive circuit, the ECG signal is determined by the first pair of electrodes, the first working electrode, and the second reference electrode.
[0581] In one possible implementation, the electrocardiogram (ECG) signal is determined by any one electrode in the first electrode group and any two electrodes in the second electrode group. Specifically, when the second pair of electrodes is connected to the right leg drive circuit, the ECG signal is determined by the second pair of electrodes, the second working electrode, and the first reference electrode.
[0582] It should be noted that the above two implementation methods are just two examples. In this application, other electrodes in the first electrode group and the second electrode group can also be selected to measure electrocardiogram signals. This application does not limit this.
[0583] In one possible implementation, the first electrode group further includes a first ECG electrode and a second ECG electrode, and the second electrode group further includes a third ECG electrode. The second ECG electrode is connected to a right leg drive circuit. The ECG signal is determined by the first electrode group and the second electrode group, specifically by determining the ECG signal through the first ECG electrode, the second ECG electrode, and the third ECG electrode.
[0584] In this way, electrocardiogram (ECG) signals can be measured using individually set ECG electrodes.
[0585] Using the measurement method provided in this application, users' electrocardiogram signals can be measured anytime and anywhere, as well as physiological parameters such as blood glucose, blood ketones, blood lactic acid, and uric acid.
[0586] In one possible implementation, the first electronic device further includes a first microneedle sensor and a second microneedle sensor, the first microneedle sensor including a first electrode group and the second microneedle sensor including a second electrode group.
[0587] For example, the first microneedle sensor may be the microneedle sensor 303 shown in Figures 3A-3B above, and the second microneedle sensor may be the microneedle sensor 304 shown in Figures 3A-3B above.
[0588] In some embodiments, a microneedle sensor may refer to a sensor with a shape similar to a microneedle, and the microneedle sensor may have multiple electrodes disposed inside. Thus, a first electrode group and a second electrode group can be disposed in the microneedle sensor.
[0589] In one possible implementation, the first electronic device further includes a first array sensor and a second array sensor, the first array sensor including a first electrode group and the second array sensor including a second electrode group.
[0590] In some embodiments, an array sensor may refer to a sensor that includes multiple electrodes arranged in an array.
[0591] For example, the first array sensor may be the array sensor 307 shown in Figures 3D-3E above, and the second array sensor may be the array sensor 308 shown in Figures 3D-3E above.
[0592] In this way, the first electrode group and the second electrode group can be arranged in the array sensor in the form of arrays.
[0593] In one possible implementation, the first electronic device further includes a first microneedle sensor and a second array sensor, the first microneedle sensor including a first electrode group and the second array sensor including a second electrode group.
[0594] In this way, the first electrode group can be set in the microneedle sensor, and the second electrode group can be set in the array sensor in the form of an array.
[0595] In one possible implementation, before determining the first physiological parameter via the first electrode group, the method further includes: determining that a first condition is met, the first condition including any one or more of the following: receiving first information sent by a second electronic device, the first information being used to instruct the first electronic device to determine the first physiological parameter; detecting that the first electrode group and the second electrode group are implanted in subcutaneous tissue; detecting an abnormal electrocardiogram signal.
[0596] Thus, the first condition can be the trigger condition for measuring the first physiological parameter.
[0597] The first condition can be monitoring condition 1 in the embodiment shown in Figure 5A above.
[0598] In one possible implementation, before determining the electrocardiogram (ECG) signal via the first electrode group and the second electrode group, the method further includes: determining that a second condition is met, the second condition including any one or more of the following: receiving second information sent by a second electronic device, the second information being used to instruct the first electronic device to determine the ECG signal; detecting that the first electrode group and the second electrode group are implanted in subcutaneous tissue; detecting that a first physiological parameter does not belong to a first interval.
[0599] Thus, the second condition can be the triggering condition for determining the electrocardiogram signal.
[0600] The second condition can be monitoring condition 2 in the embodiment shown in Figure 5A above.
[0601] In one possible implementation, after determining the first physiological parameter through the first electrode group, the method further includes: outputting the first physiological parameter, or sending the first physiological parameter to a second electronic device.
[0602] In this way, the first physiological parameter can be output, or the first physiological parameter can be output through other electronic devices.
[0603] In one possible implementation, after determining the electrocardiogram (ECG) signal via the first and second electrode groups, the method further includes: outputting the ECG signal, or sending the ECG signal to a second electronic device.
[0604] In this way, ECG signals can be output, or ECG signals can be output through other electronic devices.
[0605] The second electronic device may be the electronic device 100 in the above embodiments.
[0606] The specific method for outputting the first physiological parameter and electrocardiogram signal can be referred to the relevant content in the embodiments shown in Figures 5A and 7A-7N above, and will not be repeated here.
[0607] The various embodiments of this application can be combined arbitrarily to achieve different technical effects.
[0608] In the above embodiments, implementation can be achieved, in whole or in part, through software, hardware, firmware, or any combination thereof. When implemented in software, it can be implemented, in whole or in part, as a computer program product. The computer program product includes one or more computer instructions. When the computer program instructions are loaded and executed on a computer, all or part of the processes or functions described in this application are generated. The computer can be a general-purpose computer, a special-purpose computer, a computer network, or other programmable device. The computer instructions can be stored in a computer-readable storage medium or transmitted from one computer-readable storage medium to another. For example, the computer instructions can be transmitted from one website, computer, server, or data center to another website, computer, server, or data center via wired (e.g., coaxial cable, fiber optic, digital subscriber line) or wireless (e.g., infrared, wireless, microwave, etc.) means. The computer-readable storage medium can be any available medium accessible to a computer or a data storage device such as a server or data center that integrates one or more available media. The available medium can be a magnetic medium (e.g., floppy disk, hard disk, magnetic tape), an optical medium (e.g., DVD), or a semiconductor medium (e.g., solid-state disk (SSD)).
[0609] Those skilled in the art will understand that all or part of the processes in the methods of the above embodiments can be implemented by a computer program instructing related hardware. This program can be stored in a computer-readable storage medium, and when executed, it can include the processes described in the above method embodiments. The aforementioned storage medium includes various media capable of storing program code, such as ROM or random access memory (RAM), magnetic disks, or optical disks.
[0610] In summary, the above description is merely an embodiment of the technical solution of the present invention and is not intended to limit the scope of protection of the present invention. Any modifications, equivalent substitutions, improvements, etc., made according to the disclosure of the present invention should be included within the scope of protection of the present invention.
Claims
1. A measurement method, characterized in that, The invention is applied to a first electronic device, which includes a first electrode group and a second electrode group, wherein the distance between the first electrode group and the second electrode group is greater than a first distance. When the first electrode group and the second electrode group are implanted in subcutaneous tissue, the method includes: The first physiological parameter is determined by the first electrode group; Electrocardiogram (ECG) signals are determined using the first electrode group and the second electrode group.
2. The method according to claim 1, characterized in that, The first electrode group includes a first working electrode and a first pair of electrodes, and the second electrode group includes a second working electrode; the first pair of electrodes and the first working electrode form a circuit; the first working electrode or the first pair of electrodes is connected to the right leg drive circuit. The determination of the first physiological parameter through the first electrode set specifically includes: The first physiological parameter is determined by the first working electrode and the first pair of electrodes; The determination of electrocardiogram signals through the first electrode group and the second electrode group specifically includes: The electrocardiogram signal is determined by the first working electrode, the first pair of electrodes, and the second working electrode.
3. The method according to claim 1, characterized in that, The first electrode group includes a first working electrode, a first reference electrode, and a first pair of electrodes; the first reference electrode is used to control the voltage of the first working electrode, and the first pair of electrodes forms a circuit with the first working electrode. The determination of the first physiological parameter through the first electrode set specifically includes: A first current is generated through the first working electrode; The first physiological parameter is determined based on the first current.
4. The method according to claim 3, characterized in that, The second electrode group includes a second working electrode, a second reference electrode, and a second pair of electrodes; The second reference electrode is used to control the voltage of the second working electrode, and the second pair of electrodes is used to form a circuit with the second working electrode; the method further includes: A second current is generated through the second working electrode; The second physiological parameter is determined based on the second current.
5. The method according to claim 4, characterized in that, The determination of electrocardiogram signals through the first electrode group and the second electrode group specifically includes: The electrocardiogram signal is determined by any two electrodes in the first electrode group and any one electrode in the second electrode group; or, The electrocardiogram signal is determined by any one electrode from the first electrode group and any two electrodes from the second electrode group.
6. The method according to claim 5, characterized in that, The electrocardiogram (ECG) signal is determined using any two electrodes from the first electrode group and any one electrode from the second electrode group, specifically including: When the first pair of electrodes is connected to the right leg drive circuit, the electrocardiogram signal is determined by the first pair of electrodes, the first working electrode, and the second reference electrode.
7. The method according to claim 3 or 4, characterized in that, The first electrode group further includes a first ECG electrode and a second ECG electrode, and the second electrode group further includes a third ECG electrode. The second ECG electrode is connected to a right leg drive circuit. The determination of electrocardiogram signals through the first electrode group and the second electrode group specifically includes: The electrocardiogram (ECG) signal is determined using the first ECG electrode, the second ECG electrode, and the third ECG electrode.
8. The method according to any one of claims 1-7, characterized in that, The first electronic device further includes a first microneedle sensor and a second microneedle sensor, wherein the first microneedle sensor includes the first electrode group and the second microneedle sensor includes the second electrode group.
9. The method according to any one of claims 1-7, characterized in that, The first electronic device further includes a first array sensor and a second array sensor, wherein the first array sensor includes the first electrode group and the second array sensor includes the second electrode group.
10. The method according to any one of claims 1-9, characterized in that, Before determining the first physiological parameter using the first electrode set, the method further includes: The condition is determined to be met, which includes one or more of the following: receiving first information sent by a second electronic device, the first information being used to instruct the first electronic device to determine a first physiological parameter; detecting that the first electrode group and the second electrode group are implanted in subcutaneous tissue; and detecting an abnormal electrocardiogram signal.
11. The method according to any one of claims 1-10, characterized in that, Before determining the electrocardiogram signal through the first electrode group and the second electrode group, the method further includes: The second condition is determined to be met, which includes one or more of the following: receiving second information sent by a second electronic device, the second information being used to instruct a first electronic device to determine an electrocardiogram signal; detecting that the first electrode group and the second electrode group are implanted in subcutaneous tissue; detecting that a first physiological parameter does not belong to a first interval.
12. The method according to any one of claims 1-11, characterized in that, After determining the first physiological parameter using the first electrode set, the method further includes: Output the first physiological parameter, or send the first physiological parameter to the second electronic device.
13. The method according to any one of claims 1-12, characterized in that, After determining the electrocardiogram signal using the first electrode group and the second electrode group, the method further includes: Output the electrocardiogram (ECG) signal, or send the ECG signal to a second electronic device.
14. The method according to any one of claims 1-13, characterized in that, The first physiological parameter includes one or more of the following: blood glucose, blood ketones, uric acid, and blood lactate.
15. An electronic device, specifically a first electronic device, characterized in that: It includes a first electrode group and a second electrode group, wherein the distance between the first electrode group and the second electrode group is greater than a first distance; The first electrode assembly is used to determine a first physiological parameter when the first electrode assembly is implanted in subcutaneous tissue; The second electrode assembly is used to determine a second physiological parameter when the second electrode assembly is implanted in subcutaneous tissue; The first electrode group and the second electrode group are also used to determine electrocardiogram signals when the first electrode group and the second electrode group are implanted in subcutaneous tissue.
16. The electronic device according to claim 15, characterized in that, The first electrode group includes a first working electrode and a first pair of electrodes, and the second electrode group includes a second working electrode and a second pair of electrodes; the first pair of electrodes forms a circuit with the first working electrode, and the second pair of electrodes forms a circuit with the second working electrode; The first electrode assembly is used to determine a first physiological parameter when the first electrode assembly is implanted in subcutaneous tissue, specifically including: The first working electrode is used to determine a first physiological parameter when the first working electrode is implanted in subcutaneous tissue; The second electrode assembly is used to determine a second physiological parameter when the second electrode assembly is implanted in subcutaneous tissue, specifically including: The second working electrode is used to determine a second physiological parameter when the second working electrode is implanted in subcutaneous tissue; The first electrode group and the second electrode group are also used to determine electrocardiogram signals when the first electrode group and the second electrode group are implanted in subcutaneous tissue, specifically including: The first working electrode, the first pair of electrodes, and the second working electrode are also used to determine electrocardiogram signals when the first working electrode, the first pair of electrodes, and the second working electrode are implanted in subcutaneous tissue.
17. The electronic device according to claim 15, characterized in that, The first electronic device further includes a microcontroller unit (MCU); the first electrode group includes a first working electrode, a first reference electrode, and a first pair of electrodes; the second electrode group includes a second working electrode, a second reference electrode, and a second pair of electrodes. The first electrode assembly is used to determine a first physiological parameter when the first electrode assembly is implanted in subcutaneous tissue, specifically including: The first working electrode is used to generate a first current when the first working electrode is implanted in subcutaneous tissue; The first reference electrode is used to control the voltage of the first working electrode; The first pair of electrodes is used to form a circuit with the first working electrode; The MCU is used to determine the first physiological parameter based on the first current; The second electrode assembly is used to determine a second physiological parameter when the second electrode assembly is implanted in subcutaneous tissue, specifically including: The second working electrode is used to generate a second current when the second working electrode is implanted in subcutaneous tissue; The second reference electrode is used to control the voltage of the second working electrode; The second pair of electrodes is used to form a circuit with the second working electrode; The MCU is used to determine the second physiological parameter based on the second current.
18. The electronic device according to claim 17, characterized in that, The first electrode group and the second electrode group are also used to determine electrocardiogram signals when the first electrode group and the second electrode group are implanted in subcutaneous tissue, specifically including: Any two electrodes in the first electrode group and any one electrode in the second electrode group are used to determine electrocardiogram signals when the first electrode group and the second electrode group are implanted in subcutaneous tissue. or, Any one electrode in the first electrode group and any two electrodes in the second electrode group are used to determine electrocardiogram signals when the first electrode group and the second electrode group are implanted in subcutaneous tissue.
19. The electronic device according to claim 18, characterized in that, Any two electrodes from the first electrode group and any one electrode from the second electrode group are used to determine electrocardiogram signals when the first electrode group and the second electrode group are implanted in subcutaneous tissue, specifically including: When the first pair of electrodes is connected to the right leg drive circuit, the first pair of electrodes, the first working electrode, and the second reference electrode are used to determine the electrocardiogram signal when the first electrode group and the second electrode group are implanted in the subcutaneous tissue.
20. The electronic device according to claim 17, characterized in that, The first electrode group further includes a first ECG electrode and a second ECG electrode, and the second electrode group further includes a third ECG electrode. The second ECG electrode is connected to a right leg drive circuit. The first electrode group and the second electrode group are also used to determine electrocardiogram signals when the first electrode group and the second electrode group are implanted in subcutaneous tissue, specifically including: The first, second, and third electrocardiogram (ECG) electrodes are used to determine ECG signals when the first and second electrode groups are implanted in subcutaneous tissue.
21. The electronic device according to any one of claims 15-20, characterized in that, The first electronic device further includes a first microneedle sensor and a second microneedle sensor, wherein the first microneedle sensor includes the first electrode group and the second microneedle sensor includes the second electrode group.
22. The electronic device according to any one of claims 15-20, characterized in that, The first electronic device further includes a first array sensor and a second array sensor, wherein the first array sensor includes the first electrode group and the second array sensor includes the second electrode group.
23. The electronic device according to any one of claims 15-22, characterized in that, The first electronic device also includes a communication module; The communication module is used to send the first physiological parameter to the second electronic device; The communication module is also used to send the electrocardiogram signal to the second electronic device.
24. A measuring circuit, characterized in that, It includes a first electrode group, a second electrode group, a first electrochemical circuit module, a second electrochemical circuit module, an electrocardiogram circuit module, and a microcontroller unit (MCU). The first electrode group is connected to the first electrochemical circuit module, and the first electrode group is also connected to the electrocardiogram circuit module; The second electrode group is connected to the second electrochemical circuit module, and the second electrode group is also connected to the electrocardiogram circuit module; The MCU is connected to the first electrochemical circuit module, the second electrochemical circuit module, and the electrocardiogram circuit module. The first electrode group is used to generate a first current signal; The first electrode group is also used to transmit the first current signal to the first electrochemical circuit module; The first electrochemical circuit module is used to determine the second current signal based on the first current signal; The first electrochemical circuit module is also used to transmit the second current signal to the MCU; The MCU is used to determine a first physiological parameter based on the second current signal; The second electrode group is used to generate a third current signal; The second electrode group is also used to transmit the third current signal to the second electrochemical circuit module; The second electrochemical circuit module is used to determine a fourth current signal based on the third current signal; The second electrochemical circuit module is also used to transmit the fourth current signal to the MCU; The MCU is used to determine the second physiological parameter based on the fourth current signal; The first electrode group and the second electrode group are used to acquire the first electrocardiogram signal; The first electrode group and the second electrode group are also used to transmit the first electrocardiogram signal to the electrocardiogram circuit module; The ECG circuit module is used to determine a second ECG signal based on the first ECG signal; The ECG circuit module is also used to transmit the second ECG signal to the MCU.
25. The circuit according to claim 24, characterized in that, The first electrode group includes a first working electrode, a first reference electrode, and a first pair of electrodes; the first electrochemical circuit module includes a first potentiostat circuit and a first transimpedance circuit; the first potentiostat circuit is used to control the voltage of the first working electrode and the first reference electrode; the first transimpedance circuit is used to amplify the first current signal. The first electrode assembly is connected to the first electrochemical circuit module, specifically including: The first working electrode, the first reference electrode, and the first pair of electrodes are connected to the first potentiostat circuit. The first working electrode is connected to the first transimpedance circuit.
26. The circuit according to claim 25, characterized in that, The second electrode assembly includes a second working electrode, a second reference electrode, and a second pair of electrodes; the second electrochemical circuit module includes a second potentiostat circuit and a second transimpedance circuit; the second potentiostat circuit is used to control the voltage of the second working electrode and the second reference electrode; the second transimpedance circuit is used to amplify the third current signal; The second electrode assembly is connected to the second electrochemical circuit module, specifically including: The second working electrode, the second reference electrode, and the second pair of electrodes are connected to the second potentiostat circuit. The second working electrode is connected to the second transimpedance circuit.
27. The circuit according to claim 26, characterized in that, The ECG circuit module includes a right leg drive circuit, an amplifier circuit, and a filter circuit, with the amplifier circuit connected to the filter circuit. The right leg drive circuit is used to cancel common-mode signals, the amplifier circuit is used to amplify the first ECG signal, and the filter circuit is used for filtering. The first electrode group is connected to the ECG circuit module, specifically including: The first working electrode is connected to the amplifier circuit, and the first pair of electrodes is connected to the right leg drive circuit; The second electrode group is connected to the ECG circuit module, specifically including: The second reference electrode is connected to the amplifier circuit module; The first electrode group and the second electrode group are used to acquire the first electrocardiogram signal, specifically including: The first working electrode and the second reference electrode are used to acquire the first electrocardiogram signal; The first electrode group and the second electrode group are further used to transmit the first electrocardiogram signal to the electrocardiogram circuit module, specifically including: The first working electrode and the second reference electrode are used to transmit the first electrocardiogram signal to the amplification circuit; The ECG circuit module is used to determine a second ECG signal based on the first ECG signal, specifically including: The amplifier circuit is used to amplify the first electrocardiogram signal and then transmit it to the filter circuit; The filtering circuit is used to determine the second electrocardiogram signal based on the amplified first electrocardiogram signal; The ECG circuit module is further configured to transmit the second ECG signal to the MCU, specifically including: The filtering circuit is also used to transmit the second electrocardiogram signal to the MCU.
28. The circuit according to claim 26, characterized in that, The first electrode group further includes a first ECG electrode and a second ECG electrode, and the second electrode group further includes a third ECG electrode. The ECG circuit module includes a right leg drive circuit, an amplifier circuit, and a filter circuit. The amplifier circuit is connected to the filter circuit. The right leg drive circuit is used to cancel common-mode signals, the amplifier circuit is used to amplify the first ECG signal, and the filter circuit is used for filtering. The first electrode group is connected to the ECG circuit module, specifically including: The first ECG electrode is connected to the amplification circuit, and the second ECG electrode is connected to the right leg drive circuit; The second electrode group is connected to the ECG circuit module, specifically including: The third electrocardiogram electrode is connected to the amplifier circuit module; The first electrode group and the second electrode group are used to transmit electrocardiogram (ECG) signals to the ECG circuit module, specifically including: The first and third electrocardiogram electrodes are used to transmit the electrocardiogram signal to the amplification circuit. The ECG circuit module is used to determine a second ECG signal based on the first ECG signal, specifically including: The amplifier circuit is used to amplify the first electrocardiogram signal and then transmit it to the filter circuit; The filtering circuit is used to determine the second electrocardiogram signal based on the amplified first electrocardiogram signal; The ECG circuit module is further configured to transmit the second ECG signal to the MCU, specifically including: The filtering circuit is also used to transmit the second electrocardiogram signal to the MCU.
29. A measuring circuit, characterized in that, It includes a first electrode group, a second electrode group, a first switching switch, a first electrochemical circuit module, an electrocardiogram circuit module, and a microcontroller unit (MCU); the first switching switch includes a first set of input ports, a second set of input ports, and a first set of output ports, and the first switching switch is used to connect the first set of input ports or the second set of input ports; The first electrode group is connected to the first input port, and the first electrode group is connected to the ECG circuit module; The second electrode group is connected to the second input port, and the second electrode group is also connected to the ECG circuit module; The first set of output ports is connected to the first electrochemical circuit module; The MCU is connected to the first electrochemical circuit module and the electrocardiogram circuit module; The first electrode group is used to generate a first current signal; The first electrode group is also used to transmit the first current signal to the first switching switch; The first switching switch is used to transmit the first current signal to the first electrochemical circuit module when the first set of input ports is turned on; The first electrochemical circuit module is used to determine the second current signal based on the first current signal; The first electrochemical circuit module is also used to send the second current signal to the MCU; The MCU is used to determine a first physiological parameter based on the second current signal; The second electrode group is used to generate a third current signal; The second electrode group is also used to transmit the third current signal to the first switching switch; The first switching switch is used to transmit the third current signal to the first electrochemical circuit module when the second set of input ports is turned on; The first electrochemical circuit module is also used to determine a fourth current signal based on the third current signal; The first electrochemical circuit module is also used to transmit the fourth current signal to the MCU; The MCU is used to determine the second physiological parameter based on the fourth current signal; The first electrode group and the second electrode group are used to acquire the first electrocardiogram signal; The first electrode group and the second electrode group are also used to transmit the first electrocardiogram signal to the electrocardiogram circuit module; The ECG circuit module is used to determine a second ECG signal based on the first ECG signal; The ECG circuit module is also used to transmit the second ECG signal to the MCU.
30. The circuit according to claim 29, characterized in that, The first electrode group includes a first working electrode, a first reference electrode, and a first pair of electrodes; the first group of input ports includes a first input port, a second input port, and a third input port; the second electrode group includes a second working electrode, a second reference electrode, and a second pair of electrodes; the second group of input ports includes a fourth input port, a fifth input port, and a sixth input port. The first working electrode is connected to the first input port, the first reference electrode is connected to the second input port, and the first pair of electrodes is connected to the third input port; The second working electrode is connected to the fourth input port, the second reference electrode is connected to the fifth input port, and the second pair of electrodes is connected to the sixth input port.
31. The circuit according to claim 30, characterized in that, The first set of output ports includes a first output port, a second output port, and a third output port; The first switch is used to connect the first group of input ports, specifically including: The first output port is used to connect to the first input port, the second output port is used to connect to the second input port, and the third output port is used to connect to the third input port; The first switch is used to connect the second group of input ports, specifically including: The first output port is used to connect to the fourth input port, the second output port is used to connect to the fifth input port, and the third output port is used to connect to the sixth input port.
32. The circuit according to claim 31, characterized in that, The first electrochemical circuit module includes a first potentiostat circuit and a first transimpedance circuit; the first potentiostat circuit is used to control the voltage of the first working electrode and the first reference electrode; the first transimpedance circuit is used to amplify the first current signal. The first set of output ports is connected to the first electrochemical circuit module, specifically including: The first output port, the second output port, and the third output port are connected to the first potentiostat circuit. The first output port is connected to the first transimpedance circuit.
33. A chip system, characterized in that, The chip system, applied to a first electronic device, comprises a processing circuit and an interface circuit, wherein the interface circuit is configured to receive code instructions and transmit them to the processing circuit, and the processing circuit is configured to execute the code instructions to cause the chip system to perform the method described in any one of claims 1-14.
34. A readable storage medium comprising instructions, characterized in that, When the instructions are executed on the first electronic device, the first electronic device performs the method of any one of claims 1-14.