Two-fluid nozzle

Abstract

The present invention provides a nozzle unit for supplying medicinal liquid and gas into the abdominal cavity. The nozzle unit according to one embodiment may comprise: a nozzle for discharging the medicinal liquid; a nozzle cap coupled to the nozzle to form a mixing space therein in which the medicinal liquid and the gas are mixed, and having a spray hole formed in the lower part thereof for spraying a fluid in which the medicinal liquid and the gas are mixed; a first conduit inserted into the nozzle for transferring the medicinal liquid to the nozzle; and a second conduit surrounding the first conduit and inserted into the nozzle cap for transferring the gas to the mixing space, wherein a space formed between the first conduit and the second conduit may be in fluid communication with the mixing space.

Description

two-fluid nozzle

[0001] The present invention relates to a two-fluid nozzle, and more particularly, to a two-fluid nozzle for spraying a drug such as an anticancer agent into the abdominal cavity to treat cancer, etc. in a patient.

[0002] Cross-reference to related applications

[0003] This application claims priority to Republic of Korea Patent Application No. 10-2024-0050565, filed April 16, 2024, the entire contents of which are incorporated herein by reference.

[0004] Typically, when cancer cells metastasize within the abdominal cavity, drugs are administered orally or intravascularly. However, these methods often have limited efficacy in suppressing or eliminating metastatic cancer cells within the abdominal cavity. One solution to this problem is intraperitoneal chemotherapy (IPC). IPC involves directly injecting drugs into the abdominal cavity to suppress or eliminate cancer cells.

[0005] In conventional intraperitoneal chemotherapy, the nozzles used to inject drugs into the abdominal cavity are typically 10 mm or larger in diameter. When performing intraperitoneal chemotherapy using such large nozzles, it is difficult for the nozzles to accurately reach areas with severe lesions within the abdominal cavity. Furthermore, the nozzle's maneuverability within the abdominal cavity is significantly reduced, making it difficult to target cancer cells from various directions.

[0006] Furthermore, conventional intraperitoneal chemotherapy requires the patient's abdomen to be perforated, as the drug is directly injected into the abdominal cavity. Larger diameters of the nozzle used to inject the drug or the trocar used to expel gas from the abdominal cavity result in larger perforations. This can lead to subsequent adverse effects in patients after intraperitoneal chemotherapy. Furthermore, larger nozzles make it difficult for the practitioner to accurately deliver the drug to heavily lesioned areas, reducing the effectiveness of cancer cell removal or suppression.

[0007] The purpose of the present invention is to provide a nozzle unit capable of efficiently delivering a drug solution to a lesion site.

[0008] In addition, the present invention aims to provide a nozzle unit that can approach a lesion site from various directions.

[0009] In addition, the present invention aims to provide a nozzle unit capable of intensively delivering a medicinal solution to a severely lesioned area.

[0010] The problems to be solved by the present invention are not limited to the problems described above, and problems not mentioned can be clearly understood by a person having ordinary skill in the art to which the present invention pertains from this specification and the attached drawings.

[0011] The present invention provides a nozzle unit for supplying a drug solution and gas into an abdominal cavity. In one embodiment, the nozzle unit includes a nozzle for discharging the drug solution, a nozzle cap coupled with the nozzle to form a mixing space inside where the drug solution and the gas are mixed, and having a spray hole formed at a lower portion for spraying a fluid in which the drug solution and the gas are mixed, a first conduit inserted into the nozzle and for delivering the drug solution to the nozzle, and a second conduit surrounding the first conduit and inserted into the nozzle cap to deliver the gas to the mixing space, wherein a space formed by combining the first conduit and the second conduit can be in fluid communication with the mixing space.

[0012] In one embodiment, the outer diameter of the second conduit may be 5 mm.

[0013] In one embodiment, the nozzle may include a first body having an insertion groove formed therein into which the first conduit is inserted, and a second body having a discharge hole formed to protrude downward from the first body and fluidly communicating with the insertion groove.

[0014] In one embodiment, the second conduit is combined with the first body to form a space in which the gas flows, and the interspace, the space in between, and the mixing space can be in fluid communication with each other.

[0015] In one embodiment, the second body may be formed with a gas guide groove that guides the flow direction of the gas flowing from the separation space to the mixing space.

[0016] In one embodiment, the gas guide groove may be formed in a vertical direction when viewed from the front.

[0017] In one embodiment, the gas guide groove may be arranged in a diagonal direction when viewed from the front.

[0018] In one embodiment, the spaced apart space may have an arcuate shape when viewed from above.

[0019] In one embodiment, the spaced apart space may have a rectangular shape when viewed from above.

[0020] According to one embodiment, the injection holes are formed in a plurality along the circumferential direction of the nozzle cap at the lower portion of the nozzle cap, and may be formed to be inclined in a direction toward the outside of the nozzle cap from the upper portion of the injection holes to the lower portion of the injection holes.

[0021] In one embodiment, the nozzle unit is used for intraperitoneal chemotherapy, the liquid is an anticancer agent, and the gas may be air or carbon dioxide.

[0022] According to one embodiment of the present invention, a drug solution can be efficiently delivered to a lesion site.

[0023] Additionally, according to one embodiment of the present invention, the drug can be delivered by approaching the lesion site from various directions and angles.

[0024] Additionally, according to one embodiment of the present invention, the drug can be delivered by targeting it intensively to an area with a severe lesion.

[0025] In addition, according to one embodiment of the present invention, the spraying efficiency of the drug can be improved by controlling the degree of atomization of the drug provided to the lesion area.

[0026] Additionally, according to one embodiment of the present invention, the perforation size can be reduced to minimize side effects on the patient.

[0027] Additionally, according to one embodiment of the present invention, the convenience of use for the operator can be improved.

[0028] The effects of the present invention are not limited to the effects described above, and effects not mentioned can be clearly understood by a person skilled in the art to which the present invention pertains from this specification and the attached drawings.

[0029] FIG. 1 is a perspective view schematically showing a nozzle unit according to one embodiment of the present invention.

[0030] Figure 2 is an exploded perspective view schematically showing a nozzle unit according to one embodiment.

[0031] Figure 3 is a partially enlarged view schematically showing a nozzle section according to one embodiment.

[0032] Figure 4 is a schematic drawing showing a cross-section taken along line XX of Figure 3 as viewed from above.

[0033] Figures 5 and 6 are perspective views schematically showing a nozzle according to one embodiment.

[0034] Figure 7 is a perspective view schematically showing a nozzle cap according to one embodiment.

[0035] Fig. 8 is a cross-sectional view schematically showing a nozzle cap according to one embodiment.

[0036] Figures 9 and 10 are perspective views schematically showing a nozzle according to another embodiment.

[0037] Figures 11 and 12 are schematic drawings showing a nozzle cap according to another embodiment.

[0038] Hereinafter, embodiments of the present invention will be described in detail with reference to the attached drawings so that those skilled in the art can easily practice the present invention. Embodiments of the present invention can be modified and implemented in various forms and are not limited to the embodiments described below. In addition, the embodiments described below are provided so that those skilled in the art can more completely explain the present invention. Therefore, the shapes of components in the drawings are exaggerated to emphasize clear explanation. In addition, when describing preferred embodiments of the present invention in detail, if it is determined that a specific description of a related known function or configuration may unnecessarily dilute the gist of the present invention, a detailed description thereof will be omitted. In addition, the same reference numerals are used throughout the drawings for parts having similar functions and operations.

[0039] To "include" a component, unless otherwise specifically stated, does not exclude other components, but rather implies that other components may be included. Specifically, terms such as "include" or "have" should be understood to mean features, numbers, steps, operations, components, parts, or combinations thereof described in the specification, and not to exclude in advance the possibility of the presence or addition of one or more other features, numbers, steps, operations, components, parts, or combinations thereof.

[0040] Singular expressions include plural expressions unless the context clearly indicates otherwise. Furthermore, terms such as "first" and "second" may be used to describe various components, but these components are not limited by these terms. These terms may be used to distinguish one component from another. For example, within the scope of the present invention, a first component may be referred to as a "second component," and similarly, a second component may also be referred to as a "first component."

[0041] Unless otherwise defined, all terms used herein, including technical or scientific terms, have the same meaning as commonly understood by those of ordinary skill in the art to which this invention pertains. Terms defined in commonly used dictionaries should be interpreted in a way consistent with their meaning within the context of the relevant technology, and shall not be interpreted in an idealized or overly formal sense unless explicitly defined below.

[0042] The nozzle unit according to one embodiment of the present invention can be used to spray a therapeutic liquid. In particular, the nozzle unit according to one embodiment can be used in intraperitoneal chemotherapy, which directly sprays a liquid medicine onto cancer cells to suppress or eliminate cancer cells located within the abdominal cavity. Furthermore, the nozzle according to one embodiment can be a two-fluid nozzle that mixes a liquid medicine and a gas and sprays the atomized fluid into the abdominal cavity. However, the present invention is not limited thereto, and the nozzle unit according to one embodiment can be applied in various ways to surgeries that directly spray a liquid medicine and a gas onto a diseased area to suppress or eliminate a disease-causing factor. Hereinafter, for the convenience of understanding, the nozzle unit according to one embodiment will be described in detail with reference to the attached drawings, taking as an example a case where it is used in intraperitoneal chemotherapy.

[0043] Fig. 1 is a perspective view schematically showing a nozzle unit according to one embodiment of the present invention. Fig. 2 is an exploded perspective view schematically showing a nozzle unit according to one embodiment.

[0044] Referring to FIGS. 1 and 2, a nozzle unit (1) according to one embodiment may include a nozzle portion (10), a connection portion (20), a gas supply port (30), and a liquid supply port (40).

[0045] In one embodiment, the nozzle unit (10) mixes the liquid and gas received from the gas supply port (30) and the liquid supply port (40) described below and sprays them into the abdominal cavity. The nozzle unit (10) may include a conduit unit (100), a nozzle (200), and a nozzle cap (300). The conduit unit (100) includes a first conduit (120) through which the liquid flows and a second conduit (140) through which the gas flows. A detailed description of the nozzle unit (10) will be described below.

[0046] In one embodiment, a connecting portion (20) connects a nozzle portion (10) and a gas supply port (30) to each other. More specifically, one end of the connecting portion (20) is connected to the nozzle portion (10), and the other end is connected to one end of the gas supply port (30). For example, one end of the connecting portion (20) is connected to the other end of the second conduit (140). The connecting portion (20) can seal the second conduit (140) to prevent gas supplied to the second conduit (140) from leaking out. In addition, the other end of the connecting portion (20) can have a shape corresponding to one end of the gas supply port (30). In addition, the connecting portion (20) can seal the gas supply port (30).

[0047] The gas supply port (30) may have a 3-way configuration. In one embodiment, one end of the gas supply port (30) is connected to the other end of the connection portion (20) as described above, and the other end of the gas supply port (30) is connected to one end of the chemical supply port (40). The branch end of the gas supply port (30) is connected to a gas supply portion (not shown) that is not illustrated. The gas supply portion (not shown) supplies gas to the gas supply port (30). The gas supply portion (not shown) may include a gas source (not shown) that provides gas, a hose (not shown) through which gas flows, a gas valve (not shown) including an on-off valve or a flow control valve, and a gas pump (not shown). In one embodiment, the gas supplied to the gas supply port (30) may be carbon dioxide or air.

[0048] For example, a gas supply unit (not shown) may be connected to a trocar (not shown) inserted into an independently perforated portion of the abdominal cavity to discharge gas present within the abdominal cavity to the outside of the abdominal cavity, and the discharged gas may be re-supplied through a hose to form a gas circulation system that simultaneously supplies and circulates the gas. The point at which the discharged gas using the trocar (not shown) is connected to the hose is not particularly limited. Accordingly, those skilled in the art will be able to apply various modified examples of the gas circulation system.

[0049] One end of the drug supply port (40) according to one embodiment is connected to the other end of the gas supply port (30) as described above, and the other end of the drug supply port (40) is connected to a drug supply unit (not shown). The drug supply unit (not shown) supplies the drug to the drug supply port (40). The drug supply port (40) supplies the drug to the nozzle unit (10). The drug according to one embodiment may be an anticancer agent for treating cancer cells metastasized in the abdominal cavity. For example, the drug supply unit (not shown) may be a syringe. The drug supply unit (not shown) may supply the drug at a constant pressure.

[0050] Fig. 3 is a partially enlarged view schematically showing a nozzle portion according to one embodiment. Figs. 4 and 5 are perspective views schematically showing a nozzle according to one embodiment. Fig. 6 is a perspective view schematically showing a nozzle cap according to one embodiment. Fig. 7 is a cross-sectional view schematically showing a nozzle cap according to one embodiment. Fig. 8 is a drawing schematically showing a cross-section taken along line II of Fig. 3 as viewed from above.

[0051] Hereinafter, a nozzle unit according to one embodiment of the present invention will be described in detail with reference to FIGS. 1 to 8.

[0052] According to one embodiment, a chemical liquid flows inside the first conduit (120). The first conduit (120) is connected to the chemical liquid supply port (40). More specifically, the first conduit (120) passes through the connection part (20) and the gas supply port (30), one end of which is inserted into the nozzle (200), and the other end of which is connected to one end of the chemical liquid supply port (40). The chemical liquid supplied by the above-described chemical liquid supply part (not shown) flows into the first conduit (120) through the chemical liquid supply port (40) and is delivered to the nozzle (200) connected to the first conduit (120). In addition, the end shape of the first conduit (120) may be formed in a stepped shape. For example, the cross-sectional shape of the end of the first conduit (120) may be formed in a structure that is recessed toward the inner surface of the first conduit (120).

[0053] In one embodiment, gas flows inside the second conduit (140). The diameter of the second conduit (140) is relatively larger than the diameter of the first conduit (120). For example, the outer diameter of the second conduit (140) may be 5 mm. The second conduit (140) surrounds the first conduit (120). More specifically, the second conduit (140) surrounds the outer side of the first conduit (120) at a predetermined distance from the first conduit (120). That is, the inner side of the second conduit (140) is arranged at a predetermined distance from the outer side of the first conduit (120). Accordingly, the second conduit (140) is combined with the first conduit (120) to form an intervening space (S1). As described above, the other end of the second conduit (140) is connected to one end of the connecting portion (20). In addition, the connecting portion (20) is connected to the gas supply port (30). Accordingly, the gas supplied from the gas supply port (30) is delivered to the interspace (S1) through the connecting portion (20).

[0054] One end of the second conduit (140) is inserted into the nozzle cap (300). For example, the second conduit (140) may be inserted into the nozzle cap (300) in a screw-joint manner. Although not shown, screw threads may be formed on the inner surface of the nozzle cap (300) to allow the second conduit (140) to be inserted therein. However, the present invention is not limited thereto, and the second conduit (140) may be inserted into and fixed to the nozzle cap (300) in various ways.

[0055] In addition, the end shape of the second conduit (140) may be formed in a stepped manner. For example, the end of the second conduit (140) may be formed in a structure in which the end is recessed toward the outer surface of the second conduit (140). For example, the inner surface of the end of the second conduit (140) may be formed in a stepped manner. Accordingly, the second conduit (140) is arranged to be spaced apart from the nozzle (200) by a certain distance. That is, the inner surface of the second conduit (140) is spaced apart from the outer surface of the nozzle (200).

[0056] According to one embodiment, a nozzle (200) discharges a liquid. The nozzle (200) includes a first body (220) and a second body (240). The first body (220) and the second body (240) may be formed integrally.

[0057] The first body (220) is positioned above the second body (240). That is, the first body (220) is positioned closer to the first conduit (120) than the second body (240). An insertion groove (222) is formed inside the first body (220). The first conduit (120) is inserted into the insertion groove (222). The end of the insertion groove (222) may be formed to be stepped. The stepped portion of the insertion groove (222) may have a shape corresponding to the shape of the stepped end of the first conduit (120).

[0058] According to one embodiment, the first body (220) may be provided in a generally triangular shape when viewed from above. For example, the first body (220) may be formed so that each corner is rounded. The first body (220) is combined with the second conduit (140) to form a separation space (S2). The separation space (S2) according to one embodiment may have a generally arcuate shape when viewed from above, as illustrated in FIG. 4, due to the triangular shape of the first body (220). The separation space (S2) is in fluid communication with the aforementioned interspace (S1). Accordingly, gas transmitted to the interspace (S1) can flow through the separation space (S2).

[0059] According to one embodiment, the second body (240) is formed to protrude downward from the first body (220). More specifically, the second body (240) is formed to protrude in a direction away from the first body (220). In addition, a plurality of discharge holes (242) are formed in the second body (240). The plurality of discharge holes (242) may be arranged to be spaced apart from each other by a certain distance. In addition, some of the plurality of discharge holes (242) may be formed to face diagonally when viewed from the front. Others of the plurality of discharge holes (242) may be formed to face vertically. The discharge hole (242) may penetrate the second body (240). In addition, the discharge hole (242) may be in fluid communication with the insertion groove (222) by penetrating the second body (240). In addition, the discharge hole (242) can pass through the second body (240) and be in fluid communication with the mixing space (S3) described later. Accordingly, the liquid that has flowed into the first conduit (120) can flow into the mixing space (S3) through the nozzle (200).

[0060] According to one embodiment, the second body (240) may have a shape in which the width decreases from the top to the bottom. For example, the second body (240) may be formed to be inclined in a direction toward the injection hole (302) formed in the nozzle cap (300) described below.

[0061] The first body (220) and the second body (240) are combined with the nozzle cap (300) described below to form a mixing space (S3). As described above, the first body (220) is spaced apart from the second conduit (140) by a certain distance. In addition, the first body (220) and the second body (240) are each spaced apart from the nozzle cap (300). More specifically, the outer surfaces of the first body (220) and the second body (240) are each arranged to be spaced apart from the inner surface of the nozzle cap (300) by a certain distance. The first body (220), the second body (240), and the nozzle cap (300) are combined with each other to form a mixing space (S3). The mixing space (S3) is in fluid communication with the spaced apart space (S2).

[0062] In addition, a gas guide groove (244) may be formed in the second body (240) according to one embodiment. The gas guide groove (244) is formed on a side surface of the second body (240). The gas guide groove (244) may be formed in a structure that is recessed into the side surface of the second body (240). The gas guide groove (244) according to one embodiment may be formed in a vertical direction when viewed from the front. In addition, a plurality of gas guide grooves (244) may be formed. The gas guide grooves (244) may be formed between each of the discharge holes (242). The gas guide grooves (244) guide the flow direction of the gas. More specifically, the gas guide grooves (244) may guide the flow direction of the gas flowing from the aforementioned separation space (S2) to the mixing space (S3). That is, the gas guide groove (244) can guide the gas existing in the separation space (S2) to efficiently flow to the mixing space (S3) along the gas guide groove (244) formed in the second body (240).

[0063] According to one embodiment, the nozzle cap (300) may have a cylindrical shape with an open upper portion. However, the shape of the nozzle cap (300) is not limited thereto, and may be provided in various shapes. As described above, a second conduit (140) is inserted into the nozzle cap (300). Accordingly, a conduit portion (100) and a nozzle (200) are positioned inside the nozzle cap (300). At least one spray hole (302) is formed at the lower end of the nozzle cap (300). The spray hole (302) may penetrate the lower end of the nozzle cap (300).

[0064] As described above, the liquid medicine flows into the mixing space (S3) through the first conduit (120) and the discharge hole (242) of the nozzle (200), and the gas flows into the mixing space (S3) through the interspace (S1) and the separation space (S2) and is guided along the gas guide groove (244). The liquid medicine and gas delivered to the mixing space (S3) are mixed in the mixing space (S3) and atomized in the process of being sprayed through the spray hole (302).

[0065] For example, the size of the mixing space (S3) can be adjusted by adjusting the degree of insertion between the second conduit (140) and the nozzle cap (300) described above. For example, the more the nozzle cap (300) and the second conduit (140) are coupled to a minimum, the larger the size of the mixing space (S3) and the larger the size of the fluid communication space between the mixing space (S3) and the injection hole (302) can be. In this case, the degree of atomization of the mixed fluid of the chemical liquid and the gas sprayed through the mixing space (S3) can be increased. That is, a finer mixed fluid of the chemical liquid and the gas can be sprayed into the abdominal cavity. Conversely, the more the nozzle cap (300) and the second conduit (140) are coupled to a maximum extent (i.e., to the extent that a part of the outer surface of the first body (220) comes into contact with a part of the inner surface of the nozzle cap (300), the degree of atomization of the mixed fluid sprayed through the mixing space (S3) can be decreased. That is, by adjusting the size of the mixing space (S3), the degree of atomization of the mixed fluid of the drug and gas sprayed through the injection hole (302) can be controlled. In this case, the degree of atomization of the mixed fluid of the drug and gas sprayed can be controlled according to the degree of metastasis of cancer cells in the abdominal cavity, thereby efficiently removing or suppressing cancer cells.

[0066] Furthermore, according to the above-described embodiment, since the diameter of the second conduit (140) is provided as 5 mm, the diameter of the intraperitoneal perforation can be drastically reduced compared to conventional methods. Accordingly, subsequent complications and side effects in patients due to perforation after chemotherapy can be minimized.

[0067] Furthermore, according to the above-described embodiment, since the diameter of the second conduit (140) is reduced, the maneuverability of the nozzle unit (10) within the abdominal cavity can be improved. Accordingly, the lesion site within the abdominal cavity can be easily accessed from various directions or angles, and the mixed fluid of the drug and gas can be intensively sprayed by targeting the lesion site within the abdominal cavity. In other words, cancer cells metastasized within the abdominal cavity can be more efficiently suppressed and removed.

[0068] Additionally, according to the above-described embodiment, since the diameter of the second conduit (140) is reduced, grip fatigue of the operator is significantly reduced and user convenience is improved when performing intraperitoneal chemotherapy. Accordingly, intraperitoneal chemotherapy can be performed more efficiently, thereby enhancing the efficiency of the procedure.

[0069] Below, a nozzle unit according to another embodiment of the present invention will be described in detail. Except where additional descriptions are provided, the nozzle unit described below has a structure and function largely identical or similar to the nozzle unit described with reference to FIGS. 1 to 8. Therefore, descriptions of overlapping details will be omitted.

[0070] Figures 9 and 10 are perspective views schematically showing a nozzle according to another embodiment.

[0071] Referring to FIGS. 9 and 10, a nozzle (200) according to one embodiment may include a first body (220) and a second body (240). The first body (220) and the second body (240) according to one embodiment may be provided in a generally circular shape when viewed from above. According to one embodiment, a protrusion (224) may be formed on a side of the first body (220). A plurality of protrusions (224) may be formed. The plurality of protrusions (224) may be formed to be spaced apart from each other at a predetermined interval along the periphery of the first body (220). The number of the plurality of protrusions (224) may vary. The side surface of the protrusions (224) may be formed to be round when viewed from above. The plurality of protrusions (224) are combined with the first body (220) to form a separation space (S2) through which gas flows. According to one embodiment, the separation space (S2) may have a generally rectangular shape when viewed from above. Gas transmitted through the interspace may flow through the separation space (S2).

[0072] According to one embodiment, the second body (240) has a generally cylindrical shape, but its lower portion may be provided with an inclined shape. More specifically, the lower portion of the second body (240) may be formed in a shape in which the diameter decreases from the upper portion to the lower portion (i.e., in the direction away from the first body (220)).

[0073] A gas guide groove (244) may be formed in the second body (240). According to one embodiment, a plurality of gas guide grooves (244) may be formed. The gas guide grooves (244) may be formed in a diagonal direction when viewed from the front. In addition, the arrangement directions of the plurality of gas guide grooves (244) may be combined to form a spiral shape. A plurality of discharge holes (242) formed in the second body (240) may be formed on the gas guide grooves (244). In addition, the upper ends of the gas guide grooves (244) may be formed on a straight line corresponding to the separation space (S2) when viewed from the front. Accordingly, the gas flowing through the separation space (S2) may be smoothly guided to the gas guide grooves (244) and mixed more efficiently with the chemical liquid in the mixing space.

[0074] Figures 11 and 12 are schematic drawings showing a nozzle cap according to another embodiment.

[0075] Referring to FIGS. 11 and 12, a nozzle cap (300) according to one embodiment may have a plurality of spray holes (302). The plurality of spray holes (302) are formed along the circumferential direction of the nozzle cap (300). In addition, the plurality of spray holes (302) formed along the circumferential direction of the nozzle cap (300) are arranged at a constant interval from each other. In addition, a spray hole (302) may also be formed at the lower central portion of the nozzle cap (300). The spray hole (302) formed at the lower central portion of the nozzle cap (300) may be formed in a vertical direction when viewed from the front, and the spray hole (302) formed along the circumferential direction of the nozzle cap (300) may be formed to be inclined when viewed from the front. More specifically, the spray hole (302) formed along the circumferential direction of the nozzle cap (300) may be formed to be inclined in a direction toward the outside of the nozzle cap (300) from the top to the bottom. That is, the injection hole (302) formed along the circumferential direction of the nozzle cap (300) may be formed to be inclined in a direction away from the injection hole (302) formed in the central portion of the nozzle cap (300) as it goes downward. Accordingly, the chemical liquid flowing through the injection hole (302) formed in the nozzle cap (300) can be more efficiently mixed with the gas in the mixing space.

[0076] The detailed description above is illustrative of the present invention. Furthermore, the above description illustrates and describes preferred embodiments of the present invention, and the present invention can be used in various other combinations, modifications, and environments. In other words, changes or modifications are possible within the scope of the inventive concept disclosed in this specification, the scope equivalent to the written disclosure, and / or the scope of technology or knowledge in the art. The written embodiments illustrate the best possible state for implementing the technical idea of ​​the present invention, and various modifications required for specific application fields and uses of the present invention are also possible. Therefore, the detailed description of the invention above is not intended to limit the present invention to the disclosed embodiments. Furthermore, the appended claims should be construed to include other embodiments.

[0077] According to the two-fluid nozzle according to embodiments of the present invention, the drug can be efficiently delivered by approaching the lesion site from various directions and angles.

Claims

1. A nozzle unit that supplies intraperitoneal liquid and gas. A nozzle for discharging the above-mentioned liquid; A nozzle cap having a mixing space formed inside the nozzle in combination with the nozzle, in which the chemical liquid and the gas are mixed, and a spray hole formed at the bottom for spraying a fluid in which the chemical liquid and the gas are mixed; A first conduit inserted into the nozzle and delivering the liquid to the nozzle; and A second conduit surrounding the first conduit and inserted into the nozzle cap to deliver the gas to the mixing space, A nozzle unit characterized in that the space between the first conduit and the second conduit formed by combining each other is in fluid communication with the mixing space.

2. In paragraph 1, A nozzle unit characterized in that the outer diameter of the second conduit is 5 mm.

3. In paragraph 2, The above nozzle, A first body having an insertion groove formed therein into which the first conduit is inserted; and A nozzle unit characterized by including a second body formed to protrude from the lower side of the first body and having a discharge hole formed in fluid communication with the insertion groove.

4. In paragraph 3, The above second conduit is combined with the above first body to form a space through which the gas flows, A nozzle unit characterized in that the above interspace, the separation space and the mixing space are in fluid communication with each other.

5. In paragraph 4, In the above second body, A nozzle unit characterized in that a gas guide groove is formed to guide the flow direction of the gas flowing from the above separation space to the above mixing space.

6. In paragraph 5, A nozzle unit characterized in that the above gas guide groove is formed in a vertical direction when viewed from the front.

7. In paragraph 5, A nozzle unit characterized in that the above gas guide groove is arranged in a diagonal direction when viewed from the front.

8. In paragraph 4, A nozzle unit characterized in that the above-mentioned separation space has an arcuate shape when viewed from above.

9. In paragraph 4, A nozzle unit characterized in that the above-mentioned separation space has a square shape when viewed from above.

10. In paragraph 1. The above injection hole is, A plurality of nozzle caps are formed along the circumference of the nozzle cap at the bottom of the nozzle cap, A nozzle unit characterized in that it is formed to slope in a direction toward the outside of the nozzle cap from the top of the injection hole to the bottom of the injection hole.

11. In paragraph 1, The above nozzle unit is used for intraperitoneal anticancer chemotherapy, The above drug is an anticancer drug, A nozzle unit characterized in that the gas is air or carbon dioxide.

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