Targeted drug-based quantitative drug delivery apparatus

By designing a quantitative drug delivery device with delivery, adjustment, and actuation components, the problem of inaccurate drug administration caused by the need for manual piston actuation in existing technologies has been solved. This enables precise delivery of targeted drugs in home care, reducing drug waste and improving drug safety.

WO2026064888A1PCT designated stage Publication Date: 2026-04-02HEBEI CHEM & PHARMA COLLEGE
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Patent Information

Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
Filing Date
2024-09-24
Publication Date
2026-04-02

AI Technical Summary

Technical Problem

Existing drug delivery devices require manual pushing of a sealed piston when administering medication through the nasal cavity, relying on the experience of medical staff, which leads to inaccurate dosage and makes it difficult to achieve precise drug delivery in home care.

Method used

A quantitative drug delivery device is designed, comprising a delivery component, an adjustment component, and a pushing component. The delivery component delivers the drug solution, the adjustment component adjusts the volume of the storage shell, and the pushing component squeezes the drug solution to achieve precise control of the dosage per dose.

Benefits of technology

This enables precise administration of targeted drugs in home care, reducing drug waste and improving the accuracy and safety of medication.

✦ Generated by Eureka AI based on patent content.

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Abstract

A targeted drug-based quantitative drug delivery apparatus, comprising a storage bottle (1). The top of the storage bottle (1) is communicated with a liquid injection tube (2). The bottom of the storage bottle (1) is provided with a delivery tube (3). One end of the delivery tube (3) is communicated with a spray head (4). A delivery assembly is provided inside the storage bottle (1). The delivery assembly comprises a movable slot (5). The movable slot (5) is provided inside the storage bottle (1). A storage housing (6) is provided inside the movable slot (5). One end of the storage housing (6) is communicated with a corrugated tube (7).
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Description

A targeted drug-based dosing device TECHNICAL FIELD

[0001] The present application belongs to the technical field of medical devices, and particularly relates to a targeted drug-based dosing device. BACKGROUND

[0002] The blood-brain barrier is a natural barrier between the systemic circulation and the central nervous system, which plays a barrier role to block pathogenic microorganisms and harmful substances from entering the brain. At the same time, it also hinders many drugs from entering the central nervous system through blood circulation to play a therapeutic role. Many current drug delivery methods, such as intracranial injection in situ, subarachnoid injection, and the like, and the current nasal drug delivery device are increasingly mature in terms of drug dispersion, transmission and distribution. From simple nasal cavity cleaning sprayer, nasal spray, to the application of ultrasonic atomization and osmotic pump in the nasal drug delivery device.

[0003] In the prior art, a targeted drug-based dosing device is disclosed in Chinese Patent No. CN219440377U. By setting a medicine storage barrel, a moving plate and a rubber cylinder, one end of the rubber cylinder is inserted into the nasal cavity, the push rod is pushed, the moving plate can move inside the medicine storage cylinder, so that the targeted drug inside the medicine storage cylinder is pushed out through the dosing channel, and at the same time, the moving plate extracts air at the bottom of the medicine storage cylinder, so that the refluxed drug in the nasal cavity enters the inside of the main body through the first recovery channel. The problem that the current drug delivery device does not have a reflux prevention part, directly communicates with the outside world, increases the possibility of drug contamination and deterioration, reduces the effective period of use of the drug, and the drug reflux easily leaks out, resulting in inaccurate drug delivery amount is solved.

[0004] However, the above-mentioned device still has the following problems in the implementation process: when the patient's nasal cavity is dosed, the sealing piston needs to be manually pushed to move, and the single injection amount is manually adjusted by observing the shell scale, which requires higher operation experience of medical personnel. In home nursing, nursing staff cannot master the injection amount of the drug in a short time, and single injection of too much drug often occurs, which not only causes waste of the drug, but also is not conducive to the recovery of the patient.

[0005] Therefore, we provide a targeted drug-based dosing device to solve the above-mentioned problems.

[0006] SUMMARY

[0007] The present application aims to provide a targeted drug-based dosing device, which solves the problem that the existing drug delivery device lacks an adjustment function and the drug delivery amount is not accurate by the cooperation of the delivery assembly, the adjustment assembly and the pushing assembly.

[0008] To solve the above technical problems, the present application is realized by the following technical solutions:

[0009] The present application is a kind of dosing device based on targeted drug, including storage bottle, the top of the storage bottle is communicated with liquid injection pipe, the bottom of the storage bottle is provided with delivery pipe, one end of the delivery pipe is communicated with spray head;

[0010] The inside of the storage bottle is provided with a delivery assembly, the delivery assembly includes a movable slot, the movable slot is opened in the inside of the storage bottle, the inside of the movable slot is provided with a storage shell, one end of the storage shell is communicated with a bellows, the surface of the bellows is sleeved with a first one-way valve, the surface of the delivery pipe is sleeved with a second one-way valve, the liquid medicine is delivered by the delivery assembly;

[0011] One side of the storage shell is provided with an adjusting assembly, the adjusting assembly includes a threaded pipe, the threaded pipe is movably connected to one side of the storage shell, a threaded rod is screwedly connected in the inside of the threaded pipe, the volume of the inside of the storage shell is adjusted by the adjusting assembly;

[0012] One side of the storage bottle is provided with a pushing assembly, the pushing assembly includes a movable plate, the movable plate is arranged on one side of the storage bottle, a sliding slot is opened in the inside of the movable plate, a movable shaft is slidably connected in the inside of the sliding slot, the liquid medicine is pressurized by the pushing assembly.

[0013] The present application is further provided that the delivery assembly further includes a sealing plug, the sealing plug is slidably connected in the inside of the storage shell, a sliding rod is fixedly connected to one side of the sealing plug, the other end of the sliding rod penetrates to the outside of the storage bottle and is movably connected with the movable shaft.

[0014] The present application is further provided that the surface of the sliding rod and located on one side of the storage shell is fixedly connected with a push plate, the push plate is slidably connected with the inner wall of the movable slot.

[0015] The present application is further provided that the surface of the sliding rod is sleeved with a spring, one end of the spring is fixedly connected with the storage shell.

[0016] The present application is further provided that the other end of the threaded rod penetrates to the outside of the storage bottle and is fixedly connected with a knob, the surface of the knob is movably connected with the inner wall of the storage bottle through a bearing.

[0017] The present application is further provided that a heating wire is fixedly connected in the inside of the storage bottle, a temperature sensor is installed in the inside of the storage bottle, the other end of the bellows is communicated with the storage bottle, the top end of the delivery pipe is communicated with the storage shell.

[0018] The present application is further provided that the top of the storage bottle is communicated with an air inlet pipe, the surface of the air inlet pipe is sleeved with a one-way air valve.

[0019] The application is further provided with a sealing cap threaded on the surface of the liquid injection pipe, and a first scale is arranged on the front side of the storage bottle.

[0020] The application is further provided with a strap fixedly connected to the top of the storage bottle, a hanging ring fixedly connected to the top of the strap, a movable seat movably connected to the top of the movable plate, a handle fixedly connected to one side of the movable seat, and the handle is fixedly connected to the storage bottle on one side.

[0021] The application is further provided with a pointer fixedly connected to the front side of the second one-way valve, a second scale arranged on the bottom of the storage bottle, and a horizontal groove formed in the bottom of the storage bottle.

[0022] The application has the following beneficial effects:

[0023] 1. The liquid medicine can be delivered to the storage bottle through the liquid injection pipe by the setting of the delivery assembly, and when the patient needs to be administered, the liquid medicine is delivered to the storage shell, the capacity of the storage shell corresponds to the second scale on the bottom of the storage bottle, the capacity of the storage shell can be set as the single injection amount, and the first one-way valve and the second one-way valve are used to deliver the liquid medicine to the spray head in one direction to accurately administer the patient.

[0024] 2. The position of the storage shell can be adjusted by rotating the threaded rod and moving the threaded pipe when the single dose of the patient needs to be adjusted, and when the storage shell moves to the right, the storage shell will be close to the sealing plug, at this time, the volume inside the storage shell will be reduced, which plays a role in adjusting the single injection amount.

[0025] 3. The patient can hold the storage bottle by the setting of the pushing assembly, and when the patient needs to be administered, the movable plate is manually pressed to move the movable shaft to adjust the position of the sealing plug, and when the sealing plug moves, the liquid medicine is extruded to be injected into the delivery pipe to realize the effect of spraying medicine.

[0026] Of course, any product implementing the present application does not necessarily need to achieve all the advantages described above. BRIEF DESCRIPTION OF DRAWINGS

[0027] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings needed for the embodiment description will be briefly introduced as follows.

[0028] Fig. 1 is a structure perspective view of a quantitative drug delivery device based on a targeted drug;

[0029] Fig. 2 is a sectional view of a storage bottle in a quantitative drug delivery device based on a targeted drug;

[0030] Figure 3 is a partial sectional view of a storage bottle and a storage shell in a targeted drug-based dosing device;

[0031] Figure 4 is a partial sectional view of a storage shell and a threaded tube in a targeted drug-based dosing device;

[0032] Figure 5 is a schematic view of the connection between a movable plate and a movable shaft in a targeted drug-based dosing device;

[0033] Figure 6 is a schematic view of the adjustment of a storage shell in a targeted drug-based dosing device;

[0034] Figure 7 is a schematic view of the bottom structure of a storage bottle in a targeted drug-based dosing device.

[0035] In the drawings: 1, storage bottle; 2, liquid injection tube; 3, delivery tube; 4, spray head; 5, movable groove; 6, storage shell; 7, bellows; 8, first one-way valve; 9, second one-way valve; 10, threaded tube; 11, threaded rod; 12, movable plate; 13, sliding groove; 14, movable shaft; 15, sealing plug; 16, sliding rod; 17, push plate; 18, spring; 19, knob; 20, heating wire; 21, temperature sensor; 22, air inlet tube; 23, sealing cap; 24, first scale; 25, bandage; 26, hanging ring; 27, movable seat; 28, handle; 29, pointer; 30, second scale; 31, transverse groove. DETAILED DESCRIPTION

[0036] The technical solutions in the embodiments of the present application will be described below with reference to the drawings in the embodiments of the present application. The described embodiments are only some of the embodiments of the present application, not all.

[0037] Embodiment One

[0038] Please refer to Figure 1-7, the present application is a kind of quantitative dosing device based on targeted drug, including storage bottle 1, the top of storage bottle 1 is communicated with liquid injection pipe 2, the bottom of storage bottle 1 is provided with delivery pipe 3, one end of delivery pipe 3 is communicated with spray head 4;Storage bottle 1 is provided with delivery assembly inside, delivery assembly includes movable slot 5, movable slot 5 is opened in the inside of storage bottle 1, movable slot 5 is provided with storage shell 6 inside, one end of storage shell 6 is communicated with bellows 7, first check valve 8 is sleeved on the surface of bellows 7, second check valve 9 is sleeved on the surface of delivery pipe 3, the liquid medicine is transported by delivery assembly;One side of storage shell 6 is provided with adjusting assembly, adjusting assembly includes threaded pipe 10, threaded pipe 10 is movably connected to one side of storage shell 6, threaded rod 11 is screw connected in the inside of threaded pipe 10, the volume inside storage shell 6 is adjusted by adjusting assembly;One side of storage bottle 1 is provided with pusher assembly, pusher assembly includes movable plate 12, movable plate 12 is arranged on one side of storage bottle 1, sliding slot 13 is opened in the inside of movable plate 12, movable shaft 14 is slidably connected in the inside of sliding slot 13, the liquid medicine is pressurized by pusher assembly.

[0039] Specifically: liquid injection pipe 2 is used to inject external medicine into storage bottle 1, a plurality of fine holes are opened in the inside of spray head 4, when the liquid medicine is injected into delivery pipe 3, the liquid medicine can be dispersed and sprayed out by using the pressure effect, uniform drug delivery is realized, the inner wall of storage shell 6 and movable slot 5 is slidably connected, the horizontal movement of storage shell 6 can be facilitated, bellows 7 has the function of expansion and contraction, can move with storage shell 6 and keep the communication between storage shell 6 and storage bottle 1, first check valve 8 is used to control the flow direction of bellows 7, so that the liquid medicine can only be injected from storage bottle 1 into storage shell 6.

[0040] Specific embodiment two

[0041] Please refer to Figure 1-7, on the basis of specific embodiment one, delivery assembly further includes sealing plug 15, sealing plug 15 is slidably connected in the inside of storage shell 6, one side of sealing plug 15 is fixedly connected with slide rod 16, the other end of slide rod 16 penetrates to the outside of storage bottle 1 and is movably connected with movable shaft 14, push plate 17 is fixedly connected on the surface of slide rod 16 and located on one side of storage shell 6, push plate 17 is slidably connected with the inner wall of movable slot 5, spring 18 is sleeved on the surface of slide rod 16, one end of spring 18 is fixedly connected with storage shell 6, the other end of threaded rod 11 penetrates to the outside of storage bottle 1 and is fixedly connected with knob 19, knob 19 is movably connected with the inner wall of storage bottle 1 through bearing on the surface, heating wire 20 is fixedly connected in the inside of storage bottle 1, temperature sensor 21 is installed in the inside of storage bottle 1, the other end of bellows 7 is communicated with storage bottle 1, the top end of delivery pipe 3 is communicated with storage shell 6.

[0042] Specifically, the second one-way valve 9 is used for controlling the opening and closing of the conveying pipe 3, so that the liquid medicine can only be conveyed from the storage shell 6 to the spray head 4; the movable shaft 14 is in sliding connection with the inner wall of the sliding groove 13, and can convert the circular motion into the horizontal motion of the sliding rod 16 when the movable plate 12 rotates around the movable shaft 14 as the axis, so that the motion interference does not occur; the surface of the sealing plug 15 is made of rubber material, and the sealing plug 15 can extrude and convey the liquid medicine when sliding in the storage shell 6.

[0043] Embodiment three

[0044] Referring to FIGS. 1-7, on the basis of the first embodiment, the storage bottle 1 is connected with an air inlet pipe 22 at the top, the surface of the air inlet pipe 22 is sleeved with a one-way air valve, the surface of the liquid injection pipe 2 is threadedly connected with a sealing cap 23, the front side of the storage bottle 1 is provided with a first scale 24, the top of the storage bottle 1 is fixedly connected with a bandage 25, the top of the bandage 25 is fixedly connected with a hanging ring 26, the top of the movable plate 12 is movably connected with a movable seat 27, one side of the movable seat 27 is fixedly connected with a handle 28, one side of the handle 28 is fixedly connected with the storage bottle 1, the front side of the second one-way valve 9 is fixedly connected with a pointer 29, the bottom of the storage bottle 1 is provided with a second scale 30, and the bottom of the storage bottle 1 is provided with a horizontal groove 31.

[0045] Specifically, the push plate 17 is fixed on the surface of the sliding rod 16 and can move with the sliding rod 16; the springs 18 can elastically support the push plate 17 by compression energy storage; the knob 19 is used for driving the threaded rod 11 to rotate; the heating wire 20 can preheat the inside of the storage bottle 1, so that the temperature of the liquid medicine is maintained at a suitable temperature of the human body, thereby reducing the stimulation of the patient when taking medicine in cold weather; the temperature sensor 21 can detect the temperature of the liquid medicine; the one-way air valve can control the opening and closing of the air inlet pipe 22, so that the external gas can enter the inside of the storage bottle 1; the pointer 29 is fixed on the front side of the second one-way valve 9 and can move with the conveying pipe 3; the second scale 30 is the same as the capacity inside the storage shell 6, so that the medical staff can conveniently observe the capacity inside the storage shell 6; the conveying pipe 3 is in sliding connection with the inner wall of the horizontal groove 31, and can limit the rotation of the threaded pipe 10.

[0046] The working principle of the application is as follows: when it is necessary to take medicine for the patient, the medical staff or the patient himself holds the storage bottle 1, observes the second scale 30 at the bottom of the storage bottle 1, and observes the capacity inside the storage shell 6; the capacity inside the storage shell 6 is the capacity of single injection;

[0047] When it is necessary to adjust the single injection amount, the medical staff manually rotates the knob 19, the knob 19 cooperates with the threaded rod 11 to drive the threaded pipe 10 to move, the threaded pipe 10 pushes the storage shell 6, and the storage shell 6 moves and approaches the sealing plug 15; at this time, the volume inside the storage shell 6 is reduced, thereby achieving the effect of adjusting the single injection amount.

[0048] Then the mobile storage bottle 1 inserts the spray head 4 into the patient's nostril, and manually presses the movable plate 12, so that the movable plate 12 rotates around the shaft of the movable seat 27, and the movable shaft 14 is pushed, the movable shaft 14 drives the sealing plug 15 to move through the sliding rod 16, when the sealing plug 15 moves, the air in the storage shell 6 is extruded, and is discharged through the second one-way valve 9 and the delivery pipe 3, the sliding rod 16 is extruded while cooperating with the push plate 17 to extrude the spring 18;

[0049] Then release the movable plate 12, at this time the spring 18 cooperates with the push plate 17 to reset the sliding rod 16, the sliding rod 16 drives the sealing plug 15 to move, the sealing plug 15 extracts the air in the storage bottle 1, at this time the first one-way valve 8 will be opened, the liquid medicine in the storage bottle 1 is injected into the storage shell 6 through the bellows 7, the capacity in the storage shell 6 is the capacity of single injection, then press the movable plate 12 again, the sealing plug 15 is extruded through the movable plate 12, at this time the liquid medicine will enter the spray head 4 through the delivery pipe 3, and the liquid medicine is sprayed out through the spray head 4, and the patient is accurately medicated.

[0050] The standard parts used in the application can be purchased from the market, and can be ordered according to the description and drawings. The specific connection mode of each part adopts the conventional means such as bolt, rivet and welding in the prior art. The mechanical parts and equipment adopt the conventional type in the prior art. The control mode is automatically controlled through the control unit. The control circuit of the control unit can be realized by simple programming of the person skilled in the art, which belongs to the public knowledge in the art. Therefore, the control mode and circuit connection in the application are not explained in detail.

[0051] The preferred embodiments of the application disclosed above are only used to help explain the application. The preferred embodiments do not describe all the details, and the application is not limited to the specific embodiments described. The embodiments are selected and described in the specification in order to better explain the principles and practical applications of the application, so that the person skilled in the art can well understand and utilize the application.

Claims

1. A target drug-based dosing device comprising a storage bottle (1), characterized in that: The top of the storage bottle (1) is communicated with a liquid injection pipe (2), and the bottom of the storage bottle (1) is provided with a delivery pipe (3), one end of the delivery pipe (3) is communicated with a spray head (4); The inside of the storage bottle (1) is provided with a delivery assembly, the delivery assembly comprises a movable groove (5), the movable groove (5) is arranged in the inside of the storage bottle (1), the inside of the movable groove (5) is provided with a storage shell (6), one end of the storage shell (6) is communicated with a bellows (7), the surface of the bellows (7) is sleeved with a first one-way valve (8), the surface of the delivery pipe (3) is sleeved with a second one-way valve (9), and the liquid medicine is delivered through the delivery assembly; One side of the storage shell (6) is provided with an adjusting assembly, the adjusting assembly comprises a threaded pipe (10), the threaded pipe (10) is movably connected to one side of the storage shell (6), and the inside of the threaded pipe (10) is threadedly connected with a threaded rod (11), the volume of the inside of the storage shell (6) is adjusted through the adjusting assembly; One side of the storage bottle (1) is provided with a pushing assembly, the pushing assembly comprises a movable plate (12), the movable plate (12) is arranged on one side of the storage bottle (1), the inside of the movable plate (12) is provided with a sliding groove (13), the inside of the sliding groove (13) is slidably connected with a movable shaft (14), and the liquid medicine is pressurized through the pushing assembly.

2. A target drug-based dosing device according to claim 1, characterized in that: The delivery assembly further comprises a sealing plug (15), the sealing plug (15) is slidably connected in the inside of the storage shell (6), one side of the sealing plug (15) is fixedly connected with a sliding rod (16), and the other end of the sliding rod (16) penetrates to the outside of the storage bottle (1) and is movably connected with the movable shaft (14).

3. A target drug-based dosing device according to claim 2, characterized in that: The surface of the sliding rod (16) and located on one side of the storage shell (6) is fixedly connected with a push plate (17), and the push plate (17) is slidably connected with the inner wall of the movable groove (5).

4. A target drug-based dosing device according to claim 3, characterized in that: The surface of the sliding rod (16) is sleeved with a spring (18), one end of the spring (18) is fixedly connected with the storage shell (6).

5. The targeted drug-based dosing device of claim 1, wherein: The other end of the threaded rod (11) penetrates to the outside of the storage bottle (1) and is fixedly connected with a knob (19), and the surface of the knob (19) is movably connected with the inner wall of the storage bottle (1) through a bearing.

6. A targeted drug-based dosing device according to claim 1, characterized in that: The inside of the storage bottle (1) is fixedly connected with a heating wire (20), the inside of the storage bottle (1) is provided with a temperature sensor (21), the other end of the bellows (7) is communicated with the storage bottle (1), and the top end of the delivery pipe (3) is communicated with the storage shell (6).

7. The targeted drug-based dosing device of claim 1, wherein: The top of the storage bottle (1) is communicated with an air inlet pipe (22), and the surface of the air inlet pipe (22) is sleeved with a one-way air valve.

8. A targeted drug-based dosing device according to claim 1, characterized in that: The surface of the liquid injection pipe (2) is threadedly connected with a sealing cap (23), and the front side of the storage bottle (1) is provided with a first scale (24).

9. A targeted drug-based dosing device according to claim 1, characterized in that: The top of the storage bottle (1) is fixedly connected with a bandage (25), the top of the bandage (25) is fixedly connected with a hanging ring (26), the top of the movable plate (12) is movably connected with a movable seat (27), one side of the movable seat (27) is fixedly connected with a handle (28), and one side of the handle (28) is fixedly connected with the storage bottle (1).

10. The targeted drug-based dosing device of claim 1, wherein: The second one-way valve (9) is fixedly connected with a pointer (29) in front side, the bottom of the storage bottle (1) is provided with a second scale (30), and the bottom of the storage bottle (1) is provided with a horizontal groove (31).

Citation Information

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