Insecticidal composition containing oxazosulfyl and use thereof

Abstract

An insecticidal composition containing oxazosulfyl and a use thereof, relating to the technical field of pesticides. The insecticidal composition comprises an active ingredient A and an active ingredient B, wherein the active ingredient A is oxazosulfyl; and the active ingredient B is selected from one or more of the following compounds: an acetylcholinesterase inhibitor, a nicotinic acetylcholine receptor (nAChR) channel blocker, an nAChR allosteric modulator site I, an nAChR competitive modulator, a glutamate-gated chloride channel (GluCl) allosteric modulator, etc. The composition has a reasonable formulation, good insecticidal efficacy, and low application costs, and has the characteristics of reduced application amount, safety to crops, reduced pesticide residue, etc.

Description

An insecticidal composition comprising oxazolidinyl acetamiprid and its application Technical Field

[0001] This invention belongs to the field of pesticide technology, specifically relating to an insecticidal composition containing oxazolidinyl sulfadiazine and its application. Background Technology

[0002] In agricultural production, the control of various harmful insects mainly relies on the application of large quantities of pesticides. The excessive, frequent, and irrational use of pesticides leads to increasing resistance in harmful insects, resulting in more severe damage to crops and making control increasingly difficult. Combining two or more pesticides with different mechanisms of action can achieve simultaneous control of different pests, improve pesticide efficacy, and reduce the development of pesticide resistance. Summary of the Invention

[0003] This invention provides an insecticidal composition containing oxazolidinyl acetamiprid and its application. The composition has a reasonable composition, good insecticidal effect, low application cost, and features reduced application amount, crop safety, and reduced pesticide residues.

[0004] An insecticidal composition comprising oxazolidinone, comprising active ingredient A and active ingredient B, wherein active ingredient A is oxazolidinone (CAS No.: 21616678-32-0); and active ingredient B is selected from one or more of the following compounds:

[0005] (1) Acetylcholinesterase inhibitors: acephate (CAS No.: 30560-19-1), phoxim (CAS No.: 14816-18-3), carbofuran (CAS No.: 55285-14-8), chlorpyrifos (CAS No.: 2921-88-2), malathion (CAS No.: 121-75-5);

[0006] (2) Nicotinic acetylcholine receptor (nAChR) channel blocker: Insecticide (CAS No.: 29547-00-0);

[0007] (3) Nicotinic acetylcholine receptor (nAChR) allosteric regulator site I: spinosad (CAS No.: 168316-95-8), ethyl spinosad (CAS No.: 935545-74-7);

[0008] (4) Competitive regulators of nicotinic acetylcholine receptors (nAChR): thiamethoxam (CAS No.: 111988-49-9), acetamiprid (CAS No.: 135410-20-7), (CN202411698302.0);

[0009] (5) Allosteric regulators of glutamate-gated chloride channels (GluCl): avermectin benzoate (CAS No.: 155569-91-8), avermectin (CAS No.: 71751-41-2);

[0010] (6) Inhibitors of chitin biosynthesis that affect CHS1: Lufenuron (CAS No.: 103055-07-8), Flufenoxuron (CAS No.: 71422-67-8);

[0011] (7) Chitin biosynthesis inhibitor: Thiazidinone (CAS No.: 953030-84-7);

[0012] (8) Ecdysone receptor agonist: methoxyfenozide (CAS No.: 161050-58-4);

[0013] (9) Voltage-dependent sodium ion channel blocker: indoxacarb (CAS No.: 173584-44-6);

[0014] (10) Rhododendron receptor modulators: bromocyanamide (CAS No.: 736994-63-1), tetrachlorantraniliprole (CAS No.: 1104384-14-6), tetrazolium amide (CAS No.: 1229654-66-3);

[0015] (11) GABA-gated chloride channel allosteric modulators: brofenoxam (CAS No.: 1207727-04-5), isoxaflutole (CAS No.: 2061933-85-3), Oxadiazon;

[0016] (12) Sodium ion channel modulators: Ethylhexyl (CAS No.: 80844-07-1), deltamethrin (CAS No.: 52918-63-5), cypermethrin (CAS No.: 51630-58-1), bifenthrin (CAS No.: 82657-04-3);

[0017] (13) Acetyl-CoA carboxylase inhibitor: Biscayne (CAS No.: 907187-07-9);

[0018] (14) Nicotinamide inhibitors for string instruments: flunitrazepam (CAS No.: 158062-67-0), trifluoromethylnicotinamide (CAS No.: 158062-71-6);

[0019] (15) String instrument TRPV channel modifier: Indoxoril (CAS No.: 1689545-27-4) (CN202411096509.0);

[0020] (16) Inhibitor of mitochondrial electron transport complex (I): Pyridaben (CAS No.: 96489-71-3);

[0021] (17) Others: (CN202410765633.5) (CN202411578205.8).

[0022] In one specific implementation, the weight ratio of A and B is 200:1-1:300, 100:1-1:200, 50:1-1:100, 40:1-1:50, 20:1-1:20, 10:1-1:10, 8:1-1:5, 5:1-1:2, or 2:1-1:1.

[0023] The present invention also discloses the application of the insecticidal composition in the control of plant pests in agriculture, forestry and horticulture.

[0024] The present invention also provides the use of the insecticidal composition for preventing or controlling harmful organisms that invade crops or crop propagation material.

[0025] The present invention also provides a method for preventing or controlling pests, which involves applying the insecticidal composition to a target pest and / or its environment.

[0026] The present invention also provides a method for preventing or controlling pests, which involves applying the insecticidal composition to seeds, a target crop, or soil in which the target crop grows or soil suitable for the growth of the target crop.

[0027] The present invention also provides a method for protecting a target crop from pest infestation, which involves contacting the insecticidal composition described herein with the target crop, the target pest and / or its environment, and the reproductive material of the target crop.

[0028] According to one aspect of the invention, the composition can be used not only for lepidopteran, hemiptera, and coleopteran pests, but also for the control of a wide range of agricultural and horticultural pests (e.g., insects such as tsioptera and diptera, or nematodes, harmful mites, etc.). It is particularly preferred for lepidopteran, hemiptera, and coleopteran pests, as exemplified by the following examples.

[0029] Lepidoptera pests: Wood-boring moth (Cossus insularis), tea leaf roller (Adoxophyes honmai), apple leaf roller (Adoxophyes orana faciata), pear fruit moth (Grapholita molesta), tea long leaf roller (Homona magnamina), soybean fruit moth (Leguminivora glycinivorella), silver-striped leaf miner (Lyonetia prunifoliella malinella), tea leafminer (Caloptilia theivora), golden-striped leafminer (Phyllonorycter ringoniella), citrus leafminer (Phyllocnistis citrella), onion moth (Acrolepiopsis sapporensis), diamondback moth (Plutella xylostella), apple silver moth (Argyresthia conjugella), grape clearwing moth (Nokona regalis), apple clearwing moth (Synanthedon hector), persimmon leafminer (Stathmopoda) The following species are listed: masinissa, peach fruit moth (Carposina sasakii), yellow tussock moth (Monema flavescens), rice stem borer (Chilo suppressalis), rice leaf roller (Cnaphalocrocis medinalis), Chinese cabbage moth (Hellila undalis), Asian corn borer (Ostrinia furnacalis), annual bluegrass stem borer (Parapediasia teterrella), Mediterranean leaf roller (Ephestia kuehniella), large wax moth (Galleris mellonella), yellow swallowtail butterfly (Papilio machaon hippocrates), white-white butterfly (Pieris rapae crucivora), straight-striped rice skipper (Parnara guttata), large bridge-building insect (Ascotis selenaria), sweet potato hawk moth (Agrius convolvuli), tussock moth (Orgyia thyellina), fall webworm (Hyphantria cunea), small cutworm (Agrotis). ipsilon, yellow cutworm (Agrotis segetum), bean silver-striped noctuid moth (Autographa nigrisigna), powdery noctuid moth (Trichoplusia ni), cotton bollworm (Helicoverpa)The following are listed as examples of leafminer moths: *Helicoverpa assulta*, *Mamestra brassicae*, *Mythimna separata*, *Naranga aenescens*, *Spodoptera exigua*, *Spodoptera litura*, *Helicoverpa zea*, *Heliothis virescens*, *Spodoptera littoralis*, *Spodoptera frugiperda*, *Spodoptera eridania*, *Manduca sexta*, *Endopiza viteana*, *Pectinophora gossypiella*, *Cydla pomonella*, *Ostrinia nubilalis*, and *Pseudoplusia includens*.

[0030] Coleoptera pests: Rice weevil (Sitophilus oryzaelinne), corn weevil (S. zeamails), grain weevil (S. granarius), large ape leaf beetle (Cabbageleaf beetle), small ape leaf beetle (Daikon leaf beele), flea beetle (flea beetle), grape flea beetle (Altica chalybea), yellow striped flea beetle (phyllotretastriolata), cucumber flea beetle (Epitrix cucumeris), tobacco flea beetle (Ehirtipennis), eggplant flea beetle (E. fuscula), cucumber beetle (Aula cophora ndica (Gemlin), mustard leaf beetle (Phaedon cochleariae), etc.

[0031] Homoptera pests: *Acyrthosiphon pisum Harris* (bean aphid), *Aphis craccivora Koch* (black bean aphid), *Aphis fabae Scopoli* (broad bean aphid), *Aphis gossypii Glover* (cotton aphid, melon aphid), *Aphis pomi De Geer* (apple aphid), *Aphis spiraecola Patch* (leaf-rolling aphid), *Aulacorthum solani Kaltenbach* (eggplant aphid), *Chaetosiphon fragaefolii Cockerell* (strawberry aphid), *Diuraphis noxia Kurdjumov / Mordvilko* (Russian wheat aphid), *Dysaphis plantaginea Paaserini* (red apple aphid), *Eriosoma lanigerum Hausmann* (cotton apple aphid), *Hyalopterus pruni Geoffroy* (peach aphid), *Lipaphis erysimi Kaltenbach* (radish aphid), *Metopolophium dirhodum Walker* (wheat aphid), *Macrosiphum euphorbiae* Thomas (potato aphid), Myzus persicae Sulzer (peach aphid), Nasonovia ribisnigri Mosley (lettuce aphid), Pemphigus (root aphids and hummus aphids), Rhopalosiphum maidis Fitch (corn leaf aphid), Rhopalosiphum padi Linnaeus (grain overflow aphid), Schizaphis graminum Rondani (wheat two-forked aphid), Sitobion avenae Fabricius (wheat long-tubed aphid), Therioaphis maculata Buckton (alfalfa spotted aphid), Toxoptera aurantii Boyer de Fonscolombe (orange two-forked aphid) and Toxoptera citricida Kirkaldy (brown orange aphid); Adelges (ball aphid); Phylloxera devastatrix Pergande (American pecan root phylloxera);Bemisia tabaci Gennadius (sweet potato whitefly), Bemisia argentifolii Bellows & Perring (silver leaf whitefly), Dialeurodes citri Ashmead (citrus whitefly), and Trialeurodes vaporariorum Westwood (greenhouse whitefly); Empoasca fabae Harris (potato leafhopper), Laodelphax striatellus Fallen (gray leafhopper), Macrosteles quadrilineatus Forbes (two-spotted leafhopper), Nephotettix cincticeps Uhler (green leafhopper), and Nephotettix nigropictus; (Black-tailed Leafhopper), Nilaparvata lugens (Brown planthopper), Peregrinus maidis Ashmead (corn planthopper), Sogatella furcifera Horvath (white-backed planthopper), Sogatodes orizicola Muir (rice planthopper), Typhlocyba pomaria McAtee, white apple leafhopper, Erythroneura (grape leafhopper); Magicicada septendecim Linnaeus (periodic cicada); Icerya purchasi Maskell (cotyledonous scale insect), Quadraspidiotus perniciosus Comstock (Saint Joseph's insect); Planococcus citri Risso (citrus mealybug); Pseudococcus (other mealybug complexes); Cacopsylla pyricola Foerster (pear psyllid), Trioza diospyri Ashmead (persimmon psyllid).

[0032] The active ingredients of the compositions of the present invention can be prepared by disclosed methods or by purchasing commercially available formulations. These compounds, combined with surfactants and necessary adjuvants in appropriate proportions, are dissolved, separated, suspended, mixed, impregnated, adsorbed, or attached to a suitable inert carrier to prepare various dosage forms, such as aqueous suspensions, emulsion suspensions, emulsions, liquids, wettable powders, wettable granules, granules, powders, microcapsules, capsules, tablets, large granules, or sachets, before use.

[0033] The insecticidal composition comprises A and B in a mass percentage of 1-95% of the total, preferably 5-80%. Typically, the insecticidal composition of the present invention contains 1-95 parts by weight of the active ingredient and 5-99 parts by weight of conventional pesticide adjuvants.

[0034] These active ingredients can be used directly in commercially available formulations, or they can be formulated individually or together. During formulation, the active ingredients are dissolved, separated, suspended, mixed, impregnated, adsorbed, or attached to a suitable inert carrier. Alternatively, as needed, the active ingredients and excipients can be combined in appropriate proportions and then dissolved, separated, suspended, mixed, impregnated, adsorbed, or attached to a suitable inert carrier to create appropriate dosage forms, such as suspensions (flowing agents), emulsion suspensions, emulsions, liquids, wettable powders, wettable granules, granules, powders, microcapsules, capsules, tablets, large granules, or sachets.

[0035] As inert carriers, examples include solid and liquid carriers. Solid carriers include, for example, natural minerals such as quartz, clay, kaolin, pyrophyllite, sericite, talc, bentonite, acid clay, magnesia, zeolite, and diatomaceous earth; inorganic salts such as calcium carbonate, ammonium sulfate, sodium sulfate, and potassium chloride; organic solid carriers such as synthetic silicic acid, synthetic silicates, starch, cellulose, and plant powders (e.g., sawdust, coconut shells, corncobs, tobacco stalks); plastic carriers such as polyethylene, polypropylene, and polyvinylidene chloride; urea; inorganic hollow materials; plastic hollow materials; and fumed silica (white carbon black). These can be used individually or in combination of two or more. Examples of liquid carriers include monohydric alcohols such as methanol, ethanol, propanol, isopropanol, and butanol; polyhydric alcohols such as ethylene glycol, diethylene glycol, propylene glycol, hexanediol, polyethylene glycol, polypropylene glycol, and glycerol; polyhydric alcohol compounds such as propylene glycol ethers; ketones such as acetone, methyl ethyl ketone, methyl isobutyl ketone, diisobutyl ketone, and cyclohexanone; ethers such as diethyl ether, dioxane, ethylene glycol monoethyl ether, dipropyl ether, and tetrahydrofuran; aliphatic hydrocarbons such as n-alkanes, cycloalkanes, isoalkanes, kerosene, and mineral oil; and benzene, toluene, and xylene. The following are solvents: aromatic hydrocarbons such as naphtha and alkylnaphthalene; halogenated hydrocarbons such as dichloromethane, chloroform, and carbon tetrachloride; esters such as ethyl acetate, diisopropyl phthalate, dibutyl phthalate, dioctyl phthalate, and dimethyl adipate; lactones such as γ-butyrolactone; amides such as dimethylformamide, diethylformamide, dimethylacetamide, and N-alkylpyrrolidone (N-methylpyrrolidone, etc.); nitriles such as acetonitrile; sulfur compounds such as dimethyl sulfoxide; vegetable oils such as soybean oil, rapeseed oil, cottonseed oil, and castor oil; and water. These can be used alone or in combination of two or more.

[0036] Examples of additives include surfactants, binders, thickeners, colorants, antifreeze agents, anti-caking agents, disintegrants, and decomposition inhibitors, which can be used as dispersants, wetting agents, spreaders, or stretching agents. In addition, preservatives and plant extracts can be added as needed. These additives can be used alone or in combination of two or more.

[0037] Surfactants used as dispersants / wetting agents / spreaders / expanding agents, etc., include, for example: sorbitan fatty acid esters, polyoxyethylene sorbitan fatty acid esters, sucrose fatty acid esters, polyoxyethylene fatty acid esters, polyoxyethylene resin esters, polyoxyethylene fatty acid diesters, polyoxyethylene alkyl ethers, polyoxyethylene alkyl aryl ethers, polyoxyethylene alkylphenyl ethers, polyoxyethylene dialkylphenyl ethers, polyoxyethylene alkylphenyl ether formalin condensates, polyoxyethylene polyoxypropylene block copolymers, polystyrene polyoxyethylene block polymers, alkyl polyoxyethylene polypropylene block copolymer ethers, polyoxyethylene alkylamines, polyoxyethylene fatty acid amides, polyoxyethylene fatty acid diphenyl ethers, polyalkylene benzylphenyl ethers, polyoxyethylene styrene phenyl ethers, acetylene glycol, polyoxyethylene addition acetylene glycol, polyoxyethylene ether-type polysiloxanes, ester-type polysiloxanes, fluorinated surfactants, and polyoxyethylene castor oil. Nonionic surfactants such as polyoxyethylene-cured castor oil; cationic surfactants such as alkyl sulfates, polyoxyethylene alkyl ether sulfates, polyoxyethylene alkylphenyl ether sulfates, polyoxyethylene styrene phenyl ether sulfates, alkylbenzene sulfonates, alkylaryl sulfonates, lignin sulfonates, alkyl sulfosuccinates, naphthalene sulfonates, alkyl naphthalene sulfonates, formalin condensate salts of naphthalene sulfonic acid, formalin condensate salts of alkyl naphthalene sulfonic acid, fatty acid salts, polycarboxylate salts, polyacrylates, N-methyl-fatty acid sarcosine esters, resin salts, polyoxyethylene alkyl ether phosphates, and polyoxyethylene alkylphenyl ether phosphates; cationic surfactants such as alkylamine salts such as dodecylamine hydrochloride, stearamine hydrochloride, oleylamine hydrochloride, stearamine acetate, octadecylaminopropylamine acetate, alkyltrimethylammonium chloride, and alkyldimethylbenzalkonium chloride; and amphoteric surfactants such as amino acid-type or betaine-type surfactants. These surfactants can be used alone or in combination of two or more.

[0038] Examples of adhesives or tackifiers include carboxymethyl cellulose and its salts, dextrin, water-soluble starch, xanthan gum, guar gum, sucrose, polyvinylpyrrolidone, gum arabic, polyvinyl alcohol, polyvinyl acetate, sodium polyacrylate, polyethylene glycol with an average molecular weight of 6,000 to 20,000, polyethylene oxide with an average molecular weight of 100,000 to 5,000,000, phospholipids (e.g., cephalin, lecithin), cellulose powder, dextrin, processed starch, polyaminocarboxylic acid chelates, cross-linked polyvinylpyrrolidone, copolymers of maleic acid and styrene, (meth)acrylic acid copolymers, half-esters of polymers formed from polyols and dianhydrides, water-soluble salts of polystyrene sulfonic acid, paraffin wax, terpenes, polyamide resins, polyacrylates, polyoxyethylene, waxes, polyvinyl alkyl ethers, alkylphenol formalin condensates, and synthetic resin emulsions.

[0039] Examples of thickeners include water-soluble polymers such as xanthan gum, guar gum, diter gum, carboxymethyl cellulose, polyvinylpyrrolidone, carboxyethylene polymers, acrylic polymers, starch derivatives, and polysaccharides; and inorganic micro-powders such as high-purity bentonite and fumed silica (white carbon black).

[0040] Examples of coloring agents include inorganic pigments such as iron oxide, titanium oxide, and Prussian blue; and organic dyes such as alizarin dyes, azo dyes, and metallic phthalocyanine dyes.

[0041] Examples of antifreeze agents include polyols such as ethylene glycol, diethylene glycol, propylene glycol, and glycerol.

[0042] Examples of additives used to prevent caking or promote disintegration include starch, alginate, mannose, galactose and other polysaccharides, polyvinylpyrrolidone, fumed silica (white carbon black), ester gums, petroleum resins, sodium tripolyphosphate, sodium hexametaphosphate, metal stearate, cellulose powder, dextrin, copolymers of methacrylates, polyvinylpyrrolidone, polyaminocarboxylic acid chelates, sulfonated styrene-isobutylene-maleic anhydride copolymers, and starch-polyacrylonitrile graft copolymers.

[0043] Examples of decomposition inhibitors include zeolite, quicklime, and magnesium oxide; antioxidants such as phenolic compounds, amine compounds, sulfur compounds, and phosphoric acid compounds; and ultraviolet absorbers such as salicylic acid compounds and benzophenone compounds. Examples of preservatives include potassium sorbate and 1,2-benzothiazolin-3-one.

[0044] In addition, depending on the needs, other additives such as functional spreading agents, metabolic decomposition inhibitors such as piperonyl butyl ether, antioxidants such as BHT, and ultraviolet absorbers can also be used.

[0045] The term "crop" to which the insecticidal composition of the present invention can be used is not particularly limited, but also includes: genetically recombinant crops that have been endowed with useful traits through classical breeding methods or recent advancements in gene recombination technology (herbicide-resistant crops, pest-resistant crops with genes that have been integrated to produce insecticidal proteins, disease-resistant crops with genes that have been integrated to induce resistance to diseases, crops with improved taste, crops with improved shelf life, crops with increased yield, etc.).

[0046] In the use of the insecticidal composition of the present invention, the above-mentioned pre-contained formulation, which is effective in controlling various pests, is applied directly to the pests, or to the target crop for which the occurrence of the pest is predicted, or to the seeds, soil or cultivation carrier used for sowing, in its original state or in a form appropriately diluted or suspended with water, through conventional treatment. Examples of treatment methods include: dispersing treatment to stems and leaves, rice seedling box treatment, seed treatment such as seed dressing / soaking / disinfection, planting hole treatment, root treatment, furrow treatment, irrigation treatment, soil mixing treatment, etc. Treatment of hydroponic solutions in hydroponic cultivation is also possible.

[0047] When using the insecticidal composition of the present invention, in order to control simultaneously occurring pests, diseases, and weeds, enhance the effect, and reduce crop damage, agricultural and horticultural fungicides, agricultural and horticultural insecticides, agricultural and horticultural herbicides, synergists, and safeners can be used simultaneously.

[0048] The beneficial effects of this invention are:

[0049] 1) The components of this invention are reasonable, the insecticidal effect is good, the cost of application is low, and its insecticidal activity is not a simple superposition of active ingredients, but has a significant synergistic effect. It can delay the development of pesticide resistance in target pests, is safe for crops, and meets the safety requirements of pesticide formulations.

[0050] 2) The composition of the present invention is safe for non-target organisms and natural enemies, and can effectively reduce the dosage of the agent and reduce the pesticide residue on agricultural products. Detailed Implementation

[0051] To make the objectives, technical solutions, and advantages of this invention clearer and more concise, the invention is described using the following specific embodiments, but the invention is by no means limited to these embodiments. The embodiments described below are merely preferred embodiments of the invention and can be used to describe the invention, but should not be construed as limiting the scope of the invention. It should be noted that any modifications, equivalent substitutions, and improvements made within the spirit and principles of this invention should be included within the protection scope of this invention.

[0052] Composition insecticide activity assay:

[0053] (1) Test conditions and operating procedures

[0054] The active ingredient is purchased from a reagent company or synthesized using conventional methods. After being diluted with acetone, it is further diluted with deionized water to create gradient concentrations.

[0055] Fall armyworm, armyworm, and striped flea beetle: Test insects with consistent physiological states, continuously reared indoors, were selected and placed into 9cm diameter plastic boxes, 10 insects per box. Host plant leaves were added to each box (corn leaves for fall armyworm and armyworm, and radish leaves for striped flea beetles). Two tablets of pesticide were placed in each box, and the insecticide was applied using a spray tower. After application, the box lid was tightly closed. This process was repeated three times. The highest dose containing acetone served as a control. After application, the insects were transferred to an insecticide-treated room for rearing. The number of dead insects was investigated after 48 hours, and the mortality rate for each treatment was calculated. Mortality rate = (number of dead insects / number of test insects) × 100%.

[0056] Brown planthoppers: Select brown planthoppers of uniform physiological condition kept indoors and place them in disposable transparent plastic cups. Introduce 30 planthoppers of uniform growth into each cup, and place rice stalks in the cups. Wrap the rice stalks with moist cotton balls to maintain humidity. Then, spray using a spray tower. After spraying, cover the cup openings. Repeat three times, using the highest dose of acetone as a control. After treatment, transfer the planthoppers to an insecticide-treated room. After 48 hours, investigate the number of dead planthoppers and calculate the mortality rate. Mortality rate = (number of dead planthoppers / number of planthoppers tested) × 100%.

[0057] Peach aphids: Radish plants were planted in disposable cups, 3-4 plants per cup. When the radish seedlings reached about 8cm in height, the aphids were inoculated. After 3-4 days, once the aphid population reached a certain size, an experiment was conducted. The active ingredient was dissolved in acetone and diluted with deionized water to create gradient concentrations. A small spray bottle was used for spraying, applying 10-12 sprays per cup, until both sides of the leaves were moist but not dripping. This was repeated 3 times, with the highest dose containing acetone serving as a control. After application, the plants were transferred to an insecticide treatment room for rearing. The number of dead aphids was assessed after 48 hours, and the mortality rate was calculated. Mortality rate = (number of dead aphids / number of tested aphids) × 100%.

[0058] Peanut aphids: Broad bean plants were planted in disposable cups, one plant per cup. When the seedlings reached approximately 10cm in height, the aphids were inoculated. After 3-4 days, once the aphid population reached a certain size, an experiment was conducted. The active ingredient was dissolved in acetone and diluted with deionized water to create gradient concentrations. A small spray bottle was used for spraying, applying 6-9 times per cup, until both sides of the leaves were moist but not dripping. This was repeated three times, with the highest dose containing acetone serving as a control. After application, the plants were transferred to an insecticide treatment room for rearing. The number of dead aphids was assessed after 48 hours, and the mortality rate was calculated. Mortality rate = (Number of dead aphids / Number of tested aphids) × 100%.

[0059] (2) Qualitative evaluation of efficiency improvement

[0060] Toxicity was determined by setting different ratios within the selected range, and the optimal ratio was selected based on the synergistic effect. A synergistic effect > 0 indicates a synergistic effect; a synergistic effect close to 0 indicates an additive effect; and a synergistic effect < 0 indicates an antagonistic effect. Synergistic effect = Actual mortality rate - Theoretical mortality rate. Theoretical mortality rate = 1 - (1 - P1)(1 - P2)

[0061] In the formula, P1 and P2 are the mortality rates of each individual dose in the mixture.

[0062] Table 1. Qualitative evaluation results of the composition synergistic effect

[0063] Although the present invention has been described in detail above with general descriptions and specific embodiments, some modifications or improvements can be made to it, which are obvious to those skilled in the art. Therefore, all such modifications or improvements made without departing from the spirit of the present invention are within the scope of protection claimed by the present invention.

Claims

1. An insecticidal composition comprising oxadiazon, characterized in that, The insecticidal composition comprises active ingredient A and active ingredient B, wherein active ingredient A is oxazolidinyl sulfadiazine; and active ingredient B is selected from one or more of the following compounds: (1) Acetylcholinesterase inhibitors: acephate, phoxim, carbofuran, chlorpyrifos, malathion; (2) Nicotinic acetylcholine receptor (nAChR) channel blockers: Insecticidal monoclonal antibody; (3) Nicotinic acetylcholine receptor (nAChR) allosteric regulator site I: spinosad, ethyl spinosad; (4) competitive modulators of nicotinic acetylcholine receptors (nAChRs): clothianidin, acetamiprid, (5) Allosteric regulators of glutamate-gated chloride channels (GluCl): avermectin benzoate, avermectin; (6) Inhibitors of chitin biosynthesis that affect CHS1: lufenuron, flufenoxuron; (7) Chitin biosynthesis inhibitor: thiamethoxam; (8) Ecdysone receptor agonist: methoxyfenozide; (9) Voltage-dependent sodium ion channel blockers: indoxacarb; (10) Rhododendron receptor modulators: bromocyanamide, tetrachlorantraniliprole, tetrazolium amide; (11) GABA-gated chloride channel allosteric modulators: brofenoxam, isoxazolamide, Oxadiazon; (12) Sodium ion channel modulators: ethoxysulfuron, deltamethrin, cypermethrin, bifenthrin; (13) Acetyl-CoA carboxylase inhibitor: Bispira taurus; (14) Nicotinamide inhibitors for string instruments: flunitrazide, trifluoromethylnicotinamide; (15) Chordotonal organ TRPV channel modulators: indoxamate, (16) Inhibitor of mitochondrial electron transport complex (I): pyridaben; (17) Other:

2. The insecticidal composition according to claim 1, characterized by, The weight ratio of active ingredient A to active ingredient B is 200:1-1:300, 100:1-1:200, 50:1-1:100, 40:1-1:50, 20:1-1:20, 10:1-1:10, 8:1-1:5, 5:1-1:2, or 2:1-1:

1.

3. The insecticidal composition according to claim 1 or 2, characterized by, The active ingredients A and B account for 1-95% of the total mass, preferably 5-80%.

4. The insecticidal composition according to claim 1 or 2, characterized by, The insecticidal composition also includes conventional adjuvants, preferably one or more of surfactants, binders, thickeners, colorants, antifreeze agents, anti-caking agents, disintegrants, and decomposition inhibitors.

5. The insecticidal composition according to claim 1 or 2, characterized by, The specific formulations of the insecticidal composition are aqueous suspensions, emulsion suspensions, emulsions, liquids, wettable powders, wettable granules, granules, powders, microcapsules, capsules, tablets, large granules, or bags.

6. The use of the insecticidal composition according to any one of claims 1-5 for the prevention or control of harmful organisms that invade crops or crop propagation material.

7. Use according to claim 6, characterized in that, The harmful organisms mentioned are lepidopteran pests, coleopteran pests, and homoptera pests.

8. A method of preventing or controlling a pest, characterized by, The insecticidal composition according to any one of claims 1-5 is used on the target pest and / or its environment.

9. A method of preventing or controlling a pest, characterized by, The insecticidal composition according to any one of claims 1-5 is applied to seeds, the target crop, or the soil in which the target crop grows or soil suitable for the growth of the target crop.

10. A method of protecting a target crop from attack by pests, characterised in that, The insecticidal composition according to any one of claims 1-5 is brought into contact with the target crop, the target pest and / or its environment, or the reproductive material of the target crop.

Images