Stable synergistic fungicidal composition

Abstract

The present invention relates to stable synergistic fungicidal composition for synergistic and effective control of various stages of fungal growth in crops. Further, the present invention also relates to a process for preparation of such fungicidal composition for synergistic and efficacious control of wide range of fungal diseases.

Description

[0001] STABLE SYNERGISTIC FUNGICIDAL COMPOSITION

[0002] FIELD OF THE INVENTION

[0003] The present invention relates to a stable synergistic fungicidal composition comprising A) Myclobutanil or its agrochemically acceptable salts, esters and derivatives; B) Mancozeb or its agrochemically acceptable salts, esters and derivatives; and C) Tebuconazole or its agrochemically acceptable salts, esters or its derivatives for effective control of various fungal diseases. Further, the present invention also relates to a process for preparation of such fungicidal composition for synergistic and efficacious control of wide range of fungal diseases.

[0004] BACKGROUND OF THE INVENTION

[0005] The impact of plant diseases on agricultural productivity cannot be overstated, particularly in the context of vegetable, field, cereal, and fruit crops for example but not limited to grapes. Fungal pathogens which are considered as one of the primary causes can lead to significant reductions in crop yield and quality, ultimately imposing increased costs on consumers. Additionally Fungal pathogens infect crops through multiple mechanisms and at different stages of development. Effective management of these diseases through the use of fungicides is therefore crucial for achieving optimal agricultural efficiency. Despite the availability of numerous commercial fungicides, there is an ongoing need for new and innovative compositions that exhibit enhanced efficacy, broad spectrum of action, lower costs, reduced toxicity, and improved environmental safety. Additionally, fungicides with distinct modes of action are essential to mitigate the rapid development of resistance observed in fungal populations.

[0006] Although a wide range of fungicides is commercially available, the effective control of fungal diseases remains challenging. Many fungal pathogens exhibit rapid adaptability, leading to reduced sensitivity or resistance to fungicides after repeated use. Consequently, fungicides having different and complementary modes of action are required to delay resistance development and ensure effective fungal disease control. However, effectiveness of these existing compositions,, can vary significantly based on factors such as the specific crop type, the fungal pathogen involved, and the environmental conditions during treatment.In the context of existing fungicidal compositions, several critical challenges remain unaddressed. As fungal diseases are further complicated by variations in crop species, pathogen types, and environmental conditions. In agricultural settings, single-active fungicides often fail to deliver consistent performance, especially under high disease pressure or adverse climatic conditions such as rainfall, which can reduce residual activity and wash off applied formulations. As a result, farmers increasingly rely on combinations of fungicides to achieve broader spectrum control, improved persistence, and enhanced efficacy.

[0007] Further, despite the widespread use of fungicidal compositions, several limitations persist in existing formulations Many current formulations suffer from reduced efficacy during rainfall events — an occurrence that can wash away active ingredients and render treatments ineffective. This underscores a pressing need within the agricultural community for fungicides that possess multiple modes of action, broaden the range of fungal disease control, and demonstrate improved rain-fastness. Furthermore, formulations must minimize or eliminate phytotoxic effects on desirable plants while providing synergistic control of fungal diseases at reduced dosages.

[0008] The development of high concentrations of fungicides can lead to toxicity concerns for human health and detrimental environmental effects. Therefore, there is an urgent demand for cost-effective, synergistic fungicidal compositions that address resistance issues and soil toxicity while allowing for reduced application rates. Such compositions should aim to minimize environmental impact, offer broader crop protection, promote healthy foliage, enhance rain-fastness, improve crop yield, reduce labor costs, and effectively control a diverse array of fungal diseases. Additionally, these formulations should support plant growth, be environmentally friendly, non-phytotoxic, and economically viable for end-users.

[0009] Existing fungicidal compositions often adversely affect plants, leading to problems such as leaf discoloration and the emergence of resistance in fungal pathogens. Moreover, many of these formulations lack effectiveness against all life stages of fungal pathogens, highlighting the necessity for innovative solutions. Consequently, there is a critical need for new fungicidal compositions that can provide a range of options to meet the specific needs of plant disease control, ensuring sustainable agricultural practices and protecting crop health.Fungicides acting through a single biochemical pathway often fail to provide consistent and durable disease control, particularly under high disease pressure and repeated application. Moreover, continuous exposure to a single mode of action accelerates the development of resistance in fungal populations. Stable synergistic fungicidal composition of the present invention addresses these challenges to overcome the limitations of existing products, offering a synergistic approach to fungal disease control that is effective, environmentally friendly, and economically sustainable.

[0010] It has been observed by the inventors of the present invention that the composition of present invention not only has enhances bio-efficacy and provides synergistic effect but also gives control of wide range of fungal diseases for a longer duration as compared to solo and binary formulations of fungicides.

[0011] Azole fungicides are a class of chemical compounds widely used in agriculture to control fungal diseases in crops. They are known for their broad-spectrum activity, effectiveness and relatively low toxicity. Azole fungicides, including myclobutanil and tebuconazole, are widely used due to their systemic nature and effectiveness in inhibiting ergosterol biosynthesis.

[0012] Myclobutanil, chemically known as α-butyl-α-(4-chlorophenyl)-1H-1,2,4-triazole-1-propanenitrile is a selective fungicide used to control wide range of plant diseases. Myclobutanil disrupts fungal membrane function by inhibiting the production of ergosterol, a vital component of sterol biosynthesis. It inhibits sterol 14-demethylase enzyme, which produces ergosterol an essential component for the formation of fungal cell wall. Myclobutanil is a fungicide used to control of a wide range of pathogens including blights and scabs on crops.

[0013] Tebuconazole is a triazole fungicide, and is also known as a DMI (demethylation inhibiting fungicide). It's considered fungistatic, or growth-inhibiting, rather than fungicidal, or funguskilling. It also works by inhibiting the synthesis of ergosterol. This prevents the growth and reproduction of pathogens, and slows or stops the formation of fungus. Tebuconazole is effective against various foliar diseases in cereals and other field crops.Mancozeb is a non-systemic fungicide that disrupts fungal cell metabolism by interfering with enzymes that contain sulfhydryl groups. This disrupts biochemical processes in the fungal cell's mitochondria and cytoplasm, which inhibits or interferes with multiple processes. Mancozeb is classified as a multi-site fungicide by the Fungicide Resistance Action Committee (FRAC) and used for controlling the wide range of pathogens including blights and scabs on crops.

[0014] Accordingly, the present invention provides a synergistic fungicidal composition comprising myclobutanil, tebuconazole, and mancozeb in bio-effective amounts, and suitable agrochemical excipients offering durable, broad-spectrum, and environmentally acceptable control of fungal diseases.

[0015] The present invention satisfies the existing needs, as well as others, and generally overcomes the deficiencies found in the prior art. The synergistic fungicidal composition of the present invention is synergistic, efficacious, environmentally friendly, cost-effective, simple to formulate, stable and is safe to use

[0016] Thus, a fungicidal composition of the present invention aims to overcome the problems of the prior art and provide a stable synergistic fungicidal composition comprising bioactive amounts of synergistic fungicidal composition comprising A) Myclobutanil or its agrochemically acceptable salts, esters and derivatives; B) Mancozeb or its agrochemically acceptable salts, esters and derivatives; and C) Tebuconazole or its agrochemically acceptable salts, esters or its derivatives for synergistic and effective control of wide range of fungal diseases.

[0017] OBJECTIVES AND ADVANTAGES OF THE INVENTION

[0018] The principal objective of the present invention is to provide a novel and effective synergistic fungicidal composition demonstrating high efficacy and to provide complete protection to crops, plants against wide range of fungal diseases.

[0019] It is another objective of the present invention to provide improved, stable and ready to use fungicidal composition having synergistic and superior properties compared to prior art formulations or mixtures or compositions.It is yet another objective of the present invention to provide a method and a stable synergistic fungicidal composition for controlling broad spectrum of fungal diseases.

[0020] Yet another objective of the present invention is to facilitate effective antifungal formulation by developing an advanced broad- spectrum fungicidal combination. Another objective of the present invention is to provide selective effectiveness while significantly reducing adverse effects on nontarget organisms, particularly beneficial species, thus promoting ecological balance.

[0021] Yet another objective of the present invention is to provide improved, stable and ready to use fungicidal composition that demonstrates superior synergistic efficacy compared to existing formulations, mixtures or compositions ensuring improved control of fungal diseases. Yet another objective of the present invention to provide a novel and effective synergistic fungicidal composition effectively targeting all life stages of fungi and promoting overall plant health and crop yield.

[0022] Another objective of the present invention is to provide one shot application of novel and effective synergistic fungicidal composition for killing / controlling highly resistant fungi at lower application rates.

[0023] It is another objective of the present invention to provide a novel and effective synergistic fungicidal composition which is environmentally safe, possesses broad spectrum bio-efficacy, is non-phytotoxic and has improved stability during the desired shelf life at various temperature and pH conditions and has enhanced efficacy and penetration capacity and is economically more beneficial.

[0024] It is another objective of the present invention to provide a novel and effective synergistic fungicidal composition which further comprises additives, inert ingredients and / or adjuvants, for providing the enhanced stability, enhanced permeability, improved penetration capacity, uniform spray-ability, improved rain-fastness, enriched biotic factors, better flowability, enhanced spreading or coverage effect, effective storage stability, longer residual effect, improved uptake of active ingredients, and safer to the environment attributes to the composition of present invention.Yet another objective of present invention is to provide a synergistic fungicidal composition that improves germination rate, increased plants stand count and plant health, which results in higher yield.

[0025] Another objective of the present invention is to provide a stable synergistic fungicidal composition comprising A) Myclobutanil or its agrochemically acceptable salts, esters and derivatives; B) Mancozeb or its agrochemically acceptable salts, esters and derivatives; and C) Tebuconazole or its agrochemically acceptable salts, esters or its derivatives for effective control of various fungal diseases.

[0026] Further, the present invention also relates to a process for preparation of such fungicidal composition for synergistic and efficacious control of wide range of fungal diseases.

[0027] Yet another objective of the present invention is to provide a process for the preparation of a stable synergistic fungicidal composition comprising A) Myclobutanil or its agrochemically acceptable salts, esters and derivatives; B) Mancozeb or its agrochemically acceptable salts, esters and derivatives; and C) Tebuconazole or its agrochemically acceptable salts, esters or its derivatives for effective control of various fungal diseases.

[0028] Some or all these and other objects of the invention can be achieved by way of the invention described hereinafter.

[0029] ADVANTAGES:

[0030] 1. The stable synergistic fungicidal composition of the present invention has the advantage of being highly active against fungal plant pathogens in the soil that mostly occur in the early stages of plant development.

[0031] 2. The stable synergistic fungicidal composition of the present invention resulted in significantly lower incidence of fungal diseases in various crops.

[0032] 3. The stable synergistic fungicidal composition of the present invention is significantly superior and synergistic from its individual products at lower or equal dose.4. The stable synergistic fungicidal composition of the present invention provides higher marketable yields as compared to the untreated control and binary and solo treatments applied in the various crops.

[0033] 5. The stable synergistic fungicidal composition of the present invention is found to be economical with higher Cost: Benefit Ratio.

[0034] 6. The stable synergistic fungicidal composition can be applied to various crops including but not limited to table grapes, annual crops, turf, bananas, sugarcane, landscape ornamentals, fruit trees, vines, potatoes, fruit including apples, pears, grapes, cotton, corn, sunflowers, peanuts, tomatoes, cereals, ornamental shrubs including roses, wheat, barley, oat, rye, peanuts, vegetables including onions, peas, pepper, etc.

[0035] 7. The stable synergistic fungicidal composition provides increased uptake of active ingredients.

[0036] 8. The stable synergistic fungicidal composition shows no phytotoxicity.

[0037] 9. The stable synergistic fungicidal composition of the present invention provides long- lasting protection, reducing the need for frequent and multiple re-applications.

[0038] 10. The stable synergistic fungicidal composition of the present invention is storage stable.

[0039] 11. The stable synergistic fungicidal composition of the present invention promotes plant health and increases plant yield in the field.

[0040] 12. The stable synergistic fungicidal composition of the present invention decreases the chances of resistance against wide range of fungal diseases.

[0041] 13. The stable synergistic fungicidal composition of present invention has improved rain fastness.

[0042] SUMMARY OF THE INVENTION

[0043] Accordingly, the main aspect of the present invention is to provide a stable synergistic fungicidal composition having high fungal disease control efficacy.

[0044] Accordingly, the present invention relates to a stable synergistic fungicidal composition comprising:

[0045] A) Myclobutanil or its agrochemically acceptable salts, esters and derivatives;

[0046] B) Mancozeb or its agrochemically acceptable salts, esters and derivatives; andC) Tebuconazole or its agrochemically acceptable salts, esters or its derivatives.

[0047] In another aspect, the present invention provides a stable synergistic fungicidal composition comprising:

[0048] A) Myclobutanil or its agrochemically acceptable salts, esters and derivatives;

[0049] B) Mancozeb or its agrochemically acceptable salts, esters and derivatives;

[0050] C) Tebuconazole or its agrochemically acceptable salts, esters or its derivatives; and

[0051] D) One or more agrochemically acceptable excipients.

[0052] In another aspect, the present invention relates to a stable synergistic fungicidal composition comprising:

[0053] A) Myclobutanil or its agrochemically acceptable salts, esters and derivatives;

[0054] B) Mancozeb or its agrochemically acceptable salts, esters and derivatives; and

[0055] C) Tebuconazole or its agrochemically acceptable salts, esters or its derivatives.

[0056] D) At least one or more additives.

[0057] In one another aspect, the present invention provides a stable synergistic fungicidal composition comprising:

[0058] A) Myclobutanil or its agrochemically acceptable salts, esters and derivatives;

[0059] B) Mancozeb or its agrochemically acceptable salts, esters and derivatives;

[0060] C) Tebuconazole or its agrochemically acceptable salts, esters or its derivatives;

[0061] D) Additive selected from urea clathrate, Siloxane Polyalkyleneoxide Copolymer, tallow amine ethoxylate, ammonium sulphate, and epoxide soybean oil either alone or in combination thereof; and

[0062] E) One or more agrochemically acceptable excipients.In one another aspect, the present invention provides a stable synergistic fungicidal composition comprising:

[0063] A) Myclobutanil or its agrochemically acceptable salts, esters and derivatives, in the range of 0.001-90% by weight of the composition;

[0064] B) Mancozeb or its agrochemically acceptable salts, esters and derivatives, in the range of 0.001-90% by weight of the composition; and

[0065] C) Tebuconazole or its agrochemically acceptable salts, esters or its derivatives in the range of 0.001-90% by weight of the composition.

[0066] In one another aspect, the present invention provides a stable synergistic fungicidal composition comprising:

[0067] A) Myclobutanil or its agrochemically acceptable salts, esters and derivatives, in the range of 0.001-90% by weight of the composition;

[0068] B) Mancozeb or its agrochemically acceptable salts, esters and derivatives, in the range of 0.001-90% by weight of the composition;

[0069] C) Tebuconazole or its agrochemically acceptable salts, esters or its derivatives in the range of 0.001-90% by weight of the composition; and

[0070] D) One or more agrochemically acceptable excipients.

[0071] In one another aspect, the present invention provides a stable synergistic fungicidal composition comprising:

[0072] A) Myclobutanil or its agrochemically acceptable salts, esters and derivatives, in the range of 0.001-90% by weight of the composition;

[0073] B) Mancozeb or its agrochemically acceptable salts, esters and derivatives, in the range of 0.001-90% by weight of the composition;

[0074] C) Tebuconazole or its agrochemically acceptable salts, esters or its derivatives in the range of 0.001-90% by weight of the composition; andD) At least one or more additives.

[0075] In one another aspect, the present invention provides a stable synergistic fungicidal composition comprising:

[0076] A) Myclobutanil or its agrochemically acceptable salts, esters and derivatives, in the range of 0.001-90% by weight of the composition;

[0077] B) Mancozeb or its agrochemically acceptable salts, esters and derivatives, in the range of 0.001 - 90% by weight of the composition;

[0078] C) Tebuconazole or its agrochemically acceptable salts, esters or its derivatives in the range of 0.001-90% by weight of the composition;

[0079] D) Additive selected from urea clathrate, Siloxane Polyalkyleneoxide Copolymer, tallow amine ethoxylate, ammonium sulphate, and epoxide soybean oil either alone or in combination thereof, in the range of 0.001-20% by weight of the composition; and

[0080] E) One or more agrochemically acceptable excipients.

[0081] In yet another aspect, the present invention provides a process for preparation of the stable synergistic fungicidal composition comprising:

[0082] A) Myclobutanil or its agrochemically acceptable salts, esters and derivatives;

[0083] B) Mancozeb or its agrochemically acceptable salts, esters and derivatives; and

[0084] C) Tebuconazole or its agrochemically acceptable salts, esters or its derivatives.

[0085] In an aspect of the present invention, the present invention provides a stable synergistic fungicidal composition which further comprises additives and / or adjuvants, for providing the following attributes to the composition of present invention:

[0086] a) enhanced stability, permeability, and spreading or coverage effect,

[0087] b) improved penetration capacity, and improved rain-fastness,

[0088] c) uniform spray-ability, storage stability, and longer residual effect,

[0089] d) enriched biotic factors, and better flowability,

[0090] e) improved uptake of active ingredients, andf) safer to the environment.

[0091] In another aspect, the present synergistic fungicidal composition is stable and has enhanced shelf life and effectively control wide range of fungal diseases.

[0092] In another aspect, the present invention provides a stable synergistic fungicidal composition which has enhanced efficacy and penetration capacity.

[0093] In another aspect, the present invention provides a stable synergistic fungicidal composition which is economically beneficial to the farmers and storage stable.

[0094] DETAILED DESCRIPTION OF THE INVENTION

[0095] In describing the embodiments of the invention, specific terminology is resorted for sake of clarity. However, it is not intended that the invention be limited to specific terms so selected and it is to be understood that each specific term includes all technical equivalents that operate in a similar manner to accomplish a similar purpose.

[0096] It has been observed by the inventors of the present invention that the composition of present invention not only provides synergistic effect but also provides anti-aging effect to the crops or plants to which it is applied. In addition, the stable synergistic fungicidal composition of the present invention is effective against all developmental stages of fungal pathogens.

[0097] Discussed below are some representative embodiments of the present invention. The invention in its broader aspects is not limited to the specific details and representative methods.

[0098] All technical and scientific terms used herein have the same meanings as commonly understood by someone ordinarily skilled in the art to which the present subject matter belongs.

[0099] The terminology used, in the present disclosure, is only for the purpose of explaining a particular embodiment and such terminology shall not be considered to limit the scope of the present disclosure.

[0100] As used in the present disclosure, the forms "a,” "an," and "the" may be intended to include the plural forms as well, unless the context clearly suggests otherwise. Thus, for example, reference to a composition containing “a compound” includes a mixture of two or more compounds. It shouldalso be noted that the term “or” is generally employed in its sense including “and / or” unless the content clearly dictates otherwise.

[0101] The terms "comprise / comprises", "comprising", “including”, and “having” are open ended transitional phrases and therefore specify the presence of stated features, integers, steps, operations, elements, but do not forbid the presence or addition of one or more other features, integers, steps, operations, elements, components, and / or groups thereof. The particular order of steps disclosed in the method and process of the present disclosure is not to be construed as necessarily requiring their performance as described or illustrated. It is also to be understood that additional or alternative steps may be employed.

[0102] Variations or modifications to the composition of this invention, within the scope of the invention, may occur to those skilled in the art upon reviewing the disclosure herein. Such variations or modifications are well within the spirit of this invention.

[0103] The expression of various quantities in terms of “% w / w” or “%” means the percentage by weight, relative to the weight of the total solution (i.e., % w / w) or volume of total solution (i.e., % w / v), composition unless otherwise specified.

[0104] The term “active ingredient” (a.i.) or “active agent” or “active” used herein refers to that component of the composition responsible for control of various fungal diseases at the same time. The term “crop” shall include a multitude of desired crop plants or an individual crop plant growing at a locus.

[0105] The term “synergistic”, as used herein, refers to the combined action of two or more active agents blended together and administered conjointly that is greater than the sum of their individual effects. “Bioactive amounts” as mentioned herein means that amount which, when applied for treatment of crops, is sufficient to give effect in such treatment.

[0106] The term “control”, with respect to fungal diseases, refers to the suppression, prevention, reduction, or inhibition of the ability of fungal pathogens to infect, survive, grow, sporulate, spread, and / or reproduce, or to limit the disease -related damage or yield loss in crop plants. Control of fungal diseases may or may not result in the death of the fungal pathogen, although such control preferably involves fungicidal activity.The term “health of a plant” or “plant health” is defined as a condition of the plant and / or its products. As a result of the improved health; yield, plant vigour, quality and tolerance to abiotic or biotic stress is increased. As a result, the health of a plant is increased even in the absence of disease pressure.

[0107] Accordingly, in an especially preferred embodiment according to the invention, the health of a plant is increased both in the presence and absence of biotic or abiotic stress factors. An increase in plant vigor may for example results in an increased yield and / or tolerance to abiotic or biotic stress.

[0108] One indicator for the condition of the plant is the yield. “Yield” is to be understood as any plant product of economic value that is produced by the plant such as grains, fruits, vegetables, nuts, grains, seeds, wood (e.g., in the case of silviculture plants) or even flowers (e.g. in the case of gardening plants, ornamentals). The plant products may in addition be further utilized and / or processed after harvesting.

[0109] According to embodiments of the present invention, the yield of the target plants treated according to the method of the invention, is increased synergistically.

[0110] According to embodiments of the invention, the plant vigour of the treated plant is increased. In another preferred embodiment of the invention, the plant vigour of the plants treated according to the composition of the present invention is increased synergistically.

[0111] Another indicator for the condition of the plant is the “quality” of a plant and / or its products. According to embodiments of the invention, the quality of the treated plant is increased.

[0112] In preferred embodiment of the invention, the quality of the plants treated according to the method of the invention, is increased synergistically.

[0113] The term rain fastness refers to the ability of a substance to remain effective after being applied to a surface and then exposed to rainfall or irrigation. In other words, it measures how well the substance adheres to the target surface and resists being washed away by water. A low rain fastness indicates that it may be washed off or diluted by rainfall, reducing its efficacy.The term " Increased uptake of active ingredient" refers to the enhanced absorption or penetration of the active component of a substance into the target organism or plant. It may occur through various mechanisms, such as improved formulation, adjuvants that enhance penetration, or modifications to the active ingredient itself to facilitate absorption. Overall, increased uptake of the active ingredient results in improved performance of the product in achieving its intended purpose.

[0114] The term “benefit: cost” refers to a ratio used in a cost -benefit analysis to summarize the overall relationship between the relative costs and benefits of a proposed composition. If a treatment has a benefit-cost ratio greater than 1.0, the treatment is expected to deliver a positive and better outcome.

[0115] According to embodiments of the present invention, the yield of the treated plant is increased. According to embodiments of the present invention, there is synergistic and efficacious control of various fungal diseases affecting the plants and crops.

[0116] Another embodiment of the present invention, includes within its scope, all possible salts, esters and derivatives of the active ingredients of the composition.

[0117] It is also to be understood that the terminology used herein is for the purpose of describing particular embodiments of the invention only and is not intended to limit the scope of the invention in any manner. The use of examples anywhere in this specification including examples of any terms discussed herein is illustrative only, and in no way limits the scope and meaning of the invention or of any exemplified term. Likewise, the invention is not limited to various embodiments given in this specification.

[0118] Unless indicated otherwise, the technical and scientific terms employed herein shall be construed in accordance with their conventional meaning as understood by a person skilled in the relevant art. In the event of any inconsistency, the definitions and explanations set forth in the present specification shall prevail.

[0119] The composition or formulation according to the present invention has a reduced or zero phytotoxicity with respect to agricultural crops.The term “active ingredient” (a.i.) or “active agent” or “active” used herein refers to that component of the composition responsible for preventing and controlling the fungal disease. In an embodiment, the present invention provides a stable synergistic fungicidal composition comprising:

[0120] A) Myclobutanil or its agrochemically acceptable salts, esters and derivatives;

[0121] B) Mancozeb or its agrochemically acceptable salts, esters and derivatives; and

[0122] C) Tebuconazole or its agrochemically acceptable salts, esters or its derivatives.

[0123] In another embodiment, the present invention provides a stable synergistic fungicidal composition comprising:

[0124] A) Myclobutanil or its agrochemically acceptable salts, esters and derivatives;

[0125] B) Mancozeb or its agrochemically acceptable salts, esters and derivatives;

[0126] C) Tebuconazole or its agrochemically acceptable salts, esters or its derivatives; and

[0127] D) One or more agrochemically acceptable excipients.

[0128] In another embodiment, the present invention provides a stable synergistic fungicidal composition comprising:

[0129] A) Myclobutanil or its agrochemically acceptable salts, esters and derivatives;

[0130] B) Mancozeb or its agrochemically acceptable salts, esters and derivatives;

[0131] C) Tebuconazole or its agrochemically acceptable salts, esters or its derivatives; and

[0132] D) At least one or more additives.

[0133] In one another embodiment, the present invention provides a stable synergistic fungicidal composition comprising:

[0134] A) Myclobutanil or its agrochemically acceptable salts, esters and derivatives;

[0135] B) Mancozeb or its agrochemically acceptable salts, esters and derivatives;C) Tebuconazole or its agrochemically acceptable salts, esters or its derivatives;

[0136] D) Additive selected from urea clathrate, Siloxane Polyalkyleneoxide Copolymer, tallow amine ethoxylate, ammonium sulphate, and epoxide soybean oil either alone or in combination thereof; and

[0137] E) One or more agrochemically acceptable excipients.

[0138] In one another embodiment, the present invention provides a stable synergistic fungicidal composition comprising:

[0139] A) Myclobutanil or its agrochemically acceptable salts, esters and derivatives, in the range of 0.001-90% by weight of the composition;

[0140] B) Mancozeb or its agrochemically acceptable salts, esters and derivatives, in the range of 0.001-90% by weight of the composition; and

[0141] C) Tebuconazole or its agrochemically acceptable salts, esters or its derivatives in the range of 0.001-90% by weight of the composition.

[0142] In one another embodiment, the present invention provides a stable synergistic fungicidal composition comprising:

[0143] A) Myclobutanil or its agrochemically acceptable salts, esters and derivatives, in the range of 0.001-90% by weight of the composition;

[0144] B) Mancozeb or its agrochemically acceptable salts, esters and derivatives, in the range of 0.001-90% by weight of the composition;

[0145] C) Tebuconazole or its agrochemically acceptable salts, esters or its derivatives in the range of 0.001-90% by weight of the composition; and

[0146] D) One or more agrochemically acceptable excipients.

[0147] In one embodiment, the present invention provides a stable synergistic fungicidal composition comprising:A) Myclobutanil or its agrochemically acceptable salts, esters and derivatives, in the range of 0.001- 90% by weight of the composition;

[0148] B) Mancozeb or its agrochemically acceptable salts, esters and derivatives, in the range of 0.001-90% by weight of the composition;

[0149] C) Tebuconazole or its agrochemically acceptable salts, esters or its derivatives in the range of 0.001- 90% by weight of the composition; and

[0150] D) At least one or more additives.

[0151] In one another embodiment, the present invention provides a stable synergistic fungicidal composition comprising:

[0152] A) Myclobutanil or its agrochemically acceptable salts, esters and derivatives, in the range of 0.001-90% by weight of the composition;

[0153] B) Mancozeb or its agrochemically acceptable salts, esters and derivatives, in the range of 0.001 - 90% by weight of the composition;

[0154] C) Tebuconazole or its agrochemically acceptable salts, esters or its derivatives in the range of 0.001-90% by weight of the composition;

[0155] D) Additive selected from urea clathrate, Siloxane Polyalkyleneoxide Copolymer, tallow amine ethoxylate, ammonium sulphate, and epoxide soybean oil either alone or in combination thereof, in the range of 0.001-20% by weight of the composition; and

[0156] E) One or more agrochemically acceptable excipients.

[0157] In one another preferred embodiment, the present invention provides a stable synergistic fungicidal composition comprising:

[0158] A) Myclobutanil or its agrochemically acceptable salts, esters and derivatives, in the range of 0.001-30% by weight of the composition;

[0159] B) Mancozeb or its agrochemically acceptable salts, esters and derivatives, in the range of 0.001-70% by weight of the composition; andC) Tebuconazole or its agrochemically acceptable salts, esters or its derivatives in the range of 0.001-40% by weight of the composition.

[0160] In one another preferred embodiment, the present invention provides a stable synergistic fungicidal composition comprising:

[0161] A) Myclobutanil or its agrochemically acceptable salts, esters and derivatives, in the range of 0.001-30% by weight of the composition;

[0162] B) Mancozeb or its agrochemically acceptable salts, esters and derivatives, in the range of 0.001-70% by weight of the composition;

[0163] C) Tebuconazole or its agrochemically acceptable salts, esters or its derivatives in the range of 0.001-40% by weight of the composition; and

[0164] D) One or more agrochemically acceptable excipients.

[0165] In one another preferred embodiment, the present invention provides a stable synergistic fungicidal composition comprising:

[0166] A) Myclobutanil or its agrochemically acceptable salts, esters and derivatives, in the range of 0.001-30% by weight of the composition;

[0167] B) Mancozeb or its agrochemically acceptable salts, esters and derivatives, in the range of 0.001-70% by weight of the composition;

[0168] C) Tebuconazole or its agrochemically acceptable salts, esters or its derivatives in the range of 0.001-40% by weight of the composition; and

[0169] D) At least one or more additives.

[0170] In one another preferred embodiment, the present invention provides a stable synergistic fungicidal composition comprising:

[0171] A) Myclobutanil or its agrochemically acceptable salts, esters and derivatives, in the range of 0.001-30% by weight of the composition;B) Mancozeb or its agrochemically acceptable salts, esters and derivatives, in the range of 0.001 - 70% by weight of the composition;

[0172] C) Tebuconazole or its agrochemically acceptable salts, esters or its derivatives in the range of 0.001-40% by weight of the composition;

[0173] D) Additive selected from urea clathrate, Siloxane Polyalkyleneoxide Copolymer, tallow amine ethoxylate, ammonium sulphate, and epoxide soybean oil either alone or in combination thereof, in the range of 0.001-20% by weight of the composition; and

[0174] E) One or more agrochemically acceptable excipients.

[0175] In one more preferred embodiment, the present invention provides a stable synergistic fungicidal composition comprising:

[0176] A) Myclobutanil or its agrochemically acceptable salts, esters and derivatives, in the range of 0.001-15% by weight of the composition;

[0177] B) Mancozeb or its agrochemically acceptable salts, esters and derivatives, in the range of 0.01-64% by weight of the composition; and

[0178] C) Tebuconazole or its agrochemically acceptable salts, esters or its derivatives in the range of 0.01-30% by weight of the composition.

[0179] In one another more preferred embodiment, the present invention provides a stable synergistic fungicidal composition comprising:

[0180] A) Myclobutanil or its agrochemically acceptable salts, esters and derivatives, in the range of 0.001-15% by weight of the composition;

[0181] B) Mancozeb or its agrochemically acceptable salts, esters and derivatives, in the range of 0.01-64% by weight of the composition;

[0182] C) Tebuconazole or its agrochemically acceptable salts, esters or its derivatives in the range of 0.01-30% by weight of the composition; and

[0183] D) One or more agrochemically acceptable excipients.In one another more preferred embodiment, the present invention provides a stable synergistic fungicidal composition comprising:

[0184] A) Myclobutanil or its agrochemically acceptable salts, esters and derivatives, in the range of 0.001-15% by weight of the composition;

[0185] B) Mancozeb or its agrochemically acceptable salts, esters and derivatives, in the range of 0.01-64% by weight of the composition;

[0186] C) Tebuconazole or its agrochemically acceptable salts, esters or its derivatives in the range of 0.01-30% by weight of the composition; and

[0187] D) At least one or more additives.

[0188] In one another more preferred embodiment, the present invention provides a stable synergistic fungicidal composition comprising:

[0189] A) Myclobutanil or its agrochemically acceptable salts, esters and derivatives, in the range of 0.001-15% by weight of the composition;

[0190] B) Mancozeb or its agrochemically acceptable salts, esters and derivatives, in the range of 0.01- 64% by weight of the composition;

[0191] C) Tebuconazole or its agrochemically acceptable salts, esters or its derivatives in the range of 0.01-30% by weight of the composition;

[0192] D) Additive selected from urea clathrate, Siloxane Polyalkyleneoxide Copolymer, tallow amine ethoxylate, ammonium sulphate, and epoxide soybean oil either alone or in combination thereof, in the range of 0.001-20% by weight of the composition; and

[0193] E) One or more agrochemically acceptable excipients.

[0194] In an embodiment, Mancozeb can be in the form of zinc or manganese salts, etc. In accordance with an embodiment of the present invention, there is provided a stable synergistic fungicidal composition comprising active ingredients present in the weight % range as given below:S. No Active ingredients Wt % (% w / w or %w / v) 1 Myclobutanil or its agrochemically acceptable salts, 0.001-90%

[0195] esters and derivatives

[0196] 2 Mancozeb or its agrochemically acceptable salts, 0.001-90%

[0197] esters and derivatives

[0198] 3 Tebuconazole or its agrochemically acceptable salts, 0.001-90%

[0199] esters or its derivatives

[0200]

[0201] According to the embodiments of the present invention, the synergistic fungicidal composition result in the increased yield of the treated plant.

[0202] According to the embodimentsof the invention, there is synergistic and efficacious control of various fungal diseases affecting the plants and crops.

[0203] In an embodiment, the present invention includes within its scope, all possible salts, esters and derivatives of the active ingredients of the composition.

[0204] According to the embodiments of the present invention, a stable synergistic fungicidal composition or formulation according to the present invention has a reduced or zero phytotoxicity with respect to important agricultural crops. This results in the present invention effective and possible in the selective control of fungal diseases.

[0205] In an embodiment of the present invention, the stable synergistic fungicidal composition further optionally comprises additives, inert ingredients and / or adjuvants, for providing the following attributes to the composition of present invention:

[0206] a) enhanced stability, permeability, and spreading or coverage effect

[0207] b) improved penetration capacity, and storage stability,

[0208] c) uniform spray-ability, and improved rain-fastness,

[0209] d) enriched biotic factors, and better flowability,

[0210] e) longer residual effect, and improved uptake of active ingredients, and safer to the environment.In an embodiment of the present invention, the stable synergistic fungicidal composition of the present invention further comprises one or more agrochemically acceptable excipients including but not limited to the group comprising surfactant(s), dispersing agent(s), co-dispersant, antifreezing agent(s), emulsifier(s) (anionic and non-ionic), anti-foaming agent / defoamer(s), wetting agent(s), antimicrobial / anti-bacterial agent(s), anti-caking agent, thickening agent / thickener(s), quick coating agent(s) or sticking agents / sticker(s), spreader(s), binder(s), pH-adjusting agent(s), anti-caking agent(s), adjuvant(s), filler(s) / suspension aid(s), colorant(s), carrier(s), buffering agent(s), polymer(s)rheology modifier(s), solvent(s), co-solvent(s), biocide or a combination thereof. Additional components may also be included, e.g., protective colloids, carriers, adhesives, thixotropic agents, penetration agents, stabilizers, sequestering agents. More generally, the active materials can be combined with any solid or liquid carrier / additive, which complies with usual formulation techniques.

[0211] An adjuvant used in the present invention is any material that is added to a fungicidal formulation to enhance or modify the performance of the formulation. Adjuvants used in the present invention to make it a safer to ecological environmental, having low toxicity and having no phytotoxicity effects on any part of the plant.

[0212] Examples of surfactant(s) and / or dispersing agent and / or co-dispersant used herein include but not limited to the group comprising polymeric anionic dispersant, polyarylphenyl ether phosphate, tristyryl phenol ethoxylate, Poly methyl methacrylate -polyethylene glycol graft copolymer, acrylate copolymer, acrylic copolymer, Ammonium Distyrylphenyl Ether Sulphate, Alkyl polyglucoside, Sodium lauryl sulphonate, polymeric dispersant, Calcium salt of alkyl benzene sulphonate, Calcium doceylbenzene sulphonate, Non-ionic surfactant, polyalkoxylated butyl ether, acrylic graft copolymer, Sodium methyl oleoyl taurate, non-ionic proprietary surfactant, Methyl naphthalene sulfonic acid, polymer with formaldehyde, sodium salt, ethoxylated tristryl phenol Sulphate, alkyl naphthalene formaldehyde condensate, sodium alkyl naphthalene sulfonate blend, naphthalene sulfonic acid, phenol sulfonic acid-formaldehyde polycondensation as sodium salt, sodium salt condensate with formaldehyde, ethoxylated oleyl cetyl alcohol, Acrylate graft Copolymer, Anionic tristyrylphenol phosphate surfactant, Sodium Alkyl Naphthalene Sulfonate Condensate, polyalkelene glycol ether, Sodium Isopropyl Naphthalene Sulfonate, Dialkylnaphthalene sulphonate sodium salt, Naphthalene Sulphonic Acid, Formaldehyde, Ethoxylated fatty glyceride, Ethoxylated Polyarylphenol Phosphate Ester, Lignosulfonic Acid, Sodium Salt, Sulfomethylated, ethoxylated fatty alcohol, methyl naphthalene sulfonic acid, polymer with formaldehyde sodium salt, Sodium polymethyl methacrylate, sodium polyacrylate, alkyl naphthalene sulfonate formaldehyde condensate or its sodium salt, Sodium Naphthalene Sulfonate formaldehyde condensate, Amine Salt of a Phosphated Tristyryl Phenol Ethoxylate, sodium lignosulphonate, calcium lignosulphonate, Sodium Alkyl Naphthalene Sulfonate, alkylphenol polyoxyethylene ether, sodium salt of naphthalene sulfonate condensate, alkyl naphthalene sulfonate condensate blend, polymeric surfactant, sodium salt of alkyl naphthalene sulfonate, sodium salt of methyl naphthalene sulfonate, lignosulphonate, polycarboxylate or its sodium salt, naphthalene sulfonic acid-branched and linear derivative sodium salts, fatty alcohol polyoxyethylene ether, alcohol polyglycol ether, non-aqueous dispersant - non-ionic polymeric surfactant, aqueous dispersant - polymeric amphoteric aqueous dispersant or mixtures thereof and present in the range of 0.01-20% by weight of the composition.

[0213] Examples of wetting agent used herein include but not limited to the group comprising tristyrylphenol ethoxylate non-ionic emulsifier, mixture of non-ionic surfactants, Blend of Anionic and Non-ionic, Sodium dioctyl sulfosuccinate, alkoxylated alcohol, block copolymer, alcohol polyglycol ether, Polyalkyleneoxide modified polydimethylsiloxane, alkyl olefin sulphates, dioctyl sulpho succinate, alkyl naphthalene sulphate, Di-isopropyl Napthalene sulphonate, Benzenesulfonic acid, Hydroxy polymer with formaldehyde, Phenol and Urea sodium salt, Polyalkoxy ethers, alkyl phenol ethoxylates, tri-styrenated phenol ethoxylate, EO / PO block copolymers, butyl polyalkylene oxide block copolymer, sodium lauryl sulphate, sodium sulphates or mixtures thereof and present in the range of 0.001-20% by weight of the total composition.

[0214] Examples of defoamer or antifoaming agent used herein include but not limited to the group comprising silicon emulsion based anti-foam agents, Siloxane polyalkyleneoxide, Polydimethylsiloxane, trisiloxane ethoxylates, silicone oil, silicone compound, C10～C20 saturated fat acid compounds or C8～C10 aliphatic alcohols compound, vegetable oil based antifoam, tallow based fatty acids, polyalkyleneoxide polydimethylsiloxane emulsion and mixtures thereof and present in the range of 0.001-5.0 % by weight of the composition.Examples of anti-freezing agent used herein include but not limited to the group comprising glycol, propylene glycol, mono ethylene glycol, glycerine, diethylene glycol, sorbitol, urea, mannitol, Aluminum Magnesium Silicate, polyethylene glycol or mixtures thereof and present in the range of 0.01-20% by weight of the composition.

[0215] Examples of filler used herein include but not limited to the group comprising silicon dioxide, China-clay, kaolin, starch, bentonite, precipitated silica, fumed silica, lactose monohydrate, talcum powder, lactose, ammonium sulphate, water, sodium Sulphate, magnesium sulphate, sodium citrate, sodium chloride, potassium chloride and mixtures thereof and present in the range of 0.001 -60 % by weight of the composition.

[0216] Examples of anti-caking agent used herein include but not limited to the group comprising of talc, hydrous magnesium silicate, magnesium carbonate, calcium carbonate, precipitate silica, silica powder, hydrophobic fumed silica and mixtures thereof and present in the range of 0.001-10% by weight of the composition.

[0217] Examples of carrier used herein include but not limited to the group comprising of silicon dioxide, china clay, kaolin, starch, bentonite, precipitated silica, silica powder, fumed silica, lactose monohydrate, talcum powder, lactose, ammonium sulpha or mixture thereof and present in the range of 0.1-45 % by weight of the composition.

[0218] Examples of biocide or anti-microbial / anti-bacterial agent(s), agent(s) used herein include but not limited to the group comprising of 1, 2,- Benzisothiazolin -3-one, blends of 1,2-benzisothiazolin-3-one and 2-methyl-4-isothiazolin-3-one, 5-chloro-2-methyl-4-isothiazolin-3-one, blends of 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one, zinc 1 -hydroxy -2(1H)-pyridinethione, blends of zinc l-hydroxy-2(lH)-pyridinethione and zinc oxide, and 2-n-octyl-4-isothiazolin-3-one or mixture thereof and present in the range of 0.001 to 10 % by weight of the composition.

[0219] Examples of the rheology modifier or thickeners or thickening agents or suspending agent(s)used herein include but not limited to the group comprising of polysaccharides, carboxymethylcellulose, bentonite clay, aluminium magnesium silicate, hydroxy propyl cellulose, Sodium methyl cellulose, xanthan gum, gum arabic, Silica powder, gaur gum, carbomer, chitosan, precipitated silica or mixtures thereof and present in the range of 0.001-5.0 % by weight of the composition. Examples of emulsifier(s) used herein include but not limited to the group comprising of araliphatic or aliphatic non-ionic oil emulsifier-ethoxylated sorbitol hexaester derived from oleic acid, emulsifier such as ethoxylated mono-, di- and trialkylphenols, ethoxylates of long-chain alcohols and polyethylene oxide / polypropylene oxide homo- and copolymers, Anionic and nonionic blend of castor oil ethoxylate, Hydrophobically Modified Polyacrylate Copolymer, Polymeric emulsifier (Nonionic poly alkylene oxide block copolymer), Ethoxylates of long -chain alkanols, Castor oil ethoxylate, ethoxylated monoalkylphenol, ethoxilates of cetyl alcohol and / or stearyl alcohol; water soluble emulsifier, Emulsifier (Blend of Anionic and Non-ionic), Tristyrylphenol ethoxylate-20 mole, Alkyl diphenyl sulfonates, Ethoxylated Tristyrylphenol,and Anionic emulsifier such as alkali metal and ammonium salts of alkyl sulfates, of hemisulfates of ethoxylated alkanols and ethoxylated alkylphenols, alkylsulfonic acids, bis(phenylsulfonic acid) ethers and their alkali metal or ammonium salts, sodiumlaurylsulfate, sodium (cetyl / stearyl) sulfate or mixture thereof and present in the range of 0.001-20 % by weight of the composition.

[0220] Examples of emulsifier(s) used herein is / are selected from group or non-ionic, ionic, or a blend or combination thereof, present in the range of 0.001-20 % by weight of the composition.

[0221] Examples of Non-ionic emulsifier(s) used herein is / are selected from group comprising of Araliphatic or aliphatic non-ionic oil emulsifier - ethoxylated sorbitol hexa-ester derived from oleic acid, Ethoxylated mono-, di- and trialkylphenols, Ethoxylates of long-chain alcohols, Polyethylene oxide / polypropylene oxide homo- and copolymers, Hydrophobically Modified Polyacrylate Copolymer (nonionic polymeric dispersant), Polymeric emulsifier (Nonionic polyalkylene oxide block copolymer), Ethoxylates of long-chain alkanols, Castor oil ethoxylate, Ethoxylated monoalkylphenol, Ethoxylates of cetyl alcohol and / or stearyl alcohol, Tristyrylphenol ethoxylate, Ethoxylated Tristyrylphenol, Non-ionic water-soluble emulsifiers, or a combination thereof.

[0222] Examples of the ionic emulsifier(s) used herein is / are selected from group comprising of alkali metal and ammonium salts of alkyl sulfates, hemisulfates of ethoxylated alkanols, hemisulfatesof ethoxylated alkylphenols, alkylsulfonic acids, bis(phenylsulfonic acid) ethers and their alkali metal or ammonium salts, sodium lauryl sulfate, sodium (cetyl / stearyl) sulfate, Ionic water-soluble emulsifiers or combination thereof.

[0223] Examples of solvent(s) and co-solvent(s) used herein include but not limited to the compounds selected from polar and non-polar solvent from the group comprising heavy aromatic hydrocarbon, diethyl phthalate, N-Methyl-2 -pyrrolidone (NMP), Solvent Naphtha (Solvent C-9), Di methyl sulfoxide (DMSO), Dimethylformamide (DMF), Dialkylene glycol dialkyl ethers, Methyl soyate oil, N- alcohol, 2-ethyl hexanol, alkyl amide, vegetable oil, mineral oil, distilled water, aromatic solvents, water or mixtures thereof and present in the range of 0.01 to 20% by weight of the composition.

[0224] Examples of colouring pigment(s) / dye(s) used herein include but not limited to the red dye FGR03, Permanent Rubin L5-B-01, pigment blue 15:4, pigment blue 15:3, pigment blue 15:2, pigment blue 15:1, pigment blue 80, pigment yellow 1, pigment yellow 13, pigment red 112, pigment red 48:2, pigment red 48: 1, pigment red 57: 1, pigment red 53:1, pigment orange 43, pigment orange 34, pigment orange 5, pigment green 36, pigment green 7, pigment white 6, pigment brown 25, basic violet 10, basic violet 49, violet 23, acid red 51, acid red 52, acid red 14, acid blue 9, acid yellow 23, basic red 10, basic red 108 or mixtures thereof and present in the range of 0.001- 10.0 % by weight of the composition.

[0225] Examples of polymer(s) used herein include but not limited to the isocyanate, polyisocyanate used is toluene-2, 4-diisocyanate (TDI), diethylenetriamine (DETA), ethylene diamine (EDA), triethylenetetramine (TETA), and / or hexamethylene diamine (HMDA), diethanolglycine sodium salt, ethanoldiglycine disodium salt, hydroxymonocarboxylic acid compounds, hydroxydicarboxylic acid compounds, tetrasodium N, N-bis(carboxylatomethyl)-L-glutamate (GLDA), methylene diisocyanate (MDI), and / or low molecular weight polydiisocynates or mixtures thereof and present in the range of 0.01- 5.0 % by weight of the composition.

[0226] Examples of binder(s) used herein include but not limited to the group of compounds selected from polyvinylpyrrolidone (PVP), polyvinyl alcohol, methyl cellulose, and carboxymethyl cellulose,sodium starch glycolate, polyisocyanate, polyterpene resin or mixtures thereof and present in the range of 0.01- 40 % by weight of the composition

[0227] Examples of the preservative(s) used herein include but not limited to the group of compounds selected from Methyl paraben (Methyl p-hydroxybenzoate), Propyl paraben (Propyl p-hydroxybenzoate), Methylisothiazolinone (MIT), Chloromethylisothiazolinone (CMIT), Benzisothiazolinone (BIT), DMDM Hydantoin, Imidazolidinyl Urea, Phenol, Cresol, Chlorocresol, Benzoic acid, Sorbic acid, Salicylic acid, Thymol (natural preservative), Sodium benzoate, Potassium sorbate, Bronopol (2-bromo-2-nitropropane-l,3-diol), Propyl para-hydroxy -benzoate or mixture thereof and present in the range of 0.01- 35 % by weight of the composition. Examples of stabilizer(s) used herein include but not limited to the compounds selected from butylated copolymer, Butylated Hydroxy Toluene (BHT), Butylated Hydroxyanisole (BHA), Ascorbic Acid (Vitamin C), Tocopherol (Vitamin E), Benzophenone-3 (a benzotriazole UV absorber), Hindered Amine Light Stabilizers (HALS), Propylene Glycol, Oxanilide derivatives, Ethoxylated Alkylphenols (e.g., nonylphenol ethoxylates), Block copolymers, Polyvinyl alcohol (PVA), Acrylic or Butylated Copolymers, Citric acid / Sodium citrate, Phosphates (e.g., Sodium or Potassium phosphate), Acetates (e.g., Sodium acetate), EDTA (Ethylenediaminetetraacetic acid), Citric acid (dual role: pH and chelation), NTA (Nitrilotriacetic acid), Xanthan gum, Attapulgite clay, Bentonite, Hydroxypropyl methylcellulose (HPMC) or mixture and present in the range of 0.01- 35 % by weight of the composition.

[0228] Examples of the pH adjusting agent(s) / buffering agent(s) used herein include but not limited to the compounds selected from Citric Acid, Citric Acid Monohydrate, Citric Acid Dihydrate, Sodium Citrate, Potassium Citrate, Tartaric Acid, Potassium Hydrogen Tartrate, Lactic Acid, Sodium Phosphate (Monobasic or Dibasic), Potassium Phosphate (Monobasic / Dibasic), Sodium Bicarbonate, Sodium Carbonate, Ammonium Acetate / Ammonium Hydroxide, Acetic Acid, Sodium Acetate, Borax (Sodium Borate) or mixture thereof and present in the range of 0.01- 25 % by weight of the composition.

[0229] According to the embodiments of the present invention, the present stable synergistic fungicidal composition can be formulated as one or more of Capsule suspension (CS), Dispersibleconcentrate (DC), Dustable powder (DP), Powder for dry seed treatment (DS), Emulsifiable concentrate (EC), Emulsifiable granule (EG), Emulsion water-in-oil (EO), Emulsifiable powder (EP), Emulsion for seed treatment (ES), Emulsion oil-in-water (EW), Flowable concentrate for seed treatment (FS), Granules (GR), Micro-emulsion (ME), Oil-dispersion (OD), Oil miscible flowable concentrate (OF), Oil miscible liquid (OL), Oil dispersible powder (OP), Suspension concentrate (SC), Suspension concentrate for direct application (SD), Suspo -emulsion (SE), Water soluble granule (SG), Soluble concentrate (SL), Spreading oil (SO), Water soluble powder (SP), Water soluble tablet (ST), Ultra-low volume (ULV) suspension, Tablet (TB), Ultra-low volume (ULV) liquid, Water dispersible granules (WG), Wettable powder (WP), Water dispersible powder for slurry seed treatment (WS), Water dispersible tablet (WT), a mixed formulation of CS and SC (ZC) or a mixed formulation of CS and SE (ZE) or a mixed formulation of CS and EW (ZW). According to the embodimentsof the present invention, the invention further provides the process for preparation of the said fungicidal composition, wherein the said composition can be one or more of Capsule suspension (CS), Dispersible concentrate (DC), Dustable powder (DP), Powder for dry seed treatment (DS), Emulsifiable concentrate (EC), Emulsifiable granule (EG), Emulsion water-in-oil (EO), Emulsifiable powder (EP), Emulsion for seed treatment (ES), Emulsion oil-in-water (EW), Flowable concentrate for seed treatment (FS), Granules (GR), Micro-emulsion (ME), Oil-dispersion (OD), Oil miscible flowable concentrate (OF), Oil miscible liquid (OL), Oil dispersible powder (OP), Suspension concentrate (SC), Suspension concentrate for direct application (SD), Suspo-emulsion (SE), Water soluble granule (SG), Soluble concentrate (SL), Spreading oil (SO), Water soluble powder (SP), Water soluble tablet (ST), Ultra-low volume (ULV) suspension, Tablet (TB), Ultra-low volume (ULV) liquid, Water dispersible granules (WG), Wettable powder (WP), Water dispersible powder for slurry seed treatment (WS), Water dispersible tablet (WT), a mixed formulation of CS and SC (ZC) or a mixed formulation of CS and SE (ZE) or a mixed formulation of CS and EW (ZW).

[0230] In further embodiment of the present invention, depending on the formulation type, they comprise one or more liquid or solid carriers, appropriate surfactants (such as dispersants, protective colloids, emulsifiers, wetting agents and tackifiers), and appropriate further excipients which are customary for formulating fungicidal composition. Further excipients include e.g., organic andinorganic thickeners, bactericides, antifreeze agents, antifoams, colorants and, for seed formulations, adhesives.

[0231] In one of the embodiments of the present invention, suitable carriers include liquid and solid carriers. Liquid carriers include e.g. non-aqueous solvents such as cyclic and aromatic hydrocarbons, e.g. paraffins, tetrahydronaphthalene, alkylated naphthalenes and their derivatives, alkylated benzenes and their derivatives, alcohols such as methanol, ethanol, propanol,butanol and cyclohexanol, ketones such as cyclohexanone, strongly polar solvents, e.g. amines such as N-methylpyrrolidone, and water as well as mixtures thereof. Solid carriers include e.g. mineral earths such as silicas, silica gels, silicates, talc, kaolin, limestone, lime, chalk, bole, loess, clay, dolomite, diatomaceous earth, calcium sulfate, magnesium sulfate, magnesium oxide, ground synthetic materials, fertilizers such as ammonium sulfate, ammonium phosphate, ammonium nitrate, ureas, and products of vegetable origin such as cereal meal, tree bark meal, wood meal and nutshell meal, cellulose powders, or other solid carriers.

[0232] In one embodiment, additives such as Siloxane Polyalkyleneoxide Copolymer or Siloxane Polyalkyleneoxide Copolymer super-wetter is an organosilicone based powder adjuvant that can enhance the water absorption efficiency of hard-to-wet soils by increasing their water infiltration, drainage, water retention and hydrophilicity; tallow amine ethoxylate increases the biocompatibility in environmental applications and help in the interactions of active ingredients; ammonium sulphate help is resistant to leaching and helps the crop to utilize nitrogen efficiently; urea clathrate provides superior wetting and spray retention properties and serves as an excellent nitrogen source for crops and epoxide soybean oil provides increased active ingredient uptake and improved rain fastness to the composition; and epoxide soybean oil provides increased active ingredient uptake and improved rain fastness to the composition. The said additives are stable and hygroscopic resulting in an efficient uptake and functioning. In one embodiment, additives such as urea clathrate, Siloxane Polyalkyleneoxide Copolymer or Siloxane Polyalkyleneoxide Copolymer super-wetter, tallow amine ethoxylate, ammonium sulphate, and epoxide soybean oil either alone or in combination thereof, present in the range of 0.001 - 20% by weight of the composition.In one embodiment of the present invention, Siloxane Polyalkyleneoxide Copolymer has superspreading ability, it significantly lowers the surface tension of spray solutions, allowing them to spread uniformly across plant surfaces, including waxy or hard-to-wet leaves. This enhances the penetration and absorption of fungicides, leading to improved efficacy. Siloxane Polyalkyleneoxide Copolymer is especially effective in low-volume spray applications and helps increase rainfastness and reduce runoff. Its use supports more efficient fungicides delivery, often allowing for reduced application rates.

[0233] In one embodiment of the present invention, the inclusion of both Siloxane Polyalkyleneoxide Copolymer super-wetter and tallow amine ethoxylate in a formulation significantly enhances its surface activity and delivery efficiency. Siloxane Polyalkyleneoxide Copolymer, a trisiloxane-based super-spreader, dramatically reduces surface tension, enabling rapid and uniform spreading of the solution across plant surfaces, even on waxy or water-repellent leaves. In synergy, tallow amine ethoxylate, a non-ionic surfactant, acts as a powerful wetting and penetration agent, improving the absorption of active ingredients into plant tissues. This combination ensures maximum bioavailability and performance of fungicidal actives.

[0234] In one embodiment of the present invention, ammonium sulphate particularly as a water conditioner and adjuvant. It helps improve the efficacy of fungicides, by binding with hard water cations such as calcium and magnesium that would otherwise reduce fungicides absorption and activity. By preventing these ions from interacting with the active ingredient, ammonium sulphate enhances uptake into plant tissues. It may also act as a nitrogen source, supporting plant growth. In one embodiment of the present invention, Epoxide soybean oil, a bio-based plasticizer and solvent, improves formulation compatibility, reduces phytotoxicity, and enhances the dispersion of active compounds. Derived from renewable sources, both additives support sustainable agriculture by offering low toxicity, biodegradability, and improved formulation efficiency without compromising efficacy.

[0235] In one embodiment of the present invention, Siloxane Polyalkyleneoxide Copolymer, tallow amine ethoxylate, ammonium sulphate, and epoxide soybean oil are additives used individually or in combination to enhance the performance of fungicidal formulations. Siloxane Polyalkyleneoxide Copolymer, a superspreading organosilicone surfactant, reduces surface tension and improves leaf coverage and penetration of active ingredients. Tallow amine ethoxylates, as non-ionic surfactants,aid in emulsification and enhance fungicide uptake. Ammonium sulphate serves as a water conditioner, preventing hard water ions from reducing fungicidal efficacy, while also acting as a nitrogen source. Epoxide soybean oil, a biodegradable solvent and plasticizer, improves formulation stability, compatibility, and reduces phytotoxicity. Used alone or synergistically, these additives optimize spray performance, improve bioavailability of actives, and support sustainable and effective crop protection.

[0236] In one embodiment, additives such as urea clathrate, Siloxane Polyalkyleneoxide Copolymer or Siloxane Polyalkyleneoxide Copolymer super-wetter, tallow amine ethoxylate, ammonium sulphate, organic compounds, and epoxide soybean oil either alone or in combination thereof, present in the range of 0.01 - 20% by weight of the composition.

[0237] According to the embodiments of the present invention, the present stable synergistic fungicidal composition can be applied to various crops and plants including but not limited to Tomato, Potato, Apple, Wheat, Maize, Paddy (Rice), Jowar, Chilies, Cauliflower, Groundnut, Grapes, Guava, Banana, Cumin, Groundnut, Chickpea, Onion, Soybean, Black gram, Cabbage, Rice, Coffee, Table grapes, Perennial and annual crops, Turf, Landscape ornamentals, Fruit trees, Vines, Sunflowers, Ornamental shrubs including roses, Cereals including barley, oat, rye; Peanuts; Vegetables including onions, peas, pepper; Sugarcane, etc.

[0238] According to the embodiments of the present invention, the present stable synergistic fungicidal composition provides synergistic and effective control against wide range of fungi including Scab, Powdery mildew, Leafspot, Dieback, Early blight& Late blight, Premature leaf fall, Alternaria spot / blight, sooty blotch, Brown& black rust, Blight, Leaf blight, Downy mildew, Blight, Loose smut, Flag smut, Collar rot, Root rot, Stem rot, Wilt, Root rot, flag smut, Fruit rot, Tikka& rust, Blast, Sheath blight, Purple blotch, Anthracnose (pod blight), Leaf spot, Anthracnose, Yellow rust and powdery, Purple blotch, Alternaria leaf spot, Stemphylium blight, Sheath Blight, Tikka leaf spot, Cercospora leaf spot, Leaf spot (Alternaria, Cercospora & Myrothecium), Leaf rust, Dollar spot, Summer patch, Brown patch, Potato blight, Smut, Bunt, Stripe rust, Yellow leaf spot, Powdery mildew, Scelerotinia rot, Black spot, Net blotch, etc.According to the embodiments, the stable synergistic fungicidal composition according to the invention can be applied to any and all developmental stages of fungi. In yet another embodiment, the present stable synergistic fungicidal composition of the present invention can be applied to a plant / crop / soil by spraying, rubbing, atomizing, irrigating, evaporating, dusting, fogging, broadcasting, pouring, mist blowing, soil mixing, foaming, painting, spreading-on, drenching, dipping or drip irrigation, etc.

[0239] In yet another embodiment, the fungicidal composition of the present invention can also comprise or may be applied together and / or sequentially with further active compounds. These further compounds can be selected from fertilizers or micronutrient donors or microorganisms or other preparations that influence plant growth, such as inoculants (e.g., a strain of nitrogen -fixing bacteria), and plant inducers. Through the fungicidal composition of present invention, the number of applications to control wide range of fungi appearing at the same time is minimised. The composition of present invention is highly safe to the user and to the environment. The composition offers the user a single homogenous application eliminating the need for tank mix. The composition also is cost-effective as it provides much greater simultaneous control and can be used in a variety of crops with a broader spectrum of protection.

[0240] The stable synergistic fungicidal composition of the present invention exhibits highly advantageous curative, preventive, and systemic fungicidal properties for protecting plants and crops against fungal pathogens and fungal diseases.

[0241] The composition of the present invention provides control of fungal diseases either preventatively or curatively by applying an effective amount of the composition prior to infection or after the onset of fungal infection.

[0242] Thus, before describing the present invention in detail, it is to be understood that this invention is not limited to the particularly exemplified systems or process parameters, which may of course vary. It is also to be understood that the terminology used herein is for the purpose of describing particular embodiments of the invention only and is not intended to limit the scope of the invention in any manner. The use of examples anywhere in this specification, including examples of any terms discussed herein, is illustrative only and in no way limits the scope and meaning of the invention or of any exemplified term. Likewise, the invention is not limited to the variousembodiments described in this specification. Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by a person of ordinary skill in the art to which this invention pertains. In the event of any conflict, the present document, including definitions, shall control.

[0243] In one embodiment, the composition according to the present invention acts synergistically to control fungal pathogens and associated diseases in various crops.

[0244] Representative examples of the present fungicidal compositions of this invention are provided below and are not to be construed as limiting in any manner.

[0245] EXAMPLES: GENERAL RECIPE OF COMPOSITION OF PRESENT INVENTION:

[0246] % (w / w) of S. No. Ingredients the composition Myclobutanil or its agrochemically acceptable salts, esters and

[0247] 1 0.001-90 derivatives Technical

[0248] Mancozeb or its agrochemically acceptable salts, esters and derivatives

[0249] 2 0.001-90 Technical

[0250] Tebuconazole or its agrochemically acceptable salts, esters or its

[0251] 3 0.001-90 derivatives Technical

[0252] Additive(s)- Siloxane Polyalkyleneoxide Copolymer, tallow amine

[0253] 4 ethoxylate, ammonium sulphate, and Epoxide soybean oil either alone or 0.01-20 in combination thereof

[0254] Surfactant / Dispersing agent(s) / Co-dispersant(s)- polymeric anionic dispersant, polyarylphenyl ether phosphate, tristyryl phenol ethoxylate, Polymethyl methacrylate -polyethylene glycol graft copolymer, acrylate

[0255] 5 0.01-20 copolymer, acrylic copolymer, polymeric dispersant, Calcium salt of

[0256] alkyl benzene sulphonate, Non-ionic surfactant, polyalkoxylated butyl

[0257] ether, acrylic graft copolymer, Sodium lauryl sulphonate, Sodium

[0258]

[0259] methyl oleoyl taurate, non-ionic proprietary surfactant, Polymeric anionic dispersing agent, Methyl naphthalene sulfonic acid, polymer with formaldehyde, sodium salt, ethoxylated tristryl phenol Sulphate, alkyl naphthalene formaldehyde condensate, naphthalene sulfonic acid, phenol sulfonic acid-formaldehyde polycondensation as sodium salt, sodium salt condensate with formaldehyde, ethoxylated oleyl cetyl alcohol, Sodium Alkyl Naphthalene Sulfonate Blend, styrenated phenol ethoxylate, polyalkelene glycol ether, Sodium Isopropyl Naphthalene Sulfonate, Dialkyl naphthalene sulphonate sodium salt, Naphthalene Sulphonic Acid, Formaldehyde, Acrylate graft Copolymer, Ethoxylated fatty glyceride, Ethoxylated Polyarylphenol Phosphate Ester, Lignosulfonic Acid, Sodium Salt, Sulfomethylated, ethoxylated fatty alcohol, methyl naphthalene sulfonic acid, polymer with formaldehyde sodium salt, Sodium Alkylnaphthalene Sulfonate Formaldehyde Condensate, Sodium polymethyl methacrylate, sodium polyacrylate, alkyl naphthalene sulfonate formaldehyde condensate or its sodium salt, Sodium Polycarboxylate, Sodium Naphthalene Sulfonate formaldehyde condensate, sodium lignosulphonate, calcium lignosulphonate, Sodium Alkyl Naphthalene Sulfonate, Naphthalene Sulphonic Acid, Formaldehyde, alkylphenol polyoxyethylene ether, sodium salt of naphthalene sulfonate condensate, alkyl naphthalene sulfonate condensate blend, polymeric surfactant, sodium salt of alkyl naphthalene sulfonate, sodium salt of methyl naphthalene sulfonate, polycarboxylate, naphthalene sulfonic acid-branched and linear derivative sodium salts, fatty alcohol polyoxyethylene ether, alcohol polyglycol ether, nonaqueous dispersant - non-ionic polymeric surfactant, aqueous dispersant

[0260] - polymeric amphoteric aqueous dispersant, Graft Comb copolymer or mixtures thereof

[0261] Wetting agent(s)- tristyrylphenol ethoxylate non-ionic emulsifier, polyalkoxylated butyl ether, mixture of non-ionic surfactants, Blend of 0.001-20 Anionic and Non-ionic, alkoxylated alcohol, block copolymer, alcohol

[0262]

[0263] polyglycol ether, alkyl olefin sulphates, dioctyl sulpho succinate, alkyl naphthalene sulphate, Di-isopropyl Napthalene sulphonate, Sodium alkyl naphthalene sulfonate formaldehyde condensate, Benzenesulfonic acid, Hydroxy polymer with formaldehyde, Phenol and Urea sodium salt, Polyalkoxy ethers, alkyl phenol ethoxylates, tri-styrenated phenol ethoxylate, EO / PO block co-polymers, Polymeric emulsifier (Nonionic polyalkylene oxide block copolymer), butyl polyalkylene oxide block copolymer, sodium lauryl sulphate, Alpha olefin sulphonate, sodium sulphates or mixtures thereof

[0264] Defoamer / Anti-foaming agent- silicon emulsion based anti-foam agents, Siloxane polyalkyleneoxide, Polydimethylsiloxane, trisiloxane ethoxylates, silicone oil, silicone compound, C10~C20 saturated fat acid 0.001-5.0 compounds or C8~C10 aliphatic alcohols compound, vegetable oil based antifoam, tallow based fatty acids, polyalkyleneoxide -modified polydimethylsiloxane emulsion and mixtures thereof

[0265] Anti-freezing agent(s)- glycol, propylene glycol, mono ethylene glycol, glycerine, diethylene glycol, sorbitol, urea, mannitol, polyethylene glycol 0.01-20 or mixtures thereof

[0266] Filler(s)- silicon dioxide, china-clay, kaolin, starch, bentonite, precipitated silica, fumed silica, lactose monohydrate, talcum powder, lactose, ammonium sulphate, water, sodium Sulphate, magnesium 0.001-60 sulphate, sodium citrate, sodium chloride, potassium chloride and mixtures thereof

[0267] Anti-caking agent(s)- group of talc, hydrous magnesium silicate, magnesium carbonate, calcium carbonate, precipitate silica, silica 0.001-10 powder, hydrophobic fumed silica and mixtures thereof

[0268] Carrier(s)- silicon dioxide, china clay, kaolin, starch, bentonite,

[0269] 0.1-45 precipitated silica, silica powder, fumed silica, ppt silica powder, lactose

[0270]

[0271] monohydrate, talcum powder, lactose, Methylated soyabean oil, ammonium sulpha or mixture thereof

[0272] Biocide / Anti-microbial agent (s)- 1, 2,- Benzisothiazolin -3-one, blends of l,2-benzisothiazolin-3-one and 2-methyl-4-isothiazolin-3-one, 5- chloro-2-methyl-4-isothiazolin-3-one, blends of 5-chloro-2-methyl-4- 0.001-10 isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one, zinc 1 -hydroxy - 2(lH)-pyridinethione, blends of zinc l-hydroxy-2(lH)-pyridinethione and zinc oxide, and 2-n-octyl-4- isothiazolin-3-one or mixture thereof Rheology modifier / Thickening agent(s)- polysaccharides, carboxymethyl cellulose, bentonite clay, aluminium magnesium silicate,

[0273] 0.001-5.0 hydroxy propyl cellulose, xanthan gum, gum arabic, Silica powder, gaur gum, carbomer, chitosan, precipitated silica or mixtures thereof Emulsifier(s)- Non-ionic emulsifiers- Araliphatic or aliphatic non-ionic oil emulsifier - ethoxylated sorbitol hexaester (derived from oleic acid), Ethoxylated mono-, di- and trialkylphenols, Ethoxylates of long-chain alcohols, Polyethylene oxide / polypropylene oxide homo- and copolymers, EO / PO block copolymers, Polymeric emulsifier (Nonionic polyalkylene oxide block copolymer), Ethoxylates of long-chain alkanols, Castor oil ethoxylate, Ethoxylated monoalkylphenol, Ethoxylates of cetyl alcohol and / or stearyl alcohol, Tristyrylphenol 0.001-20 ethoxylate, Ethoxylated Tristyrylphenol or a mixture thereof.

[0274] Ionic emulsifiers including but not limited to Alkali metal and ammonium salts of alkyl sulfates, Hemisulfates of ethoxylated alkanols and ethoxylated alkylphenols, Alkylsulfonic acids, Bis(phenylsulfonic acid) ethers and their alkali metal or ammonium salts, Sodium lauryl sulfate, Sodium (cetyl / stearyl) sulfate, or a mixture thereof.

[0275] Or a mixture of ionic or non-ionic.

[0276]

[0277] Solvent or co-solvent(s) - polar and non-polar solvent from the group comprising heavy aromatic hydrocarbon, N methyl pyrollidone (NMP), Solvent Naphtha (Solvent C-9), Di methyl sulfoxide (DMSO),

[0278] 0.01-20 Dimethylformamide (DMF), Propylene Glycol, N- alcohol, 2-ethyl hexanol, alkyl amide, vegetable oil, mineral oil, distilled water, aromatic solvents, water or mixtures thereof

[0279] Colouring pigment(s) / dye(s)- red dye FGR03, Permanent Rubin L5-B- 01, pigment blue 15:4, pigment blue 15:3, pigment blue 15:2, pigment blue 15:1, pigment blue 80, pigment yellow 1, pigment yellow 13, pigment red 112, pigment red 48:2, pigment red 48: 1, pigment red 57: 1

[0280] , pigment red 53:1, pigment orange 43, pigment orange 34, pigment 0.001-10 orange 5, pigment green 36, pigment green 7, pigment white 6, pigment brown 25, basic violet 10, basic violet 49, violet 23, acid red 51, acid red

[0281] 52, acid red 14, acid blue 9, acid yellow 23, basic red 10, basic red 108 or mixtures thereof

[0282] Polymer(s)- isocyanate, polyisocyanate used is toluene -2, 4-diisocyanate (TDI), diethylenetriamine (DETA), ethylene diamine (EDA), triethylenetetramine (TETA), and / or hexamethylene diamine (HMDA), diethanolglycine sodium salt, ethanoldiglycine disodium salt,

[0283] 0.01-5.0 hydroxymonocarboxylic acid compounds, hydroxydicarboxylic acid compounds, tetrasodium N, N-bis(carboxylatomethyl)-L-glutamate (GLDA), Graft Comb copolymer, methylene diisocyanate (MDI), and / or low molecular weight polydiisocynates or mixtures thereof

[0284] Binder(s)- polyvinylpyrrolidone, polyvinyl alcohol, methyl cellulose, and carboxymethyl cellulose, polyisocyanate, polyterpene resin or 0.01-40 % mixtures thereof

[0285] Preservative(s)- Methyl paraben (Methyl p-hydroxybenzoate), Propyl paraben (Propyl p-hydroxybenzoate), Methylisothiazolinone (MIT), 0.01-35% Chloromethylisothiazolinone (CMIT), Benzisothiazolinone (BIT),

[0286]

[0287] DMDM Hydantoin, Imidazolidinyl Urea, Phenol, Cresol, Chlorocresol, Benzoic acid, Sorbic acid, Salicylic acid, Thymol (natural preservative), Sodium benzoate, Potassium sorbate, Bronopol (2-bromo-2- nitropropane-l,3-diol), Propyl para-hydroxy -benzoate or mixture thereof Stablizer(s)- butylated copolymer, Butylated Hydroxy Toluene (BHT), Butylated Hydroxyanisole (BHA), Ascorbic Acid (Vitamin C), Tocopherol (Vitamin E), a benzotriazole UV absorber, Hindered Amine Light Stabilizers (HALS), Oxanilide derivatives, Ethoxylated Alkylphenols (e.g., nonylphenol ethoxylates), Block copolymers (e.g.,

[0288] 20 Pluronic types), Polyvinyl alcohol (PVA), Acrylic or Butylated 0.01-35% Copolymers, Citric acid / Sodium citrate, Phosphates (e.g., Sodium or Potassium phosphate), Acetates (e.g., Sodium acetate), EDTA (Ethylenediamine tetraacetic acid), Citric acid (dual role: pH and chelation), NTA (Nitrilotriacetic acid), Xanthan gum, Attapulgite clay, Bentonite, Hydroxypropyl methylcellulose (HPMC) or mixture thereof

[0289] pH adjusting agent(s) / Buffering agent(s) - Citric Acid, Citric Acid Monohydrate, Citric Acid Dihydrate, Sodium Citrate, Potassium Citrate, Tartaric Acid, Potassium Hydrogen Tartrate, Lactic Acid, Sodium

[0290] 21 Phosphate (Monobasic or Dibasic), Potassium Phosphate (Monobasic / 0.01-25% Dibasic), Sodium Bicarbonate, Sodium Carbonate, Ammonium Acetate

[0291] / Ammonium Hydroxide, Acetic Acid, Sodium Acetate, Borax (Sodium Borate) or mixture thereof

[0292] 22 Distilled water / China Clay / DMF QS Total 100

[0293]

[0294] EXAMPLE A. Myclobutanil 0.64% + Tebuconazole 8 % + Mancozeb 48% SC

[0295] Sr. Concentration / % w / w) Ingredients

[0296] No. or % w / v

[0297]

[0298] 1 Myclobutanil Technical 0.64 %

[0299] 2 Tebuconazole Technical 8 %

[0300] 3 Mancozeb Technical 48 %

[0301] 4 Acrylic graft copolymer 5.0%

[0302] 5 Epoxide Soybean Oil 0.5%

[0303] 6 Propylene Glycol 5%

[0304] 7 Ethoxylated Fatty Alcohol 2.0%

[0305] Polyalkyleneoxide-modified

[0306] 8

[0307] Polydimethylsiloxane 1.0%

[0308] 9 l,2-Benzisothiazolin-3-one 0.2%

[0309] 10 Xanthum gum 0.2%

[0310] 11 Distilled Water Q. S. to make 100%

[0311] Total 100.0

[0312]

[0313] FORMULATION PROCESS

[0314] 1. DM water and mixture of surfactants (Acrylic graft copolymer, Ethoxylated Fatty Alcohol), Epoxide Soybean Oil, Polyalkyleneoxide-modified Polydimethylsiloxane emulsion & Propylene Glycol (PG) were charged and further diluted in required D. M. Water.

[0315] 2. The required technicals i.e., Myclobutanil Technical, Tebuconazole Technical, Mancozeb Technical, were then mixed to obtain homogeneous mass by high shearing.

[0316] 3. The above mixed mass was ground in bead Mill. Grinding was carried out until a mean particle size of below 5 microns was obtained.

[0317] 4. A 2% gum solution was prepared by taking 100 g DM water and 0.2 g of l,2-Benzisothiazolin-3- one, and then under slow stirring, 2 g xanthan gum was added.

[0318] 5. After the grinding, 2% water solution of xanthan gum was added under low stirring and mixed until a homogeneous mixture was obtained

[0319] 6. Finally, the quality parameters were checked.

[0320] STABILITY DATA: Myclobutanil 0.64% + Tebuconazole 8 % + Mancozeb 48% SC

[0321] Sr. Test Parameter Specification Observation HST at 54 Cold Test No °C 14 days at 0°C

[0322] 7days

[0323]

[0324] Description White to off Complies Complies Complies white coloured

[0325] suspension liquid

[0326] free from

[0327] extraneous matter

[0328] Myclobutanil Technical

[0329] 0.64 % (+ 10%, - (%w / w) 0.70 0.69 0.68

[0330] 5%)

[0331] Tebuconazole 8 % (+ 10%, - 5%) 8.32 8.22 8.51 Technical (% w / w)

[0332] Mancozeb technical (%

[0333] 48 % (+5%, -5%) 48.78 48.54 49.24 w / w))

[0334] Suspensibility of Min 80% 92.44 92.71 92.41 Myclobutanil (% w / w)

[0335] Suspensibility of Min 80% 92.31 92.54 92.28 Tebuconazole (% w / w)

[0336] Suspensibility of Min 80% 92.36 92.81 92.35 Manzcozeb(% w / w)

[0337] Spontaneity of Min 80% 91.03 91.72 91.01 dispersion

[0338] Myclobutanil (% w / w)

[0339] Spontaneity of Min 80% 91.32 91.56 91.28 dispersion

[0340] Tebuconazole (% w / w)

[0341] Spontaneity of Min 80% 91.08 91.84 91.02 dispersion Mancozeb

[0342] (% w / w)

[0343] pH 1.0% Aqueous 5.0 to 8.0 6.56 6.63 6.62 Solution

[0344] Viscosity @25°C 350 to 700 451 432 458 Spindle 63 60 rpm

[0345] (CPS)

[0346]

[0347] 13 Wet Sieve, material Min 98 % 99.13 99.23 99.11 passing through 45

[0348] micron sieve

[0349] 14 Persistent foam after 80ml Max 17 13 15

[0350] Imin (ml)

[0351] 15 Pourability (Rinse Max 2.0 0.39 0.22 0.42

[0352] residue)

[0353]

[0354] EXAMPLE B: Myclobutanil 0.64% + Tebuconazole 8 % + Mancozeb 48% WP

[0355] Sr. Ingredients % W / W or % W / V No.

[0356] 1 Myclobutanil Technical 0.64 %

[0357] 2 Tebuconazole Technical 8 %

[0358] 3 Mancozeb Technical 48 %

[0359] 4 Sodium Lignosulphonate 10.0%

[0360] 5 Sodium alkyl naphthalene sulfonate formaldehyde condensate 5.0%

[0361] 6 Sodium lauryl sulphonate / Alpha olefin sulphonate 3.0%

[0362] 7 Silica ppt 2.0%

[0363] 8 China clay Q. S. to make 100 TOTAL 100.0

[0364]

[0365] MANUFACTURING PROCESS:

[0366] 1. All required technicals, i.e., Myclobutanil Technical, Tebuconazole Technical, Mancozeb Technical, and inert ingredients, were mixed and then ground in an air jet mill.

[0367] 2. The particle size was checked after grinding to ensure that it was less than 10 microns (D90). 3. The ground powder was post-blended and mixed well.

[0368] STABILITY DATA: Myclobutanil 0.64% + Tebuconazole 8 % + Mancozeb 48% WPSr. arameter Specification Observation at HST at 54 °C No. Room 14 days Temperature

[0369] 1 rance White to off white Complies Complies powder free from

[0370] extraneous matter

[0371] 2 Myclobutanil Technical

[0372] 0.64 % (+ 10%, -5%) 0.681 0.690 (%w / w)

[0373] 3 Tebuconazole technical (% 8 % (+ 10%, -5%)

[0374] 8.33 8.38 w / w))

[0375] 4 Mancozeb Technical (%

[0376] 48 % (+5%, -5%) 48.80 48.27 w / w)

[0377] 5 Suspensibility of Min 80% 92.33 92.56

[0378] Myclobutanil (% w / w)

[0379] 6 Suspensibility of Min 80% 92.38 92.81 Tebuconazole (% w / w)

[0380] 7 Suspensibility of Mancozeb Min 80% 92.12 92.23

[0381] (% w / w)

[0382] 8 Persistant Foaming, mL Max. 60 after 1 minute 11 14

[0383] (1% solution in 342 ppm

[0384] hard water)

[0385] 9 Wet Sieve, material Min 98 % 98.82 98.90

[0386] passing through 45- micron sieve

[0387] 10 pH of 1% aqueous 5.0 to 8.0 6.56 6.63

[0388] emulsion

[0389]

[0390] 11 Wettability 120 sec max 60 70 Example C: Myclobutanil 0.64% + Tebuconazole 8 % + Mancozeb 48% WG

[0391] Sr. No. Ingredients % W / W or % w / v

[0392] 1 Myclobutanil Technical 0.64 % 2 Tebuconazole Technical 8 %

[0393] 3 Mancozeb Technical 48 % 4 Sodium Isopropyl Naphthalene Sulfonate 2.5% 5 Sodium Lignosulphonate 4.0% 6 Sodium salt of naphthalene sulfonate formaldehyde condensate 4.5% 7 Sodium Polycarboxylate 3.0% 8 Lactose monohydrate 8.0%

[0394]

[0395] 9 Polydimethylsiloxane emulsion 0.5%10 Silica ppt 3.0% 11 China clay QS to make

[0396] 100%

[0397]

[0398] TOTAL | 100.0

[0399] MANUFACTURING PROCESS:

[0400] China clay was taken in the ribbon blender for mixing. To this, Silica ppt, Sodium Isopropyl Naphthalene Sulfonate, Sodium Lignosulphonate, Sodium salt of naphthalene sulfonate formaldehyde condensate, Sodium Polycarboxylate, Lactose monohydrate, Myclobutanil Technical, Tebuconazole Technical, Mancozeb Technical were added and mixed well.

[0401] Mixing was continued until the material became completely homogenized. The premix was then passed through the Airjet mill at 6 to 7 kg / cm2of grinding pressure and a feeding rate of 100 to 150 kg / hr so as to obtain a particle size of D90 less than 10 microns. The ground material was collected in the post blender.

[0402] Extrusion process

[0403] Into the post blender, the solution of water and Polydimethylsiloxane emulsion was added by means of spraying, and a dough was prepared. This dough was mixed well to obtain a well-hydrated mass for extrusion. The dough was then allowed to pass through the screw valve fitted with the post blender and subsequently passed through the basket extruder.

[0404] Drying Process

[0405] The wet extruded granules were passed through the VFBG (vibro fluid bed drier), which had been brought to a consistent temperature of 50 °C prior to drying. The granules were then checked for moisture content, which was required to be not more than 3%. Once the parameter was set, the process was continued.

[0406] The dried granules were passed through a vibro sieve machine to separate any lumps or dust, and the desired size granules were collected and packed.

[0407] STABILITY DATA: Myclobutanil 0.64% + Tebuconazole 8 % + Mancozeb 48% WG

[0408] Sr. arameter Specification Observation HST at 54

[0409] No. °C 14

[0410] days

[0411] 1 Appearance Off-white coloured Complies Complies

[0412]

[0413] powder free fromany lumps or

[0414] extraneous matter

[0415] 2 Myclobutanil

[0416] 0.693 0.702 Technical (%w / w) 0.64 % (+ 10%, -5%)

[0417] 3 Tebuconazole

[0418] 8 % (+ 10%, -5%) 8.34 8.57 technical (% w / w))

[0419] 4 Mancozeb Technical

[0420] 48 % (+5%, -5%) 48.81 48.28 (% w / w)

[0421] 5 Suspensibility of Min 80% 92.35 92.55 Myclobutanil (%

[0422] w / w)

[0423] 6 Suspensibility of Min 80% 92.36 92.82 Tebuconazole (%

[0424] w / w)

[0425] 7 Suspensibility of Min 80% 92.15 92.33 Mancozeb (% w / w)

[0426] 8 Wet Sieve test Min 98 % 99.39 99.45 (retained on 45

[0427] micron sieve, %w / w

[0428] 9 pH of 1% aqueous 5.0 to 8.0 6.57 6.64 emulsion

[0429] 10 Persistent foam after 60 Max 12 11

[0430] Imin (ml)

[0431]

[0432] 11 Wettability 120 sec Max 20 18

[0433] Example D: Myclobutanil 0.64% + Tebuconazole 8 % + Mancozeb 48% OD

[0434] Sr. No. Ingredients % W / W 1 Myclobutanil Technical 0.64 % 2 Tebuconazole Technical 8 % 3 Mancozeb Technical 48 % 4 Graft Comb copolymer 10.0% 5 Castor oil ethoxylate 4.5% 6 Ethoxylated Polyarylphenol Phosphate Ester 5.0% 7 Polypropylene glycol 2.0% 8 Polydimethylsiloxane emulsion 0.05% 9 Methylated soyabean oil Q. S.to make

[0435] 100%

[0436]

[0437] TOTAL 100.0

[0438]

[0439] Oil Dispersion (OD) formulation Process

[0440] 1. Added selected oil and dispersants / wetting agents were dissolved under stirring.

[0441] 2. Finely powdered / micronized active ingredients were slowly added with high-shear mixing.

[0442] 3. Mixed until the active was uniformly wetted and was dispersed in oil.

[0443] 4. Milled the dispersion (bead / ball / sand mill) to achieve required particle size.

[0444] 5. Required additives were added.

[0445] 6. Particle size, viscosity, suspensibility, stability were homogenized and checked.

[0446] 7. Filter if required and pack the finished OD formulation.

[0447] Stability data:

[0448] Sr. No. Test Parameter Specification Observation HST at 54 Cold Test at 0°C 7days 1 Appearance Off-white coloured Complies Complies Complies powder free from any

[0449] lumps or extraneous

[0450] matter

[0451] 2 Myclobutanil Technical 0.70 0.693 0.681

[0452] (%w / w) 0.64 % (+ 10%, -5%)

[0453] 3 Tebuconazole technical (%

[0454] 8 % (+ 10%, -5%) 8.34 8.21 8.57 w / w))

[0455] 4 Mancozeb Technical (%

[0456] 48 % (+5%, -5%) 48.81 48.28 48.56 w / w)

[0457] 5 Suspensibility of Min 80% 92.35 92.55 92.41

[0458] Myclobutanil (% w / w)

[0459] 6 Suspensibility of Min 80% 92.36 92.82 92.28

[0460] Tebuconazole (% w / w)

[0461] 7 Suspensibility of Min 80% 92.15 92.33 92.35

[0462] Mancozeb (% w / w)

[0463] 8 Dispersion Stability 0 h Initial Complies Complies Complies dispersion complete

[0464] 0.5 h " Cream",

[0465] maximum: 0.5 ml

[0466] Free oil",

[0467] maximum: trace

[0468] Sediment",

[0469] maximum: 0.1 ml

[0470]

[0471] 24 h Redispersion complete

[0472] 24.5 h " Cream",

[0473] maximum: 1 ml

[0474] " Free oil",

[0475] maximum: trace

[0476] " Sediment",

[0477] maximum: 0.25 ml

[0478] 9 Pourability Min 95% 98 99 97.5 10 Viscosity @25°C Spindle 350 to 700 451 432 458

[0479] 63 60 rpm (CPS)

[0480] 11 Persistent foam after Imin 60 Max 12ml 11ml 12ml

[0481]

[0482] (ml)

[0483] Evaluation of synergistic effect of fungicidal composition of the present invention

[0484] A synergistic effect of two or more products exists whenever the action of an active ingredient combination is greater than the sum of the actions of the individual components. Synergism was calculated by using Colby’s method (Weeds, vol. 15 No. 1 (Jan 1967), pp. 20-2.

[0485] The synergistic action expected for a given combination of two active components can be calculated as follows:

[0486] XY

[0487] E = (X + Y) - 100

[0488] The synergistic action expected for a given combination of three active components can be calculated as follows:

[0489] (XY+YZ+XZ) (XYZ)

[0490] E = (X + Y + Z) - + - 100 10000

[0491] Where:

[0492] E represents expected percentage of fungicidal control for the combination of the two or three actives ingredients at defined doses (for example equal to x, y and z, respectively).

[0493] X is the percentage of fungicidal control observed by the compound (Myclobutanil) at a defined dose (equal to x).

[0494] Y is the percentage of fungicidal control observed by the compound (Tebuconazole) at a defined dose (equal to y).Z is the percentage of fungicidal control observed by the compound (Mancozeb) at a defined dose (equal to z).

[0495] When the percentage of fungicidal control observed for the combination is greater than the expected percentage, there is a synergism effect.

[0496] Observed control (%)

[0497] Ratio = - Expected control (%)

[0498] Ratio of O / E > 1, synergism observed

[0499] The present invention is illustrated by way of examples, the examples are meant for illustrative purposes and should not be construed as limiting.

[0500] Experiment for Synergistic activity of fungicidal composition of present invention:

[0501] Example 1- Details of experiment on grape crop:

[0502] Field experiment for synergistic activity of Myclobutanil + Tebuconazole + Mancozeb for the control of powdery mildew and anthracnose in grape crop was conducted at farmer field.

[0503] To evaluate the synergistic effect, grape (Variety: Thompson seedless) crop was sown in 25 m x 25 m plots maintaining 2.5 m x 0.50 m plant distance with three replications and in Randomized Block Design (RBD). The treatments were applied as foliar spray in the form of WP formulation @ 2500 g / ha. Each active component was applied twice in different ternary and binary combinations. Solo components were also taken for comparison. The treatment details are as under:

[0504] S. No Treatments Concentration (WP)

[0505] T1 Myclobutanil + Tebuconazole + Mancozeb 0.01% + 4% + 55%

[0506] T2 Myclobutanil + Tebuconazole + Mancozeb 1.25% + 1% + 25%

[0507] T3 Myclobutanil + Tebuconazole + Mancozeb 0.64% + 8% + 48%

[0508] T4 Myclobutanil + Tebuconazole + Mancozeb 0.1% + 16% + 1%

[0509] T5 Myclobutanil + tebuconazole 0.01% + 4%

[0510] T6 Myclobutanil + tebuconazole 1.25% + 1%

[0511] T7 Myclobutanil + tebuconazole 0.64% + 8%

[0512] T8 Myclobutanil + tebuconazole 0.1% + 16%

[0513] T9 Myclobutanil + Mancozeb 0.01% + 55%

[0514]

[0515] T10 Myclobutanil + Mancozeb 1.25% + 25%Til Myclobutanil + Mancozeb 0.64% + 48%

[0516] T12 Myclobutanil + Mancozeb 0.1% + 1%

[0517] T13 Tebuconazole + Mancozeb 4% + 55%

[0518] T14 Tebuconazole + Mancozeb 1% + 25%

[0519] T15 Tebuconazole + Mancozeb 8% + 48%

[0520] T16 Tebuconazole + Mancozeb 16% + 1%

[0521] T17 Myclobutanil 0.01%

[0522] T18 Myclobutanil 1.25%

[0523] T19 Myclobutanil 0.64%

[0524] T20 Myclobutanil 0.1%

[0525] T21 Tebuconazole 4%

[0526] T22 Tebuconazole 1%

[0527] T23 Tebuconazole 8%

[0528] T24 Tebuconazole 16%

[0529] T25 Mancozeb 55%

[0530] T26 Mancozeb 25%

[0531] T27 Mancozeb 48%

[0532] T28 Mancozeb 1%

[0533]

[0534] T29 Untreated check -

[0535] The treatments T1 to T28 were used as foliar application whereas no treatment was done for T29 control treatment. Two applications at 15 days interval were done of all treatments on the appearance of disease at experimental plots. Observations for disease Powdery mildew (Erysiphe necator) and anthracnose (Elsinoe ampilena) was recorded at before spray and 14 days after 1stand 2ndapplication by observing 3 leaves on 10 random plants per plot and per cent disease severity was calculated. It was rated as a 0—5 scale, where 0 = no infection, 1 - 1-10% leaf area infected, 2 - 11-25%, 3 - 26-50%, 4 - 51-75%, and 5 -76—100%. Percentage Disease Index was worked out using the formula, PDI = [Sum of all numerical rating / total number of observations taken x maximum disease score] x 100. Based on the per cent reduction at 14 days after second spray in disease incidence, expected control was calculated and compared with observed control. The results of the trial have been presented here under in Table 1.

[0536] Table 1: Synergistic effect of stable synergistic fungicidal composition of the present invention (Myclobutanil+ Tebuconazole + Mancozeb) against diseases (Powdery mildew and anthracnose) in grape crop

[0537] Concentration

[0538] S. No Treatments (WP) Per cent Disease Control

[0539]

[0540] Colby Observed Expected ratio 0.01% + 4% +

[0541] T1

[0542] Myclobutanil + Tebuconazole + Mancozeb 55% 77.32 53.22 1.453 T2 1.25% + 1% +

[0543] Myclobutanil + Tebuconazole + Mancozeb 25% 71.23 50.44 1.412 0.64% + 8% +

[0544] T3 Myclobutanil + Tebuconazole + Mancozeb 48% 94.32 63.96 1.475 T4 0.1% + 16% +

[0545] Myclobutanil + Tebuconazole + Mancozeb 1% 74.56 54.19 1.376 T5 Myclobutanil + tebuconazole 0.01% + 4% 24.58 29.49 0.834 T6 Myclobutanil + tebuconazole 1.25% + 1% 33.25 38.17 0.871 T7 Myclobutanil + tebuconazole 0.64% + 8% 45.56 48.97 0.930 T8 Myclobutanil + tebuconazole 0.1% + 16% 43.13 47.85 0.901 T9 Myclobutanil + Mancozeb 0.01% + 55% 33.56 40.36 0.832 T10 Myclobutanil + Mancozeb 1.25% + 25% 36.54 42 0.870 Til Myclobutanil + Mancozeb 0.64% + 48% 42.35 46.58 0.909 T12 Myclobutanil + Mancozeb 0.1% + 1% 21.43 27.57 0.777 T13 Tebuconazole + Mancozeb 4% + 55% 43.45 47.96 0.906 T14 Tebuconazole + Mancozeb 1% + 25% 26.54 31.5 0.843 T15 Tebuconazole + Mancozeb 8% + 48% 50.13 52.36 0.957 T16 Tebuconazole + Mancozeb 16% + 1% 38.76 44.45 0.872 T17 Myclobutanil 0.01% 10.11 - - T18 Myclobutanil 1.25% 27.65 - - T19 Myclobutanil 0.64% 24.35 - - T20 Myclobutanil 0.1% 17.54 - - T21 Tebuconazole 4% 21.56 - - T22 Tebuconazole 1% 14.54 - - T23 Tebuconazole 8% 32.54 - - T24 Tebuconazole 16% 36.76 - - T25 Mancozeb 55% 33.65 - - T26 Mancozeb 25% 19.84 - - T27 Mancozeb 48% 29.38 - - T28 Mancozeb 1% 12.16 - -

[0546]

[0547] T29 Untreated check - - - -

[0548] It is clearly evident from the data shown in above Table 1 for per cent disease control in grape crop that the ternary fungicidal composition of the present invention comprising Myclobutanil + Tebuconazole + Mancozeb i.e., T1 to T4 are synergistic for powdery mildew and anthracnose disease with > 1 Colby’s Ratio. The binary combination of two fungicides (Myclobutanil + Tebuconazole, Myclobutanil + Mancozeb and Tebuconazole + Mancozeb) T5 to T16 are less efficacious and no synergistic effect is shown for the control of diseases, as compared to ternary fungicidal composition of Myclobutanil + Tebuconazole +Mancozeb T1 to T4. The synergy data presented herein represent the cumulative efficacy against both powdery mildew and anthracnose.

[0549] Experiment for Bio-efficacy evaluation of fungicidal composition of present invention:

[0550] For the ternary and binary combination based on Myclobutanil + Tebuconazole + Mancozeb evaluation under field conditions, the basic test composition as Myclobutanil 0.64% + Tebuconazole 8% + Mancozeb 48% WP were manufactured specifically by the inventor. For ternary fungicidal composition, Myclobutanil 0.64% + Tebuconazole 8% + Mancozeb 48% WP was used and for binary combinations, Myclobutanil 0.64% + Tebuconazole 8% WP, Myclobutanil 0.64% + Mancozeb 48% WP and Tebuconazole 8% + Mancozeb 48% WP were used. The solo formulations of Myclobutanil 0.64% WP, Tebuconazole 8% WP and Mancozeb 48% WP were used for comparison. The other formulations namely Myclobutanil 10% WP, Tebuconazole 38.39% w / w SC and Mancozeb 75% WP available in the market were also used for comparison.

[0551] Example 2: Evaluation of the stable synergistic fungicidal composition of the present invention on grape

[0552] The synergistic composition of the present invention Myclobutanil 0.64% + Tebuconazole 8% + Mancozeb 48% WP was evaluated on grape crop variety Thompson seedless at a farmer field. The crop sowing was done in 25 x 25 m plot with Randomized Block Design (RBD) and three replications maintaining a distance of 2.5 m x 0.50 m. The observations were recorded for the following objectives.

[0553] Objectives:

[0554] 1. Bio-efficacy evaluation against powdery mildew disease on grape crop

[0555] 2. Bio-efficacy evaluation against anthracnose disease on grape crop

[0556] 3. Bio-efficacy evaluation based on per cent reduction in powdery mildew disease control

[0557] 4. Bio-efficacy evaluation based on per cent reduction in anthracnose disease control

[0558] 5. Bio-efficacy evaluation based on crop yield.

[0559] 6. Phytotoxicity evaluation on grape crop

[0560] Treatment details:

[0561] S. N Treatment (WP) a.i. dose Formulati 0. (g / ha) on dose (g or ml / ha)

[0562] T1 12 + 150

[0563] 1875

[0564]

[0565] Myclobutanil 0.64% + Tebuconazole 8% + Mancozeb 48% WP + 900T2 16 + 200

[0566] 2500 Myclobutanil 0.64% + Tebuconazole 8% + Mancozeb 48% WP + 1200

[0567] T3 20 + 250

[0568] 3125 Myclobutanil 0.64% + Tebuconazole 8% + Mancozeb 48% WP + 1500

[0569] T4 Myclobutanil 0.64% + Tebuconazole 8% WP 12 + 150 1875 T5 Myclobutanil 0.64% + Tebuconazole 8% WP 16 + 200 2500 T6 Myclobutanil 0.64% + Tebuconazole 8% WP 20 + 250 3125 T7 Myclobutanil 0.64% + Mancozeb 48% WP 12 + 900 1875 T8 Myclobutanil 0.64% + Mancozeb 48% WP 16 + 1200 2500 T9 Myclobutanil 0.64% + Mancozeb 48% WP 20 + 1500 3125 T10 Tebuconazole 8% + Mancozeb 48% WP 150 + 900 1875 Til 200 +

[0570] 2500 Tebuconazole 8% + Mancozeb 48% WP 1200

[0571] T12 250 +

[0572] 3125 Tebuconazole 8% + Mancozeb 48% WP 1500

[0573] T13 Myclobutanil 0.64% WP 16 2500 T14 Tebuconazole 8% WP 200 2500 T15 Mancozeb 48% WP 1200 2500 T16 Myclobutanil 10% WP 0.004% 0.04% T17 Tebuconazole 38.39% w / w SC 236.5 550 T18 Mancozeb 75% WP 1.5kg 2kg T19 Untreated - - T20 Myclobutanil 0.64% + Tebuconazole 8% + Mancozeb 48% WP (for 32 + 400

[0574]

[0575] phytotoxicity analysis only) + 2400 5000

[0576] Methodology:

[0577] The treatments T1 to T18 and T20 were used as foliar application whereas no treatment was done for T19 i.e., control treatment. All treatments were applied at the time of initiation of fungal disease in the experimental plots.

[0578] Observations for disease Powdery mildew (Erysiphe necator) and anthracnose (Elsinoe ampilend) was recorded at before spray and 14 days after 1stand 2ndapplication by observing 3 leaves on 10 random plants per plot and per cent disease severity was calculated. It was rated as a 0-5 scale, where 0 = no infection, 1 = 1-10% leaf area infected, 2 = 11-25%, 3 = 26-50%, 4 = 51-75%, and 5 = 76-100%. Percentage Disease Index was worked out using the formula, PDI = [Sum of all numerical rating / total number of observations taken x maximum disease score] x 100. The per cent reduction in disease incidence was calculated over control. The fruit yield was recorded at crop harvest. The observations for phyto toxicity on grapes crop at 1, 3, 7, 10 and 14 days after 1stspray were also recorded. The data were subjected to statistical analysis of variance. Results are presented in Table 2A, 2B, 2C and 2D.Results:

[0579] Table 2A: Field bio-efficacy evaluation of stable synergistic fungicidal composition comprising Myclobutanil 0.64% + Tebuconazole 8% + Mancozeb 48% WP against powdery mildew of grapes S. No Treatments (WP) a.i. dose For Per cent disease index Per cent (g / ha) mula on leaves reduction tion over control dose

[0580] (g or Befor 14 14 14 14 ml / h e days days days days s after after after after a) pray

[0581] I II II II

[0582] spray spray spra spra y y T1 Myclobutanil 0.64% + 12 + 150 1875 6.92 6.82 3.38 66.8 89.85 Tebuconazole 8% + Mancozeb + 900 (15.2 (15.14 (10.59 1

[0583] 48% WP 5) ) )

[0584] T2 Myclobutanil 0.64% + 16 + 200 2500 6.52 6.5 2.41 68.3 92.76 Tebuconazole 8% + Mancozeb + 1200 (14.7 (14.77 (8.93) 7

[0585] 48% WP 9) )

[0586] T3 Myclobutanil 0.64% + 20 + 250 3125 6.73 6.26 1.97 69.5 94.08 Tebuconazole 8% + Mancozeb + 1500 (15.0 (14.49 (8.07) 4

[0587] 48% WP 4) )

[0588] T4 12 + 150 1875 5.92 14.75 18.33 28.2 44.95 Myclobutanil 0.64% + (14.0 (22.59 (25.35 2 Tebuconazole 8% WP 8) ) )

[0589] T5 16 + 200 2500 7.13 14.18 17.05 31 48.8 Myclobutanil 0.64% + (15.4 (22.12 (24.39 Tebuconazole 8% WP 9) ) )

[0590] T6 20 + 250 3125 6.51 13.56 16.4 34.0 50.75 Myclobutanil 0.64% + (14.7 (21.61 (23.89 1 Tebuconazole 8% WP 8) ) )

[0591] T7 12 + 900 1875 6.25 16.12 23.58 21.5 29.19 Myclobutanil 0.64% + (14.4 (23.67 (29.05 6 Mancozeb 48% WP 8) ) )

[0592] T8 16 + 2500 6.56 15.81 22.67 23.0 31.92 Myclobutanil 0.64% + 1200 (14.8 (23.43 (28.43 7 Mancozeb 48% WP 4) ) )

[0593] T9 20 + 3125 5.89 15.71 22.43 23.5 32.64 Myclobutanil 0.64% + 1500 (14.0 (23.35 (28.27 5 Mancozeb 48% WP 5) ) )

[0594] T10 150 + 1875 6.69 15.77 22.4 23.2 32.73 Tebuconazole 8% + Mancozeb 900 (14.9 (23.4) (28.25 6

[0595] 48% WP 9) )

[0596] Til 200 + 2500 6.25 15.21 21.5 25.9 35.44 Tebuconazole 8% + Mancozeb 1200 (14.4 (22.95 (27.62 9

[0597] 48% WP 8) ) )

[0598] T12 250 + 3125 6.49 14.81 20.7 27.9 37.84 Tebuconazole 8% + Mancozeb 1500 (14.7 (22.63 (27.06 3

[0599]

[0600] 48% WP 6) ) )T13 16 2500 6.62 17.36 25.02 15.5 24.86 (14.9 (24.62 (30.01 2 Myclobutanil 0.64% WP 1) ) )

[0601] T14 200 2500 6.44 17.81 25.52 13.3 23.36 (14.7) (24.96 (30.34 3 Tebuconazole 8% WP ) )

[0602] T15 1200 2500 6.02 18.45 27.41 10.2 17.69 (14.2) (25.44 (31.57 2 Mancozeb 48% WP ) )

[0603] T16 0.004% 0.04 6.65 17.08 24.82 16.8 25.47 % (14.9 (24.41 (29.88 9 Myclobutanil 10% WP 4) ) )

[0604] T17 Tebuconazole 38.39% w / w SC 236.5 550 6.06 17.61 25.2 14.3 24.32 (14.2 (24.81 (30.13 1

[0605] 5) ) )

[0606] T18 Mancozeb 75% WP 1.5kg 2kg 6.84 18.25 26.79 11.1 19.55 (15.1 (25.29 (31.17 9

[0607] 6) ) )

[0608] T19 Untreated - 6.52 20.55 33.3 - - (14.7 (26.96 (35.24

[0609] 9) ) )

[0610] SE(m) NS 0.10 0.37 - -

[0611]

[0612] CD(p=0.05) 0.30 1.13 - - Figures in parentheses are angular transformed values; NS= Non-significant

[0613] Table 2B: Field bio-efficacy evaluation of stable synergistic fungicidal composition comprising Myclobutanil 0.64% + Tebuconazole 8% + Mancozeb 48% WP against anthracnose of grapes S. No Treatments (WP) a.i. Form Per cent disease index Per cent dose ulatio on leaves reduction over (g / ha n dose control

[0614] ) (g or

[0615] ml / ha Befor 14 14 7 14 e days days days days )

[0616] spray after after after after I II II II

[0617] spray spray spray spray T1 Myclobutanil 0.64% + 12 + 1875 8.56 7.97 3.3 54.66 89.83 Tebuconazole 8% + Mancozeb 150 + (17.01 (16.4) (10.47

[0618] 48% WP 900 ) )

[0619] T2 Myclobutanil 0.64% + 16 + 2500 8.66 7.4 2.67 57.91 91.77 Tebuconazole 8% + Mancozeb 200 + (17.11 (15.79 (9.4)

[0620] 48% WP 1200 ) )

[0621] T3 Myclobutanil 0.64% + 20 + 3125 8.58 6.98 2.47 60.3 92.39 Tebuconazole 8% + Mancozeb 250 + (17.03 (15.32 (9.04)

[0622] 48% WP 1500 ) )

[0623] T4 12 + 1875 8.07 13.34 19.15 24.12 40.99 Myclobutanil 0.64% + 150 (16.5) (21.42 (25.95

[0624] Tebuconazole 8% WP ) )

[0625] T5 Myclobutanil 0.64% + 16 + 2500 9.15 13 18.64 26.05 42.56

[0626]

[0627] Tebuconazole 8% WP 200(17.61 (21.13 (25.58

[0628] ) ) )

[0629] T6 20 + 3125 9.17 12.67 18.21 27.93 43.88 Myclobutanil 0.64% + 250 (17.63 (20.85 (25.26 Tebuconazole 8% WP ) ) )

[0630] T7 12 + 1875 9.67 12.72 17.93 27.65 44.75 Myclobutanil 0.64% + Mancozeb 900 (18.12 (20.89 (25.05

[0631] 48% WP ) ) )

[0632] T8 16 + 2500 9.7 12.32 17.46 29.92 46.19 Myclobutanil 0.64% + Mancozeb 1200 (18.15 (20.55 (24.7)

[0633] 48% WP ) )

[0634] T9 20 + 3125 8.44 11.98 17.04 31.85 47.49 Myclobutanil 0.64% + Mancozeb 1500 (16.89 (20.25 (24.38

[0635] 48% WP ) ) )

[0636] T10 150 + 1875 8.69 12.36 17.43 29.69 46.29 Tebuconazole 8% + Mancozeb 900 (17.14 (20.58 (24.68

[0637] 48% WP ) ) )

[0638] Til 200 + 2500 8.45 11.93 17 32.14 47.61 Tebuconazole 8% + Mancozeb 1200 (16.9) (20.21 (24.35

[0639] 48% WP ) )

[0640] T12 250 + 3125 8.27 11.5 16.59 34.58 48.88 Tebuconazole 8% + Mancozeb 1500 (16.71 (19.82 (24.04

[0641] 48% WP ) ) )

[0642] T13 16 2500 8.38 15.64 25.75 11.04 20.65

[0643] (16.83 (23.3) (30.49 Myclobutanil 0.64% WP ) )

[0644] T14 200 2500 8.96 14.97 23.52 14.85 27.52

[0645] (17.42 (22.76 (29.01 Tebuconazole 8% WP ) ) )

[0646] T15 1200 2500 9.01 15.17 24.15 13.71 25.58

[0647] (17.47 (22.92 (29.43 Mancozeb 48% WP ) ) )

[0648] T16 Myclobutanil 10% WP 0.004 0.04% 9.33 15.47 25.45 12 21.57

[0649] % (17.79 (23.16 (30.3)

[0650] ) )

[0651] T17 Tebuconazole 38.39% w / w SC 236.5 550 9.41 14.73 22.75 16.21 29.89

[0652] (17.86 (22.57 (28.49

[0653] ) ) )

[0654] T18 Mancozeb 75% WP 1.5kg 2kg 9.36 14.79 23.01 15.87 29.09

[0655] (17.81 (22.62 (28.66

[0656] ) ) )

[0657] T19 Untreated - 9.66 17.58 32.45 - - (18.11 (24.79 (34.73

[0658] ) ) )

[0659] SE(m) NS 0.17 0.19 - -

[0660]

[0661] CD(p=0.05) 0.51 0.57 - - Figures in parentheses are angular transformed values; NS= Non-significantTable 2C: Field bio-efficacy evaluation of stable synergistic fungicidal composition comprising Myclobutanil 0.64% + Tebuconazole 8% + Mancozeb 48% WP based on yield of grapes.

[0662] S. N Treatments (WP) a.i. dose Formul Fruit % 0 (g / ha) ation Yield Increa dose (g (t / ha) se or agains ml / ha) t contro 1 T1 Myclobutanil 0.64% + Tebuconazole 8% + 12 + 150 + 1875 20.23 33.62 Mancozeb 48% WP 900

[0663] T2 Myclobutanil 0.64% + Tebuconazole 8% + 16 + 200 + 2500 21.75 43.66 Mancozeb 48% WP 1200

[0664] T3 Myclobutanil 0.64% + Tebuconazole 8% + 20 + 250 + 3125 22.23 46.83 Mancozeb 48% WP 1500

[0665] T4 Myclobutanil 0.64% + Tebuconazole 8% WP 12 + 150 1875 17.24 13.87 T5 Myclobutanil 0.64% + Tebuconazole 8% WP 16 + 200 2500 17.63 16.45 T6 Myclobutanil 0.64% + Tebuconazole 8% WP 20 + 250 3125 17.73 17.11 T7 Myclobutanil 0.64% + Mancozeb 48% WP 12 + 900 1875 16.86 11.36 T8 Myclobutanil 0.64% + Mancozeb 48% WP 16 + 1200 2500 17.53 15.79 T9 Myclobutanil 0.64% + Mancozeb 48% WP 20 + 1500 3125 17.77 17.37 T1 150 + 900 1875 17.48 15.46 0 Tebuconazole 8% + Mancozeb 48% WP

[0666] T1 200 + 1200 2500 17.87 18.03 1 Tebuconazole 8% + Mancozeb 48% WP

[0667] T1 250 + 1500 3125 18.19 20.15 2 Tebuconazole 8% + Mancozeb 48% WP

[0668] T1 16 2500 16.47 8.78 3 Myclobutanil 0.64% WP

[0669] T1 200 2500 16.63 9.84 4 Tebuconazole 8% WP

[0670] T1 1200 2500 16.5 8.98 5 Mancozeb 48% WP

[0671] T1 Myclobutanil 10% WP 0.004% 0.04% 16.58 9.51 6

[0672] T1 Tebuconazole 38.39% w / w SC 236.5 550 16.77 10.77 7

[0673] T1 Mancozeb 75% WP 1.5kg 2kg 16.69 10.24 8

[0674] T1 Untreated - 15.14

[0675] 9

[0676] CD (p=0.05) 1.24 -

[0677]

[0678] SE(m) 0.41 - DAS - Days after crop sowing, t / ha= tonnes per hectare

[0679] Table 2D: Phytotoxicity evaluation of stable synergistic fungicidal composition comprising Myclobutanil 0.64% + Tebuconazole 8% + Mancozeb 48% WP on grapesS. N Treatments a.i. dose Formulatio Phyto-toxictiy parameters 0 (g / ha) n dose (g or observed*

[0680] ml / ha) (mean data recorded at 1, 3, 7,

[0681] 10 and 14 days after 1st spray) L w N V E H T1 Myclobutanil 0.64% + 12 + 150 + 1875 0 0 0 0 0 0 Tebuconazole 8% + Mancozeb 900

[0682] 48% WP

[0683] T2 Myclobutanil 0.64% + 16 + 200 + 2500 0 0 0 0 0 0 Tebuconazole 8% + Mancozeb 1200

[0684] 48% WP

[0685] T3 Myclobutanil 0.64% + 20 + 250 + 3125 0 0 0 0 0 0 Tebuconazole 8% + Mancozeb 1500

[0686] 48% WP

[0687] T4 Myclobutanil 0.64% + 12 + 150 1875 0 0 0 0 0 0 Tebuconazole 8% WP

[0688] T5 Myclobutanil 0.64% + 16 + 200 2500 0 0 0 0 0 0 Tebuconazole 8% WP

[0689] T6 Myclobutanil 0.64% + 20 + 250 3125 0 0 0 0 0 0 Tebuconazole 8% WP

[0690] T7 Myclobutanil 0.64% + 12 + 900 1875 0 0 0 0 0 0 Mancozeb 48% WP

[0691] T8 Myclobutanil 0.64% + 16 + 1200 2500 0 0 0 0 0 0 Mancozeb 48% WP

[0692] T9 Myclobutanil 0.64% + 20 + 1500 3125 0 0 0 0 0 0 Mancozeb 48% WP

[0693] T10 Tebuconazole 8% + Mancozeb 150 + 900 1875 0 0 0 0 0 0 48% WP

[0694] Til Tebuconazole 8% + Mancozeb 200 + 1200 2500 0 0 0 0 0 0 48% WP

[0695] T12 Tebuconazole 8% + Mancozeb 250 + 1500 3125 0 0 0 0 0 0 48% WP

[0696] T13 Myclobutanil 0.64% WP 16 2500 0 0 0 0 0 0 T14 Tebuconazole 8% WP 200 2500 0 0 0 0 0 0 T15 Mancozeb 48% WP 1200 2500 0 0 0 0 0 0 T16 Myclobutanil 10% WP 0.004% 0.04% 0 0 0 0 0 0 T17 Tebuconazole 38.39% w / w SC 236.5 550 0 0 0 0 0 0 T18 Mancozeb 75% WP 1.5kg 2kg 0 0 0 0 0 0 T19 Untreated - T20 Myclobutanil 0.64% + 32 + 400 + 5000 0 0 0 0 0 0 Tebuconazole 8% + Mancozeb 2400

[0697]

[0698] 48% WP

[0699] L - Leaf injury on tips / surface, W - Wilting, N - Necrosis, V - Vein clearing, E - Epinasty, H - Hyponasty

[0700] *Based on 0-10 scale where: 0=0%, 1=1-10%, 2=11-20%, 3=21-30%, 4=31-40%, 5=41-50%,

[0701]

[0702] 6=51-60%, 7=61-70%, 8=71-80%, 9=81-90%, 10=91-100%From the examples, it is clearly seen that the stable synergistic fungicidal composition of the present invention is superior for controlling the Powdery mildew (Erysiphe necator) and anthracnose (Elsinoe ampilena) in grapes at 14 days after 1st& 2ndspray (Table 2A and 2B) in grapes as compared to the other fungicides such as Myclobutanil 10% WP, Tebuconazole 38.39% w / w SC and Mancozeb 75% WP available in the market. The yield of grapes also improved in the ternary fungicidal composition of Myclobutanil + Tebuconazole + Mancozeb WP as compared to binary and solo compositions (Table 2C). The disclosed stable synergistic fungicidal composition comprising Myclobutanil + Tebuconazole + Mancozeb WP @ 1875, 2500, 3125 and 5000 ml / ha further showed no phytotoxicity in the grapes crop even after 1, 3, 7, 10 and 14 days after 1stspray (Table 2D).

[0703] It is evident from the above data that the stable synergistic fungicidal composition of the present invention i.e., Myclobutanil + Tebuconazole + Mancozeb WP resulted in good control of Powdery mildew (Erysiphe necator) and anthracnose (Elsinoe ampilena) in grapes with higher respective yields as compared to the reference standard products (binary compositions and solo products). Further, the composition of present invention is resulted synergistic.

[0704] In particular, it has now been found, surprisingly that, for example, the fungicidal activity of the composition of present invention, compared with the fungicidal activity of individual components, is synergistic. In fact, various advantageous properties associated with the compositions according to the invention, include but are not limited to: knock down effect all developmental stages fungal growth preventing discoloration of leaves of plants and crops, enhanced tenderness to plants and crops, preventing ageing of plants and crops and other advantages familiar to a person skilled in the art.

[0705] From the above investigations, it will be observed that numerous modifications and variations can be effectuated without departing from the true spirit and scope of the novel concepts of the present invention. It is to be understood that no limitations with respect to the specific embodiments illustrated is intended or should be inferred. It should be understood that all such modifications and improvements have been deleted herein for the sake of conciseness and readability but are properly within the scope of the following claims.

Claims

1. I / WE CLAIM1. A stable synergistic fungicidal composition comprising:A. Myclobutanil or its agrochemically acceptable salts, esters and derivatives;B. Mancozeb or its agrochemically acceptable salts, esters and derivatives; andC. Tebuconazole or its agrochemically acceptable salts, esters or its derivatives.

2. The stable synergistic fungicidal composition as claimed in claim 1, comprising:A) Myclobutanil or its agrochemically acceptable salts, esters and derivatives, in the range of 0.001-90% by weight of the composition;B) Mancozeb or its agrochemically acceptable salts, esters and derivatives, in the range of 0.001-90% by weight of the composition; andC) Tebuconazole or its agrochemically acceptable salts, esters or its derivatives in the range of 0.001-90% by weight of the composition3. A stable synergistic fungicidal composition comprising:A) Myclobutanil or its agrochemically acceptable salts, esters and derivatives, in the range of 0.001-90% by weight of the composition;B) Mancozeb or its agrochemically acceptable salts, esters and derivatives, in the range of 0.001-90% by weight of the composition;C) Tebuconazole or its agrochemically acceptable salts, esters or its derivatives in the range of 0.001-90% by weight of the composition; andD) At least one or more additive.

4. The stable synergistic fungicidal composition as claimed in claim 4, whereinA) Myclobutanil or its agrochemically acceptable salts, esters and derivatives, in the range of 0.001-90% by weight of the composition, in the range of 0.001-90% by weight of the composition;B) Mancozeb or its agrochemically acceptable salts, esters and derivatives, in the range of 0.001-90% by weight of the composition;C) Tebuconazole or its agrochemically acceptable salts, esters or its derivatives in the range of 0.001-90% by weight of the composition; andD) At least one or more additive selected from urea clathrate, Siloxane Polyalkylene oxide copolymer, tallow amine ethoxylate, ammonium sulphate, and epoxide soybean oil either alone or in combination thereof, in the range of 0.001-20% by weight of the composition.

5. The stable synergistic fungicidal composition as claimed in claims 1-4, which further comprises one or more agrochemically acceptable excipients.

6. The stable synergistic fungicidal composition as claimed in any one of claims 1 to 5, further comprises agrochemically acceptable excipients selected from the group consisting of surfactant(s), dispersing agent(s), co-dispersant, anti-freezing agent(s), emulsifier(s) (anionic and non-ionic), anti-foaming agent / defoamer(s), wetting agent(s), antimicrobial / anti -bacterial agent(s), anti-caking agent, thickening agent / thickener(s), quick coating agent(s) or sticking agents / sticker(s), spreader(s), binder(s), pH-adjusting agent(s), anti-caking agent(s), adjuvant(s), filler(s) / suspension aid(s), colorant(s), carrier(s), buffering agent(s), polymer(s)rheology modifier(s), solvent(s), co-solvent(s), biocide(s), protective colloid(s), carrier(s), adhesive(s), thixotropic agent(s), penetration agent(s), stabilizer(s), sequestering agent(s), solid or liquid carrier / additive or a combination thereof.

7. The stable synergistic fungicidal composition as claimed in any one of claims 1 to 6, wherein application of the composition provides synergistic and effective control against wide range of fungi including Scab, Powdery mildew, Leafspot, Dieback, Early blight& Late blight, Premature leaf fall, Alternaria spot / blight, sooty blotch, Brown& black rust, Blight, Leafblight, Downy mildew, Blight, Loose smut, Flag smut, Collar rot, Root rot, Stem rot, Wilt, Root rot, flag smut, Fruit rot, Tikka& rust, Blast, Sheath blight, Purple blotch, Anthracnose (pod blight), Leaf spot, Anthracnose, Yellow rust and powdery, Purple blotch, Alternaria leaf spot, Stemphylium blight, Sheath Blight, Tikka leaf spot, Cercospora leaf spot, Leaf spot(Alternaria, Cercospora & Myrothecium), Leaf rust, Dollar spot, Summer patch, Brown patch, Potato blight, Smut, Bunt, Stripe rust, Yellow leaf spot, Powdery mildew, Scelerotinia rot, Black spot, Net blotch, etc.

8. The stable synergistic fungicidal composition as claimed in any one of claims 1 to 6, wherein application of the composition can be applied to various crops and plants including but not limited to Tomato, Potato, Apple, Wheat, Maize, Paddy (Rice), Jowar, Chilies, Cauliflower, Groundnut, Grapes, Guava, Banana, Cumin, Groundnut, Chickpea, Onion, Soybean, Black gram, Cabbage, Rice, Coffee, Table grapes, Perennial and annual crops, Turf, Landscape ornamentals, Fruit trees, Vines, Sunflowers, Ornamental shrubs including roses, Cereals including barley, oat, rye; Peanuts; Vegetables including onions, peas, pepper; Sugarcane, etc.

9. The stable synergistic fungicidal composition as claimed in any one of claims 1 to 6, wherein application of the composition has enhanced permeability, improved penetration capacity, uniform spray-ability, improved rain-fastness, enriched biotic factors, better flowability, enhanced spreading or coverage effect, effective storage stability, longer residual effect, improved uptake of active ingredients, and safer to the environment.

10. The stable synergistic fungicidal composition as claimed in claims 1-7, wherein the fungicidal composition has improved stability during the desired shelf life at various temperature and pH conditions and has enhanced efficacy and penetration capacity and is economically more beneficial.

11. The stable synergistic fungicidal composition as claimed in any one of the claims 1 to 6, wherein the composition is in form of Emulsifiable concentrate (EC), Capsule suspension (CS), Dispersible concentrate (DC), Dustable powder (DP), Powder for dry seed treatment (DS), Emulsifiable granule (EG), Emulsion water-in-oil (EO), Emulsifiable powder (EP), Emulsion for seed treatment (ES), Emulsion oil-in-water (EW), Flowable concentrate for seed treatment (FS), Granules (GR Micro-emulsion concentrate (MEC), Oil-dispersion (OD), Oil miscible flowable concentrate (OF), Oil miscible liquid (OL), Oil dispersible powder (OP), Suspension concentrate (SC), Suspension concentrate for direct application (SD), Suspo- emulsion (SE), Water soluble granule (SG), Soluble concentrate (SL), Spreading oil (SO),Water soluble powder (SP), Water soluble tablet (ST), Ultra-low volume (ULV) suspension, Tablet (TB), Ultra-low volume (ULV) liquid, Water dispersible granules (WG), Wettable powder (WP), Water dispersible powder for slurry seed treatment (WS), Water dispersible tablet (WT), a mixed composition of CS and SC (ZC) or a mixed composition of CS and SE (ZE) and a mixed composition of CS and EW (ZW).

12. A process for preparing a stable synergistic fungicidal composition as claimed in claims 1-9.

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