13results about How to "Achieve targeted" patented technology

The invention relates to the technical field of intelligent evaluation of garment flatness, and particularly discloses an automatic evaluation method of a non-ironing suit seam flatness grade, and the method comprises the steps: obtaining image data and physical parameter data of a seam region in response to a detection trigger signal of the seam region of a non-ironing suit; and performing key scale screening based on texture contribution degree on the image data, calculating a relevance index between feature distribution and flatness grade probability distribution under different texture scales, and determining the texture scale of which the relevance index meets a preset contribution degree condition as a target key scale. According to the method, the entropy screening mechanism based on the texture contribution degree is introduced, so that the key scale which is most effective for flatness representation can be locked from the multi-source data in a self-adaptive manner, and the refinement and pertinence of feature extraction are realized.

The invention discloses a coal mine unmanned vehicle-oriented multi-mode perception data fusion enhancement method and system, and relates to the technical field of image enhancement, and the method comprises the steps: carrying out the image quality attenuation prediction, generating a prediction visible light image quality attenuation index sequence and a prediction infrared image quality attenuation index sequence, and carrying out the prediction of the infrared image quality attenuation index sequence; formulating an adaptive visible light image enhancement strategy and an adaptive infrared image enhancement strategy; performing image enhancement on the vehicle sensing data to generate a visible light enhanced image stream and an infrared enhanced image stream; and inputting the visible light enhanced image stream and the infrared enhanced image stream into a cross-modal feature fusion plug-in for cross-modal feature alignment, generating a multi-modal fusion enhanced perception result, and transmitting the multi-modal fusion enhanced perception result to a downstream automatic driving perception decision center in real time. The technical problems of insufficient enhancement strategy adaptability and poor cross-modal fusion effect caused by micro-environment dynamic change of existing underground coal mine multi-modal sensing data are solved.

This invention discloses a machine vision-based method for detecting contaminant residues after duodenoscope reprocessing, specifically in the field of machine vision, to address the problem of accurately locating and removing contaminant residues after existing duodenoscope reprocessing. The method involves applying controlled incident angle, wavelength, and polarization state light perturbations to the outer surface and inner lumen of the duodenoscope, acquiring image sequences under perturbation, and extracting temporal brightness response features of pixel blocks. Brightness difference residuals and consistency weights are calculated at different incident angles to identify candidate abnormal regions and generate a difference map reflecting their response characteristics to a clean baseline. The difference map is segmented, analyzed for connectivity, and clustered. Combining three-dimensional coordinate continuity and surface normal consistency, the three-dimensional spatial boundary of the suspected contamination area is delineated. Within this range, directional cleaning and retesting are performed, with repeated detection until the contamination area disappears, achieving high-precision detection and efficient cleaning.

The invention provides an audio processing method and device, equipment and a storage medium, and relates to the technical field of computers. The method comprises the following steps: acquiring an audio to be played, and converting time domain data of the audio to be played into frequency domain data; detecting a tone type contained in the audio to be played based on the frequency domain data; in response to a target timbre existing in the timbre type, obtaining a timbre operator corresponding to the target timbre; and performing signal enhancement for the target tone on the frequency domain data according to the tone operator to obtain an audio to be output. According to the method, selective enhancement can be carried out by applying the timbre operator only when the target timbre is detected, so that the timbre operator is prevented from being used for all to-be-played audios without difference, and the pertinence and accuracy of audio processing are realized.

This invention relates to the field of speech recognition technology, specifically a spoken pronunciation correction and evaluation method. The method includes: constructing an audio time-series sequence containing multiple phonemes based on the standard text spoken by the user; comparing the audio features corresponding to different phonemes in the audio time-series sequence based on the standard pronunciation of each phoneme to locate the pronunciation deviation position corresponding to each phoneme; if the current phoneme has a pronunciation deviation position, performing contextual scene analysis on the pronunciation deviation position by combining the duration, interval, and tone of the preceding and following phonemes to determine the deviation type in the current phoneme's context; identifying the user's abnormal pronunciation patterns; and configuring correction weights for each abnormal pronunciation pattern based on the difference feature values ​​between any two abnormal pronunciation patterns, and determining the correction direction corresponding to each phoneme according to the correction weights of the abnormal pronunciation patterns. This achieves targeted and efficient spoken pronunciation correction.

This invention proposes a method and system for identifying and cleaning filter plate contaminants, belonging to the field of filter plate contaminant cleaning technology. The method includes: identifying contaminants on the filter plate; determining the position, size, and shape of individual contaminants; covering each contaminant using the minimum circumcircle method; determining the coordinates and radius of the minimum circumcircle center of each contaminant; determining the cleaning sequence of all contaminants; identifying multiple key points within the minimum circumcircle of each contaminant; calculating the robot arm joint angles at each key point on each contaminant using an inverse kinematics algorithm; obtaining the optimal pose of the robot arm at each key point when cleaning all contaminants; and controlling the robot arm to perform targeted cleaning of the multiple key points corresponding to each contaminant based on the optimal pose of the robot arm at each key point when cleaning all contaminants. This invention enables targeted cleaning of contaminants, improving cleaning effectiveness, efficiency, and results.

The invention belongs to the technical field of optical fiber sensing, and particularly relates to a distributed optical fiber sound source seismic source radial position detection method and system.The method comprises the steps that seismic source sample signals with the known radial distance are collected along the way of a target line where a distributed optical fiber cable is located, phase change features of the seismic source sample signals are extracted and marked, and a training data set is constructed; and a seismic source radial position identification model is obtained through machine learning training and is stored in a feature library. During detection, the system analyzes the phase characteristics of real-time vibration signals, the radial distance of the seismic source can be predicted by inputting the model, the moving trend of the seismic source can be analyzed by combining historical data, and finally a structured alarm including the position, the distance, the trend and the risk level is generated according to a distance threshold value. According to the invention, quantitative determination of the lateral distance of threat sources such as construction machinery along the optical cable can be realized, and continuous tracking and trend analysis are carried out on the movement trend of the threat sources.

The invention relates to the technical field of biological medicine, in particular to a bicyclic peptide ligand aiming at GPC3, a pharmaceutical composition and application of the bicyclic peptide ligand. The bicyclic peptide ligand provided by the invention has high binding affinity and specificity with the GPC3 protein, and can effectively realize recognition and targeting of the GPC3 protein. Compared with an antibody inhibitor, the bicyclic peptide inhibitor has significantly lower immunogenicity and can effectively reduce side effects. The bicyclic peptide ligand provided by the invention can be used as a tool for researching the action of the GPC3 protein in the physiological process, can be used as a candidate targeting molecule of an anti-tumor drug, and is used for the scenes of early diagnosis, prevention, treatment and the like of HCC and other tumors.

The present application relates to a method for preparing extracellular vesicles with reduced non-specific binding / endocytosis, which is obtained by knockout and deglycosylation of extracellular vesicle-related adhesion molecules, and the extracellular vesicles with reduced non-specific binding / endocytosis have a prolonged residence time in blood, further, IL12 and antibodies are loaded on the extracellular vesicles with reduced non-specific binding / endocytosis, to achieve the effect of IL12 "multimer" mode enhancement, further, the antibodies achieve targeting, reduce the effective concentration of IL12, improve safety, and also achieve high-efficiency inhibition of tumor growth under certain safety.

This invention belongs to the fields of pharmaceutical formulation and biomedicine, and relates to an anti-atherosclerotic hybrid exosome, its preparation method, and its application. A hybrid composed of M2 macrophage exosomes and liposomes is used as a carrier, with the carrier loaded with a ferroptosis inhibitor and atorvastatin. The drug loading and encapsulation efficiency of the ferroptosis inhibitor are 1.55–2.57% and 11.99–49.86%, respectively; the drug loading and encapsulation efficiency of atorvastatin are 1.48–12.66% and 46.4–77.31%, respectively. The hybrid exosome provided by this invention has inflammatory targeting ability and higher stability, and can avoid the first-pass effect of the liver and the clearance of the circulatory system through intravenous injection. Simultaneously, this hybrid exosome has effects such as inhibiting ferroptosis, promoting cholesterol efflux, promoting cell burial, anti-inflammation, and regulating the immune microenvironment, enabling multi-faceted treatment of atherosclerosis, thus achieving better therapeutic effects.

This invention relates to the field of wind-resistant technology for high-voltage transmission lines, and discloses a wind-resistant and vibration-damping structure for high-voltage transmission lines. The structure includes two parallel mounting bases with a central support column between them. Multiple suspension arms extending away from the center of the mounting bases are located at their corners. Each suspension arm has a cable clamp at its end for holding the transmission conductor. The structure also includes a first vibration-damping module and a second vibration-damping module. The first vibration-damping module includes a flexible connector and a counterweight. One end of the flexible connector is connected to the mounting base, and the other end is connected to the counterweight, which is located below the center of the mounting base. This invention achieves comprehensive and efficient suppression of wind-induced vibrations in high-voltage transmission lines through an innovative multi-level synergistic vibration-damping design.

The invention relates to the technical field of industrial automation testing, in particular to an industrial control equipment interface testing system, method and platform, and the system comprises a unified configuration management module, a central test scheduling engine, a multi-source test adapter layer and a comprehensive analysis report module. The method comprises the following steps: acquiring configuration information of to-be-tested industrial control equipment, and identifying an interface type and a test parameter; based on the interface type and the test parameter, calling a corresponding interface test strategy for testing to obtain a test result; and generating a comprehensive test report according to the test result. The method has the effect of improving the comprehensiveness and accuracy of the interface test of the industrial control equipment.

The application discloses a kind of azahemicyanine dyes and application thereof, compared with the dye similar to the function of novel azahemicyanine dye molecule provided by the application, the application can effectively prevent the non-specific combination of serum albumin and hemicyanine dye, and the stability, fluorescence quantum yield and stoke shift of the hemicyanine dye are enhanced;The dye synthesis step provided by the application is simple, easy to purify, and has high yield;By introducing six-membered heterocyclic ring into the side chain of azahemicyanine dye, the combination with protein is effectively avoided, the false positive interference of serum albumin on dye fluorescence signal is excluded, and kidney targeting is realized, and the high fidelity of imaging is improved;The probe NA-H2S2 synthesized based on the dye NA-6 provided by the application is used for rapid detection of the change of H2S2 concentration;The synthesis step of the dye molecule is simple, easy to purify, has excellent imaging performance, fluorescence signal is not interfered by serum albumin, and is suitable for high-fidelity imaging of kidney.