2results about How to "Efficient separation and purification" patented technology

This utility model discloses a pretreatment device for raw materials in the production of high-purity Kathon, relating to the field of Kathon production technology. The inlet of an ultrasonic reactor is connected via pipelines to a methylchloroisothiazolinone raw material tank and a deionized water tank. The outlet of the ultrasonic reactor is connected via a screw pump to a ceramic membrane device. The liquid phase outlet of the ceramic membrane device is connected via pipelines to a distillation column. The top gas phase outlet of the distillation column is connected via pipelines to a light component tank, an organic solvent tank, and a purified methylchloroisothiazolinone tank. This device achieves effective separation and purification of different components, improving product purity, while simultaneously recovering organic solvents and reducing production costs.

The invention provides a method for separating and purifying ascomycin. The method for separating and purifying ascomycin comprises the following steps: 1) adding inorganic salt into fermentation liquor containing ascomycin, adjusting the pH value of a system to be 1-4, and carrying out first ceramic membrane filtration to obtain first ceramic membrane concentrated liquor; adding alkaline buffer salt into the first ceramic membrane concentrated solution, adjusting the pH value of the system to 8-11, and carrying out second ceramic membrane filtration to obtain a second ceramic membrane concentrated solution; (2) carrying out filter pressing and water washing on the second ceramic membrane concentrated solution to obtain a filter cake, and extracting the filter cake by using an organic solvent to obtain an extracting solution; (3) cooling, crystallizing, filtering and drying the extract liquor to obtain first purified crystallis.By means of the method, cross-linked impurities such as amino acid, protein and pigment in the fermentation liquor can be effectively removed, and the effect of efficiently separating and purifying high-purity ascomycin is achieved.