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214results about How to "Fast dispersion" patented technology

Amorphous Venetoclax and pharmaceutic adjuvant solid dispersoid and preparation method thereof

The invention relates to an amorphous Venetoclax and pharmaceutic adjuvant solid dispersoid and a preparation method thereof. The amorphous Venetoclax and pharmaceutic adjuvant solid dispersoid is prepared from Venetoclax and pharmaceutic adjuvants according to the weight ratio of 1:(0.1 to 100), wherein the Venetoclax is in an amorphous state; and in the X-ray powder diffraction spectrum of the solid dispersoid, no Venetoclax crystal feature peaks exist after the background peaks of the pharmaceutic adjuvants are eliminated. The Venetoclax and pharmaceutic adjuvant solid dispersoid provided by the invention has the advantages that the stability and the dispersibility are good; the dissolution rate of the Venetoclax is increased; the improvement of the bioavailability on the medicine preparation and the adsorption of the body on the medicine can be facilitated; and under the acceleration test conditions, high physical stability and chemical stability can be maintained. The preparationmethod of the amorphous Venetoclax and pharmaceutic adjuvant solid dispersoid has the advantages that the operation is simple; the cost is low; the reproducibility is high; the realization is easy; and the method is suitable for industrial production.
Owner:CHANGZHOU AINUOXINRUI PHARMA LTD

Composition for solid plasticized high-flame-retardant PVC sheath material and preparation method of composition

The invention relates to a composition for a solid plasticized high-flame-retardant PVC (polyvinyl chloride) sheath material and a preparation method of the composition, and belongs to the technical field of cable materials. According to the composition and the preparation method, an Am-168 solid plasticizer and sodium antimonide flame retardant are introduced into the high-flame-retardant PVC cable sheath material; the traditional fire retardant damages other properties of the material while achieving the flame-retardant purpose; however, sodium antimonide does not affect body properties of the material while achieving the flame-retardant modification purpose due to a structure and constituent characteristics of sodium antimonide; the compatibility and adhesive strength with plastic are improved greatly; the dispersity is good; a loading level can be raised; the impregnating property is good; the mixing time is short; uniform flowing is realized in a mold; and forming is good. Mechanical properties of the material are improved, and the composite high-flame-retardant cable sheath material prepared by the composition for the composite high-flame-retardant cable sheath material has good mechanical properties and flame resistance.
Owner:JIANGSU BAOYUAN GAOXIN ELECTRIC

Lithium iron phosphate cathode slurry of lithium ion battery, preparation method of lithium iron phosphate cathode slurry and cathode pole piece

The invention discloses lithium iron phosphate cathode slurry of a lithium ion battery, a preparation method of the lithium iron phosphate cathode slurry and a cathode pole piece, and belongs to the field of lithium ion batteries. The positive electrode slurry comprises 93-97 parts of a lithium iron phosphate positive electrode active substance, 2-5 parts of a binder and 1-3 parts of a conductiveagent, wherein the specific surface area of the lithium iron phosphate positive electrode active substance is 6-12 m<2>/g, and the binder contains an acrylate multipolymer with a substitution degree of 0.73-3.0. The preparation method comprises the following steps: fully mixing a conductive agent and a binder with the same mass to form a conductive glue solution with the pH value of 8-11, then adding the lithium iron phosphate positive electrode active substance and the binder, performing full stirring and dispersing in the conductive glue solution, and finally defoaming and adjusting the viscosity to obtain the lithium iron phosphate positive electrode slurry of the lithium ion battery. Components in the positive electrode slurry are uniformly dispersed, sedimentation is avoided, and theuse standard of an electrode is met.
Owner:蜂巢能源科技(马鞍山)有限公司

Production method of antibacterial coating, antibacterial coating and ventilated antibacterial film containing antibacterial coating

The invention provides a production method of an antibacterial coating, the antibacterial coating and a ventilated antibacterial film containing the antibacterial coating. The production method comprises the following steps: S1: weighing materials in a raw material formula in parts by weight; S2: adding cyclomethyl methacrylate, butyl acrylate, nano TiO, methacrylic acid hydroxylpropyl sulfonic acid, acrylic resin, polyoxyethylene ether, an emulsifying agent, de-ionized water, a pH regulator and a film-forming addition agent into a mixer and pre-stirring, wherein the stirring speed is 3000rpm/min to 6000rpm/min and the stirring time is 0.1h to 0.2h; S3: fusing and extruding the mixed raw materials obtained by the step S2 through an extruder, tabletting and crushing through a tabletting machine, micro-crushing by a crusher and screening in a rotary manner in sequence to finally obtain antibacterial coating powder. The production method of the antibacterial coating, provided by the invention, is finished through three steps; the production process method is simple and the production method is simple; the production time is short and the production efficiency is greatly improved.
Owner:江苏科德宝建筑节能科技有限公司

Composition of amorphous vortioxetine or amorphous vortioxetine salt and pharmaceutical adjuvants, and preparation method thereof

The invention relates to a composition of vortioxetine or pharmaceutically acceptable vortioxetine salt and pharmaceutical adjuvants, and a preparation method thereof. The composition includes vortioxetine or pharmaceutically acceptable vortioxetine salt and two or more pharmaceutical adjuvants, and a weight ratio of the vortioxetine or pharmaceutically acceptable vortioxetine salt to all the pharmaceutical adjuvants is 1:(0.1-100), wherein the vortioxetine or pharmaceutically acceptable vortioxetine salt in the composition has an amorphous form, and no characteristic peak of the vortioxetine or pharmaceutically acceptable vortioxetine salt exists in an X-ray powder diffraction spectrum of the composition, subtracting the background peaks of the pharmaceutical adjuvants. The composition of vortioxetine or pharmaceutically acceptable vortioxetine salt and pharmaceutical adjuvants has good stability and dispersibility, increases the dissolvability of the vortioxetine or pharmaceutically acceptable vortioxetine salt, is in favor of improving the bioavailability of a medicinal preparation and the medicine absorption of bodies, and keeps good physical stability and chemical stability under accelerated test conditions. The preparation method of the amorphous composition has the advantages of simplicity in operation, low cost, good reappearance, easiness in realization, and suitableness for industrial production.
Owner:CHANGZHOU FANGNAN MEDICINE TECH CO LTD

Collision atomization stream-extrusion combustion system of internal-combustion engine

The invention discloses a collision atomization stream-extrusion combustion system of an internal-combustion engine, which belongs to the field of formation and combustion of gas mixtures of engines. The system comprises a combustion chamber (4) which consists of a cylinder cover (1), a cylinder sleeve (2) and a piston (3) and an oil injection nozzle (5) serving as a multi-hole oil nozzle, wherein a bump (8) is arranged in the center of the piston (3) and is formed by a folding fan surface which uses a convex top (9) as a center and is continuously and radially distributed. A one-time oil bundle is diffused through a collision part along a collision surface and cannot be accumulated on a drop point, and mist spray has a high diffusion speed and a large distributed spatial range and is not close to the wall of the combustion chamber, so that the involved quantity of air is increased; secondary atomization is realized, so that the grain size of the mist spray is thinned, and the mist spray is more uniformly distributed under the action of extrusion flow; therefore, a relatively uniform gas mixture can be relatively quickly formed; and the quality of a combustible gas mixture of the engine is effectively improved, so that combustion is quick and complete.
Owner:JIANGSU UNIV

Solid dispersoid of selexipag and pharmaceutic adjuvant and preparation method of solid dispersoid

The invention discloses amorphous selexipag, which is characterized in that the characteristic peak of the selexipag does not exist in an X-ray powder diffraction spectrum. The invention discloses a preparation method of the amorphous selexipag, a solid dispersoid of the amorphous selexipag and a pharmaceutic adjuvant and a preparation method of the solid dispersoid. The solid dispersoid is prepared from the selexipag and the pharmaceutic adjuvant; the weight ratio of the selexipag to the pharmaceutic adjuvant is 1 to (0.1 to 100), wherein the selexipag is in an amorphous state; the X-ray powder diffraction spectrum of the solid dispersoid has no characteristic peak of a crystal of the selexipag after the background peak of the pharmaceutic adjuvant is deducted. The solid dispersoid of the selexipag and the pharmaceutic adjuvant, which is provided by the invention, is favorable in stability and dispersity, is used for increasing the dissolution rate of the selexipag, is used for more beneficially improving the bioavailability of a medicinal preparation and the absorption of an organism to a medicine, and in an accelerated test condition, can be used for maintaining favorable physical stability and chemical stability. The preparation method of the amorphous solid dispersoid, which is provided by the invention, is simple to operate, low in cost, good in repeatability and easy to realize, and is suitable for industrialized production.
Owner:CHANGZHOU FANGNAN MEDICINE TECH CO LTD

Flame-retarding dyeing glue solution and flame-retarding paint-free solid wood board applying same

The invention discloses a flame-retarding dyeing glue solution. The flame-retarding dyeing glue solution is prepared from the following components in parts by weight: 70 to 80 parts of a thermosettingresin glue solution, 6 to 10 parts of a penetrating agent, 10 to 20 parts of color concentrate, 2 to 6 parts of a fireproof flame retardant, 0.5 to 2 parts of a nano negative ion powder solution and1.5 to 3 parts of a dispersant; the weight part sum of the components of the flame-retarding dyeing glue solution is 100 percent. The invention further discloses a preparation method of the flame-retarding dyeing glue solution; the preparation method comprises the following steps: uniformly mixing all the components; stirring to prepare the flame-retarding dyeing glue solution. The flame-retardingdyeing glue solution prepared by the invention is mainly applied to dyeing of various solid wood boards and is especially applicable to carbonized solid wood boards; finally, a prepared flame-retarding paint-free solid wood board has a plurality of properties including high density, diversified colors and lusters, flame-retarding performance, water-proof performance, paint-free performance, insect prevention, corrosion prevention, no cracking, no deformation and the like; the surface of the board can be directly engraved and a decoration layer does not need to be arranged, so that proceduresare saved and the cost is saved; meanwhile, negative ions can be released to purify air and the flame-retarding dyeing glue solution is environmentally friendly and durable.
Owner:GUANGDONG HUANGTIAN ENVIRONMENTAL PROTECTION TECH CO LTD
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