164results about How to "Prolong degradation time" patented technology

The invention discloses a biodegradable medical hydrogel and a preparation method and application of the hydrogel, and particularly discloses a biodegradable medical hydrogel which is formed by in-situ crosslinking and shaping. The gelation time of the hydrogel is less than 20s, the swelling rate is 0-600%, the fracture strength is not less than 50mmHg, the time of beginning degradation is 3-40d and the degradation time is 7-180d. The raw materials for preparing the hydrogel comprise a first compound component containing a nucleophilic functional group and a second compound component containing an electrophilic functional group, and the two components are physically mixed by a mixing tool and subjected to covalent crosslinking to form the hydrogel. The physical property and biodegradability of the hydrogel can be adjusted by changing the ratio of compound components of the first component or the second component; and the hydrogel is controllable in performance and simple to operate, and can be used for organism environments of different parts.

The invention belongs to the field of biomedical materials and relates to a polymer composite fiber surgical suture line capable of sustaining and controlling the release of therapeutic medicaments and a preparation method thereof. Nucleated hollow silicon dioxide submicron spheres containing the therapeutic medicaments are dispersed in aqueous solution of a polymer; the nucleated hollow silicon dioxide submicron spheres containing the therapeutic medicaments are embedded in polymer fibers by using a spinning method to form the polymer composite fiber surgical suture line of the nucleated hollow silicon dioxide submicron spheres embedded and loaded the therapeutic medicaments to obtain the polymer composite fiber surgical suture line capable of sustaining and controlling the release of the therapeutic medicaments. The embedded nucleated hollow silicon dioxide submicron spheres are dispersed in the polymer fibers and filled with the medicaments and has a sustained release function. Themedicaments are released by slow diffusion and the gradual degradation of the polymer fibers. The loaded medicaments have functions of resisting bacteria and inflammation, killing tumor cells remaining after surgery and the like.

The invention discloses a preparation method of acellular matrix gels, which is implemented through that natural tissues or organs are treated by using a decellation technology, the obtained object is subjected to subsequent chalking and enzymatic digestion treatment so as to obtain an acellular matrix solution, and the acellular matrix solution can be prepared into acellular matrix gels with various shapes and properties under mild conditions. Acellular matrix gels prepared by using the preparation method disclosed by the invention can be used in injectable gels and can be processed and formed into gels, the formed gel has a nano fiber microstructure, and the microstructure has a positive effect on regulating the behaviors of cells.

The invention belongs to the technical fields of biodegradable material modification and application, and relates to a controllable fully biodegradable mulching film and a preparation method thereof.The controllable fully biodegradable mulching film comprises the following raw materials in parts by weight: 1-50 parts of high-crystallinity polylactic acid, 10-90 parts of polybutylene adipate / butylene terephthalate, 0-50 parts of poly propylene carbonate, 0.1-2 parts of a plasticizer, 0.1-2 parts of a chain extender, 0.1-1 part of a lubricant, 0.1-1 part of a dispersant, 0.1-1 part of an opening agent, 1-3 parts of a compatibilizer, 0.1-8 parts of a gas barrier, 0-1 part of an antioxidant, 0-1 part of a light stabilizer, 0.1-2 parts of an anti-hydrolysis agent and 0-3 parts of an antibacterial agent. The raw materials are pretreated and uniformly mixed, the controllable fully biodegradable mulching film is obtained by extrusion and blow molding, and the thickness of the mulching film is0.005 to 0.020 mm. The fully biodegradable mulching film provided by the invention has good mechanical properties, excellent heat preservation and moisture retention performance, and can be completely degraded by itself; the mulching film degradation rate can be regulated according to the 'mulching film function period' of different crop mulching films in different regions to meet the needs of different crops in different regions.

The invention provides crosslinking sodium hyaluronate gel and a preparation method thereof. The preparation method comprises the following steps: dropwise adding a crosslinking agent in an aqueous alkaline solution of sodium hyaluronate and carrying out crosslinking reaction; after reaction is finished, adjusting pH value of a system to be 7.1-7.5 with acid; stirring for 1-2 hours; and then precipitating with anhydrous ethanol to obtain the crosslinking sodium hyaluronate gel. The shortcoming that the proportion of crosslinking modification degree in a traditional crosslinking technology is lower (about 10%) is overcome effectively, and the proportion of the crosslinking modification degree is increased to be about 60% and is controllable. An ultrasonic crosslinking technology is introduced, the proportion of the crosslinking modification degree in crosslinking hyaluronic acid can be increased effectively, the proportion of suspension modification degree is reduced, and degradation time of a material is prolonged.

The invention relates to a decellularization cornea preparation method, which adopts steps of corneal epithelium layer removing, ultraviolet cross-linking, viral inactivation, decellularization treatment, gradient dehydration, radiation protection and sterilization. According to the present invention, the prepared decellularization cornea has characteristics of complete antigen removing, no excitation of host acquired immunity reaction, good biocompatibility, low damage on nature corneal stroma, maintaining of structure characteristics of the nature corneal, and maintaining of effective components of the nature corneal so as to provide physical and chemical properties similar to the nature corneal; and after the prepared decellularization cornea is transplanted, animal experiment results show that characteristics of transparent transplanted cornea, no scar formation, no melting generation and no neovascularization are provided, the transplanted cornea and the recipient bed are completely integrated after transplanting a month, the transplanted cornea is subjected to complete epithelization after three months, corneal stroma cells migrate toward the decellularization cornea graft so as to prove that the tissue just takes place slow reconstruction, and the transplanted cornea after 6 months does not show significant difference in histology and appearance detection compared with the nature cornea.

The invention relates to a gel hemostatic material and a preparation method thereof. The gel hemostatic material achieves the effect of blocking hemostasis in such a way that a nucleophilic polymer and an amino acid oligomer are in cross-linking reaction with an electrophile polymer to generate a three-dimensional polymer in situ. A gel hemostatic material composition and a preparation method thereof have the advantages that the raw material ratio is controlled accurately, the reasonable gel forming time can be achieved, the gel forming time is less than 10 seconds, the expected strength is relatively high, and the testing result shows that the elongation at break of the biologic gel hemostatic material is 300-600 percent, and the compression strength of the biologic gel hemostatic material is larger than 3 Mpa; the requirement of surgical operation can be met well.

The invention provides a treatment method of a magnesium alloy material capable of being absorbed by a human body and a magnesium alloy composite layer. The treatment method comprises the following steps: (1) the magnesium alloy material capable of being absorbed by the human body is washed to remove surface pollutants; (2) the magnesium alloy material capable of being absorbed by the human body is put in electrolyte solution containing silicon, micro-arc oxidation treatment is carried out under the condition that the voltage is larger than 200 to 600V, so as to lead the surface of the magnesium alloy material capable of being absorbed by living creature to form a micro-arc oxidation film layer; and (3) the magnesium alloy material capable of being absorbed by the human body after micro-arc oxidation treatment is washed and then dried. The magnesium alloy composite layer comprises the magnesium alloy material capable of being absorbed by the human body as matrix and the micro-arc oxidation film layer which covers the surface of the matrix and has the thickness of 0.5 to 50 microns; the micro-arc oxidation film layer comprises an inner layer and an outer layer, wherein the inner layer is an magnesium oxide layer and the outer layer is a crystalline compound layer of magnesium silicate or / and magnesium metasilicate. The magnesium alloy composite layer achieves the purpose of prolonging the degradation time of magnesium alloy.

A hydrogel tissue adhesive having increased degradation time is described. The hydrogel tissue adhesive is formed by reacting an oxidized polysaccharide with a water-dispersible, multi-arm amine in the presence of a polyol additive, which retards the degradation of the hydrogel. The hydrogel may be useful as a tissue adhesive or sealant for medical applications, including but not limited to, ophthalmic applications such as sealing wounds resulting from trauma such as corneal lacerations, or from surgical procedures such as vitrectomy procedures, cataract surgery, LASIK surgery, glaucoma surgery, and corneal transplants; neurosurgery applications, such as sealing the dura; as a plug to seal a fistula or the punctum; adhesion prevention to prevent undesired tissue to tissue adhesions resulting from trauma or surgery; and as a hemostat sealant.

The invention relates to a bionic nerve graft used for peripheral nervous recovery and a preparation method and application thereof. The bionic nerve graft comprises a chitosan film conduit and a fibrous protein hydrogel beam positioned in the chitosan film conduit, wherein the fibrous protein hydrogel beam is prepared from fibrous protein through an electrospinning technique. The bionic nerve graft prepared by the preparation method is formed by the filling of the chitosan film conduit and the fibrous protein hydrogel beam of a multi-stage orientation structure, wherein a nerve regrowth space is effectively supported by a chitosan film, the orientational regeneration of a nerve axon is effectively guided by the fibrous protein hydrogel beam of multi-stage orientation, the cell affinity and the mechanical property of whole materials are good, and in addition, degrading speed and the repairing speed of peripheral nervous tissues are matched.

The invention discloses a temporary plugging agent with tassel-shaped two ends as well as a preparation method and application thereof. The preparation method comprises the following steps: doubling and compounding water-swelling deformed fibers and high-strength rigid fibers to form a temporary plugging fiber bundle; knotting the temporary plugging fiber bundle to form a temporary plugging fiberbundle of which the middle is provided with a tassel knot main body and the two ends are in a tassel shape; and carrying out dipping treatment on the temporary plugging fiber bundle with the tassel-shaped two ends by using polyester resin to obtain the temporary plugging agent with the tassel-shaped two ends. The pressure bearing strength of the temporary plugging agent with the tassel-shaped twoends is as high as 70 MPa, the temporary plugging agent can plug shot holes and even deformed shot holes, can reduce the using amount of bridge plugs and the temporary plugging agent, or even replacethe bridge plugs to form more effective plugging, and the cost is reduced; the degradation performance is flexible and controllable, the time for drilling a bridge plug can be saved by selecting a degradable material, the construction cost is reduced, the construction safety is ensured, and the purpose of temporary plugging steering can be achieved by adding a small amount of tassel-shaped temporary plugging agent into a fracturing fluid.

The medical collagen material is made through the processes of chondroitin sulfate crosslinking, high temperature vacuum drying and ethylene oxide. Is has stable molecule structure and better anti-seepage and anti-stick performance, and is used in repairing cerebral dura mater, spinal dura mater and peripheral nerve.

The invention discloses a degradable seedling culture cup, which comprises the following components in parts by weight: 10-20% of waste paper pulp, 50-75% of plant fiber and 5-10% of adhesive, wherein the waste paper pulp is formed by directly pulping recycled waste paper without deinking and disinfecting processing, production cost is low, the plant fiber is formed by smashing straws, and the adhesive is vegetable gelatin. According to the degradable seedling culture cup disclosed by the invention, the recycled waste paper and straws are used as main raw materials to make waste profitable, and cost is lowered. After the waste paper pulp and the adhesive are used, the toughness of the degradable seedling culture cup is improved, and the usability is improved. In addition, the seedling culture cup degrading time is prolonged by the adhesive, more time is obtained for the market sale of a new seedling growth and culture mechanism, and therefore, the degradable seedling culture cup is worth popularizing.

The invention discloses a porous bladder acellular matrix retaining bioactive factors and a preparation method thereof. A bladder of a pig, a rabbit, a dog or cattle is handled by digestive juice, hypotonic buffer solution, hypertonic buffer solution with surfactants, buffer solution with nuclease, and deionized water. An abacterial bladder acellular matrix is obtained by cooling, freezing out and sterilizing. The bladder acellular matrix is not provided with cells, an urinary tract epithelial layer, a submucous layer or a blood circulatory system, thus having good biocompatibility and appropriate ultrastructural structure. Bioactive factors are retained, including cell adhesive factors, growth factors and chemokines. Therefore, the bladder acellular matrix is an ideal scaffold material for a bladder in tissue engineering.

The invention relates to the field of biological medicinal materials, and discloses a reinforced anti-adhesion composite gel. The reinforced anti-adhesion composite gel comprises the following components in mass / volume ratio: 0.01 to 8 percent of polysaccharide with anionic groups, 0.0000001 to 1 percent of functional polypeptide with positive charge groups, and 0.05 to 5 percent of polysaccharide with cationic groups or cationic polymerized polypeptide or mixture of the two in any ratio. The invention also provides a preparation method for the reinforced anti-adhesion composite gel. The reinforced anti-adhesion composite gel can effectively reduce the occurrence of adhesion by adding the anti-adhesion functional polypeptide with polyelectrolyte interaction and the polysaccharide with cationic groups and / or cationic polymerized polypeptide into materials.

The invention provides a degradable metal composite plate for the cranio-maxillofacial bone restoration and a preparation method thereof. The metal composite plate comprises a layer of magnesium-basedor iron-based metal plate and two layers of zinc-based metal plates, wherein the two layers of zinc-based metal plates are respectively compounded onto the two surfaces of the magnesium-based or iron-based metal plate to form a zinc-magnesium-zinc three-layer metal composite plate or a zinc-iron-zinc three-layer metal composite plate. The degradable metal composite plate for the cranio-maxillofacial bone restoration of the structure can solve the problems of poor biocompatibility, undegradability and requirement of secondary operation for taking out of a cranio-maxillofacial bone restorationmaterial in clinics. Through controlling the thickness ratio of the magnesium-based or iron-based metal plate and the zinc-based metal plate, the regulation on the metal composite degradation time canbe achieved, so that the degradation speed can better correspond to the human body restoration speed; the human body restoration speed is accelerated. By the coating lamination rolling preparation method, the zinc-based metal plate is compounded onto the surface of the magnesium-based or iron-based metal plate to form the degradable cranio-maxillofacial bone restoration material; the process treatment method is simple; the control is easy; the manufacturing cost is low.

The invention provides a cladded nuclide labeled protein microsphere, comprising the following bulk pharmaceutical chemicals and auxiliary materials in parts by weight: 1-5 parts of Na131I, 1-5 parts of Na125I, 300-1000 parts of chitosan, 100-500 parts of sodium alginate and 300-800 parts of gelatin, wherein, the specific radioactivity concentrations of the Na131I and the Na125I are both 37GBq / ml. The invention also provides a preparation method and applications of the cladded nuclide labeled protein microsphere; the cladded nuclide labeled protein microsphere adopts the inclusion of the chitosan and the sodium alginate; the actual half-life period of the cladded nuclide microsphere in the bodies of animals is longer, and is close to the half-life period of the nuclide; and the blood gamma counts and urine gamma counts of two microspheres are compared to discover that the nuclide released by the cladded nuclide microsphere is more stable than the nuclide released by the uncladded nuclide microsphere, thereby reliving the effect of the explosive release, thus the cladding can protect the nuclide microsphere, reduce the label peeling, and prolong the degrading time of the microsphere in the bodies.

The invention relates to a liquid dressing containing a chitosan derivative, comprising the following components in percentage by weight: 1-5% of CMCS (carboxymethyl chitosan), 0.1-0.5% of collagen albumen powder, 10-15% of humectant, 0.2-2% of antibacterial agent, 2-10% of penetration enhancers and the balance of deionized water. The liquid dressing is obtained by mixing the components in sequence, stirring evenly and bulking. The liquid dressing has the advantage of good biocompatibility, good antimicrobial, antiphlogistic and hemostatic effects and high biological safety, and is convenient to use.

The present invention belongs to the field of slow-release fertilizers, and specifically discloses a melon high-efficiency slow-release fertilizer with degerming insecticidal effects, the melon high-efficiency slow-release fertilizer with degerming insecticidal effects is characterized by comprising the following components in parts by weight: garlic polysaccharide sulfide derivative, attapulgite, polyvinyl alcohol, a crosslinking agent, polyglutamate hydrogel, mesoporous silica nanoparticles, salicylic acid, toosendanin, pyrethrum, tea polyphenols, composite microbial agents, sodium selenite, compound sodium nitrophenolate, viscous konjac flour, residue of furfural, brown sugar residue, and amino acids and the like. The garlic polysaccharide sulfide derivative and the attapulgite are used as basic coating materials, the micron size composite hydrogel prepared from the polyglutamate hydrogel and different sizes of mesoporous silica nanoparticle matters are added into the coating materials, the pore size of the coating materials are enriched, the dynamic slow-release performance and nutrient use efficiency of the fertilizer are improved, the fertilizer efficiency regulation property is ensured, the melon high-efficiency slow-release fertilizer promotes the melon to absorb and utilize different nutrients, and promotes the efficient cultivation.

The invention particularly relates to a collagen covalent cross-linking hydrogel and a preparation method thereof. An injectable hydrogel causes the problems of red and swollen, warty bumps and too fast absorption and the like after being used, and can not be used or can not fully meet requirements of beauty and wrinkle reduction. According to the preparation method, the Schiffbase reaction principle and the Acetalization reaction principle are utilized. By mass, 2.0%-5.0% of Dialdehyde starch solution, 2.0%-4.0% of collagen solution and 1.0%-5.0% of chitosan solution are stirred in a mixed mode with the size ratio of (1-4): (1-3): (1-3) to obtain the covalent cross-linking hydrogel. The prepared collagen covalent cross-linking hydrogel can form stable gel within a temperature range of 4-40 DEG C, and the gel takes 2-3 minutes in forming time, and is good in mechanical performance, and poor in immune rejection reaction. Degradation time of the gel is obviously prolonged and can reach about 12 months, and the gel is safer and more effective when applied to treat skin dimpling, wound trauma and wrinkles ( crows-feet and forehead wrinkles and frown lines and the like).

The invention discloses a polylactic acid compound preparation method which is as follows: under an inert atmosphere reacting a lactide monomer, an unsaturated monomer and a catalyst composition in a solvent at above 180 to 250 DEG C under airtight conditions to obtain a polylactic acid compound. According to the method, the reaction can be performed at high temperature (greater than 180 DEG C) to obtain the un-discolored crosslinked polylactic acid compound, and the technical prejudice is overcome to obtain the high molecular weight crosslinked polylactic acid compound. According to the method, by the use of the unsaturated monomer for modification of lactic acid, carbon-carbon double bonds are opened for the crosslinking reaction to obtain the crosslinked netlike polylactic acid compound, the mechanical property of the polymer modified compound can be effectively improved, and the thermal stability of the polylactic acid compound can be improved.

Belonging to the field of material preparation, the invention discloses a preparation method of a linear cross-linked hyaluronic acid. The method includes: firstly treating a hyaluronic acid raw material to reduce the molecular weight; then mixing an alkaline solution with a cross-linking agent into a mixed solution, adding the hyaluronic acid raw material into the mixed solution and performing stirring till complete dissolution, and then carrying out low temperature cross-linking reaction at 2DEG C-20DEG C for 12h-36h to form a hyaluronic acid gel; then carrying out hot alkali activation cross-linking reaction on the hyaluronic acid gel at 25DEG C-65DEG C for 1h-6.5h to form a gel; and then using PBS dialysate for dialysis treatment on the gel so as to obtain a gel paste.

The invention discloses procyanidine-modified carboxymethyl chitosan, a preparation method thereof, and application thereof in the fields of medical materials, health-care foods, cosmetics and the like. The procyanidine-modified carboxymethyl chitosan keeps the characteristics of carboxymethyl chitosan and has high oxidation resistance, antibacterial activity, barrier properties and the like, and is worthy of being applied.

A starch-based hydrogel for the controlled delivery of a biologically active agent is described. The hydrogel comprises a dispersed phase, and a dispersion medium consisting substantially of water. The dispersed phase includes a polymeric network comprising a hydrolyzable polymeric substance derived from starch, and a cross-linker. In various embodiments, the polymeric starch-derived network includes amylose, amylopectin, or a combination thereof, or soluble starch. The cross-linker is a molecule having at least two carboxyl moieties. The hyrogel is biocompatible and biodegradable, and suitable for loading with biologically active agents ranging from small molecule therapeutics to macromolecules such as proteins, polysaccharides and nucleic acids. Upon administration to a host animal, the hydrogel biodegrades, releasing as degradation products only naturally-occurring sugar molecules that are non-toxic and non-immunogenic to the host.

The invention discloses a method for preparing a marine environment-friendly calcium citrate hard tissue repair material. The method comprises the following steps of: (1) cleaning fresh oyster shells in a non-pollution sea area physicochemically, soaking the cleaned fresh oyster shells in weak acid, and washing by flowing water until impurities are removed completely; (2) crushing the clean oyster shells into granules by a ball grinding mill, and sieving with a 200-mesh sieve; (3) reacting oyster shell powder with a supersaturated solution of citric acid, centrifuging, taking precipitates out, and drying by a forced draft drying machine to obtain calcium citrate powder; and (4) filtering the prepared calcium citrate powder by using a 100-mesh filter sieve, filtering by using a 60-mesh filter sieve, and taking filtered substances out to obtain calcium citrate granules. The marine environment-friendly calcium citrate hard tissue repair material has high mechanical strength and appropriate granular sizes, and the degradation time of the material is prolonged by tight bonding force among crystals, so that the material can be degraded slowly in bodies, and calcium ions are released stably to create a local high-calcium environment; and the marine environment-friendly calcium citrate hard tissue repair material has an obvious therapeutic effect on bone loss, osteoporosis and bone tumors, and has a wide application value in biological tissue repair.

The invention relates to the technical field of contraceptive drugs, in particular to a biodegradation type long-acting subdermal contraceptive implant containing gestodene which uses the biodegradable polymer materials as the carrier for preparation and the preparation. The invention consists of the drug gestodene and the polymer biodegradable materials which are taken as a carrier (such as, trimethylene carbonate / p-Dioxanone copolymer (P(TMC-co-PDO))), a bar-shaped drug core is prepared by mixing the drug and the carrier, then the carrier materials are prepared into a drug delivery tube, then the drug core is arranged in the drug delivery tube, and the both ends are blocked by adhesives. The average daily drug delivery amount of the drug gestodene in the body is 10 to 30 micrograms. The implantation of one implant can be contraceptive for 1 to 2 years. The carrier materials can be degraded into small molecules after the release of the drug, the invention does not need to be taken out by the operation method, and the using cost is greatly reduced.

The invention relates to the field of biological material, and particularly relates to an acellular matrix tendon anti-adhesion film and a preparation method thereof. The method disclosed by the invention is characterized in that mammalian tendons are used, and an acellular matrix tendon anti-adhesion film is prepared by a process of raw material treatment, decellularization, matrix dissolution, low-temperature drying film formation, neutralization water washing, and the like. The acellular matrix tendon anti-adhesion film provided by the invention eliminates the immunogenicity of heterologousand foreign tissues, retains the active components of the tendon extracellular matrix, directly wraps a tendon injury part, provides a good microenvironment for tendon repair, prevents adhesion of tendons to surrounding tissues, and promotes tendon repair. In addition, the method for preparing the tendon anti-adhesion film has low cost.

The invention discloses a preparation method of a mineral element containing coated sustained-release basic fertilizer for paddy rice. According to the preparation method, an internal membrane material and an external membrane material are prepared in advance; then the internal membrane material is sprayed on the surface of a fertilizer core to carry out coating so as to obtain a material A; thenthe external membrane material is sprayed on the surface of the material A to carry out coating so as to obtain the basic fertilizer. The provided coated sustained-release basic fertilizer has the advantages that the nutrients of the coated sustained-release basic fertilizer are comprehensive, the fertilizing effect is long-lasting, the utilization rate is high, the water retention performance isgood, the sustained-release effect of inorganic nutrients is good, moreover, the damage of the basic fertilizer to the soil environment is small, the paddy rice yield is high, and the paddy rice quality is good.

The invention provides a degradation inhibitor of a gamma-polyglutamic acid and a gamma-polyglutamic acid water-retaining agent and an application method thereof, wherein after the gamma-polyglutamic acid or the gamma-polyglutamic acid water-retaining agent product is dried and ground, edetic acid disodium salt or tartaric acid and other degradation inhibitors are added, the mixture is added intoa light-proof and airtight composite material wrapper, is vacuum sealed and is stored at a drying low temperature position, the degradation time of the gamma-polyglutamic acid or the derivatives thereof is prolonged from 5 days to 6 months in the solution state, the degradation time is prolonged above 35 times, and the quality guarantee period of the product can reach above 24 months.

The invention discloses a high-performance TPU (Thermoplastic Polyurethane) modified thin film and a preparation method thereof and in particular relates to the technical field of preparation of TPU modified plastic. The modified thin film is prepared from the following raw materials in parts by weight: 75 parts of TPU particles, 10 parts of rubber, 2 parts of sodium potassium silicate, 3 parts ofa flame retardant, 6 parts of natural polyphenol, 15 parts of epoxy resin, 12 parts of polyester staple fibers, 6 parts of a flatting agent, 10 parts of a friction-resisting agent, 2 parts of an environment-friendly plasticizer, 7 parts of a light degradation agent and 12 parts of starch. The modified TPU thin film has the advantages of high productivity, high surface glossiness and the like; meanwhile, the modified TPU thin film also has excellent functions of high water resistance, wear resistance, moisture permeability, wind-proof performance, cold-proof performance, antibacterial performance, anti-mildew performance, warm-keeping performance, anti-ultraviolet performance and the like; the natural polyphenol added in a preparation process can be used for effectively enhancing the yellowing resistance of the thin film; a formula contains a starch material, so that the production cost can be reduced, and the degradation time is accelerated; no air pollution is caused in an incineration and combustion process and the modified TPU thin film has a good protection effect on the environment.