5results about How to "Realize instant detection" patented technology

The invention discloses a split type micro-fluidic chip and a working method thereof. In the chip, a reagent storage module is connected with a reaction module through a connection module, and the reaction module is slidably arranged in a chute of the connection module; a plurality of solution containing cavities are formed in the reagent storage module, a sealing film is attached to the top of the reaction module, and a plurality of solution overflowing cavities are formed in the reaction module; during work, the reaction module and the reagent storage module abut against each other, and when the solution containing cavity is communicated with the atmosphere, directional flowing and releasing of a solution in the solution containing cavity in the micro-fluidic chip to the solution overflowing cavity are achieved through negative pressure pumping. Sample sampling, cleaning, nucleic acid adsorption, elution and reaction in the micro-fluidic chip can be achieved, and instant detection of pathogenic microorganisms is achieved.

The invention discloses lateral flow immunochromatography test paper based on phenylboronic acid directional coupling antibody mediation and a detection method of the lateral flow immunochromatography test paper. According to the lateral flow immunochromatography test paper, the phenylboronic acid directional coupling antibody is adopted, the detection sensitivity of LFIA is improved, specific coupling is conducted on the Fc segment of the antibody, the antigen capture rate is increased, and signal amplification is achieved; meanwhile, the nano-particles are combined, and the detection line is colored by utilizing the color of the nano-particles, so that the portability and the sensitivity of the whole detection are greatly improved; the detection method based on the test paper can realize qualitative analysis on a target object by observing the color depth on the detection line with naked eyes or quantitative analysis on the content of the target object by measuring the RGB value of the detection line, has the advantages of strong specificity on the target object, high sensitivity, convenience in use, simple and rapid detection process and safe and reliable detection result, and has a great application prospect.

The invention relates to the field of cup body thickness testing, in particular to a cup body thickness compression molding process detection device and a detection method.The cup body thickness compression molding process detection device comprises sliding columns, compression columns and a cup which are arranged on a base plate, the sliding columns are arranged on the periphery of the base plate, a compression plate slides on the sliding columns jointly, and a plurality of compression shafts are arranged at the lower end of the compression plate; a pressing ring is arranged at the lower end of the pressing shaft, a pushing assembly is arranged on the base plate, an annular groove is formed in the lower end of the pressing ring, a rotating ring is rotationally arranged in the annular groove, a wiping assembly used for wiping a cup is arranged on the inner diameter of the rotating ring, and a detection unit is further arranged on the inner wall of the rotating ring; the wiping assembly automatically wipes the outer side of the cup body before detection, particle impurities are removed, the phenomenon that the impurities interfere with the detection process is avoided, and the detection unit adopts a contact detection design and is not affected by factors such as ambient light, temperature and dust.

The application discloses a kind of plate thickness and wedge-shaped edge detection device, with conveying assembly, cleaning assembly, laser detector and warning assembly;Conveying assembly is used to convey gypsum board, and the both sides of conveying assembly are provided with notch;Cleaning assembly is set to the upstream of conveying assembly, for removing water stain dust on the surface of gypsum board;Laser detector is symmetrically set to the both sides of conveying assembly, and the upper end and middle part of laser detector are respectively provided with two laser sensors and controller, and laser sensor is electrically connected to controller;Laser detector side is also provided with warning assembly, and controller can control warning assembly to send alarm when receiving abnormal signal.The application exposes the edge of gypsum board by setting notch on the side of conveying assembly, and sets laser detector at the notch, so that two laser sensors can detect the distance from the upper and lower surfaces of gypsum board when gypsum board passes through laser detector, so as to obtain the edge and thickness of gypsum board, and realize the instant detection of the edge thickness of gypsum board.

This invention relates to the field of biodetection technology, providing an enzyme cascade reaction system for the detection of nucleic acids and protein molecules, comprising BER endonuclease and Argonaute endonuclease; wherein the BER endonuclease is one or more selected from APE1, FEN1, Fpg, UDG, and T7endonuclease, and the Argonaute endonuclease is one or more selected from pfAgo, CpAgo, CbAgo, TtAgo, RasAgo, MjAgo, and NgAgo. This invention also provides a method for detecting nucleic acids and protein molecules using the above system, and the application of the above system in the preparation of target nucleic acid and target protein molecule products from detection samples. This invention utilizes the synergistic enzyme activity of APE1 and PfAgo in the enzyme cascade reaction system to achieve real-time detection of nucleic acid and protein biomarkers without pre-amplification within 45 minutes.