51results about How to "Uniform crystal particles" patented technology

The invention discloses a preparation method for a clindamycin phosphate powder injection raw medicine which comprises the steps: (a) purification is carried out on a crude product of clindamycin phosphate; (b) crystallization and crystal growth are carried out on filter liquor after the filter liquor is arranged in a crystallization tank; (c) centrifugal separation and washing are carred on crystallization liquor; (d) fast temperature raising and drying are carried out on a clindamycin phosphate wet finished product. The preparation method for the clindamycin phosphate powder injection raw medicine has the advantages of favorable water solubility, uniform crystal form particles, small specific volume, big bulk density, low solvent residue, and the like. The method also simplifies the process operation, and dramatically enhances the product yield.

The invention discloses a method for preparing a magnesium-doped xLiFePO4.yLi3V2(PO4)3 lithium ion battery anode material, and relates to a method for preparing a lithium ion battery anode material. The method solves the problems of bad existence environment and high cost of prior lithium ion anode materials under the condition that the cycle performance of the lithium ion anode materials is ensured not to reduce. The method comprises the following steps of: weighing lithium source, iron source, vanadium salt, magnesium salt, phosphoric acid source and carbon source, mixing, and performing wet milling, pre-sintering and calcination to obtain the xLiFePO4.yLi3V2(PO4)3. The process is simple. The anode material prepared by the method has good magnification discharge performance; and during 10C discharge, the discharge specific capacity is 90mAh / g, and the capacity is nearly not attenuated after 20 times of cycles.

The invention discloses a dual-core cage-shaped earth samarium (III) organic complex, and a preparation method and application thereof. The complex adopts o-chlorobenzoic acid as a main ligand and 1,10-phenanthroline as an auxiliary ligand, and has a dual-core cage-shaped structure; the preparation method is characterized by adopting the o-chlorobenzoic acid, samarium salt and the 1,10-phenanthroline as raw materials, synthesizing through a solvent method, and obtaining an Sm2(C7H5OClCOO)6(C12H8N2)2 crystal through self-volatilization crystallization. The preparation method is simple to operate, moderate in reaction condition, high in product yield, and uniform in crystal particles; the earth samarium (III) organic complex is stable in structure, is used as a catalyst to be applied to catalyzing binary acid and polyhydric alcohols for carrying out esterification reaction to prepare an alkyd resin, and shows excellent catalytic activity.

The invention discloses a method for refining cefpiramide acid, and belongs to the technical field of medicines. The method comprises the following steps: A, putting crude cefpiramide acid into a solvent 1, adding a transaminating agent, stirring and dissolving the mixture to clarification, so as to obtain a cefpiramide salt solution; B, adding a decolorizing agent into the cefpiramide salt solution, filtering and collecting filtrate; C, controlling the filtrate temperature to be 10-20 DEG C, adding a dissolution agent, filtering and collecting a solid crystal; D, putting the solid crystal into a solvent 2, controlling the temperature to be 10-15 DEG C, adding an acidic reagent to adjust the pH value to 2.0-3.0, adding a seed crystal, crystallizing, filtering and collecting the solid crystal of cefpiramide acid and mother liquor; and E, washing the solid crystal of cefpiramide acid and drying to obtain refined cefpiramide acid. The cefpiramide acid prepared with the method is high in purity, few in impurities and low in color grade; and the refining method provided by the invention has the advantages of being simple in process, environmentally friendly, and suitable for large-scaleindustrial production, saving energy, and the like.

The invention relates to a device and method for continuous preparation of lithium hexafluorophosphate. The device comprises a continuous evaporation crystallizer, a condensation recoverer, a heater, an ex-situ circulation pump, a product crystal delivery pump and a separation apparatus. Specifically, the continuous evaporation crystallizer is internally equipped with a stirrer, and the lower part of the continuous evaporation crystallizer is equipped with an elutriating leg; the ex-situ circulation pump, the heater, and the continuous evaporation crystallizer are connected in order; the elutriating leg is connected to the product crystal delivery pump; the product crystal delivery pump is connected to the separation apparatus; and the condensation recoverer is connected to the upper part of the continuous evaporation crystallizer. The invention employs an effective evaporative crystallization method and the advanced DBT type continuous efficient evaporation crystallizer to make the crystalline particles of lithium hexafluorophosphate more uniform, and effectively lowers the product investment cost and energy consumption per ton, thus realizing continuous, efficient and large-scale production of lithium hexafluorophosphate.

The invention provides a carbon steel surface treatment method. The carbon steel surface treatment method comprises the following steps: the surface shot blasting treatment is performed on carbon steel; and the surface of the shot-blasted carbon steel is blackened. Compared with the prior art, the carbon steel surface treatment method effectively combines the surface shot blasting with the blackening treatment; as the shot blasting treatment is firstly performed on the surface of the carbon steel, crystal particles of blackening films formed by subsequent blackening treatment are fine, uniformand compact; through the shot blasting treatment, the self-corrosion potential of the blackening films is improved, and the self-corrosion current density is reduced; and meanwhile, through the shotblasting treatment, the resistance of the blackening films is increased, and the saline immersion resistance is higher. As the shot blasting treatment is performed before the blackening treatment, thecorrosion resistance of the prepared blackening films can be improved.

The invention discloses a method for purifying cefepime hydrochloride, belonging to the field of chemical pharmacy, using cefepime hydrochloride arginine as a raw material, adding a complexing agent to a solution of cefepime hydrochloride arginine, decolorizing, and then adding Adding a dispersant and a crystallizer to the decolorizing solution for crystallization to obtain cefepime hydrochloride; the invention can fully recycle cefepime hydrochloride arginine that does not meet the quality standards, and the prepared cefepime hydrochloride has a content of It has the advantages of high concentration, less impurities and good stability, simple preparation method, energy saving and environmental protection, and is suitable for large-scale industrial production.

The invention discloses an industrial antimony trioxide production device which comprises a reaction furnace, an air blowing pipe, a crystallization pipe and a collection chamber, a metal antimony feeding port is formed in one side of the reaction furnace, a rotation starting assembly, a movable crystallization cover and a control rod are arranged in the crystallization pipe from bottom to top, and the control rod is connected with the top of the movable crystallization cover and the top of the crystallization pipe. The antimony trioxide production device is used for producing antimony trioxide, furnace gas with saturated antimony trioxide concentration is obtained through the movable crystallization cover and then is crystallized, the crystallization efficiency can be effectively improved, crystal particles are kept uniform, and the stability of product quality is kept; and the crystallization efficiency and the lens particle uniformity are also improved by two different inner and outer rotational flows in the movable crystallization cover.

The invention discloses a copper coordination polymer. The polymer comprises a repeating structural unit of formula I: the polymer has a multi-nuclear structure, and the molecular structure of the polymer is stable; the invention also discloses a preparation method of the polymer, Add 2,2′-biphenyldicarboxylic acid, copper salt, 3-(2-pyridyl)-1,2,4-triazole to the mixture of organic components and water, and adjust the pH value to 4-8 , react, and place it at room temperature after the reaction, and the polymer synthesized by this method has the advantages of simple method, convenient purification, high yield, and good stability in air; the present invention also discloses the crystal of the polymer, and the present invention The polymer is used in the preparation of antiferromagnetic materials and antibacterial drugs.