Nasal cavity slow-release dosing device

Abstract

The invention belongs to the field of nasal cavity dosing and therapeutic equipment, and particularly relates to a nasal cavity slow-release dosing device. The nasal cavity slow-release dosing devicecomprises a fixing frame, a liquid storage balloon, a capillary tube and a contact, wherein the liquid storage balloon is arranged on the fixing frame, the fixing frame is provided with the contact, the liquid storage balloon is connected with the contact through the capillary tube, the fixing frame is a clamp structure capable of fixing the liquid storage balloon on the nasal septum, the liquid storage balloon is provided with a dosing hole, and the dosing hole is provided with a hole plug. The nasal cavity slow-release dosing device has the advantages that drugs can be continuously and slowly released into the nasal cavity and have a therapeutic effect through the nasal cavity, so that patients accept the device more easily, and the therapeutic effect is good.

Description

technical field

[0001] The invention belongs to the field of nasal cavity drug delivery treatment equipment, in particular to a nasal cavity sustained release drug delivery device. Background technique

[0002] The nose is the initial part of the respiratory passage and also an olfactory organ. It consists of three parts: the external nose, nasal cavity and paranasal sinuses. It is composed of nasal bones, nasal cartilage, nasal muscles and covering skin. The nasal cavity is divided into left and right chambers by the nasal septum. The nostrils communicate with the outside world at the front, and the nasopharynx at the rear. The inner surface of the nasal cavity is the mucous membrane with a surface area of ​​up to 150 cm 2 , and shows that there are a large number of microvilli, and the lower layer is rich in capillaries and lymphatic capillaries, which is an ideal drug delivery route. The nasal mucosa drug delivery preparation has the following advantages:

[0003] 1. Hi...

Examples

Embodiment 1

[0031] Such as figure 1 In the shown nasal cavity sustained-release drug delivery device, the fixed frame 1 is arranged at the nasal septum, and the fixed frame 1 is clip-shaped, including a left clip 101, a right clip 102, a spring 103, a circlip 104 and a pin 105; The intersecting part of the left clip 101 and the right clip 102 is provided with a liquid storage bag 2, and the liquid storage bag 2 is in the shape of a round cake, and the two wings of the left clip 101 and the right clip 102 are respectively provided with contact 3 , the reservoir 2 passes through the capillary and contact 3 connect.

[0032] Add liquid medicine through the dosing hole of the liquid storage bag 2, plug the hole plug; clamp the transfusion device on the nasal septum through the clip-shaped fixing frame of the left clip 101, the right clip 102, the spring 103, the circlip 104 and the pin 105, left and right 2 contact 3 Plug the nostrils to help filter the air and dialysis the medicine. T...

Embodiment 2

[0036] Such as figure 2 As shown, the fixed frame 1 is arranged on the nasal septum, and the fixed frame 1 is n-shaped or "several"-shaped, and the top of the n-shaped or "several"-shaped fixed frame 1 is provided with a liquid storage bag 2, and the liquid storage bag 2 is wrapped in strips on the top of the n-shaped or "several"-shaped fixing frame, and the liquid storage bag 2 is connected to the contact 3 through a capillary. The n-type or "several"-shaped fixed frame is made of hard plastic or metal material with certain yield strength, such as steel.

[0037] Add liquid medicine through the dosing hole of the liquid storage bag 2, plug the hole plug; extend the contact 3 into the nostril, plug the nostril, the liquid medicine enters the nasal cavity from the liquid storage bag 2 through the capillary, and the contact 3 The channel can play the role of ventilation, as well as sterilize and filter the air.

[0038] When the liquid storage bag 2 is a double-layered cavit...

Embodiment 3

[0041] Such as image 3 As shown, the contact 3 is in the shape of a truncated cone, with one or more straight channels arranged in the center, and the surroundings are made of cotton, polyethylene or chemical fiber materials.

technical field

[0001] The invention belongs to the field of nasal cavity drug delivery treatment equipment, in particular to a nasal cavity sustained release drug delivery device. Background technique

[0002] The nose is the initial part of the respiratory passage and also an olfactory organ. It consists of three parts: the external nose, nasal cavity and paranasal sinuses. It is composed of nasal bones, nasal cartilage, nasal muscles and covering skin. The nasal cavity is divided into left and right chambers by the nasal septum. The nostrils communicate with the outside world at the front, and the nasopharynx at the rear. The inner surface of the nasal cavity is the mucous membrane with a surface area of ​​up to 150 cm 2 , and shows that there are a large number of microvilli, and the lower layer is rich in capillaries and lymphatic capillaries, which is an ideal drug delivery route. The nasal mucosa drug delivery preparation has the following advantages:

[0003] 1. Hi...

Examples

Embodiment 1

[0031] Such as figure 1 In the shown nasal cavity sustained-release drug delivery device, the fixed frame 1 is arranged at the nasal septum, and the fixed frame 1 is clip-shaped, including a left clip 101, a right clip 102, a spring 103, a circlip 104 and a pin 105; The intersecting part of the left clip 101 and the right clip 102 is provided with a liquid storage bag 2, and the liquid storage bag 2 is in the shape of a round cake, and the two wings of the left clip 101 and the right clip 102 are respectively provided with contact 3 , the reservoir 2 passes through the capillary and contact 3 connect.

[0032] Add liquid medicine through the dosing hole of the liquid storage bag 2, plug the hole plug; clamp the transfusion device on the nasal septum through the clip-shaped fixing frame of the left clip 101, the right clip 102, the spring 103, the circlip 104 and the pin 105, left and right 2 contact 3 Plug the nostrils to help filter the air and dialysis the medicine. T...

Embodiment 2

[0036] Such as figure 2 As shown, the fixed frame 1 is arranged on the nasal septum, and the fixed frame 1 is n-shaped or "several"-shaped, and the top of the n-shaped or "several"-shaped fixed frame 1 is provided with a liquid storage bag 2, and the liquid storage bag 2 is wrapped in strips on the top of the n-shaped or "several"-shaped fixing frame, and the liquid storage bag 2 is connected to the contact 3 through a capillary. The n-type or "several"-shaped fixed frame is made of hard plastic or metal material with certain yield strength, such as steel.

[0037] Add liquid medicine through the dosing hole of the liquid storage bag 2, plug the hole plug; extend the contact 3 into the nostril, plug the nostril, the liquid medicine enters the nasal cavity from the liquid storage bag 2 through the capillary, and the contact 3 The channel can play the role of ventilation, as well as sterilize and filter the air.

[0038] When the liquid storage bag 2 is a double-layered cavit...

Embodiment 3

[0041] Such as image 3 As shown, the contact 3 is in the shape of a truncated cone, with one or more straight channels arranged in the center, and the surroundings are made of cotton, polyethylene or chemical fiber materials.

Images