Glycosylated protein sensor, assay method, program, and sensor manufacturing method

CN112292446BActive Publication Date: 2025-02-28PROVIGATE KK
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Patent Information

Application Number
CN201980041212.5
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Priority Date
2018-05-18
Filing Date
2019-05-17
Publication Date
2025-02-28
Estimated Expiration
2039-07-28

AI Technical Summary

Technical Problem

In the existing glycated protein assay, the coexistence of protease and ketoamine oxidase leads to difficult control of the enzyme decomposition reaction, resulting in low measurement accuracy, slow speed and easy to produce measurement errors.

Method used

Immobilized protease and ketone amine oxidase are used to combine with hydrogen peroxide detection part to form an integrated sensor system. Through immobilization technology, the enzyme's decomposition and activity decrease are prevented, and the measurement efficiency and accuracy are improved.

Benefits of technology

High-precision and rapid glycated protein assays are achieved, which reduces measurement errors, and reduces operating costs by immobilizing enzymes, improving the sensitivity and reusability of the sensor.

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Abstract

The present invention provides a glycated protein sensor comprising an immobilized protease, an immobilized ketoamine oxidase and a hydrogen peroxide detection unit.
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Citation Information

Patent Citations

  • Multilayer reagent test strips and methods for using the same to quantify glycated protein in a physiological sample

    US20030211564A1

  • HEMOGLOBIN A1c SENSOR

    WO2007094354A1