Fluid System

Abstract

The present invention relates to the field of fluid transport technology, and in particular to a fluid system, which includes a fluid container for storing fluid; a control valve group, including a primary valve group and multiple secondary valve groups, each of which is connected to the primary valve group and the fluid container; a flow pool, wherein the flow pool is connected to the outlet of the primary valve group via a common pipeline; a first power module, wherein the first power module is connected to the outlet of the flow pool, and the outlet of the first power module is connected to a waste liquid container and / or the fluid container; and a second power module, wherein the second power module is connected to the bypass port of the primary valve group via a bypass pipeline, and the outlet of the second power module is connected to the waste liquid container and / or the fluid container. The present invention can reduce waste caused by fluid replacement while improving flexibility.

Description

Technical Field

[0001] The present invention relates to the technical field of fluid transportation, and in particular to a fluid system. Background Art

[0002] Using the flow cell as the reaction chamber, a fluid system needs to be designed to serve it, which is used to transport samples, reagents, water, cleaning agents or fluids with other functions into the flow cell. At the same time, the above-mentioned fluids used in the flow cell can be transported to a waste liquid container for disposal, or transported to other containers for recycling and reuse.

[0003] The classic design in existing technology is the direct flush fluid system. This design requires only a common pipeline at the inlet of the flow cell for the inflow of all types of fluids. If the flow cell uses multiple different fluids, valves or a combination of valves can be used to connect the pipelines carrying different fluids to the common pipeline. A power module can then drive the fluids through the valves and the common pipeline into the flow cell.

[0004] The first problem with this design is the waste caused by fluid replacement. The flow rate required to replace the fluid in the common pipe and flow pool is proportional to the internal volume of the flow space. Only the fluid that eventually fills the flow pool is effectively used, while the part of the fluid previously consumed for replacement of the common pipe and flow pool is wasted. The second problem is the flow pool's restrictions on fluid use. During the use of the flow pool, other pipelines cannot be cleaned, making it impossible to prepare for the next fluid that needs to flow into the flow pool, resulting in poor flexibility in fluid transportation.

[0005] Therefore, a fluid system is needed to solve the above problems. Summary of the Invention

[0006] The object of the present invention is to provide a fluid system that can reduce waste caused by fluid replacement while improving flexibility.

[0007] To achieve this object, the present invention adopts the following technical solutions:

[0008] Fluid systems, including:

[0009] a fluid container for storing fluid;

[0010] A control valve group, comprising a primary valve group and multiple secondary valve groups, wherein the multiple secondary valve groups are all in communication with the primary valve group and the fluid container;

[0011] a flow pool, the flow pool being connected to the outlet of the primary valve group via a common pipeline;

[0012] a first power module, wherein the first power module is in communication with an outlet of the flow cell, and the outlet of the first power module is in communication with a waste liquid container and / or the fluid container;

[0013] a second power module, the second power module being in communication with a bypass port of the primary valve assembly via a bypass pipe, and an outlet of the second power module being in communication with the waste liquid container and / or the fluid container;

[0014] The primary valve group is configured such that: one of the secondary valve groups is communicated with the common pipeline, and the remaining part or all of the secondary valve groups are communicated with the bypass pipeline.

[0015] Furthermore, a plurality of mutually unconnected liquid storage cavities are provided in the fluid container, and the plurality of liquid storage cavities are used to store different fluids.

[0016] Furthermore, the secondary valve group is communicated with one or more of the liquid storage chambers.

[0017] Furthermore, the flow pool has a plurality of channels that are not connected to each other, and the plurality of channels are all connected to the outlet of the flow pool, and the outlet of the primary valve group is connected to each of the channels.

[0018] Furthermore, two secondary valve groups are provided, and the two secondary valve groups are respectively connected to the first port and the second port of the primary valve group, the third port of the primary valve group is connected to the common pipeline, and the fourth port of the primary valve group is connected to the bypass pipeline. The primary valve group can connect the first port with the third port, the second port with the fourth port, or the first port with the fourth port, and the second port with the third port.

[0019] Furthermore, the primary valve group is a four-way reversing valve, a two-position four-way solenoid valve or a two-position four-way selection valve.

[0020] Furthermore, the primary valve group includes a first two-position three-way solenoid valve, a second two-position three-way solenoid valve, and a third two-position three-way solenoid valve, two bypass pipes are provided, and the secondary valve group includes a first selection valve and a second selection valve, one end of the first selection valve and the second selection valve are both connected to the fluid container, the other end of the first selection valve is connected to the first port of the first two-position three-way solenoid valve, the second port of the first two-position three-way solenoid valve is connected to one of the bypass pipes, the other end of the second selection valve is connected to the first port of the second two-position three-way solenoid valve, the second port of the second two-position three-way solenoid valve is connected to another of the bypass pipes, the third port of the first two-position three-way solenoid valve is connected to the first port of the third two-position three-way solenoid valve, the third port of the second two-position three-way solenoid valve is connected to the second port of the third two-position three-way solenoid valve, and the third port of the third two-position three-way solenoid valve is connected to the common pipe.

[0021] Furthermore, the first power module and the second power module are both injection pumps.

[0022] Furthermore, it also includes a first waste liquid pipeline and a first filling liquid pipeline, one end of the first waste liquid pipeline and the first filling liquid pipeline are both connected to the outlet of the first power module, the other end of the first waste liquid pipeline is connected to the waste liquid container, and the other end of the first filling liquid pipeline is connected to the fluid container.

[0023] Furthermore, it also includes a second waste liquid pipe and a second filling liquid pipe, one end of the second waste liquid pipe and the second filling liquid pipe are both connected to the outlet of the second power module, the other end of the second waste liquid pipe is connected to the waste liquid container, and the other end of the second filling liquid pipe is connected to the fluid container.

[0024] Beneficial effects of the present invention:

[0025] The present invention provides a fluid system in which a fluid container is used to store fluid. A primary valve group is disposed between a secondary valve group and a flow pool. A first power module is connected to the flow pool and can drive fluid flow into a waste liquid container and / or a fluid container. A second power module is connected to the primary valve group via a bypass pipe and can drive fluid through the bypass pipe into the waste liquid container and / or the fluid container. The primary valve group can connect one of the secondary valve groups to a common pipe, while the remaining part or all of the secondary valve groups are connected to the bypass pipe. Since the distance between the primary valve group and the flow pool is short, waste caused by fluid replacement can be reduced. When the secondary valve group connected to the flow pool is supplying fluid, the remaining secondary valve groups can perform pipeline cleaning or fluid preparation through the bypass pipe. When fluid switching is required, only the primary valve group needs to be controlled to complete the switching of the secondary valve groups. While the fluid is being delivered to the flow pool, the remaining secondary valve groups can perform cleaning operations and fluid supply preparation operations, which can improve the flexibility and efficiency of fluid supply. BRIEF DESCRIPTION OF THE DRAWINGS

[0026] Figure 1 is a schematic diagram of a fluid system of the present invention;

[0027] Figure 2 It is a principle diagram of a fluid system of the present invention;

[0028] Figure 3 is another schematic diagram of a fluid system of the present invention;

[0029] Figure 4 is another schematic diagram of a fluid system of the present invention;

[0030] Figure 5 is yet another schematic diagram of a fluid system of the present invention;

[0031] Figure 6 This is a principle diagram of a fluid system according to the present invention in which three secondary valve groups are arranged.

[0032] In the picture:

[0033] 1. Fluid container; 2. Secondary valve group; 21. First selection valve; 22. Second selection valve; 23. Branch channel; 3. Primary valve group; 31. First two-position three-way solenoid valve; 32. Second two-position three-way solenoid valve; 33. Third two-position three-way solenoid valve; 34. Common pipeline; 35. Bypass pipeline; 4. Flow pool; 41. Channel; 5. First power module; 51. First waste liquid pipeline; 52. First filling liquid pipeline; 6. Second power module; 61. Second waste liquid pipeline; 62. Second filling liquid pipeline; 7. Waste liquid container. DETAILED DESCRIPTION

[0034] The technical solution of the present invention is further described below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely for the purpose of explaining the present invention and are not intended to limit the present invention. It should also be noted that, for ease of description, the accompanying drawings only show portions relevant to the present invention, not all of them.

[0035] In the description of the present invention, it should be noted that, unless otherwise expressly specified or limited, the terms "mounted," "connected," and "connected" should be understood broadly. For example, they may refer to fixed or detachable connections; mechanical or electrical connections; direct or indirect connections through an intermediary; and internal communication between two components. Those skilled in the art will understand the specific meanings of the above terms in the present invention.

[0036] In the present invention, unless otherwise expressly specified or limited, a first feature being "above" or "below" a second feature may include the first and second features being in direct contact, or may include the first and second features being in contact not directly but through another feature between them. Furthermore, a first feature being "above," "above," and "above" a second feature may include the first feature being directly above or obliquely above the second feature, or may simply mean that the first feature is higher in level than the second feature. A first feature being "below," "below," and "below" a second feature may include the first feature being directly below or obliquely below the second feature, or may simply mean that the first feature is lower in level than the second feature.

[0037] Using the flow cell as the reaction chamber, a fluid system needs to be designed to serve it, which is used to transport samples, reagents, water, cleaning agents or fluids with other functions into the flow cell. At the same time, the above-mentioned fluids used in the flow cell can be transported to a waste liquid container for disposal, or transported to other containers for recycling and reuse.

[0038] In order to reduce the waste caused by fluid replacement and improve flexibility, such as Figures 1-6 As shown, the present invention provides a fluid system, which includes a fluid container 1 , a control valve group, a flow cell 4 , a first power module 5 , and a second power module 6 .

[0039] Among them, the fluid container 1 is used to store fluid; the control valve group includes a primary valve group 3 and multiple secondary valve groups 2, and the multiple secondary valve groups 2 are all connected to the primary valve group 3 and the fluid container 1; the flow pool 4 is connected to the outlet of the primary valve group 3 through a common pipe 34; the first power module 5 is connected to the outlet of the flow pool 4, and the outlet of the first power module 5 is connected to the waste liquid container 7 and / or the fluid container 1; the second power module 6 is connected to the bypass port of the primary valve group 3 through a bypass pipe 35, and the outlet of the second power module 6 is connected to the waste liquid container 7 and / or the fluid container 1; the primary valve group 3 is configured as follows: one of the secondary valve groups 2 is connected to the common pipe 34, and the remaining part or all of the secondary valve groups 2 are connected to the bypass pipe 35.

[0040] Because the distance between the primary valve group 3 and the flow pool 4 is relatively short, waste caused by fluid replacement can be reduced. When the secondary valve group 2 connected to the flow pool 4 is supplying fluid, the remaining secondary valve groups 2 can be used for pipeline cleaning or fluid preparation through the bypass pipe 35. When fluid switching is required, it is only necessary to control the primary valve group 3 to complete the switching of the secondary valve group 2. While the fluid is being delivered to the flow pool 4, the remaining secondary valve groups 2 can be cleaned and prepared for fluid supply, which can improve the flexibility and efficiency of fluid supply.

[0041] Furthermore, the fluid container 1 is provided with multiple, unconnected liquid storage chambers, each used to store different fluids. This allows for storage of various reagents, pure water, detergents, and the like. While one secondary valve assembly 2 is delivering a reagent, the remaining secondary valve assemblies 2 can clean the bypass conduit 35 and primary valve assembly 3 with detergent, followed by pure water, completing the cleaning process. Simultaneously, various reagents can be pumped into the remaining valve assemblies to prepare for fluid delivery.

[0042] Furthermore, the secondary valve assembly 2 is connected to one or more of the liquid storage chambers. Through this arrangement, when the secondary valve assembly 2 is connected to one of the liquid storage chambers, a single reagent can be directly supplied. When the secondary valve assembly 2 is connected to multiple liquid storage chambers, different reagents can be configured and supplied as needed. Alternatively, after supplying one reagent, a cleaning agent and pure water can be used through the bypass pipe 35 and the second power module 6 to perform a cleaning operation in preparation for the delivery of a different reagent. This approach improves the flexibility of reagent supply and simultaneously improves supply efficiency.

[0043] Furthermore, the flow cell 4 has multiple, unconnected channels 41, each of which is connected to the outlet of the flow cell 4. The outlet of the secondary valve assembly 2 is connected to each channel 41. Specifically, the number of first power modules 5 is adjusted based on the number of channels 41 to ensure fluid flow in each channel 41. By providing multiple channels 41, the secondary valve assembly 2, which is connected to the common pipeline 34, can simultaneously supply reagents to multiple channels 41, thereby improving the efficiency of the test.

[0044] Further, illustratively, there are two secondary valve groups 2. In this embodiment, the secondary valve groups 2 are selection valves. The two secondary valve groups 2 are connected to the first port and the second port of the primary valve group 3 respectively. The third port of the primary valve group 3 is connected to the common pipe 34. The fourth port of the primary valve group 3 is connected to the bypass pipe 35. The primary valve group 3 can connect the first port with the third port, the second port with the fourth port, or the first port with the fourth port, and the second port with the third port. By controlling the primary valve group 3, switching between the two secondary valve groups 2 can be achieved. When one of the secondary valve groups 2 supplies fluid, the other secondary valve group 2 can perform cleaning and preparation operations for another reagent. Further, in this example, the primary valve group 3 is a four-way reversing valve, a two-position four-way solenoid valve, or a two-position four-way selection valve.

[0045] Further, exemplarily, the primary valve group 3 includes a first two-position three-way solenoid valve 31, a second two-position three-way solenoid valve 32, and a third two-position three-way solenoid valve 33, and two bypass pipes 35 are provided. The secondary valve group 2 includes a first selector valve 21 and a second selector valve 22, one end of the first selector valve 21 and the second selector valve 22 are both connected to the fluid container 1, the other end of the first selector valve 21 is connected to the first port of the first two-position three-way solenoid valve 31, the second port of the first two-position three-way solenoid valve 31 is connected to one of the bypass pipes 35, the other end of the second selector valve 22 is connected to the first port of the second two-position three-way solenoid valve 32, the second port of the second two-position three-way solenoid valve 32 is connected to another of the bypass pipes 35, the third port of the first two-position three-way solenoid valve 31 is connected to the first port of the third two-position three-way solenoid valve 33, the third port of the second two-position three-way solenoid valve 32 is connected to the second port of the third two-position three-way solenoid valve 33, and the third port of the third two-position three-way solenoid valve 33 is connected to the common pipe 34. By controlling the first 2-position 3-way solenoid valve 31, the second 2-position 3-way solenoid valve 32, and the third 2-position 3-way solenoid valve 33, one secondary valve assembly 2 can simultaneously supply fluid to the flow cell 4 while the other secondary valve assembly 2 performs cleaning and reagent supply preparation operations. In this embodiment, the secondary valve assembly 2 can also be replaced by three three-way reversing valves or three 2-position 3-way selector valves, without further limitation.

[0046] Furthermore, both the first power module 5 and the second power module 6 are syringe pumps. When in use, the first power module 5 can be configured according to the number of channels 41 provided. The first power module 5 can use a single pump body and multiple pump ports corresponding to the number of channels 41 to achieve simultaneous control of the fluid in the channels 41; or multiple first power modules 5 can be configured corresponding to the number of channels 41 to achieve precise control.

[0047] Furthermore, the fluid system includes a first waste liquid pipeline 51 and a first filling liquid pipeline 52. One end of each of the first waste liquid pipeline 51 and the first filling liquid pipeline 52 is connected to the outlet of the first power module 5. The other end of the first waste liquid pipeline 51 is connected to the waste liquid container 7, and the other end of the first filling liquid pipeline 52 is connected to the fluid container 1. As the fluid continues to flow into the flow cell 4, the waste liquid in the flow cell 4 can enter the waste liquid container 7 through the first waste liquid pipeline 51 for collection, or enter the fluid container 1 through the first filling liquid pipeline 52 for recovery.

[0048] Furthermore, the fluid system includes a second waste liquid pipeline 61 and a second filling liquid pipeline 62. One end of each of the second waste liquid pipeline 61 and the second filling liquid pipeline 62 is connected to the outlet of the second power module 6. The other end of the second waste liquid pipeline 61 is connected to the waste liquid container 7, and the other end of the second filling liquid pipeline 62 is connected to the fluid container 1. When the fluid passes through the secondary valve assembly 2 to clean the bypass pipeline 35, the cleaned waste liquid can enter the waste liquid container 7 through the second waste liquid pipeline 61 for collection, or enter the fluid container 1 through the second filling liquid pipeline 62 for recovery.

[0049] Furthermore, the fluid system also includes multiple branch channels 23, which are arranged in a one-to-one correspondence with multiple secondary valve groups 2, and one end of the branch channel 23 is connected to the secondary valve group 2, and the other end of the branch channel 23 is connected to the waste liquid container 7.

[0050] Furthermore, after the reagent is used up, the reagent kit can also serve as a container for storing waste liquid. After the cleaning waste liquid is discharged into the reagent kit, the reagent kit becomes obsolete.

[0051] Furthermore, if Figure 6 As shown, in this embodiment, three secondary valve groups 2 are provided. In other embodiments, the number of secondary valve groups 2 can be arranged as needed, and no excessive restrictions are made here.

[0052] The fluid system provided by this embodiment has the following beneficial effects:

[0053] 1. It is possible to control the consumption of reagent replacement in the common pipeline 34 to ensure the economy of fluid operation in the fluid system.

[0054] 2. Ability to quickly transport samples or reagents to the flow cell 4 to ensure the flexibility of the fluid system timing;

[0055] 3. While transporting samples or reagents, some pipelines of the fluid system can be deep cleaned in turn to reduce cross contamination and reagent residue caused by transporting different reagents through instrument pipelines.

[0056] Obviously, the above embodiments of the present invention are merely examples for the purpose of clearly illustrating the present invention, and are not intended to limit the embodiments of the present invention. Those skilled in the art will appreciate that other variations or modifications can be made based on the above description. It is not necessary and impossible to enumerate all embodiments here. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of the present invention shall be included within the scope of protection of the claims of the present invention.

Claims

1. Fluid system, characterized in that include: A fluid container (1), wherein the fluid container (1) is used to store fluid; A control valve group, comprising a primary valve group (3) and a plurality of secondary valve groups (2), wherein the plurality of secondary valve groups (2) are all in communication with the primary valve group (3) and the fluid container (1); a flow pool (4), the flow pool (4) being in communication with the outlet of the primary valve group (3) via a common pipe (34); a first power module (5), the first power module (5) being in communication with an outlet of the flow cell (4), the outlet of the first power module (5) being in communication with a waste liquid container (7) and / or the fluid container (1); a second power module (6), the second power module (6) being in communication with the bypass port of the primary valve group (3) via a bypass pipe (35), and the outlet of the second power module (6) being in communication with the waste liquid container (7) and / or the fluid container (1); The primary valve group (3) is configured as follows: one of the secondary valve groups (2) is connected to the common pipe (34), and the remaining part or all of the secondary valve groups (2) are connected to the bypass pipe (35). When the secondary valve group connected to the flow pool supplies fluid, the remaining secondary valve groups can perform pipe cleaning or fluid preparation through the bypass pipe. When it is necessary to switch the fluid, it is only necessary to control the primary valve group to complete the switching of the secondary valve group.

2. The fluid system according to claim 1, characterized in that The fluid container (1) is provided with a plurality of mutually unconnected liquid storage cavities, and the plurality of liquid storage cavities are used to store different fluids.

3. The fluid system according to claim 2, characterized in that The secondary valve group (2) is in communication with one or more of the liquid storage chambers.

4. The fluid system according to claim 1, wherein: The flow pool (4) has a plurality of channels (41) that are not connected to each other, and the plurality of channels (41) are all connected to the outlet of the flow pool (4), and the outlet of the first-level valve group (3) is connected to each of the channels (41).

5. The fluid system according to claim 1, wherein: Two secondary valve groups (2) are provided, and the two secondary valve groups (2) are respectively connected to the first port and the second port of the primary valve group (3), the third port of the primary valve group (3) is connected to the common pipe (34), and the fourth port of the primary valve group (3) is connected to the bypass pipe (35). The primary valve group (3) can connect the first port with the third port and the second port with the fourth port, or the first port with the fourth port and the second port with the third port.

6. The fluid system according to claim 5, characterized in that The primary valve group (3) is a four-way reversing valve, a two-position four-way solenoid valve or a two-position four-way selection valve.

7. The fluid system according to claim 1, wherein: The primary valve group (3) comprises a first two-position three-way solenoid valve (31), a second two-position three-way solenoid valve (32), and a third two-position three-way solenoid valve (33); two bypass pipes (35) are provided; the secondary valve group (2) comprises a first selection valve (21) and a second selection valve (22); one end of each of the first selection valve (21) and the second selection valve (22) is communicated with the fluid container (1); the other end of the first selection valve (21) is communicated with the first port of the first two-position three-way solenoid valve (31); the second port of the first two-position three-way solenoid valve (31) is communicated with one of the The bypass pipe (35) is connected, the other end of the second selector valve (22) is connected to the first port of the second two-position three-way solenoid valve (32), the second port of the second two-position three-way solenoid valve (32) is connected to another one of the bypass pipes (35), the third port of the first two-position three-way solenoid valve (31) is connected to the first port of the third two-position three-way solenoid valve (33), the third port of the second two-position three-way solenoid valve (32) is connected to the second port of the third two-position three-way solenoid valve (33), and the third port of the third two-position three-way solenoid valve (33) is connected to the common pipe (34).

8. The fluid system according to claim 1, wherein: The first power module (5) and the second power module (6) are both injection pumps.

9. The fluid system according to claim 1, wherein: It also includes a first waste liquid pipeline (51) and a first filling liquid pipeline (52), one end of each of the first waste liquid pipeline (51) and the first filling liquid pipeline (52) is connected to the outlet of the first power module (5), the other end of the first waste liquid pipeline (51) is connected to the waste liquid container (7), and the other end of the first filling liquid pipeline (52) is connected to the fluid container (1).

10. The fluid system according to claim 1, wherein: It also includes a second waste liquid pipeline (61) and a second filling liquid pipeline (62), one end of each of the second waste liquid pipeline (61) and the second filling liquid pipeline (62) is connected to the outlet of the second power module (6), the other end of the second waste liquid pipeline (61) is connected to the waste liquid container (7), and the other end of the second filling liquid pipeline (62) is connected to the fluid container (1).

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