A strain of Lactobacillus crispatus NCU-13 and its application

By using Lactobacillus curling NCU-13 and its metabolites, the vaginal probiotic sanitary napkins are activated and proliferated, and the growth of pathogenic bacteria is inhibited, and the high recurrence and drug resistance of bacterial vaginitis treatment in the prior art is solved, and the recovery and healthy maintenance of vaginal microecology are achieved.

CN118272256BActive Publication Date: 2025-03-18THANKCOME BIOLOGICAL SCI & TECH CO LTD
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Patent Information

Application Number
CN202410305155.X
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2024-03-18
Publication Date
2025-03-18
Estimated Expiration
2044-03-18

AI Technical Summary

Technical Problem

The prior art has high recurrence rates and drug resistance problems in the treatment of bacterial vaginitis, and cannot effectively restore the normal microecological environment of the vagina.

Method used

Using Lactobacillus curl NCU-13 and its metabolites, vaginal probiotic sanitary napkins are used to activate and probiotics, inhibit the growth of pathogenic bacteria, and maintain vaginal health through vaginal flora transplantation.

Benefits of technology

Effectively prevent and treat bacterial vaginitis, restore vaginal microecological balance, and provide a safe, effective and easy-to-use treatment plan.

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Abstract

The present invention belongs to the field of microbial technology, and specifically relates to a strain of Lactobacillus crispatus NCU‑13 and its application. The name of the Lactobacillus crispatus NCU‑13 is Lactobacillus crispatus NCU‑13, which has been deposited in the General Microbiological Center of the China Microbiological Culture Collection Administration Committee on July 17, 2023, with a deposit number of CGMCC No.27918. The present invention evenly places the freeze-dried Lactobacillus crispatus powder in the absorption layer of the sanitary napkin, and when in use, utilizes the suitable environment of the human body and the moist environment formed during menstruation to activate and promote the activation and proliferation of probiotics attached to the sanitary napkin, so that it enters the vagina. The Lactobacillus crispatus and its beneficial metabolites can not only promote the health of the vaginal environment, but also improve the barrier function of the vaginal mucosa, and may help restore the balance of vaginal microecology through its anti-inflammatory and immunomodulatory effects, while optimizing female reproductive health.
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