Medicine for treating chronic prostatitis and prostatic hyperplasia

Abstract

The invention relates to the field of medicines, and discloses a medicine for treating chronic prostatitis and prostatic hypertrophy, which is prepared from the following raw materials in parts by weight: 14 to 18 parts of poria cocos, 12 to 17 parts of ligusticum wallichii, 12 to 15 parts of dried alum, 15 to 20 parts of bulbus fritillariae cirrhosae, 10 to 12 parts of radix peucedani, 6 to 10 parts of radix paeoniae alba, 5 to 9 parts of radix angelicae pubescentis, 5 to 10 parts of honey-fried licorice root, 7 to 14 parts of radix ophiopogonis, 15 to 20 parts of radix salviae miltiorrhizae, 15 to 20 parts of codonopsis pilosula, 12 to 18 parts of felwort, 15 to 20 parts of hippocampus powder, 10 to 25 parts of mixed compounding agent, 10 to 17 parts of prepared rehmannia root and 3 to 5 parts of corrigent, the mixed compound is prepared by the following method steps: step 1, taking herba epimedii, radix cyathulae and dianthus superbus, cleaning and drying the raw materials, and then crushing. According to the traditional Chinese medicine composition for treating chronic prostatitis and prostatic hypertrophy, a mixed compound is prepared, the medicinal materials are compatible to achieve a synergistic effect, the traditional Chinese medicine composition for treating chronic prostatitis and prostatic hypertrophy has a good effect on treating chronic prostatitis and prostatic hypertrophy, and the medicine is low in raw material cost and convenient to take and collect.

Description

Technical Field

[0001] The invention relates to the field of medicine, in particular to a medicine for treating chronic prostatitis and prostatic hypertrophy. Background Art

[0002] Chronic prostatitis refers to chronic inflammation of the prostate, which can be caused by a variety of factors, such as infection, local immune response, lifestyle habits, etc. The symptoms of chronic prostatitis include frequent urination, urgency, pain, residual urine, discomfort in the perineum or downward perineum, sexual dysfunction, etc. It is usually diagnosed through patient symptom description, physical examination, prostate massage fluid examination, urine analysis, etc. Chronic prostatitis can be treated with antibiotics to treat infection, Chinese medicine conditioning, physical therapy and other methods.

[0003] Prostatic hypertrophy, also known as benign prostatic hyperplasia, refers to the condition in which the prostate tissue continues to proliferate with age, leading to an increase in the size of the prostate. This is a physiological change that men generally experience. Symptoms of prostatic hypertrophy include frequent urination, urgency, a feeling of incomplete urination, frequent urination at night, difficulty urinating, dribbling urine, etc. It is usually diagnosed through symptom description, physical examination, prostate-specific antigen (PSA) test, rectal digital examination, etc. Prostatic hypertrophy can be treated with medication, surgery, minimally invasive interventional treatment, and other methods.

[0004] Prostate diseases will affect men's quality of life, so timely diagnosis and treatment are very important. Currently, the treatments for the above two types of prostate diseases mainly include α1 receptor blockers, 5α-reductase inhibitors, etc., but although the above drugs have rapid therapeutic effects, from the perspective of long-term therapeutic effects, they can only have a relieving effect, and it is difficult to treat them fundamentally. Therefore, the present invention aims to provide a drug for treating chronic prostatitis and prostatic hypertrophy to improve the shortcomings of current drugs in long-term efficacy. Summary of the invention

[0005] In view of the deficiencies in the prior art, the present invention provides a drug for treating chronic prostatitis and prostatic hypertrophy, which solves the problem that some drugs currently used to treat chronic prostatitis and prostatic hypertrophy have rapid effects but generally have some side effects and the sustained effects are limited.

[0006] To achieve the above objectives, the present invention is implemented through the following technical scheme: a medicine for treating chronic prostatitis and prostatic hypertrophy, comprising the following raw materials in parts by weight: 14-18 parts of Poria cocos, 12-17 parts of Chuanxiong, 12-15 parts of Alum, 15-20 parts of Fritillaria cirrhosa, 10-12 parts of Peucedanum chinense, 6-10 parts of White Peony Root, 5-9 parts of Angelica dahurica, 5-10 parts of Radix Glycyrrhizae Preparata, 7-14 parts of Ophiopogon japonicus, 15-20 parts of Salvia miltiorrhizae, 15-20 parts of Codonopsis pilosula, 12-18 parts of Gentiana scabra, 15-20 parts of Hippocampus powder, 10-25 parts of a mixed compound, 10-17 parts of Rehmannia glutinosa, and 3-5 parts of a flavoring agent.

[0007] Preferably, the flavoring agent is one of stevioside, glycyrrhizic acid and aromatics.

[0008] Preferably, the mixed compound is prepared by the following steps:

[0009] Step 1, taking epimedium, cyathula and superbus, washing and drying the above raw materials and then crushing them, adding sophora flavescens powder to the crushed materials and mixing them evenly, then adding 10 times the weight of all raw materials of water to the mixture, heating the water to boiling and keeping it for 15 to 30 minutes, after the end, cooling the water and filtering it to obtain a mixed filtrate;

[0010] Step 2: Take yam, peel and keep the meat, then use a homogenizer to beat the yam meat into a pulp, then add 5 times the total mass of water of the yam pulp, stir and mix, and then precipitate, and take the upper liquid to obtain yam glue;

[0011] Step three, add the mixed filtrate obtained in step one to the yam glue, mix and stir, add Atractylodes macrocephala, Dendrobium officinale and a certain amount of water during the stirring process, add talc and chitosan after preliminary mixing and stirring, and obtain the mixed compound product after secondary stirring.

[0012] Preferably, in step 1, the ratio of epimedium, cyathula, superbus and sophora flavescens powder is 1:2:1.5:3.

[0013] Preferably, in step three, the raw materials are respectively proportioned by weight as follows: 15-20 parts of yam glue, 20-30 parts of mixed filtrate, 5-7 parts of Atractylodes macrocephala, 4-6 parts of Dendrobium officinale, 1-3 parts of talc, 3-5 parts of chitosan, and 100-120 parts of water.

[0014] A method for preparing a drug for treating chronic prostatitis and prostatic hypertrophy, which is used to prepare the above-mentioned drug for treating chronic prostatitis and prostatic hypertrophy, comprises the following steps:

[0015] S1. First, select Poria cocos, Chuanxiong, Alum, Fritillaria cirrhosa, Peucedanum chinense and White Peony Root according to the weight ratio, wash and dry the above materials, and grind them to obtain a first-class medicinal powder raw material;

[0016] S2, putting the raw material of the drug powder prepared in step S1 into the first container and stirring with hot water to obtain a mixture 1, and then placing the first container in a low temperature environment and letting it stand for 2 to 3 days;

[0017] S3, selecting Angelica dahurica, Radix Glycyrrhizae Preparata and Radix Ophiopogonis for pulverization, and then adding them together with the mixed compound to the Chinese medicine extraction equipment for component extraction operation, after obtaining the medicinal material extract, pouring the medicinal material extract into the second container and adding hot water to stir to obtain the second mixture, and then placing the second container in a low temperature environment and letting it stand for 1 to 2 days;

[0018] S4, selecting Danshen and Codonopsis for pulverization to obtain a secondary medicinal powder raw material, then pouring the mixture one and the mixture two into a third container, heating and stirring for 15 to 25 minutes, adding the secondary medicinal powder raw material at the same time, stirring for 30 to 45 minutes, and filtering the material in the container to obtain a mixture three;

[0019] S5. Add gentian and Rehmannia root powder to the mixture prepared in step S4, mix and stir, and then use a granulator to granulate and dry to obtain a granular finished drug for treating chronic prostatitis and prostatic hypertrophy.

[0020] Preferably, in the step S2, the heating temperature of the first container is controlled at 60-85°C, and the static environment temperature of the first container is controlled at 5-10°C.

[0021] Preferably, in step S3, the crushed particle size of Angelica dahurica, Radix Glycyrrhizae Preparata and Radix Ophiopogonis is controlled at 2 mm or less, the heating temperature of the second container is controlled at 80-90°C, and the static environment temperature of the second container is controlled at 2-5°C.

[0022] Preferably, in the step S4, after mixture one and mixture two are added to the third container, 2% of the total mass of the materials is added to the mixture every 5 to 10 minutes, the stirring speed is controlled at 220 to 260 rpm / min, and the stirring time is controlled at 20 to 50 minutes.

[0023] Preferably, in the step S4, after the secondary medicinal powder raw material is added into the container, 2% of the total mass of the raw material is added into the Rosa laevigata powder every 2 to 8 minutes, the stirring speed is controlled at 220 to 240 rpm / min, and the stirring time is controlled at 20 to 30 minutes.

[0024] The present invention provides a medicine for treating chronic prostatitis and prostatic hypertrophy. It has the following beneficial effects:

[0025] 1. The present invention prepares a mixed compound, which is made by mixing a variety of Chinese herbal medicines with unique pharmacological effects. The mutual compatibility can play a synergistic role and help relieve the inflammation and symptoms caused by prostatitis. For the preparation of drugs for treating chronic prostatitis, it has low cost, convenient drug collection, and good therapeutic effect.

[0026] 2. The present invention adds seahorse powder to the traditional Chinese medicine compound, which helps to improve prostate problems caused by kidney yang deficiency, such as frequent urination and urgency, in the treatment of prostatitis and prostatic hypertrophy. At the same time, it contains protein and trace elements, which are helpful in relieving the pain and discomfort caused by prostatic hypertrophy, and also helps to relieve the symptoms of dryness and heat caused by prostatitis.

[0027] 3. The present invention has good pharmacological effects and potential therapeutic effects by purifying and refining the combined traditional Chinese medicinal ingredients in the form of a composite mixed preparation. At the same time, it has a comprehensive conditioning effect on chronic prostatitis and prostatic hypertrophy through multiple mechanisms of action, thereby achieving better therapeutic effects. At the same time, as a micro-pill dosage form, it is small in size, small in dosage, and easy to carry. The addition of chitosan makes it possible to prolong the naturalness of traditional Chinese medicine without adding any preservatives. BRIEF DESCRIPTION OF THE DRAWINGS

[0028] Figure 1 The figure is a schematic diagram of the overall process of preparing the drug of the present invention. DETAILED DESCRIPTION

[0029] The following will be combined with the contents of the specific embodiments of the present invention to clearly and completely describe the technical solution of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0030] Example:

[0031] Please refer to the attached Figure 1 The embodiment of the present invention provides a drug for treating chronic prostatitis and prostatic hypertrophy, comprising the following raw materials in parts by weight: 14-18 parts of Poria cocos, 12-17 parts of Chuanxiong, 12-15 parts of Alum, 15-20 parts of Fritillaria cirrhosa, 10-12 parts of Peucedanum chinense, 6-10 parts of White Peony Root, 5-9 parts of Angelica dahurica, 5-10 parts of Radix Glycyrrhizae Preparata, 7-14 parts of Radix Ophiopogonis, 15-20 parts of Salvia miltiorrhizae, 15-20 parts of Codonopsis pilosulae, 12-18 parts of Gentiana scabra, 15-20 parts of Seahorse Powder, 10-25 parts of a mixed compound, 10-17 parts of Rehmannia glutinosa, and 3-5 parts of a flavoring agent. Among the above-mentioned raw material components:

[0032] Poria cocos: It has diuretic, anti-edema and heat-clearing effects. It can help relieve symptoms such as frequent urination and urgency caused by prostatitis and help improve inflammation.

[0033] Chuanxiong: It has the effects of promoting blood circulation, removing blood stasis, relaxing menstruation and relieving pain. It is helpful in improving the pain and discomfort caused by prostatitis.

[0034] Alum: It has the effects of astringency, hemostasis, swelling and pain relief, and can be used to relieve inflammation and swelling caused by prostatitis.

[0035] Fritillaria cirrhosa: It has the effects of clearing heat and moistening the lungs, resolving phlegm and relieving cough. It is helpful for cough or airway discomfort caused by prostatitis.

[0036] Peucedanum chinense: It has the effects of removing phlegm and relieving cough, relieving exterior symptoms and dispersing cold, and can be used to improve the symptoms of phlegm and dampness caused by prostatitis.

[0037] White Peony Root: It has the effects of promoting blood circulation, removing blood stasis, regulating menstruation and relieving pain. It has a certain effect in relieving the pain and discomfort caused by prostatitis.

[0038] Angelica dahurica: It has the effects of dispelling wind and dampness, promoting blood circulation and relieving pain. It can be used to relieve rheumatic pain caused by prostatitis.

[0039] Roasted Licorice Root: It has the effect of relieving pain and harmonizing the properties of medicines. It can increase the efficacy of the medicine and help balance the formula.

[0040] Ophiopogon japonicus: It has the effects of nourishing yin and moistening the lungs, clearing away heat and quenching thirst, and can be used to relieve the heat symptoms caused by prostatitis.

[0041] Salvia miltiorrhiza: It has the effects of promoting blood circulation, removing blood stasis, reducing swelling and relieving pain. It is helpful in improving the pain and inflammation caused by prostatitis.

[0042] Codonopsis pilosula: It has the effects of replenishing qi and blood, benefiting the lungs and relieving cough, and can be used to improve the weak symptoms caused by prostatitis.

[0043] Gentian: The grass has the effects of clearing away heat and detoxifying, promoting bile secretion and removing stones, and has a certain effect on inflammation caused by prostatitis.

[0044] Hippocampus powder: In traditional Chinese medicine compound, seahorse powder is a traditional and precious tonic, usually used to nourish kidney yang, strengthen yang and kidney, strengthen tendons and bones, etc. In the treatment of prostatitis and prostatic hypertrophy, seahorse powder has the following effects and benefits. It helps to improve prostate problems caused by kidney yang deficiency, such as frequent urination and urgency. It is rich in protein and trace elements, which helps to strengthen tendons and bones, and is helpful in relieving pain and discomfort caused by prostatic hypertrophy. At the same time, seahorse has the effect of benefiting essence and consolidating essence, which can improve sexual dysfunction caused by prostatitis and prostatic hypertrophy, and also help to relieve the symptoms of dryness and heat caused by prostatitis.

[0045] Rehmannia root: Rehmannia root has the effects of nourishing yin and kidney, benefiting the heart and calming the mind. It can be used to improve the symptoms of kidney deficiency caused by prostate hypertrophy.

[0046] The flavoring agent is one of stevioside, glycyrrhizic acid and aromatics.

[0047] Specifically, in the present invention, the mixed compound is a Chinese medicine compound prepared by mixing multiple drugs in a certain proportion, which can comprehensively exert the effects of various drugs and enhance the therapeutic effect. The mixed compound is prepared by the following method steps:

[0048] Step 1, taking epimedium, cyathula and superbus, washing and drying the above raw materials and then crushing them, adding sophora flavescens powder to the crushed materials and mixing them evenly, then adding 10 times the weight of water of all raw materials to the mixture, heating the water to boiling and keeping it for 15 to 30 minutes, cooling and filtering the water after the end to obtain a mixed filtrate, in this step, the ratio of epimedium, cyathula, superbus and sophora flavescens powder is 1:2:1.5:3;

[0049] Step 2: Take yam, peel and keep the meat, then use a homogenizer to beat the yam meat into a pulp, then add 5 times the total mass of water of the yam pulp, stir and mix, and then precipitate, and take the upper liquid to obtain yam glue;

[0050] Step three, add the mixed filtrate obtained in step one to the yam glue, mix and stir, add Atractylodes macrocephala, Dendrobium officinale and a certain amount of water during the stirring process, add talc and chitosan after preliminary mixing and stirring, and obtain the mixed compound product after secondary stirring. In this step, the raw materials are respectively proportioned by weight: 15-20 parts of yam glue, 20-30 parts of mixed filtrate, 5-7 parts of Atractylodes macrocephala, 4-6 parts of Dendrobium officinale, 1-3 parts of talc, 3-5 parts of chitosan, and 100-120 parts of water.

[0051] In the above steps, the effects and benefits of the drug ingredients used in the treatment of prostatitis and prostatic hypertrophy include:

[0052] Epimedium: It has the effect of warming the kidney and strengthening yang, strengthening tendons and bones. It is often used to treat symptoms such as impotence and weak ejaculation caused by prostatitis and prostatic hypertrophy.

[0053] Sichuan Achyranthes bidentata: It has the effects of promoting blood circulation, removing blood stasis, strengthening tendons and bones, and can be used to improve the pain and discomfort caused by prostatitis.

[0054] Dianthus superbus: It has the effects of clearing away heat and detoxifying, diuresis and reducing swelling, and is helpful in relieving urinary tract symptoms caused by prostatitis.

[0055] Sophora flavescens: It has the effects of clearing away heat and detoxifying, killing bacteria and reducing inflammation, and can be used to treat inflammation caused by prostatitis.

[0056] Yam: It has the effects of invigorating qi and strengthening the spleen, nourishing the kidneys and consolidating essence, and it has a certain effect on improving spleen and kidney deficiency caused by prostatitis.

[0057] Atractylodes: It has the effects of strengthening the spleen and stomach, replenishing qi and blood, and can help relieve the symptoms of spleen and stomach weakness caused by prostatitis.

[0058] Dendrobium: It has the effects of nourishing yin and clearing heat, moistening the lungs and relieving cough, and can be used to improve the heat symptoms caused by prostatitis.

[0059] Talc: It has the effects of clearing away heat and dampness, stopping bleeding and reducing swelling, and can help relieve inflammation and swelling caused by prostatitis.

[0060] Chitosan: It has antibacterial and anti-inflammatory effects, promotes wound healing, and helps treat infections and inflammations caused by prostatitis.

[0061] Furthermore, the present invention also provides a method for preparing a drug for treating chronic prostatitis and prostatic hypertrophy, which is used to prepare the above-mentioned drug for treating chronic prostatitis and prostatic hypertrophy, comprising the following steps:

[0062] S1. First, select Poria cocos, Chuanxiong, Alum, Fritillaria cirrhosa, Peucedanum chinense and White Peony Root according to the weight ratio, wash and dry the above materials, and grind them to obtain a first-class medicinal powder raw material;

[0063] S2, putting the raw material of the powder prepared in step S1 into a first container and stirring with heated water to obtain a mixture 1, then placing the first container in a low temperature environment and letting it stand for 2 to 3 days. In this step, the heating temperature of the first container is controlled at 60 to 85° C., and the standing environment temperature of the first container is controlled at 5 to 10° C.;

[0064] S3, selecting angelica dahurica, licorice root and ophiopogon japonicus for pulverization, and then adding them together with the mixed compound to the traditional Chinese medicine extraction equipment for component extraction operation, after obtaining the medicinal material extract, pouring the medicinal material extract into the second container and adding hot water to stir to obtain the second mixture, and then placing the second container in a low temperature environment for 1 to 2 days. In this step, the pulverized particle size of angelica dahurica, licorice root and ophiopogon japonicus is controlled at 2 mm or less, the heating temperature of the second container is controlled at 80 to 90° C., and the static environment temperature of the second container is controlled at 2 to 5° C.;

[0065] S4, select Danshen and Codonopsis for crushing to obtain a secondary medicinal powder raw material, then pour the mixture one and the mixture two into a third container, heat and stir for 15 to 25 minutes, add the secondary medicinal powder raw material at the same time, stir for 30 to 45 minutes, filter the material in the container to obtain a mixture three, in this step, after the mixture one and the mixture two are added to the third container, add 2% of the total mass of the material Zedoaria powder every 5 to 10 minutes, control the stirring speed at 220 to 260 rpm / min, and control the stirring time at 20 to 50 minutes. At the same time, after the secondary medicinal powder raw material is added to the container, add 2% of the total mass of the material Rosa laevigata powder every 2 to 8 minutes, control the stirring speed at 220 to 240 rpm / min, and control the stirring time at 20 to 30 minutes;

[0066] S5. Add gentian and Rehmannia root powder to the mixture prepared in step S4, mix and stir, and then use a granulator to granulate and dry to obtain a granular finished drug for treating chronic prostatitis and prostatic hypertrophy.

[0067] The present invention will be further introduced and described below in conjunction with specific embodiments:

[0068] Embodiment 1:

[0069] The present embodiment provides a medicine for treating chronic prostatitis and prostatic hypertrophy, comprising the following raw materials in parts by weight: 14 parts of Poria cocos, 12 parts of Chuanxiong, 12 parts of Alum, 15 parts of Fritillaria cirrhosa, 10 parts of Peucedanum chinense, 6 parts of White Peony Root, 5 parts of Angelica dahurica, 5 parts of Radix Glycyrrhizae Preparata, 7 parts of Ophiopogon japonicus, 15 parts of Salvia miltiorrhizae, 15 parts of Codonopsis pilosula, 12 parts of Gentiana scabra, 20 parts of hippocampus powder, 25 parts of a mixed compound, 10 parts of Rehmannia glutinosa, and parts of a flavoring agent.

[0070] Among the above raw materials, the flavoring agent is stevioside. Meanwhile, the mixed compound is prepared by the following steps:

[0071] Step 1, taking epimedium, cyathula and superbus, washing and drying the above raw materials and then crushing them, adding sophora flavescens powder to the crushed materials and mixing them evenly, then adding 10 times the weight of water of all raw materials to the mixture, heating the water to boiling and keeping it for 15 minutes, after which the water is cooled and filtered to obtain a mixed filtrate, wherein the ratio of epimedium, cyathula, superbus and sophora flavescens powder is 1:2:1.5:3;

[0072] Step 2: Take yam, peel and keep the meat, then use a homogenizer to beat the yam meat into a pulp, then add 5 times the total mass of water of the yam pulp, stir and mix, and then precipitate, and take the upper liquid to obtain yam glue;

[0073] Step three, add the mixed filtrate obtained in step one to the yam glue, mix and stir, add Atractylodes macrocephala, Dendrobium officinale and a certain amount of water during the stirring process, add talc and chitosan after preliminary mixing and stirring, and obtain the mixed compound product after secondary stirring. In this step, the raw materials are respectively proportioned by weight: 15-20 parts of yam glue, 20-30 parts of mixed filtrate, 5-7 parts of Atractylodes macrocephala, 4-6 parts of Dendrobium officinale, 1-3 parts of talc, 3-5 parts of chitosan, and 100-120 parts of water.

[0074] Furthermore, this embodiment also provides a method for preparing a drug for treating chronic prostatitis and prostatic hypertrophy, which is used to prepare the drug for treating chronic prostatitis and prostatic hypertrophy mentioned in this embodiment, comprising the following steps:

[0075] S1. First, select Poria cocos, Chuanxiong, Alum, Fritillaria cirrhosa, Peucedanum chinense and White Peony Root according to the weight ratio, wash and dry the above materials, and grind them to obtain a first-class medicinal powder raw material;

[0076] S2, putting the raw material of the medicinal powder prepared in step S1 into a first container, adding hot water and stirring to obtain a mixture 1, and then placing the first container in a low temperature environment and letting it stand for 3 days. In this step, the heating temperature of the first container is controlled at 85° C., and the standing environment temperature of the first container is controlled at 10° C.;

[0077] S3, selecting angelica dahurica, licorice root and ophiopogon japonicus for pulverization, and then adding them together with the mixed compound to the traditional Chinese medicine extraction equipment for component extraction operation, after obtaining the medicinal material extract, pouring the medicinal material extract into a second container and adding hot water to stir to obtain a second mixture, and then placing the second container in a low temperature environment for 2 days. In this step, the pulverized particle size of angelica dahurica, licorice root and ophiopogon japonicus is controlled at 2 mm or less, the heating temperature of the second container is controlled at 90° C., and the static environment temperature of the second container is controlled at 5° C.;

[0078] S4, select Danshen and Codonopsis for crushing to obtain a secondary medicinal powder raw material, then pour the mixture one and the mixture two into a third container, heat and stir for 25 minutes, add the secondary medicinal powder raw material at the same time, stir for 45 minutes, and filter the material in the container to obtain a mixture three. In this step, in step S4, after the mixture one and the mixture two are added to the third container, 2% of the total mass of the material is added to the Zedoaria powder every 5 minutes, the stirring speed is controlled at 220rpm / min, and the stirring time is controlled at 20 to 50 minutes. At the same time, in step S4, after the secondary medicinal powder raw material is added to the container, 2% of the total mass of the material is added to the Rosa laevigata powder every 8 minutes, the stirring speed is controlled at 220rpm / min, and the stirring time is controlled at 24 minutes;

[0079] S5. Add gentian and Rehmannia root powder to the mixture prepared in step S4, mix and stir, and then use a granulator to granulate and dry to obtain a granular finished drug for treating chronic prostatitis and prostatic hypertrophy.

[0080] Embodiment 2:

[0081] The present embodiment provides a medicine for treating chronic prostatitis and prostatic hypertrophy, comprising the following raw materials in parts by weight: 14 parts of Poria cocos, 12 parts of Chuanxiong, 12 parts of Alum, 15 parts of Fritillaria cirrhosa, 10 parts of Peucedanum chinense, 6 parts of White Peony Root, 5 parts of Angelica dahurica, 5 parts of Radix Glycyrrhizae Preparata, 7 parts of Radix Ophiopogonis, 15 parts of Salvia miltiorrhizae, 15 parts of Codonopsis pilosulae, 12 parts of Gentiana scabra, 18 parts of Seahorse Powder, 20 parts of mixed compound, 10 parts of Rehmannia glutinosa, and 1 part of flavoring agent;

[0082] In this embodiment, the preparation formula and process of the mixed compound and the entire drug are consistent with those in Example 1, except that the usage ratios of some raw materials are different.

[0083] Embodiment 3:

[0084] The present embodiment provides a medicine for treating chronic prostatitis and prostatic hypertrophy, comprising the following raw materials in parts by weight: 14 parts of Poria cocos, 12 parts of Chuanxiong, 12 parts of Alum, 15 parts of Fritillaria cirrhosa, 10 parts of Peucedanum chinense, 6 parts of White Peony Root, 5 parts of Angelica dahurica, 5 parts of Radix Glycyrrhizae Preparata, 7 parts of Radix Ophiopogonis, 15 parts of Salvia miltiorrhizae, 15 parts of Codonopsis pilosulae, 12 parts of Gentiana scabra, 16 parts of Seahorse Powder, 15 parts of a mixed compound, 10 parts of Rehmannia glutinosa, and 1 part of a flavoring agent;

[0085] In this embodiment, the preparation formula and process of the mixed compound and the entire drug are consistent with those in the embodiment, the difference is that the usage proportions of some raw materials are different.

[0086] Embodiment 4:

[0087] The present embodiment provides a medicine for treating chronic prostatitis and prostatic hypertrophy, comprising the following raw materials in parts by weight: 14 parts of Poria cocos, 12 parts of Chuanxiong, 12 parts of Alum, 15 parts of Fritillaria cirrhosa, 10 parts of Peucedanum chinense, 6 parts of White Peony Root, 5 parts of Angelica dahurica, 5 parts of Radix Glycyrrhizae Preparata, 7 parts of Radix Ophiopogonis, 15 parts of Salvia miltiorrhizae, 15 parts of Codonopsis pilosulae, 12 parts of Gentiana scabra, 15 parts of Seahorse Powder, 13 parts of mixed compound, 10 parts of Rehmannia glutinosa, and parts of flavoring agent;

[0088] In this embodiment, the preparation formula and process of the mixed compound and the entire drug are consistent with those in the embodiment, the difference is that the usage proportions of some raw materials are different.

[0089] Embodiment 5:

[0090] The present embodiment provides a medicine for treating chronic prostatitis and prostatic hypertrophy, comprising the following raw materials in parts by weight: 14 parts of Poria cocos, 12 parts of Chuanxiong, 12 parts of Alum, 15 parts of Fritillaria cirrhosa, 10 parts of Peucedanum chinense, 6 parts of White Peony Root, 5 parts of Angelica dahurica, 5 parts of Radix Glycyrrhizae Preparata, 7 parts of Radix Ophiopogonis, 15 parts of Salvia miltiorrhizae, 15 parts of Codonopsis pilosulae, 12 parts of Gentiana scabra, 15 parts of Seahorse Powder, 10 parts of a mixed compound, 10 parts of Rehmannia glutinosa, and 1 part of a flavoring agent;

[0091] In this embodiment, the preparation formula and process of the mixed compound and the entire drug are consistent with those in the embodiment, the difference is that the usage proportions of some raw materials are different.

[0092] Specific drug experiments:

[0093] In this embodiment, the present invention is further described mainly through specific experimental operations. In the present invention, the experimental conditions of the drug for treating chronic prostatitis and prostatic hypertrophy are as follows:

[0094] Experimental environment: Experimental group and control group:

[0095] A total of 120 subjects were randomly divided into two groups: an experimental group and a control group.

[0096] Experimental group: received prostate drug treatment, consisting of five drugs.

[0097] Control group: received conventional drug treatment, including:

[0098] Alpha-blockers: Help relax the muscles of the prostate and bladder neck, relieve symptoms such as frequent urination and urgency, and use terazosin and felodipine and ginkgo leaf extract;

[0099] 5α-reductase inhibitors: including tazonafil, bacterial infection drugs, including fluoroquinolones such as norfloxacin and levofloxacin, cephalosporins such as cefaclor and cefradine

[0100] Nonsteroidal anti-inflammatory drugs: used to relieve pain and inflammation caused by prostatitis, including: ibuprofen, aspirin;

[0101] Bladder smooth muscle relaxants: These can help relieve symptoms such as frequent urination and urgency, including oxapram and diltiazem

[0102] Experiment duration:

[0103] 8 weeks.

[0104] Evaluation Metrics:

[0105] Including symptom improvement of prostatitis and prostatic hypertrophy, quality of life assessment, etc.

[0106] Experimental steps:

[0107] 1. Random grouping:

[0108] The participants were divided into five drug experimental groups and a control group by random grouping method, and the five drug experimental groups corresponded to the five drugs prepared in Examples 1-5 of the present invention, respectively.

[0109] 2. Drug treatment:

[0110] The experimental group received prostate drug treatment according to the drug dosage and frequency.

[0111] The control group received traditional drug treatment.

[0112] 3. Treatment evaluation:

[0113] Conduct an intermediate evaluation at a certain point in the experiment to compare the efficacy of the two groups and record it in a table.

[0114] The data obtained after 8 weeks of the above experiment are shown in Table 1 below:

[0115] Table 1, comparison table of treatment effects of experimental groups 1-5 and control group:

[0116] Serial number Number of people cure Significant effect invalid Treatment effectiveness Original patient 120 0 0 0 0％ Experimental Group 1 20 15 4 1 95％ Experimental Group 2 20 15 3 2 90％ Experimental Group 3 20 13 6 1 95％ Experimental Group 4 20 14 3 3 85％ Experimental Group 5 20 13 4 2 85％ Control group 20 8 7 5 75％

[0117] According to the experiment and with reference to the data obtained in Table 1, it can be concluded that the drug for treating chronic prostatitis and prostatic hypertrophy provided in the embodiment of the present invention has good pharmacological effects and therapeutic effects on chronic prostatitis and prostatic hypertrophy. Each Chinese herbal medicine has its unique pharmacological effect, and the mutual compatibility has a synergistic effect that helps to relieve the inflammation and symptoms caused by prostatitis. At the same time, it has a comprehensive conditioning effect on chronic prostatitis and prostatic hypertrophy through multiple mechanisms of action, thereby achieving better therapeutic effects, and has a good and long-lasting positive effect on the treatment of chronic prostatitis and prostatic hypertrophy.

[0118] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A drug for treating chronic prostatitis and prostatic hypertrophy, characterized in that: The invention comprises the following raw materials in parts by weight: 14-18 parts of Poria cocos, 12-17 parts of Chuanxiong, 12-15 parts of Alum, 15-20 parts of Fritillaria cirrhosa, 10-12 parts of Peucedanum chinense, 6-10 parts of White Peony Root, 5-9 parts of Angelica dahurica, 5-10 parts of Radix Glycyrrhizae Preparata, 7-14 parts of Ophiopogon japonicus, 15-20 parts of Salvia miltiorrhizae, 15-20 parts of Codonopsis pilosula, 12-18 parts of Gentiana scabra, 15-20 parts of Seahorse Powder, 10-25 parts of mixed compound, 10-17 parts of Rehmannia glutinosa, and 3-5 parts of flavor corrective.

2. A drug for treating chronic prostatitis and prostatic hypertrophy according to claim 1, characterized in that: The flavoring agent is one of stevioside, glycyrrhizic acid and aromatics.

3. A drug for treating chronic prostatitis and prostatic hypertrophy according to claim 1, characterized in that: The mixed compound is prepared by the following steps: Step 1, taking epimedium, cyathula and superbus, washing and drying the above raw materials and then crushing them, adding sophora flavescens powder to the crushed materials and mixing them evenly, then adding 10 times the weight of all raw materials of water to the mixture, heating the water to boiling and keeping it for 15 to 30 minutes, after the end, cooling the water and filtering it to obtain a mixed filtrate; Step 2: Take yam, peel and keep the meat, then use a homogenizer to beat the yam meat into a pulp, then add 5 times the total mass of water of the yam pulp, stir and mix, and then precipitate, and take the upper liquid to obtain yam glue; Step three, add the mixed filtrate obtained in step one to the yam glue, mix and stir, add Atractylodes macrocephala, Dendrobium officinale and a certain amount of water during the stirring process, add talc and chitosan after preliminary mixing and stirring, and obtain the mixed compound product after secondary stirring.

4. A drug for treating chronic prostatitis and prostatic hypertrophy according to claim 3, characterized in that: In the step 1, the ratio of epimedium, cyathula, superbus and sophora flavescens powder is 1:2:1.5:

3.

5. The drug for treating chronic prostatitis and prostatic hypertrophy according to claim 3, characterized in that: In the step three, the raw materials are respectively mixed in proportions by weight: 15-20 parts of yam glue, 20-30 parts of mixed filtrate, 5-7 parts of Atractylodes macrocephala, 4-6 parts of Dendrobium officinale, 1-3 parts of talc, 3-5 parts of chitosan, and 100-120 parts of water.

6. A method for preparing a drug for treating chronic prostatitis and prostatic hypertrophy, characterized in that: A drug for treating chronic prostatitis and prostatic hypertrophy as claimed in any one of claims 1 to 5, comprising the following steps: S1. First, select Poria cocos, Chuanxiong, Alum, Fritillaria cirrhosa, Peucedanum chinense and White Peony Root according to the weight ratio, wash and dry the above materials, and grind them to obtain a first-class medicinal powder raw material; S2, putting the raw material of the powder prepared in step S1 into the first container and stirring with hot water to obtain a mixture 1, and then placing the first container in a low temperature environment and letting it stand for 2 to 3 days; S3, selecting Angelica dahurica, Radix Glycyrrhizae Preparata and Radix Ophiopogonis for pulverization, and then adding them together with the mixed compound to the Chinese medicine extraction equipment for component extraction operation, after obtaining the medicinal material extract, pouring the medicinal material extract into the second container and adding hot water to stir to obtain the second mixture, and then placing the second container in a low temperature environment and letting it stand for 1 to 2 days; S4, selecting Danshen and Codonopsis for pulverization to obtain a secondary medicinal powder raw material, then pouring the mixture one and the mixture two into a third container, heating and stirring for 15 to 25 minutes, adding the secondary medicinal powder raw material at the same time, stirring for 30 to 45 minutes, and filtering the material in the container to obtain a mixture three; S5. Add gentian and Rehmannia root powder to the mixture prepared in step S4, mix and stir, and then use a granulator to granulate and dry to obtain a granular finished drug for treating chronic prostatitis and prostatic hypertrophy.

7. The method for preparing a drug for treating chronic prostatitis and prostatic hypertrophy according to claim 6, characterized in that: In the step S2, the heating temperature of the first container is controlled at 60-85°C, and the static environment temperature of the first container is controlled at 5-10°C.

8. The method for preparing a drug for treating chronic prostatitis and prostatic hypertrophy according to claim 6, characterized in that: In the step S3, the particle size of the pulverized Angelica dahurica, Radix Glycyrrhizae Preparata and Radix Ophiopogonis is controlled at 2 mm or less, the heating temperature of the second container is controlled at 80-90° C., and the static environment temperature of the second container is controlled at 2-5° C.

9. The method for preparing a drug for treating chronic prostatitis and prostatic hypertrophy according to claim 6, characterized in that: In the step S4, after mixture 1 and mixture 2 are added into the third container, 2% of the total mass of the materials is added into the powder of Zedoaria every 5 to 10 minutes, the stirring speed is controlled at 220 to 260 rpm / min, and the stirring time is controlled at 20 to 50 minutes.

10. The method for preparing a drug for treating chronic prostatitis and prostatic hypertrophy according to claim 6, characterized in that: In the step S4, after the secondary medicinal powder raw material is added into the container, 2% of the total mass of the material is added into the Rosa laevigata powder every 2 to 8 minutes, the stirring speed is controlled at 220 to 240 rpm / min, and the stirring time is controlled at 20 to 30 minutes.

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