Preparation method and application of skin care product rich in ergothioneine and nicotinamide

Abstract

The invention provides a preparation method and application of a skin care product rich in ergothioneine and nicotinamide, and belongs to the technical field of skin care products.According to the scheme, an ergothioneine solution is treated with a stabilizer, the pH value of a nicotinamide solution is adjusted, tea polyphenol is added, stability is improved, specific temperature, humidity and containers are specified in the storage link, and deterioration is prevented; ergothioneine and nicotinamide synergistically exert multiple effects to meet various requirements of consumers, the preparation process is scientific and reasonable, segmented stirring and temperature control are performed, specific components are added and treated, the product quality is ensured, finally, a high-temperature instantaneous sterilization method is adopted, the product safety and stability are ensured, the microbial index standard is met, and in a word, the preparation method is suitable for industrial production. The invention has obvious advantages and wide market prospect.

Description

Technical Field

[0001] The invention belongs to the technical field of skin care products, and particularly relates to a preparation method and application of a skin care product rich in ergothioneine and niacinamide. Background Art

[0002] As people's living standards continue to improve and their pursuit of beauty becomes stronger, the skin care product market continues to prosper. Consumers have higher and higher requirements for the efficacy and safety of skin care products. They not only hope that the products can effectively improve the skin condition, but also require the product ingredients to be natural, mild and non-irritating.

[0003] At present, there are many kinds of skin care products on the market, but the comprehensive effects in terms of anti-oxidation, whitening, moisturizing, reducing wrinkles, soothing sensitivity and repairing damaged skin are often unsatisfactory. As a natural antioxidant, ergothioneine has strong antioxidant capacity, can effectively remove free radicals and protect skin cells from oxidative damage. Niacinamide performs well in whitening and moisturizing, can inhibit melanin production and increase the moisture content of the skin. However, it has always been a technical problem in the industry to effectively combine ergothioneine and niacinamide in a skin care product and ensure their stability and efficacy. When dealing with ergothioneine and niacinamide, traditional skin care product preparation methods often have problems such as poor stability, poor solubility, and difficulty in fully exerting their efficacy. For example, ergothioneine is easily degraded in the solution, affecting its antioxidant effect; the stability of niacinamide is also affected by factors such as pH value, and it is easy to discolor or lose activity. In addition, the traditional preparation process may not be able to fully mix the ingredients during stirring and homogenization, affecting the quality and use of the product.

[0004] In order to meet consumers' demand for high-quality skin care products, developing a preparation method for a skin care product rich in ergothioneine and niacinamide and improving the stability and efficacy of the product have important practical significance and market value. Summary of the invention

[0005] The object of the present invention is to provide a preparation method and application of a skin care product rich in ergothioneine and niacinamide, aiming to solve the problems in the prior art.

[0006] To achieve the above object, the present invention provides the following technical solutions:

[0007] A method for preparing a skin care product rich in ergothioneine and niacinamide comprises the following steps:

[0008] Step 1: preparing thioneine solution and nicotinamide solution respectively, treating the thioneine solution with a stabilizer having a mass fraction of 0.5%-1.5% to improve its stability and solubility; adjusting the pH value of the nicotinamide solution to 5-7;

[0009] Step 2: mixing the pretreated ergothioneine solution and the nicotinamide solution according to a specific ratio of 1:2-1:6 in which the mass ratio of ergothioneine to nicotinamide is 1:2 to 1:6 to form a mixed solution;

[0010] Step 3: Add skin care base ingredients to the mixed solution, wherein the moisturizer is 2%-10% by mass of glycerin, 0.1%-0.8% by mass of sodium hyaluronate and other suitable moisturizing ingredients, the emollient is 4%-12% by mass of natural oil or synthetic oil, and the emulsifier is 1%-4% by mass of non-ionic emulsifier or other suitable emulsifier, and stir at a specific stirring speed of 400-1000 rpm for 20-90 minutes, and then homogenize at a homogenization pressure of 8-25 MPa for 8-25 minutes to obtain a skin care product rich in ergothioneine and niacinamide. The skin care product can be used in a variety of skin condition improvement scenarios, including but not limited to anti-oxidation, whitening, moisturizing, wrinkle reduction, soothing sensitivity, repairing damaged skin, etc.

[0011] As a preferred scheme of the present invention, the preparation of the thioneine solution adopts the process of fermentation extraction from natural fungi, through specific fermentation condition control and extraction step, the extraction rate is not less than 55%, in the extraction process, the natural fungi is first inoculated in a specific culture medium, fermented for a certain time under the conditions of temperature of 25 DEG C-30 DEG C and pH value of 6-7, then extracted with a specific solvent, and after extraction, the thioneine solution is obtained through filtering, concentration and other steps.

[0012] As a preferred solution of the present invention, during the preparation of the nicotinamide solution, 0.2%-0.4% by mass of natural antioxidant tea polyphenols is added to further improve the stability of nicotinamide. During the preparation, nicotinamide is dissolved in an appropriate amount of deionized water, and after the tea polyphenols are added, the solution is stirred at a specific temperature until it is completely dissolved.

[0013] As a preferred solution of the present invention, the stirring process adopts a segmented stirring method, first stirring at a speed of 300 rpm for 15 minutes to preliminarily mix the ingredients, and then increasing the speed to 600 rpm for 45 minutes to ensure that the ingredients are fully mixed. During the stirring process, the temperature is controlled at 30°C-40°C to avoid excessive temperature affecting product quality.

[0014] As a preferred solution of the present invention, after the homogenization treatment, the skin care product is sterilized by high-temperature instantaneous sterilization at a temperature of 120°C-130°C for 3-5 seconds to ensure the safety and stability of the product. The microbial indicators of the product after sterilization meet the relevant standards, such as the total colony count not exceeding 100 CFU / g, and the total number of molds and yeasts not exceeding 50 CFU / g.

[0015] As a preferred solution of the present invention, the skin care product should be placed in an environment with a temperature of 10°C-20°C and a relative humidity not exceeding 55% during storage, and the storage container should be made of specific materials and sealed to prevent the product from being affected by external factors and deteriorating.

[0016] As a preferred solution of the present invention, the skin care product can be used for skin care of other parts of the body such as the neck and hands in addition to daily facial care. When using it, the method of use and the amount of use can be adjusted according to the skin characteristics of different parts to achieve improvement of the skin of the whole body.

[0017] Compared with the prior art, the present invention has the following beneficial effects:

[0018] By treating the ergothioneine solution with a stabilizer, its stability and solubility are improved, and ergothioneine is effectively prevented from degrading in the solution, ensuring that the powerful antioxidant effect can be continuously exerted. At the same time, the pH value of the niacinamide solution is adjusted to 5-7, and the natural antioxidant tea polyphenols are added to further improve the stability of niacinamide and avoid its discoloration or loss of activity. In the storage process, specific temperature and relative humidity environments are specified, and storage containers with specific materials and sealing methods are used to fully guarantee the stability of the product and prevent deterioration. Secondly, it performs well in terms of efficacy. Ergothioneine, as a natural antioxidant, can effectively remove free radicals and protect skin cells from oxidative damage. Niacinamide has obvious advantages in whitening and moisturizing, inhibiting melanin production and increasing skin moisture content. The two are stored in a specific ratio The ingredients are mixed and work synergistically to comprehensively exert multiple functions such as anti-oxidation, whitening, moisturizing, reducing wrinkles, soothing sensitivity and repairing damaged skin, etc., which meet the various needs of consumers for skin care products. Moreover, the preparation process is scientific and reasonable. The stirring process adopts a segmented stirring method. The ingredients are first mixed at a speed of 300 rpm, and then increased to 600 rpm to fully stir. At the same time, the temperature is controlled within an appropriate range to avoid excessive temperature affecting product quality. Moisturizers, emollients and emulsifiers are added to the mixed solution in specific proportions, and the ingredients are fully mixed through specific stirring speeds and homogenizing pressure treatments to ensure product quality and use effect. Finally, the product is sterilized by high-temperature instantaneous sterilization to ensure product safety and stability, and meet relevant microbial indicator standards. DETAILED DESCRIPTION

[0019] The technical solutions in the embodiments of the present invention will be described clearly and completely below in combination with the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0020] Example 1

[0021] The present invention provides the following technical solutions:

[0022] A method for preparing a skin care product rich in ergothioneine and niacinamide comprises the following steps:

[0023] Step 1: preparing thioneine solution and nicotinamide solution respectively, treating the thioneine solution with a stabilizer having a mass fraction of 0.5%-1.5% to improve its stability and solubility; adjusting the pH value of the nicotinamide solution to 5-7;

[0024] Step 2: mixing the pretreated ergothioneine solution and the nicotinamide solution according to a specific ratio of 1:2-1:6 in which the mass ratio of ergothioneine to nicotinamide is 1:2 to 1:6 to form a mixed solution;

[0025] Step 3: Add skin care base ingredients to the mixed solution, wherein the moisturizer is 2%-10% by mass of glycerin, 0.1%-0.8% by mass of sodium hyaluronate and other suitable moisturizing ingredients, the emollient is 4%-12% by mass of natural oil or synthetic oil, and the emulsifier is 1%-4% by mass of non-ionic emulsifier or other suitable emulsifier, and stir at a specific stirring speed of 400-1000 rpm for 20-90 minutes, and then homogenize at a homogenization pressure of 8-25 MPa for 8-25 minutes to obtain a skin care product rich in ergothioneine and niacinamide. The skin care product can be used in a variety of skin condition improvement scenarios, including but not limited to anti-oxidation, whitening, moisturizing, wrinkle reduction, soothing sensitivity, repairing damaged skin, etc.

[0026] In a specific embodiment of the present invention, in step one, thioneine solution is treated with a stabilizer having a mass fraction of 0.5%-1.5%, which greatly improves the stability and solubility of thioneine. This means that during the use of the product, thioneine can continue to exert a powerful antioxidant effect, effectively remove free radicals, and protect skin cells from oxidative damage. At the same time, the nicotinamide solution is adjusted to a pH value of 5-7 so that it is in a suitable pH range, which helps to maintain the stability of nicotinamide and avoid discoloration or loss of activity. In step two, thioneine and nicotinamide solution are mixed according to a specific ratio, and the synergistic effect of the two can be fully exerted, and the efficacy of skin care products is comprehensively improved. In step three, a specific ratio of moisturizer, emollient and emulsifier is added, and by a specific stirring speed and homogenizing pressure treatment, each component is fully mixed and uniformly mixed to ensure product quality and use effect. These measures work together so that skin care products can meet the needs of consumers in many aspects such as anti-oxidation, whitening, moisturizing, reducing wrinkles, soothing sensitivity and repairing damaged skin.

[0027] Specifically, the preparation of thioneine solution adopts the process of fermentation extraction from natural fungi, and the extraction rate is not less than 55% through specific fermentation condition control and extraction steps. In the extraction process, the natural fungi are first inoculated in a specific culture medium, and fermented for a certain time under the conditions of a temperature of 25°C-30°C and a pH value of 6-7, and then extracted with a specific solvent. After extraction, the thioneine solution is obtained through filtering, concentration and other steps.

[0028] In the present embodiment: by specific fermentation condition control, that is, temperature is 25 ℃-30 ℃, pH value is 6-7 condition fermentation certain time, can ensure that natural fungus efficiently synthesizes ergothioneine.This natural source extraction method not only improves the safety of product, meets the pursuit of natural ingredients by consumers, but also can ensure that higher extraction rate is not less than 55%.During extraction, natural fungus is first inoculated in specific culture medium, provides suitable growth environment for it, promotes the accumulation of ergothioneine.After extraction, the ergothioneine solution obtained by steps such as filtering and concentrating is purer, and stability is better.The application of this process makes the ergothioneine in skin care products have higher quality and efficacy, can bring better skin care experience to consumers.

[0029] Specifically, during the preparation of the nicotinamide solution, 0.2%-0.4% by mass of natural antioxidant tea polyphenols is added to further improve the stability of nicotinamide. During the preparation, nicotinamide is dissolved in an appropriate amount of deionized water, and after adding tea polyphenols, it is stirred at a specific temperature until it is completely dissolved.

[0030] In this embodiment: during the preparation of the niacinamide solution, a natural antioxidant tea polyphenol with a mass fraction of 0.2%-0.4% is added to further improve the stability of niacinamide. Tea polyphenols, as a natural antioxidant, can work synergistically with niacinamide to jointly resist oxidative stress. This not only helps to maintain the activity of niacinamide and prevent it from changing color or losing its efficacy, but also enhances the overall antioxidant capacity of skin care products. Nicotinamide is dissolved in an appropriate amount of deionized water, and after adding tea polyphenols, it is stirred at a specific temperature until completely dissolved, ensuring uniform mixing of the ingredients. This preparation method enables niacinamide to better play its whitening, moisturizing and other roles in skin care products, providing consumers with more effective skin care effects. At the same time, the addition of natural antioxidant tea polyphenols also meets consumers' demand for natural and mild skin care products.

[0031] Specifically, the stirring process adopts a segmented stirring method, first stirring at a speed of 300 rpm for 15 minutes to initially mix the ingredients, and then increasing the speed to 600 rpm for 45 minutes to ensure that the ingredients are fully mixed. During the stirring process, the temperature is controlled at 30°C-40°C to avoid excessive temperature affecting product quality.

[0032] In this embodiment: first stir at a speed of 300 rpm for 15 minutes to preliminarily mix the ingredients, laying the foundation for subsequent sufficient stirring. Then increase the speed to 600 rpm and stir for 45 minutes to ensure that the ingredients are fully mixed. This segmented stirring method not only improves the stirring efficiency, but also avoids the problem of uneven ingredients caused by stirring too fast or too slow. During the stirring process, the temperature is controlled at 30°C-40°C. This temperature range can not only ensure that the activity of each ingredient is not affected, but also avoid the impact of excessive temperature on product quality. Through precise temperature control and reasonable stirring methods, the various ingredients of the skin care product can be fully integrated to exert the best effect. At the same time, this preparation process also improves the stability and consistency of the product, providing consumers with high-quality skin care products.

[0033] Specifically, after homogenization, the skin care products are sterilized using high-temperature instantaneous sterilization at 120℃-130℃ for 3-5 seconds to ensure the safety and stability of the products. The microbial indicators of the products after sterilization meet the relevant standards, such as the total colony count not exceeding 100CFU / g, and the total number of molds and yeasts not exceeding 50CFU / g.

[0034] In this embodiment: sterilization at a temperature of 120℃-130℃ for 3-5 seconds can quickly and effectively kill microorganisms in the product, ensuring the safety and stability of the product. This sterilization method is short in time and high in temperature, and can achieve a good sterilization effect without destroying the ingredients and efficacy of the product. The microbial indicators of the product after sterilization meet the relevant standards, such as the total colony count not exceeding 100CFU / g, and the total number of molds and yeasts not exceeding 50CFU / g, providing consumers with safe and reliable skin care products. At the same time, high-temperature instantaneous sterilization also helps to maintain the freshness of the product and the stability of the active ingredients, and extend the shelf life of the product. This sterilization step is a key link in ensuring the quality of skin care products and provides a strong guarantee for the safety of consumers.

[0035] Specifically, during storage, the skin care product should be placed in an environment with a temperature of 10°C-20°C and a relative humidity not exceeding 55%. The storage container should be made of specific materials and sealed to prevent the product from being affected by external factors and deteriorating.

[0036] In this embodiment: Placing the skin care product in an environment with a temperature of 10°C-20°C and a relative humidity not exceeding 55% can effectively prevent the product from being affected by temperature and humidity and deteriorating. Under such suitable storage conditions, the active ingredients in the product can remain stable and extend the service life of the product. The storage container adopts specific materials and sealing methods, which can further prevent the product from being affected by external factors, such as air, light and moisture. Containers made of specific materials can block the entry of ultraviolet rays and oxygen, protecting the active ingredients in the product from oxidation. The sealing method can prevent the intrusion of moisture and dust, ensuring the purity of the product. By strictly controlling the storage conditions and selecting suitable storage containers, it can be ensured that the skin care products always maintain good quality and efficacy during the storage process.

[0037] Specifically, in addition to being used for daily facial care, this skin care product can also be used for skin care of other parts of the body such as the neck and hands. When using it, the method and dosage can be adjusted according to the skin characteristics of different parts to achieve improvement of the skin of the whole body.

[0038] In the present embodiment: the skin care product can be used for skin care of other parts of the body such as neck and hands in addition to daily facial care, which greatly expands the scope of use of the product. The skin of different parts has different characteristics, for example, the skin of the neck is relatively weak, and the skin of the hands is often in contact with the external environment and is easy to dry. According to the skin characteristics of different parts, the use method and dosage are adjusted to better meet the consumer's demand for improvement of the whole body skin. This multifunctional skin care product provides consumers with a more convenient and comprehensive skin care solution, without the need to purchase a variety of different skin care products, saving time and money. At the same time, the comprehensive efficacy of the product can provide anti-oxidation, whitening, moisturizing, wrinkle reduction, soothing sensitivity and repairing damaged skin for the whole body skin, making the consumer's skin healthier and more beautiful.

[0039] The working principle and use process of the present invention:

[0040] First, thioneine solution is prepared, and a process of fermentation and extraction from natural fungi is adopted, and natural fungi are inoculated in a specific culture medium, and the temperature is controlled to be fermented for a certain time under the condition of 25 DEG C-30 DEG C and pH value of 6-7. After the fermentation is completed, a specific solvent is adopted for extraction, and after extraction, thioneine solution is obtained through filtering, concentration and other steps, and then treated with a stabilizer with a mass fraction of 0.5%-1.5%, and its stability and solubility are improved, and thioneine is effectively prevented from being degraded in the solution, and it is ensured that the antioxidant effect continues to play. Meanwhile, a nicotinamide solution is prepared, and the nicotinamide solution is dissolved in the nicotinamide. The mixture is dissolved in an appropriate amount of deionized water, and 0.2%-0.4% of natural antioxidant tea polyphenols are added to further improve the stability of nicotinamide. The stirring process adopts a segmented stirring method, first stirring at a speed of 300 rpm for 15 minutes to initially mix the components, and then increasing the speed to 600 rpm for 45 minutes. During the stirring process, the temperature is controlled at 30°C-40°C to ensure that the components are fully mixed and uniform and to avoid excessive temperature affecting the product quality. Then, the two pretreated solutions are mixed according to a specific ratio of ergothioneine to nicotinamide of 1:2-1:6. The mixed solution is mixed to form a mixed solution, and skin care base ingredients are added to the mixed solution, including 2%-10% by mass of glycerin, 0.1%-0.8% of sodium hyaluronate and other moisturizing ingredients, 4%-12% by mass of natural oils or synthetic oils and other emollients, and 1%-4% by mass of non-ionic emulsifiers and other emulsifiers, and the mixed solution is stirred at a specific stirring speed of 400-1000 rpm for 20-90 minutes, and then homogenized at a homogenization pressure of 8-25 MPa for 8-25 minutes to fully mix the ingredients, and then, a high-temperature instantaneous sterilization method is used. Sterilize at 120℃-130℃ for 3-5 seconds to ensure the safety and stability of the product and make its microbial indicators meet the relevant standards. During storage, the sterilized product should be placed in an environment with a temperature of 10℃-20℃ and a relative humidity not exceeding 55%. The storage container is made of specific materials and sealed to prevent the product from being affected by external factors and deteriorating. In addition to daily facial care, this skin care product can also be used for skin care of other parts of the body such as the neck and hands. When using it, the method and dosage can be adjusted according to the characteristics of the skin of different parts to achieve improvement of the skin of the whole body.

[0041] Finally, it should be noted that the above are only preferred embodiments of the present invention and are not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned embodiments or replace some of the technical features therein by equivalents. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.

Claims

1. A method for preparing a skin care product rich in ergothioneine and niacinamide, characterized in that, The following steps are involved: Step 1: preparing thioneine solution and nicotinamide solution respectively, treating the thioneine solution with a stabilizer having a mass fraction of 0.5%-1.5% to improve its stability and solubility; adjusting the pH value of the nicotinamide solution to 5-7; Step 2: mixing the pretreated ergothioneine solution and the nicotinamide solution according to a specific ratio of 1:2-1:6 in which the mass ratio of ergothioneine to nicotinamide is 1:2 to 1:6 to form a mixed solution; Step 3: Add skin care base ingredients to the mixed solution, wherein the moisturizer is 2%-10% by mass of glycerin, 0.1%-0.8% by mass of sodium hyaluronate and other suitable moisturizing ingredients, the emollient is 4%-12% by mass of natural oil or synthetic oil, and the emulsifier is 1%-4% by mass of non-ionic emulsifier or other suitable emulsifier, and stir at a specific stirring speed of 400-1000 rpm for 20-90 minutes, and then homogenize at a homogenization pressure of 8-25 MPa for 8-25 minutes to obtain a skin care product rich in ergothioneine and niacinamide. The skin care product can be used in a variety of skin condition improvement scenarios, including but not limited to anti-oxidation, whitening, moisturizing, wrinkle reduction, soothing sensitivity, repairing damaged skin, etc.

2. A method for preparing a skin care product rich in ergothioneine and niacinamide according to claim 1, characterized in that, The preparation of the ergothioneine solution adopts a process of fermentation extraction from natural fungi. After specific fermentation condition control and extraction steps, the extraction rate is not less than 55%. In the extraction process, the natural fungi are first inoculated in a specific culture medium, fermented for a certain time under the conditions of a temperature of 25° C.-30° C. and a pH value of 6-7, and then extracted with a specific solvent. After extraction, the ergothioneine solution is obtained through filtering, concentration and other steps.

3. A method for preparing a skin care product rich in ergothioneine and niacinamide according to claim 2, characterized in that, During the preparation of the nicotinamide solution, 0.2%-0.4% by mass of tea polyphenols, a natural antioxidant, is added to further improve the stability of nicotinamide. During the preparation, nicotinamide is dissolved in an appropriate amount of deionized water, and after tea polyphenols are added, the solution is stirred at a specific temperature until it is completely dissolved.

4. A method for preparing a skin care product rich in ergothioneine and niacinamide according to claim 3, characterized in that, The stirring process adopts a segmented stirring method, first stirring at a speed of 300 rpm for 15 minutes to initially mix the ingredients, and then increasing the speed to 600 rpm for 45 minutes to ensure that the ingredients are fully mixed. During the stirring process, the temperature is controlled at 30°C-40°C to avoid excessive temperature affecting product quality.

5. A method for preparing a skin care product rich in ergothioneine and niacinamide according to claim 4, characterized in that, After the homogenization treatment, the skin care product is sterilized by high temperature instantaneous sterilization at a temperature of 120°C-130°C for 3-5 seconds to ensure the safety and stability of the product. The microbial indicators of the product after sterilization meet the relevant standards, such as the total colony count not exceeding 100 CFU / g, and the total number of molds and yeasts not exceeding 50 CFU / g.

6. A method for preparing a skin care product rich in ergothioneine and niacinamide according to claim 5, characterized in that, During storage, this skin care product should be placed in an environment with a temperature of 10℃-20℃ and a relative humidity not exceeding 55%. The storage container should be made of specific materials and sealed to prevent the product from being affected by external factors and deteriorating.

7. The use of a skin care product rich in ergothioneine and niacinamide according to claim 6, characterized in that, In addition to daily facial care, this skin care product can also be used for skin care of other parts of the body such as the neck and hands. When using it, the method and dosage can be adjusted according to the skin characteristics of different parts to achieve improvement of the skin of the whole body.