Universal scald ointment or powder and preparation method thereof

Abstract

The invention discloses general type scald ointment or powder and a preparation method thereof.The general type scald ointment or powder comprises traditional Chinese medicine components and western medicine components, the traditional Chinese medicine components comprise, by mass, 20-40 parts of rheum officinale, 20-40 parts of gypsum, 24-28 parts of lithospermum and 0.1-5 parts of borax, and the western medicine components comprise, by mass, 20-40 parts of rheum officinale, 20-40 parts of gypsum, 24-28 parts of lithospermum and 0.1-5 parts of borax. The general scald ointment or powder comprises the following components in parts by mass: 80-85 parts of traditional Chinese medicine components and 15-20 parts of western medicine components, and the western medicine components are metronidazole tablets. The general ointment or powder for burns and scalds has the advantages of fast pain relieving, fast healing and low cost.

Description

Technical Field

[0001] The invention relates to a universal scald ointment or powder and a preparation method thereof. Background Art

[0002] Skin scald is a common disease, mainly caused by improper operation of children or adults in life or work, skin contact with hot and wet liquid or objects, skin damage, pain, blisters or skin charring. Its incidence rate is about 2% in the community. At present, hospitals and pharmacies can provide burns and scalds treatment drugs such as burn moistening ointment, Jingwanhong scald ointment, strong burn ointment, etc. Its efficacy is uncertain and wound infection is easy. Summary of the invention

[0003] The object of the present invention is to provide a universal burn ointment or powder to solve the problems raised in the above background technology. To achieve the above object, the present invention provides the following technical solutions:

[0004] A universal burn ointment or powder comprises Chinese medicinal ingredients and western medicinal ingredients, wherein the Chinese medicinal ingredients comprise rhubarb, gypsum, lithospermum officinale and borax, wherein the weight proportions of each component in the Chinese medicinal ingredients are as follows: 20-40 parts of rhubarb, 20-40 parts of gypsum, 24-28 parts of lithospermum officinale and 0.1-5 parts of borax; and the weight proportions of the Chinese medicinal ingredients and the western medicinal ingredients in the universal burn ointment or powder are as follows: 80-85 parts of the Chinese medicinal ingredients and 15-20 parts of the western medicinal ingredients, wherein the western medicinal ingredient is metronidazole tablets.

[0005] Furthermore, the mass proportions of each component in the traditional Chinese medicine are as follows: 30 parts of rhubarb, 30 parts of gypsum, 16 parts of lithospermum officinale and 1 part of borax.

[0006] Furthermore, the weight proportions of Chinese medicinal ingredients and Western medicinal ingredients are: 82.5 parts of Chinese medicinal ingredients and 17.5 parts of Western medicinal ingredients.

[0007] The present invention also provides a method for preparing a universal burn ointment or powder, comprising the following steps:

[0008] S1: Grind the Chinese medicinal ingredients: rhubarb, gypsum, and lithospermum into fine powder using a powder grinder, wherein the mass proportions of each component in the Chinese medicinal ingredients are: 20-40 parts of rhubarb, 20-40 parts of gypsum, 24-28 parts of lithospermum and 0.1-5 parts of borax; and the western medicinal ingredient: metronidazole tablets are ground into fine powder.

[0009] S2: 80-85 parts of the Chinese medicinal ingredients and 15-20 parts of the Western medicinal ingredients are blended and filtered.

[0010] Furthermore, the filtration is performed using sterile gauze filtration or bamboo mesh.

[0011] Furthermore, the bamboo screen has a mesh size of 500.

[0012] Beneficial effects: the universal burn ointment or powder of the present invention has quick pain relief, fast recovery and low cost. DETAILED DESCRIPTION

[0013] The technical solutions in the embodiments of the present invention are described clearly and completely below. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0014] The invention provides a universal burn ointment or powder, comprising Chinese medicinal ingredients and western medicinal ingredients. The Chinese medicinal ingredients comprise rhubarb, gypsum, lithospermum officinale and borax, wherein the weight proportions of each component in the Chinese medicinal ingredients are as follows: 20-40 parts of rhubarb, 20-40 parts of gypsum, 24-28 parts of lithospermum officinale and 0.1-5 parts of borax; and the weight proportions of the Chinese medicinal ingredients and the western medicinal ingredients in the universal burn ointment or powder are as follows: 80-85 parts of the Chinese medicinal ingredients and 15-20 parts of the western medicinal ingredients, and the western medicinal ingredient is a metronidazole tablet.

[0015] The present invention also provides a method for preparing a universal burn ointment or powder, comprising the following steps:

[0016] S1: Grind the Chinese medicinal ingredients: rhubarb, gypsum, and lithospermum into fine powder using a powder grinder. The mass proportions of each component in the Chinese medicinal ingredients are: 20-40 parts of rhubarb, 20-40 parts of gypsum, 24-28 parts of lithospermum, and 0.1-5 parts of borax. The western medicinal ingredient: metronidazole tablets are ground into fine powder.

[0017] S2: 80-85 parts of Chinese medicinal ingredients and 15-20 parts of Western medicinal ingredients are mixed and filtered, and the filtration is performed by sterile gauze filtration or bamboo sieve with a mesh size of 500.

[0018] In order to verify the effect of the above universal burn ointment or powder, the following experiment was conducted:

[0019] Example 1

[0020] Prepare the Chinese medicine ointment according to the following method:

[0021] 1. Weigh the following Chinese medicinal materials: 100 g rhubarb, 100 g gypsum, 80 g lithospermum, and 5 g borax.

[0022] 2. Weigh 57 g of metronidazole.

[0023] 3. Finely grind the above Chinese medicinal materials in a grinder at room temperature to a size of 500 mesh.

[0024] 4. Grind the metronidazole tablets into powder to a size of 500 mesh.

[0025] 5. The fine powder of the above-mentioned Chinese medicinal materials is blended into a paste with metronidazole to obtain a Chinese medicinal ointment.

[0026] Example 2

[0027] Prepare the Chinese medicine ointment according to the following method:

[0028] 1. Weigh the following Chinese medicinal materials: 85.5 g rhubarb, 114 g gypsum, 80 g lithospermum, and 5 g borax.

[0029] 2. Weigh 57g of metronidazole

[0030] 3. Finely grind the above Chinese medicinal materials in a large grinder at room temperature to 500 mesh.

[0031] 4. Grind the metronidazole tablets into powder to a size of 500 mesh.

[0032] 5. The fine powder of the above-mentioned Chinese medicinal materials is blended into a paste with metronidazole to obtain a Chinese medicinal ointment.

[0033] Example 3

[0034] Prepare the Chinese medicine ointment according to the following method:

[0035] 1. Weigh the following Chinese medicinal materials: 86 grams of rhubarb, 114 grams of gypsum, 71 grams of lithospermum, and 14 grams of borax.

[0036] 2. Weigh 50 g of metronidazole.

[0037] 3. Finely grind the above Chinese medicinal materials in a large grinder at room temperature to 500 mesh.

[0038] 4. Grind the metronidazole tablets into powder to a size of 500 mesh.

[0039] 5. The fine powder of the above-mentioned Chinese medicinal materials is blended into a paste with metronidazole to obtain a Chinese medicinal ointment.

[0040] Example 4

[0041] Prepare the Chinese medicine ointment according to the following method:

[0042] 1. Weigh the following Chinese medicinal materials: 100 g rhubarb, 100 g gypsum, 80 g lithospermum, and 5 g borax.

[0043] 2. Weigh 71 g of metronidazole;

[0044] 3. Finely grind the above Chinese medicinal materials in a grinder at room temperature to a size of 500 mesh.

[0045] 4. Grind the metronidazole tablets into powder to a size of 500 mesh.

[0046] 5. The fine powder of the above-mentioned Chinese medicinal materials is blended into a paste with metronidazole to obtain a Chinese medicinal ointment.

[0047] Example 5

[0048] 1. Weigh the following Chinese medicinal materials: 100 g rhubarb, 100 g gypsum, 80 g lithospermum, and 5 g borax.

[0049] 2. Weigh 48 g of metronidazole;

[0050] 3. Finely grind the above Chinese medicinal materials in a grinder at room temperature to a size of 500 mesh.

[0051] 4. Grind the metronidazole tablets into powder to a size of 500 mesh.

[0052] 5. The fine powder of the above-mentioned Chinese medicinal materials is blended into a paste with metronidazole to obtain a Chinese medicinal ointment.

[0053] Use the Chinese medicine ointment prepared last time.

[0054] The above prepared Chinese medicine ointment was subjected to an experiment, and the experimental steps are as follows:

[0055] (1) Establishment of rat model of scald:

[0056] 180 g, 6-8 weeks old male SD rats were used and adapted to the environment for 3 days. The lights were turned on at 7 am and turned off at 7 pm to establish a normal schedule for the rats.

[0057] A scald blister model was constructed in SD rats. The electric constant temperature water bath test tube method was used. The back of the rat was depilated and placed close to the mouth of a test tube filled with 100 degrees Celsius water. The rats were left to stand for 16 seconds and macroscopic photography was performed after the operation.

[0058] After modeling, normal skin is ruddy and wrinkle-free; after burns and blistering, the wound skin immediately turns white, and there is peeling at the border of the burn area.

[0059] (2) Experimental purpose:

[0060] Whether homemade Chinese herbal ointment has a therapeutic effect on the burn blister model.

[0061] (3) Experimental results:

[0062] a. Macroscopic results of homemade Chinese medicine ointment treatment:

[0063] The wounds on the back of SD rats with successful modeling were randomly divided into a control group and a Chinese medicine ointment group. The control group was given Jingwanhong burn ointment; the Chinese medicine ointment group was given a homemade Chinese medicine ointment, with the medicine covering the wound as the basis; once a day, until the wound heals. The changes in the skin over time are shown in the following table:

[0064]

[0065]

[0066] It was found that both the homemade Chinese herbal ointment and Jingwanhong burn ointment had a therapeutic effect on the burn blister model. At the same time, through macroscopic observation, it was preliminarily judged that the efficacy of the homemade Chinese herbal ointment was better than that of Jingwanhong burn ointment in treating the burn blister model.

[0067] When used on humans, apply a thin layer of medical vaseline or vegetable oil on the wound, then sprinkle the reserved powder on the wound without bandaging. If the patient is more than 6 hours old or has skin infection, surgical disinfection is required before using the powder. If the wound is large or seriously infected, change the dressing twice a day, and if the wound is small or slightly infected, change the dressing once a day. In practice, it is found that the cure rate of burns and scalds can reach 98% by using the above powder.

[0068] Among them, rhubarb has the functions of clearing away heat and detoxifying, and removing fire poison; gypsum has the effects of clearing heat and removing fire poison; lithospermum has the effects of clearing heat and cooling blood, and detoxifying; borax has the effects of astringency and promoting wound healing; Chinese medicine has an antiseptic effect; and the Western medicine metronidazole has an anti-inflammatory effect on the skin surface and purulent infections, with obvious therapeutic effects.

[0069] The above is only a preferred embodiment of the present invention, and does not limit the present invention in any form. The protection scope of the present invention shall be subject to the protection scope of the claims. Although the present invention has been disclosed as a preferred embodiment as above, it is not used to limit the present invention. Any technician familiar with this profession can make some changes or modifications to equivalent embodiments of equivalent changes using the technical content disclosed above without departing from the scope of the technical solution of the present invention. However, any simple modification, equivalent change and modification made to the above embodiments based on the technical essence of the present invention without departing from the content of the technical solution of the present invention still falls within the scope of the technical solution of the present invention.

Claims

1. A universal burn ointment or powder, comprising Chinese medicine ingredients and Western medicine ingredients, characterized in that: The Chinese medicinal ingredients include rhubarb, gypsum, lithospermum and borax, wherein the weight proportions of each component in the Chinese medicinal ingredients are: 20-40 parts of rhubarb, 20-40 parts of gypsum, 24-28 parts of lithospermum and 0.1-5 parts of borax; the weight proportions of the Chinese medicinal ingredients and the western medicinal ingredients in the universal burn ointment or powder are: 80-85 parts of the Chinese medicinal ingredients and 15-20 parts of the western medicinal ingredients, and the western medicinal ingredient is metronidazole tablets.

2. A universal burn ointment or powder according to claim 1, characterized in that: in, The mass proportions of each component in the traditional Chinese medicine are as follows: 30 parts of rhubarb, 30 parts of gypsum, 16 parts of lithospermum officinale and 1 part of borax.

3. A universal burn ointment or powder according to claim 1, characterized in that: The mass proportions of Chinese medicine ingredients and Western medicine ingredients are: 82.5 parts of Chinese medicine ingredients and 17.5 parts of Western medicine ingredients.

4. A method for preparing a universal burn ointment or powder, characterized in that: The following steps are involved: S1: Grind the Chinese medicinal ingredients: rhubarb, gypsum, and lithospermum into fine powder using a powder grinder, wherein the mass proportions of each component in the Chinese medicinal ingredients are: 20-40 parts of rhubarb, 20-40 parts of gypsum, 24-28 parts of lithospermum and 0.1-5 parts of borax; and the western medicinal ingredient: metronidazole tablets are ground into fine powder. S2: 80-85 parts of the Chinese medicinal ingredients and 15-20 parts of the Western medicinal ingredients are blended and filtered.

5. The preparation method according to claim 2, characterized in that: Filter using sterile gauze or bamboo sieve.

6. The preparation method according to claim 2, characterized in that: The bamboo sieve has a mesh size of 500.

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