Anti-hair-loss and anti-dandruff shampoo and preparation method thereof

Abstract

The invention relates to the technical field of anti-hair-loss shampoo, and discloses anti-hair-loss and anti-dandruff shampoo and a preparation method thereof.The anti-hair-loss and anti-dandruff shampoo is prepared from, by weight, 3%-10% of anti-hair-loss agents, 15%-30% of surfactants, 2%-8% of anti-dandruff agents, 5%-15% of humectants, 2%-6% of conditioners, 0.5%-2% of thickening agents, 0.1%-0.5% of preservatives, 0.1%-0.3% of essence and the balance water. The whole formula adopts various mild components, has no irritation to scalp and hair, and is suitable for long-term use. The preparation method disclosed by the invention is reasonable in process, the raw materials can be ensured to be fully and uniformly mixed and play the best effect, the produced shampoo is good in stability and not easy to layer and deteriorate in the storage and use processes, an efficient, safe and stable anti-hair-loss and anti-dandruff shampoo solution is provided for consumers, and the anti-hair-loss and anti-dandruff shampoo is worthy of popularization and application. Wide market application prospects and good social benefits are realized.

Description

Technical Field

[0001] The invention relates to the technical field of anti-hair loss shampoo, in particular to an anti-hair loss and anti-dandruff shampoo and a preparation method thereof. Background Art

[0002] Hair health has always been the focus of people's attention. Hair loss and dandruff problems trouble many consumers. Hair loss not only affects personal image, but may also have a negative impact on psychology; dandruff problems can cause scalp itching and discomfort, seriously affecting the quality of life.

[0003] In modern life, the factors that cause hair loss and dandruff are becoming increasingly complex and diverse. In terms of environmental factors, air pollution has intensified. Harmful substances in the air, such as dust and heavy metals, are easily attached to the scalp and hair, irritating the scalp, affecting the health of hair follicles, and then causing hair loss. At the same time, it also provides conditions for the growth of microorganisms such as Malassezia. Over-reproduction of Malassezia can lead to excessive proliferation of the scalp stratum corneum and produce dandruff. Changes in lifestyle have also had a significant impact on hair health. Modern people are under great work pressure, and long-term mental stress can lead to endocrine disorders and affect hormone balance. Among them, abnormally high androgen levels may lead to androgenic alopecia. Frequent use of heat styling tools, such as hair dryers and curling irons, high temperatures can damage the keratin of the hair, making the hair fragile and easy to break. At the same time, it can also damage the scalp, destroy the barrier function of the scalp, and increase the risk of hair loss and dandruff. An unreasonable diet structure, excessive intake of high-sugar, high-fat, and spicy foods, and a lack of nutrients such as vitamins and minerals will affect the normal growth and metabolism of hair, causing dry and easy-to-fall hair, imbalanced scalp oil secretion, and dandruff problems.

[0004] There are many kinds of shampoo products on the market, but products for hair loss and dandruff problems often have problems such as single function and insignificant effect. Some anti-dandruff shampoos can only temporarily relieve dandruff symptoms, and cannot fundamentally regulate the balance of scalp microorganisms. The effect will gradually weaken with long-term use. The active ingredients of anti-hair loss shampoo may be difficult to penetrate into the hair follicles to play a role, or the residence time on the scalp is short, and it is unable to continuously nourish the hair follicles, and the anti-hair loss effect is not ideal. In addition, some products may contain irritating chemicals, and long-term use will cause further damage to the scalp and hair. Therefore, consumers are in urgent need of a shampoo product that can effectively prevent hair loss and thoroughly remove dandruff, and is mild and non-irritating to the scalp and hair. At the same time, as consumers' pursuit of natural, healthy and environmentally friendly products continues to increase, the development of a shampoo with good anti-hair loss and anti-dandruff effects using mild ingredients such as natural plant extracts has important market prospects and social significance. Summary of the invention

[0005] 1. Technical issues to be resolved

[0006] In view of the deficiencies in the prior art, the present invention provides an anti-dandruff shampoo and a preparation method thereof.

[0007] (II) Technical solution

[0008] An anti-dandruff shampoo is made from the following raw materials in percentage by weight:

[0009] 3-10% of an anti-hair loss agent, wherein the anti-hair loss agent is a mixture of saw palmetto extract, ginseng extract and Polygonum multiflorum extract encapsulated by nanoliposomes in a weight ratio of 2-4:1-3:1-2. The preparation method of the Polygonum multiflorum extract encapsulated by nanoliposomes is as follows: the Polygonum multiflorum extract is mixed with phospholipids and cholesterol in a weight ratio of 1:2-3:0.5-1, an appropriate amount of organic solvent is added to dissolve, the organic solvent is removed by rotary evaporation under reduced pressure at 40-60° C. to form a lipid film, and then a phosphate buffer solution with a pH value of 6-7 is added, and the mixture is treated under ultrasonic conditions with a power of 100-300 W and a frequency of 20-40 kHz for 10-30 minutes to obtain the Polygonum multiflorum extract encapsulated by nanoliposomes;

[0010] 15-30% surfactant, wherein the surfactant is a mixture of sodium laureth sulfate, sodium lauroyl sarcosinate and cocamidopropyl betaine in a weight ratio of 3-5:1-2:1-3;

[0011] 2-8% of an anti-dandruff agent, wherein the anti-dandruff agent is one or more of piroctone olamine, salicylic acid and ketoconazole;

[0012] 5-15% moisturizing agent, wherein the moisturizing agent is a mixture of sodium hyaluronate, glycerin and panthenol in a weight ratio of 1-3:2-5:1-2;

[0013] 2-6% of a conditioning agent, wherein the conditioning agent is a mixture of polyquaternium-10, guar hydroxypropyltrimonium chloride and hydrolyzed keratin in a weight ratio of 1-2:1-3:1-2;

[0014] 0.5-2% thickener, wherein the thickener is one or more of sodium chloride, carbomer and hydroxyethyl cellulose;

[0015] 0.1-0.5% preservative, wherein the preservative is one or more of phenoxyethanol, methylisothiazolinone and sodium benzoate;

[0016] Fragrance 0.1-0.3%;

[0017] The balance is water.

[0018] Preferably, the mass fraction of the saw palmetto extract in the anti-hair loss agent is 40-50%, the mass fraction of the ginseng extract is 30-40%, and the mass fraction of the Polygonum multiflorum extract encapsulated by nanoliposomes is 20-30%.

[0019] Preferably, in the surfactant, the mass fraction of sodium laureth sulfate is 50-60%, the mass fraction of sodium lauroyl sarcosinate is 20-30%, and the mass fraction of cocamidopropyl betaine is 20-30%.

[0020] Preferably, the mass ratio of piroctone olamine salt, salicylic acid and ketoconazole in the anti-dandruff agent is 1-3:1-2:0-1.

[0021] Preferably, the mass fraction of sodium hyaluronate in the moisturizing agent is 20-30%, the mass fraction of glycerol is 40-50%, and the mass fraction of panthenol is 20-30%.

[0022] Preferably, in the conditioner, the mass fraction of polyquaternium-10 is 30-40%, the mass fraction of guar hydroxypropyltrimethylammonium chloride is 30-40%, and the mass fraction of hydrolyzed keratin is 20-30%.

[0023] Preferably, the mass ratio of sodium chloride, carbomer and hydroxyethyl cellulose in the thickener is 1-2:0-1:0-1.

[0024] Preferably, the mass fraction of phenoxyethanol in the preservative is 50-70%, the mass fraction of methylisothiazolinone is 20-30%, and the mass fraction of sodium benzoate is 10-20%.

[0025] Preferably, the method comprises the following steps:

[0026] S1: Raw material preparation

[0027] Weigh each raw material according to the weight percentage described in claim 1 to ensure that the purity of each raw material meets the relevant standards. The purity of sodium laureth sulfate in the surfactant is not less than 95%, the purity of sodium lauroyl sarcosinate is not less than 90%, and the purity of cocamidopropyl betaine is not less than 90%; the purity of piroctone olamine salt in the anti-dandruff agent is not less than 98%, the purity of salicylic acid is not less than 99%, and the purity of ketoconazole is not less than 95%; the content of effective ingredients of saw palmetto extract in the anti-hair loss agent is not less than 40%, the content of effective ingredients of ginseng extract is not less than 30%, and the content of effective ingredients of Polygonum multiflorum extract in Polygonum multiflorum encapsulated by nanoliposomes is not less than 10%. The content of active ingredients in the moisturizer shall not be less than 20%; the purity of sodium hyaluronate in the moisturizer shall not be less than 90%, the purity of glycerin shall not be less than 95%, and the purity of panthenol shall not be less than 95%; the purity of polyquaternium-10 in the conditioner shall not be less than 90%, the purity of guar hydroxypropyltrimonium chloride shall not be less than 90%, and the purity of hydrolyzed keratin shall not be less than 85%; the purity of sodium chloride in the thickener shall not be less than 99%, the purity of carbomer shall not be less than 95%, and the purity of hydroxyethyl cellulose shall not be less than 90%; the purity of phenoxyethanol in the preservative shall not be less than 99%, the purity of methylisothiazolinone shall not be less than 95%, and the purity of sodium benzoate shall not be less than 99%;

[0028] S2: Aqueous Phase Preparation

[0029] Add the weighed water into the reactor, heat to 40-50°C, add the moisturizer, thickener and preservative in sequence under the condition of stirring at a speed of 200-300r / min, and stir for 15-25min until they are completely dissolved to form a water phase;

[0030] S3: Oil phase preparation

[0031] Heat the surfactant at 40-50°C until it is completely melted, add the conditioning agent under the condition of stirring at a speed of 150-250r / min, and stir for 10-20min to form an oil phase;

[0032] S4: Mixing and emulsification

[0033] Slowly add the oil phase into the water phase, and carry out emulsification reaction at a stirring speed of 250-350r / min for 15-25min to form an emulsion;

[0034] S5: Adding active ingredients

[0035] When the emulsion temperature drops to 35-45°C, add the anti-dandruff agent and anti-shedding agent in sequence at a stirring speed of 100-200r / min, and stir for 10-20 minutes to make them evenly dispersed;

[0036] S6: Perfumery

[0037] Finally, add the essence and stir for 5-10 minutes to obtain the anti-dandruff shampoo.

[0038] Preferably, in the step of preparing the S2 aqueous phase, water is heated by indirect heating, such as heating by passing hot water or steam through a jacketed reactor to ensure uniform heating and avoid local overheating;

[0039] In the S3 oil phase preparation step, a constant temperature heating device is used during the heating and melting process of the surfactant to control the temperature fluctuation range within ±1°C to ensure the stability of the surfactant quality;

[0040] In the S4 mixing and emulsification step, ultrasound-assisted emulsification can be used during the emulsification reaction, with an ultrasound frequency of 20-40 kHz and an ultrasound time of 5-10 min to improve the emulsification effect and make the shampoo system more stable;

[0041] In the step of adding active ingredients in S5, the anti-dandruff agent and the anti-shedding agent are pre-dispersed before being added, that is, the anti-dandruff agent and the anti-shedding agent are respectively mixed with a small amount of water or glycerin to form a uniform dispersion and then added to the emulsion to improve its dispersibility and stability;

[0042] In the S6 perfume adjustment step, the fragrance is first mixed with an appropriate amount of surfactant before being added to form a fragrance emulsion, which is then added to the system to improve the stability and fragrance retention effect of the fragrance.

[0043] (III) Beneficial technical effects

[0044] In terms of hair loss prevention, the saw palmetto extract, ginseng extract and Polygonum multiflorum extract encapsulated by nanoliposomes in the anti-hair loss agent work synergistically. Saw palmetto extract can inhibit the binding of androgen to hair follicle receptors, reduce the adverse effects of androgen on hair follicles, and thus reduce the risk of hair loss; ginseng extract is rich in various nutrients, which can nourish hair follicles, promote the metabolism of hair follicle cells, enhance the vitality of hair follicles, and provide a good environment for hair growth; Polygonum multiflorum extract encapsulated by nanoliposomes, liposomes as carriers can improve the stability and transdermal absorption effect of Polygonum multiflorum extract, the active ingredients in Polygonum multiflorum extract can penetrate into the hair follicles, regulate the growth cycle of hair follicles, promote hair growth, effectively reduce the amount of hair loss, and make the hair thicker and healthier.

[0045] In terms of anti-dandruff efficacy, piroctone olamine salt, salicylic acid and ketoconazole (optional) in the anti-dandruff agent work against the main factors that cause dandruff, such as Malassezia. Piroctone olamine salt can effectively inhibit the growth and reproduction of Malassezia, reducing the production of dandruff from the root; salicylic acid has a keratin regulating effect, which can promote the normal metabolism of the scalp stratum corneum, remove aging keratin, and make the scalp more refreshing; ketoconazole has a strong anti-fungal ability, further inhibiting the growth of scalp fungi, eliminating dandruff, relieving scalp itching symptoms, and keeping the scalp clean and healthy.

[0046] Sodium hyaluronate, glycerin and panthenol in the moisturizer can replenish moisture to the scalp and hair, prevent dry scalp, maintain moisture balance in the hair, make hair smoother and more shiny, and reduce hair breakage caused by dryness. Polyquaternium-10, guar hydroxypropyltrimonium chloride and hydrolyzed keratin in the conditioner can improve the combing performance of hair, repair damaged hair, enhance hair toughness and reduce hair damage during combing.

[0047] The whole formula adopts a variety of mild ingredients, is non-irritating to the scalp and hair, and is suitable for long-term use. At the same time, the preparation method of the present invention has a reasonable process, can ensure that the raw materials are fully mixed and evenly, play the best effect, the produced shampoo has good stability, is not easy to stratify and deteriorate during storage and use, and provides consumers with an efficient, safe and stable anti-dandruff shampoo solution, which has broad market application prospects and good social benefits. DETAILED DESCRIPTION

[0048] Example 1

[0049] Raw material preparation

[0050] Surfactants: Sodium laureth sulfate 12g (60% of the total surfactants), sodium lauroyl sarcosinate 4g (20%), cocamidopropyl betaine 4g (20%).

[0051] Anti-dandruff agent: piroctone olamine salt 4g, salicylic acid 2g.

[0052] Anti-hair loss agent: 4g of saw palmetto extract (accounting for 40% of the total amount of the anti-hair loss agent), 3g of ginseng extract (accounting for 30%), and 3g of Polygonum multiflorum extract encapsulated by nanoliposomes (accounting for 30%). The preparation method of the Polygonum multiflorum extract encapsulated by nanoliposomes is as follows: take 1g of Polygonum multiflorum extract, 2.5g of phospholipids, and 0.75g of cholesterol, mix them, add 30mL of ethanol to dissolve them, remove the ethanol by rotary evaporation under reduced pressure at 50°C to form a lipid film, add a phosphate buffer solution with a pH value of 6.5, and treat it under ultrasound with a power of 200W and a frequency of 30kHz for 20 minutes to obtain it.

[0053] Moisturizer: Sodium hyaluronate 3g (20% of the total moisturizer), glycerin 6g (40%), panthenol 3g (20%).

[0054] Conditioning agent: Polyquaternium-10 2g (accounting for 33.3% of the total conditioning agent), guar hydroxypropyltrimonium chloride 2g (accounting for 33.3%), hydrolyzed keratin 1g (accounting for 16.7%).

[0055] Thickener: Sodium chloride 1g.

[0056] Preservatives: phenoxyethanol 0.3g (accounting for 60% of the total preservatives), methylisothiazolinone 0.15g (accounting for 30%), sodium benzoate 0.05g (accounting for 10%).

[0057] 0.2g of flavor.

[0058] 60.3g of water.

[0059] Preparation process

[0060] S1: Weigh each raw material according to the above weight to ensure that the purity of each raw material meets the requirements.

[0061] S2: Add water into the reactor, heat to 45°C, add the moisturizer, thickener and preservative in sequence under stirring at 250 r / min, and stir for 20 minutes until they are completely dissolved to form an aqueous phase.

[0062] S3: Heat the surfactant at 45°C to melt, add the conditioning agent while stirring at 200 r / min, and stir for 15 minutes to form an oil phase.

[0063] S4: Slowly add the oil phase into the water phase and emulsify under stirring at 300 r / min for 15 minutes to form an emulsion.

[0064] S5: Cool the emulsion to 40°C, add the anti-dandruff agent and anti-shedding agent under stirring at 150 r / min, and stir for 15 minutes to disperse evenly.

[0065] S6: Add essence and stir for 8 minutes, and adjust the color to obtain the anti-dandruff shampoo.

[0066] Example 2

[0067] Raw material preparation

[0068] Surfactants: 10g sodium laureth sulfate (50%), 3g sodium lauroyl sarcosinate (15%), 5g cocamidopropyl betaine (25%).

[0069] Anti-dandruff agent: ketoconazole 3g, salicylic acid 2g.

[0070] Anti-hair loss agent: 3.5g of saw palmetto extract (35%), 3g of ginseng extract (30%), 2.5g of Polygonum multiflorum extract encapsulated by nanoliposomes (25%). In the preparation of the Polygonum multiflorum extract encapsulated by nanoliposomes, 0.8g of Polygonum multiflorum extract, 2g of phospholipids, and 0.5g of cholesterol are used. Other conditions are the same as in Example 1.

[0071] Moisturizer: Sodium hyaluronate 2g (20%), glycerin 5g (50%), panthenol 2g (20%).

[0072] Conditioning agent: Polyquaternium-10 1.5g (30%), guar hydroxypropyltrimonium chloride 2g (40%), hydrolyzed keratin 1g (20%).

[0073] Thickener: Carbomer 1.5g.

[0074] Preservatives: phenoxyethanol 0.25g (50%), methylisothiazolinone 0.15g (30%), sodium benzoate 0.1g (20%).

[0075] Flavor 0.15g.

[0076] Water 62.35g.

[0077] Preparation process

[0078] The steps are the same as those in Example 1, except that the water phase is heated to 42° C. during preparation of S2, the stirring speed of the oil phase is 180 r / min during preparation of S3, the stirring speed of the emulsification is 280 r / min during S4, the stirring speed of the active ingredient addition is 120 r / min during S5, and the stirring speed of the fragrance adjustment is 6 min.

[0079] Example 3

[0080] Raw material preparation

[0081] Surfactants: Sodium laureth sulfate 13g (52%), sodium lauroyl sarcosinate 3g (12%), cocamidopropyl betaine 5g (20%).

[0082] Anti-dandruff agent: piroctone olamine salt 5g, ketoconazole 1g.

[0083] Anti-hair loss agent: 4.5g of saw palmetto extract (45%), 3g of ginseng extract (30%), 1.5g of Polygonum multiflorum extract encapsulated by nanoliposomes (15%). In the preparation of the Polygonum multiflorum extract encapsulated by nanoliposomes, 0.5g of Polygonum multiflorum extract, 1.5g of phospholipids, and 0.3g of cholesterol are used. Other conditions are the same as in Example 1.

[0084] Moisturizer: Sodium hyaluronate 4g (26.7%), glycerin 6g (40%), panthenol 2g (13.3%).

[0085] Conditioning agent: Polyquaternium-10 1.8g (36%), guar hydroxypropyltrimonium chloride 2g (40%), hydrolyzed keratin 0.7g (14%).

[0086] Thickener: Hydroxyethyl cellulose 1.2g.

[0087] Preservatives: phenoxyethanol 0.35g (70%), methylisothiazolinone 0.1g (20%), sodium benzoate 0.05g (10%).

[0088] 0.25g flavor.

[0089] 60.1g of water.

[0090] Preparation process

[0091] The steps are the same as those in Example 1, except that the water phase is heated to 48° C. during preparation of S2, the stirring speed of the oil phase is 220 r / min during preparation of S3, the stirring speed of the emulsification is 320 r / min during S4, the stirring speed of the active ingredient addition is 180 r / min during S5, and the stirring speed of the fragrance adjustment is 7 min.

[0092] Comparative Example 1

[0093] Raw material preparation

[0094] Surfactants: 15g sodium laureth sulfate (60%), 3g sodium lauroyl sarcosinate (12%), 4g cocamidopropyl betaine (16%).

[0095] Anti-dandruff agent: piroctone olamine salt 3g, salicylic acid 1g.

[0096] Anti-hair loss agent: 2g saw palmetto extract, 1.5g ginseng extract, 1.5g common Polygonum multiflorum extract (not encapsulated by nanoliposomes).

[0097] Moisturizer: 8g glycerin (53.3%), 4g panthenol (26.7%).

[0098] Conditioning agents: Polyquaternium-10 1.5g (37.5%), guar hydroxypropyltrimonium chloride 1.5g (37.5%), hydrolyzed keratin 0.5g (12.5%).

[0099] Thickener: Sodium chloride 1.5g.

[0100] Preservatives: phenoxyethanol 0.2g (50%), methylisothiazolinone 0.1g (25%), sodium benzoate 0.1g (25%).

[0101] 0.1g flavor.

[0102] Water 61.7g.

[0103] Preparation process

[0104] The steps are the same as those in Example 1, but the preparation operation of nanoliposome-encapsulated Polygonum multiflorum extract is not performed, and ordinary Polygonum multiflorum extract is directly used, and ultrasound-assisted emulsification (S4) and pre-dispersion treatment (S5) are not used in each step.

[0105] 1. Anti-loss effect test:

[0106] 200 volunteers with hair loss symptoms were selected and randomly divided into 4 groups. The anti-hair loss shampoo prepared in Examples 1-3 and Comparative Example 1 was used once every two days. After three months of use, the anti-hair loss effect was observed. The results are shown in Table 1.

[0107] Table 1

[0108] Group Average hair loss reduction (hair / day) Increase in local hair density (roots / day) Example 1 40-50 10-15 Example 2 35-45 8-12 Example 3 40-50 10-15 Comparative Example 1 20-30 3-5

[0109] As can be seen from Table 1, the volunteers in the embodiment had significantly less hair loss, their hair density increased, and the newly grown hair was thicker and healthier, their hair follicles were in good condition, and their hair growth cycle tended to be normal, while the newly grown hair in the control group was relatively thin and soft, and the health of the hair follicles was not significantly improved.

[0110] 2. Anti-dandruff, moisturizing and conditioning effect test:

[0111] 40 volunteers with symptoms such as dandruff, itching, and dry hair were randomly selected and divided into 4 groups. They were divided into 4 groups and used the backup anti-hair loss shampoo prepared in Examples 1-3 and Comparative Example 1. After two weeks of use, the anti-dandruff, moisturizing, and conditioning effects were tested. The results are shown in Table 2.

[0112] Group Dandruff reduction (%) Increase in hair moisture content (%) Combing resistance reduction (%) Example 1 80-90 20-30 40-50 Example 2 75-85 15-25 35-45 Example 3 80-90 20-30 40-50 Comparative Example 1 50-60 10-15 20-30

[0113] As can be seen from Table 2, the volunteers who used the embodiment had significantly less dandruff, and the symptoms of scalp itching were significantly alleviated. After continuous use for 1 month, the scalp remained basically clean and no dandruff was produced. However, the volunteers who used Comparative Example 1 had slight scalp itching, and after continuous use for 1 month, a small amount of dandruff still appeared occasionally. The volunteers who used the embodiment maintained a good moisture content in their hair, and the smoothness of their hair was significantly improved after use, the resistance during combing was reduced, the glossiness of their hair was increased, and it was not easy to break or split, and the hair quality was effectively improved. However, the improvement effect of the smoothness and glossiness of the hair of the volunteers who used Comparative Example 1 was relatively unobvious, and after using it for a period of time, problems such as dry hair and split ends still occurred.

[0114] In general, the anti-dandruff shampoos of Examples 1-3 show significantly better effects than those of the comparative examples in terms of anti-dandruff, anti-dandruff, moisturizing and conditioning, which fully demonstrates the effectiveness and superiority of the reasonable proportions of the raw materials, the nanoliposome encapsulation technology and the special preparation process in the present invention, and can provide consumers with better quality hair care products.

[0115] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. An anti-dandruff shampoo, characterized in that: Made from the following raw materials in weight percentage: 3-10% of an anti-hair loss agent, wherein the anti-hair loss agent is a mixture of saw palmetto extract, ginseng extract and Polygonum multiflorum extract encapsulated by nanoliposomes in a weight ratio of 2-4:1-3:1-2. The preparation method of the Polygonum multiflorum extract encapsulated by nanoliposomes is as follows: the Polygonum multiflorum extract is mixed with phospholipids and cholesterol in a weight ratio of 1:2-3:0.5-1, an appropriate amount of organic solvent is added to dissolve, the organic solvent is removed by rotary evaporation under reduced pressure at 40-60° C. to form a lipid film, and then a phosphate buffer solution with a pH value of 6-7 is added, and the mixture is treated under ultrasonic conditions with a power of 100-300 W and a frequency of 20-40 kHz for 10-30 minutes to obtain the Polygonum multiflorum extract encapsulated by nanoliposomes; 15-30% surfactant, wherein the surfactant is a mixture of sodium laureth sulfate, sodium lauroyl sarcosinate and cocamidopropyl betaine in a weight ratio of 3-5:1-2:1-3; 2-8% of an anti-dandruff agent, wherein the anti-dandruff agent is one or more of piroctone olamine, salicylic acid and ketoconazole; 5-15% moisturizing agent, wherein the moisturizing agent is a mixture of sodium hyaluronate, glycerin and panthenol in a weight ratio of 1-3:2-5:1-2; 2-6% of a conditioning agent, wherein the conditioning agent is a mixture of polyquaternium-10, guar hydroxypropyltrimethylammonium chloride and hydrolyzed keratin in a weight ratio of 1-2:1-3:1-2; 0.5-2% thickener, wherein the thickener is one or more of sodium chloride, carbomer and hydroxyethyl cellulose; 0.1-0.5% preservative, wherein the preservative is one or more of phenoxyethanol, methylisothiazolinone and sodium benzoate; Fragrance 0.1-0.3%; The balance is water.

2. The anti-dandruff shampoo according to claim 1, characterized in that: The mass fraction of the saw palmetto extract in the anti-hair loss agent is 40-50%, the mass fraction of the ginseng extract is 30-40%, and the mass fraction of the Polygonum multiflorum extract encapsulated by nanoliposomes is 20-30%.

3. The anti-dandruff shampoo according to claim 1, characterized in that: The mass fraction of sodium laureth sulfate in the surfactant is 50-60%, the mass fraction of sodium lauroyl sarcosinate is 20-30%, and the mass fraction of cocamidopropyl betaine is 20-30%.

4. The anti-dandruff shampoo according to claim 1, characterized in that: The mass ratio of piroctone olamine salt, salicylic acid and ketoconazole in the anti-dandruff agent is 1-3:1-2:0-1.

5. The anti-dandruff shampoo according to claim 1, characterized in that: The mass fraction of sodium hyaluronate in the moisturizing agent is 20-30%, the mass fraction of glycerol is 40-50%, and the mass fraction of panthenol is 20-30%.

6. The anti-dandruff shampoo according to claim 1, characterized in that: The mass fraction of polyquaternium-10 in the conditioner is 30-40%, the mass fraction of guar gum hydroxypropyltrimethylammonium chloride is 30-40%, and the mass fraction of hydrolyzed keratin is 20-30%.

7. The anti-dandruff shampoo according to claim 1, characterized in that: The mass ratio of sodium chloride, carbomer and hydroxyethyl cellulose in the thickener is 1-2:0-1:0-1.

8. The anti-dandruff shampoo according to claim 1, characterized in that: The mass fraction of phenoxyethanol in the preservative is 50-70%, the mass fraction of methylisothiazolinone is 20-30%, and the mass fraction of sodium benzoate is 10-20%.

9. A method for preparing an anti-dandruff shampoo, characterized in that: The following steps are involved: S1: Raw material preparation Weigh each raw material according to the weight percentage described in claim 1 to ensure that the purity of each raw material meets the relevant standards. The purity of sodium laureth sulfate in the surfactant is not less than 95%, the purity of sodium lauroyl sarcosinate is not less than 90%, and the purity of cocamidopropyl betaine is not less than 90%; the purity of piroctone olamine salt in the anti-dandruff agent is not less than 98%, the purity of salicylic acid is not less than 99%, and the purity of ketoconazole is not less than 95%; the content of effective ingredients of saw palmetto extract in the anti-hair loss agent is not less than 40%, the content of effective ingredients of ginseng extract is not less than 30%, and the content of effective ingredients of Polygonum multiflorum extract in Polygonum multiflorum encapsulated by nanoliposomes is not less than 10%. The content of active ingredients in the moisturizer shall not be less than 20%; the purity of sodium hyaluronate in the moisturizer shall not be less than 90%, the purity of glycerin shall not be less than 95%, and the purity of panthenol shall not be less than 95%; the purity of polyquaternium-10 in the conditioner shall not be less than 90%, the purity of guar hydroxypropyltrimonium chloride shall not be less than 90%, and the purity of hydrolyzed keratin shall not be less than 85%; the purity of sodium chloride in the thickener shall not be less than 99%, the purity of carbomer shall not be less than 95%, and the purity of hydroxyethyl cellulose shall not be less than 90%; the purity of phenoxyethanol in the preservative shall not be less than 99%, the purity of methylisothiazolinone shall not be less than 95%, and the purity of sodium benzoate shall not be less than 99%; S2: Aqueous Phase Preparation Add the weighed water into the reactor, heat to 40-50°C, add the moisturizer, thickener and preservative in sequence under the condition of stirring at a speed of 200-300r / min, and stir for 15-25min until they are completely dissolved to form a water phase; S3: Oil phase preparation Heat the surfactant at 40-50°C until it is completely melted, add the conditioning agent under the condition of stirring at a speed of 150-250r / min, and stir for 10-20min to form an oil phase; S4: Mixing and emulsification Slowly add the oil phase into the water phase, and carry out emulsification reaction at a stirring speed of 250-350r / min for 15-25min to form an emulsion; S5: Adding active ingredients When the emulsion temperature drops to 35-45°C, add the anti-dandruff agent and anti-shedding agent in sequence at a stirring speed of 100-200r / min, and stir for 10-20 minutes to make them evenly dispersed; S6: Perfumery Finally, add the essence and stir for 5-10 minutes to obtain the anti-dandruff shampoo.

10. The preparation method according to claim 9, characterized in that: In the S2 aqueous phase preparation step, water is heated by indirect heating, such as heating by passing hot water or steam through a jacketed reactor to ensure uniform heating and avoid local overheating; In the S3 oil phase preparation step, a constant temperature heating device is used during the heating and melting process of the surfactant to control the temperature fluctuation range within ±1°C to ensure the stability of the surfactant quality; In the S4 mixing and emulsification step, ultrasound-assisted emulsification can be used during the emulsification reaction, with an ultrasound frequency of 20-40 kHz and an ultrasound time of 5-10 min to improve the emulsification effect and make the shampoo system more stable; In the step of adding active ingredients in S5, the anti-dandruff agent and the anti-shedding agent are pre-dispersed before being added, that is, the anti-dandruff agent and the anti-shedding agent are respectively mixed with a small amount of water or glycerin to form a uniform dispersion and then added to the emulsion to improve its dispersibility and stability; In the S6 perfume adjustment step, the fragrance is first mixed with an appropriate amount of surfactant before being added to form a fragrance emulsion, which is then added to the system to improve the stability and fragrance retention effect of the fragrance.