Bacteriostatic agent based on chlorinated ether ketone and parachlorometaxylenol

Abstract

The invention belongs to the technical field of disinfectants, and provides a bacteriostatic agent based on chlorinated ether ketone and parachlorometaxylenol, and the bacteriostatic agent is prepared from the following components in parts by mass: 20-40 parts of chlorinated ether ketone, 10-30 parts of parachlorometaxylenol, 3-5 parts of a stabilizer, 3-5 parts of a thickening agent and 4-8 parts of an auxiliary agent. The sterilization characteristics of chlorinated ether ketone and parachlorometaxylenol are creatively combined, the efficient sterilization effect can be achieved, growth and reproduction of various microorganisms can be effectively inhibited, it can be ensured that the bacteriostatic agent is not prone to being influenced by environmental factors and losing activity through the addition of the stabilizer, and the bacteriostatic agent is not prone to being damaged by the environmental factors through the addition of the thickening agent and the auxiliary agent. The viscosity of the bacteriostatic agent can be adjusted, the smell of the bacteriostatic agent can also be adjusted, the acceptability of a user is improved, and the bacteriostatic agent can be widely applied to disinfection and bacteriostasis of clothes and household surfaces.

Description

Technical Field

[0001] The invention relates to the technical field of disinfectants, in particular to a bacteriostatic agent based on chloroetherketone and p-chlorometaxylenol. Background Art

[0002] In daily life and industrial production, antibacterial agents are widely used in food, medical, cosmetics, agriculture and other fields to inhibit the growth and reproduction of microorganisms and ensure the quality and safety of products. At present, most of the antibacterial agents on the market have problems such as poor antibacterial effect, poor stability, and easy to develop drug resistance. Therefore, it is of great practical significance to develop a new type of antibacterial agent that is efficient, stable and low in toxicity. Summary of the invention

[0003] The object of the present invention is to provide a bacteriostatic agent based on chloroetherketone and parachlorometaxylenol to overcome the defects of the prior art.

[0004] In order to achieve the above-mentioned object of the invention, the present invention provides the following technical solutions:

[0005] The present invention provides an antibacterial agent based on chloroetherketone and parachlorometaxylenol, which is prepared according to the following principles:

[0006] 20-40 parts of chloroether ketone, 10-30 parts of p-chlorometaxylenol, 3-5 parts of stabilizer, 3-5 parts of thickener, and 4-8 parts of auxiliary agent.

[0007] Preferably, the stabilizer is one or more of ascorbic acid, butylated hydroxyanisole and butylated hydroxytoluene.

[0008] Preferably, the thickener is one or more of polyvinyl alcohol, sodium polyacrylate and polyethylene glycol.

[0009] Preferably, the auxiliary agent is one or more of ethanol, propylene glycol and glycerol.

[0010] The present invention also provides a method for preparing an antibacterial agent based on chloroetherketone and para-chlorometaxylenol, comprising the following steps:

[0011] (1) mixing the raw materials in proportion, stirring and heating to obtain a mixture;

[0012] (2) placing the mixture in a homogenizer for homogenization to obtain the antibacterial agent.

[0013] Preferably, the heating temperature in step (1) is 45-60°C;

[0014] The heating time is 5 to 15 minutes.

[0015] Preferably, the temperature of the homogenization treatment in step (2) is 45-60°C;

[0016] The homogenization time is 3 to 8 minutes;

[0017] The pressure of the homogenization treatment is 20-30 MPa;

[0018] The shear rate of the homogenization process is 2000-3000 rpm.

[0019] Beneficial effects:

[0020] The present invention provides an antibacterial agent based on chloroether ketone and para-chlorometaxylenol, which creatively combines the bactericidal properties of chloroether ketone and para-chlorometaxylenol, can achieve a high-efficiency bactericidal effect, and can effectively inhibit the growth and reproduction of various microorganisms. The addition of a stabilizer can ensure that the antibacterial agent is not easily affected by environmental factors and loses its activity. The addition of a thickener and an auxiliary agent can adjust the viscosity of the antibacterial agent and the odor of the antibacterial agent, thereby improving user acceptance. The antibacterial agent can be widely used for disinfection and bacteriostasis of clothing and household surfaces. DETAILED DESCRIPTION

[0021] The present invention provides an antibacterial agent based on chloroetherketone and parachlorometaxylenol, which is prepared according to the following principles:

[0022] 20-40 parts of chloroether ketone, 10-30 parts of p-chlorometaxylenol, 3-5 parts of stabilizer, 3-5 parts of thickener, and 4-8 parts of auxiliary agent.

[0023] In the present invention, the mass fraction of the chloroetherketone is preferably 22 to 38 parts, more preferably 24 to 36 parts, and even more preferably 26 to 34 parts.

[0024] In the present invention, the mass fraction of the p-chlorometaxylenol is preferably 12 to 28 parts, more preferably 14 to 26 parts, and even more preferably 16 to 24 parts.

[0025] In the present invention, the weight percentage of the stabilizer is preferably 3.2 to 4.8 parts, more preferably 3.4 to 4.6 parts, and even more preferably 3.6 to 4.4 parts.

[0026] In the present invention, the mass fraction of the thickener is preferably 3.2 to 4.8 parts, more preferably 3.4 to 4.6 parts, and even more preferably 3.6 to 4.4 parts.

[0027] In the present invention, the weight percentage of the auxiliary agent is preferably 4.5 to 7.5 parts, more preferably 5 to 7 parts, and even more preferably 5.5 to 6.5 parts.

[0028] In the present invention, the stabilizer is preferably one or more of ascorbic acid, butylated hydroxyanisole and butylated hydroxytoluene.

[0029] In the present invention, the thickener is preferably one or more of polyvinyl alcohol, sodium polyacrylate and polyethylene glycol.

[0030] In the present invention, the auxiliary agent is preferably one or more of ethanol, propylene glycol and glycerol.

[0031] The present invention also provides a method for preparing an antibacterial agent based on chloroetherketone and para-chlorometaxylenol, comprising the following steps:

[0032] (1) mixing the raw materials in proportion, stirring and heating to obtain a mixture;

[0033] (2) placing the mixture in a homogenizer for homogenization to obtain the antibacterial agent.

[0034] In the present invention, the heating temperature in step (1) is preferably 45 to 60°C, more preferably 48 to 57°C, and even more preferably 50 to 55°C.

[0035] In the present invention, the heating time is preferably 5 to 15 minutes, more preferably 7 to 13 minutes, and even more preferably 9 to 11 minutes.

[0036] In the present invention, the mixing and stirring rate is preferably 150 to 300 rpm, more preferably 170 to 280 rpm, and even more preferably 200 to 250 rpm.

[0037] In the present invention, the temperature of the homogenization treatment in step (2) is preferably 45 to 60°C, more preferably 48 to 57°C, and even more preferably 50 to 55°C.

[0038] In the present invention, the homogenization treatment time is preferably 3 to 8 minutes, more preferably 4 to 7 minutes, and even more preferably 5 to 6 minutes.

[0039] In the present invention, the pressure of the homogenization treatment is 20 to 30 MPa, more preferably 22 to 28 MPa, and even more preferably 24 to 26 MPa.

[0040] In the present invention, the shear rate of the homogenization treatment is 2000-3000 rpm, more preferably 2200-2800 rpm, and even more preferably 2400-2600 rpm.

[0041] In the present invention, after the homogenization treatment is completed, the mixture needs to be cooled to room temperature to obtain the antibacterial agent.

[0042] The technical solutions provided by the present invention are described in detail below in conjunction with the embodiments, but they should not be construed as limiting the protection scope of the present invention.

[0043] Example 1

[0044] The following parts by mass are weighed: 30 parts of chloroether ketone, 20 parts of para-chloro-metaxylenol, 4 parts of butylated hydroxyanisole, 4 parts of polyvinyl alcohol, and 6 parts of glycerol, and the raw materials are mixed at a stirring rate of 200 rpm, and heated at 50°C for 10 minutes to obtain a mixture; then the mixture is placed in a homogenizer and homogenized for 5 minutes at a shear rate of 2500 rpm, a pressure of 25 MPa, and a temperature of 50°C, and then cooled to room temperature to obtain the antibacterial agent.

[0045] Example 2

[0046] The following parts by mass are weighed: 28 parts of chloroether ketone, 18 parts of para-chloro-metaxylenol, 4 parts of butylated hydroxyanisole, 3 parts of polyvinyl alcohol, and 5 parts of glycerol. The raw materials are mixed at a stirring rate of 200 rpm, and heated at 50°C for 10 min to obtain a mixture; then the mixture is placed in a homogenizer and homogenized for 5 min at a shear rate of 2500 rpm, a pressure of 25 MPa, and a temperature of 50°C, and then cooled to room temperature to obtain the antibacterial agent.

[0047] Example 3

[0048] The following parts by mass are weighed: 28 parts of chloroether ketone, 18 parts of para-chloro-metaxylenol, 4 parts of ascorbic acid, 4 parts of polyvinyl alcohol, and 6 parts of glycerol. The raw materials are mixed at a stirring rate of 250 rpm, and heated at 55° C. for 10 min to obtain a mixture; the mixture is then placed in a homogenizer and homogenized for 6 min at a shear rate of 2500 rpm, a pressure of 25 MPa, and a temperature of 55° C., and then cooled to room temperature to obtain the antibacterial agent.

[0049] Example 4

[0050] The following parts by mass are weighed: 20 parts of chloroether ketone, 10 parts of para-chloro-metaxylenol, 3 parts of ascorbic acid, 3 parts of polyethylene glycol, and 4 parts of ethanol, and the raw materials are mixed at a stirring rate of 150 rpm, and heated at 45° C. for 5 min to obtain a mixture; then the mixture is placed in a homogenizer and homogenized for 3 min at a shear rate of 2000 rpm, a pressure of 20 MPa, and a temperature of 45° C., and then cooled to room temperature to obtain the antibacterial agent.

[0051] Example 5

[0052] The following parts by mass are weighed: 40 parts of chloroether ketone, 30 parts of parachlorometaxylenol, 5 parts of ascorbic acid, 5 parts of polyethylene glycol, and 8 parts of glycerol, and the raw materials are mixed at a stirring rate of 300 rpm, and heated at 60°C for 15 minutes to obtain a mixture; then the mixture is placed in a homogenizer and homogenized for 8 minutes at a shear rate of 3000 rpm, a pressure of 30 MPa, and a temperature of 60°C, and then cooled to room temperature to obtain the antibacterial agent.

[0053] It can be seen from the above embodiments that the present invention provides an antibacterial agent based on chloroether ketone and para-chlorometaxylenol, which creatively combines the bactericidal properties of chloroether ketone and para-chlorometaxylenol, can achieve a high-efficiency bactericidal effect, and can effectively inhibit the growth and reproduction of various microorganisms. By adding a stabilizer, it can be ensured that the antibacterial agent is not easily affected by environmental factors and loses its activity. The addition of a thickener and an auxiliary agent can adjust the viscosity of the antibacterial agent, and can also adjust the odor of the antibacterial agent, thereby improving user acceptance. The antibacterial agent can be widely used for disinfection and antibacterial of clothing and household surfaces.

[0054] The above is only a preferred embodiment of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principle of the present invention. These improvements and modifications should also be regarded as the scope of protection of the present invention.

Claims

1. A bacteriostatic agent based on chloroetherketone and parachlorometaxylenol, characterized in that: The preparation is obtained by the principle of the following mass fractions: 20-40 parts of chloroether ketone, 10-30 parts of p-chlorometaxylenol, 3-5 parts of stabilizer, 3-5 parts of thickener, and 4-8 parts of auxiliary agent.

2. The antibacterial agent based on chloroetherketone and parachlorometaxylenol according to claim 1, characterized in that: The stabilizer is one or more of ascorbic acid, butylated hydroxyanisole and butylated hydroxytoluene.

3. The antibacterial agent based on chloroetherketone and para-chloro-meta-xylenol according to claim 1, characterized in that: The thickener is one or more of polyvinyl alcohol, sodium polyacrylate and polyethylene glycol.

4. A bacteriostatic agent based on chloroetherketone and parachlorometaxylenol according to claim 1, characterized in that: The auxiliary agent is one or more of ethanol, propylene glycol and glycerol.

5. A method for preparing an antibacterial agent based on chloroetherketone and para-chloro-metaxylenol according to any one of claims 1 to 4, characterized in that: The following steps are involved: (1) mixing the raw materials in proportion, stirring and heating to obtain a mixture; (2) placing the mixture in a homogenizer for homogenization to obtain the antibacterial agent.

6. The preparation method according to claim 5, characterized in that: The heating temperature in step (1) is 45-60° C.; The heating time is 5 to 15 minutes.

7. The preparation method according to claim 5, characterized in that: The temperature of the homogenization treatment in step (2) is 45-60°C; The homogenization time is 3 to 8 minutes; The pressure of the homogenization treatment is 20-30 MPa; The shear rate of the homogenization process is 2000-3000 rpm.