A soothing, long-lasting, sun-protective isolation cream and its preparation method

Abstract

The present invention relates to the field of skin cosmetics, and in particular to a soothing, long-lasting, sun-protective isolation cream and its preparation method. The isolation cream's raw materials include butylene glycol, isododecane, polydimethylsiloxane, ethylhexyl salicylate, phenylbenzimidazole sulfonic acid, butyloctanol salicylate, diisopropyl sebacate, diisopropyl adipate, vinyl polydimethylsiloxane / polymethylsilane silsesquioxane crosspolymer, ethylhexyl triazone, p-hydroxyacetophenone, disteardimonium hectorite, aluminum hydroxide, Piper mesenteriae leaf / root / stem extract, Gentiana scabra extract, and water. The isolation cream prepared by the present invention has good soothing, long-lasting, and sun-protective effects, as well as excellent free radical resistance and moisturizing effects. It is easy to apply and can improve skin gloss to a certain extent.

Description

Technical Field

[0001] The present invention relates to the field of skin cosmetics, and in particular to a soothing, long-lasting, sun-proof isolation cream and a preparation method thereof. Background Art

[0002] Primer is a cosmetic product used to create a protective barrier between makeup and skin, shielding it from harmful external agents. Its key ingredients, including sunscreen, antioxidants, and nourishing active ingredients, shield against UV rays, pollutants, and radiation while providing hydration and tone.

[0003] Invention patent CN114617799B discloses a water-soluble primer for nourishing, brightening, and improving makeup stickiness, and its preparation method. The primer uses ingredients, by weight, including: 50-70 parts water, 1-5 parts inorganic salt, 22-50 parts humectant, 3.5-65 parts emollient, and 0.6-30 parts skin conditioner. The humectant is a combination of gluconolactone, a polyol, and sodium hyaluronate. This patent requires a large amount of synthetic humectant to maintain effective moisturizing effects; using a small amount of this humectant results in poor moisturizing effects.

[0004] Invention patent CN113520935B discloses a colorful multifunctional primer and its preparation method. The primer primarily comprises: 5-10 parts chamomile extract, 5-10 parts licorice extract, 5-10 parts grape seed oil, 5-10 parts arbutin, 1-5 parts hyaluronic acid, 1-5 parts vitamin E, 1-5 parts ginsenoside, 10-15 parts shea butter, 5-10 parts surface-modified zinc oxide / attapulgite-based Maya blue composite pigment, and 20-30 parts distilled water. Although the primer utilizes a large amount of plant extracts, the extraction process is not optimized, and no long-lasting stabilizing ingredients are added. Consequently, the resulting primer has limited anti-inflammatory, soothing, and long-lasting effects.

[0005] Given the wide variety of primers on the market, but the varying complex functions, a technical challenge currently needs to be addressed: providing a primer that offers excellent soothing, long-lasting, sun-protective properties while maintaining good moisturizing and anti-oxidation properties while using a low level of moisturizing ingredients. Summary of the Invention

[0006] In response to the above technical problems, the present invention provides a soothing, long-lasting, sun-protective isolation cream and a preparation method thereof.

[0007] The invention provides a soothing, long-lasting and sun-protective isolation cream, which is characterized by comprising polyol, emollient, sunscreen, suspending agent, stabilizer, oil-control agent, preservative and water.

[0008] Further, the polyol includes butanediol.

[0009] Further, the emollient includes isododecane, dimethicone, diisopropyl sebacate, and diisopropyl adipate.

[0010] Further, the sunscreen includes ethylhexyl salicylate, phenylbenzimidazole sulfonic acid, butyloctanol salicylate and ethylhexyl triazone.

[0011] Furthermore, the suspending agent includes disteardimethylammonium hectorite.

[0012] Further, the stabilizer includes vinyl dimethicone / polymethylsilane silsesquioxane crosspolymer.

[0013] Further, the preservative includes p-hydroxyacetophenone.

[0014] Furthermore, the oil control agent includes aluminum hydroxide.

[0015] The soothing, long-lasting, and sun-protective isolation cream provided by the present invention comprises, in percentage by mass, 12-15% butylene glycol, 0.5-5% isododecane, 1-4% polydimethylsiloxane, 0.5-2.5% ethylhexyl salicylate, 0.5-1% phenylbenzimidazole sulfonic acid, 0.5-1% butyloctanol salicylate, 1-4% diisopropyl sebacate, 1-4% diisopropyl adipate, 4-8% vinyl polydimethylsiloxane / polymethylsilane silsesquioxane crosspolymer, 0.5-1% ethylhexyl triazone, 0.001-0.2% p-hydroxyacetophenone, 2-6% disteardimonium hectorite, 0.5-2% aluminum hydroxide, and the balance water.

[0016] Furthermore, the amount of butanediol may be 12.5%, 13%, 13.5%, 14%, 14.5% or 15%.

[0017] Furthermore, the amount of isododecane can be 0.5%, 1%, 2%, 3%, 3.5%, 4%, 4.5%, or 5%.

[0018] Furthermore, the amount of polydimethylsiloxane can be 1%, 2%, 2.5%, 3%, 3.5%, or 4%.

[0019] Furthermore, the amount of ethylhexyl salicylate can be 1%, 1.5%, 1.8%, 2%, 2.2%, or 2.5%.

[0020] Furthermore, the dosage of phenylbenzimidazole sulfonic acid can also be 0.6%, 0.8%, or 0.9%.

[0021] Furthermore, the dosage of butyl octanol salicylate can also be 0.6%, 0.8%, or 0.9%.

[0022] Furthermore, the amount of diisopropyl sebacate can also be 1%, 2%, 2.5%, 3%, 3.5%, or 4%.

[0023] Furthermore, the amount of diisopropyl adipate can also be 1%, 2%, 2.5%, 3%, 3.5%, or 4%.

[0024] Furthermore, the amount of vinyl polydimethylsiloxane / polymethylsilane silsesquioxane crosslinked polymer can also be 5%, 6%, 6.5%, 7%, 7.5%, or 8%.

[0025] Furthermore, the dosage of ethylhexyl triazone can also be 0.6%, 0.8%, or 0.9%.

[0026] Furthermore, the amount of p-hydroxyacetophenone can also be 0.002%, 0.005%, 0.008%, 0.01%, 0.05%, 0.08%, 0.1%, or 0.2%.

[0027] Furthermore, the amount of disteardimethylammonium hectorite can also be 2%, 3%, 4%, 4.5%, 5%, 5.5%, or 6%.

[0028] Furthermore, the amount of aluminum hydroxide can also be 0.6%, 0.8%, 1%, 1.2%, 1.5%, or 2%.

[0029] Furthermore, the soothing, long-lasting, sun-protective isolation cream further comprises, by weight percentage, 1-3% of Kava Piper nigrum leaf / root / stem extract and 0.8-2.8% of Gentiana scabra extract.

[0030] Furthermore, the amount of the Piper melongena leaf / root / stem extract can be 1%, 1.5%, 1.8%, 2%, 2.2%, 2.5%, or 3%.

[0031] Furthermore, the dosage of gentian extract can also be 0.8%, 1%, 1.5%, 1.8%, 2%, 2.2%, 2.5%, or 2.8%.

[0032] The present invention provides a method for preparing a Piper methysticum leaf / root / stem extract, comprising the following steps:

[0033] S1: Mix the leaves, roots, and stems of Piper methysticum in a mass ratio of 1:0.5-1:0.2-0.5, grind, and obtain a ground material. Add water 8-40 times the mass of the ground material and boil, then stir at 60-80° C. for 1-3 hours, and cool to obtain a cooled material.

[0034] S2: adding ginger protease and serrapeptase to the cooled material, performing enzymatic hydrolysis at 40-60° C. for 2-6 hours, inactivating the enzymes, and obtaining an enzymatic hydrolyzate; wherein the total amount of ginger protease and serrapeptase added to each gram of the cooled material is 1500-2000 U, and the ratio of ginger protease to serrapeptase is 2-4:1;

[0035] S3: adding anhydrous ethanol to the enzymatic hydrolysate to adjust the ethanol mass concentration to 40-60%, heating to 50-60° C. and stirring to perform extraction for 2-5 hours, filtering, concentrating, and drying to obtain the Piper methysticum leaf / root / stem extract.

[0036] The present invention also provides a method for preparing a gentian extract, comprising the following steps:

[0037] (1) Crush the plant gentian to obtain plant powder, add 50-70% ethanol aqueous solution with a mass concentration of 10-40 times the mass of the powder, heat and stir at 50-65°C for 4-8 hours to obtain material A;

[0038] (2) Material A is concentrated under reduced pressure to 0.25-0.45 times the mass of the plant powder to obtain a concentrate, and a composite extractant of 20-40 times the mass of the concentrate is added, and the mixture is extracted at 40-50° C. for 2-6 hours, and the mixture is allowed to stand for stratification. The organic phase is taken and concentrated under reduced pressure until the extractant component cannot be detected to obtain the gentian extract;

[0039] The composite extractant is composed of an organic phase and an aqueous phase in a mass ratio of 3-5:1; the organic phase is composed of ethyl acetate and cyclohexane in a mass ratio of 1:0.5-0.8, and the aqueous phase is water.

[0040] The present invention also provides a method for preparing the soothing, long-lasting, sun-protective isolation cream, comprising the following steps:

[0041] Step 1: Add disteardimethylammonium hectorite and water into a container, heat to 50-70° C., and stir at 300-3000 rpm for 0.1-3 hours to obtain a mixture 1;

[0042] Step 2: Add butylene glycol, isododecane, polydimethylsiloxane, ethylhexyl salicylate, phenylbenzimidazole sulfonic acid, butyloctanol salicylate, diisopropyl sebacate, diisopropyl adipate, vinyl polydimethylsiloxane / polymethylsilane silsesquioxane crosspolymer, ethylhexyl triazone, and p-hydroxyacetophenone into a container, heat to 70-85° C., and stir at 50-600 rpm for 0.1-2 hours to obtain a mixture 2;

[0043] Step 3: Add mixture 1 to mixture 2, and stir at 60-400 rpm for 0.1-1 hour; cool, add the remaining raw materials, continue stirring for 0.1-1 hour, let stand for aging, and sterilize to obtain the soothing, long-lasting, sunscreen isolation cream.

[0044] The present invention has the following beneficial effects compared with the prior art:

[0045] The invention adopts ethylhexyl salicylate, phenylbenzimidazole sulfonic acid, butyloctanol salicylate and ethylhexyl triazone as sunscreen active ingredients to impart excellent sunscreen effect to the isolation cream; adopts isododecane, polydimethylsiloxane, diisopropyl sebacate and diisopropyl adipate to impart skin moisturizing effect to the isolation cream; adopts suspending agent and stabilizer to make the isolation cream stable, easy to apply and long-lasting; adopts oil-control agent aluminum hydroxide to impart refreshing and oil-absorbing effect to the isolation cream, while improving the application and lasting effect of the isolation cream to a certain extent; adopts Piper methysticum leaf / root / stem extract and Gentiana scabra extract to impart anti-inflammatory and skin-soothing effect to the isolation cream, while further enhancing the skin moisturizing and gloss-improving effects of the isolation cream.

[0046] The present invention utilizes hot water dissolution, combined enzymatic hydrolysis with ginger protease and serrapeptase, and extraction with an aqueous ethanol solution to prepare a Piper methysticum leaf / root / stem extract that exhibits excellent free radical scavenging and skin moisturizing properties. The synergistic combination of ginger protease and serrapeptase, along with the selection of a 2-4:1 ratio and the ethanol solution extraction concentration, significantly impacts the free radical scavenging and moisturizing properties of the Piper methysticum leaf / root / stem extract.

[0047] The gentian extract prepared by the present invention, which is extracted using an ethanol-water solution and a composite extractant, has excellent free radical resistance and moisturizing effects. Furthermore, the selection of the ethanol-water solution concentration and the selection and proportion of the organic phase of the composite extractant significantly influence the efficacy of the gentian extract.

[0048] The isolation cream prepared by the invention has good sun protection, moisturizing, smearing and skin gloss improvement effects.

[0049] The preparation method of the present invention is simple, the isolation cream has excellent effect, and has good application prospects. DETAILED DESCRIPTION

[0050] The present invention will be described below in conjunction with specific embodiments, and the various effects of the present invention will be more clearly presented. It should be understood by those skilled in the art that these specific embodiments are intended to illustrate the present invention, not to limit the present invention. Unless otherwise specified, the raw materials used in the specific embodiments of the present invention can be obtained through common commercial channels.

[0051] 1. Preparation of plant extract raw materials

[0052] 1. Preparation of Kava Leaf / Root / Stem Extract

[0053] Kava Kava Leaf / Root / Stem Extract I:

[0054] The preparation method is as follows:

[0055] S1: The leaves, roots, and stems of Piper methysticum were mixed in a mass ratio of 1:0.8:0.3, and ground to obtain a ground material. Water 30 times the mass of the ground material was added and boiled, followed by heating at 65° C. and stirring at 60 rpm for 2 hours, and cooling to room temperature to obtain a cooled material.

[0056] S2: adding gingerase and serrapeptase to the cooled material, performing enzymatic hydrolysis at 50°C for 4.5 hours (stirring at 60 rpm), inactivating the enzymes, and obtaining an enzymatic hydrolyzate; wherein the total amount of gingerase and serrapeptase added to each gram of the cooled material is 1800 U, and the ratio of gingerase to serrapeptase is 3:1 (i.e., the amounts of gingerase and serrapeptase added to each gram of the cooled material are 1350 U and 450 U, respectively);

[0057] S3: Anhydrous ethanol was added to the hydrolysate to adjust the ethanol concentration to 52%, and the mixture was heated at 57°C and stirred at 70 rpm for 4.2 hours. The mixture was filtered through a 0.2 μm pore size filter membrane, and the mixture was concentrated under reduced pressure at 55°C to a water content of 27.6%. The mixture was freeze-dried at -42°C to a water content of 3.16% to obtain the Piper mesenteriae leaf / root / stem extract.

[0058] Kava Kava Leaf / Root / Stem Extract II:

[0059] The preparation method is as follows:

[0060] S1: The leaves, roots, and stems of Piper methysticum were mixed in a mass ratio of 1:1:0.2, and ground to obtain a ground material. Water 32 times the mass of the ground material was added and boiled, followed by heating at 62° C. and stirring at 60 rpm for 2.2 hours, and then cooled to room temperature to obtain a cooled material.

[0061] S2: adding zingiberenase and serrapeptase to the cooled material, performing enzymatic hydrolysis at 52°C for 4.8 hours (stirring at 60 rpm), inactivating the enzymes, and obtaining an enzymatic hydrolyzate; wherein the total amount of zingiberenase and serrapeptase added to each gram of the cooled material is 1820 U, and the ratio of zingiberenase to serrapeptase is 2.5:1 (i.e., the amounts of zingiberenase and serrapeptase added to each gram of the cooled material are 1300 U and 520 U, respectively);

[0062] S3: Anhydrous ethanol was added to the hydrolysate to adjust the ethanol concentration to 45%, and the extract was heated at 55°C and stirred at 70 rpm for 3.9 hours. The extract was filtered through a 0.2 μm pore size filter membrane, and the extract was concentrated under reduced pressure at 55°C to a water content of 25.4%. The extract was freeze-dried at -40°C to a water content of 3.09% to obtain the Piper methysticum leaf / root / stem extract.

[0063] Kava Kava Leaf / Root / Stem Extract III:

[0064] This product differs from Kava Leaf / Root / Stem Extract I in that: Step S2: Zingiber officinale is added to the cooled material, and enzymatic hydrolysis is carried out at 50°C for 4.5 hours (stirring at 60 rpm), followed by enzyme inactivation to obtain a hydrolyzate. The amount of Zingiber officinale added is 1800 U per gram of cooled material. All other aspects are the same as those of Kava Leaf / Root / Stem Extract I.

[0065] Kava Kava Leaf / Root / Stem Extract IV:

[0066] This product differs from Kava Leaf / Root / Stem Extract I in that: Step S2: Serrapeptase is added to the cooled material, and enzymatic hydrolysis is carried out at 50°C for 4.5 hours (stirring at 60 rpm), followed by enzyme inactivation to obtain a hydrolyzate. The amount of serrapeptase added is 1800 U per gram of cooled material. All other aspects are the same as Kava Leaf / Root / Stem Extract I.

[0067] Kava Kava Leaf / Root / Stem Extract V:

[0068] The difference from Kava leaf / root / stem extract I is that in step S2, the total amount of gingerase and serrapeptase added to each gram of the cooled material is 1800 U, and the ratio of gingerase to serrapeptase is 0.8:1 (i.e., the amounts of gingerase and serrapeptase added to each gram of the cooled material are 800 U and 1000 U, respectively). Otherwise, the same as Kava leaf / root / stem extract I.

[0069] Kava Kava Leaf / Root / Stem Extract VI:

[0070] The difference from Kava leaf / root / stem extract I is that in step S2, the total amount of gingerase and serrapeptase added to each gram of the cooled material is 1800 U, and the ratio of gingerase to serrapeptase is 8:1 (i.e., the amounts of gingerase and serrapeptase added to each gram of the cooled material are 1600 U and 200 U, respectively). Otherwise, the same as Kava leaf / root / stem extract I.

[0071] Kava Kava Leaf / Root / Stem Extract VII:

[0072] The difference from Kava leaf / root / stem extract I is that: Step S2: anhydrous ethanol is added to the enzymatic hydrolyzate to adjust the ethanol concentration to 20%. All other aspects are the same as Kava leaf / root / stem extract I.

[0073] Kava Kava Leaf / Root / Stem Extract VIII:

[0074] The difference from Kava leaf / root / stem extract I is that in step S2, anhydrous ethanol is added to the enzymatic hydrolyzate to adjust the ethanol concentration to 85%. All other aspects are the same as Kava leaf / root / stem extract I.

[0075] 2. Preparation of Gentiana Extract

[0076] Gentiana Extract I:

[0077] The preparation method is as follows:

[0078] (1) Crush the gentian root to obtain plant powder, add 58% ethanol aqueous solution with a mass concentration of 27 times the mass of the powder, heat at 60°C and stir at 70 rpm for 6.2 hours to obtain material A;

[0079] (2) Material A was concentrated under reduced pressure at 57°C to a mass of 0.32 times the mass of the plant powder to obtain a concentrate, and a composite extractant 32 times the mass of the concentrate was added, extracted at 48°C and stirred at 50 rpm for 4.7 hours, allowed to stand for 1 hour, and the organic phase was taken and concentrated under reduced pressure at 48°C until the extractant component could not be detected to obtain the gentian extract;

[0080] The composite extractant is composed of an organic phase and an aqueous phase in a mass ratio of 4.5:1; the organic phase is composed of ethyl acetate and cyclohexane in a mass ratio of 1:0.75, and the aqueous phase is water.

[0081] Gentiana Extract II:

[0082] The preparation method is as follows:

[0083] (1) Crush the gentian root to obtain plant powder, add 65% ethanol aqueous solution with a mass concentration of 30 times the mass of the powder, heat at 60°C and stir at 70 rpm for 6.5 hours to obtain material A;

[0084] (2) Material A was concentrated under reduced pressure at 57°C to a mass of 0.34 times that of the plant powder to obtain a concentrate, and a composite extractant 35 times the mass of the concentrate was added, extracted at 48°C and stirred at 50 rpm for 5 hours, allowed to stand for 1 hour, and the organic phase was taken and concentrated under reduced pressure at 48°C until the extractant component could not be detected to obtain the gentian extract;

[0085] The composite extractant is composed of an organic phase and an aqueous phase in a mass ratio of 3:1; the organic phase is composed of ethyl acetate and cyclohexane in a mass ratio of 1:0.5, and the aqueous phase is water.

[0086] Gentiana Extract III:

[0087] The difference from Gentiana Extract I is that in step (1), anhydrous ethanol is added to the enzymatic hydrolysate to adjust the ethanol concentration to 30%. Other steps are the same as Gentiana Extract I.

[0088] Gentiana Extract IV:

[0089] The difference from Gentiana Extract I is that in step (1), anhydrous ethanol is added to the enzymatic hydrolysate to adjust the ethanol concentration to 87%. Other steps are the same as Gentiana Extract I.

[0090] Gentiana Extract V:

[0091] The difference from Gentiana Extract I is that in step (2), the organic phase is ethyl acetate. Other steps are the same as Gentiana Extract I.

[0092] Gentiana Extract VI:

[0093] The difference from Gentiana Extract I is that in step (2), the organic phase is cyclohexane. Other steps are the same as Gentiana Extract I.

[0094] Gentiana Extract VII:

[0095] The difference from Gentiana Extract I is that in step (2), the organic phase is chloroform. Other steps are the same as Gentiana Extract I.

[0096] Gentiana Extract VIII:

[0097] The difference from Gentiana Extract I is that in step (2), the organic phase is composed of ethyl acetate and cyclohexane in a mass ratio of 1:0.1. Other components are the same as Gentiana Extract I.

[0098] Gentiana Extract IX:

[0099] The difference from Gentiana Extract I is that in step (2), the organic phase is composed of ethyl acetate and cyclohexane in a mass ratio of 1:1.5. Other components are the same as Gentiana Extract I.

[0100] 2. Extract Effect Verification

[0101] DPPH resistance test:

[0102] Mix DPPH with 65% ethanol to prepare a DPPH solution with a DPPH concentration of 0.12 mg / mL. Take the above-mentioned Kava Piper methysticum leaf / root / stem extract or Gentiana scabra extract, dilute it with 65% ethanol to a mass concentration of 0.5%, and obtain an extract dilution. Mix 0.5 mL of the dilution with 2.5 mL of DPPH solution, and store it in the dark for 30 minutes to obtain an experimental group sample. Mix 0.5 mL of 65% ethanol with 2.5 mL of DPPH solution, and store it in the dark for 30 minutes to obtain a blank group sample. Use a UV-visible spectrophotometer to measure the absorbance A of each group. 517 , parallel measurement three times to take the average value. Calculate DPPH resistance rate % = (blank group A 517 Value-Experimental Group A 517 ) / Blank group A 517 ×100%.

[0103] Moisturizing ability test:

[0104] Volunteers aged 30-50 years with no history of alcohol allergy were randomly divided into 17 groups, each consisting of 3 men and 3 women. A 3cm x 3cm area of ​​skin on the volunteers' wrists was used as a test area. A diluted solution of the extract (diluted with 70% alcohol to a 5% mass concentration of the extract) was evenly applied to the test area, using a dosage of 0.32g. Skin moisture content data for the test area was collected before, 3 hours after, and 10 hours after sample application. The specific collection procedure was to use a skin moisture meter to measure moisture content, averaging the data from 5 points within the test area. The test environment was 24°C and 57% humidity. The increase in skin moisture content (Q) was then calculated after 3 and 10 hours of sample application compared to the pre-test moisture content. This increase Q was calculated as 100% × (skin moisture content after application - skin moisture content before application) / skin moisture content before application.

[0105] The results of the above tests are shown in Table 1.

[0106] Table 1: DPPH resistance and moisturizing ability

[0107]

[0108] According to the test results in Table 1, the extracts from the Piper methysticum leaf / root / stem prepared by the present invention using hot water dissolution, combined enzymatic hydrolysis with ginger protease and serrapeptase, and extraction with aqueous ethanol solution have a good free radical resistance effect and excellent skin moisturizing effect. Furthermore, according to the extract test data, the synergistic combination of ginger protease and serrapeptase, the selection of a ratio of 2-4:1, and the ethanol solution extraction concentration all have a significant impact on the free radical scavenging and moisturizing effects of the Piper methysticum leaf / root / stem extract.

[0109] The test results in Table 1 indicate that the gentian extracts prepared using both ethanol-water extraction and composite extraction agents exhibit excellent free radical protection and moisturizing properties. Furthermore, test data for the extracts indicate that the choice of ethanol-water concentration and the selection and proportion of the composite extractant organic phase significantly influence the efficacy of the gentian extracts.

[0110] 3. Preparation and application test of isolation cream

[0111] 1. Preparation of isolation cream

[0112] Makeup base 1 is prepared as follows:

[0113] The raw material information is as follows: in terms of mass percentage: 14% 1,3-butylene glycol, 3% isododecane, 2% dimethicone, 1% ethylhexyl salicylate, 0.8% phenylbenzimidazole sulfonic acid, 0.8% butyloctanol salicylate, 2% diisopropyl sebacate, 2% diisopropyl adipate, 6% vinyl dimethicone / polymethylsilane silsesquioxane crosspolymer, 0.8% ethylhexyl triazone, 0.05% p-hydroxyacetophenone, 4.8% disteardimonium hectorite, 0.6% aluminum hydroxide, 2% kava leaf / root / stem extract 1 and 1.8% gentiana extract 1 and the balance water.

[0114] Disteardimethylammonium hectorite and water were added to a container, heated to 60° C., and stirred at 1000 rpm for 0.5 hours to obtain a mixture 1;

[0115] 1,3-Butanediol, isododecane, polydimethylsiloxane, ethylhexyl salicylate, phenylbenzimidazole sulfonic acid, butyloctanol salicylate, diisopropyl sebacate, diisopropyl adipate, vinyl polydimethylsiloxane / polymethylsilane silsesquioxane crosspolymer, ethylhexyl triazone, and p-hydroxyacetophenone were added to a container, heated to 82° C., and stirred at 90 rpm for 0.6 hour to obtain a mixture 2;

[0116] Mixture 1 was added to mixture 2, and stirred at 200 rpm for 0.5 hour; the temperature was lowered to 50° C., the remaining raw materials were added, and stirring was continued for 0.4 hour. The mixture was allowed to stand for 2 hours and sterilized to obtain the isolation cream.

[0117] Makeup base 2 is prepared as follows:

[0118] The raw material information is as follows: in terms of mass percentage: 13.5% 1,3-butylene glycol, 3.2% isododecane, 1.8% dimethicone, 1.2% ethylhexyl salicylate, 0.6% phenylbenzimidazole sulfonic acid, 0.7% butyloctanol salicylate, 2.2% diisopropyl sebacate, 2.2% diisopropyl adipate, 6.8% vinyl dimethicone / polymethylsilane silsesquioxane crosspolymer, 0.9% ethylhexyl triazone, 0.05% p-hydroxyacetophenone, 5% disteardimonium hectorite, 0.4% aluminum hydroxide, 1.5% kava leaf / root / stem extract 2 and 2.4% gentiana extract 2 and the balance water.

[0119] Disteardimethylammonium hectorite and water were added to a container, heated to 62° C., and stirred at 1000 rpm for 0.6 hours to obtain a mixture 1;

[0120] 1,3-Butanediol, isododecane, polydimethylsiloxane, ethylhexyl salicylate, phenylbenzimidazole sulfonic acid, butyloctanol salicylate, diisopropyl sebacate, diisopropyl adipate, vinyl polydimethylsiloxane / polymethylsilane silsesquioxane crosspolymer, ethylhexyl triazone, and p-hydroxyacetophenone were added to a container, heated to 84° C., and stirred at 100 rpm for 0.5 hour to obtain a mixture 2;

[0121] Mixture 1 was added to mixture 2, and the mixture was stirred at 150 rpm for 0.7 hours. The mixture was cooled to 52° C., and the remaining raw materials were added, and the mixture was stirred for 0.5 hours. The mixture was allowed to stand for 2.2 hours and sterilized to obtain the isolation cream.

[0122] Makeup base 3 is prepared as follows:

[0123] The raw materials are as follows: by mass percentage: 2% 1,3-Butanediol, 3% Isododecane, 2% Dimethicone, 1% Ethylhexyl Salicylate, 0.8% Phenylbenzimidazole Sulfonic Acid, 0.8% Butyloctanol Salicylate, 2% Diisopropyl Sebacate, 2% Diisopropyl Adipate, 0.5% Vinyl Dimethicone / Polymethylsilsesquioxane Crosspolymer, 0.8% Ethylhexyl Triazone, 0.05% Parahydroxyacetophenone, 0.2% Disteardimonium Hectorite, 0.6% Aluminum Hydroxide, 0.2% Kava Piperita Leaf / Root / Stem Extract 1 and 0.2% Gentiana Lucidum Extract 1, and the balance is water. All other ingredients are the same as those in Makeup Base 1.

[0124] 2. Application test of isolation cream

[0125] Thirty volunteers aged 25-40 with healthy skin were randomly divided into 10 groups, 5 men and 5 women. Each group was tested using the aforementioned primer. One gram of primer was evenly applied to the face once daily for seven consecutive days. The primer was then rated for its sun protection, moisturizing, spreadability, and improved skin radiance. Each test was scored with a maximum of 5 and a minimum of 0. The average score for each group was calculated. See Table 2 for details.

[0126] Table 2: Base Cream Test Results

[0127]

[0128] As shown in Table 2, the isolation cream prepared by the present invention has good sun protection, moisturizing, spreadability, and skin gloss improvement effects. Reducing the amount of raw materials such as butylene glycol, vinyl polydimethylsiloxane / polymethylsilsesquioxane crosspolymer, and disteardimonium hectorite has a certain impact on sun protection, moisturizing, spreadability, and skin gloss improvement, with a particularly significant impact on spreadability.

[0129] Obviously, those skilled in the art may make various changes and modifications to the present invention without departing from the spirit and scope of the present invention. Thus, if such changes and modifications fall within the scope of the claims and their equivalents, the present invention is intended to include such changes and modifications.

Claims

1. A soothing, long-lasting, sun-protective isolation cream, characterized in that: According to mass percentage, it includes: 12-15% butylene glycol, 0.5-5% isododecane, 1-4% polydimethicone, 0.5-2.5% ethylhexyl salicylate, 0.5-1% phenylbenzimidazole sulfonic acid, 0.5-1% butyloctanol salicylate, 1-4% diisopropyl sebacate, 1-4% diisopropyl adipate, 4-8% vinyl dimethicone / polymethylsilane silsesquioxane crosspolymer, 0.5-1% ethylhexyl triazone, 0.001-0.2% p-hydroxyacetophenone, 2-6% disteardimonium hectorite, 0.5-2% aluminum hydroxide, 1-3% kava leaf / root / stem extract, 0.8-2.8% gentian extract and the balance water; The preparation method of the Piper methysticum leaf / root / stem extract comprises the following steps: S1: mixing the leaves, roots and stems of Piper methysticum in a mass ratio of 1:0.5-1:0.2-0.5, crushing the mixture to obtain a crushed material, adding water 8-40 times the mass of the crushed material, boiling the mixture, stirring the mixture at 60-80° C. for 1-3 hours, and cooling the mixture to obtain a cooled material; S2: adding ginger protease and serrapeptase to the cooled material, performing enzymatic hydrolysis at 40-60° C. for 2-6 hours, inactivating the enzymes, and obtaining an enzymatic hydrolyzate; wherein the total amount of ginger protease and serrapeptase added to each gram of the cooled material is 1500-2000 U, and the ratio of ginger protease to serrapeptase is 2-4:1; S3: adding anhydrous ethanol to the enzymatic hydrolysate to adjust the ethanol mass concentration to 40-60%, heating to 50-60° C. and stirring to perform extraction for 2-5 hours, filtering, concentrating, and drying to obtain the Piper methysticum leaf / root / stem extract; The preparation method of the gentian extract comprises: (1) crushing the plant gentian to obtain plant powder, adding a 50-70% ethanol aqueous solution with a mass concentration of 10-40 times the mass of the powder, heating and stirring at 50-65° C. for 4-8 hours to obtain material A; (2) Material A is concentrated under reduced pressure to 0.25-0.45 times the mass of the plant powder to obtain a concentrate, and a composite extractant of 20-40 times the mass of the concentrate is added, and the mixture is extracted at 40-50° C. for 2-6 hours, and the mixture is allowed to stand for stratification. The organic phase is taken and concentrated under reduced pressure until the extractant component cannot be detected to obtain the gentian extract; The composite extractant is composed of an organic phase and an aqueous phase in a mass ratio of 3-5:1; the organic phase is composed of ethyl acetate and cyclohexane in a mass ratio of 1:0.5-0.8, and the aqueous phase is water.

2. A method for preparing the soothing, long-lasting, sun-protective isolation cream according to claim 1, characterized in that: The steps include: Step 1: Add disteardimethylammonium hectorite and water into a container, heat to 50-70° C., and stir at 300-3000 rpm for 0.1-3 hours to obtain a mixture 1; Step 2: Add butylene glycol, isododecane, polydimethylsiloxane, ethylhexyl salicylate, phenylbenzimidazole sulfonic acid, butyloctanol salicylate, diisopropyl sebacate, diisopropyl adipate, vinyl polydimethylsiloxane / polymethylsilane silsesquioxane crosspolymer, ethylhexyl triazone, and p-hydroxyacetophenone into a container, heat to 70-85° C., and stir at 50-600 rpm for 0.1-2 hours to obtain a mixture 2; Step 3: Add mixture 1 to mixture 2, and stir at 60-400 rpm for 0.1-1 hour; cool, add the remaining raw materials, continue stirring for 0.1-1 hour, let stand for aging, and sterilize to obtain the soothing, long-lasting, sunscreen isolation cream.

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