Traditional Chinese medicine preparation for treating depression state and preparation method thereof

Abstract

The invention discloses a traditional Chinese medicine preparation for treating depressive state and a preparation method thereof, and the traditional Chinese medicine preparation comprises the following components in parts by weight: 35-55 parts of jujube, 20-45 parts of hawthorn, 5-12 parts of ginseng, 13-28 parts of radix bupleuri, 15-32 parts of pericarpium citri reticulatae, 10-20 parts of liquorice, 18-38 parts of spina date seed, 8-15 parts of radix paeoniae alba, 6-12 parts of fructus aurantii, 4-10 parts of pinellia ternate, 6-15 parts of mangnolia officinalis, 8-12 parts of poria cocos, 10-16 parts of caulis perllae and 8-18 parts of Huai wheat. The method specifically comprises the following steps: (1) preparing raw materials: proportioning the raw materials, cleaning and airing; (2) preparing main materials: slicing Chinese dates, hawthorn fruits and ginseng, wrapping with cloth, steaming, mashing and drying to obtain a main material A; and (3) preparing auxiliary materials: grinding radix bupleuri, pericarpium citri reticulatae, liquorice, spina date seeds, radix paeoniae alba, fructus aurantii, pinellia ternate, mangnolia officinalis, poria cocos, caulis perllae and Huai wheat into powder, adding water, and decocting to obtain filtrate. The invention relates to the technical field of traditional Chinese medicine preparations, and particularly provides a traditional Chinese medicine preparation for treating depression and a preparation method thereof.

Description

Technical Field

[0001] The invention relates to the technical field of Chinese medicine preparations, in particular to a Chinese medicine preparation for treating depression and a preparation method thereof. Background Art

[0002] Depression is a typical condition of depressive disorder, with a high prevalence and high clinical cure rate, and its main clinical feature is significant and persistent low mood. Western medicine generally uses antidepressants or sedatives to alleviate the condition, with obvious effects, but the treatment only stays on the surface of the disease and cannot cure it. At the same time, Western medicine has large toxic side effects and is prone to drug resistance.

[0003] In traditional Chinese medicine, depression is attributed to depression syndrome, which is related to emotional disorder and qi stagnation, and can cause symptoms such as irritability, insomnia, anxiety, and restlessness. Emotional discomfort and qi stagnation are the main pathogenesis, which manifests as depression and restlessness. Traditional Chinese medicine treatment methods use Chinese medicine treatment supplemented by acupuncture and massage, and actively regulate mood, eat a reasonable diet and sleep; among them, Chinese medicine preparations are based on the principle of syndrome differentiation and treatment, and can relieve depression, relieve depression, and remove heat, but the actual treatment of depression is slow and the effect is not significant enough. At the same time, the raw materials are complicated, the preparation process is complex, and there are situations where multiple Chinese medicinal materials affect each other. Summary of the invention

[0004] The technical problem to be solved by the present invention is that the current Chinese medicine for depression treatment mainly focuses on relieving depression, relieving depression and removing fire, but the effect is slow and not significant enough, the raw materials are complicated and the preparation is auxiliary, and there is also the situation of drug properties affecting.

[0005] The present invention provides the following technical invention: A Chinese medicine preparation for treating depression proposed by the present invention comprises the following components in parts by weight: 35-55 parts of jujube, 20-45 parts of hawthorn, 5-12 parts of ginseng, 13-28 parts of bupleurum, 15-32 parts of tangerine peel, 10-20 parts of liquorice, 18-38 parts of spiny jujube seeds, 8-15 parts of white peony root, 6-12 parts of bitter orange, 4-10 parts of pinellia, 6-15 parts of magnolia bark, 8-12 parts of poria, 10-16 parts of sophora flavescens, and 8-18 parts of Huai wheat.

[0006] Preferably, the following components are included in parts by weight: 42-50 parts of jujube, 25-38 parts of hawthorn, 8-10 parts of ginseng, 15-26 parts of bupleurum, 15-26 parts of tangerine peel, 12-18 parts of licorice, 22-32 parts of spinach kernel, 9-13 parts of white peony, 8-11 parts of bitter orange, 6-9 parts of pinellia, 7-12 parts of magnolia bark, 9-11 parts of poria, 11-15 parts of sophora flavescens, and 10-16 parts of Huai wheat.

[0007] Preferably, the following components are included in parts by weight: 42 parts of jujube, 25 parts of hawthorn, 8 parts of ginseng, 15 parts of bupleurum, 15 parts of tangerine peel, 12 parts of licorice, 22 parts of spiny jujube seeds, 9 parts of white peony root, 8 parts of bitter orange, 6 parts of pinellia, 7 parts of magnolia bark, 9 parts of poria, 11 parts of sophora japonica stem, and 10 parts of Huai wheat.

[0008] Preferably, the following components are included in parts by weight: 50 parts of jujube, 45 parts of hawthorn, 12 parts of ginseng, 28 parts of bupleurum, 26 parts of tangerine peel, 18 parts of licorice, 32 parts of spiny jujube seeds, 9 parts of white peony, 8 parts of bitter orange, 6 parts of pinellia, 7 parts of magnolia bark, 9 parts of poria, 11 parts of sophora japonica stem, and 10 parts of Huai wheat.

[0009] Preferably, the following components are included in parts by weight: 45 parts of jujube, 28 parts of hawthorn, 8 parts of ginseng, 18 parts of bupleurum, 22 parts of tangerine peel, 16 parts of licorice, 24 parts of spiny jujube seeds, 11 parts of white peony root, 10 parts of bitter orange, 7 parts of pinellia, 9 parts of magnolia bark, 10 parts of poria, 12 parts of sophora japonica stem, and 14 parts of Huai wheat.

[0010] The present invention provides a method for preparing a Chinese medicine preparation for treating depression, which specifically comprises the following steps:

[0011] (1) Raw material preparation: Mix the raw materials, clean them and dry them;

[0012] (2) Preparation of main ingredients: slice jujube, hawthorn and ginseng, wrap them in cloth, steam and crush them, and dry them to obtain main ingredient A;

[0013] (3) Preparation of auxiliary materials: Grind bupleurum, dried orange peel, liquorice, spiny jujube seed, white peony root, fructus aurantii, pinellia tuber, magnolia bark, poria, stem of perilla, and Huai wheat into powder, add water and boil to obtain a filtrate;

[0014] (4) Mixing: Main ingredient A and secondary filtrate are mixed and stirred thoroughly, and main ingredient A absorbs secondary filtrate;

[0015] (5) Compression and packaging: The mixed material is pressed into pellets and packaged.

[0016] Furthermore, the preparation of auxiliary materials includes primary boiling and secondary boiling. In the primary boiling, 10 times the amount of water as the raw material is added for boiling, and the mixture is boiled over high heat and then boiled over low heat for 1 to 2 hours, and the primary filtrate and filter residue are obtained by filtering. In the secondary boiling, the filter residue is boiled with 5 times the amount of water as the raw material, and the filtered filtrate is mixed with the previous filtrate to obtain a secondary filtrate.

[0017] Furthermore, the filter residue after boiling in the preparation of the auxiliary material is filtered through a 200-300 mesh screen to ensure viscosity while preventing smaller impurities from affecting the taste.

[0018] Furthermore, in the preparation of the auxiliary material, the powder is sieved using a 800-1200 mesh screen after grinding.

[0019] It can be taken directly orally or dissolved in warm water for consumption.

[0020] The present invention proposes a Chinese medicine preparation for treating depression and a preparation method thereof. The beneficial effects achieved by adopting the above scheme are as follows:

[0021] (1) Jujube is warm in nature and sweet in taste. It has the effects of tonifying the middle qi, nourishing blood and calming the mind. It is suitable for weak spleen and stomach and loss of appetite. Hawthorn can invigorate the stomach and digestion, promote qi and dissipate blood stasis, and remove turbidity and reduce fat. It is combined with ginseng to nourish the spleen and lungs, promote fluid and nourish blood to form the main raw materials. The mixture is steamed and mixed to strengthen the spleen and stomach, increase appetite, promote qi and dissipate blood stasis, and tonify the spleen and lungs. The three complement each other.

[0022] (2) Bupleurum root can dispel heat, soothe the liver and relieve depression; dried tangerine peel can regulate qi and strengthen the spleen, dry dampness and resolve phlegm; liquorice has the properties and tastes of meridians, tonifies the spleen and replenishes qi, clears away heat and detoxifies; spinach seed nourishes the heart and liver, calms the mind and soothes the nerves; supplemented with white peony root, bitter orange peel, pinellia tuber, magnolia bark, tuckahoe, sophora root, and Huai wheat, it can relieve loss of appetite, mental tension, emotional instability, and depression; bupleurum root, dried tangerine peel, liquorice, spinach seed, white peony root, bitter orange peel, pinellia tuber, magnolia bark, tuckahoe, sophora root, and Huai wheat are ground into powder and boiled twice to obtain a filtrate, which is then fully mixed with mixed steamed jujube, hawthorn, and ginseng to make pills. The preparation process is simple and the pills are convenient to carry and eat. DETAILED DESCRIPTION

[0023] The following will clearly and completely describe the technology in the embodiments of the present invention in conjunction with the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all of the embodiments; based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0024] Example 1

[0025] A Chinese medicine preparation for treating depression comprises the following components in parts by weight: 45 parts of jujube, 28 parts of hawthorn, 8 parts of ginseng, 18 parts of bupleurum, 22 parts of dried orange peel, 16 parts of liquorice, 24 parts of spiny jujube seeds, 9 parts of white peony root, 8 parts of bitter orange, 6 parts of pinellia, 7 parts of magnolia bark, 9 parts of poria, 11 parts of sophora japonica stem and 10 parts of Huai wheat.

[0026] The present invention provides a method for preparing a Chinese medicine preparation for treating depression, which specifically comprises the following steps:

[0027] (1) Raw material preparation: Mix the raw materials, clean them and dry them;

[0028] (2) Preparation of main ingredients: slice jujube, hawthorn and ginseng, wrap them in cloth, steam and crush them, and dry them to obtain main ingredient A;

[0029] (3) Preparation of auxiliary materials: Grind radix bupleuri, dried tangerine peel, liquorice, spiny jujube seeds, white peony root, fructus aurantii, pinellia tuber, magnolia bark, poria, stem of sophora japonica, and Huai wheat into powder, sieve through a 800-mesh sieve, add 10 times the amount of water of the raw materials to boil for the first time, boil over high heat until boiling and then simmer for 1 hour, filter to obtain a primary filtrate and a filter residue; add 5 times the amount of water of the raw materials to boil for the second time, filter and mix the filtrates on both sides to obtain a secondary filtrate, wherein the filter residue is filtered through a 200-mesh sieve;

[0030] (4) Mixing: Main ingredient A and secondary filtrate are mixed and stirred thoroughly, and main ingredient A absorbs secondary filtrate;

[0031] (5) Compression and packaging: The mixed material is pressed into pellets and packaged.

[0032] Example 2

[0033] A Chinese medicine preparation for treating depression comprises the following components in parts by weight: 35 parts of jujube, 22 parts of hawthorn, 10 parts of ginseng, 25 parts of bupleurum, 28 parts of dried orange peel, 19 parts of liquorice, 30 parts of spiny jujube seeds, 9 parts of white peony root, 8 parts of bitter orange, 6 parts of pinellia, 7 parts of magnolia bark, 9 parts of poria, 11 parts of sophora japonica stem and 10 parts of Huai wheat.

[0034] The present invention provides a method for preparing a Chinese medicine preparation for treating depression, which specifically comprises the following steps:

[0035] (1) Raw material preparation: Mix the raw materials, clean them and dry them;

[0036] (2) Preparation of main ingredients: slice jujube, hawthorn and ginseng, wrap them in cloth, steam and crush them, and dry them to obtain main ingredient A;

[0037] (3) Preparation of auxiliary materials: Grind bupleurum, dried orange peel, liquorice, spiny jujube seed, white peony root, fructus aurantii, pinellia tuber, magnolia bark, poria, stem of sophora japonica, and Huai wheat into powder, sieve through a 1000-mesh sieve, add 8 times the amount of water as the raw materials for the first boiling, boil over high heat until boiling and then simmer over low heat for 2 hours, filter to obtain a first filtrate and a filter residue; for the second boiling, add 4 times the amount of water as the raw materials to the filter residue and boil, filter and mix the filtrates on both sides to obtain a second filtrate, wherein the filter residue is filtered through a 180-mesh sieve;

[0038] (4) Mixing: Main ingredient A and secondary filtrate are mixed and stirred thoroughly, and main ingredient A absorbs secondary filtrate;

[0039] (5) Compression and packaging: The mixed material is pressed into pellets and packaged.

[0040] Example 3

[0041] A traditional Chinese medicine preparation for treating depression comprises the following components in parts by weight: 55 parts of jujube, 45 parts of hawthorn, 12 parts of ginseng, 28 parts of bupleurum, 32 parts of dried orange peel, 20 parts of liquorice, 35 parts of spiny jujube seeds, 9 parts of white peony root, 8 parts of fructus aurantii, 6 parts of pinellia, 7 parts of magnolia bark, 9 parts of poria, 11 parts of sophora japonica stem and 10 parts of Huai wheat.

[0042] The present invention provides a method for preparing a Chinese medicine preparation for treating depression, which specifically comprises the following steps:

[0043] (1) Raw material preparation: Mix the raw materials, clean them and dry them;

[0044] (2) Preparation of main ingredients: slice jujube, hawthorn and ginseng, wrap them in cloth, steam and crush them, and dry them to obtain main ingredient A;

[0045] (3) Preparation of auxiliary materials: Grind radix bupleuri, dried tangerine peel, liquorice, spiny jujube seeds, white peony root, fructus aurantii, pinellia tuber, magnolia bark, poria, stem of sophora japonica, and Huai wheat into powder, sieve through a 1200-mesh sieve, add 6 times the amount of water as the raw materials for the first boiling, boil over high heat until boiling and then simmer for 1 hour, filter to obtain a first filtrate and a filter residue; for the second boiling, add 3 times the amount of water as the raw materials to the filter residue and boil, filter and mix the filtrates on both sides to obtain a second filtrate, wherein the filter residue is filtered through a 300-mesh sieve;

[0046] (4) Mixing: Main ingredient A and secondary filtrate are mixed and stirred thoroughly, and main ingredient A absorbs secondary filtrate;

[0047] (5) Compression and packaging: The mixed material is pressed into pellets and packaged.

[0048] Example 4

[0049] A Chinese medicine preparation for treating depression comprises the following components in parts by weight: 35 parts of jujube, 40 parts of hawthorn, 5 parts of ginseng, 15 parts of bupleurum, 32 parts of dried tangerine peel, 20 parts of liquorice, 22 parts of spiny jujube seeds, 11 parts of white peony root, 10 parts of bitter orange fructus, 7 parts of pinellia, 9 parts of magnolia bark, 10 parts of poria, 12 parts of sophora japonica stem and 14 parts of Huai wheat.

[0050] The present invention provides a method for preparing a Chinese medicine preparation for treating depression, which specifically comprises the following steps:

[0051] (1) Raw material preparation: Mix the raw materials, clean them and dry them;

[0052] (2) Preparation of main ingredients: slice jujube, hawthorn and ginseng, wrap them in cloth, steam and crush them, and dry them to obtain main ingredient A;

[0053] (3) Preparation of auxiliary materials: Grind radix bupleuri, dried tangerine peel, liquorice, spiny jujube seeds, white peony root, fructus aurantii, pinellia tuber, magnolia bark, poria, stem of sophora japonica, and triticale into powder, sieve through a 1200-mesh sieve, add 10 times the amount of water of the raw materials to boil for the first time, boil over high heat until boiling and then simmer for 2 hours, filter to obtain a primary filtrate and a filter residue; add 5 times the amount of water of the raw materials to boil for the second time, filter and mix the filtrates on both sides to obtain a secondary filtrate, wherein the filter residue is filtered through a 300-mesh sieve;

[0054] (4) Mixing: Main ingredient A and secondary filtrate are mixed and stirred thoroughly, and main ingredient A absorbs secondary filtrate;

[0055] (5) Compression and packaging: The mixed material is pressed into pellets and packaged.

[0056] Example 5

[0057] A Chinese medicine preparation for treating depression comprises the following components in parts by weight: 35 parts of jujube, 22 parts of hawthorn, 5 parts of ginseng, 15 parts of bupleurum, 32 parts of dried orange peel, 20 parts of liquorice, 22 parts of spiny jujube seeds, 11 parts of white peony root, 10 parts of bitter orange, 7 parts of pinellia, 9 parts of magnolia bark, 10 parts of poria, 12 parts of sophora japonica stem and 14 parts of Huai wheat.

[0058] The present invention provides a method for preparing a Chinese medicine preparation for treating depression, which specifically comprises the following steps:

[0059] (1) Raw material preparation: Mix the raw materials, clean them and dry them;

[0060] (2) Preparation of main ingredients: slice jujube, hawthorn and ginseng, wrap them in cloth, steam and crush them, and dry them to obtain main ingredient A;

[0061] (3) Preparation of auxiliary materials: Grind radix bupleuri, dried tangerine peel, liquorice, spiny jujube seeds, white peony root, fructus aurantii, pinellia tuber, magnolia bark, poria, stem of sophora japonica, and Huai wheat into powder, sieve through a 1200-mesh sieve, add 8 times the amount of water as the raw materials for the first boiling, boil over high heat until boiling and then simmer over low heat for 2 hours, filter to obtain a first filtrate and a filter residue; for the second boiling, add 4 times the amount of water as the raw materials to the filter residue and boil, filter and mix the filtrates on both sides to obtain a second filtrate, wherein the filter residue is filtered through a 300-mesh sieve;

[0062] (4) Mixing: Main ingredient A and secondary filtrate are mixed and stirred thoroughly, and main ingredient A absorbs secondary filtrate;

[0063] (5) Compression and packaging: The mixed material is pressed into pellets and packaged.

[0064] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprises" or any other variations thereof are intended to cover non-exclusive inclusion, so that a process, method, material or apparatus including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, material or apparatus.

[0065] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A Chinese medicine preparation for treating depression, characterized in that: The invention comprises the following components in parts by weight: 35-55 parts of jujube, 20-45 parts of hawthorn, 5-12 parts of ginseng, 13-28 parts of bupleurum, 15-32 parts of dried orange peel, 10-20 parts of liquorice, 18-38 parts of spiny jujube kernel, 8-15 parts of white peony root, 6-12 parts of bitter orange, 4-10 parts of pinellia, 6-15 parts of magnolia bark, 8-12 parts of poria, 10-16 parts of sophora japonica stem and 8-18 parts of Huai wheat.

2. A Chinese medicine preparation for treating depression according to claim 1, characterized in that: The invention comprises the following components in parts by weight: 42-50 parts of jujube, 25-38 parts of hawthorn, 8-10 parts of ginseng, 15-26 parts of bupleurum, 15-26 parts of dried orange peel, 12-18 parts of liquorice, 22-32 parts of spinach seeds, 9-13 parts of white peony root, 8-11 parts of bitter orange, 6-9 parts of pinellia, 7-12 parts of magnolia bark, 9-11 parts of poria, 11-15 parts of sophora japonica stem and 10-16 parts of Huai wheat.

3. A Chinese medicine preparation for treating depression according to claim 1, characterized in that: The invention comprises the following components in parts by weight: 42 parts of jujube, 25 parts of hawthorn, 8 parts of ginseng, 15 parts of bupleurum, 15 parts of dried orange peel, 12 parts of liquorice, 22 parts of spiny jujube seeds, 9 parts of white peony root, 8 parts of fructus aurantii, 6 parts of pinellia, 7 parts of magnolia bark, 9 parts of poria, 11 parts of sophora japonica stem and 10 parts of Huai wheat.

4. A Chinese medicine preparation for treating depression according to claim 1, characterized in that: The invention comprises the following components in parts by weight: 50 parts of jujube, 45 parts of hawthorn, 12 parts of ginseng, 28 parts of bupleurum, 26 parts of dried orange peel, 18 parts of liquorice, 32 parts of spiny jujube kernel, 9 parts of white peony root, 8 parts of bitter orange, 6 parts of pinellia, 7 parts of magnolia bark, 9 parts of poria, 11 parts of sophora japonica stem and 10 parts of Huai wheat.

5. A Chinese medicine preparation for treating depression according to claim 1, characterized in that: The invention comprises the following components in parts by weight: 45 parts of jujube, 28 parts of hawthorn, 8 parts of ginseng, 18 parts of bupleurum, 22 parts of dried orange peel, 16 parts of liquorice, 24 parts of spiny jujube seeds, 11 parts of white peony root, 10 parts of bitter orange peel, 7 parts of pinellia, 9 parts of magnolia bark, 10 parts of poria, 12 parts of sophora japonica stem and 14 parts of Huai wheat.

6. A method for preparing a Chinese medicine preparation for treating depression according to any one of claims 1 to 5, characterized in that: The specific steps include: (1) Raw material preparation: Mix the raw materials, clean them and dry them; (2) Preparation of main ingredients: slice jujube, hawthorn and ginseng, wrap them in cloth, steam and crush them, and dry them to obtain main ingredient A; (3) Preparation of auxiliary materials: Grind bupleurum, dried orange peel, liquorice, spiny jujube seed, white peony root, fructus aurantii, pinellia tuber, magnolia bark, poria, stem of perilla, and Huai wheat into powder, add water and boil to obtain a filtrate; (4) Mixing: Main ingredient A and secondary filtrate are mixed and stirred thoroughly, and main ingredient A absorbs secondary filtrate; (5) Compression and packaging: The mixed material is pressed into pellets and packaged.

7. The method for preparing a Chinese medicine preparation for treating depression according to claim 6, characterized in that: The preparation of the auxiliary material includes a primary boiling and a secondary boiling. In the primary boiling, 10 times the amount of water of the raw material is added for boiling, and the mixture is boiled over high heat and then boiled over low heat for 1 to 2 hours, and a primary filtrate and a filter residue are obtained by filtering. In the secondary boiling, the filter residue is boiled by adding 5 times the amount of water of the raw material, and the filtered filtrate is mixed with the previous filtrate to obtain a secondary filtrate.

8. The method for preparing a Chinese medicine preparation for treating depression according to claim 7, characterized in that: The filter residue after boiling in the preparation of the auxiliary material is filtered through a 200-300 mesh screen to ensure viscosity while preventing smaller impurities from affecting the taste.

9. The method for preparing a Chinese medicine preparation for treating depression according to claim 8, characterized in that: In the preparation of the auxiliary materials, the powder is ground and then sieved using a 800-1200 mesh sieve.