Traditional Chinese medicine composition for relieving eyestrain and application thereof

Abstract

The invention belongs to the technical field of traditional Chinese medicine preparations, and particularly relates to a traditional Chinese medicine composition for relieving eyestrain and application thereof. The traditional Chinese medicine composition for relieving eyestrain is prepared from the following components: kiwi fruit vine, rhizoma acori graminei, folium mori, flos chrysanthemi, radix bupleuri, poria cocos, cortex moutan, semen cuscutae, fructus schisandrae chinensis, fructus ligustri lucidi, uncaria and herba taraxaci. According to the traditional Chinese medicine composition for relieving eyestrain, the kiwi fruit vines and the rhizoma acori graminei are used together and serve as monarch drugs, the folium mori, the flos chrysanthemi, the radix bupleuri, the poria cocos and the cortex moutan serve as ministerial drugs, the other five drugs serve as adjuvant and conductant drugs, all the drugs are used together, cold and warm are used together, and an agent for clearing liver and improving eyesight is formed. The eye protection pouch prepared according to the composition prescription can safely and effectively relieve eyestrain, and the eye protection pouch is simple in preparation process and low in production cost and has a wide market application prospect.

Description

Technical Field

[0001] The invention belongs to the technical field of traditional Chinese medicine preparations, and particularly relates to a traditional Chinese medicine composition for relieving eye fatigue and an application thereof. Background Art

[0002] In recent years, the incidence of myopia in my country has remained high, and myopia has become a major public health problem that affects the eye health of Chinese people, especially children and adolescents. How to relieve myopia, eye fatigue, tension and other problems has become a hot topic in modern medicine. After excessive use of the eyes, patients will focus their sight on nearby objects for a long time, and the eyes need to continuously use the adjustment force to see the nearby scenery clearly. Over time, it is easy to cause the ciliary muscles inside the eyeball to spasm after excessive contraction, resulting in spasm pain, causing patients to experience symptoms of sore and painful eyes. Since the main function of the ciliary muscle is to adjust the position of the patient's sight focus, so that they can see clearly the scenery at different distances far or near. When the ciliary muscle spasms, the function of adjusting the focus will be temporarily suppressed, and the patient will have a short period of blurred vision. In addition, the pain nerves in the eyes are widely distributed and sensitive. When the ciliary muscle spasms, it may cause referred pain in the head, and the patient will have symptoms such as dizziness and nausea.

[0003] Traditional Chinese medicine believes that the liver opens up to the eyes, and eye fatigue is often related to factors such as excessive use of the eyes, refractive errors, and physical weakness. It is caused by long-term vision, mental fatigue, loss of qi and blood, stagnation of the meridians in the eyes, and insufficient liver and kidney essence and blood, which leads to poor eye nourishment and regulation. The disease is often related to the liver, heart, and kidney. Treatment should be to replenish qi and blood, nourish the liver and kidney, and clear the liver and improve eyesight.

[0004] At present, there are not many types of Chinese medicine preparations for relieving eye fatigue, and most of them use Western medicine in clinical practice, but the effect is limited. In the prior art, China's patent application CN116173122A discloses a herbal eye ointment, which is made by adding dispersants and gelling agents after high-temperature decoction, filtration and concentration of 19 Chinese medicinal materials such as bear bile and saffron. A variety of precious Chinese medicinal materials are used in the formula, the production cost is high, and the process flow is complicated. China's patent application CN112704705A discloses a Chinese medicine eye patch for relieving visual fatigue, which is made of mulberry leaves, safflower, mint and other medicinal materials into four types of eye patches for people with different physiques. The patent component is streamlined and has a certain clinical efficacy, but in actual application, consumers need to choose the eye patch suitable for themselves by self-testing their Chinese medicine constitution, which increases the difficulty of clinical use.

[0005] Based on the above problems, the present invention combines classical Chinese medicine theory, and after a large amount of prescription research, adopts twelve common Chinese medicinal materials to rationally combine into a prescription, aiming to provide a safe and effective eye protection product with a simple preparation process, which is suitable for daily eye care for all kinds of people and suitable for large-scale market promotion.

[0006] Kiwi vine is the dried root and vine stem of Actinidia chinensis Planch., a plant of the Actinidiaceae family. It is cold in nature, sour and bitter in taste, and enters the stomach, liver, and kidney meridians. It has the effects of clearing away heat and detoxifying, harmonizing the middle and removing dampness, promoting blood circulation and dispersing stagnation. It is used to treat scrofula, jaundice, indigestion, stranguria, leucorrhea, milk retention, injuries from falls, carbuncles, boils, and cancers. It is a traditional medicinal material used by ethnic minorities in Guizhou Province.

[0007] Acorus tatarinowii Schott is the dried rhizome of Acorus tatarinowii Schott, a plant of the Araceae family. It is warm in nature, pungent and bitter in taste, and enters the heart and stomach meridians. It has the effects of opening the orifices and removing phlegm, refreshing the mind and improving intelligence, removing dampness and stimulating appetite. It is used to treat coma, epilepsy, forgetfulness, insomnia, tinnitus, deafness, abdominal distension without hunger, and dysentery with lockjaw.

[0008] Mulberry leaf is the dried leaf of Morus alba L., a plant of the Moraceae family. It is cold in nature, sweet and bitter in taste, and enters the lung and liver meridians. It has the effects of dispersing wind-heat, clearing the lungs and moistening dryness, clearing the liver and improving eyesight, and is used to treat wind-heat colds, lung heat and dry coughs, dizziness and headaches, and red and blurred eyes.

[0009] Chrysanthemum is the dried inflorescence of Chrysanthemum morifolium Ramat., a plant of the Asteraceae family. It is slightly cold in nature, sweet and bitter in taste, and enters the lung and liver meridians. It has the effects of dispersing wind and heat, calming the liver and improving eyesight, clearing heat and detoxifying, and is used to treat wind-heat colds, headaches and dizziness, red and swollen eyes, blurred vision, sores, carbuncles, and swelling.

[0010] Bupleurum is the dried root of Bupleurum chinense DC. or Bupleurumscorzonerifolium Willd. of the Umbelliferae family. It is slightly cold in nature, pungent and bitter in taste, and enters the liver, gallbladder, and lung meridians. It has the effects of dispersing heat, relieving liver depression, and raising Yang Qi. It is used to treat colds and fever, alternating cold and heat, chest and flank pain, irregular menstruation, uterine prolapse, and rectal prolapse.

[0011] Poria cocos is the dried sclerotium of the Polyporaceae fungus Poria cocos (Schw.) Wolf. It is flat in nature, sweet and light in taste, and enters the heart, lung, spleen, and kidney meridians. It has the effects of promoting diuresis and eliminating dampness, strengthening the spleen, and calming the mind. It is used to treat edema, oliguria, phlegm and fluid, dizziness and palpitations, spleen deficiency and poor appetite, loose stools and diarrhea, restlessness, palpitations and insomnia.

[0012] Peony is the dried root bark of Paeonia suffruticosa Andr., a plant of the Ranunculaceae family. It is slightly cold in nature, bitter and pungent in taste, and enters the heart, liver, and kidney meridians. It has the effects of clearing heat and cooling blood, promoting blood circulation and resolving phlegm. It is used to treat heat entering the blood, fever and rashes, vomiting blood and epistaxis, night heat and morning coolness, no sweating and bone steaming, amenorrhea and dysmenorrhea, injuries and pains from falls, and carbuncles and sores.

[0013] Cuscuta australis R.Br. or Cuscutachinensis Lam., a plant of the Convolvulaceae family, is a dry, mature seed. It is pungent and sweet in taste, neutral in nature, and enters the liver, kidney, and spleen meridians. It has the effects of nourishing the liver and kidney, consolidating the essence and reducing urine, calming the fetus, improving eyesight, and stopping diarrhea. It can be used externally to eliminate wind and remove spots. It is used to treat liver and kidney deficiency, soreness of the waist and knees, impotence and spermatorrhea, enuresis and frequent urination, kidney deficiency and fetal leakage, restless fetal movement, blurred vision and tinnitus, spleen and kidney deficiency diarrhea, and external treatment of vitiligo.

[0014] Schisandra chinensis (Turcz.) Baill., a plant of the Magnoliaceae family, is a dried mature fruit, commonly known as "Northern Schisandra". It is sour and sweet, warm in nature, and enters the lung, heart, and kidney meridians. It has the effects of astringing, strengthening qi and promoting body fluid, tonifying the kidney and calming the mind. It is used to treat chronic cough, weak asthma, nocturnal emission, frequent urination, chronic diarrhea, spontaneous sweating, night sweats, thirst due to loss of body fluid, internal heat and thirst, palpitations and insomnia.

[0015] Ligustrum lucidum fruit is the dried mature fruit of Ligustrum lucidum Ait., a plant of Oleaceae. It tastes sweet and bitter, is cool in nature, and enters the liver and kidney meridians. It has the effects of nourishing the liver and kidney, improving eyesight and darkening hair, and is used to treat liver and kidney yin deficiency, dizziness and tinnitus, soreness of waist and knees, premature graying of hair, blurred vision, internal heat and thirst, and bone steaming and hot flashes.

[0016] Uncaria rhynchophylla is the dried hooked stems and branches of Uncaria rhynchophylla (Miq.) Jacks., Uncaria macrophylla Wall., Uncaria hirsuta Havil., Uncaria sinensis (Oliv.) Havil. or Uncaria sessilifructus Roxb. of the Rubiaceae family. It is sweet in taste and cool in nature. It enters the liver and pericardium meridians. It has the effects of clearing away heat and calming the liver, calming wind and calming convulsions. It is used to treat headache and dizziness, cold and convulsions, epilepsy and convulsions, eclampsia during pregnancy, and hypertension.

[0017] Dandelion is the dried whole herb of Taraxacum mongolicum Hand.-Mazz., Taraxacum borealisinense Kitam. or several plants of the same genus in the Asteraceae family. It tastes bitter and sweet, is cold in nature, and enters the liver and stomach meridians. It has the effects of clearing away heat and detoxifying, reducing swelling and dispersing knots, and promoting diuresis and relieving stranguria. It is used to treat carbuncle, breast carbuncle, scrofula, red eyes, sore throat, lung carbuncle, intestinal carbuncle, damp-heat jaundice, and hot stranguria.

[0018] Kiwi vines harmonize the stomach, protect the membranes and strengthen the spleen. The spleen and stomach function well, Qi and blood are produced, the five internal organs are nourished, and the essence is infused into the eyes. Acorus calamus has the essence of cold water, which can moisten the orifices of the five internal organs, nourish the five internal organs internally, and connect the nine orifices externally. Therefore, Acorus calamus is used to wake up the mind, improve intelligence, and improve eyesight and hearing. The two medicines are used together, which can not only make Qi and blood produce active, nourish the eyes, but also improve hearing and eyesight. They are both the main medicines. Mulberry leaves are sweet and cold in nature. The combination of sweetness and coldness can moisten and nourish yin to improve eyesight. Chrysanthemum enters the liver meridian and can both disperse wind-heat in the liver meridian and clear liver heat to improve eyesight. The two medicines complement each other and go straight to the upper part of the body. They work together to clear the liver and improve eyesight. The Shaoyang meridian runs behind the ear, through the cheek to the underside of the eye socket. In the early stage of eye fatigue, you may feel eye socket pain. Chaihu disperses the evil of Shaoyang half-exterior and half-interior to relieve pain. The evil of drink invades the upper part, and the clear yang does not rise, so there is dizziness. The sweet and light Poria can strengthen the spleen and benefit water, penetrate dampness and transform drink, and eliminate the source of phlegm (drink). The liver is the organ of wind and wood. The liver wind and turbid fire go up, and the symptoms of eye fatigue arise. The pungent and cold Cortex Moutan is used as the minister to clear liver fire, so all symptoms can be relieved. The five medicines are used together to clear the liver and improve eyesight, relieve pain, and stop dizziness. They are all minister medicines. The deficiency of liver and kidney essence and blood, the loss of nourishment of tendons, and the regulation is dysfunctional, resulting in dry eyes. The Shennong's Herbal Classic records that Cuscuta chinensis can "replenish deficiency, improve qi and strength, make people healthy, and improve eyesight after long-term use, lighten the body and prolong life." Cuscuta chinensis can nourish the liver and kidney, improve eyesight and remove cataracts. When combined with Schisandra chinensis, it can enhance the effect of nourishing the kidney and astringing essence. When combined with Ligustrum lucidum, it nourishes the liver and kidney, nourishes the liver and improves eyesight. The three herbs are used together to nourish the liver and kidney, improve essence and blood, and are adjuvants. Uncaria rhynchophylla is cool in nature and mainly enters the liver meridian. It can clear liver heat and calm liver yang. Taraxacum mongolicum is bitter and cold in nature. It enters the liver meridian and has the effect of clearing the liver and improving eyesight. The two herbs are used together to further improve the effect of clearing the liver and improving eyesight, and can also lead the other herbs in the prescription directly to the diseased area, so they are adjuvants. The combination of all the herbs, cold and warm, and tonic and purgative, together form a drug that replenishes qi and blood, nourishes the liver and kidney, and clears the liver and improves eyesight. Summary of the invention

[0019] The purpose of the present invention is to provide a Chinese medicine composition for relieving eye fatigue and application of the Chinese medicine composition in preparing a medicine for relieving eye fatigue and protecting eye bags.

[0020] In order to achieve the above object, the technical solution adopted by the present invention is as follows:

[0021] The traditional Chinese medicine composition for relieving eye fatigue of the present invention comprises the following components in parts by mass: 30 to 50 parts of kiwi vine, 30 to 50 parts of calamus, 5 to 20 parts of mulberry leaves, 5 to 20 parts of chrysanthemum, 5 to 20 parts of bupleurum, 5 to 20 parts of poria, 5 to 20 parts of peony bark, 5 to 20 parts of dodder seeds, 5 to 15 parts of schisandra chinensis, 5 to 15 parts of privet fruits, 5 to 15 parts of Uncaria rhynchophylla and 5 to 15 parts of dandelions.

[0022] Preferably, the traditional Chinese medicine composition for relieving eye fatigue of the present invention comprises the following components in parts by mass: 40 to 50 parts of Actinidia chinensis vine, 40 to 50 parts of Acorus calamus, 10 to 20 parts of mulberry leaves, 10 to 20 parts of chrysanthemum, 10 to 20 parts of Bupleurum, 10 to 20 parts of Poria, 10 to 20 parts of Paeonia suffruticosa, 10 to 20 parts of Cuscuta australis, 10 to 15 parts of Schisandra chinensis, 10 to 15 parts of Ligustrum lucidum, 10 to 15 parts of Uncaria rhynchophylla and 10 to 15 parts of Taraxacum officinale.

[0023] Further preferably, the traditional Chinese medicine composition for relieving eyestrain of the present invention comprises the following components in parts by mass: 40 parts of Actinidia chinensis vine, 40 parts of Acorus calamus, 15 parts of mulberry leaves, 15 parts of chrysanthemum, 15 parts of Bupleurum, 15 parts of Poria, 15 parts of Paeonia suffruticosa, 15 parts of Cuscuta australis, 10 parts of Schisandra chinensis, 10 parts of Ligustrum lucidum, 10 parts of Uncaria rhynchophylla and 10 parts of Taraxacum officinale.

[0024] All components of the traditional Chinese medicine composition of the present invention are processed and prepared medicinal materials.

[0025] The invention discloses an application of the Chinese medicine composition in preparing medicine for alleviating eye fatigue and protecting eye bags.

[0026] The preparation method for relieving eye fatigue and protecting eye bags of the present invention comprises the following steps: processing and preparing medicinal materials such as kiwi vine, calamus, mulberry leaf, chrysanthemum, bupleurum, tuckahoe, peony bark, dodder seed, schisandra chinensis, glossy privet fruit, uncaria and dandelion to obtain purified decoction pieces, and then crushing, mixing, sterilizing and packaging the pieces.

[0027] The preparation method for relieving eye fatigue and protecting eye bags of the present invention specifically comprises the following steps:

[0028] S1: Processing and preparing the medicinal materials of Actinidia chinensis, Acorus calamus, mulberry leaf, chrysanthemum, bupleurum, Poria, peony bark, Cuscuta australis, Schisandra chinensis, Ligustrum lucidum, Uncaria rhynchophylla and Taraxacum mongolicum to obtain the purified decoction pieces;

[0029] S2: Weigh the purified decoction pieces of the twelve medicinal materials prepared above by weight, grind them into powder using a grinder, and pass them through a 20-40 mesh sieve to obtain coarse powder;

[0030] S3: mixing the coarse powders of the 12 medicinal materials crushed into powder to prepare a mixed powder;

[0031] S4: After sterilizing the mixed powder prepared above under moist heat at 105±5°C for 15 min, divide the mixture into non-woven fabric packaging materials to obtain the product.

[0032] In the preparation method for relieving eye fatigue and protecting eye bags of the present invention, the processing described in step S1 is: selecting, soaking, cutting and drying the medicinal materials.

[0033] In the preparation method for relieving eye fatigue and protecting eye bags of the present invention, the drying conditions of the processing and preparation in step S1 are: temperature 50-60° C., 5-6 hours.

[0034] Preferably, in the preparation method for relieving eye fatigue and protecting eye bags of the present invention, the coarse powder in step S2 is obtained by passing through a 20-mesh sieve.

[0035] Beneficial effects of the present invention:

[0036] 1. The present invention provides a Chinese medicine composition that can effectively relieve eye fatigue. Clinical effect verification experiments have confirmed that the total effective rate of the eye bag protection prepared according to the formula of the Chinese medicine composition provided by the present invention for vision treatment is 72%, of which the effective rate for poor vision is as high as 81.82%, and the recovery rate of poor vision reaches 59.09%; through the comparison data of the change in refractive power before and after treatment, it can be seen that the above-mentioned Chinese medicine composition also has a certain therapeutic effect on correcting the eye refractive power, which fully proves that the Chinese medicine composition provided by the present invention has a good therapeutic effect on eye diseases such as myopia, astigmatism, and eye fatigue.

[0037] 2. The present invention provides an eye-protecting eye bag based on the formula of the Chinese medicine composition of the present invention and a preparation method thereof. The eye-protecting eye bag has a simple preparation process, low production cost, significant clinical effect, and has broad market application prospects. BRIEF DESCRIPTION OF THE DRAWINGS

[0038] Figure 1 This is the process flow chart of eye bag protection. DETAILED DESCRIPTION

[0039] The technical solution of the present invention is described in detail below in conjunction with specific embodiments. The following embodiments are only used for explanation and illustration, and do not constitute a limitation on the technical solution of the present invention.

[0040] Example 1

[0041] Prescription of Chinese medicine composition for relieving eye fatigue:

[0042] Kiwi vine 400g Acorus calamus 400g Mulberry leaf 150g Chrysanthemum 150g

[0043] Bupleurum 150g Poria 150g Peony bark 150g Cuscuta chinensis 150g

[0044] Schisandra 100g Ligustrum lucidum 100g Uncaria rhynchophylla 100g Taraxacum mongolicum 100g

[0045] The above-mentioned Chinese medicine composition is used to prepare an eye protection eye bag for relieving eye fatigue, and the preparation method is as follows:

[0046] S1: Select, soak, cut and dry the raw medicinal materials at 50-60°C for 5-6h to obtain purified medicinal pieces;

[0047] S2: Weigh the purified decoction pieces of each raw medicinal material according to the prescription, crush them with a grinder, pass them through a 20-mesh sieve, and obtain coarse powder;

[0048] S3: mixing the coarse powders prepared above evenly to prepare mixed powders;

[0049] S4: After sterilizing the mixed powder prepared above under moist heat at 105±5°C for 15 minutes, the mixed powder is divided into non-woven packaging materials to obtain 1000 bags of finished products.

[0050] Example 2

[0051] Prescription of Chinese medicine composition for relieving eye fatigue:

[0052] Kiwi vine 300g Acorus calamus 300g Mulberry leaf 150g Chrysanthemum 150g

[0053] Bupleurum 150g Poria 150g Peony bark 150g Cuscuta chinensis 150g

[0054] Schisandra 150g Ligustrum lucidum 150g Uncaria rhynchophylla 150g Taraxacum mongolicum 150g

[0055] The above-mentioned Chinese medicine composition is used to prepare an eye protection eye bag for relieving eye fatigue, and the preparation method is as follows:

[0056] S1: Select, soak, cut and dry the raw medicinal materials at 50-60°C for 5-6h to obtain purified medicinal pieces;

[0057] S2: Weigh the purified decoction pieces of each raw medicinal material according to the prescription, crush them with a grinder, pass them through a 20-mesh sieve, and obtain coarse powder;

[0058] S3: mixing the coarse powders prepared above evenly to prepare mixed powders;

[0059] S4: After sterilizing the mixed powder prepared above under moist heat at 105±5°C for 15 minutes, the mixed powder is divided into non-woven packaging materials to obtain 1000 bags of finished products.

[0060] Example 3

[0061] Prescription of Chinese medicine composition for relieving eye fatigue:

[0062] Kiwi vine 500g Acorus calamus 500g Mulberry leaf 150g Chrysanthemum 150g

[0063] Bupleurum 150g Poria 150g Peony bark 150g Cuscuta chinensis 150g

[0064] Schisandra 50g Ligustrum lucidum 50g Uncaria rhynchophylla 50g Taraxacum mongolicum 50g

[0065] The above-mentioned Chinese medicine composition is used to prepare an eye protection eye bag for relieving eye fatigue, and the preparation method is as follows:

[0066] S1: Select, soak, cut and dry the raw medicinal materials at 50-60°C for 5-6h to obtain purified medicinal pieces;

[0067] S2: Weigh the purified decoction pieces of each raw medicinal material according to the prescription, crush them with a grinder, pass them through a 20-mesh sieve, and obtain coarse powder;

[0068] S3: mixing the coarse powders prepared above evenly to prepare mixed powders;

[0069] S4: After sterilizing the mixed powder prepared above under moist heat at 105±5°C for 15 minutes, the mixed powder is divided into non-woven packaging materials to obtain 1000 bags of finished products.

[0070] Example 4

[0071] Prescription of Chinese medicine composition for relieving eye fatigue:

[0072]

[0073] The above-mentioned Chinese medicine composition is used to prepare an eye protection eye bag for relieving eye fatigue, and the preparation method is as follows:

[0074] S1: Select, soak, cut and dry the raw medicinal materials at 50-60°C for 5-6h to obtain purified medicinal pieces;

[0075] S2: Weigh the purified decoction pieces of each raw medicinal material according to the prescription, crush them with a grinder, pass them through a 20-mesh sieve, and obtain coarse powder;

[0076] S3: mixing the coarse powders prepared above evenly to prepare mixed powders;

[0077] S4: After sterilizing the mixed powder prepared above under moist heat at 105±5°C for 15 minutes, the mixed powder is divided into non-woven packaging materials to obtain 1000 bags of finished products.

[0078] Example 5

[0079] Prescription of Chinese medicine composition for relieving eye fatigue:

[0080]

[0081] The above-mentioned Chinese medicine composition is used to prepare an eye protection eye bag for relieving eye fatigue, and the preparation method is as follows:

[0082] S1: Select, soak, cut and dry the raw medicinal materials at 50-60°C for 5-6h to obtain purified medicinal pieces;

[0083] S2: Weigh the purified decoction pieces of each raw medicinal material according to the prescription, crush them with a grinder, pass them through a 20-mesh sieve, and obtain coarse powder;

[0084] S3: mixing the coarse powders prepared above evenly to prepare mixed powders;

[0085] S4: After sterilizing the mixed powder prepared above under moist heat at 105±5°C for 15 minutes, the mixed powder is divided into non-woven packaging materials to obtain 1000 bags of finished products.

[0086] Example 6

[0087] Prescription of Chinese medicine composition for relieving eye fatigue:

[0088]

[0089]

[0090] The above-mentioned Chinese medicine composition is used to prepare an eye protection eye bag for relieving eye fatigue, and the preparation method is as follows:

[0091] S1: Select, soak, cut and dry the raw medicinal materials at 50-60°C for 5-6h to obtain purified medicinal pieces;

[0092] S2: Weigh the purified decoction pieces of each raw medicinal material according to the prescription, crush them with a grinder, pass them through a 20-mesh sieve, and obtain coarse powder;

[0093] S3: mixing the coarse powders prepared above evenly to prepare mixed powders;

[0094] S4: After sterilizing the mixed powder prepared above under moist heat at 105±5°C for 15 minutes, the mixed powder is divided into non-woven packaging materials to obtain 1000 bags of finished products.

[0095] Example 7

[0096] Prescription of Chinese medicine composition for relieving eye fatigue:

[0097]

[0098] The above-mentioned Chinese medicine composition is used to prepare an eye protection eye bag for relieving eye fatigue, and the preparation method is as follows:

[0099] S1: Select, soak, cut and dry the raw medicinal materials at 50-60°C for 5-6h to obtain purified medicinal pieces;

[0100] S2: Weigh the purified decoction pieces of each raw medicinal material according to the prescription, crush them with a grinder, pass them through a 20-mesh sieve, and obtain coarse powder;

[0101] S3: mixing the coarse powders prepared above evenly to prepare mixed powders;

[0102] S4: After sterilizing the mixed powder prepared above under moist heat at 105±5°C for 15 minutes, the mixed powder is divided into non-woven packaging materials to obtain 1000 bags of finished products.

[0103] Example 8

[0104] Prescription of Chinese medicine composition for relieving eye fatigue:

[0105]

[0106] The above-mentioned Chinese medicine composition is used to prepare an eye protection eye bag for relieving eye fatigue, and the preparation method is as follows:

[0107] S1: Select, soak, cut and dry the raw medicinal materials at 50-60°C for 5-6h to obtain purified medicinal pieces;

[0108] S2: Weigh the purified decoction pieces of each raw medicinal material according to the prescription, crush them with a grinder, pass them through a 30-mesh sieve, and obtain coarse powder;

[0109] S3: mixing the coarse powders prepared above evenly to prepare mixed powders;

[0110] S4: After sterilizing the mixed powder obtained above under moist heat at 105±5°C for 15 minutes, the mixed powder is divided into non-woven packaging materials to obtain 1000 bags of finished products.

[0111] Example 9

[0112] Prescription of Chinese medicine composition for relieving eye fatigue:

[0113]

[0114] The above-mentioned Chinese medicine composition is used to prepare an eye protection eye bag for relieving eye fatigue, and the preparation method is as follows:

[0115] S1: Select, soak, cut and dry the raw medicinal materials at 50-60°C for 5-6h to obtain purified medicinal pieces;

[0116] S2: Weigh the purified decoction pieces of each raw medicinal material according to the prescription, crush them with a grinder, pass them through a 40-mesh sieve, and obtain coarse powder;

[0117] S3: mixing the coarse powders prepared above evenly to prepare mixed powders;

[0118] S4: After sterilizing the mixed powder prepared above under moist heat at 105±5℃ for 15 min, the mixed powder is divided into non-woven packaging materials to prepare 1000 bags of finished products.

[0119] In order to further verify the reliability of the present invention, the inventor conducted a series of investigations and experiments, the excerpts of which are as follows:

[0120] 1. Sources of Traditional Chinese Medicine Compositions

[0121] 1.1 Raw materials

[0122] The raw materials of the Chinese medicine composition are: kiwi vine, calamus, mulberry leaf, chrysanthemum, bupleurum, tuckahoe, peony bark, dodder seed, schisandra chinensis, glossy privet fruit, Uncaria rhynchophylla and dandelion.

[0123] 1.2 Basis of formula

[0124] Kiwi vines harmonize the stomach, protect the membranes and strengthen the spleen. The spleen and stomach function well, Qi and blood are produced, the five internal organs are nourished, and the essence is infused into the eyes. Acorus calamus has the essence of cold water, which can moisten the orifices of the five internal organs, nourish the five internal organs internally, and connect the nine orifices externally. Therefore, Acorus calamus is used to wake up the mind, improve intelligence, and improve eyesight and hearing. The two medicines are used together, which can not only make Qi and blood produce active, nourish the eyes, but also improve hearing and eyesight. They are both the main medicines. Mulberry leaves are sweet and cold in nature. The combination of sweetness and coldness can moisten and nourish yin to improve eyesight. Chrysanthemum enters the liver meridian and can both disperse wind-heat in the liver meridian and clear liver heat to improve eyesight. The two medicines complement each other and go straight to the upper part of the body. They work together to clear the liver and improve eyesight. The Shaoyang meridian runs behind the ear, through the cheek to the underside of the eye socket. In the early stage of eye fatigue, you may feel eye socket pain. Chaihu disperses the evil of Shaoyang half-exterior and half-interior to relieve pain. The evil of drink invades the upper part, and the clear yang does not rise, so there is dizziness. The sweet and light Poria can strengthen the spleen and benefit water, penetrate dampness and transform drink, and eliminate the source of phlegm (drink). The liver is the organ of wind and wood. The liver wind and turbid fire go up, and the symptoms of eye fatigue arise. The pungent and cold Cortex Moutan is used as the minister to clear liver fire, so all symptoms can be relieved. The five medicines are used together to clear the liver and improve eyesight, relieve pain, and stop dizziness. They are all minister medicines. The deficiency of liver and kidney essence and blood, the loss of nourishment of tendons, and the regulation is dysfunctional, resulting in dry eyes. "Shennong's Herbal Classic" records that Cuscuta chinensis "replenishes deficiencies, improves qi and strength, makes people fat and healthy, and takes it for a long time to improve eyesight, lightens the body and prolongs life." Cuscuta chinensis nourishes the liver and kidneys, improves eyesight and removes cataracts. When combined with Schisandra chinensis, it can enhance the effect of nourishing the kidney and astringing essence. When combined with Ligustrum lucidum, it nourishes the liver and kidneys, nourishes the liver and improves eyesight. The three medicines are used together to nourish the liver and kidneys, improve essence and blood, and are adjuvants. Uncaria rhynchophylla is cool in nature and mainly enters the liver meridian. It can clear liver heat and calm liver yang; Taraxacum mongolicum is bitter and cold in nature, enters the liver meridian, and has the effect of clearing the liver and improving eyesight. The combination of the two medicines can further enhance the effect of clearing the liver and improving eyesight, and can also lead the other medicines in the prescription directly to the diseased area, so it is an adjuvant. The combination of all the medicines, cold and warm, and tonic and purgative, together form a medicine that replenishes qi and blood, nourishes the liver and kidneys, and clears the liver and improves eyesight.

[0125] 2. Preparation process of eye protection eye bags

[0126] 2.1 Raw materials and packaging materials

[0127] Prescription of Chinese medicine composition (made into 1000 bags in total):

[0128]

[0129] Packaging material: non-woven fabric, in accordance with the provisions of "FZ / T 64078-2019 Melt-blown non-woven fabric"; outer bag, in accordance with the provisions of "YBB00182002-2015 Polyester low-density polyethylene pharmaceutical composite film and bag".

[0130] 2.2 Preparation method of eye protection eye bags:

[0131] (1) According to the standards and procedures of the 2020 edition of the "Chinese Pharmacopoeia" and the 2019 edition of the "Guizhou Province Traditional Chinese Medicine and Ethnic Medicine Decoction Slices Standards", the raw medicinal materials are selected (or selected, soaked, cut), dried and processed to obtain clean decoction slices.

[0132] (2) The above twelve raw materials are crushed, mixed, sterilized (moist heat, 105±5°C, 15min), and packaged to obtain the decoction pieces.

[0133] (3) Pack according to product packaging specifications and then bag and seal the boxes.

[0134] (4) Sampling inspection, packaging and storage of qualified products in a ventilated and dry warehouse.

[0135] (5) Ship from the factory in accordance with product release procedures.

[0136] See the process flow chart of eye protection eye bags Figure 1 .

[0137] 3. Clinical effect verification

[0138] 3.1 Experimental subjects and methods

[0139] 100 people with 200 eyes were randomly selected, including 176 eyes with poor vision (140 eyes with myopia, 28 eyes with hyperopia, and 8 eyes with mixed astigmatism), 12 eyes with marginal vision, and 12 eyes with normal vision. The above 100 people were evenly divided into two groups, the experimental group and the control group, each group including 88 eyes with poor vision (70 eyes with myopia, 14 eyes with hyperopia, and 4 eyes with mixed astigmatism), 6 eyes with marginal vision, and 6 eyes with normal vision.

[0140] Experimental method: After cleaning their eyes, the treatment group put the eye protection bag into the eye mask and wear it on their eyes, twice a day, each time for 20 minutes; the control group did not receive any treatment. After one month, the visual acuity refraction and near point measurements were performed on both groups. A dedicated person was responsible for each examination and a control summary was made at the end.

[0141] 3.2 Efficacy evaluation criteria

[0142] 3.2.1 Visual acuity evaluation standards

[0143] Unchanged: including those whose vision remains unchanged, improves by one line, or decreases by one line;

[0144] Decreased: vision deteriorates by two lines or more;

[0145] Effective: Those whose vision improves by two lines or more;

[0146] Basically cured: visual acuity recovery ≥ 0.9;

[0147] 3.2.2 Refractive power evaluation criteria

[0148] Refractive power decrease: Refractive power decreases by 0.5D or more after treatment;

[0149] Increased diopter: diopter increased by 0.5D or more after treatment;

[0150] Refraction remains unchanged: the refraction after treatment is the same as the original refraction or is 0.25D.

[0151] 3.3 Results and Analysis

[0152] 3.3.1 Comparative analysis of visual acuity between the treatment group and the control group

[0153] In the treatment group, 72 eyes (72%) were cured after treatment, accounting for 72%, and 28 eyes (28%) had unchanged vision. There was no decreased vision or new onset of the disease. In the control group, 24 eyes (24%) were cured after treatment, accounting for 24%, 42 eyes had unchanged vision, and 34 eyes had decreased vision. The data were statistically analyzed and quantified using the Pearson chi-square test. The X2 value was 60.8, and the P value was 0.000, reaching a very high level of significance (*** represents a 1% level of significance). The difference was statistically significant. The results are shown in Table 1. The effective rate of poor vision after treatment was 81.82%, and the recovery rate was 59.09%. The Pearson chi-square test was quantified, and the X2 value was 73.8, P<0.001, reaching a very high level of significance. The difference was statistically significant. The results are shown in Table 2.

[0154] Table 1 Comparison of visual acuity changes before and after treatment

[0155]

[0156] Table 2 Comparison of the efficacy of poor visual acuity before and after treatment

[0157]

[0158] Note: ***, **, * represent 1%, 5%, 10% significance levels respectively.

[0159] 3.3.2 Changes in refractive power before and after treatment

[0160] There were 100 eyes in the treatment group, 4 eyes were mixed astigmatism and were not included in the statistics, 12 eyes were normal vision or marginal vision, and the remaining 84 eyes were included in the statistics (70 eyes were myopic and 14 eyes were hyperopic). After treatment, the refractive power of 20 eyes decreased, accounting for 23.81%. Compared with the control group, the statistical analysis showed that X 2 =13.235, P < 0.001, which is extremely significant. The results are shown in Table 3.

[0161] Table 3 Changes in refraction before and after treatment

[0162]

[0163] 3.3.3 Results and analysis

[0164] Combined with the above experimental data, it can be seen that the total effective rate of vision after treatment is 72%, and the total effective rate of the control group is 24%. Among them, the effective rate of poor vision is 81.82%, and the recovery rate is 59.09%. After statistical processing, P<0.001 was obtained. It can be seen that the treatment group has a higher significant level than the control group, which is statistically significant, proving that the eye bag has a good therapeutic effect on myopia, astigmatism, eye fatigue and other eye diseases.

[0165] Combined with the data of refractive power changes before and after treatment, it can be seen that in the treatment group, the refractive power decreased in 20 eyes, accounting for 23.81%, and increased in 10 eyes, accounting for 11.90%; in the control group, the refractive power decreased in 6 eyes, accounting for 7.14%, and increased in 4 eyes, accounting for 4.76%. Both were very significant after statistical calculation, indicating that the eye protection bag has a certain therapeutic effect on correcting eye refractive power, and the effect is significant compared with the control group, further confirming that the eye protection bag has a good therapeutic effect on vision problems such as myopia and astigmatism.

[0166] Although the present invention has been described in detail above by means of general description, specific implementation methods and tests, it is obvious to those skilled in the art that some modifications or improvements can be made to the present invention. Therefore, these modifications or improvements made without departing from the spirit of the present invention all fall within the scope of protection claimed by the present invention.

Claims

1. A Chinese medicine composition for relieving eye fatigue, characterized in that: The invention comprises the following components in parts by mass: 30 to 50 parts of kiwi vine, 30 to 50 parts of calamus, 5 to 20 parts of mulberry leaf, 5 to 20 parts of chrysanthemum, 5 to 20 parts of bupleurum, 5 to 20 parts of poria, 5 to 20 parts of peony bark, 5 to 20 parts of dodder seed, 5 to 15 parts of schisandra chinensis, 5 to 15 parts of glossy privet fruit, 5 to 15 parts of uncaria rhynchophylla and 5 to 15 parts of dandelion.

2. The Chinese medicine composition according to claim 1, characterized in that: The invention comprises the following components in parts by mass: 40 to 50 parts of kiwi vine, 40 to 50 parts of calamus, 10 to 20 parts of mulberry leaf, 10 to 20 parts of chrysanthemum, 10 to 20 parts of bupleurum, 10 to 20 parts of poria, 10 to 20 parts of peony bark, 10 to 20 parts of dodder seed, 10 to 15 parts of schisandra chinensis, 10 to 15 parts of privet fruit, 10 to 15 parts of uncaria rhynchophylla and 10 to 15 parts of dandelion.

3. The Chinese medicine composition according to claim 2, characterized in that: The composition comprises the following components in parts by mass: 40 parts of Actinidia chinensis vine, 40 parts of Acorus calamus, 15 parts of Mulberry leaf, 15 parts of Chrysanthemum, 15 parts of Bupleurum, 15 parts of Poria, 15 parts of Paeonia suffruticosa, 15 parts of Cuscuta australis, 10 parts of Schisandra chinensis, 10 parts of Ligustrum lucidum, 10 parts of Uncaria rhynchophylla and 10 parts of Taraxacum officinale.

4. The Chinese medicine composition according to any one of claims 1 to 3, characterized in that: The components are all pure medicinal pieces after processing and preparation of medicinal materials.

5. Use of the Chinese medicine composition as claimed in claim 1 in preparing a composition for relieving eye fatigue and protecting eye bags.

6. The use according to claim 5, characterized in that: The preparation method for relieving eye fatigue and protecting eye bags comprises the following steps: preparing medicinal materials such as kiwi vine, calamus, mulberry leaf, chrysanthemum, bupleurum, poria, peony bark, dodder seed, schisandra chinensis, glossy privet fruit, Uncaria rhynchophylla and dandelion to obtain purified decoction pieces, and then crushing, mixing, sterilizing and packaging the pieces.

7. The use according to claim 6, characterized in that: The preparation method for relieving eye fatigue and protecting eye bags specifically comprises the following steps: S1: Processing and preparing the medicinal materials of Actinidia chinensis, Acorus calamus, mulberry leaf, chrysanthemum, bupleurum, Poria, peony bark, Cuscuta australis, Schisandra chinensis, Ligustrum lucidum, Uncaria rhynchophylla and Taraxacum mongolicum to obtain the purified decoction pieces; S2: Weigh the purified decoction pieces of the twelve medicinal materials prepared above by weight, grind them into powder using a grinder, and pass them through a 20-40 mesh sieve to obtain coarse powder; S3: mixing the coarse powders obtained by crushing the above-mentioned 12 medicinal material pure decoction pieces evenly to prepare a mixed powder; S4: After sterilizing the mixed powder prepared above under moist heat at 105±5°C for 15 min, divide the mixture into non-woven fabric packaging materials to obtain the product.

8. The use according to claim 7, characterized in that: The processing and preparation described in step S1 of the preparation method for relieving eye fatigue and protecting eye bags are specifically: selecting, soaking, cutting and drying the medicinal materials.

9. The use according to claim 8, characterized in that: The drying conditions for the processing and preparation in step S1 of the preparation method for relieving eye fatigue and protecting eye bags are: temperature 50-60° C., 5-6 hours.

10. The use according to claim 7, characterized in that: In the preparation method for relieving eye fatigue and protecting eye bags, the coarse powder in step S2 is obtained by passing through a 20-mesh sieve.

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