Traditional Chinese medicine pulse diagnosis instrument based on vibration energy analysis and vibration mode coefficient detection and diagnosis method thereof

Abstract

The invention discloses a traditional Chinese medicine pulse diagnosis instrument based on vibration energy analysis and vibration mode coefficient detection and a diagnosis method thereof. The invention provides a brand-new technical route for solving the design problem of the pulse diagnosis instrument. Comprising a wrist strap type automatic sampling device capable of adjusting position coordinates, a temperature array and piezoresistive touch sensor array fused composite pulse condition acquisition sensor device and a vibration energy analysis and vibration mode coefficient detection analysis system, and is used for rapidly detecting traditional Chinese medicine composite pulse conditions such as astringent pulse. The pulse condition recognition method is used for solving the core pain points of tight string and difficult distinguishing and astringent pulse in traditional Chinese medicine pulse diagnosis, and the accuracy and efficiency of pulse condition recognition are improved.

Description

Technical Field

[0001] The present invention relates to the technical field of traditional Chinese medicine pulse diagnosis, and particularly to a traditional Chinese medicine pulse diagnosis instrument and a diagnosis method based on vibration energy analysis and mode shape coefficient detection, which are used to solve the core pain points of "difficult to distinguish between stringy and tense pulses, and difficult to detect hesitant pulses" in traditional Chinese medicine pulse diagnosis, and improve the accuracy and efficiency of pulse condition recognition. Background Art

[0002] Technical Status of Traditional Chinese Medicine Pulse Diagnosis Instruments At present, traditional Chinese medicine pulse diagnosis instruments have developed from traditional manual operations into electronic and intelligent devices, which mainly use optoelectronic, piezoelectric or ultrasonic sensors to collect pulse signals and analyze pulse characteristics (such as rate, intensity, waveform, etc.) in combination with algorithms. In recent years, the introduction of Internet of Things, big data and artificial intelligence technologies has further promoted the remote monitoring and health management functions of pulse diagnosis instruments, and the product types cover household, medical and portable devices; However, the existing technologies still have limitations. The design of traditional Chinese medicine diagnosis instruments has been influenced by Western medicine electrocardiogram analysis for a long time and has been unable to get out of its misunderstanding. We can see that a large number of monographs and relevant research papers are studying pulse waves, but it is actually a big deviation to regard traditional Chinese medicine pulse conditions as pulse waves; there is a very puzzling problem that traditional Chinese medicine pulse conditions and pulse waves are completely different things. Why has the national research since 1985 invested millions to tens of millions of yuan every year, and many 985 and 211 universities have participated in it, but still only analyze pulse waves? The key problem is the research and development of sensors. A large number of scholars cannot see or observe pulse conditions. At present, the only mature single-point pressure sensors in China are available. Therefore, researchers in pulse diagnosis are only studying pulse waves. The main reason is that the market demand for tactile or pressure matrix sensors is very small, and relevant enterprises invest little in the research and development of such products, and there are almost no tactile sensors or pressure array sensors that can be used in the market. The testing and recognition of pulse conditions itself is also a very complex technology. The main difficulty is that pulse condition analysis is an interdisciplinary problem involving several disciplines, and it can only wait for the relevant knowledge to accumulate to a critical point before it may solve the problem of traditional Chinese medicine pulse diagnosis. Just like the birth of the microscope created cytology and modern medicine, the tactile-based traditional Chinese medicine pulse diagnosis instrument may bring traditional Chinese medicine into science, another brand-new medicine, "Modern Traditional Chinese Medicine".

[0003] Technical Difficulties Aimed at by Traditional Chinese Medicine Pulse Conditions (1) Lack of theoretical basis for pulse condition classification based on modern physical theory: Only in recent years has the country attached importance to traditional Chinese medicine. In the previous 40 years, traditional Chinese medicine was almost on the verge of extinction. Due to the lack of capital investment, the research on traditional Chinese medicine pulse conditions has been stagnant. Until now, the traditional Chinese medicine community has not given a popularly convincing explanation of the modern physical principles of traditional Chinese medicine pulse conditions. We all understand that without a physical basis, the research and development of instruments is basically impossible; (2) Traditional pulse diagnosis instruments rely on a single sensor signal (such as pressure or optoelectronic signal), making it difficult to comprehensively capture complex pulse characteristics, especially the subtle differences of the hesitant pulse. Moreover, sensors are products highly dependent on industrial foundation capabilities, and the lack of pulse diagnosis sensors also severely restricts the development of traditional Chinese medicine pulse diagnosis instruments; (3) Poor algorithm universality: Existing algorithms are mostly trained based on standard pulse databases and have weak adaptability to individual differences (such as the special pulses of patients with hyperlipidemia); (4) Insufficient integration of traditional Chinese medicine theory: Most devices do not deeply combine the clinical experience of traditional Chinese medicine pulse diagnosis and lack quantitative analysis of the hesitant pulse characteristics of "like scraping bamboo with a light knife" (tremor sensation, blood flow resistance). To put it bluntly, traditional Chinese medicine currently lacks a theory based on modern science. Professor Yao Meiling, a famous traditional Chinese medicine doctor in Jiangxi, clearly states in his book "Sixteen Lectures on Clinical Pulse Science" that traditional Chinese medicine is so backward and everything depends on feeling. Due to the lack of modern instruments, the research on pulses is only based on human tactile sensation.

[0004] Clinical pain points in the identification of the hesitant pulse There is a saying in the traditional Chinese medicine field that "it is difficult to distinguish between the taut and tight pulses, and it is difficult to diagnose the hesitant pulse". As an important pathological pulse in traditional Chinese medicine diagnosis, the hesitant pulse is mainly divided into two categories: (1) The hesitant pulse with a finger feeling like scraping bamboo with a steel knife: There is an obvious tremor in the finger feeling, which is commonly seen in qi stagnation and blood stasis or cardiovascular and cerebrovascular diseases; (2) The hesitant pulse of hyperlipidemia type: The pulse is slippery with a hint of hesitation, which is related to the increased blood viscosity caused by abnormal blood lipids. Traditional pulse diagnosis relies on the experience of physicians. This kind of pulse can only be identified by finger feeling, and at least 20 years of clinical experience in pulse diagnosis is required. However, there are problems of strong subjectivity and poor repeatability; existing devices are difficult to distinguish between the two types of hesitant pulses due to the single dimension of signal acquisition, resulting in a risk of misdiagnosis. Summary of the invention

[0005] Based on the problems existing in the background technology, the present invention proposes a brand-new traditional Chinese medicine pulse diagnosis instrument and its diagnosis method based on vibration energy analysis and vibration mode coefficient detection to solve the problems of the background technology.

[0006] Object of the invention The present invention proposes a brand-new technical route to solve the design problem of the pulse diagnosis instrument. It includes a wristband type automatic sampling device with adjustable position coordinates, a composite pulse acquisition sensor device integrating a temperature array and a piezoresistive tactile sensor array, and a vibration energy analysis and pulse vibration mode coefficient detection system for quickly detecting complex traditional Chinese medicine pulses such as the hesitant pulse.

[0007] Technical solution (1) An improved sensor acquisition structure design, characterized in that the sensor base is composed of an air cushion bag or a spring support or a reed (such as Figure 2 、 Figure 3As shown in the figure, the hard sensor base is made to fully fit the three positions of cun, guan, and chi of the radial artery through short-distance physical deformation. A composite multi-parameter sensor is designed for the pulse signal acquisition device, and the specific content is as follows: Tactile sensor: To capture the change in the physical centroid of the pulse body, three-dimensional pulse diagram technology is required to observe the physical essence of the stagnation of traditional Chinese medicine pulses; Micro-vibration sensor: Detect the abnormal energy pulsation range of vibration within a certain frequency band of the pulse, excluding the frequency ranges of heartbeat and respiration, and identify the tremor type of unsmooth pulse, such as the feeling like scraping bamboo with a steel knife mentioned in traditional Chinese medicine; Vibration mode coefficient detection device: Through the analysis of the pressure fluctuation of the radial artery pressure gradient field, the unsmooth pulse of hyperlipidemia type is identified by calculating the vibration mode coefficient of the pressure gradient field. When the value of the vibration mode coefficient is greater than a certain rated threshold, it can be determined as the unsmooth pulse of hyperlipidemia type; (2) Feature fusion and classification algorithm Extract the regional characteristics of the vibration energy distribution of the pulses at the three positions of cun, guan, and chi of the radial artery, analyze them with the characteristics of the vibration energy of the pulses at the three positions of cun, guan, and chi of the normal pulse type, and combine traditional Chinese medicine theory to use the normal to measure the abnormal, highlighting the abnormal characteristics of the unsmooth pulse type for rapid identification of unsmooth pulses and other pulses. In the first step, the optical flow method is used to detect the video file in which the pulse vibration is converted from touch to vision, and it is trained in combination with the clinical data set (samples of unsmooth pulse of hyperlipidemia type) marked by traditional Chinese medicine experts for the computer to automatically classify the centroid change of the pulse. In the second step, by analyzing the centroid change rate of the three-dimensional pulse diagram of the pulse body at the cun, guan, and chi positions, that is, the centroid movement distance of the pulse body per unit time, to distinguish the typical characteristics of the highly coagulated unsmooth pulse. The specific process is to calculate the centroid coordinates of the pulse at the starting stage of a pulse cycle and calculate the centroid coordinates of the pulse at the end stage of a pulse cycle, and use the calculated distance of the centroid moving per unit time as the identification index to distinguish the highly coagulated unsmooth pulse, output the classification result and confidence level, and assist the doctor in making decisions; (3) Wristband type automatic sampling device with adjustable position coordinates The pulse is collected by simulating the tactile method of fingers. The collection device is optimized, the position adjustment of the collection sensor is redesigned, and a local fine-tuning function is added. On the basis of the wristband type collector, by adding slide rails (such as Figure 4 , Figure 5 , Figure 7 shown in the figure), it is designed so that the tactile sensor can locally fine-tune the position coordinates after wearing the pulse diagnosis instrument. It is a system in which the wristband base and the sensor linear motor feeding system are separated and connected by a chute. The wristband base is fixed in advance at the cun, guan, and chi positions of the wrist before testing, and the sensor system can be finely adjusted radially along the radial artery through the chute to ensure that the midline of the sensor array coincides with the pulse ridge of the pulse body; the chute is equipped with an adjustable damping structure to ensure its certain stability of stopping as it moves; (4)A sampling device that adjusts the spacing and inclination of the cun-guan-chi three-part sampling device through the deformation of a rigid spring or elastic hose During actual traditional Chinese medicine pulse diagnosis, a person's fingers are very flexible and can be flexibly changed for patients with different arm lengths and body types to adapt to patients of different heights and weights. In the present invention, three sampling devices with linear motors are flexibly connected together to adapt to the spacing of the cun-guan-chi of the radial artery at the wrist of different lengths; specifically, stainless steel springs or elastic thin tubes, sliding tubes, and head telescopic parts are used. Through the cooperation of these three things, different spacings and inclinations of the three sampling devices are adjusted (as shown in Figure 6 、 Figure 7 ); through the method of bending and deforming the elastic hose, the sampling device can be used at the wrists of people with different arm lengths and body types.

[0008] Technical innovation points Composite sensor: Breaking through the limitations of a single sensor, using a composite sensor integrated with pressure, vibration, and temperature to comprehensively quantify the finger feeling characteristics and hemodynamic characteristics of traditional Chinese medicine pulses. Using the micro-deformation technology of metal reed pieces (as shown in Figure 2 、 Figure 3 ), the position adjustment problem of 6 coordinates in the space of the sensor is solved; by improving the structure of the wristband-type pulse acquisition device and introducing a micro-displacement slide with a damping system, it is used to solve the space positioning problem of the pulse acquisition device; Highlighting the identification of typical pulses based on physical characteristic parameters, that is, analyzing the pulses with physical quantities, breaking the conventional practice of identifying pulses through the analysis of characteristic values of pulse wave diagrams. For example, using the vibration mode coefficient to identify the astringent pulse of hyperlipidemia. When the value of the vibration mode coefficient is greater than a certain rated threshold, it can be determined as the astringent pulse of hyperlipidemia. Some typical pulses in traditional Chinese medicine have their prominent typical physical characteristics. For example, the traditional identification of the astringent pulse is mainly based on the finger feeling of tremor. The tremor feeling in the finger feeling is analyzed in vibration dynamics as a vibration energy different from the vibration caused by the heart rate and breathing frequency bands; Introducing the tactile-to-visual technology to reproduce traditional Chinese medicine pulses and directly visualize the pulses of traditional Chinese medicine. Thus, it helps to understand that some basic concepts about form and momentum in traditional Chinese medicine are not groundless. It has a certain physical basis. The research on pulses by the ancients was a research based on objective facts, and everything was built on a materialist basis, proving that traditional Chinese medicine pulse science is a science, not something mysterious. Specific implementation methods

[0009] Hardware Deployment: A composite sensor is adopted in the design of the sensor. A vibration sensor, a tactile sensor array, and a temperature sensor array are integrated on the composite sensor to simulate the touch of a human finger. The sensor device is loaded on a precision linear motor to simulate different finger techniques such as floating, middle, and sinking of a human finger. Signal Acquisition and Processing: The technology of synchronous data acquisition is adopted. In order to simulate the functions of a human finger to the greatest extent, the signal acquisition and processing system of the pulse diagnosis instrument uses a 210-channel synchronous signal processing circuit to ensure that the signals can simulate the sensory touch of a human finger to the greatest extent. Using Physical Feature Quantities as the Basic Method for Pulse Pattern Recognition: The unique physical feature of the hesitant pulse is the vibration energy at other frequencies outside the heart rate. This is the physical basis for the hesitant pulse to have the feeling of a steel knife scraping bamboo. Traditional Chinese medicine mainly relies on the presence of a tremor feeling in the finger sensation to identify the hesitant pulse.

[0010] Beneficial Effects Accurate Classification: The recognition accuracy of the two types of hesitant pulses is increased to over 95% (about 40% for traditional devices). Clinical Practicality: Through simple training, clinical Chinese medicine practitioners can master the ability to analyze hesitant pulses, taut pulses, and tense pulses, which might have required 20 years of practice in the past, greatly improving the recognition ability of complex pulse patterns in traditional Chinese medicine. Standardized Promotion: Promote the objectification and internationalization of traditional Chinese medicine pulse diagnosis, in line with the national development strategy of traditional Chinese medicine. Description of the Drawings

[0011] Figure 1 Composite Pulse Pattern Acquisition Sensor Device Composite Pulse Pattern Acquisition Sensor Device; Figure 2 Composite Pulse Pattern Acquisition Sensor Device Airbag-Type Composite Pulse Pattern Acquisition Sensor Device; Figure 3 Composite Pulse Pattern Acquisition Sensor Device Reed-Type Composite Pulse Pattern Acquisition Sensor Device; Figure 4 Exploded View of the Automatic Sampling Device of the Wristband-Type Pulse Pattern Acquisition Device Sampling Device; Figure 5 Side View of the Automatic Sampling Device of the Wristband-Type Pulse Pattern Acquisition Device Sampling Device; Figure 6 Side View of the Automatic Sampling Device of the Wristband-Type Pulse Pattern Acquisition Device Sampling Device with Trigeminy; Figure 7 Schematic Diagram of the Installation Position of the Automatic Sampling Device of the Wristband-Type Pulse Pattern Acquisition Device.

Claims

1. A Chinese medicine pulse diagnosis instrument and a diagnostic method based on vibration energy analysis and vibration mode coefficient detection, which includes a wristband-type automatic sampling device with adjustable position coordinates, a composite pulse acquisition sensor device integrating a temperature array and a tactile sensor array, and a vibration energy anomaly analysis and vibration mode coefficient analysis system, and is used for rapid detection of Chinese medicine composite pulses such as astringent pulses.

2. A Chinese medicine pulse diagnosis instrument based on vibration energy analysis and vibration mode coefficient detection as claimed in claim 1, characterized in that A wristband-type automatic sampling device with adjustable position coordinates is a system in which a wristband base and a sensor linear motor feed system are separated and connected via a slide. The wristband base is fixed at the wrist inch, guan and chi positions before testing. The sensor system can be fine-tuned in the radial direction of the radial artery through the slide to ensure that the midline of the sensor array coincides with the ridge of the pulse body; the slide has an adjustable damping structure to ensure a certain stability when moving and stopping.

3. A Chinese medicine pulse diagnosis instrument based on vibration energy analysis and pulse centroid trajectory detection as claimed in claim 1, characterized in that The sensor base is composed of an air cushion bag or a spring support or a reed, and the hard sensor base is completely fitted to the three parts of the radial artery, namely, Cun, Guan and Chi, through short-distance physical deformation; a composite pulse acquisition sensor device is a fusion of a temperature array and a piezoresistive tactile sensor array; the composite pulse acquisition sensor device is composed of 14 rows and 5 columns of tactile and pressure sensor micro-units and a column of 9 micro temperature sensors, arranged in a rectangular shape.

4. A Chinese medicine pulse diagnosis instrument based on vibration energy analysis and pulse centroid trajectory detection as claimed in claim 1, characterized in that In order to flexibly link three sampling devices with linear motors together to adapt to the distance between the radial artery inch, guan and chi of wrists of different lengths, stainless steel springs or elastic thin tubes and sliding tubes, and head telescopic parts are used. Through the cooperation of these three things, different distances and inclinations of the three sampling devices can be adjusted; by bending and deforming the elastic hose, the sampling equipment can be used on the wrists of people with different arm lengths and fat or thin bodies.

5. A Chinese medicine pulse diagnosis method based on vibration energy analysis and pulse centroid trajectory detection as claimed in claim 1, characterized in that An algorithm and steps for identifying astringent pulse: the first step is to analyze the autopower spectral density function of the transmural pressure of the radial artery Cun, Guan and Chi parts, exclude the frequency bands of the basic frequency and the frequency multiples except the heart rate and the respiratory rate, and check whether there are other periodic frequency energies except these two frequencies, and whether the energy of these periodic frequency pulsations exceeds a preset threshold, and then judge whether there is a fixed stop phenomenon within one minute, which is the knotted and intermittent pulse mentioned in traditional Chinese medicine. If there is no knotted and intermittent pulse phenomenon, then it can be judged that the current pulse is a stringy pulse with the typical characteristics of a steel knife scraping bamboo type astringent pulse; the second step The analysis is to calculate the centroid coordinates of the three-dimensional pulse formed by the mechanism of touch at the beginning stage of one cycle of the pulse, and calculate the centroid coordinates of the pulse at the end stage of one cycle of the pulse. The distance moved by the centroid per unit time is used as the basis for identification. At the same time, it is calculated whether the vibration mode coefficient of the pulse vibration here exceeds a certain threshold. If the distance moved by the centroid of the three-dimensional pulse per unit time and the vibration mode coefficient of the pulse vibration are within the specified threshold range, these two indicators can be used as the basis for judging a high-coagulation type of wiry pulse. In the third step, if both the first and second steps exist, it can be judged as a typical wiry pulse.

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